Detailed information for compound 648953

Basic information

Technical information
  • TDR Targets ID: 648953
  • Name: [4-[2-acetamido-3-oxo-3-(1-phenylethylamino)p rop-1-enyl]-2-methoxyphenyl] acetate
  • MW: 396.436 | Formula: C22H24N2O5
  • H donors: 2 H acceptors: 3 LogP: 2.63 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1OC(=O)C)C=C(C(=O)NC(c1ccccc1)C)NC(=O)C
  • InChi: 1S/C22H24N2O5/c1-14(18-8-6-5-7-9-18)23-22(27)19(24-15(2)25)12-17-10-11-20(29-16(3)26)21(13-17)28-4/h5-14H,1-4H3,(H,23,27)(H,24,25)/b19-12-
  • InChiKey: LICFDJBDRRSZSK-UNOMPAQXSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [4-[(Z)-2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxyphenyl] acetate
  • [4-[2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxy-phenyl] acetate
  • [4-[(Z)-2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxy-phenyl] acetate
  • acetic acid [4-[(Z)-2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxyphenyl] ester
  • acetic acid [4-[2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxyphenyl] ester
  • acetic acid [4-[(Z)-2-acetamido-3-keto-3-(1-phenylethylamino)prop-1-enyl]-2-methoxy-phenyl] ester
  • acetic acid [4-[2-acetamido-3-keto-3-(1-phenylethylamino)prop-1-enyl]-2-methoxy-phenyl] ester
  • [4-[(Z)-2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxy-phenyl] ethanoate
  • [4-[2-acetamido-3-oxo-3-(1-phenylethylamino)prop-1-enyl]-2-methoxy-phenyl] ethanoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cathepsin s 0.0015 0.0012 0.0035
Loa Loa (eye worm) hypothetical protein 0.0151 0.0221 0.022
Trypanosoma cruzi cysteine peptidase, putative 0.0174 0.0256 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Echinococcus granulosus allatostatin A receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0013 0.0008 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0037 0.0036
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0014 0.0012
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi Serotonin receptor 0.0018 0.0016 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Loa Loa (eye worm) GMP reductase 0.0018 0.0016 0.0016
Brugia malayi beta-lactamase 0.0024 0.0026 0.0082
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0028 0.0031 0.0936
Toxoplasma gondii cathepsin CPL 0.0046 0.0059 0.0193
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Brugia malayi MH2 domain containing protein 0.008 0.0112 0.0374
Brugia malayi Cathepsin L-like precursor 0.0046 0.0059 0.0193
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0009 0.0002 0.0084
Giardia lamblia NADH oxidase lateral transfer candidate 0.0009 0.0002 0.0016
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.004 0.005 0.0162
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0031
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.0006 0.0015
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0059 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0016 0.0016
Plasmodium falciparum thioredoxin reductase 0.0009 0.0002 0.0002
Schistosoma mansoni histamine h1 receptor 0.0018 0.0016 0.0049
Brugia malayi Cathepsin L-like precursor 0.003 0.0036 0.0115
Loa Loa (eye worm) nuclear hormone receptor 0.0011 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0036 0.5946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0000099203 0.0003
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0026 0.008
Brugia malayi AKH receptor 0.0018 0.0016 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0002 0.0058
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Brugia malayi hypothetical protein 0.0019 0.0019 0.0056
Loa Loa (eye worm) fibroinase 0.0046 0.0059 0.0059
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0009 0.0002 0.0002
Echinococcus multilocularis RUN 0.0016 0.0014 0.0012
Echinococcus granulosus cathepsin L 0.0023 0.0025 0.0023
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0046 0.0059 0.0193
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0016 0.0014
Plasmodium vivax vivapain-1 0.0023 0.0025 0.0078
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.002 0.0019 0.0521
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Echinococcus granulosus cysteine protease 0.0023 0.0025 0.0023
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Schistosoma mansoni cytochrome b 0.1933 0.2959 1
Wolbachia endosymbiont of Brugia malayi cytochrome b subunit of the bc complex 0.1933 0.2959 1
Echinococcus granulosus cathepsin l1 0.0046 0.0059 0.0057
Trypanosoma cruzi GMP reductase 0.0042 0.0054 0.2098
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0225 0.0335 0.0335
Leishmania major cathepsin L-like protease 0.0046 0.0059 0.0261
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0016 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0026 0.008
Leishmania major guanosine monophosphate reductase 0.0042 0.0054 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.0029
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0024 0.0026 0.0026
Toxoplasma gondii thioredoxin reductase 0.0025 0.0028 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0036 0.1071
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0024 0.0027 0.0793
Echinococcus granulosus beta LACTamase domain containing family member 0.0024 0.0026 0.0024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) latrophilin receptor protein 2 0.0151 0.0221 0.022
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0028 0.0031 0.0029
Brugia malayi Latrophilin receptor protein 2 0.0151 0.0221 0.0739
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0016 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.0151 0.0221 0.0739
Entamoeba histolytica cysteine proteinase 2 0.0023 0.0025 0.4054
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0006 0.0004
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) ctsf protein 0.0046 0.0059 0.0059
Giardia lamblia GTOR 0.0012 0.0007 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Loa Loa (eye worm) isocitrate dehydrogenase 0.0008 0.0002 0.0002
Toxoplasma gondii NADPH-glutathione reductase 0.0009 0.0002 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.002 0.0019 0.0059
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0028 0.0031 0.01
