Detailed information for compound 648045

Basic information

Technical information
  • TDR Targets ID: 648045
  • Name: 1-[2-(3-methoxyphenoxy)ethoxy]-2-nitrobenzene
  • MW: 289.283 | Formula: C15H15NO5
  • H donors: 0 H acceptors: 2 LogP: 3.36 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)OCCOc1ccccc1[N+](=O)[O-]
  • InChi: 1S/C15H15NO5/c1-19-12-5-4-6-13(11-12)20-9-10-21-15-8-3-2-7-14(15)16(17)18/h2-8,11H,9-10H2,1H3
  • InChiKey: BCGVJIQNNWHELT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2-(3-methoxyphenoxy)ethoxy]-2-nitro-benzene
  • SMR000195210
  • MLS000572903
  • ZINC02986929

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens breast cancer 1, early onset Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Echinococcus granulosus tar DNA binding protein 0.0076 0.0146 0.029
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Onchocerca volvulus 0.0144 0.031 0.1334
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0014 0.0025
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0073 0.0146
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Echinococcus multilocularis somatostatin receptor 0.0066 0.0121 0.0118
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0066 0.0121 0.0208
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0014 0.0022
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0047 0.0073 0.0146
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0209 0.0471 0.0949
Brugia malayi AKH receptor 0.0066 0.0121 0.0208
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0121 0.0238
Giardia lamblia Kinase, CMGC CLK 0.006 0.0107 0.6869
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0535 0.1266 1
Echinococcus multilocularis para nitrobenzyl esterase 0.0209 0.0471 0.0468
Echinococcus granulosus GPCR family 2 0.008 0.0155 0.0308
Onchocerca volvulus 0.0066 0.0121 0.0507
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0047 0.0073 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0047 0.0073 0.0146
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0149 0.0323 0.0321
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0326 0.0754 0.0752
Trypanosoma brucei unspecified product 0.0053 0.009 0.075
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0066 0.0121 0.0208
Brugia malayi hypothetical protein 0.004 0.0057 0.0098
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Loa Loa (eye worm) hypothetical protein 0.008 0.0155 0.0512
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0067 0.1088
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0112 0.0478
Onchocerca volvulus 0.0209 0.0471 0.2034
Echinococcus multilocularis 0.0059 0.0103 0.0101
Schistosoma mansoni chromodomain helicase DNA binding protein 0.002 0.0008 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0029 0.005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0014 0.0022
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0029 0.003 0.0206
Echinococcus granulosus tachykinin peptides receptor 99D 0.0066 0.0121 0.0238
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0195 0.3765
Loa Loa (eye worm) hypothetical protein 0.0173 0.0382 0.1273
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0007 0.0011
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0103 0.1591
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0121 0.0238
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Plasmodium falciparum replication factor C subunit 1, putative 0.004 0.0057 0.3818
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0121 0.0118
Echinococcus multilocularis protein patched 0.0129 0.0275 0.0272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0014 0.0037
Loa Loa (eye worm) GABA receptor subunit 0.0171 0.0377 0.1254
Brugia malayi G protein-coupled receptor F59B2.13 0.0066 0.0121 0.0208
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0029 0.0278
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0047 0.0073 0.0237
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0073 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0019
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.002 0.0123
Entamoeba histolytica protein kinase, putative 0.0089 0.0176 0.2522
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0103 0.6558
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0035 0.0046 0.0759
Echinococcus multilocularis cathepsin L cysteine protease 0.0044 0.0067 0.0064
Schistosoma mansoni neuroligin 3 (S09 family) 0.0209 0.0471 0.0949
Echinococcus multilocularis acetylcholinesterase 0.124 0.2985 0.2983
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Brugia malayi Niemann-Pick C1 protein precursor 0.0301 0.0694 0.1198
Loa Loa (eye worm) hypothetical protein 0.0088 0.0173 0.0573
Toxoplasma gondii ATPase, AAA family protein 0.004 0.0057 0.0856
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0073 0.1115
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0047 0.0073 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0237 0.0539 0.1798
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus two pore calcium channel protein 1 0.0047 0.0073 0.0142
Echinococcus granulosus neuropeptide receptor 0.0066 0.0121 0.0238
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.004 0.0057 0.0855
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0035 0.0046 0.0759
Trypanosoma brucei RNA helicase, putative 0.0433 0.1016 1
Brugia malayi Patched related family protein 12 0.0018 0.0004 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0195 0.3765
Loa Loa (eye worm) voltage-gated calcium channel 0.0047 0.0073 0.0237
Echinococcus granulosus expressed conserved protein 0.0283 0.065 0.1307
Schistosoma mansoni blooms syndrome DNA helicase 0.0034 0.0042 0.0083
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0047 0.0073 0.0584
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0195 0.3848
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0147 0.2864
Plasmodium falciparum protein serine/threonine kinase-1 0.006 0.0107 0.725
Echinococcus granulosus neuropeptide FF receptor 2 0.0066 0.0121 0.0238
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0024 0.0096
Brugia malayi ion channel NompC 0.0047 0.0073 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Onchocerca volvulus 0.0066 0.0121 0.0507
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.002 0.005
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.006 0.0107 0.1935
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Loa Loa (eye worm) patched family protein 0.0018 0.0004 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.124 0.2985 0.6025
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Onchocerca volvulus 0.0028 0.0029 0.0107
Brugia malayi SET domain containing protein 0.0019 0.0006 0.001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0066 0.0121 0.0118
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.0195 0.3848
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.001 0.0025
Brugia malayi Carboxylesterase family protein 0.0209 0.0471 0.0812
Brugia malayi Patched related family protein 10 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0048 0.0804
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0014 0.0022
Entamoeba histolytica hypothetical protein 0.004 0.0057 0.0805
Echinococcus granulosus fmrfamide receptor 0.0066 0.0121 0.0238
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0155 0.0337 0.0582
Trichomonas vaginalis phosphofructokinase, putative 0.0218 0.0491 0.2132
Schistosoma mansoni acetylcholine receptor-related 0.0155 0.0337 0.0679
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0047 0.0073 0.007
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0007 0.0004
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0066 0.0121 0.0238
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0047 0.0073 0.0126
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Echinococcus multilocularis calcium activated potassium channel 0.0048 0.0077 0.0074
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0121 0.0241
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.002 0.0224
Echinococcus granulosus BC026374 protein S09 family 0.0209 0.0471 0.0945
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0029 0.0408
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0029 0.0408
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Brugia malayi Dopamine receptor 0.0066 0.0121 0.0208
Schistosoma mansoni amine GPCR 0.0066 0.0121 0.0241
Plasmodium vivax unspecified product 0.0023 0.0015 0.0084
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0326 0.0754 0.1518
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0004 0.0218
Echinococcus multilocularis serotonin receptor 0.0066 0.0121 0.0118
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0155 0.0337 0.0582
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0179 0.0177
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0029 0.005
Leishmania major hypothetical protein, unknown function 0.0047 0.0073 0.1214
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0003 0.00000000031052
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0054 0.0094
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0014 0.0041
Schistosoma mansoni acetylcholine receptor subunit beta 0.0155 0.0337 0.0679
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0326 0.0754 0.1518
Brugia malayi RNA binding protein 0.0076 0.0146 0.0252
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0007 0.0008
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0089 0.0176 0.0581
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0035 0.0046 0.0633
Echinococcus multilocularis glycine receptor subunit beta 0.0326 0.0754 0.0752
Echinococcus multilocularis transient receptor potential gamma protein 0.0047 0.0073 0.007
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0218 0.0491 0.4761
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.004 0.0057 0.0238
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0182
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0179 0.036
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0029 0.0115
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0022 0.0306
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0121 0.0241
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Plasmodium falciparum acyl-CoA synthetase 0.0072 0.0135 0.9184
Brugia malayi nuclear receptor NHR-88 0.0022 0.0014 0.0024
Schistosoma mansoni hypothetical protein 0.2047 0.4953 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0035 0.0046 0.0759
Brugia malayi Melatonin receptor type 1A 0.0066 0.0121 0.0208
Echinococcus granulosus ribonuclease H1 0.0044 0.0066 0.0128
Brugia malayi Protein kinase domain containing protein 0.006 0.0107 0.0185
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0058 0.0111
Toxoplasma gondii hypothetical protein 0.0018 0.0004 0.0023
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0326 0.0754 0.1518
Echinococcus multilocularis voltage gated potassium channel 0.0047 0.0073 0.007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0123 0.0261 0.0258
Schistosoma mansoni hypothetical protein 0.0047 0.0073 0.0146
Echinococcus granulosus hyperpolarization activated cyclic 0.0047 0.0073 0.0142
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0014 0.0025
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0146 0.0482
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Schistosoma mansoni hypothetical protein 0.0125 0.0264 0.053
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0054 0.094
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0051 0.3445
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0066 0.0121 0.0118
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0057 0.0238
Leishmania major 4-coumarate:coa ligase-like protein 0.0096 0.0195 0.3765
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0007 0.0011
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0047 0.0073 0.007
Echinococcus multilocularis BC026374 protein (S09 family) 0.0209 0.0471 0.0468
Brugia malayi Papain family cysteine protease containing protein 0.0044 0.0067 0.0115
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0007 0.0011
Brugia malayi Carboxylesterase family protein 0.0209 0.0471 0.0812
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0112 0.204
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0047 0.0073 0.0146
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.014 0.0277
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0326 0.0754 0.0752
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.004 0.0057 0.0992
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.0096 0.0195 0.0644
