Detailed information for compound 64807

Basic information

Technical information
  • TDR Targets ID: 64807
  • Name: 1-[2-[3-(5-ethyl-4-phenylimidazol-1-yl)propox y]-6-methylphenyl]-3-pentylurea
  • MW: 448.6 | Formula: C27H36N4O2
  • H donors: 2 H acceptors: 2 LogP: 5.63 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCNC(=O)Nc1c(OCCCn2cnc(c2CC)c2ccccc2)cccc1C
  • InChi: 1S/C27H36N4O2/c1-4-6-10-17-28-27(32)30-25-21(3)13-11-16-24(25)33-19-12-18-31-20-29-26(23(31)5-2)22-14-8-7-9-15-22/h7-9,11,13-16,20H,4-6,10,12,17-19H2,1-3H3,(H2,28,30,32)
  • InChiKey: KQCWGLFEWJJSCA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)propoxy]-6-methyl-phenyl]-3-pentyl-urea
  • 1-[2-[3-(5-ethyl-4-phenyl-1-imidazolyl)propoxy]-6-methylphenyl]-3-pentylurea
  • 1-amyl-3-[2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)propoxy]-6-methyl-phenyl]urea
  • 3-[2-[3-(5-ethyl-4-phenylimidazol-1-yl)propoxy]-6-methylphenyl]-1-pentylurea
  • 3-[2-[3-(5-ethyl-4-phenyl-imidazol-1-yl)propoxy]-6-methyl-phenyl]-1-pentyl-urea
  • 3-[2-[3-(5-ethyl-4-phenyl-1-imidazolyl)propoxy]-6-methylphenyl]-1-pentylurea

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Oryctolagus cuniculus Acyl-CoA:cholesterol acyltransferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis sterol O acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Schistosoma mansoni sterol O-acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133487 All targets in OG5_133487
Schistosoma japonicum ko:K00637 sterol O-acyltransferase [EC2.3.1.26], putative Get druggable targets OG5_133487 All targets in OG5_133487
Echinococcus granulosus sterol O acyltransferase 1 Get druggable targets OG5_133487 All targets in OG5_133487
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133487 All targets in OG5_133487
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Neospora caninum sterol O-acyltransferase, putative Acyl-CoA:cholesterol acyltransferase   305 aa 258 aa 20.2 %
Dictyostelium discoideum diacylglycerol O-acyltransferase 1 Acyl-CoA:cholesterol acyltransferase   305 aa 278 aa 21.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0393 0.2799 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0064
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0707 0.0966
Schistosoma mansoni pap-inositol-14-phosphatase 0.0019 0.0026 0.0025
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0601 0.06
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0179 0.023
Brugia malayi RNA binding protein 0.0061 0.0337 0.0534
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0095 0.0589 0.2053
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0254 0.0629
Echinococcus multilocularis transient receptor potential gamma protein 0.0108 0.0687 0.0687
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0076 0.0065
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.0145
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0019 0.0027 0.0042
Loa Loa (eye worm) RecQ helicase 0.0021 0.0036 0.0057
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Echinococcus multilocularis transient receptor potential cation channel 0.0019 0.0027 0.0027
Loa Loa (eye worm) carboxylesterase 0.0575 0.415 0.6585
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0036 0.0153 0.0144
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0027 0.0019
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0018 0.0005
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0104 0.0657 0.0666
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0104 0.0657 0.0897
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0181 0.1225 0.1224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.009
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0019 0.0027 0.0022
Trypanosoma cruzi inositol polyphosphate 1-phosphatase, putative 0.0019 0.0026 0.0013
Schistosoma mansoni ap endonuclease 0.0018 0.0018 0.0017
Trichomonas vaginalis diphosphonucleoside phosphohydrolase, putative 0.0019 0.0026 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.063 0.0859
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Trichomonas vaginalis apoptosis inducing factor, putative 0.0104 0.0657 0.0897
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0108 0.0108
Brugia malayi G protein-coupled receptor 0.0181 0.1225 0.1943
Schistosoma mansoni hypothetical protein 0.0035 0.0141 0.014
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0657 0.0897
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.059 0.0935
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0069 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.009
Echinococcus granulosus carboxylesterase 5A 0.0575 0.415 0.415
Mycobacterium tuberculosis Carboxylesterase LipT 0.0097 0.0604 0.1371
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0104 0.0657 0.0897
Echinococcus multilocularis serotonin receptor 0.03 0.2109 0.2109
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0026 0.0074 0.0074
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.0259 0.0409
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0209 0.0209
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0018 0.0005
Echinococcus multilocularis serotonin receptor 0.03 0.2109 0.2109
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0035 0.0035
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.0074 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0092 0.011
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0027 0.0032
Trichomonas vaginalis mercuric reductase, putative 0.0393 0.2799 0.3881
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0095 0.0589 0.0591
Trypanosoma cruzi cytochrome P450, putative 0.0078 0.0459 0.0461
Trichomonas vaginalis transmembrane protein nessy, putative 0.0026 0.0074 0.0085
Echinococcus granulosus calcium activated potassium channel 0.0017 0.0007 0.0007
Echinococcus granulosus g protein coupled receptor 0.0181 0.1225 0.1225
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.005 0.0257 0.0862
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Entamoeba histolytica hypothetical protein, conserved 0.0019 0.0027 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0025 0.0069 0.0108
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0804 0.2066
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Onchocerca volvulus 0.0052 0.0272 0.036
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0018 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0035 0.003
Trypanosoma cruzi GUP1, putative 0.0026 0.0074 0.0063
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.063 0.0638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0115 0.0182
Brugia malayi Cathepsin L-like precursor 0.0018 0.0013 0.002
Brugia malayi hypothetical protein 0.0161 0.1078 0.1709
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0104 0.0657 0.1682
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.005 0.0257 0.0561
Plasmodium falciparum glutathione reductase 0.0533 0.3839 1
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0027 0.0032
Onchocerca volvulus 0.0181 0.1225 0.1688
Trypanosoma cruzi cytochrome P450, putative 0.0078 0.0459 0.0461
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0018 0.0011
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0255 0.0404
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.018 0.1222 0.1221
Brugia malayi hypothetical protein 0.0019 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Entamoeba histolytica vacuolar protein sorting 26 0.0026 0.0074 0.0142
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0104 0.0657 0.1479
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0036 0.0153 0.014
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0104 0.0657 0.0897
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0101 0.063 0.1611
Brugia malayi Carboxylesterase family protein 0.0575 0.415 0.6584
Loa Loa (eye worm) hypothetical protein 0.0161 0.1078 0.171
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.1222 0.1222
Giardia lamblia NADH oxidase lateral transfer candidate 0.0393 0.2799 0.652
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0707 0.0966
Trypanosoma cruzi GUP1, putative 0.0026 0.0074 0.0063
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0022
Schistosoma mansoni amine GPCR 0.0181 0.1225 0.1224
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0797 0.0797
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.005 0.0257 0.0862
Schistosoma mansoni sterol O-acyltransferase 1 0.0264 0.1842 0.1841
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0069 0.0068
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0104 0.0657 0.2298
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0027 0.0022
Echinococcus multilocularis musashi 0.0052 0.0272 0.0272
Schistosoma mansoni intermediate filament proteins 0.0052 0.0272 0.0271
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.1225 0.1224
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0019 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0264 0.1842 0.2922
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0104 0.0657 0.1495
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0069 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.1757 0.243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0018 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0026 0.0074 0.0159
Schistosoma mansoni transient receptor potential channel 0.0076 0.0446 0.0445
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0104 0.0657 0.0657
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0027 0.0034
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.005 0.0257 0.0862
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus granulosus methionine synthase reductase 0.0059 0.0319 0.0319
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0074 0.0085
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.0074 0.0074
Brugia malayi FAD binding domain containing protein 0.0059 0.0319 0.0505
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0181 0.1225 0.1225
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.018 0.1222 0.2816
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0035 0.0034
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0181 0.1225 0.1225
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0707 0.0966
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Brugia malayi hypothetical protein 0.0467 0.335 0.5314
Leishmania major hypothetical protein, conserved 0.0104 0.0657 0.0666
Loa Loa (eye worm) hypothetical protein 0.0034 0.0137 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.1757 0.243
Schistosoma mansoni lamin 0.0052 0.0272 0.0271
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0069 0.0158
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0101 0.063 0.0638
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0393 0.2799 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0387 0.0614
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0707 0.1121
Echinococcus multilocularis lamin 0.0052 0.0272 0.0272
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0181 0.1225 0.1944
Echinococcus granulosus hypothetical protein 0.0019 0.0027 0.0027
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0019 0.0027 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.1225 0.1224
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0039 0.0171 0.0272
Echinococcus granulosus neuropeptide FF receptor 2 0.0181 0.1225 0.1225
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0105 0.024
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0069 0.011
Echinococcus multilocularis acetylcholinesterase 0.0575 0.415 0.415
Echinococcus granulosus neuropeptide Y receptor 0.0181 0.1225 0.1225
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.0074 0.0074
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0019 0.0027 0.0022
Trypanosoma brucei C-8 sterol isomerase, putative 0.036 0.2555 0.2626
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0337 0.0337
Schistosoma mansoni amine GPCR 0.0667 0.4831 0.4831
Loa Loa (eye worm) serotonin transporter b 0.0148 0.098 0.1554
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0095 0.0589 0.0589
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0027 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0254 0.0249
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0209 0.0202
Onchocerca volvulus 0.0019 0.0027 0.0019
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.002 0.0035 0.0035
Brugia malayi Bromodomain containing protein 0.003 0.0108 0.017
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0104 0.0657 0.1682
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0027 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.1757 0.243
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.005 0.0257 0.0561
Brugia malayi GnHR receptor homolog 0.0181 0.1225 0.1943
Brugia malayi Retinol dehydrogenase 12 0.0019 0.0027 0.0042
Echinococcus multilocularis sterol O acyltransferase 1 0.0264 0.1842 0.1842
Schistosoma mansoni opsin-like receptor 0.0181 0.1225 0.1224
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Trichomonas vaginalis spcc417.12 protein, putative 0.0097 0.0604 0.0823
Toxoplasma gondii exonuclease III APE 0.0018 0.0018 0.0011
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0248 0.1723 0.1723
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.011
Giardia lamblia Hypothetical protein 0.0084 0.0509 0.1151
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0108 0.0687 0.1089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Brugia malayi Carboxylesterase family protein 0.0097 0.0604 0.0957