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0009 0.0002 0.0063
Schistosoma mansoni hypothetical protein 0.004 0.005 0.0162
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0151 0.0221 0.0219
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.2913
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0016 0.0016
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0058 0.0078 0.854
Leishmania major cathepsin L-like protease 0.0046 0.0059 0.0261
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0026 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0026 0.1022
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0031 0.1222
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0097 0.0138 0.0136
Trypanosoma brucei trypanothione reductase 0.0025 0.0028 0.1021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0026 0.0024
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0226 0.0337 0.0335
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0026 0.008
Echinococcus multilocularis isocitrate dehydrogenase 0.0008 0.0002 0.0000057507
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0014 0.004
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0018 0.0016 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Brugia malayi RE15519p 0.0018 0.0016 0.0049
Brugia malayi follicle stimulating hormone receptor 0.0018 0.0016 0.0049
Echinococcus multilocularis sex peptide receptor 0.0018 0.0016 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Brugia malayi glutathione reductase 0.0025 0.0028 0.0088
Loa Loa (eye worm) hypothetical protein 0.0194 0.0288 0.0287
Toxoplasma gondii aromatic amino acid hydrolase AAH1 0.1432 0.219 0.74
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Plasmodium vivax thioredoxin reductase, putative 0.0025 0.0028 0.0088
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0025 0.0078
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0008 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0014 0.001 0.0028
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0226 0.0337 0.0335
Leishmania major trypanothione reductase 0.0025 0.0028 0.0118
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0028 0.0031 0.1222
Trypanosoma cruzi target of rapamycin kinase 3 0.0009 0.0003 0.0129
Onchocerca volvulus 0.0018 0.0016 0.0624
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.0025 0.0976
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0064 0.0087 0.3801
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0009 0.0002 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.0024 0.0026 0.0783
Trichomonas vaginalis glucosylceramidase, putative 0.0225 0.0335 1
Trypanosoma cruzi trypanothione reductase, putative 0.0009 0.0002 0.0091
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0225 0.0335 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Loa Loa (eye worm) hypothetical protein 0.0029 0.0033 0.0033
Brugia malayi G protein-coupled receptor 0.0018 0.0016 0.0049
Brugia malayi cathepsin L-like precursor 0.003 0.0036 0.0115
Brugia malayi beta-lactamase family protein 0.0024 0.0026 0.0082
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0016 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0031 0.1222
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0026 0.0024
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0016 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0008 0.0002 0.0058
Onchocerca volvulus 0.0018 0.0016 0.0624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Loa Loa (eye worm) PHD-finger family protein 0.0014 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0008 0.0002 0.0058
Mycobacterium ulcerans hypothetical protein 0.0024 0.0026 0.4637
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0016 0.0049
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0006 0.0015
Plasmodium vivax vivapain-3 0.0023 0.0025 0.0078
Mycobacterium tuberculosis Conserved protein 0.0024 0.0026 0.1079
Plasmodium falciparum glutathione reductase 0.0009 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0102
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Treponema pallidum NADH oxidase 0.0009 0.0002 0.5
Onchocerca volvulus 0.0018 0.0016 0.0624
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0002 0.0058
Echinococcus multilocularis cysteine protease 0.0046 0.0059 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0016 0.0014
Schistosoma mansoni bromodomain containing protein 0.0042 0.0054 0.0176
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Echinococcus granulosus neuropeptide s receptor 0.0396 0.0597 0.0595
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0018 0.0016 0.0624
Schistosoma mansoni hypothetical protein 0.0019 0.0019 0.0056
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0028 0.0031 0.01
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0028 0.0031 0.1222
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0025 0.0028 0.115
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0026 0.0024
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0059 0.0193
Leishmania major cathepsin L-like protease 0.0174 0.0256 0.116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0016 0.0014 0.0012
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0026 0.008
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0008 0.0022
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0024 0.0026 0.0024
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Onchocerca volvulus 0.003 0.0036 0.1463
Schistosoma mansoni amine GPCR 0.0018 0.0016 0.0049
Onchocerca volvulus Glucosylceramidase homolog 0.0148 0.0216 0.9229
Leishmania major cathepsin L-like protease 0.0046 0.0059 0.0261
Brugia malayi nuclear receptor NHR-67 0.0011 0.0006 0.0015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0156 0.0228 0.6813
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0151 0.0221 0.0739
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0009 0.0002 0.0091
Plasmodium vivax glutathione reductase, putative 0.0025 0.0028 0.0088
Brugia malayi Dopamine receptor protein 2 0.0018 0.0016 0.0049
Echinococcus multilocularis beta LACTamase domain containing family member 0.0024 0.0026 0.0024