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Schistosoma mansoni transient receptor potential channel 4 0.0047 0.0073 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Giardia lamblia NADPH oxidoreductase, putative 0.008 0.0155 1
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0007 0.0011
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0896 0.2146 0.2143
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0218 0.0491 1
Leishmania major cysteine peptidase A (CPA) 0.0044 0.0067 0.1076
Echinococcus multilocularis geminin 0.0557 0.1319 0.1316
Schistosoma mansoni DNA helicase recq5 0.0018 0.0003 0.0003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0155 0.0268
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0047 0.0073 0.007
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0047 0.0073 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Brugia malayi ORL1-like opioid receptor 0.0066 0.0121 0.0208
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0073 0.0142
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0173 0.0348
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0196 0.0337
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0326 0.0754 0.1521
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0054 0.0104
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0121 0.0238
Onchocerca volvulus 0.0326 0.0754 0.327
Onchocerca volvulus Ribonuclease H1 homolog 0.0044 0.0066 0.0269
Echinococcus granulosus 7TM GPCR rhodopsin 0.0066 0.0121 0.0238
Loa Loa (eye worm) hypothetical protein 0.0044 0.0067 0.0215
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0326 0.0754 0.0752
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0121 0.0241
Brugia malayi steroid hormone receptor 0.0022 0.0014 0.0024
Onchocerca volvulus 0.0135 0.0289 0.1241
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0103 0.7
Schistosoma mansoni vesicular amine transporter 0.0047 0.0073 0.0146
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0079 0.0076
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0007 0.0004
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0155 0.0337 0.0676
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Brugia malayi follicle stimulating hormone receptor 0.0308 0.0712 0.1228
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0155 0.0337 0.0335
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0419 0.8498
Schistosoma mansoni cpg binding protein 0.0152 0.033 0.0665
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0066 0.0121 0.0118
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0047 0.0073 0.0142
Schistosoma mansoni voltage-gated cation channel 0.0047 0.0073 0.0146
Schistosoma mansoni amine GPCR 0.0066 0.0121 0.0241
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0195 0.0336
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0015 0.0208
Brugia malayi neuropeptide F receptor 0.0066 0.0121 0.0208
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0419 0.0844
Brugia malayi Serotonin receptor 0.2392 0.5796 1
Brugia malayi hypothetical protein 0.0209 0.0471 0.0812
Leishmania major protein kinase, putative 0.006 0.0107 0.1923
Loa Loa (eye worm) hypothetical protein 0.0087 0.0172 0.0569
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0047 0.0073 0.0126
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0112 0.204
Echinococcus granulosus acetylcholinesterase 0.124 0.2985 0.6023
Loa Loa (eye worm) hypothetical protein 0.0254 0.0579 0.1933
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0121 0.0396
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Echinococcus multilocularis ryanodine receptor 44f 0.0047 0.0073 0.007
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Toxoplasma gondii cytochrome p450 superfamily protein 0.0035 0.0046 0.0678
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0022 0.0142
Toxoplasma gondii histone lysine methyltransferase SET1 0.0277 0.0635 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0326 0.0754 0.1301
Echinococcus granulosus microtubule associated protein 2 0.137 0.3302 0.6665
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0326 0.0754 0.1521
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0112 0.0971
Loa Loa (eye worm) phosphofructokinase 0.0218 0.0491 0.1639
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.0058 0.0114
Trichomonas vaginalis phosphofructokinase, putative 0.0218 0.0491 0.2132
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0054 0.094
Loa Loa (eye worm) hypothetical protein 0.124 0.2985 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0029 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0089 0.0176 0.3381
Brugia malayi Cyclic-nucleotide gated cation channel 0.0047 0.0073 0.0126
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Brugia malayi hypothetical protein 0.0019 0.0007 0.0011
Entamoeba histolytica modulator of drug activity B homolog, putative 0.002 0.0008 0.0105
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0253 0.0578 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0019
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0121 0.0241
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0014 0.0022
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0096 0.0195 0.3848
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0029 0.0408
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0015 0.0057
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0103 0.044
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0007 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0326 0.0754 0.1301
Echinococcus multilocularis nAChR subunit 0.0326 0.0754 0.0752
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Loa Loa (eye worm) voltage-dependent calcium channel 0.0047 0.0073 0.0237
Brugia malayi 6-phosphofructokinase 0.0218 0.0491 0.0848
Schistosoma mansoni nAChR subunit 0.0155 0.0337 0.0679
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0047 0.0073 0.0146
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0029 0.0278
Brugia malayi Cathepsin L-like precursor 0.0044 0.0067 0.0115
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.004 0.0057 0.0882
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0014 0.0025
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.008 0.0155 0.0663
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0218 0.0491 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.0538 0.1795
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Echinococcus multilocularis cysteine protease 0.0044 0.0067 0.0064
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0112 0.2029
Echinococcus multilocularis Niemann Pick C1 protein 0.043 0.101 0.1007
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0326 0.0754 0.1521
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0073 0.007
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0047 0.0073 0.0126
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0103 0.1591
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0121 0.0118
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0014 0.0011
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0326 0.0754 0.1518
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0029 0.189
Onchocerca volvulus 0.0209 0.0471 0.2034
Schistosoma mansoni opsin-like receptor 0.0066 0.0121 0.0241
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Echinococcus granulosus glycine receptor subunit beta 0.0326 0.0754 0.1518
Echinococcus multilocularis neuropeptide FF receptor 2 0.0066 0.0121 0.0118
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0209 0.0471 0.2042
Loa Loa (eye worm) hypothetical protein 0.0096 0.0195 0.0644
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0029 0.0408
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0047 0.0073 0.0146
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0054 0.749
Echinococcus granulosus cpg binding protein 0.0152 0.033 0.0662
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0047 0.0073 0.007
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0035 0.0046 0.0759
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0066 0.0121 0.0241
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Loa Loa (eye worm) hypothetical protein 0.0123 0.026 0.0862
Schistosoma mansoni hypothetical protein 0.0149 0.0323 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Entamoeba histolytica hypothetical protein 0.0171 0.0377 0.5416
Entamoeba histolytica hypothetical protein 0.002 0.0008 0.0105
Schistosoma mansoni neuropeptide F-like receptor 0.0066 0.0121 0.0241
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0146 0.0293
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0326 0.0754 0.1521
Echinococcus granulosus cathepsin l cysteine peptidase 0.0044 0.0067 0.0129
Mycobacterium tuberculosis Probable reductase 0.0108 0.0223 0.4446
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.002 0.0008 0.0105
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0066 0.0121 0.0238
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0014 0.0037
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.0067 0.0946
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0147 1
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypoxia-induced factor 1 0.0151 0.0328 0.1091
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0003 0.0001
Brugia malayi hypothetical protein 0.0155 0.0337 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0079 0.0157
Schistosoma mansoni amine GPCR 0.0066 0.0121 0.0241
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0047 0.0073 0.0146
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0067 0.0282
Entamoeba histolytica hypothetical protein 0.0019 0.0007 0.008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0014 0.0022
Echinococcus granulosus muscleblind protein 0.0297 0.0685 0.1379
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Loa Loa (eye worm) patched family protein 0.0018 0.0004 0.0006
Schistosoma mansoni phosphoglucomutase 0.0044 0.0066 0.0131
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Echinococcus granulosus short transient receptor potential channel 6 0.0047 0.0073 0.0142
Onchocerca volvulus 0.0044 0.0067 0.0272
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Schistosoma mansoni opsin-like receptor 0.0066 0.0121 0.0241
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0007 0.0008
Onchocerca volvulus 0.0171 0.0377 0.1623
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0015 0.0026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0088
Schistosoma mansoni neurotransmitter gated ion channel 0.0155 0.0337 0.0679
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0326 0.0754 0.1301
Mycobacterium leprae putative cytochrome p450 0.0035 0.0046 0.0759
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0044 0.0067 0.028
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0054 0.083
Schistosoma mansoni BC026374 protein (S09 family) 0.0209 0.0471 0.0949
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0035 0.0046 0.0759
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0035 0.0046 0.0759
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0029 0.005
Echinococcus granulosus 7tm_1 domain containing protein 0.0066 0.0121 0.0238
Schistosoma mansoni amine GPCR 0.0066 0.0121 0.0241
Onchocerca volvulus 0.0326 0.0754 0.327
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Loa Loa (eye worm) hypothetical protein 0.0081 0.0158 0.0522
Loa Loa (eye worm) carboxylesterase 0.124 0.2985 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0035 0.0046 0.0759
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.002 0.0269
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0253 0.5056
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0155 0.0337 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Plasmodium vivax vivapain-1 0.0023 0.0015 0.0084
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0003 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Trypanosoma cruzi cruzipain precursor, putative 0.0044 0.0067 0.1088
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Brugia malayi CHE-14 protein 0.0129 0.0275 0.0474
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Entamoeba histolytica hypothetical protein 0.0019 0.0007 0.008
Echinococcus multilocularis lamin 0.0081 0.0158 0.0155
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Schistosoma mansoni voltage-gated ion channel 0.0047 0.0073 0.0146
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Toxoplasma gondii ribonuclease HI protein 0.0044 0.0066 0.0999
