Detailed information for compound 647157

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 341.404 | Formula: C19H23N3O3
  • H donors: 1 H acceptors: 1 LogP: 3.3 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1N1CCN(CC1)N=Cc1cccc(c1O)OC
  • InChi: 1S/C19H23N3O3/c1-24-17-8-4-3-7-16(17)21-10-12-22(13-11-21)20-14-15-6-5-9-18(25-2)19(15)23/h3-9,14,23H,10-13H2,1-2H3/b20-14-
  • InChiKey: GXHJDFKWUBEMIV-ZHZULCJRSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.3342 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0421 0.0335
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0901 0.1153
Loa Loa (eye worm) hypothetical protein 0.0145 0.375 0.5744
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.022 0.0659
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0421 0.0571
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0485 0.0715
Schistosoma mansoni deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0173 0.461 0.4561
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.3342 0.3282
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0428 0.0586
Mycobacterium ulcerans hypothetical protein 0.0035 0.0421 0.126
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0173 0.461 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0121 0.3021 0.2959
Echinococcus granulosus expressed conserved protein 0.0112 0.2746 0.4054
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.022 0.0118
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0485 0.0744
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0428 0.0586
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0485 0.05
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.3342 0.7145
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0485 0.0715
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0168 0.0257
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.3342 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0225 0.6197 1
Plasmodium vivax deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0173 0.461 1
Trypanosoma brucei glucosidase, putative 0.0037 0.0485 0.1001
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0428 0.0586
Schistosoma mansoni myelin transcription factor 1 myt1 0.0066 0.1344 0.1266
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0485 0.1001
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0421 0.0571
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0421 0.068
Mycobacterium leprae PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE) 0.006 0.1176 0.3061
Loa Loa (eye worm) dUTP diphosphatase 0.0173 0.461 0.7061
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0704 0.0844
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0485 0.0715
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.022 0.0659
Brugia malayi phosphofructokinase 0.0131 0.3342 0.499
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0421 0.068
Loa Loa (eye worm) hypothetical protein 0.0035 0.0421 0.0645
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0704 0.0844
Brugia malayi Niemann-Pick C1 protein precursor 0.0119 0.2966 0.4399
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0485 0.0715
Loa Loa (eye worm) hypothetical protein 0.0066 0.1344 0.2059
Echinococcus granulosus polycomb protein SCMH1 0.0058 0.1101 0.1468
Brugia malayi AMP-binding enzyme family protein 0.0029 0.022 0.0082
Mycobacterium leprae Probable lipase LipE 0.0035 0.0421 0.0644
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0704 0.1079
Schistosoma mansoni alpha-glucosidase 0.0145 0.3756 0.37
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.022 0.0659
Entamoeba histolytica hypothetical protein 0.006 0.1176 0.2269
Toxoplasma gondii ABC1 family protein 0.0035 0.0421 0.0571
Schistosoma mansoni hypothetical protein 0.0164 0.4341 0.429
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.6528 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0415 0.0389
Loa Loa (eye worm) MBCTL1 0.0066 0.1344 0.2059
Loa Loa (eye worm) hypothetical protein 0.0035 0.0421 0.0645
Onchocerca volvulus 0.0097 0.2311 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.022 0.0659
Loa Loa (eye worm) hypothetical protein 0.0029 0.022 0.0337
Mycobacterium tuberculosis Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase) 0.006 0.1176 0.1897
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.3342 0.7145
Brugia malayi Muscleblind-like protein 0.0145 0.375 0.5631
Brugia malayi AMP-binding enzyme family protein 0.0029 0.022 0.0082
Brugia malayi Glycosyl hydrolases family 31 protein 0.0168 0.4469 0.6763
Echinococcus multilocularis protein patched 0.0051 0.0901 0.1153
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.3342 1
Schistosoma mansoni hypothetical protein 0.0049 0.0845 0.0763
Echinococcus multilocularis expressed conserved protein 0.0112 0.2746 0.4054
Loa Loa (eye worm) phosphofructokinase 0.0131 0.3342 0.5119
Plasmodium falciparum flap endonuclease 1 0.0027 0.0168 0.0364
Entamoeba histolytica hypothetical protein 0.0113 0.2784 0.5889
Echinococcus multilocularis Niemann Pick C1 protein 0.017 0.4517 0.6839
Loa Loa (eye worm) hypothetical protein 0.0051 0.0901 0.138
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0818 0.1022
Schistosoma mansoni hypothetical protein 0.0049 0.0845 0.0763
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.4469 0.6763
Echinococcus multilocularis geminin 0.0164 0.4341 0.6561
Loa Loa (eye worm) hypothetical protein 0.0035 0.0421 0.0645
Brugia malayi mbt repeat family protein 0.0058 0.1101 0.1468
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0428 0.0928
Entamoeba histolytica hypothetical protein 0.0113 0.2784 0.5889
Entamoeba histolytica deoxycytidine triphosphate deaminase, putative 0.006 0.1176 0.2269
Mycobacterium tuberculosis Conserved protein 0.0035 0.0421 0.068
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.3342 0.7145
Onchocerca volvulus 0.0035 0.0421 0.0962
Schistosoma mansoni survival motor neuron protein 0.0048 0.0814 0.0731