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0016 0.0014
Trypanosoma cruzi major cysteine proteinase, putative 0.0136 0.0199 0.7767
Schistosoma mansoni opsin-like receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Leishmania major hypothetical protein, conserved 0.0024 0.0026 0.0111
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0009 0.0002 0.0002
Mycobacterium ulcerans esterase/lipase LipP 0.0024 0.0026 0.4637
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0058 0.0078 0.3361
Trypanosoma cruzi cysteine protease, putative 0.0023 0.0025 0.0976
Onchocerca volvulus 0.0016 0.0014 0.0516
Schistosoma mansoni hypothetical protein 0.0151 0.0221 0.0739
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0028 0.0031 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0008 0.0002 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0031 0.01
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0016 0.0014
Brugia malayi GnHR receptor homolog 0.0018 0.0016 0.0049
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.0006 0.0015
Leishmania major cathepsin L-like protease 0.0046 0.0059 0.0261
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0121 0.0176 0.0176
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0016 0.0014 0.0012
Entamoeba histolytica hypothetical protein 0.002 0.0019 0.301
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0016 0.0049
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0008 0.0002 0.0000057507
Onchocerca volvulus Cathepsin L homolog 0.0046 0.0059 0.246
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Onchocerca volvulus 0.0018 0.0016 0.0624
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0015 0.0012 0.0035
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0028 0.0031 0.1222
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0016 0.0014
Trypanosoma brucei GMP reductase 0.0042 0.0054 0.2042
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0012 0.0007 0.0262
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.008 0.0112 0.0112
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0009 0.0002 0.0063
Brugia malayi G-protein coupled receptor 0.0018 0.0016 0.0049
Leishmania major hypothetical protein, conserved 0.0028 0.0031 0.0135
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0045 0.0059 0.0057
Plasmodium vivax cytochrome b 0.1933 0.2959 1
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0016 0.0014
Schistosoma mansoni nuclear receptor 0.0011 0.0006 0.0015
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Trichomonas vaginalis penicillin-binding protein, putative 0.0024 0.0026 0.0783
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Plasmodium vivax vivapain-2 0.0046 0.0059 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0025 0.0748
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0278 0.0417 0.0415
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.002 0.0019 0.0059
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0042 0.0054 0.2098
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0042 0.0054 0.2098
Brugia malayi conserved hypotetical protein 0.0011 0.0006 0.0015
Leishmania major hypothetical protein, conserved 0.001 0.0005 0.0013
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0016 0.0049
Echinococcus granulosus Polycystic kidney disease protein 0.0016 0.0014 0.0012
Brugia malayi sulfakinin receptor protein 0.0018 0.0016 0.0049
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0006 0.0189
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1356 0.2073 0.2071
Onchocerca volvulus 0.0018 0.0016 0.0624
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0042 0.0054 0.0175
Brugia malayi nuclear receptor NHR-88 0.0011 0.0006 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0102
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Plasmodium falciparum thioredoxin reductase 0.0025 0.0028 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0031 0.0031
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0016 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0225 0.0335 1
Onchocerca volvulus Cathepsin F homolog 0.0046 0.0059 0.246
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0019 0.0753
Schistosoma mansoni survival motor neuron protein 0.004 0.005 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0026 0.0958
Loa Loa (eye worm) hypothetical protein 0.6513 1 1
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0011 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis zinc finger protein 0.0013 0.0009 0.0007
Plasmodium falciparum glutathione reductase 0.0025 0.0028 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0026 0.008
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0012 0.0007 0.0005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi putative neuropeptide receptor 0.0018 0.0016 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0058 0.0078 0.3361
Brugia malayi nuclear hormone receptor 0.0011 0.0006 0.0015
Echinococcus multilocularis serotonin receptor 0.0018 0.0016 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0024 0.0026 0.1079
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.116
Trypanosoma cruzi cruzipain precursor, putative 0.0015 0.0012 0.047
Schistosoma mansoni methyl-cpg binding protein mbd 0.0011 0.0007 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0014 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0002 0.0000057507
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0019 0.0579
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0042 0.0054 0.2301
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0028 0.0031 0.1222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0026 0.0026
Onchocerca volvulus 0.0018 0.0016 0.0624
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0016 0.0014
Brugia malayi larval opioid receptor 0.0018 0.0016 0.0049
Echinococcus granulosus methyl CpG binding domain protein 2 0.0011 0.0007 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Onchocerca volvulus 0.0046 0.0059 0.246
Brugia malayi nuclear hormone receptor 0.0024 0.0026 0.008