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0047 0.0073 0.0301
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0035 0.0046 0.0759
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Brugia malayi larval opioid receptor 0.0066 0.0121 0.0208
Loa Loa (eye worm) hypothetical protein 0.0039 0.0055 0.0177
Schistosoma mansoni single-minded 0.0049 0.0079 0.0157
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0103 0.044
Schistosoma mansoni hypothetical protein 0.0066 0.0121 0.0241
Plasmodium falciparum cysteine proteinase falcipain 1 0.0023 0.0015 0.094
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0072 0.0135 0.9063
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0035 0.0046 0.0308
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0066 0.0121 0.0208
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0218 0.0491 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0209 0.0471 0.0945
Echinococcus multilocularis cathepsin L cysteine protease 0.0044 0.0067 0.0064
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0112 0.0221
Schistosoma mansoni myosin xvIII 0.0066 0.0121 0.0241
Onchocerca volvulus 0.0102 0.0207 0.0886
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0121 0.0396
Loa Loa (eye worm) hypothetical protein 0.0047 0.0074 0.024
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0047 0.0073 0.0146
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0103 0.044
Onchocerca volvulus 0.0029 0.0031 0.0118
Loa Loa (eye worm) CXXC zinc finger family protein 0.0144 0.031 0.1032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0029 0.0422
Echinococcus granulosus dro:myosuppressin receptor 0.0066 0.0121 0.0238
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0088 0.0288
Plasmodium vivax SET domain protein, putative 0.0123 0.0261 0.2035
Onchocerca volvulus 0.0209 0.0471 0.2034
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0223 0.4446
Onchocerca volvulus 0.0155 0.0337 0.1453
Brugia malayi hypothetical protein 0.0018 0.0004 0.0007
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0029 0.0408
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0035 0.0046 0.0759
Onchocerca volvulus 0.0028 0.0029 0.0107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Toxoplasma gondii exonuclease III APE 0.0039 0.0054 0.0816
Onchocerca volvulus 0.0326 0.0754 0.327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Schistosoma mansoni growth hormone secretagogue receptor 0.0066 0.0121 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0014 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Brugia malayi cytochrome P450 0.0035 0.0046 0.0079
Echinococcus multilocularis expressed conserved protein 0.0283 0.065 0.0647
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0066 0.0121 0.0241
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0074 0.0144
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0066 0.0121 0.0396
Schistosoma mansoni cpg binding protein 0.0152 0.033 0.0665
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0126 0.2418
Echinococcus granulosus dual specificity protein kinase clk2 0.006 0.0107 0.0211
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0047 0.0073 0.0126
Loa Loa (eye worm) patched family protein 0.0018 0.0004 0.0006
Brugia malayi Cation transporter family protein 0.0326 0.0754 0.1301
Trichomonas vaginalis DNA helicase recq1, putative 0.0043 0.0064 0.0269
Echinococcus multilocularis sodium leak channel non selective protein 0.0047 0.0073 0.007
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0107 0.0456
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0112 0.7201
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0326 0.0754 0.0752
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0029 0.0408
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0073 0.0142
Brugia malayi sulfakinin receptor protein 0.0066 0.0121 0.0208
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0326 0.0754 0.1301
Brugia malayi Pre-SET motif family protein 0.0123 0.0261 0.045
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0035 0.0046 0.0759
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0047 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0014 0.0024
Echinococcus multilocularis musashi 0.0081 0.0158 0.0155
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.0539 0.1082
Leishmania major cytochrome p450-like protein 0.0035 0.0046 0.0633
Schistosoma mansoni hypothetical protein 0.0557 0.1319 0.2661
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0074 0.0071
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0066 0.0121 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0107 0.0214
Loa Loa (eye worm) ctsf protein 0.0044 0.0067 0.0215
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0047 0.0073 0.0126
Trichomonas vaginalis phosphofructokinase, putative 0.0218 0.0491 0.2132
Brugia malayi PXA domain containing protein 0.0019 0.0007 0.0011
Loa Loa (eye worm) 6-phosphofructokinase 0.0218 0.0491 0.1639
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0121 0.0238
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0485
Trichomonas vaginalis replication factor C large subunit, putative 0.004 0.0057 0.0238
Brugia malayi photoreceptor-specific nuclear receptor 0.0254 0.0579 0.0999
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0209 0.0471 0.9573
Schistosoma mansoni hypothetical protein 0.0048 0.0078 0.0155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0047 0.0073 0.007
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0326 0.0754 0.0752
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0135
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0044 0.0067 0.4489
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Loa Loa (eye worm) histone methyltransferase 0.0049 0.0079 0.0256
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0047 0.0073 0.0146
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0326 0.0754 0.1301
Brugia malayi putative neuropeptide receptor 0.0066 0.0121 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.001 0.0018
Brugia malayi hypothetical protein 0.0155 0.0337 0.0582
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Brugia malayi topoisomerase 0.004 0.0057 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0035 0.0046 0.0759
Echinococcus multilocularis dro:myosuppressin receptor 0.0066 0.0121 0.0118
Loa Loa (eye worm) acetylcholine receptor protein 0.0155 0.0337 0.1123
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0014 0.0024
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0209 0.0471 0.0468
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0419 0.8498
Loa Loa (eye worm) hypothetical protein 0.0123 0.0261 0.0866
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0073 0.0142
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0047 0.0073 0.0142
Echinococcus granulosus biogenic amine 5HT receptor 0.0066 0.0121 0.0238
Schistosoma mansoni calcium-activated potassium channel 0.0047 0.0073 0.0146
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0047 0.0073 0.0237
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Onchocerca volvulus 0.004 0.0057 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Onchocerca volvulus 0.0066 0.0121 0.0507
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0146 0.0252
Loa Loa (eye worm) hypothetical protein 0.0297 0.0685 0.229
Entamoeba histolytica hypothetical protein 0.0149 0.0323 0.465
Loa Loa (eye worm) LGC-31 protein 0.0326 0.0754 0.2521
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0129 0.0275 0.1188
Loa Loa (eye worm) hypothetical protein 0.0305 0.0705 0.2356
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0014 0.0011
Onchocerca volvulus 0.0066 0.0121 0.0507
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0121 0.0118
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0035 0.0046 0.0759
Plasmodium vivax vivapain-3 0.0023 0.0015 0.0084
Brugia malayi hypoxia-induced factor 1 0.0151 0.0328 0.0566
Onchocerca volvulus 0.0044 0.0067 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0014 0.0024
Echinococcus granulosus sex peptide receptor 0.0066 0.0121 0.0238
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0112 0.204
Brugia malayi Tachykinin-like peptides receptor 99D 0.0066 0.0121 0.0208
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0223 0.4446
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0014 0.0025
Onchocerca volvulus 0.0066 0.0121 0.0507
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0029 0.0408
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0261 0.0525
Schistosoma mansoni biogenic amine receptor 0.0066 0.0121 0.0241
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0171 0.0377 0.065
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.001 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0019
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0029 0.0408
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0088 0.0288
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Brugia malayi voltage-dependent calcium channel 0.0047 0.0073 0.0126
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Onchocerca volvulus 0.0096 0.0195 0.083
Giardia lamblia Replication factor C, subunit 1 0.004 0.0057 0.3563
Brugia malayi Cation transporter family protein 0.0326 0.0754 0.1301
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0179 0.036
Schistosoma mansoni 60S ribosomal protein L21 0.0047 0.0073 0.0146
Loa Loa (eye worm) CHromoDomain protein family member 0.002 0.0008 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0057 0.0238
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0112 0.0478
Giardia lamblia NADPH oxidoreductase, putative 0.008 0.0155 1
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0015 0.0198
Loa Loa (eye worm) hypothetical protein 0.0072 0.0135 0.0445
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Echinococcus multilocularis two pore calcium channel protein 1 0.0047 0.0073 0.007
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Plasmodium vivax replication factor C subunit 1, putative 0.004 0.0057 0.0417
Echinococcus granulosus cathepsin L cysteine proteinase 0.0044 0.0067 0.0129
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Brugia malayi Patched related family protein 4 0.0018 0.0004 0.0007
Echinococcus granulosus ryanodine receptor 44f 0.0047 0.0073 0.0142
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0088 0.0736
Schistosoma mansoni cathepsin F (C01 family) 0.0044 0.0067 0.0132
Entamoeba histolytica cysteine proteinase 2 0.0023 0.0015 0.0198
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0088
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Plasmodium vivax vivapain-2 0.0044 0.0067 0.0495
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0007 0.0004
Brugia malayi hypothetical protein 0.0305 0.0705 0.1216
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.002 0.0008 0.0026
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0044 0.0067 0.0215
Echinococcus multilocularis cysteine protease 0.0044 0.0067 0.0064
Schistosoma mansoni hypothetical protein 0.0035 0.0046 0.009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0014 0.0024
Echinococcus granulosus transient receptor potential gamma protein 0.0047 0.0073 0.0142
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0007 0.0013
Echinococcus multilocularis conserved hypothetical protein 0.0047 0.0073 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0014 0.0011
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0007 0.0013
Onchocerca volvulus 0.0958 0.2298 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0155 0.0153
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0223 0.4446
Echinococcus granulosus neuroligin 0.0209 0.0471 0.0945
Schistosoma mansoni neurotransmitter gated ion channel 0.0171 0.0377 0.0758
Loa Loa (eye worm) hypothetical protein 0.0297 0.0685 0.229
Brugia malayi hypothetical protein 0.0164 0.0359 0.0619
Echinococcus granulosus neuropeptide receptor 0.0066 0.0121 0.0238
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0047 0.0073 0.007
Toxoplasma gondii patched family protein 0.0018 0.0004 0.0023
Echinococcus granulosus acetylcholinesterase 0.124 0.2985 0.6023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0067 0.0282
Brugia malayi intermediate filament protein 0.0081 0.0158 0.0273
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0155 0.0337 0.0676
Echinococcus granulosus cathepsin L 0.0023 0.0015 0.0024
Entamoeba histolytica cysteine proteinase 1, putative 0.0023 0.0015 0.0198
Echinococcus granulosus replication factor c subunit 1 0.004 0.0057 0.0109