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0148 0.098 0.0979
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.1757 0.243
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1116 0.8166 0.8434
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0027 0.0022
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0393 0.2799 0.2799
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0035 0.0034
Loa Loa (eye worm) FAD binding domain-containing protein 0.0095 0.0589 0.0934
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0707 0.1623
Loa Loa (eye worm) TYRA-2 protein 0.0181 0.1225 0.1944
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0019 0.0026 0.0026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0101 0.063 0.063
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0069 0.0069
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0201 0.0262
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0101 0.063 0.0638
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0393 0.2799 0.2882
Onchocerca volvulus 0.0019 0.0027 0.0019
Onchocerca volvulus 0.0181 0.1225 0.1688
Echinococcus granulosus bloom syndrome protein 0.0021 0.0036 0.0036
Echinococcus granulosus acetylcholinesterase 0.0575 0.415 0.415
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.005 0.0257 0.0561
Leishmania major C-8 sterol isomerase-like protein 0.036 0.2555 0.2629
Loa Loa (eye worm) hypothetical protein 0.004 0.0179 0.0284
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Schistosoma mansoni hypothetical protein 0.0181 0.1225 0.1224
Schistosoma mansoni alpha-1 adrenergic receptor 0.0181 0.1225 0.1224
Leishmania major hypothetical protein, conserved 0.0026 0.0074 0.0063
Brugia malayi Dehydrogenases, short chain protein 30 0.0019 0.0027 0.0042
Toxoplasma gondii thioredoxin reductase 0.0533 0.3839 1
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.0014
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0019 0.0027 0.0004
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0657 0.0897
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0035 0.0035
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0027 0.0014
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0104 0.0657 0.2298
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0707 0.1611
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0019 0.0027 0.0027
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0027 0.0027
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0019 0.0027 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0069 0.0069
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.005 0.0257 0.0561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0209 0.0273
Onchocerca volvulus 0.0052 0.0272 0.036
Brugia malayi Pre-SET motif family protein 0.0865 0.6303 1
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0124 0.0804 0.0804
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0069 0.0068
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0027 0.0027
Echinococcus granulosus hypothetical protein 0.0019 0.0027 0.0027
Trypanosoma cruzi NADH dehydrogenase, putative 0.0104 0.0657 0.0666
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0105 0.0128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0259 0.0258
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Brugia malayi MH2 domain containing protein 0.0118 0.0757 0.1199
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0105 0.024
Schistosoma mansoni sulfide quinone reductase 0.0104 0.0657 0.0656
Loa Loa (eye worm) hypothetical protein 0.0044 0.0212 0.0337
Loa Loa (eye worm) flavodoxin family protein 0.0036 0.0153 0.0243
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0019 0.0027 0.0032
Schistosoma mansoni voltage-gated potassium channel 0.0019 0.0024 0.0024
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0707 0.1121
Loa Loa (eye worm) cytochrome P450 family protein 0.0089 0.0547 0.0868
Plasmodium falciparum JmjC domain-containing protein, putative 0.0026 0.0074 0.0159
Treponema pallidum fructose-bisphosphate aldolase 0.0593 0.4283 1
Mycobacterium tuberculosis Monophosphatase CysQ 0.0019 0.0026 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.0014
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0393 0.2799 0.7281
Brugia malayi Protein kinase domain containing protein 0.0029 0.0097 0.0153
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0104 0.0657 0.0657
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0797 0.0796
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0254 0.0629
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.063 0.0629
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Loa Loa (eye worm) hypothetical protein 0.005 0.0255 0.0405
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0104 0.0657 0.1042
Onchocerca volvulus 0.0161 0.1078 0.1483
Schistosoma mansoni neuropeptide f receptor 76f 0.0181 0.1225 0.1224
Brugia malayi 6-phosphofructokinase 0.0111 0.0707 0.1121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0036
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0019 0.0027 0.0022
Brugia malayi oxidoreductase 0.0019 0.0027 0.0042
Plasmodium falciparum transporter, putative 0.0025 0.0069 0.0145
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0027 0.0014
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0148 0.098 0.1554
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0095 0.0589 0.0589
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0026 0.0074 0.0159
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0033 0.0129 0.0129
Schistosoma mansoni transient receptor potential channel 0.0076 0.0448 0.0447
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0035 0.0035
Brugia malayi Carboxylesterase family protein 0.0097 0.0604 0.0957
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0129 0.0115
Trypanosoma cruzi cytochrome p450-like protein, putative 0.005 0.0257 0.0252
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0105 0.0128
Onchocerca volvulus 0.0181 0.1225 0.1688
Echinococcus granulosus phd:f box containing protein 0.0026 0.0074 0.0074
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Plasmodium vivax JmjC domain containing protein 0.0026 0.0074 0.0159
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0196 0.0196
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0979 0.7153 0.7386
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0035 0.0035
Toxoplasma gondii hypothetical protein 0.0019 0.0026 0.0032
Loa Loa (eye worm) hypothetical protein 0.0028 0.009 0.0143
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus histone lysine methyltransferase setb 0.0124 0.0804 0.0804
Loa Loa (eye worm) hypothetical protein 0.0051 0.0265 0.042
Mycobacterium ulcerans monoxygenase 0.0104 0.0657 0.2298
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0069 0.0078
Loa Loa (eye worm) hypothetical protein 0.0104 0.0657 0.1042
Echinococcus granulosus thioredoxin glutathione reductase 0.0533 0.3839 0.3839
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis para nitrobenzyl esterase 0.0097 0.0604 0.0604
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Leishmania major hypothetical protein, conserved 0.0036 0.0153 0.0144
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.1225 0.1225
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0141 0.0141
Leishmania major hypothetical protein, conserved 0.0019 0.0027 0.0014
Echinococcus granulosus death domain containing protein 0.0028 0.009 0.009
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.005 0.0257 0.0561
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.0014
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0272 0.043
Echinococcus granulosus alpha 1A adrenergic receptor 0.0181 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0019 0.0027 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.1222 0.4329
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0575 0.415 0.415
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0097 0.0604 0.1371
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0076 0.0065
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0337 0.0337
Brugia malayi Thioredoxin reductase 0.0533 0.3839 0.609
Echinococcus granulosus transient receptor potential cation channel 0.0016 0.0002 0.0002
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0181 0.1225 0.1225
Trypanosoma cruzi hypothetical protein, conserved 0.0104 0.0657 0.0666
Plasmodium vivax amine transporter, putative 0.0025 0.0069 0.0145
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0078 0.0459 0.1587
Echinococcus granulosus netrin receptor unc 5 0.0028 0.009 0.009
Schistosoma mansoni ankyrin 23/unc44 0.0028 0.009 0.009
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0181 0.1225 0.1944
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0171 0.0171
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0804 0.0803
Echinococcus granulosus allatostatin A receptor 0.0181 0.1225 0.1225
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0025 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.1757 0.2788
Brugia malayi jmjC domain containing protein 0.0097 0.0601 0.0952
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.005 0.0257 0.0862
Schistosoma mansoni hypothetical protein 0.0501 0.3604 0.3604
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Brugia malayi dehydrogenases, short chain protein 2 0.0019 0.0027 0.0042
Trypanosoma brucei glycerol uptake protein, putative 0.0026 0.0074 0.0058
Trypanosoma brucei inositol-1(or 4)-monophosphatase, putative 0.0019 0.0026 0.0008
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0027 0.0022
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0118
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0013 0.0021
Brugia malayi Cathepsin L-like precursor 0.0018 0.0013 0.002
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0027 0.0014
Brugia malayi olfactory channel protein osm-9 0.0016 0.0002 0.0002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0305 0.2151 0.498
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0036 0.0153 0.0194
Mycobacterium tuberculosis Probable monophosphatase 0.0019 0.0026 0.0018
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0035 0.0035
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0104 0.0657 0.0657
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0036 0.0153 0.0194
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0259 0.0258
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0104 0.0657 0.1479
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0707 0.0713
Brugia malayi MBOAT family protein 0.0026 0.0074 0.0117
Loa Loa (eye worm) hypothetical protein 0.0467 0.335 0.5314
Loa Loa (eye worm) carboxylesterase 0.0097 0.0604 0.0958
Echinococcus granulosus neuropeptide Y receptor 0.0181 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.0074 0.0074
Mycobacterium tuberculosis Probable oxidoreductase 0.0594 0.4293 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0104 0.0657 0.1495
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0064
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0209 0.0458
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0979 0.7153 0.7386
Schistosoma mansoni hypothetical protein 0.005 0.0257 0.0257
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0027 0.0022
Brugia malayi Carboxylesterase family protein 0.0097 0.0604 0.0957
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0095 0.0589 0.0591
Trypanosoma brucei inositol polyphosphate 1-phosphatase, putative 0.0019 0.0026 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0593 0.4283 1
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Entamoeba histolytica disulphide oxidoreductase, putative 0.0104 0.0657 0.1507
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0259 0.0259
Trypanosoma cruzi trypanothione reductase, putative 0.0393 0.2799 0.2882
Schistosoma mansoni jumonji/arid domain-containing protein 0.0097 0.0601 0.06
Brugia malayi G-protein coupled receptor 0.0181 0.1225 0.1943
Echinococcus granulosus inositol monophosphatase 1 0.0184 0.1245 0.1245
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.0074 0.0142
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0025 0.0069 0.0157
Echinococcus granulosus hypothetical protein 0.0855 0.6233 0.6233
Leishmania major cytochrome p450-like protein 0.0078 0.0459 0.0461
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0019 0.0027 0.0019
Echinococcus multilocularis survival motor neuron protein 1 0.0467 0.335 0.335
Brugia malayi hypothetical protein 0.0019 0.0027 0.0042
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0181 0.1225 0.1225
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Echinococcus granulosus lamin dm0 0.0052 0.0272 0.0272
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0181 0.1225 0.1225
Echinococcus multilocularis neuropeptide receptor 0.0181 0.1225 0.1225
Loa Loa (eye worm) G-protein coupled receptor 0.0181 0.1225 0.1944
Chlamydia trachomatis sulfite reductase 0.0059 0.0319 0.1057
Brugia malayi dehydrogenases, short chain protein 9 0.0019 0.0027 0.0042
Brugia malayi flavodoxin family protein 0.0036 0.0153 0.0241
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0013 0.0013
Onchocerca volvulus 0.0181 0.1225 0.1688
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0095 0.0589 0.1504
Plasmodium vivax steroid dehydrogenase, putative 0.0019 0.0027 0.0036
Echinococcus multilocularis retinol dehydrogenase 13 0.0019 0.0027 0.0027
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.0108