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0421 0.0799
Loa Loa (eye worm) hypothetical protein 0.0236 0.6528 1
Mycobacterium ulcerans lipase LipD 0.0035 0.0421 0.126
Onchocerca volvulus 0.0035 0.0421 0.0962
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0485 0.0715
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0428 0.0928
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0173 0.461 1
Brugia malayi hypothetical protein 0.0035 0.0415 0.0389
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0421 0.068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0704 0.0621
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0428 0.0928
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0227 0.6253 0.9568
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.3101 0.475
Entamoeba histolytica hypothetical protein 0.0035 0.0415 0.0557
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.3342 0.6968
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0421 0.0571
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0485 0.05
Entamoeba histolytica hypothetical protein 0.0173 0.461 1
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0119 0.2966 0.6298
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0421 0.0645
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0485 0.0715
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0173 0.461 1
Echinococcus granulosus Niemann Pick C1 protein 0.017 0.4517 0.6839
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.022 0.0118
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0485 0.05
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0485 0.0715
Brugia malayi mbt repeat family protein 0.0058 0.1101 0.1468
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0066 0.1344 0.1849
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, putative 0.006 0.1176 0.2269
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0421 0.0335
Loa Loa (eye worm) hypothetical protein 0.0035 0.0421 0.0645
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.1101 0.1021
Schistosoma mansoni patched 1 0.0051 0.0901 0.0819
Echinococcus granulosus lysosomal alpha glucosidase 0.0168 0.4469 0.6763
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0818 0.1022
Chlamydia trachomatis deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0173 0.461 1
Mycobacterium tuberculosis Conserved protein 0.0035 0.0421 0.068
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.022 0.0355
Brugia malayi beta-lactamase family protein 0.0035 0.0421 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0901 0.1651
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.6528 1
Brugia malayi beta-lactamase 0.0035 0.0421 0.0399
Trichomonas vaginalis deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0173 0.461 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0353 0.0541
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0421 0.126
Echinococcus granulosus SAM and MBT domain containing protein 0.0058 0.1101 0.1468
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0814 0.1016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0704 0.0621
Loa Loa (eye worm) hypothetical protein 0.0029 0.022 0.0337
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0058 0.1101 0.1021
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0421 0.068
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0168 0.4469 0.6846
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.022 0.0118
Entamoeba histolytica hypothetical protein 0.0035 0.0415 0.0557
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0428 0.0928
Mycobacterium ulcerans beta-lactamase 0.0035 0.0421 0.126
Echinococcus multilocularis dUTP pyrophosphatase 0.0173 0.461 0.6984
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.022 0.0165
Onchocerca volvulus 0.0048 0.0814 0.2839
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.3342 0.5119
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.3101 0.475
Loa Loa (eye worm) mbt repeat family protein 0.0058 0.1101 0.1687
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.022 0.0659
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0421 0.0399
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0428 0.0586
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.022 0.0659
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0485 0.1001
Entamoeba histolytica hypothetical protein 0.0035 0.0415 0.0557
Trichomonas vaginalis esterase, putative 0.0035 0.0421 0.0571
Echinococcus granulosus dUTP pyrophosphatase 0.0173 0.461 0.6984
Echinococcus granulosus geminin 0.0164 0.4341 0.6561
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.3342 0.7145
Brugia malayi CHE-14 protein 0.0051 0.0901 0.1153
Treponema pallidum deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) 0.0173 0.461 1
Echinococcus multilocularis polycomb protein SCMH1 0.0058 0.1101 0.1468
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0818 0.1253
Toxoplasma gondii deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0173 0.461 1
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0421 0.0644
Brugia malayi hypothetical protein 0.0236 0.6528 1
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.3342 0.499
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0428 0.0586
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0066 0.1344 0.1849
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0428 0.0586
Loa Loa (eye worm) beta-lactamase 0.0035 0.0421 0.0645
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0173 0.461 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0119 0.2966 0.4399
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.3342 0.7145
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.3342 0.7145
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0704 0.0621
Entamoeba histolytica hypothetical protein 0.0035 0.0415 0.0557
Onchocerca volvulus 0.0035 0.0421 0.0962
Echinococcus multilocularis SAM and MBT domain containing protein 0.0058 0.1101 0.1468
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.022 0.0165