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0088 0.1546
Echinococcus granulosus neuropeptides capa receptor 0.0066 0.0121 0.0238
Brugia malayi hypothetical protein 0.0149 0.0323 0.0558
Echinococcus multilocularis neuropeptide receptor A26 0.0551 0.1303 0.1301
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0047 0.0073 0.007
Onchocerca volvulus 0.0028 0.0029 0.0107
Schistosoma mansoni lamin 0.0081 0.0158 0.0317
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0147 0.0254
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Toxoplasma gondii patched family protein 0.0018 0.0004 0.0023
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0029 0.0291
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0146 0.0293
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.006 0.0107 0.1935
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0029 0.0408
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0173 0.0345
Echinococcus multilocularis allatostatin A receptor 0.0066 0.0121 0.0118
Leishmania major cytochrome p450-like protein 0.0035 0.0046 0.0633
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0326 0.0754 0.1301
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0103 0.044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0007 0.0008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0047 0.0073 0.0146
Schistosoma mansoni adenoreceptor 0.0066 0.0121 0.0241
Echinococcus multilocularis acetylcholinesterase 0.124 0.2985 0.2983
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0196 0.0393
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0035 0.0046 0.0759
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0014 0.0011
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Onchocerca volvulus 0.0326 0.0754 0.327
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Loa Loa (eye worm) neuropeptide F receptor 0.0066 0.0121 0.0396
Echinococcus multilocularis shaker cognate 0.0047 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Brugia malayi hypothetical protein 0.0155 0.0337 0.0582
Onchocerca volvulus 0.0066 0.0121 0.0507
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.002 0.1283
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0096
Brugia malayi DKFZp564C0469 protein 0.004 0.0057 0.0098
Schistosoma mansoni intermediate filament proteins 0.0081 0.0158 0.0317
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0103 0.0786
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Loa Loa (eye worm) ion channel NompC 0.0047 0.0073 0.0237
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0021 0.004
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus multilocularis carboxylesterase 5A 0.124 0.2985 0.2983
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.001 0.0018
Onchocerca volvulus 0.0066 0.0121 0.0507
Schistosoma mansoni alpha-1 adrenergic receptor 0.0066 0.0121 0.0241
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0029 0.0408
Mycobacterium ulcerans 6-phosphofructokinase 0.0218 0.0491 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0073 0.007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0196 0.0193
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0047 0.0073 0.0126
Mycobacterium ulcerans carboxylesterase, LipT 0.0209 0.0471 0.9573
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0044 0.0066 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0096 0.0195 0.3848
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0066 0.0121 0.0118
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0047 0.0073 0.0142
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0196 0.0389
Echinococcus multilocularis replication factor c subunit 1 0.004 0.0057 0.0054
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0066 0.0121 0.0241
Onchocerca volvulus 0.0155 0.0337 0.1453
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0007 0.0011
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0047 0.0073 0.0237
Brugia malayi Protein kinase domain containing protein 0.0089 0.0176 0.0304
Toxoplasma gondii transporter, cation channel family protein 0.0047 0.0073 0.1115
Echinococcus granulosus lamin 0.0081 0.0158 0.0314
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0035 0.0046 0.0759
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0121 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0165
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0014 0.0011
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0066 0.0121 0.0118
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0029 0.0408
Echinococcus granulosus hypothetical protein 0.0047 0.0073 0.0142
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0007 0.0008
Trichomonas vaginalis DNA helicase recq, putative 0.0043 0.0064 0.0269
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Brugia malayi hypothetical protein 0.0155 0.0337 0.0582
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0188 0.0419 0.8498
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0029 0.0408
Echinococcus granulosus geminin 0.0557 0.1319 0.2658
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0326 0.0754 0.0752
Echinococcus multilocularis glycine receptor subunit beta 0.0326 0.0754 0.0752
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Loa Loa (eye worm) fibroinase 0.0044 0.0067 0.0215
Echinococcus granulosus allatostatin A receptor 0.0066 0.0121 0.0238
Echinococcus granulosus sterol regulatory element binding protein 0.0129 0.0275 0.055
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0073 0.0142
Echinococcus multilocularis g protein coupled receptor 0.0066 0.0121 0.0118
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0842 0.2014 0.6745
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0047 0.0073 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0067 0.0282
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0067 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0014 0.0024
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0155 0.0337 0.0582
Brugia malayi Cathepsin L-like precursor 0.0029 0.0031 0.0054
Echinococcus multilocularis two pore calcium channel protein 2 0.0047 0.0073 0.007
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0047 0.0073 0.0126
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0015 0.0007
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0326 0.0754 0.0752
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0326 0.0754 0.1521
Brugia malayi phosphofructokinase 0.0218 0.0491 0.0848
Onchocerca volvulus Cathepsin L homolog 0.0044 0.0067 0.0272
Onchocerca volvulus Huntingtin homolog 0.0123 0.026 0.1113
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0173 0.0299
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0031 0.0061
Echinococcus granulosus lamin dm0 0.0081 0.0158 0.0314
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0029 0.0408
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0035 0.0046 0.0759
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0147 0.2864
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0014 0.0041
Brugia malayi nuclear hormone receptor 0.0022 0.0014 0.0024
Schistosoma mansoni hypothetical protein 0.0066 0.0121 0.0241
Echinococcus granulosus cysteine protease 0.0023 0.0015 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0007 0.0011
Echinococcus multilocularis lamin dm0 0.0081 0.0158 0.0155
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Brugia malayi hypothetical protein 0.0155 0.0337 0.0582
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0196 0.0393
Loa Loa (eye worm) hypothetical protein 0.0814 0.1945 0.6515
Brugia malayi Cathepsin L-like precursor 0.0044 0.0067 0.0115
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Schistosoma mansoni histamine h1 receptor 0.0066 0.0121 0.0241
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0073 0.0142
Echinococcus granulosus nibrin 0.004 0.0057 0.0109
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0055 0.0106
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus serotonin receptor 0.0066 0.0121 0.0238
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0047 0.0073 0.0584
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Echinococcus granulosus cathepsin l1 0.0029 0.0031 0.0058
Chlamydia trachomatis DNA ligase 0.004 0.0057 0.2908
Schistosoma mansoni hypothetical protein 0.008 0.0155 0.0311
Loa Loa (eye worm) TYRA-2 protein 0.0066 0.0121 0.0396
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.0539 0.0536
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.006 0.0107 0.1649
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0171 0.0377 0.0758
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0007 0.0004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0155 0.0308
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0253 0.0578 0.1929
Echinococcus granulosus neuropeptide s receptor 0.0551 0.1303 0.2627
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0014 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Toxoplasma gondii patched family protein 0.0018 0.0004 0.0023
Mycobacterium leprae Conserved hypothetical protein 0.0035 0.0046 0.0759
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0253 0.5056
Schistosoma mansoni phosphoglucomutase 0.0044 0.0066 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0171 0.0377 0.065
Echinococcus multilocularis G-protein coupled receptor, putative 0.0066 0.0121 0.0118
Entamoeba histolytica hypothetical protein 0.0149 0.0323 0.465
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Loa Loa (eye worm) ACC-1 protein 0.0326 0.0754 0.2521
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Onchocerca volvulus 0.0102 0.0207 0.0886
Loa Loa (eye worm) hypothetical protein 0.0072 0.0135 0.0445
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0969 0.2323 0.4008
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.008 0.0155 0.0663
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0155 0.0308
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Echinococcus granulosus sodium leak channel non selective protein 0.0047 0.0073 0.0142
Echinococcus granulosus cathepsin L cysteine protease 0.0023 0.0015 0.0024
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0029 0.0291
Echinococcus multilocularis protein dispatched 1 0.0147 0.032 0.0317
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0066 0.0121 0.0396
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0121 0.0238
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0112 0.204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Schistosoma mansoni cytochrome P450 0.0035 0.0046 0.009
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.004 0.0057 0.0238
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0053 0.009 0.075
Echinococcus granulosus Niemann Pick C1 protein 0.0301 0.0694 0.1397
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0146 0.0293
Leishmania major hypothetical protein, conserved 0.0026 0.0022 0.014
Brugia malayi MH2 domain containing protein 0.0237 0.0538 0.0928
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.002 0.0224
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Brugia malayi Cytochrome P450 family protein 0.0035 0.0046 0.0079
Schistosoma mansoni hypothetical protein 0.0125 0.0264 0.053
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0146 0.0144
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.002 0.0091
Loa Loa (eye worm) G-protein coupled receptor 0.0066 0.0121 0.0396
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0007 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0078 0.0134
Brugia malayi Cytochrome P450 family protein 0.0053 0.0088 0.0153
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0066 0.0121 0.0396
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0261 0.0525
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0326 0.0754 0.1301
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0007 0.0004
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0047 0.0073 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0015 0.0054
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0121 0.0118
Brugia malayi latrophilin 2 splice variant baaae 0.0173 0.0382 0.0659
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0029 0.0398
Brugia malayi Carboxylesterase family protein 0.124 0.2985 0.5149
Echinococcus multilocularis short transient receptor potential channel 6 0.0047 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0073 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0195 0.3848
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0326 0.0754 0.1301
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.002 0.0224