Onchocerca volvulus 0.0097 0.0604 0.0823
Echinococcus granulosus fmrfamide receptor 0.0181 0.1225 0.1225
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0004
Loa Loa (eye worm) hypothetical protein 0.0586 0.423 0.6711
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0142 0.018
Brugia malayi Death domain containing protein 0.0028 0.009 0.0142
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0019 0.0027 0.001
Schistosoma mansoni rab6-interacting 0.0161 0.1078 0.1077
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.0108
Brugia malayi Inositol-1 0.0184 0.1245 0.1975
Echinococcus granulosus 7tm_1 domain containing protein 0.0181 0.1225 0.1225
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0171 0.017
Onchocerca volvulus 0.0019 0.0027 0.0019
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0022 0.0049 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0209 0.0273
Schistosoma mansoni chromobox protein 0.0071 0.0411 0.041
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0027 0.0022
Plasmodium vivax multidomain scavenger receptor, putative 0.0161 0.1078 0.2782
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0411 0.0554
Schistosoma mansoni neuropeptide receptor 0.0181 0.1225 0.1224
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Trypanosoma brucei oxidoreductase-like protein 0.0019 0.0027 0.001
Onchocerca volvulus 0.0181 0.1225 0.1688
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0069 0.0058
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0393 0.2799 0.7281
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0095 0.0589 0.0595
Echinococcus multilocularis fmrfamide receptor 0.0181 0.1225 0.1225
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0069 0.0068
Onchocerca volvulus 0.0195 0.1328 0.1832
Brugia malayi Augmenter of liver regeneration 0.0033 0.0129 0.0203
Echinococcus multilocularis lipoxygenase domain containing protein 0.0161 0.1078 0.1078
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.132 0.968 1
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0026 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Leishmania major oxidoreductase-like protein 0.0019 0.0027 0.0014
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0104 0.0657 0.1682
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0707 0.1623
Schistosoma mansoni neuropeptide F-like receptor 0.0181 0.1225 0.1224
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Loa Loa (eye worm) MBOAT family protein 0.0026 0.0074 0.0118
Echinococcus multilocularis neuropeptides capa receptor 0.0181 0.1225 0.1225
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0129 0.0119
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Plasmodium vivax SET domain protein, putative 0.0124 0.0804 0.2066
Loa Loa (eye worm) hypothetical protein 0.0124 0.0804 0.1275
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0148 0.098 0.1553
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus voltage gated potassium channel 0.0024 0.0059 0.0059
Schistosoma mansoni diflavin oxidoreductase 0.0047 0.0233 0.0232
Loa Loa (eye worm) melatonin receptor type 1A 0.0181 0.1225 0.1944
Loa Loa (eye worm) dehydrogenase 0.0019 0.0027 0.0043
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0019 0.0027 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0069 0.0069
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0018 0.0028
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0707 0.0717
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.002 0.0035 0.0035
Mycobacterium tuberculosis Probable dehydrogenase 0.0305 0.2151 0.4989
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0069 0.0078
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0019 0.0027 0.0019
Brugia malayi jmjC domain containing protein 0.0026 0.0074 0.0117
Schistosoma mansoni zinc finger protein 0.0026 0.0074 0.0074
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0104 0.0657 0.1041
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.005 0.0257 0.0561
Echinococcus granulosus para nitrobenzyl esterase 0.0097 0.0604 0.0604
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Onchocerca volvulus 0.0104 0.0657 0.0896
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0035 0.0055
Giardia lamblia Hypothetical protein 0.0019 0.0027 0.0022
Brugia malayi Uncoordinated protein 44 0.0028 0.009 0.0142
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0171 0.0171
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0036 0.0153 0.0365
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.0074 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0171 0.022
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0027 0.0027
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.0074 0.0074
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0171
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0025 0.0069 0.0068
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0036 0.0056
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0027 0.0022
Onchocerca volvulus 0.0019 0.0027 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0271 0.0271
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0026 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0041
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0305 0.2151 0.4989
Schistosoma mansoni hypothetical protein 0.0181 0.1225 0.1224
Loa Loa (eye worm) hypothetical protein 0.03 0.2109 0.3346
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0377 0.0852
Brugia malayi neuropeptide F receptor 0.0181 0.1225 0.1943
Loa Loa (eye worm) hypothetical protein 0.0241 0.1673 0.2654
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Schistosoma mansoni neuroligin 3 (S09 family) 0.0097 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Mycobacterium ulcerans dehydrogenase/reductase 0.0019 0.0027 0.0034
Echinococcus granulosus g protein coupled receptor 0.0181 0.1225 0.1225
Brugia malayi Cytochrome P450 family protein 0.005 0.0257 0.0407
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0027 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.1225 0.1225
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0657 0.0897
Echinococcus multilocularis sodium channel protein 0.0119 0.0764 0.0764
Brugia malayi chromobox protein homolog 3 0.004 0.0179 0.0283
Schistosoma mansoni microtubule-associated protein tau 0.1363 1 1
Toxoplasma gondii carbonyl reductase 1, putative 0.0019 0.0027 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0035 0.0034
Trichomonas vaginalis glutathione reductase, putative 0.0393 0.2799 0.3881
Brugia malayi flavodoxin family protein 0.0095 0.0589 0.0933
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0019 0.0026 0.0029
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0105 0.0205
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0019 0.0027 0.0014
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0707 0.0706
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0979 0.7153 0.7385
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0024 0.0059 0.0093
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0027 0.0027
Echinococcus granulosus GPCR family 2 0.0016 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0026 0.0074 0.0159
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis transient receptor potential ion channel A 0.0092 0.057 0.057
Brugia malayi ERG2 and Sigma1 receptor like protein 0.036 0.2555 0.4053
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0097 0.0604 0.0603
Brugia malayi 6-phosphofructokinase 0.0111 0.0707 0.112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Leishmania major pteridine reductase 1 0.0019 0.0027 0.0014
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0201 0.0262
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0095 0.0589 0.0934
Trichomonas vaginalis steroid dehydrogenase, putative 0.0019 0.0027 0.0019
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0104 0.0657 0.1682
Brugia malayi Heterochromatin protein 1 0.0071 0.0411 0.0651
Echinococcus multilocularis allatostatin A receptor 0.0181 0.1225 0.1225
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0022
Schistosoma mansoni lamin 0.0052 0.0272 0.0271
Brugia malayi jmjC domain containing protein 0.0159 0.1065 0.1689
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0026 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0055
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0036 0.0153 0.0194
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0104 0.0657 0.1507
Mycobacterium leprae putative cytochrome p450 0.005 0.0257 0.0543
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.0145
Echinococcus granulosus mitogen activated protein kinase 3 0.0101 0.063 0.063
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0104 0.0657 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0171 0.022
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0757 0.12
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0377 0.0377
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.0145
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0104 0.0657 0.1041
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0181 0.1225 0.1224
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0104 0.0657 0.1682
Treponema pallidum alginate O-acetylation protein (algI) 0.0026 0.0074 0.0132
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0035 0.0034
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0095 0.0589 0.0595
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0171 0.0163
Loa Loa (eye worm) hypothetical protein 0.005 0.0254 0.0403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Brugia malayi hypothetical protein 0.0161 0.1078 0.1709
Loa Loa (eye worm) ctsf protein 0.0018 0.0013 0.0021
Echinococcus multilocularis cysteine protease 0.0018 0.0013 0.0013
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0105 0.0288
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.005 0.0257 0.0862
Loa Loa (eye worm) MBOAT family protein 0.0026 0.0074 0.0118
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.1225 0.1224
Leishmania major 3-keto-dihydrosphingosine reductase 0.0019 0.0027 0.0014
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.005 0.0257 0.0862
Brugia malayi MBOAT family protein 0.0026 0.0074 0.0117
Echinococcus multilocularis jumonji domain containing 1A 0.0026 0.0074 0.0074
Onchocerca volvulus 0.0019 0.0027 0.0019
Onchocerca volvulus 0.0181 0.1225 0.1688
Onchocerca volvulus 0.0097 0.0604 0.0823
Plasmodium vivax flavodoxin domain containing protein 0.0084 0.0509 0.1294
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0337 0.0535
Loa Loa (eye worm) hypothetical protein 0.03 0.2109 0.3346
Trichomonas vaginalis glutamate synthase, putative 0.0104 0.0657 0.0897
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0097 0.0604 0.0823
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0002 0.0002
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0181 0.1225 0.1225
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0069 0.0078
Trypanosoma cruzi myo-inositol-1 phosphatase, putative 0.0019 0.0026 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0071 0.0112
Trypanosoma cruzi NADH dehydrogenase, putative 0.0104 0.0657 0.0666
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0019 0.0027 0.001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0008
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0254 0.0629
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0104 0.0657 0.1682
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0097 0.0604 0.0603
Plasmodium falciparum amino acid transporter, putative 0.0025 0.0069 0.0145
Mycobacterium ulcerans monophosphatase CysQ 0.0019 0.0026 0.0028
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.0074 0.0063
Loa Loa (eye worm) hypothetical protein 0.0238 0.1651 0.2618
Echinococcus granulosus dro:myosuppressin receptor 0.0181 0.1225 0.1225
Leishmania major hypothetical protein, conserved 0.0104 0.0657 0.0666
Echinococcus granulosus arachidonate 5 lipoxygenase 0.071 0.5155 0.5155
Onchocerca volvulus 0.0181 0.1225 0.1688
Leishmania major cytochrome P450 reductase, putative 0.0084 0.0509 0.0512
Brugia malayi hypothetical protein 0.0097 0.0604 0.0957
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0028 0.0092 0.0091
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0305 0.2151 0.4989
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0027 0.0036
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0024 0.0059 0.0059
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0059 0.0059
Brugia malayi ORL1-like opioid receptor 0.0181 0.1225 0.1943
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0104 0.0657 0.2298
Plasmodium falciparum steroid dehydrogenase, putative 0.0019 0.0027 0.0036
Entamoeba histolytica short chain dehydrogenase family protein 0.0019 0.0027 0.0032
Plasmodium falciparum ferrodoxin reductase-like protein 0.0104 0.0657 0.1682
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0049 0.0247 0.0392
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0272 0.0432
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0019 0.0027 0.0027
Onchocerca volvulus 0.0097 0.0604 0.0823
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0021
Giardia lamblia PHD finger protein 15 0.003 0.0108 0.0211
Echinococcus granulosus neuroligin 0.0097 0.0604 0.0604
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.132 0.968 1
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0019 0.0027 0.0022
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0027 0.0014