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0026 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0004 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Brugia malayi hypothetical protein 0.0013 0.0008 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0007 0.0204
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0016 0.0014
Echinococcus multilocularis serotonin receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Plasmodium vivax multidomain scavenger receptor, putative 0.0016 0.0014 0.004
Entamoeba histolytica cysteine protease, putative 0.0046 0.0059 1
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0028 0.0031 0.01
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.0006 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0024 0.0026 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0009 0.0002 0.0002
Leishmania major inosine-5-monophosphate dehydrogenase 0.0042 0.0054 0.0237
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0016 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0046 0.0059 0.1761
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0016 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0026 0.0958
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0226 0.0337 0.1133
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.01
Schistosoma mansoni cathepsin F (C01 family) 0.003 0.0036 0.0115
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0024 0.0026 0.0082
Brugia malayi hypothetical protein 0.0016 0.0014 0.004
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.0006 0.0004
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.002 0.0019 0.301
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0026 0.008
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0042 0.0054 0.0052
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0006 0.0004
Brugia malayi Biopterin-dependent aromatic amino acid hydroxylase family protein 0.1432 0.219 0.74
Loa Loa (eye worm) hypothetical protein 0.0326 0.0489 0.0489
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0016 0.0016
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.01
Schistosoma mansoni amine GPCR 0.0018 0.0016 0.0049
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0064 0.0087 0.3801
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0016 0.0014
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0031 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.0225 0.0335 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0011 0.0006 0.0006
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0046 0.0059 0.0193
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.01
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0024 0.0026 0.1079
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.002 0.0019 0.0017
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0031 0.1222
Onchocerca volvulus 0.002 0.002 0.0774
Onchocerca volvulus 0.0024 0.0026 0.1025
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0016 0.0014
Onchocerca volvulus 0.004 0.005 0.2068
Loa Loa (eye worm) glutathione reductase 0.0025 0.0028 0.0028
Loa Loa (eye worm) doublecortin family protein 0.0016 0.0014 0.0014
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.0006 0.0015
Schistosoma mansoni hypothetical protein 0.0326 0.0489 0.1648
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0199 0.0295 0.099
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0016 0.0014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0151 0.0221 0.0219
Mycobacterium tuberculosis Probable hydrolase 0.0024 0.0026 0.1079
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0016 0.0049
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0028 0.0031 0.0029
Onchocerca volvulus 0.0018 0.0016 0.0624
Schistosoma mansoni hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) phosphatidylinositol 3 0.0012 0.0007 0.0007
Echinococcus multilocularis somatostatin receptor 0.0018 0.0016 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0016 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0026 0.0026
Brugia malayi tailless protein 0.0011 0.0006 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Brugia malayi Doublecortin family protein 0.0016 0.0014 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0008 0.0002 0.0002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0008 0.0002 0.0058
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.0006 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0025 0.4054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0476 0.0721 0.2431
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0031 0.0936
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Schistosoma mansoni lipoxygenase 0.0097 0.0138 0.046
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0121 0.0176 0.7489
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi Cathepsin L-like precursor 0.0046 0.0059 0.0193
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0028 0.0031 0.0029
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.005 0.0048
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.0006 0.0004
Schistosoma mansoni amine GPCR 0.0018 0.0016 0.0049
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0008 0.0002 0.007
Plasmodium falciparum cysteine proteinase falcipain 1 0.0023 0.0025 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0000099203 0.0003
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.0006 0.0004
Schistosoma mansoni lipoxygenase 0.0068 0.0093 0.0308
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0022 0.0023 0.0934
Onchocerca volvulus 0.0018 0.0016 0.0624
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0008 0.0002 0.0058
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0019 0.0688
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0002 0.0000057507
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0019 0.0019 0.0017
Echinococcus granulosus cytochrome B 0.1933 0.2959 0.2958
Echinococcus granulosus g protein coupled receptor 0.0018 0.0016 0.0014
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0009 0.0002 0.0069
Loa Loa (eye worm) hypothetical protein 0.0101 0.0144 0.0144
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0026 0.0024
Echinococcus granulosus sex peptide receptor 0.0018 0.0016 0.0014