Mycobacterium ulcerans endonuclease IV 0.0077 0.0147 0.2864
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0003 0.0005
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0326 0.0754 0.1518
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0048 0.0045
Echinococcus granulosus two pore calcium channel protein 2 0.0047 0.0073 0.0142
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0029 0.005
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Onchocerca volvulus 0.0081 0.0158 0.0671
Schistosoma mansoni hypothetical protein 0.0125 0.0264 0.053
Toxoplasma gondii transporter, cation channel family protein 0.0047 0.0073 0.1115
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Echinococcus multilocularis voltage dependent calcium channel 0.0047 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0301 0.0694 1
Trichomonas vaginalis FMN-dependent NADH-azoreductase, putative 0.002 0.0008 0.0026
Echinococcus multilocularis 6 phosphofructokinase 0.0218 0.0491 0.0489
Schistosoma mansoni topbp1 0.004 0.0057 0.0113
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0146 0.0293
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0326 0.0754 0.1301
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0035 0.0046 0.0759
Brugia malayi RNase H family protein 0.0044 0.0066 0.0114
Brugia malayi hypothetical protein 0.0047 0.0073 0.0126
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.002 0.0008 0.0005
Echinococcus multilocularis sex peptide receptor 0.0066 0.0121 0.0118
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0158 0.0522
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0223 0.4446
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0188 0.0419 0.0841
Schistosoma mansoni cathepsin F (C01 family) 0.0044 0.0067 0.0132
Brugia malayi F/Y-rich N-terminus family protein 0.0048 0.0078 0.0134
Schistosoma mansoni 6-phosphofructokinase 0.0218 0.0491 0.099
Plasmodium falciparum thioredoxin reductase 0.0047 0.0075 0.5083
Schistosoma mansoni neuropeptide receptor 0.0066 0.0121 0.0241
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0155 0.0512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Echinococcus multilocularis transfer RNA-Gly 0.0047 0.0073 0.007
Toxoplasma gondii cathepsin CPL 0.0044 0.0067 0.1011
Onchocerca volvulus 0.0155 0.0337 0.1453
Onchocerca volvulus 0.0066 0.0121 0.0507
Echinococcus multilocularis bloom syndrome protein 0.0043 0.0064 0.0061
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.002 0.0008 0.0026
Brugia malayi M-phase phosphoprotein, mpp8 0.0102 0.0207 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0029 0.005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0054 0.0174
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis neuropeptide s receptor 0.0551 0.1303 0.1301
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0067 0.0282
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0014 0.0024
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.0261 0.0521
Echinococcus multilocularis sterol regulatory element binding protein 0.0129 0.0275 0.0272
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0155 0.0337 0.1123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0067 0.0282
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0014 0.0022
Echinococcus granulosus G protein coupled receptor 139 0.0066 0.0121 0.0238
Schistosoma mansoni transcription factor LCR-F1 0.0149 0.0323 0.0651
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0047 0.0073 0.0142
Echinococcus granulosus glycine receptor subunit alpha 1 0.0326 0.0754 0.1518
Brugia malayi protein C24B5.3 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0075 0.0147
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0066 0.0121 0.0118
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Brugia malayi Transient-receptor-potential like protein 0.0047 0.0073 0.0126
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0014 0.0025
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0171 0.0377 0.0758
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.014 0.0137
Brugia malayi Dopamine receptor protein 2 0.0066 0.0121 0.0208
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0123 0.0261 0.4085
Echinococcus granulosus voltage dependent calcium channel 0.0047 0.0073 0.0142
Brugia malayi hypothetical protein 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0129 0.0275 0.0913
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.004 0.0057 0.042
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Echinococcus granulosus carboxylesterase 5A 0.124 0.2985 0.6023
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0066 0.0121 0.0238
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0014 0.0041
Loa Loa (eye worm) acetylcholinesterase 1 0.124 0.2985 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Brugia malayi cation channel family protein 0.0047 0.0073 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0057 0.0238
Brugia malayi Dopamine receptor protein 1 0.0066 0.0121 0.0208
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0047 0.0073 0.007
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Schistosoma mansoni neuropeptide receptor 0.0066 0.0121 0.0241
Mycobacterium ulcerans aldehyde dehydrogenase 0.0188 0.0419 0.8498
Brugia malayi olfactory channel protein osm-9 0.0047 0.0074 0.0128
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0047 0.0073 0.0126
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0073 0.0142
Schistosoma mansoni biogenic amine receptor 0.0066 0.0121 0.0241
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0007 0.0004
Brugia malayi hypothetical protein 0.0102 0.0208 0.0359
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0014 0.0037
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0014 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0123 0.026 0.0862
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0014 0.0011
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Schistosoma mansoni voltage-dependent calcium channel 0.0047 0.0073 0.0146
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Loa Loa (eye worm) cysteine protease 0.0044 0.0067 0.0215
Echinococcus multilocularis sodium channel protein 0.0047 0.0073 0.007
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0158 0.0273
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0103 0.6628
Brugia malayi Bloom's syndrome protein homolog 0.0043 0.0064 0.0111
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0047 0.0073 0.0126
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Entamoeba histolytica protein kinase, putative 0.0089 0.0176 0.2522
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0007 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.003 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0326 0.0754 0.0752
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0326 0.0754 0.2521
Mycobacterium leprae conserved hypothetical protein 0.0025 0.002 0.0224
Onchocerca volvulus 0.0066 0.0121 0.0507
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0057 0.0882
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0146 0.0293
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0029 0.0088
Treponema pallidum DNA ligase (lig) 0.004 0.0057 0.0785
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0121 0.0238
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0326 0.0754 0.1301
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Loa Loa (eye worm) ryanodine receptor 0.0047 0.0073 0.0237
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0029 0.0052
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0073 0.0309
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0075 0.0244
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0089 0.0176 0.161
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0007 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0196 0.0193
Loa Loa (eye worm) hypothetical protein 0.0072 0.0135 0.0445
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0014 0.0025
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0158 0.0522
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.0261 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0007 0.0011
Schistosoma mansoni gliotactin 0.0209 0.0471 0.0949
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0326 0.0754 0.1518
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Brugia malayi glutathione reductase 0.0047 0.0075 0.013
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Loa Loa (eye worm) calcium channel 0.0047 0.0073 0.0237
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0014 0.0025
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0035 0.0046 0.0759
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0029 0.005
Echinococcus granulosus orexin receptor type 2 0.0066 0.0121 0.0238
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0046 0.0647
Leishmania major protein kinase, putative 0.006 0.0107 0.1923
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Leishmania major ribonuclease H1, putative 0.0044 0.0066 0.106
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0326 0.0754 0.1301
Loa Loa (eye worm) cytochrome P450 family protein 0.0111 0.023 0.0763
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0035 0.0046 0.0759
Echinococcus granulosus tm gpcr rhodopsin 0.0066 0.0121 0.0238
Schistosoma mansoni hypothetical protein 0.0125 0.0264 0.053
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0044 0.0067 0.0064
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0022 0.0073
Loa Loa (eye worm) hypothetical protein 0.124 0.2985 1
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0107 0.0214
Brugia malayi neuropeptide F receptor 0.0066 0.0121 0.0208
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0196 0.0389
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0121 0.0118
Leishmania major cytochrome p450-like protein 0.0053 0.0088 0.1534
Echinococcus granulosus hypothetical protein 0.0059 0.0103 0.0203
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Onchocerca volvulus Cathepsin L homolog 0.0044 0.0067 0.0272
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.006 0.0107 0.1935
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0112 0.0221
Schistosoma mansoni amine GPCR 0.0066 0.0121 0.0241
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0072 0.0135 0.2617
Echinococcus granulosus alpha 1A adrenergic receptor 0.0066 0.0121 0.0238
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0195 0.0336
Onchocerca volvulus Neuropeptide F receptor homolog 0.0066 0.0121 0.0507
Brugia malayi RNase H family protein 0.0044 0.0066 0.0114
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0112 0.0478
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Onchocerca volvulus 0.0066 0.0121 0.0507
Schistosoma mansoni coup transcription factor 0.0022 0.0014 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0047 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Loa Loa (eye worm) hypothetical protein 0.0969 0.2323 0.7782
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0054 0.3646
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0096
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0029 0.0115
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0182
Loa Loa (eye worm) hypothetical protein 0.0102 0.0207 0.0687
Echinococcus granulosus nAChR subunit 0.0171 0.0377 0.0755
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0075 0.127
Brugia malayi hypothetical protein 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Onchocerca volvulus 0.0044 0.0067 0.0272
Trypanosoma brucei ribonuclease H1 0.0044 0.0066 0.0511
Leishmania major ATP-dependent phosphofructokinase 0.0218 0.0491 1
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0121 0.0118
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0026 0.0022 0.0066
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0022 0.144
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0007 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0035 0.0046 0.0759
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0015 0.0198
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0066 0.0121 0.0241
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0029 0.0408
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0326 0.0754 0.2521
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0253 0.5056
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Loa Loa (eye worm) patched family protein 0.0018 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0557 0.1319 0.2661
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Echinococcus granulosus dual specificity 0.0089 0.0176 0.035