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0181 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0184 0.1245 0.127
Onchocerca volvulus 0.0019 0.0027 0.0019
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0337 0.0337
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Schistosoma mansoni single-minded 0.0097 0.06 0.06
Schistosoma mansoni netrin receptor unc5 0.0028 0.009 0.009
Brugia malayi Cathepsin L-like precursor 0.0018 0.0013 0.002
Giardia lamblia Nitric oxide synthase, inducible 0.0084 0.0509 0.1151
Loa Loa (eye worm) cytochrome P450 0.005 0.0257 0.0408
Brugia malayi bHLH-PAS transcription factor 0.0072 0.0414 0.0656
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0069 0.0069
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0101 0.063 0.0638
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0022
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.005 0.0257 0.0561
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0091 0.0144
Echinococcus granulosus sterol O acyltransferase 1 0.0264 0.1842 0.1842
Echinococcus multilocularis orexin receptor type 2 0.0181 0.1225 0.1225
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0299
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0026 0.0074 0.0059
Echinococcus multilocularis inositol monophosphatase 0.0019 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0118
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Schistosoma mansoni hypothetical protein 0.0181 0.1225 0.1224
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0377 0.0372
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0181 0.1225 0.1225
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0289 0.2025 0.3212
Schistosoma mansoni glutamate synthase 0.0104 0.0657 0.0656
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0797 0.1822
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.005 0.0257 0.0862
Echinococcus multilocularis g protein coupled receptor 0.0181 0.1225 0.1225
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0104 0.0657 0.0666
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0105 0.0128
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0209 0.0202
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0804 0.0803
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0104 0.0657 0.0657
Echinococcus multilocularis G-protein coupled receptor, putative 0.0181 0.1225 0.1225
Onchocerca volvulus 0.0148 0.098 0.1346
Schistosoma mansoni growth hormone secretagogue receptor 0.0181 0.1225 0.1224
Echinococcus multilocularis serotonin transporter 0.0148 0.098 0.098
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.1113 0.1531
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0105 0.024
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0027 0.001
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0129 0.0302
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0019 0.0027 0.0014
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Echinococcus multilocularis oxidoreductase 0.0019 0.0027 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0027 0.0014
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0593 0.4283 1
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0027 0.0027
Schistosoma mansoni jumonji domain containing protein 0.0139 0.0914 0.0913
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Echinococcus granulosus jun protein 0.0248 0.1723 0.1723
Brugia malayi hypothetical protein 0.005 0.0254 0.0402
Schistosoma mansoni glutamate synthase 0.0104 0.0657 0.0656
Trichomonas vaginalis set domain proteins, putative 0.0984 0.719 1
Mycobacterium ulcerans short-chain type oxidoreductase 0.0019 0.0027 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.005 0.0257 0.0561
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0027 0.0027
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.1116 0.8166 0.8434
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Leishmania major inositol polyphosphate 1-phosphatase, putative 0.0019 0.0026 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Mycobacterium leprae Probable oxidoreductase 0.0019 0.0027 0.0004
Echinococcus multilocularis lysine specific demethylase 6a 0.0026 0.0074 0.0074
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0069 0.0078
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0171 0.036
Toxoplasma gondii hypothetical protein 0.0025 0.0069 0.0145
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0377 0.0598
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.005 0.0257 0.0561
Echinococcus granulosus jumonji domain containing 1A 0.0026 0.0074 0.0074
Schistosoma mansoni sodium/chloride dependent transporter 0.0026 0.0076 0.0075
Giardia lamblia Hypothetical protein 0.0019 0.0026 0.0018
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0069 0.0069
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0049 0.0247 0.0247
Plasmodium falciparum phd finger protein, putative 0.003 0.0108 0.0246
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0018 0.0005
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0026 0.0074 0.0074
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0119 0.0764 0.0776
Echinococcus multilocularis transfer RNA-Lys 0.0072 0.0414 0.0414
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0026 0.0074 0.0074
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0105 0.0215
Brugia malayi MBOAT family protein 0.0026 0.0074 0.0117
Schistosoma mansoni gliotactin 0.0097 0.0604 0.0603
Treponema pallidum NADH oxidase 0.0393 0.2799 0.652
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.099 0.7235 0.7235
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0201 0.0262
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0026 0.0074 0.0074
Loa Loa (eye worm) solute carrier family 6 member 4 0.0148 0.098 0.1554
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0393 0.2799 0.7281
Leishmania major glycerol uptake protein, putative 0.0026 0.0074 0.0063
Schistosoma mansoni histamine h1 receptor 0.0181 0.1225 0.1224
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0018 0.001
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Onchocerca volvulus 0.0181 0.1225 0.1688
Leishmania major hypothetical protein, conserved 0.0026 0.0074 0.0063
Echinococcus granulosus neuropeptide receptor 0.0181 0.1225 0.1225
Schistosoma mansoni inositol monophosphatase 0.0184 0.1245 0.1245
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0019 0.0027 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0179 0.023
Echinococcus granulosus lysine specific demethylase 5A 0.0097 0.0601 0.0601
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0254 0.0249
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Schistosoma mansoni opsin-like receptor 0.0181 0.1225 0.1224
Echinococcus granulosus transient receptor potential ion channel A 0.0092 0.057 0.057
Loa Loa (eye worm) jmjC domain-containing protein 0.0097 0.0601 0.0953
Schistosoma mansoni carbonyl reductase 0.0019 0.0027 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.063 0.0859
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0657 0.0897
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0143 0.0134
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0104 0.0657 0.1495
Schistosoma mansoni adenoreceptor 0.0181 0.1225 0.1224
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0049 0.0049
Leishmania major hypothetical protein, conserved 0.0019 0.0027 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0797 0.2801
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0337 0.0337
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0027 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0141 0.014
Schistosoma mansoni loxhd1 0.0161 0.1078 0.1077
Echinococcus multilocularis fmrfamide receptor 0.0181 0.1225 0.1225
Echinococcus multilocularis neuropeptides capa receptor 0.0181 0.1225 0.1225
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0027 0.0032
Schistosoma mansoni sulfide quinone reductase 0.0104 0.0657 0.0656
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0018 0.0018
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.005 0.0257 0.0862
Schistosoma mansoni hypothetical protein 0.0028 0.009 0.009
Loa Loa (eye worm) fibroinase 0.0018 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.006 0.0329 0.0522
Leishmania major glycerol uptake protein, putative 0.0026 0.0074 0.0063
Loa Loa (eye worm) hypothetical protein 0.0052 0.0272 0.0432
Echinococcus granulosus nuclear factor of activated T cells 5 0.0143 0.0945 0.0945
Echinococcus multilocularis cysteine protease 0.0018 0.0013 0.0013
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0104 0.0657 0.1682
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0105 0.0128
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.005 0.0257 0.0561
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0181 0.1225 0.1224
Schistosoma mansoni 60S ribosomal protein L21 0.0019 0.0024 0.0024
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0184 0.1245 0.1716
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0108 0.0171
Loa Loa (eye worm) hhat protein 0.0026 0.0074 0.0118
Echinococcus multilocularis neuropeptide receptor 0.0181 0.1225 0.1225
Echinococcus multilocularis dro:myosuppressin receptor 0.0181 0.1225 0.1225
Brugia malayi Dopamine receptor 0.0181 0.1225 0.1943
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0209 0.0202
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0184 0.1245 0.4414
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Echinococcus granulosus serotonin transporter 0.0148 0.098 0.098
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0092 0.011
Echinococcus granulosus geminin 0.0501 0.3604 0.3604
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0104 0.0657 0.2298
Brugia malayi Pre-SET motif family protein 0.0124 0.0804 0.1274
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.132 0.968 1
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0019 0.0027 0.0014
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0027 0.001
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0069 0.0058
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0097 0.0604 0.0604
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0393 0.2799 0.6506
Trichomonas vaginalis inositol monophosphatase, putative 0.0019 0.0026 0.0017
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0104 0.0657 0.0657
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Echinococcus granulosus 7TM GPCR rhodopsin 0.0181 0.1225 0.1225
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0104 0.0657 0.0657
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.005 0.0257 0.0862
Echinococcus granulosus lipoxygenase domain containing protein 0.0161 0.1078 0.1078
Brugia malayi phosphofructokinase 0.0111 0.0707 0.112
Echinococcus multilocularis jun protein 0.0248 0.1723 0.1723
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0027 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus granulosus sodium and chloride dependent glycine 0.0025 0.0069 0.0069
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0104 0.0657 0.1495
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1179 0.1624
Schistosoma mansoni jumonji domain containing protein 0.0026 0.0074 0.0074
Echinococcus multilocularis neuropeptide s receptor 0.0181 0.1225 0.1225
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0299
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0104 0.0657 0.0657
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0171 0.0163
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0184 0.1245 0.1274
Schistosoma mansoni carbonyl reductase 0.0019 0.0027 0.0027
Giardia lamblia Kinase, CMGC MAPK 0.0101 0.063 0.1435
Echinococcus granulosus neuropeptide receptor A26 0.0181 0.1225 0.1225
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0027 0.0032
Brugia malayi jmjC domain containing protein 0.0026 0.0074 0.0117
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0095 0.0589 0.0589
Treponema pallidum sodium- and chloride- dependent transporter 0.0148 0.098 0.2255
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0036 0.0031
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0119 0.0764 0.0764
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0181 0.1225 0.1224
Brugia malayi diacylglycerol acyltransferase 0.0026 0.0074 0.0117
Schistosoma mansoni inositol monophosphatase 0.0184 0.1245 0.1245
Echinococcus granulosus carbonyl reductase 1 0.0019 0.0027 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0979 0.7153 0.7386
Loa Loa (eye worm) hypothetical protein 0.0575 0.415 0.6585
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0657 0.0897
Loa Loa (eye worm) hypothetical protein 0.0586 0.423 0.6711
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0069 0.0078
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0027 0.0032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0104 0.0657 0.0666
Echinococcus granulosus BC026374 protein S09 family 0.0097 0.0604 0.0604
Onchocerca volvulus 0.0019 0.0027 0.0019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0001 0.0001
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0209 0.0208
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0069 0.0068
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Leishmania major hypothetical protein, conserved 0.0019 0.0027 0.0014
Brugia malayi Cytochrome P450 family protein 0.0078 0.0459 0.0727
Brugia malayi glutathione reductase 0.0533 0.3839 0.609
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0181 0.1225 0.1224
