Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.1886 | 0.1886 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.1886 | 0.1886 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.1886 | 0.1886 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.1886 | 0.1886 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.1886 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.1886 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1886 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1886 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.1886 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.1886 | 0.1886 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1886 | 0.5 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.1886 | 0.1886 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0061 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 1 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.1886 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.1886 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.1886 | 0.1886 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.1886 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.1886 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1886 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.1886 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 1 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.1886 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.1886 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.