Brugia malayi MAP kinase sur-1 0.0062 0.0112 0.0193
Schistosoma mansoni hypothetical protein 0.008 0.0155 0.0311
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.004 0.0057 0.0805
Echinococcus multilocularis neuropeptide Y receptor 0.0066 0.0121 0.0118
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Toxoplasma gondii aldehyde dehydrogenase 0.0188 0.0419 0.6586
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0112 0.0224
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0029 0.0408
Echinococcus granulosus g-protein coupled receptor 0.0066 0.0121 0.0238
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0188 0.0419 0.0416
Brugia malayi Patched protein homolog 1 0.0018 0.0004 0.0007
Loa Loa (eye worm) oxidoreductase 0.0028 0.0029 0.0088
Schistosoma mansoni nAChR subunit 0.0155 0.0337 0.0679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0121 0.0118
Entamoeba histolytica phosphofructokinase, putative 0.0218 0.0491 0.7073
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0149 0.0323 0.0648
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Brugia malayi hypothetical protein 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Trichomonas vaginalis set domain proteins, putative 0.0958 0.2297 1
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.004 0.0057 0.8035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0029 0.0408
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0029 0.0408
Onchocerca volvulus 0.0066 0.0121 0.0507
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0044 0.0067 0.0215
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0067 0.1088
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0066 0.0121 0.0118
Entamoeba histolytica hypothetical protein 0.0025 0.002 0.027
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis orexin receptor type 2 0.0066 0.0121 0.0118
Echinococcus granulosus g protein coupled receptor 0.0066 0.0121 0.0238
Schistosoma mansoni phosphoglucomutase 0.0044 0.0066 0.0131
Echinococcus granulosus sodium channel protein 0.0047 0.0073 0.0142
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Echinococcus multilocularis g-protein coupled receptor 0.0066 0.0121 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Onchocerca volvulus 0.0022 0.0014 0.0041
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.001 0.0025
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Onchocerca volvulus 0.0088 0.0173 0.0738
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Trypanosoma brucei ingi protein (ORF1) 0.0053 0.009 0.075
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0054 0.083
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0014 0.0011
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0066 0.0121 0.0208
Loa Loa (eye worm) RecQ helicase 0.0043 0.0064 0.0206
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.006 0.0107 0.1935
Echinococcus granulosus glycine receptor subunit alpha 1 0.0326 0.0754 0.1518
Onchocerca volvulus 0.0171 0.0377 0.1623
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0029 0.0408
Echinococcus granulosus glycine receptor subunit alpha 1 0.0326 0.0754 0.1518
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0047 0.0073 0.0126
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0075 0.0564
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0103 0.044
Schistosoma mansoni transient receptor potential channel 0.0047 0.0074 0.0148
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0196 0.0647
Loa Loa (eye worm) hypothetical protein 0.0072 0.0135 0.0445
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0047 0.0073 0.0142
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0007 0.0011
Entamoeba histolytica hypothetical protein 0.0149 0.0323 0.465
Echinococcus granulosus dnaJ subfamily B 0.2047 0.4953 1
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Echinococcus multilocularis neuropeptide receptor 0.0066 0.0121 0.0118
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0073 0.0146
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0066 0.0121 0.0241
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0096 0.0195 0.3848
Brugia malayi Cytochrome P450 family protein 0.0111 0.023 0.0397
Brugia malayi Pax transcription activation domain interacting protein 0.004 0.0057 0.0098
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0015 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0088 0.0288
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0326 0.0754 0.2521
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0029 0.0088
Loa Loa (eye worm) melatonin receptor type 1A 0.0066 0.0121 0.0396
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0019 0.0209
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0029 0.0408
Brugia malayi Cathepsin L-like precursor 0.0044 0.0067 0.0115
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0013
Toxoplasma gondii transporter, cation channel family protein 0.0047 0.0073 0.1115
Echinococcus multilocularis short transient receptor potential channel 6 0.0047 0.0073 0.007
Mycobacterium ulcerans hypothetical protein 0.0096 0.0195 0.3848
Brugia malayi AMP-binding enzyme family protein 0.0096 0.0195 0.0336
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0326 0.0754 0.0752
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0066 0.0121 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0112 0.2029
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0067 0.1088
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0015 0.0014
Entamoeba histolytica hypothetical protein 0.0089 0.0176 0.2522
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0073 0.007
Plasmodium vivax vivapain-2 0.0044 0.0067 0.0495
Onchocerca volvulus 0.0048 0.0078 0.0321
Echinococcus granulosus shaker cognate 0.0047 0.0073 0.0142
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0007 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.001 0.0018
Brugia malayi G-protein coupled receptor 0.0066 0.0121 0.0208
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus multilocularis voltage dependent calcium channel 0.0047 0.0073 0.007
Schistosoma mansoni survival motor neuron protein 0.0048 0.0078 0.0155
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0326 0.0754 0.1301
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Brugia malayi CHD4 protein 0.002 0.0008 0.0013
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Toxoplasma gondii endonuclease IV APN 0.0077 0.0147 0.2285
Entamoeba histolytica acyl-coA synthetase, putative 0.0096 0.0195 0.2792
Loa Loa (eye worm) carboxylesterase 0.0209 0.0471 0.157
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0121 0.0118
Loa Loa (eye worm) hypothetical protein 0.008 0.0154 0.051
Loa Loa (eye worm) ACC-1 protein 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0007 0.0004
Brugia malayi Carboxylesterase family protein 0.0209 0.0471 0.0812
Echinococcus granulosus nAChR subunit 0.0326 0.0754 0.1518
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0044 0.0067 0.0064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0066 0.0213
Entamoeba histolytica cysteine protease, putative 0.0023 0.0015 0.0198
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0047 0.0073 0.0142
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Echinococcus multilocularis microtubule associated protein 2 0.137 0.3302 0.33
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0176 0.0353
Onchocerca volvulus 0.0066 0.0121 0.0507
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0066 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.001 0.0015
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0029 0.041
Trypanosoma cruzi ribonuclease H1, putative 0.0044 0.0066 0.1072
Brugia malayi Calcitonin receptor-like protein seb-1 0.0253 0.0578 0.0997
Loa Loa (eye worm) hypothetical protein 0.0301 0.0694 0.232
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0066 0.0121 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0057 0.0238
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0326 0.0754 0.2521
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.002 0.0269
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0035 0.0046 0.0759
Echinococcus granulosus single minded 2 0.0036 0.0048 0.0091
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0096
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.002 0.0008 0.001
Brugia malayi RNase H family protein 0.0044 0.0066 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0029 0.0291
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.0195 0.2792
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0326 0.0754 0.1518
Brugia malayi Thioredoxin reductase 0.0047 0.0075 0.013
Echinococcus multilocularis dual specificity 0.0089 0.0176 0.0173
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0209 0.0471 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0106 0.0451
Schistosoma mansoni ryanodine receptor related 0.0047 0.0073 0.0146
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0112 0.1729
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0047 0.0073 0.1226
Echinococcus granulosus somatostatin receptor 0.0066 0.0121 0.0238
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0014 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.0896 0.2146 0.4329
Schistosoma mansoni transient receptor potential channel 0.0047 0.0073 0.0146
Schistosoma mansoni acetylcholinesterase 0.0209 0.0471 0.0949
Toxoplasma gondii patched family protein 0.0018 0.0004 0.0023
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Onchocerca volvulus 0.0066 0.0121 0.0507
Brugia malayi excitatory GABA receptor EXP-1A 0.0326 0.0754 0.1301
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Toxoplasma gondii thioredoxin reductase 0.0047 0.0075 0.1148
Brugia malayi putative neuropeptide receptor NPR1 0.0066 0.0121 0.0208
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Echinococcus multilocularis muscleblind protein 1 0.0297 0.0685 0.0683
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0014 0.0022
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0047 0.0073 0.0146
Schistosoma mansoni cpg binding protein 0.0144 0.031 0.0624
Trypanosoma cruzi cysteine peptidase, putative 0.0044 0.0067 0.1088
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0015 0.0028
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0326 0.0754 0.1518
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0326 0.0754 0.1521
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Loa Loa (eye worm) cytochrome P450 0.0035 0.0046 0.0144
Brugia malayi protein C24B5.3 0.0018 0.0004 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Schistosoma mansoni neurotransmitter gated ion channel 0.0155 0.0337 0.0679
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0103 0.6558
Onchocerca volvulus 0.0209 0.0471 0.2034
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0014 0.0011
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.004 0.0057 0.0098
Brugia malayi Cytochrome P450 family protein 0.0053 0.0088 0.0153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Entamoeba histolytica hypothetical protein 0.0019 0.0007 0.008
Onchocerca volvulus 0.0044 0.0067 0.0272
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0015 0.0054
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0047 0.0073 0.0146
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0103 0.1591
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0047 0.0073 0.007
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0007 0.0011
Schistosoma mansoni opsin-like receptor 0.0066 0.0121 0.0241
Onchocerca volvulus 0.0066 0.0121 0.0507
Brugia malayi cation channel family protein 0.0047 0.0073 0.0126
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0073 0.0142
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0047 0.0073 0.0142
Onchocerca volvulus 0.0047 0.0073 0.0301
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0022 0.144
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.0176 0.2522
Onchocerca volvulus 0.0326 0.0754 0.327
Echinococcus multilocularis fmrfamide receptor 0.0066 0.0121 0.0118
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0054 0.0732
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0044 0.0067 0.0282
Onchocerca volvulus 0.0044 0.0067 0.0272
Echinococcus multilocularis nAChR subunit 0.0171 0.0377 0.0374
Schistosoma mansoni topbp1 0.004 0.0057 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Loa Loa (eye worm) hypothetical protein 0.0096 0.0195 0.0644
Schistosoma mansoni hypothetical protein 0.0066 0.0121 0.0241
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0054 0.0768