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0019 0.0027 0.0022
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0069 0.0078
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0181 0.1225 0.1225
Toxoplasma gondii NADPH-glutathione reductase 0.0393 0.2799 0.7281
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) RNA binding protein 0.0061 0.0337 0.0535
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Echinococcus multilocularis glutamate synthase 0.0104 0.0657 0.0657
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0104 0.0657 0.1479
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.005 0.0257 0.0561
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0337 0.0337
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Plasmodium vivax glutathione reductase, putative 0.0533 0.3839 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.005 0.0257 0.0561
Leishmania major glycerol uptake protein, putative 0.0026 0.0074 0.0063
Echinococcus granulosus sodium channel protein 0.0119 0.0764 0.0764
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0104 0.0657 0.0657
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0104 0.0657 0.0661
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.029 0.2032 0.7244
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.029 0.2032 0.4703
Mycobacterium ulcerans monophosphatase CysQ 0.0019 0.0026 0.0028
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0013 0.0013
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0097 0.0604 0.0604
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0181 0.1225 0.1225
Echinococcus multilocularis thioredoxin glutathione reductase 0.0533 0.3839 0.3839
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0105 0.024
Treponema pallidum oxidoreductase 0.0104 0.0657 0.1498
Echinococcus multilocularis somatostatin receptor 0.0181 0.1225 0.1225
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0013 0.0013
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0035 0.003
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.005 0.0257 0.0561
Onchocerca volvulus 0.0019 0.0027 0.0019
Onchocerca volvulus 0.0025 0.0069 0.0078
Echinococcus multilocularis inositol monophosphatase 1 0.0184 0.1245 0.1245
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0019 0.0027 0.0022
Schistosoma mansoni neuropeptide receptor 0.0181 0.1225 0.1224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Schistosoma mansoni ap endonuclease 0.0018 0.0018 0.0017
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0393 0.2799 0.7281
Schistosoma mansoni neuropeptide receptor 0.0181 0.1225 0.1224
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0064
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Leishmania major myo-inositol-1 phosphatase, putative 0.0019 0.0026 0.0013
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0104 0.0657 0.1682
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.1225 0.1225
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0412 0.2944 0.467
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0169 0.0169
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Echinococcus multilocularis carboxylesterase 5A 0.0575 0.415 0.415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0063
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0036
Plasmodium falciparum nitric oxide synthase, putative 0.0095 0.0589 0.1504
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0071 0.0071
Trypanosoma cruzi short chain dehydrogenase, putative 0.0019 0.0027 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0087
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0027 0.0014
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.003 0.0108 0.0107
Echinococcus multilocularis sex peptide receptor 0.0181 0.1225 0.1225
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0019 0.0027 0.001
Onchocerca volvulus 0.0025 0.0069 0.0078
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.013 0.0162
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Schistosoma mansoni transient receptor potential channel 0.0108 0.0687 0.0686
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0377 0.0376
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0181 0.1225 0.1224
Schistosoma mansoni hypothetical protein 0.0181 0.1225 0.1224
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0019 0.0026 0.0017
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0393 0.2799 0.2878
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0181 0.1225 0.1225
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.018 0.1222 0.1222
Loa Loa (eye worm) MBOAT family protein 0.0026 0.0074 0.0118
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0027 0.0036
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0104 0.0657 0.1479
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0459 0.0729
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0337 0.0337
Brugia malayi sulfakinin receptor protein 0.0181 0.1225 0.1943
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Onchocerca volvulus 0.0181 0.1225 0.1688
Onchocerca volvulus 0.0181 0.1225 0.1688
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0019 0.0027 0.001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0025 0.0069 0.0068
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Brugia malayi Doublecortin family protein 0.0161 0.1078 0.1709
Loa Loa (eye worm) neuropeptide F receptor 0.0181 0.1225 0.1944
Leishmania major short chain dehydrogenase/reductase, putative 0.0019 0.0027 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.0014
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0377 0.0377
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.005 0.0257 0.0561
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0104 0.0657 0.0897
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis acetylcholinesterase 0.0575 0.415 0.415
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0027 0.0034
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0299
Echinococcus granulosus acetylcholinesterase 0.0575 0.415 0.415
Schistosoma mansoni jun-related protein 0.0201 0.1379 0.1378
Loa Loa (eye worm) G-protein coupled receptor 0.0181 0.1225 0.1944
Trichomonas vaginalis sulfite reductase, putative 0.0095 0.0589 0.0802
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Mycobacterium ulcerans monophosphatase 0.0019 0.0026 0.0028
Schistosoma mansoni disulfide oxidoreductase 0.0104 0.0657 0.0656
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0022
Echinococcus granulosus TRP transient receptor potential channel 0.0048 0.0241 0.0241
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0184 0.1245 0.1716
Echinococcus multilocularis retinol dehydrogenase 11 0.0019 0.0027 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.1757 0.2787
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0171 0.0369
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0028 0.009 0.009
Leishmania major short chain dehydrogenase, putative 0.0019 0.0027 0.0014
Entamoeba histolytica type A flavoprotein, putative 0.0036 0.0153 0.0327
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0707 0.1121
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0707 0.2477
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0104 0.0657 0.2298
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.1116 0.8166 0.8434
Mycobacterium tuberculosis Possible oxidoreductase 0.0019 0.0027 0.0022
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.0074 0.0142
Brugia malayi Carboxylesterase family protein 0.0097 0.0604 0.0957
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0337 0.0535
Onchocerca volvulus 0.0026 0.0074 0.0085
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0393 0.2799 1
Loa Loa (eye worm) programmed cell death 8 0.0104 0.0657 0.1042
Mycobacterium ulcerans putative regulatory protein 0.0072 0.0414 0.1424
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0069 0.0058
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0091 0.0145
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0027 0.0034
Brugia malayi Serotonin receptor 0.0631 0.4564 0.724
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus granulosus G protein coupled receptor 139 0.0181 0.1225 0.1225
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus granulosus chromobox protein 1 0.0071 0.0411 0.0411
Echinococcus multilocularis g protein coupled receptor 0.0181 0.1225 0.1225
Brugia malayi TAR-binding protein 0.0061 0.0337 0.0534
Brugia malayi PAS domain containing protein 0.0097 0.06 0.0952
Echinococcus granulosus cathepsin l1 0.0018 0.0013 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0209 0.0273
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0104 0.0657 0.2298
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0393 0.2799 0.2882
Schistosoma mansoni lipoxygenase 0.042 0.3004 0.3004
Schistosoma mansoni hypothetical protein 0.0051 0.0258 0.0258
Entamoeba histolytica hypothetical protein 0.0035 0.0141 0.0299
Echinococcus granulosus transient receptor potential gamma protein 0.0108 0.0687 0.0687
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis phd:f box containing protein 0.0026 0.0074 0.0074
Onchocerca volvulus 0.0025 0.0069 0.0078
Onchocerca volvulus 0.0019 0.0027 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.005 0.0257 0.0561
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0019 0.0027 0.0027
Onchocerca volvulus 0.0136 0.089 0.1221
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0255 0.0404
Echinococcus granulosus g protein coupled receptor 0.0181 0.1225 0.1225
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.002 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Echinococcus multilocularis neuropeptide receptor A26 0.0181 0.1225 0.1225
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0097 0.0604 0.0603
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0104 0.0657 0.1507
Loa Loa (eye worm) doublecortin family protein 0.0161 0.1078 0.171
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0084 0.0509 0.069
Mycobacterium ulcerans dehydrogenase 0.0104 0.0657 0.2298
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0101 0.063 0.0638
Schistosoma mansoni amine GPCR 0.0181 0.1225 0.1224
Plasmodium falciparum LCCL domain-containing protein 0.0161 0.1078 0.2782
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0797 0.2801
Echinococcus multilocularis netrin receptor unc 5 0.0028 0.009 0.009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Onchocerca volvulus 0.0181 0.1225 0.1688
Mycobacterium ulcerans dehydrogenase 0.0019 0.0027 0.0034
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Onchocerca volvulus Sepiapterin reductase homolog 0.0019 0.0027 0.0019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0707 0.1596
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0209 0.0202
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0181 0.1225 0.1225
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0104 0.0657 0.1498
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0411 0.0554
Leishmania major hypothetical protein, conserved 0.0104 0.0657 0.0666
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0142 0.018
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0118
Echinococcus granulosus survival motor neuron protein 1 0.0467 0.335 0.335
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0013 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.1757 0.243
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0019 0.0027 0.0022
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0074 0.0118
Schistosoma mansoni acetylcholinesterase 0.0097 0.0604 0.0603
Leishmania major trypanothione reductase 0.0533 0.3839 0.3958
Echinococcus granulosus chromobox protein 1 0.0071 0.0411 0.0411
Plasmodium falciparum thioredoxin reductase 0.0533 0.3839 1
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0019 0.0027 0.0019
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0019 0.0027 0.0034
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0164 0.1103 0.2524
Brugia malayi cytochrome P450 0.005 0.0257 0.0407
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0019 0.0027 0.0034
Trypanosoma brucei NADH dehydrogenase 0.0104 0.0657 0.0661
Leishmania major hypothetical protein, conserved 0.0019 0.0027 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0087
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0707 0.0706
Echinococcus multilocularis conserved hypothetical protein 0.0019 0.0027 0.0027
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0026 0.0074 0.0118
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0025
Toxoplasma gondii flavodoxin domain-containing protein 0.0047 0.0233 0.0574
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0181 0.1225 0.1225
Echinococcus multilocularis steroid dehydrogenase 0.0019 0.0027 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.1179 0.1624
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0305 0.2151 0.4989
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Leishmania major cytochrome p450-like protein 0.005 0.0257 0.0252
Echinococcus granulosus neuropeptide s receptor 0.0181 0.1225 0.1225
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0104 0.0657 0.1507
Mycobacterium tuberculosis Probable dehydrogenase 0.0019 0.0027 0.0022
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0707 0.1615
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0108 0.0107
Trypanosoma brucei hypothetical protein, conserved 0.0104 0.0657 0.0661