Echinococcus granulosus zinc finger protein 0.0013 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0018 0.0016 0.0624
Brugia malayi Papain family cysteine protease containing protein 0.0046 0.0059 0.0193
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0019 0.0019 0.0017
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis neuropeptide s receptor 0.0396 0.0597 0.0595
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0021 0.0021 0.0065
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi nuclear receptor RXR 0.0011 0.0006 0.0015
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.004 0.005 0.925
Brugia malayi Cathepsin L-like precursor 0.0046 0.0059 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0058
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0028 0.0031 0.0029
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Schistosoma mansoni amine GPCR 0.0018 0.0016 0.0049
Brugia malayi hypothetical protein 0.0013 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0014
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi Dopamine receptor protein 1 0.0018 0.0016 0.0049
Schistosoma mansoni polycystin 1-related 0.0016 0.0014 0.004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0012 0.0007 0.0017
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0009 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Schistosoma mansoni transcription factor LCR-F1 0.0019 0.0019 0.0056
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0017 0.0015 0.0452
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0026 0.0026
Toxoplasma gondii target of rapamycin (TOR), putative 0.0009 0.0003 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0026 0.008
Mycobacterium leprae Probable lipase LipE 0.0024 0.0026 0.0958
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0008 0.0002 0.0058
Brugia malayi beta-lactamase family protein 0.0024 0.0026 0.0082
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0026 0.0024
Echinococcus granulosus fetal alzheimer antigen falz 0.0015 0.0012 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0008 0.0002 0.0058
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1681 0.2573 0.8694
Loa Loa (eye worm) tryptophan hydroxylase 1 0.1432 0.219 0.219
Onchocerca volvulus 0.0024 0.0026 0.1048
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.002 0.0019 0.0017
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0014
Brugia malayi latrophilin 2 splice variant baaae 0.0326 0.0489 0.1648
Leishmania major cathepsin L-like protease 0.0046 0.0059 0.0261
Loa Loa (eye worm) beta-lactamase 0.0024 0.0026 0.0026
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0009 0.0002 0.0001
Mycobacterium tuberculosis Probable lipase LipD 0.0024 0.0026 0.1079
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0028 0.0031 0.1222
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0059 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.002 0.002 0.0061
Brugia malayi Melatonin receptor type 1A 0.0018 0.0016 0.0049
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Giardia lamblia Hypothetical protein 0.0028 0.0031 0.0879
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.002 0.0019 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0026 0.008
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0026 0.0024
Mycobacterium tuberculosis Conserved protein 0.0024 0.0026 0.1079
Plasmodium falciparum cysteine proteinase falcipain 3 0.0046 0.0059 0.0193
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0026 0.008
Loa Loa (eye worm) DR-78 0.0011 0.0006 0.0006
Schistosoma mansoni zinc finger protein 0.0011 0.0006 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Echinococcus granulosus cathepsin l cysteine peptidase 0.0046 0.0059 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0007 0.0204
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Brugia malayi neuropeptide F receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0047 0.0062 0.0062
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0002 0.0058
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0009 0.0002 0.0002
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.01
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1373 0.21 0.2098
Echinococcus granulosus neuropeptide receptor 0.0018 0.0016 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0026 0.0024
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0016 0.0014
Schistosoma mansoni adenoreceptor 0.0018 0.0016 0.0049
Brugia malayi steroid hormone receptor 0.0024 0.0026 0.008
Schistosoma mansoni hypothetical protein 0.0151 0.0221 0.0739
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.0025 0.0912
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0046 0.0059 0.0057
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0026 0.0024
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0016 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0019 0.0579
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0016 0.0014
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0028 0.0031 0.01
Brugia malayi Serotonin receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0151 0.0221 0.0739
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0026 0.0783
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0026 0.0024
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0025 0.0078
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0025 0.4054
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0101 0.0144 0.0144
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0009 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0008 0.0002 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0028 0.0031 0.116
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.2913
Toxoplasma gondii phenylalanine-4-hydroxylase 0.1432 0.219 0.74
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0025 0.0748
Loa Loa (eye worm) nuclear receptor NHR-67 0.0011 0.0006 0.0006
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0016 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0042 0.0054 0.0173
Brugia malayi PHD-finger family protein 0.0017 0.0015 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0026 0.0024