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0035 0.0046 0.0759
Echinococcus multilocularis neuroligin 0.0209 0.0471 0.0468
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0066 0.0121 0.0118
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0057 0.0882
Mycobacterium tuberculosis Carboxylesterase LipT 0.0209 0.0471 0.9573
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0057 0.0238
Brugia malayi hypothetical protein 0.0123 0.026 0.0448
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0209 0.0471 0.9573
Loa Loa (eye worm) hypothetical protein 0.0933 0.2236 0.7489
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0089 0.0176 0.3381
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0014 0.0024
Loa Loa (eye worm) hypothetical protein 0.0059 0.0103 0.0338
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0015 0.0028
Trichomonas vaginalis spcc417.12 protein, putative 0.0209 0.0471 0.2042
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0047 0.0073 0.1214
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0126 0.2418
Entamoeba histolytica cysteine proteinase, putative 0.0044 0.0067 0.0946
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0066 0.0121 0.0396
Echinococcus granulosus peptide allatostatin:somatostatin 0.0066 0.0121 0.0238
Brugia malayi Muscleblind-like protein 0.0297 0.0685 0.1183
Echinococcus granulosus TRP transient receptor potential channel 0.0047 0.0073 0.0142
Echinococcus granulosus cytochrome P450 2K1 0.0035 0.0046 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0058 0.0055
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0029 0.041
Schistosoma mansoni patched 1 0.0129 0.0275 0.0553
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0112 0.0367
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0054 0.0227
Brugia malayi Cathepsin L-like cysteine proteinase 0.0029 0.0031 0.0054
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0066 0.0121 0.0507
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.006 0.0107 0.0921
Onchocerca volvulus 0.0028 0.0029 0.0107
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0103 0.1475
Loa Loa (eye worm) hypothetical protein 0.0102 0.0208 0.069
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0035 0.0046 0.0647
Loa Loa (eye worm) carboxylesterase 0.0209 0.0471 0.157
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Brugia malayi RE15519p 0.0066 0.0121 0.0208
Brugia malayi Cathepsin L-like precursor 0.0029 0.0031 0.0054
Schistosoma mansoni microtubule-associated protein tau 0.137 0.3302 0.6666
Echinococcus granulosus Niemann Pick C1 protein 0.043 0.101 0.2034
Schistosoma mansoni biogenic amine (5HT) receptor 0.0066 0.0121 0.0241
Echinococcus multilocularis voltage gated potassium channel 0.0047 0.0073 0.007
Trypanosoma brucei protein kinase, putative 0.0062 0.0112 0.0971
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0003 0.0005
Onchocerca volvulus Cathepsin F homolog 0.0044 0.0067 0.0272
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0066 0.0121 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0035 0.0046 0.0759
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.004 0.0057 0.0992
Loa Loa (eye worm) hypothetical protein 0.0171 0.0377 0.1254
Echinococcus granulosus transient receptor potential cation channel 0.0047 0.0073 0.0142
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0155 0.0337 0.0582
Schistosoma mansoni biogenic amine receptor 0.0066 0.0121 0.0241
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0014 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0126 0.2418
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Brugia malayi G protein-coupled receptor 0.0066 0.0121 0.0208
Echinococcus granulosus g protein coupled receptor 0.0066 0.0121 0.0238
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0326 0.0754 0.1301
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0261 0.0525
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0047 0.0073 0.0301
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus granulosus cathepsin l1 0.0044 0.0067 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0029 0.0278
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0088 0.1647
Leishmania major hypothetical protein, conserved 0.0047 0.0073 0.1214
Echinococcus granulosus expressed protein 0.0374 0.0873 0.1757
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0112 0.0109
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Schistosoma mansoni nAChR subunit 0.0326 0.0754 0.1521
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0047 0.0073 0.0142
Echinococcus multilocularis dual specificity protein kinase clk2 0.006 0.0107 0.0104
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0054 0.0052
Echinococcus multilocularis expressed protein 0.0374 0.0873 0.087
Loa Loa (eye worm) hypothetical protein 0.0158 0.0346 0.1151
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0103 0.044
Echinococcus granulosus hyperpolarization activated cyclic 0.0047 0.0073 0.0142
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0022 0.0153
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0155 0.0337 0.0335
Schistosoma mansoni hypothetical protein 0.008 0.0155 0.0311
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0048 0.0082
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0014 0.0025
Echinococcus multilocularis muscleblind protein 0.0297 0.0685 0.0683
Brugia malayi Cathepsin L-like precursor 0.0044 0.0067 0.0115
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0014 0.0024
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0054 0.0395
Brugia malayi Carboxylesterase family protein 0.124 0.2985 0.5149
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0135 0.2617
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.004 0.0057 0.0238
Loa Loa (eye worm) patched family protein 0.0018 0.0004 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0047 0.0073 0.007
Echinococcus granulosus 6 phosphofructokinase 0.0218 0.0491 0.0987
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Mycobacterium ulcerans acyl-CoA synthetase 0.0096 0.0195 0.3848
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0007 0.0008
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0326 0.0754 0.2521
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0309 0.0714 0.144
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0035 0.0046 0.0759
Plasmodium vivax glutathione reductase, putative 0.0047 0.0075 0.0564
Brugia malayi cathepsin L-like precursor 0.0029 0.0031 0.0054
Trypanosoma brucei ingi protein (ORF1) 0.0053 0.009 0.075
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Echinococcus granulosus voltage gated potassium channel 0.0047 0.0073 0.0142
Brugia malayi PAS domain containing protein 0.0049 0.0079 0.0136
Brugia malayi hypothetical protein 0.004 0.0057 0.0098
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0047 0.0073 0.0142
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0179 0.0357
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Brugia malayi Patched family protein 0.0018 0.0004 0.0007
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0047 0.0073 0.0142
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0073 0.0146
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0047 0.0073 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0014 0.0024
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0047 0.0073 0.007
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0009 0.0016
Brugia malayi TAR-binding protein 0.0076 0.0146 0.0252
Echinococcus granulosus voltage gated hydrogen channel 1 0.0047 0.0073 0.0142
Brugia malayi PXA domain containing protein 0.0019 0.0007 0.0011
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0047 0.0073 0.007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0058 0.0111
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0073 0.0146
Onchocerca volvulus Huntingtin homolog 0.0123 0.026 0.1113
Brugia malayi Latrophilin receptor protein 2 0.008 0.0155 0.0268
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0112 0.0478
Brugia malayi Serotonin receptor 0.0066 0.0121 0.0208
Trypanosoma brucei trypanothione reductase 0.0047 0.0075 0.0605
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0103 0.7
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0007 0.0013
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0054 0.3398
Entamoeba histolytica cysteine protease, putative 0.0044 0.0067 0.0946
Loa Loa (eye worm) hypothetical protein 0.0209 0.0471 0.157
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0326 0.0754 0.1301
Schistosoma mansoni transient receptor potential channel 0.0047 0.0073 0.0146
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0029 0.0291
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0047 0.0073 0.0142
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0047 0.0073 0.007
Plasmodium vivax serine/threonine kinase-1, putative 0.006 0.0107 0.0815
Entamoeba histolytica phosphofructokinase, putative 0.0218 0.0491 0.7073
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.008 0.0155 0.0663
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0209 0.0471 0.0949
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0047 0.0073 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0096 0.0195 0.3848
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0155 0.0337 0.1123
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0103 0.044
Echinococcus multilocularis G protein coupled receptor 139 0.0066 0.0121 0.0118
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0188 0.0419 0.8478
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0035 0.0046 0.0647
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0014 0.0024
Onchocerca volvulus 0.0209 0.0471 0.2034
Schistosoma mansoni ap endonuclease 0.0039 0.0054 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0135 0.0289 0.0581
Brugia malayi hypothetical protein 0.0026 0.0022 0.0038
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0103 0.1771
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Onchocerca volvulus 0.0066 0.0121 0.0507
Treponema pallidum ribonuclease H (rnhA) 0.0044 0.0066 0.0977
Entamoeba histolytica hypothetical protein 0.0149 0.0323 0.465
Echinococcus granulosus voltage dependent calcium channel 0.0047 0.0073 0.0142
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0047 0.0073 0.0142
Onchocerca volvulus 0.0326 0.0754 0.327
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0096 0.0195 0.3848
Loa Loa (eye worm) hypothetical protein 0.0038 0.0052 0.0165
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Giardia lamblia NADPH oxidoreductase, putative 0.008 0.0155 1
Loa Loa (eye worm) voltage-gated potassium channel 0.0047 0.0073 0.0237
Schistosoma mansoni neuropeptide receptor 0.0066 0.0121 0.0241
Brugia malayi GnHR receptor homolog 0.0066 0.0121 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0066 0.0121 0.0241
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0014 0.0022
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0007 0.0011
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0029 0.041
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0015 0.0198
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trypanosoma cruzi FHA domain containing protein, putative 0.004 0.0057 0.0882
Onchocerca volvulus 0.0081 0.0158 0.0671
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0054 0.0397
Echinococcus granulosus potassium large conductance calcium activated 0.0047 0.0073 0.0142
Entamoeba histolytica phosphofructokinase, putative 0.0218 0.0491 0.7073
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0182
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0073 0.0142
Onchocerca volvulus 0.0036 0.0048 0.019
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0007 0.0008
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.004 0.0057 0.0238
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0031 0.0126
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0015 0.0026
Echinococcus multilocularis serotonin receptor 0.0066 0.0121 0.0118
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0029 0.0408
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.0538 0.1795
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0014 0.0024
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0173 0.0171
Echinococcus multilocularis potassium large conductance calcium activated 0.0047 0.0073 0.007
Echinococcus multilocularis transient receptor potential cation channel 0.0047 0.0073 0.007
Onchocerca volvulus 0.0044 0.0067 0.0272
Onchocerca volvulus 0.0066 0.0121 0.0507