Echinococcus multilocularis neuropeptide Y receptor 0.0181 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0025 0.0069 0.0069
Schistosoma mansoni cytochrome P450 reductase 0.0095 0.0589 0.0588
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0707 0.0707
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0129 0.0302
Echinococcus multilocularis calcium activated potassium channel 0.0017 0.0007 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0069 0.0069
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0209 0.0209
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0274 0.0269
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0125 0.0293
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0037 0.002
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0105 0.024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0259 0.0259
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0003
Echinococcus granulosus orexin receptor type 2 0.0181 0.1225 0.1225
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0018 0.0027
Brugia malayi hypothetical protein 0.0032 0.0123 0.0193
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.005 0.0257 0.0862
Echinococcus granulosus g-protein coupled receptor 0.0181 0.1225 0.1225
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0104 0.0657 0.0657
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0069 0.0068
Loa Loa (eye worm) hypothetical protein 0.0028 0.0092 0.0146
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0049 0.0049
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0181 0.1225 0.1943
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0255 0.0405
Echinococcus granulosus short transient receptor potential channel 6 0.0076 0.0446 0.0446
Echinococcus granulosus lamin 0.0052 0.0272 0.0272
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0025 0.0069 0.0069
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0048 0.0241 0.0241
Entamoeba histolytica 3(2),5-bisphosphate nucleotidase, putative 0.0019 0.0026 0.0029
Treponema pallidum flavodoxin 0.0036 0.0153 0.0317
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0026 0.0074 0.0159
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0019 0.0027 0.0022
Brugia malayi MAP kinase sur-1 0.0101 0.063 0.0998
Schistosoma mansoni biogenic amine (5HT) receptor 0.03 0.2109 0.2108
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0013 0.0013
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.005 0.0257 0.0862
Schistosoma mansoni amine GPCR 0.0181 0.1225 0.1224
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0028 0.009 0.0143
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.0074 0.0074
Mycobacterium leprae Possible regulatory protein 0.0025 0.0069 0.0102
Plasmodium vivax hypothetical protein, conserved 0.003 0.0108 0.0246
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0104 0.0657 0.2298
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0804 0.0804
Loa Loa (eye worm) FAD binding domain-containing protein 0.0059 0.0319 0.0506
Echinococcus multilocularis lipoxygenase domain containing protein 0.0161 0.1078 0.1078
Schistosoma mansoni rab6-interacting 0.0161 0.1078 0.1077
Brugia malayi Inositol monophosphatase family protein 0.0019 0.0026 0.004
Brugia malayi jmjC domain containing protein 0.0026 0.0074 0.0117
Toxoplasma gondii selenide, water dikinase 0.0104 0.0657 0.1682
Brugia malayi Dopamine receptor protein 1 0.0181 0.1225 0.1943
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0028 0.009 0.009
Echinococcus multilocularis Ankyrin 0.0028 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0171 0.0171
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0019 0.0027 0.0027
Onchocerca volvulus 0.0072 0.0414 0.0558
Echinococcus multilocularis microtubule associated protein 2 0.1363 1 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0181 0.1225 0.1225
Schistosoma mansoni NADPH flavin oxidoreductase 0.0048 0.0238 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0804 0.0803
Echinococcus multilocularis G protein coupled receptor 139 0.0181 0.1225 0.1225
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0036 0.0031
Echinococcus granulosus neuropeptides capa receptor 0.0181 0.1225 0.1225
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0104 0.0657 0.0657
Chlamydia trachomatis thioredoxin reductase 0.0104 0.0657 0.2276
Giardia lamblia GTOR 0.0044 0.0209 0.0448
Brugia malayi Immunoglobulin I-set domain containing protein 0.0028 0.009 0.0142
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0002 0.0002
Loa Loa (eye worm) glutathione reductase 0.0533 0.3839 0.6091
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.029 0.2032 0.4713
Toxoplasma gondii Erv1 / Alr family protein 0.0033 0.0129 0.0302
Onchocerca volvulus 0.0181 0.1225 0.1688
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0104 0.0657 0.0657
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0337 0.0335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0063
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0095 0.0589 0.0595
Brugia malayi MBOAT family protein 0.0026 0.0074 0.0117
Echinococcus multilocularis chromobox protein 1 0.0071 0.0411 0.0411
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0181 0.1225 0.1225
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0337 0.0534
Brugia malayi Cathepsin L-like precursor 0.0018 0.0013 0.002
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0196 0.0196
Loa Loa (eye worm) thioredoxin reductase 0.0533 0.3839 0.6091
Brugia malayi AKH receptor 0.0181 0.1225 0.1943
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0707 0.1623
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0004
Echinococcus granulosus sex peptide receptor 0.0181 0.1225 0.1225
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0171 0.017
Echinococcus multilocularis carbonyl reductase 1 0.0019 0.0027 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Schistosoma mansoni hypothetical protein 0.0019 0.0026 0.0025
Schistosoma mansoni sodium/chloride dependent transporter 0.0148 0.098 0.0979
Onchocerca volvulus 0.0019 0.0027 0.0019
Brugia malayi Cytochrome P450 family protein 0.0078 0.0459 0.0727
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0019 0.0027 0.0043
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0171 0.0171
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0199 0.1362 0.4834
Brugia malayi hypothetical protein 0.0025 0.0069 0.0108
Leishmania major NADH dehydrogenase, putative 0.0104 0.0657 0.0666
Trichomonas vaginalis inositol monophosphatase, putative 0.0019 0.0026 0.0017
Treponema pallidum thioredoxin reductase (trxB) 0.0104 0.0657 0.1498
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.0259 0.0258
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0019 0.0027 0.0019
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.013 0.0162
Schistosoma mansoni neuropeptide receptor 0.0181 0.1225 0.1224
Brugia malayi Inositol monophosphatase family protein 0.0019 0.0026 0.004
Brugia malayi Serotonin receptor 0.0181 0.1225 0.1943
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0104 0.0657 0.2298
Schistosoma mansoni glutamate synthase 0.0104 0.0657 0.0656
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0019 0.0027 0.0036
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0025 0.0069 0.0068
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0026 0.0074 0.0118
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0248 0.1723 0.1723
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0161 0.1077 0.1709
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0143 0.0134
Echinococcus multilocularis chromobox protein 1 0.0071 0.0411 0.0411
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0025 0.0069 0.0069
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0019 0.0027 0.0027
Echinococcus multilocularis Polycystic kidney disease protein 0.0161 0.1078 0.1078
Echinococcus granulosus short transient receptor potential channel 6 0.0076 0.0448 0.0448
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0104 0.0657 0.0666
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0033 0.0129 0.0119
Echinococcus granulosus lysine specific demethylase 6a 0.0026 0.0074 0.0074
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0657 0.0661
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0036 0.0153 0.0194
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0108 0.0246
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0393 0.2799 0.7281
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.005 0.0257 0.0862
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0101 0.063 0.0634
Brugia malayi Melatonin receptor type 1A 0.0181 0.1225 0.1943
Brugia malayi Dehydrogenases, short chain protein 2 0.0019 0.0027 0.0042
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0393 0.2799 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0018 0.0006
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0019 0.0027 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.0014
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0393 0.2799 0.2798
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0797 0.0796
Schistosoma mansoni hypothetical protein 0.0501 0.3604 0.3604
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0027 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0059 0.0059
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0026 0.0074 0.0074
Schistosoma mansoni chromobox protein 0.0071 0.0411 0.041
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0019 0.0027 0.0042
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0137 0.0217
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0272 0.0432
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0024 0.0059 0.0059
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0104 0.0657 0.0666
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0105 0.0128
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0393 0.2799 0.2799
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0018 0.0011
Onchocerca volvulus 0.0161 0.1078 0.1483
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0035 0.0055
Loa Loa (eye worm) carboxylesterase 0.0097 0.0604 0.0958
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0069 0.0069
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0026 0.0074 0.0074
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Loa Loa (eye worm) hypothetical protein 0.0048 0.0241 0.0382
Echinococcus granulosus neuropeptides capa receptor 0.0181 0.1225 0.1225
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0013 0.0013
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0199 0.1362 0.3145
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0019 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Brugia malayi FAD binding domain containing protein 0.0095 0.0589 0.0933
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0105 0.0128
Echinococcus multilocularis g protein coupled receptor 0.0181 0.1225 0.1225
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0019 0.0027 0.0014
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0026 0.0074 0.0159
Brugia malayi Cathepsin L-like precursor 0.0018 0.0013 0.002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0022
Brugia malayi putative neuropeptide receptor 0.0181 0.1225 0.1943
Giardia lamblia Fructose-bisphosphate aldolase 0.0593 0.4283 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0184 0.1245 0.1274
Echinococcus granulosus Ankyrin 0.0028 0.0092 0.0092
Trypanosoma brucei trypanothione reductase 0.0533 0.3839 0.3955
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0076 0.0065
Schistosoma mansoni biogenic amine (5HT) receptor 0.0181 0.1225 0.1224
Echinococcus granulosus steroid dehydrogenase 0.0019 0.0027 0.0027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0181 0.1225 0.1224
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Brugia malayi Carboxylesterase family protein 0.0575 0.415 0.6584
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0027 0.0014
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0199 0.1362 0.1395
Brugia malayi G-protein coupled receptor 0.0181 0.1225 0.1943
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0019 0.0027 0.0019
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0104 0.0657 0.0897
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0019 0.0027 0.0014
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0153 0.0365
Echinococcus multilocularis JmjC domain containing protein 4 0.0026 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0575 0.415 0.6585
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0104 0.0657 0.1507
Trypanosoma cruzi C-8 sterol isomerase, putative 0.036 0.2555 0.2629
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.005 0.0257 0.0862
Schistosoma mansoni amine GPCR 0.0181 0.1225 0.1224
Brugia malayi hypothetical protein 0.0124 0.0805 0.1277
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0143 0.0945 0.0945
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0594 0.4293 1
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0019 0.0027 0.0027
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.005 0.0257 0.0561
Brugia malayi larval opioid receptor 0.0181 0.1225 0.1943
Leishmania major quinonoid dihydropteridine reductase 0.0019 0.0027 0.0014
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0027 0.001
Echinococcus granulosus neuropeptide receptor 0.0181 0.1225 0.1225
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0076 0.0065
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0019 0.0027 0.0004
Loa Loa (eye worm) hypothetical protein 0.0161 0.1078 0.171
