Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.3331 | 0.3246 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0653 | 0.0754 |
Loa Loa (eye worm) | glucose-6-phosphate dehydrogenase | 0.009 | 0.2742 | 0.2651 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0653 | 0.0754 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 1 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0225 | 0.8828 | 0.8813 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0653 | 0.0535 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0653 | 0.0754 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.3331 | 0.3246 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0.7128 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0653 | 0.0754 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 1 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.3892 | 0.3815 |
Echinococcus multilocularis | glucose 6 phosphate 1 dehydrogenase | 0.009 | 0.2742 | 0.3738 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.009 | 0.2742 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.3331 | 0.3246 |
Echinococcus multilocularis | geminin | 0.0187 | 0.7128 | 1 |
Giardia lamblia | Glucose-6-phosphate 1-dehydrogenase | 0.0099 | 0.3108 | 0.5 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0099 | 0.3108 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0653 | 0.0754 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.3331 | 0.3246 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 0.1847 | 0.2459 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 1 | 1 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.009 | 0.2742 | 1 |
Mycobacterium tuberculosis | Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) | 0.0031 | 0.0064 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0225 | 0.8828 | 0.8813 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0187 | 0.7128 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0251 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.3892 | 0.3815 |
Brugia malayi | glucose-6-phosphate dehydrogenase | 0.009 | 0.2742 | 0.2651 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0099 | 0.3108 | 0.5 |
Schistosoma mansoni | glucose-6-phosphate 1-dehydrogenase | 0.009 | 0.2742 | 0.3738 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0071 | 0.1847 | 0.1744 |
Trypanosoma brucei | glucose-6-phosphate 1-dehydrogenase | 0.009 | 0.2742 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0239 | 0.9469 | 0.9462 |
Echinococcus granulosus | glucose 6 phosphate 1 dehydrogenase | 0.009 | 0.2742 | 0.3738 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0173 | 0.6495 | 0.4915 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0099 | 0.3108 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1847 | 0.1744 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0653 | 0.0754 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0164 | 0.6094 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Chlamydia trachomatis | glucose-6-phosphate 1-dehydrogenase | 0.009 | 0.2742 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0173 | 0.6495 | 0.4915 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6094 | 0.4333 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0653 | 0.0754 |
Leishmania major | glucose-6-phosphate 1-dehydrogenase, putative | 0.009 | 0.2742 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0187 | 0.7128 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0653 | 0.0535 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.9469 | 0.9462 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.009 | 0.2742 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.3892 | 0.3815 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.