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0171 0.0377 0.065
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0054 0.0227
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Onchocerca volvulus 0.0044 0.0067 0.0272
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0035 0.0046 0.0759
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0047 0.0073 0.0142
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0066 0.0121 0.0118
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0035 0.0046 0.0759
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0029 0.0408
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0035 0.0046 0.0759
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0014 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0147 0.1133
Trichomonas vaginalis helicase, putative 0.0033 0.0039 0.016
Loa Loa (eye worm) hypothetical protein 0.0072 0.0135 0.0445
Brugia malayi ecdysteroid receptor 0.0022 0.0014 0.0024
Brugia malayi Cathepsin L-like precursor 0.0044 0.0067 0.0115
Loa Loa (eye worm) 6-phosphofructokinase 0.0218 0.0491 0.1639
Schistosoma mansoni neuropeptide f receptor 76f 0.0066 0.0121 0.0241
Schistosoma mansoni hypothetical protein 0.008 0.0155 0.0311
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0075 0.0073
Entamoeba histolytica acyl-CoA synthetase, putative 0.0096 0.0195 0.2792
Loa Loa (eye worm) hypothetical protein 0.0087 0.0172 0.0569
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0031 0.0126
Brugia malayi G-protein coupled receptor 0.0066 0.0121 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Echinococcus granulosus potassium voltage gated channel protein 0.0047 0.0073 0.0142
Loa Loa (eye worm) glutathione reductase 0.0047 0.0075 0.0244
Schistosoma mansoni DNA ligase IV 0.004 0.0057 0.0113
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus para nitrobenzyl esterase 0.0209 0.0471 0.0945
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0079 0.0154
Loa Loa (eye worm) CMGC/CLK protein kinase 0.006 0.0107 0.035
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0007 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0008 0.0026
Brugia malayi Cathepsin L-like precursor 0.0044 0.0067 0.0115
Echinococcus granulosus intermediate filament protein 0.0081 0.0158 0.0314
Onchocerca volvulus Putative nachr subunit 0.0326 0.0754 0.327
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0066 0.0121 0.0241
Echinococcus multilocularis cathepsin L 0.0023 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus granulosus short transient receptor potential channel 6 0.0047 0.0074 0.0144
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0253 0.5056
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0171 0.0377 0.065
Brugia malayi hypothetical protein 0.0066 0.0121 0.0208
Echinococcus multilocularis neuropeptides capa receptor 0.0066 0.0121 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0007 0.0019
Brugia malayi Pre-SET motif family protein 0.0842 0.2014 0.3475
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0029 0.0139
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0066 0.0121 0.0241
Echinococcus multilocularis hyperpolarization activated cyclic 0.0047 0.0073 0.007
Trichomonas vaginalis ribonuclease H1, putative 0.0044 0.0066 0.0277
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0029 0.0139
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0029 0.0408
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0047 0.0073 0.0126
Brugia malayi Carboxylesterase family protein 0.0209 0.0471 0.0812
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.006 0.0107 0.0921
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0308 0.0712 0.2379
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0035 0.0046 0.0759
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Trypanosoma brucei hypothetical protein, conserved 0.0053 0.009 0.075
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0155 0.0337 0.0335
Echinococcus multilocularis hyperpolarization activated cyclic 0.0047 0.0073 0.007
Trypanosoma cruzi ribonuclease H1, putative 0.0044 0.0066 0.1072
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0155 0.0337 0.0582
Echinococcus multilocularis ribonuclease H1 0.0044 0.0066 0.0063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0066 0.0121 0.0118
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0014 0.0025
Echinococcus multilocularis cpg binding protein 0.0152 0.033 0.0328
Echinococcus granulosus bloom syndrome protein 0.0043 0.0064 0.0124
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0029 0.0408
Loa Loa (eye worm) hypothetical protein 0.0326 0.0754 0.2521
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0047 0.0073 0.1226
Leishmania major trypanothione reductase 0.0047 0.0075 0.1258
Onchocerca volvulus 0.0066 0.0121 0.0507
Loa Loa (eye worm) voltage-gated potassium channel 0.0047 0.0073 0.0237
Echinococcus multilocularis Niemann Pick C1 protein 0.0301 0.0694 0.0692
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0129 0.0275 0.0913
Brugia malayi CXXC zinc finger family protein 0.0144 0.031 0.0535
Echinococcus granulosus glycine receptor subunit beta 0.0326 0.0754 0.1518
Echinococcus granulosus neuropeptide receptor A26 0.0551 0.1303 0.2627
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0007 0.0011
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0326 0.0754 0.0752
Schistosoma mansoni chromosome transmission fidelity factor 0.004 0.0057 0.0113
Loa Loa (eye worm) hypothetical protein 0.0155 0.0337 0.1123
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Brugia malayi 6-phosphofructokinase 0.0218 0.0491 0.0848
Loa Loa (eye worm) hypothetical protein 0.0253 0.0578 0.1929
Schistosoma mansoni DNA helicase recq1 0.0018 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0218 0.0491 0.2132
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0237
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0014 0.0011
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0073 0.007
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0029 0.0031 0.0346
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0044 0.0067 0.028
Toxoplasma gondii hypothetical protein 0.0047 0.0073 0.1115
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0029 0.0194
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0047 0.0073 0.0142
Leishmania major cathepsin L-like protease 0.0044 0.0067 0.1076
Plasmodium vivax acyl-CoA synthetase, putative 0.0072 0.0135 0.1039
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0223 0.4446
Schistosoma mansoni ap endonuclease 0.0039 0.0054 0.0108
Echinococcus multilocularis dnaJ subfamily B 0.2047 0.4953 0.4952
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0031 0.0436
Echinococcus multilocularis potassium voltage gated channel protein 0.0047 0.0073 0.007
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0035 0.0046 0.0759
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0326 0.0754 0.1301
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0037
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0066 0.0121 0.0118
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0014 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0044 0.0067 0.0282
Echinococcus granulosus calcium activated potassium channel 0.0048 0.0077 0.015
Loa Loa (eye worm) RNA binding protein 0.0076 0.0146 0.0482
Echinococcus granulosus voltage gated potassium channel 0.0047 0.0073 0.0142
Echinococcus granulosus hypothetical protein 0.0066 0.0121 0.0238
Schistosoma mansoni two-pore calcium channel 0.0047 0.0073 0.0146
Brugia malayi Myosin head containing protein 0.0018 0.0004 0.0007
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0155 0.0153
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0014 0.0024
Onchocerca volvulus 0.0305 0.0705 0.3056
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0218 0.0491 1
Schistosoma mansoni lamin 0.0081 0.0158 0.0317
Echinococcus multilocularis 0.0035 0.0046 0.0043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.003 0.0122
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0223 0.4446
Echinococcus granulosus neuropeptide Y receptor 0.0066 0.0121 0.0238
Echinococcus granulosus g protein coupled receptor 0.0066 0.0121 0.0238
Loa Loa (eye worm) hypothetical protein 0.002 0.0009 0.0022
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0182
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0306 0.0706 0.1423
Schistosoma mansoni hypothetical protein 0.0173 0.0382 0.077
Schistosoma mansoni hypothetical protein 0.0433 0.1016 0.2049
Brugia malayi hypothetical protein 0.0019 0.0007 0.0011
Trichomonas vaginalis modulator of drug activity B, putative 0.002 0.0008 0.0026
Giardia lamblia Ribonuclease H 0.0044 0.0066 0.416
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0089 0.0176 0.3372
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0103 0.0786
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0044 0.0067 0.0518
Echinococcus multilocularis GPCR, family 2 0.008 0.0155 0.0153
Echinococcus granulosus rhodopsin orphan GPCR 0.0066 0.0121 0.0238
Plasmodium falciparum cysteine proteinase falcipain 3 0.0044 0.0067 0.4489
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0096 0.0195 0.3848
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0047 0.0073 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0044 0.0067 0.028
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0047 0.0073 0.0146
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0088 0.1546
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0066 0.0121 0.0208
Brugia malayi Cation transporter family protein 0.0326 0.0754 0.1301
Chlamydia trachomatis endonuclease IV 0.0077 0.0147 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0047 0.0073 0.1115
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0047 0.0073 0.0309
Echinococcus multilocularis nibrin 0.004 0.0057 0.0054
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0035 0.0046 0.0759
Schistosoma mansoni neuropeptide receptor 0.0066 0.0121 0.0241
Schistosoma mansoni 6-phosphofructokinase 0.0218 0.0491 0.099
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0066 0.0121 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0188 0.0419 0.0844
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0112 0.0109
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.0242 0.0484
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0075 0.1375
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0014 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0014 0.0024
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0044 0.0067 0.4489
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0068 0.0126 0.2418
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0196 0.0393
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0047 0.0073 0.0126
Loa Loa (eye worm) hypothetical protein 0.004 0.0057 0.0182
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0029 0.0408
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.001 0.0018
Toxoplasma gondii hypothetical protein 0.0047 0.0073 0.1115
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0015 0.0198
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0073 0.0146
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0164 0.0359 0.1195
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0146 0.0482
Brugia malayi hypothetical protein 0.0237 0.0539 0.0929
Echinococcus granulosus Protein patched homolog 1 0.0129 0.0275 0.055
Schistosoma mansoni hypothetical protein 0.0066 0.0121 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0039 0.016
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0047 0.0073 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.0003 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0022 0.0153
Trichomonas vaginalis conserved hypothetical protein 0.008 0.0155 0.0663
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0096 0.0195 0.3848
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0035 0.0046 0.0759
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0044 0.0067 0.028
Loa Loa (eye worm) hypothetical protein 0.0066 0.0121 0.0396
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0035 0.0046 0.0759
Plasmodium falciparum glutathione reductase 0.0047 0.0075 0.5083
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0054 0.0817
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0007 0.0019
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0035 0.0046 0.0759

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 9.2 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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