Echinococcus granulosus tar DNA binding protein 0.0061 0.0337 0.0337
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.005 0.0257 0.0862
Giardia lamblia Thioredoxin reductase 0.0104 0.0657 0.1498
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0657 0.0666
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.005 0.0257 0.0561
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0171 0.022
Schistosoma mansoni biogenic amine receptor 0.0181 0.1225 0.1224
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0199 0.1362 0.1391
Loa Loa (eye worm) hypothetical protein 0.0324 0.2287 0.3628
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0019 0.0026 0.0026
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0026 0.0074 0.0074
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.1757 0.243
Echinococcus multilocularis lamin dm0 0.0052 0.0272 0.0272
Onchocerca volvulus Neuropeptide F receptor homolog 0.0181 0.1225 0.1688
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0069 0.0078
Schistosoma mansoni myo inositol monophosphatase 0.0019 0.0026 0.0025
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0069 0.0078
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0184 0.1245 0.1274
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0181 0.1225 0.1688
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0171 0.0159
Trypanosoma brucei cytochrome P450, putative 0.0078 0.0459 0.0457
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0026 0.0074 0.0159
Schistosoma mansoni BC026374 protein (S09 family) 0.0097 0.0604 0.0603
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0094
Entamoeba histolytica type A flavoprotein, putative 0.0036 0.0153 0.0327
Brugia malayi jmjC domain containing protein 0.0026 0.0074 0.0117
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus RUN 0.0161 0.1078 0.1078
Schistosoma mansoni sodium/chloride dependent transporter 0.0025 0.0069 0.0068
Leishmania major short chain dehydrogenase-like protein 0.0019 0.0027 0.0014
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0594 0.4293 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0095 0.0113
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0797 0.2801
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0159 0.1065 0.1065
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.0074 0.0063
Schistosoma mansoni phosphatidylserine receptor 0.0026 0.0074 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0377 0.0376
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0013 0.0013
Brugia malayi SET domain containing protein 0.0016 0.0003 0.0004
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0004 0.0003
Leishmania major cytochrome p450-like protein 0.005 0.0257 0.0252
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0179 0.023
Giardia lamblia Reductase, putative 0.0019 0.0027 0.0022
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0105 0.0128
Leishmania major hypothetical protein, conserved 0.0019 0.0027 0.0014
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.077 0.077
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0181 0.1225 0.1224
Echinococcus granulosus serotonin receptor 0.0181 0.1225 0.1225
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.018 0.1222 0.4329
Echinococcus multilocularis geminin 0.0501 0.3604 0.3604
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0393 0.2799 0.444
Loa Loa (eye worm) CYP4Cod1 0.0078 0.0459 0.0729
Schistosoma mansoni sodium-dependent amino acid transporter 0.0025 0.0069 0.0068
Brugia malayi hypothetical protein 0.0195 0.1328 0.2106
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0001 0.0001
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.063 0.0859
Echinococcus multilocularis lysine specific demethylase 5A 0.0097 0.0601 0.0601
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0209 0.0198
Mycobacterium ulcerans ferredoxin reductase 0.0104 0.0657 0.2298
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0027 0.0034
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0033 0.0129 0.0129
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.038 0.0379
Loa Loa (eye worm) hhat protein 0.0026 0.0074 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0101
Schistosoma mansoni myosin xvIII 0.0181 0.1225 0.1224
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0074 0.0085
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0095 0.0589 0.0589
Echinococcus granulosus Polycystic kidney disease protein 0.0161 0.1078 0.1078
Onchocerca volvulus 0.0181 0.1225 0.1688
Brugia malayi Cathepsin L-like precursor 0.0018 0.0013 0.002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.1116 0.8166 0.8433
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0064
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0019 0.0027 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0104 0.0657 0.0666
Brugia malayi hypothetical protein 0.0324 0.229 0.3633
Giardia lamblia Glutamate synthase 0.0104 0.0657 0.1498
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0707 0.0717
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0049 0.0247 0.0247
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0019 0.0026 0.0017
Echinococcus multilocularis neuropeptide FF receptor 2 0.0181 0.1225 0.1225
Entamoeba histolytica hypothetical protein 0.0026 0.0074 0.0142
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.1113 0.1532
Schistosoma mansoni polycystin 1-related 0.0161 0.1078 0.1077
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0136 0.089 0.089
Echinococcus multilocularis peregrin 0.003 0.0108 0.0108
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0254 0.0629
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.038 0.0379
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0105 0.024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0181 0.1225 0.1225
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0025 0.0069 0.0069
Echinococcus granulosus lipoxygenase domain containing protein 0.0161 0.1078 0.1078
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0019 0.0027 0.0034
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0017 0.001
Toxoplasma gondii cytochrome p450 superfamily protein 0.005 0.0257 0.0638
Loa Loa (eye worm) hepatopoietin HPO2 0.0033 0.0129 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0035 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0059 0.0063
Trypanosoma cruzi trypanothione reductase, putative 0.0533 0.3839 0.3958
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0209 0.0198
Onchocerca volvulus 0.0031 0.0115 0.0141
Echinococcus granulosus cytochrome P450 2K1 0.005 0.0257 0.0257
Echinococcus multilocularis BC026374 protein (S09 family) 0.0097 0.0604 0.0604
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0049 0.0247 0.0391
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0104 0.0657 0.0657
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0594 0.4293 1
Mycobacterium ulcerans glutamate synthase subunit beta 0.0104 0.0657 0.2298
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0025 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0181 0.1225 0.1943
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0026 0.0074 0.0142
Schistosoma mansoni steroid dehydrogenase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0148 0.098 0.1554
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0104 0.0657 0.1682
Schistosoma mansoni hypothetical protein 0.0104 0.0657 0.0656
Echinococcus granulosus tachykinin peptides receptor 99D 0.0181 0.1225 0.1225
Schistosoma mansoni lipoxygenase 0.071 0.5155 0.5155
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0199 0.1362 0.1395
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.005 0.0257 0.0561
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0074 0.0085
Schistosoma mansoni phd/f-box containing protein 0.0026 0.0074 0.0074
Trichomonas vaginalis porcupine, putative 0.0026 0.0074 0.0085
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0393 0.2799 1
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0069 0.0145
Brugia malayi Transient-receptor-potential like protein 0.0048 0.0241 0.038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0181 0.1225 0.1224
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0377 0.0376
Onchocerca volvulus 0.0181 0.1225 0.1688
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.018 0.1222 0.125
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0104 0.0657 0.1495
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0035 0.0035
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0102 0.0123
Plasmodium falciparum thioredoxin reductase 0.0393 0.2799 0.7281
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0026 0.0074 0.0074
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0036 0.0153 0.0144
Echinococcus multilocularis neuroligin 0.0097 0.0604 0.0604
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0199 0.1362 0.1395
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0108 0.0108
Leishmania major p450 reductase, putative 0.0095 0.0589 0.0595
Mycobacterium tuberculosis Probable reductase 0.0305 0.2151 0.4989
Trichomonas vaginalis CMGC family protein kinase 0.0101 0.063 0.0859
Brugia malayi putative neuropeptide receptor NPR1 0.0181 0.1225 0.1943
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0657 0.0666
Entamoeba histolytica type A flavoprotein, putative 0.0036 0.0153 0.0327
Echinococcus multilocularis g-protein coupled receptor 0.0181 0.1225 0.1225
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0027 0.0036
Echinococcus granulosus biogenic amine 5HT receptor 0.03 0.2109 0.2109
Loa Loa (eye worm) hypothetical protein 0.0097 0.0604 0.0958
Loa Loa (eye worm) acetylcholinesterase 1 0.0575 0.415 0.6585
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0104 0.0657 0.2298
Trypanosoma cruzi glycerol uptake protein, putative 0.0026 0.0074 0.0063
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0026 0.0074 0.0074
Onchocerca volvulus 0.0097 0.0604 0.0823
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0033 0.0129 0.0302
Echinococcus multilocularis neuropeptide Y receptor 0.0181 0.1225 0.1225
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0254 0.0245
Schistosoma mansoni hypothetical protein 0.0095 0.059 0.0589
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0019 0.0027 0.0022
Loa Loa (eye worm) hypoxia-induced factor 1 0.0299 0.2104 0.3337
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0143 0.0129
Echinococcus granulosus oxidoreductase 0.0019 0.0027 0.0027
Echinococcus granulosus tm gpcr rhodopsin 0.099 0.7235 0.7235
Schistosoma mansoni hypothetical protein 0.0201 0.1379 0.1378
Schistosoma mansoni biogenic amine receptor 0.0181 0.1225 0.1224
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0071 0.0071
Echinococcus multilocularis methionine synthase reductase 0.0059 0.0319 0.0319
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0797 0.081
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0027 0.0034
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0022
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0305 0.2151 0.4989
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0036
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0797 0.0797
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0593 0.4283 0.5949
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.009
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0036 0.0153 0.0365
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0533 0.3839 0.894
Brugia malayi follicle stimulating hormone receptor 0.0412 0.2944 0.4669
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0164 0.1103 0.2538
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Brugia malayi neuropeptide F receptor 0.0181 0.1225 0.1943
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.1225 0.1225
Brugia malayi Cytochrome P450 family protein 0.0089 0.0547 0.0867
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0142 0.018
Trichomonas vaginalis glutamate synthase, putative 0.0104 0.0657 0.0897
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0019 0.0027 0.001
Brugia malayi Dopamine receptor protein 2 0.0181 0.1225 0.1943
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0171 0.027
Entamoeba histolytica hypothetical protein, conserved 0.0026 0.0074 0.0142
Echinococcus multilocularis sodium and chloride dependent glycine 0.0025 0.0069 0.0069
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Leishmania major cathepsin L-like protease 0.0067 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0027 0.0085 0.0134
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0027 0.0027
Mycobacterium ulcerans ketoacyl reductase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0026 0.0074 0.0159
Trypanosoma brucei glycerol uptake protein, putative 0.0026 0.0074 0.0058
Echinococcus granulosus somatostatin receptor 0.0181 0.1225 0.1225
Leishmania major cathepsin L-like protease 0.0067 0.038 0.0379
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0074 0.0118
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0209 0.0332
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0036 0.0153 0.0144
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0171 0.0171
Toxoplasma gondii hypothetical protein 0.0025 0.0069 0.0145
Mycobacterium ulcerans carveol-like dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0041
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0026 0.0074 0.0074
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0347 0.0551
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0142 0.018