Schistosoma mansoni zinc finger protein 0.0013 0.0009 0.0024
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Trypanosoma cruzi cruzipain precursor, putative 0.0174 0.0256 1
Schistosoma mansoni neuropeptide receptor 0.0018 0.0016 0.0049
Leishmania major cAMP-specific phosphodiesterase, putative 0.0028 0.0031 0.0135
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0016 0.0014
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0042 0.0054 0.2098
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0024 0.0027 0.4315
Echinococcus granulosus g protein coupled receptor 0.0018 0.0016 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0091
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0008 0.0002 0.0000057507
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Brugia malayi neuropeptide F receptor 0.0018 0.0016 0.0049
Schistosoma mansoni biogenic amine (5HT) receptor 0.0278 0.0417 0.1403
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.2913
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0031 0.1222
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0026 0.008
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0026 0.008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0028 0.0031 0.01
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0006 0.0004
Onchocerca volvulus 0.0018 0.0016 0.0624
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0026 0.0024
Leishmania major cathepsin L-like protease 0.0174 0.0256 0.116
Trypanosoma cruzi ISWI complex protein 0.001 0.0005 0.018
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0012 0.0007 0.0193
Onchocerca volvulus Huntingtin homolog 0.0101 0.0144 0.6109
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0016 0.0014
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0009 0.0002 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0046 0.0059 0.1761
Brugia malayi cytochrome b 0.1933 0.2959 1
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0028 0.0031 0.116
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0016 0.0014
Loa Loa (eye worm) thioredoxin reductase 0.0025 0.0028 0.0028
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0009 0.0003 0.0059
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0226 0.0337 0.0335
Echinococcus multilocularis GPCR, family 2 0.0151 0.0221 0.0219
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0006 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0091
Echinococcus granulosus cathepsin l1 0.003 0.0036 0.0034
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0026 0.0024
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0016 0.0016
Echinococcus granulosus cathepsin L cysteine proteinase 0.0046 0.0059 0.0057
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0011 0.0006 0.0759
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0027 0.0083
Onchocerca volvulus Putative GMP reductase 0.0018 0.0016 0.0603
Trypanosoma cruzi cysteine proteinase, putative 0.0023 0.0025 0.0976
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0009 0.0002 0.0001
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0009 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0059 0.2304
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0028 0.0031 0.0029
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0009 0.0002 0.0002
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0028 0.0031 0.0936
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0013 0.0008 0.0006
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0012 0.0007 0.0022
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0023 0.0025 0.0976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0008 0.0002 0.0058
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0022 0.0023 0.0479
Echinococcus multilocularis Polycystic kidney disease protein 0.0016 0.0014 0.0012
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0024 0.0027 0.0793
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0058 0.0078 0.3361
Loa Loa (eye worm) hypothetical protein 0.0226 0.0337 0.0337
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0016 0.0049
Schistosoma mansoni neuropeptide receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0018 0.0016 0.0624
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0008 0.0002 0.0058
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0016 0.0016
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.0006 0.0015
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0042 0.0054 0.2042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0031 0.116
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0008 0.0022
Plasmodium vivax phosphodiesterase gamma, putative 0.0028 0.0031 0.01
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0025 0.4054
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) transcription factor SMAD2 0.008 0.0112 0.0112
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0016 0.0014
Trypanosoma cruzi cysteine peptidase, putative 0.0174 0.0256 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0026 0.0026
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0012 0.047
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0018 0.0016 0.0047
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0028 0.0031 0.1222
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0016 0.0014
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.005 0.0048
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0031 0.01
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0016 0.0014
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0016 0.0014
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0019 0.0753
Schistosoma mansoni hypothetical protein 0.0018 0.0016 0.0049
Brugia malayi Bromodomain containing protein 0.005 0.0066 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0102
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0015 0.0012 0.0035
Brugia malayi hypothetical protein 0.0011 0.0006 0.0015
Brugia malayi Cathepsin L-like precursor 0.0046 0.0059 0.0193
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Schistosoma mansoni coup transcription factor 0.0024 0.0026 0.008
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.116
