Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.2139 | 0.372 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0939 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.5326 | 0.615 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2139 | 0.2052 |
Onchocerca volvulus | 0.0032 | 0.4393 | 0.5 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.8073 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4393 | 0.4331 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.8073 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4678 | 0.4619 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.5326 | 0.616 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.2139 | 0.1704 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.2139 | 0.372 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.5326 | 0.5275 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2139 | 0.1681 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4678 | 0.4619 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2139 | 0.2052 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2139 | 0.2052 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.8867 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.2139 | 0.1681 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.4678 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.8073 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.2139 | 0.2052 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4393 | 0.4842 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4393 | 0.4856 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.2139 | 0.372 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.4678 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0634 | 0.0531 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.8073 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.2139 | 0.372 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0525 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0939 | 0.0754 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.2139 | 0.372 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.2139 | 0.372 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.2139 | 0.1704 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.