Brugia malayi hypothetical protein 0.0035 0.0141 0.0222
Schistosoma mansoni cytochrome P450 0.005 0.0257 0.0257
Plasmodium vivax thioredoxin reductase, putative 0.0533 0.3839 1
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0019 0.0027 0.0042
Onchocerca volvulus 0.0019 0.0027 0.0019
Echinococcus granulosus WW domain containing oxidoreductase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.0043
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.005 0.0257 0.0862
Brugia malayi Cyclic-nucleotide gated cation channel 0.002 0.0035 0.0054
Echinococcus multilocularis short transient receptor potential channel 6 0.0076 0.0446 0.0446
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.002 0.0035 0.0035
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0095 0.0589 0.0591
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0059 0.0319 0.0318
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0105 0.0205
Echinococcus granulosus retinol dehydrogenase 11 0.0019 0.0027 0.0027
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0101 0.063 0.0638
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0209 0.0458
Loa Loa (eye worm) hypothetical protein 0.0026 0.0074 0.0118
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0074 0.0118
Entamoeba histolytica type A flavoprotein, putative 0.0036 0.0153 0.0327
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0097 0.0604 0.1371
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) hypothetical protein 0.036 0.2555 0.4054
Brugia malayi Hhat protein 0.0026 0.0074 0.0117
Leishmania major glycerol uptake protein, putative 0.0026 0.0074 0.0063
Toxoplasma gondii flavodoxin domain-containing protein 0.0047 0.0233 0.0574
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0459 0.0729
Schistosoma mansoni transient receptor potential channel 4 0.0108 0.0687 0.0686
Brugia malayi RE15519p 0.0181 0.1225 0.1943
Onchocerca volvulus 0.0181 0.1225 0.1688
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0393 0.2799 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0104 0.0657 0.1507
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0095 0.0589 0.0595
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0159 0.1065 0.1065
Schistosoma mansoni survival motor neuron protein 0.0095 0.059 0.0589
Schistosoma mansoni hypothetical protein 0.0034 0.0137 0.0137
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0184 0.1245 0.4414
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0181 0.1225 0.1944
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0104 0.0657 0.0661
Schistosoma mansoni aryl hydrocarbon receptor 0.0097 0.06 0.06
Loa Loa (eye worm) inositol-1 0.0184 0.1245 0.1976
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0036 0.0036
Echinococcus multilocularis mitogen activated protein kinase 0.0101 0.063 0.063
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.071 0.5155 0.5155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0069 0.011
Leishmania major cathepsin L-like protease 0.0067 0.038 0.0379
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0171 0.0163
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Echinococcus multilocularis short transient receptor potential channel 6 0.0076 0.0448 0.0448
Leishmania major short chain dehydrogenase, putative 0.0019 0.0027 0.0014
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0095 0.0589 0.0591
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0025 0.0069 0.0108
Onchocerca volvulus 0.0181 0.1225 0.1688
Schistosoma mansoni retinal dehydrogenase 0.0019 0.0027 0.0027
Leishmania major hypothetical protein, conserved 0.0033 0.0129 0.0119
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0181 0.1225 0.1943
Schistosoma mansoni carbonyl reductase 0.0019 0.0027 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.1225 0.1225
Echinococcus multilocularis 0.005 0.0257 0.0257
Echinococcus granulosus peregrin 0.003 0.0108 0.0108
Brugia malayi glutamate synthase 0.0104 0.0657 0.1041
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.005 0.0257 0.0862
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0101 0.063 0.0999
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0181 0.1225 0.1943
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0184 0.1245 0.2885
Echinococcus granulosus biogenic amine 5HT receptor 0.0181 0.1225 0.1225
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0026 0.0074 0.0074
Onchocerca volvulus Netrin receptor homolog 0.0028 0.009 0.0107
Plasmodium falciparum glutathione reductase 0.0393 0.2799 0.7281
Brugia malayi MBOAT family protein 0.0026 0.0074 0.0117
Mycobacterium ulcerans hypothetical protein 0.0104 0.0657 0.2298
Loa Loa (eye worm) cysteine protease 0.0018 0.0013 0.0021
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0027 0.0004
Echinococcus granulosus inositol monophosphatase 0.0019 0.0026 0.0026
Leishmania major glycerol uptake protein, putative 0.0026 0.0074 0.0063
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0757 0.12
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0289 0.2025 0.3212
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0184 0.1249 0.1981
Trypanosoma brucei protein kinase, putative 0.0101 0.063 0.0634
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Echinococcus multilocularis conserved hypothetical protein 0.0675 0.4891 0.4891
Entamoeba histolytica type A flavoprotein, putative 0.0036 0.0153 0.0327
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0707 0.0966
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0108 0.0246
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.005 0.0257 0.0862
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0148 0.098 0.1554
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0181 0.1225 0.1224
Loa Loa (eye worm) dehydrogenase 0.0019 0.0027 0.0043
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0209 0.0331
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0181 0.1225 0.1943
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0104 0.0657 0.2298
Leishmania major dihydrolipoamide dehydrogenase, putative 0.132 0.968 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Onchocerca volvulus 0.0025 0.0069 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.038 0.0379
Echinococcus granulosus glutamate synthase 0.0104 0.0657 0.0657
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.005 0.0257 0.0862
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0027 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.1225 0.1224
Echinococcus multilocularis GPCR, family 2 0.0016 0.0001 0.0001
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0019 0.0027 0.0022
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0104 0.0657 0.1041
Plasmodium vivax ferrodoxin reductase, putative 0.0104 0.0657 0.1682
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0019 0.0027 0.0036
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.0059 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0161 0.0206
Entamoeba histolytica thioredoxin reductase, putative 0.0104 0.0657 0.1507
Brugia malayi bZIP transcription factor family protein 0.0248 0.1723 0.2733
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0019 0.0027 0.0014
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0105 0.0288
Leishmania major hypothetical protein, conserved 0.005 0.0254 0.0249
Leishmania major protein kinase, putative 0.0026 0.0076 0.0065
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0019 0.0027 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.038 0.0375
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0393 0.2799 0.2882
Loa Loa (eye worm) norepinephrine transporter 0.0148 0.098 0.1554
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0027 0.0022
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0411 0.0652
Onchocerca volvulus Alhambra homolog 0.003 0.0108 0.0131
Leishmania major dehydrogenase-like protein 0.0019 0.0027 0.0014
Brugia malayi hypothetical protein 0.0181 0.1225 0.1943
Echinococcus granulosus o acyltransferase membrane bound domain 0.0026 0.0074 0.0074
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0181 0.1225 0.1944
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0013 0.0013
Schistosoma mansoni short chain dehydrogenase 0.0019 0.0027 0.0027
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0019 0.0027 0.0027
Mycobacterium ulcerans short-chain dehydrogenase 0.0019 0.0027 0.0034
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.0259 0.0411
Brugia malayi hypoxia-induced factor 1 0.0299 0.2104 0.3337
Trypanosoma cruzi p450 reductase, putative 0.0095 0.0589 0.0595
Schistosoma mansoni hypothetical protein 0.0161 0.1078 0.1077
Brugia malayi G protein-coupled receptor F59B2.13 0.0181 0.1225 0.1943
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.0259 0.0259
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.038 0.0379
Loa Loa (eye worm) hypothetical protein 0.0181 0.1225 0.1944
Giardia lamblia Short-chain dehydrogenase, putative 0.0019 0.0027 0.0022
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0033 0.0129 0.0119
Echinococcus granulosus peptide allatostatin:somatostatin 0.0181 0.1225 0.1225
Loa Loa (eye worm) neuropeptide F receptor 0.0181 0.1225 0.1944
Echinococcus multilocularis RUN 0.0161 0.1078 0.1078
Onchocerca volvulus 0.0985 0.7192 1
Brugia malayi PHD-finger family protein 0.003 0.0108 0.017
Loa Loa (eye worm) oxidoreductase 0.0019 0.0027 0.0043
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0105 0.024
Leishmania major protein kinase, putative 0.0031 0.0111 0.0101
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0865 0.6303 1
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0019 0.0027 0.0036
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0181 0.1225 0.1225
Trichomonas vaginalis inositol monophosphatase, putative 0.0184 0.1245 0.1716
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0171 0.0171
Mycobacterium ulcerans oxidoreductase 0.0019 0.0027 0.0034
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0013 0.0013
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0026 0.0074 0.0074
Brugia malayi Tachykinin-like peptides receptor 99D 0.0181 0.1225 0.1943
Onchocerca volvulus 0.0097 0.0604 0.0823
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0184 0.1245 0.322
Mycobacterium ulcerans oxidoreductase 0.0019 0.0027 0.0034
Schistosoma mansoni opsin-like receptor 0.0181 0.1225 0.1224
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.0259 0.0259
Loa Loa (eye worm) hypothetical protein 0.0032 0.0123 0.0196
Toxoplasma gondii oxidoreductase, putative 0.0019 0.0027 0.0036
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0027 0.0034
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.018 0.1222 0.1937
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0125 0.0156
Trypanosoma brucei short-chain dehydrogenase, putative 0.0019 0.0027 0.001
Mycobacterium ulcerans NADH dehydrogenase 0.0104 0.0657 0.2298
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0026 0.0074 0.0074
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0797 0.2047
Schistosoma mansoni hypothetical protein 0.0026 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0142 0.018
Loa Loa (eye worm) hypothetical protein 0.0324 0.229 0.3633
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0104 0.0657 0.1495
Echinococcus granulosus JmjC domain containing protein 4 0.0026 0.0074 0.0074
Entamoeba histolytica hypothetical protein 0.0019 0.0027 0.0032
Mycobacterium ulcerans carboxylesterase, LipT 0.0097 0.0604 0.2108
Onchocerca volvulus 0.0095 0.059 0.0803
Echinococcus granulosus mitogen activated protein kinase 0.0101 0.063 0.063
Mycobacterium tuberculosis Probable oxidoreductase 0.0019 0.0027 0.0022
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.005 0.0257 0.0862
Schistosoma mansoni biogenic amine receptor 0.0181 0.1225 0.1224
Onchocerca volvulus 0.0181 0.1225 0.1688
Mycobacterium leprae Conserved hypothetical protein 0.005 0.0257 0.0543
Brugia malayi intermediate filament protein 0.0052 0.0272 0.043
Echinococcus granulosus intermediate filament protein 0.0052 0.0272 0.0272
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0019 0.0027 0.0022
Echinococcus granulosus single minded 2 0.0075 0.0438 0.0438
Schistosoma mansoni neuropeptide F-like receptor 0.0181 0.1225 0.1224
Schistosoma mansoni protein phosphatase 2C 0.0026 0.0074 0.0074
Onchocerca volvulus 0.0019 0.0027 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.005 0.0257 0.0561
Onchocerca volvulus 0.0019 0.0027 0.0019
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0377 0.0597
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0069 0.0078

Activities

Activity type Activity value Assay description Source Reference
Cholesterol reduction (functional) = -49 % Cholestrol lowering activity in rats after a dose of 4 mg/kg once a day for 2 days ChEMBL. 8496931
Cholesterol reduction (functional) = -28 % Cholestrol lowering activity in rats after a dose of 1 mg/kg once a day for 2 days ChEMBL. 8496931
IC50 (binding) = 0.079 uM Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate ChEMBL. 8496931
IC50 (binding) = 0.079 uM Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit aorta homogenate ChEMBL. 8496931
IC50 (binding) = 0.17 uM Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes ChEMBL. 8496931
IC50 (binding) = 0.17 uM Inhibition against acyl coenzyme A:cholesterol acyltransferase derived from rabbit intestine microsomes ChEMBL. 8496931

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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