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0012 0.0012
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0017 0.0015 0.0452
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0016 0.0014
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0002 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0026 0.008
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Schistosoma mansoni rab6-interacting 0.0016 0.0014 0.004
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0015 0.0012 0.001
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0028 0.0031 0.116
Brugia malayi Cathepsin L-like precursor 0.003 0.0036 0.0115
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.002 0.002 0.0018
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0058 0.0078 0.3361
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0016 0.0014
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Onchocerca volvulus 0.0011 0.0006 0.0189
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0016 0.0049
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0009 0.0002 0.0069
Brugia malayi ORL1-like opioid receptor 0.0018 0.0016 0.0049
Brugia malayi Thioredoxin reductase 0.0025 0.0028 0.0088
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0045 0.0059 0.0057
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0199 0.0295 0.0293
Trypanosoma cruzi major cysteine proteinase, putative 0.0008 0.0002 0.007
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0091
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0025 0.0078
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0024 0.0026 0.4637
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0026 0.0026
Onchocerca volvulus 0.0018 0.0016 0.0624
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0008 0.0002 0.0058
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) bromodomain containing protein 0.0012 0.0007 0.0007
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0009 0.0003 0.0007
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0042 0.0054 0.5019
Mycobacterium tuberculosis Probable reductase 0.0058 0.0078 0.3361
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Schistosoma mansoni nuclear receptor 0.0011 0.0006 0.0015
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0009 0.0002 0.0002
Brugia malayi cathepsin F-like cysteine proteinase 0.0015 0.0012 0.0035
Brugia malayi hypothetical protein 0.0194 0.0288 0.0966
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0476 0.0721 0.0721
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0024 0.0026 0.1079
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0026 0.008
Brugia malayi hypothetical protein 0.0101 0.0144 0.0479
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0001 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0046 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Trypanosoma cruzi GMP reductase 0.0042 0.0054 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0031 0.1222
Echinococcus granulosus GPCR family 2 0.0151 0.0221 0.0219
Trichomonas vaginalis mercuric reductase, putative 0.0009 0.0002 0.0074
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0013 0.0008 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0007 0.0204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0018 0.0016 0.0049
Echinococcus granulosus orexin receptor type 2 0.0018 0.0016 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0026 0.008
Brugia malayi nuclear receptor RXR 0.0013 0.0008 0.0022
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0026 0.008
Schistosoma mansoni opsin-like receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0002 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0026 0.008
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Mycobacterium ulcerans lipase LipD 0.0024 0.0026 0.4637
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.004 0.005 0.0162
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0024 0.0027 0.1034
Echinococcus multilocularis neuropeptide receptor A26 0.0396 0.0597 0.0595
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0012 0.0008 0.0172
Echinococcus granulosus geminin 0.0205 0.0303 0.0302
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0042 0.0054 0.0175
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0012 0.0007 0.0858
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0045 0.0059 0.0192
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0037 0.012
Onchocerca volvulus 0.0046 0.0059 0.246
Brugia malayi hypothetical protein 0.0011 0.0006 0.0015
Mycobacterium tuberculosis Conserved protein 0.0024 0.0026 0.1079
Echinococcus multilocularis tryptophan hydroxylase 0.6513 1 1
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0023 0.0024 0.3937
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0016 0.0016
Echinococcus multilocularis survival motor neuron protein 1 0.0194 0.0288 0.0286
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0155 0.0227 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Trypanosoma cruzi cysteine proteinase, putative 0.0023 0.0025 0.0976
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0028 0.0031 0.0936
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0016 0.0016
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0009 0.0002 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.002 0.0019 0.0017
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0028 0.0031 0.0029
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0102
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0024 0.0027 0.1034
Onchocerca volvulus 0.0018 0.0016 0.0624
Echinococcus multilocularis ubiquitin specific protease 41 0.002 0.0019 0.0017
Onchocerca volvulus 0.0046 0.0059 0.246
Schistosoma mansoni tyrosine/tryptophan monooxygenase 0.1432 0.219 0.74
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0009 0.0002 0.0001
Onchocerca volvulus 0.0018 0.0016 0.0624
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0028 0.0031 0.01
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0028 0.0031 0.0029
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0012 0.0007 0.0193
Brugia malayi Pre-SET motif family protein 0.014 0.0204 0.0684
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0002 0.0058
