Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | aldose reductase, putative | 0.0163 | 0.6523 | 0.8474 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0183 | 0.7544 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0163 | 0.6523 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0047 | 0.0856 | 0.1135 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0163 | 0.6523 | 0.6523 |
Trypanosoma brucei | prostaglandin f synthase | 0.0163 | 0.6523 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0047 | 0.0856 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Onchocerca volvulus | 0.0163 | 0.6523 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Loa Loa (eye worm) | oxidoreductase | 0.0163 | 0.6523 | 0.6523 |
Echinococcus granulosus | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0047 | 0.0856 | 0.1135 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0116 | 0.4213 | 0.5922 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.7544 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0234 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus multilocularis | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.7544 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Brugia malayi | NADH-dependent xylose reductase | 0.0047 | 0.0856 | 0.0856 |
Onchocerca volvulus | 0.0163 | 0.6523 | 1 | |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0163 | 0.6523 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0183 | 0.7544 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0183 | 0.7544 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Loa Loa (eye worm) | oxidoreductase | 0.0163 | 0.6523 | 0.6523 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0163 | 0.6523 | 1 |
Onchocerca volvulus | 0.0047 | 0.0856 | 0.1313 | |
Loa Loa (eye worm) | oxidoreductase | 0.0163 | 0.6523 | 0.6523 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0047 | 0.0856 | 0.0856 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus granulosus | aldehyde reductase | 0.0116 | 0.4213 | 0.5584 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0056 | 0.1276 | 0.1691 |
Entamoeba histolytica | aldose reductase, putative | 0.0163 | 0.6523 | 0.8474 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0163 | 0.6523 | 1 |
Onchocerca volvulus | 0.0163 | 0.6523 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.7013 | 0.9296 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0047 | 0.0856 | 0.1135 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0163 | 0.6523 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0047 | 0.0856 | 0.0856 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0163 | 0.6523 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0056 | 0.1276 | 0.1691 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus multilocularis | geminin | 0.0173 | 0.7013 | 0.9296 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0163 | 0.6523 | 1 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0047 | 0.0856 | 0.1135 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.6523 | 0.6523 |
Giardia lamblia | Aldose reductase | 0.0163 | 0.6523 | 0.5 |
Onchocerca volvulus | 0.0163 | 0.6523 | 1 | |
Toxoplasma gondii | aldose reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Schistosoma mansoni | aldo-keto reductase | 0.0163 | 0.6523 | 0.8647 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.7544 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Schistosoma mansoni | aldo-keto reductase | 0.0163 | 0.6523 | 0.8647 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0163 | 0.6523 | 0.6523 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Onchocerca volvulus | 0.0163 | 0.6523 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.7544 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0163 | 0.6523 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0163 | 0.6523 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.7544 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0163 | 0.6523 | 0.6523 |
Leishmania major | prostaglandin f synthase, putative | 0.0163 | 0.6523 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0163 | 0.6523 | 0.6523 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0047 | 0.0856 | 0.1313 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0163 | 0.6523 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0163 | 0.6523 | 0.6523 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Toxoplasma gondii | aldo-keto reductase | 0.0047 | 0.0856 | 0.1313 |
Echinococcus multilocularis | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Plasmodium vivax | aldehyde reductase, putative | 0.0047 | 0.0856 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Loa Loa (eye worm) | oxidoreductase | 0.0163 | 0.6523 | 0.6523 |
Leishmania major | aldo-keto reductase-like protein | 0.0163 | 0.6523 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.7013 | 0.9296 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Brugia malayi | hypothetical protein | 0.0183 | 0.7544 | 0.7544 |
Giardia lamblia | Aldose reductase | 0.0163 | 0.6523 | 0.5 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0047 | 0.0856 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0163 | 0.6523 | 0.8647 |
Schistosoma mansoni | pol-related | 0.0163 | 0.6523 | 0.8647 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0047 | 0.0856 | 0.5 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0056 | 0.1276 | 0.1691 |
Entamoeba histolytica | aldose reductase, putative | 0.0163 | 0.6523 | 0.8474 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0163 | 0.6523 | 0.8647 |
Echinococcus granulosus | geminin | 0.0173 | 0.7013 | 0.9296 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0163 | 0.6523 | 1 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0047 | 0.0856 | 0.1313 |
Echinococcus multilocularis | aldehyde reductase | 0.0116 | 0.4213 | 0.5584 |
Onchocerca volvulus | 0.0163 | 0.6523 | 1 | |
Mycobacterium ulcerans | oxidoreductase | 0.0163 | 0.6523 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0163 | 0.6523 | 0.8647 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.