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0066 0.1344 0.1849
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0901 0.1153
Schistosoma mansoni sex comb on midleg homolog 0.0058 0.1101 0.1021
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0428 0.0586
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0704 0.0844
Mycobacterium ulcerans deoxyuridine 5'-triphosphate nucleotidohydrolase 0.006 0.1176 0.3518
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0421 0.0914
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.3342 0.3282
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0421 0.0799
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.3342 0.499
Schistosoma mansoni hypothetical protein 0.0049 0.0845 0.0763
Loa Loa (eye worm) hypothetical protein 0.0119 0.2966 0.4543
Mycobacterium ulcerans hypothetical protein 0.0029 0.022 0.0659
Echinococcus multilocularis muscleblind protein 1 0.0145 0.375 0.5631
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0173 0.461 1
Echinococcus granulosus Niemann Pick C1 protein 0.0119 0.2966 0.4399
Chlamydia trachomatis deoxycytidine triphosphate deaminase 0.006 0.1176 0.255
Echinococcus multilocularis muscleblind protein 0.0145 0.375 0.5631
Brugia malayi 6-phosphofructokinase 0.0131 0.3342 0.499
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0428 0.0586
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0353 0.0292
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0428 0.0586
Leishmania major hypothetical protein, conserved 0.0035 0.0421 0.0799
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0421 0.0799
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0704 0.0844
Wolbachia endosymbiont of Brugia malayi dUTPase 0.0173 0.461 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.125 0.1915
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0485 0.0715
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0485 0.1001
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0421 0.0399
Loa Loa (eye worm) hypothetical protein 0.0029 0.022 0.0337
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.3342 0.5392
Schistosoma mansoni hypothetical protein 0.0049 0.0845 0.0763
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0704 0.0844
Entamoeba histolytica hypothetical protein 0.0173 0.461 1
Schistosoma mansoni hypothetical protein 0.0035 0.0415 0.0329
Schistosoma mansoni alpha glucosidase 0.0037 0.0485 0.04
Schistosoma mansoni alpha-glucosidase 0.0145 0.3756 0.37
Brugia malayi dUTP diphosphatase 0.0173 0.461 0.6984
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0227 0.6253 0.9568
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0428 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0421 0.0399
Brugia malayi 6-phosphofructokinase 0.0131 0.3342 0.499
Loa Loa (eye worm) hypothetical protein 0.0058 0.1101 0.1687
Schistosoma mansoni hypothetical protein 0.0033 0.0353 0.0266
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0485 0.0715
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.3342 1
Echinococcus granulosus muscleblind protein 0.0145 0.375 0.5631
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0421 0.068
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0173 0.461 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0485 0.0715
Echinococcus granulosus histone acetyltransferase MYST2 0.0066 0.1344 0.1849
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.022 0.0355
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.3342 1
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0415 0.0329
Loa Loa (eye worm) hypothetical protein 0.0035 0.0421 0.0645
Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0173 0.461 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0058 0.1101 0.4216
Loa Loa (eye worm) hypothetical protein 0.0035 0.0421 0.0645
Mycobacterium tuberculosis Conserved protein 0.0035 0.0421 0.068
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0421 0.126
Echinococcus multilocularis lysosomal alpha glucosidase 0.0168 0.4469 0.6763
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.022 0.0659
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0415 0.0389
Brugia malayi AMP-binding enzyme family protein 0.0029 0.022 0.0082
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.022 0.0165
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0168 0.0364
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0421 0.0571
Loa Loa (eye worm) hypothetical protein 0.0145 0.375 0.5744
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0421 0.068
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0485 0.0715
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0901 0.1153
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0428 0.0928
Schistosoma mansoni hypothetical protein 0.0164 0.4341 0.429
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0428 0.0586
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.3342 0.5119
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0901 0.138
Echinococcus multilocularis protein dispatched 1 0.0058 0.112 0.1498
Echinococcus multilocularis histone acetyltransferase MYST2 0.0066 0.1344 0.1849
Brugia malayi MH2 domain containing protein 0.0123 0.3101 0.4612
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0428 0.0928
Mycobacterium ulcerans deoxycytidine triphosphate deaminase 0.006 0.1176 0.3518
Brugia malayi beta-lactamase family protein 0.0035 0.0421 0.0399
Schistosoma mansoni hypothetical protein 0.0048 0.0814 0.0731
Loa Loa (eye worm) hypothetical protein 0.0048 0.0818 0.1253
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0421 0.0571
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.3342 0.7145
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0428 0.0586
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0421 0.068
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0485 0.0715
Onchocerca volvulus 0.0058 0.1101 0.4216

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.