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0026 0.008
Onchocerca volvulus Huntingtin homolog 0.0101 0.0144 0.6109
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0028 0.0031 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.002 0.0061
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0014 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0016 0.0014
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0008 0.0002 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0006 0.0189
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0016 0.0014
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0016 0.0049
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0097 0.0138 0.0136
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0016 0.0014
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0028 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) PDE1B protein 0.0028 0.0031 0.0031
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0026 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0156 0.0228 0.6813
Mycobacterium tuberculosis Probable dehydrogenase 0.0058 0.0078 0.3361
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0023 0.0025 0.0078
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0042 0.0054 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0016 0.0624
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0028 0.0031 0.116
Leishmania major phenylalanine-4-hydroxylase,phenylalanine-4-hydroxylase, putative 0.1432 0.219 1
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0026 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0006 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0059 0.1761
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0059 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0009 0.0002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0026 0.0024
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0016 0.0049
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0028 0.0031 0.0135
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0026 0.1025
Brugia malayi Cathepsin L-like precursor 0.0046 0.0059 0.0193
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0091
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0028 0.0031 0.01
Loa Loa (eye worm) hypothetical protein 0.0008 0.0002 0.0002
Trypanosoma cruzi trypanothione reductase, putative 0.0025 0.0028 0.1084
Plasmodium falciparum phosphodiesterase gamma, putative 0.0028 0.0031 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0008 0.0002 0.0058
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0024 0.0026 0.1079
Brugia malayi nuclear receptor NHR-88 0.0024 0.0026 0.008
Loa Loa (eye worm) hypothetical protein 0.003 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0009 0.0002 0.0021
Schistosoma mansoni amine GPCR 0.0018 0.0016 0.0049
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0026 0.1025
Mycobacterium ulcerans beta-lactamase 0.0024 0.0026 0.4637
Onchocerca volvulus 0.0016 0.0014 0.0516
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0009 0.0002 0.0021
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Schistosoma mansoni hypothetical protein 0.001 0.0005 0.001
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.002 0.002 0.3372
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0026 0.0026
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0009 0.0002 0.0021
Schistosoma mansoni hypothetical protein 0.0018 0.0016 0.0049
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Brugia malayi N-terminal motif family protein 0.0121 0.0176 0.0588
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Schistosoma mansoni biogenic amine receptor 0.0018 0.0016 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0008 0.0022
Brugia malayi Pre-SET motif family protein 0.002 0.002 0.0061
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) phosphatidylinositol 3 0.004 0.0051 0.0051
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.0006 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0026 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0007 0.0000099203 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0026 0.0783
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Trichomonas vaginalis esterase, putative 0.0024 0.0026 0.0783
Echinococcus granulosus biogenic amine 5HT receptor 0.0278 0.0417 0.0415
Echinococcus granulosus neuropeptide receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0028 0.0031 0.0029
Brugia malayi GMP reductase 0.0018 0.0016 0.0047
Schistosoma mansoni opsin-like receptor 0.0018 0.0016 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0031 0.0936
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0028 0.0031 0.1222
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0016 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0026 0.008
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0026 0.1025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0014 0.0012
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0016 0.0014
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0019 0.0019 0.0017
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0016 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus g protein coupled receptor 0.0018 0.0016 0.0014
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.0006 0.0004
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0025 0.0028 0.0026
Onchocerca volvulus 0.0024 0.0026 0.1048
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.002 0.0019 0.0059
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0226 0.0337 1
Leishmania major cathepsin L-like protease 0.0174 0.0256 0.116
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0016 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0037 0.012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus somatostatin receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Echinococcus granulosus fmrfamide receptor 0.0018 0.0016 0.0014
Schistosoma mansoni hypothetical protein 0.0205 0.0303 0.1019
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0028 0.0031 0.0031
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.0006 0.0015
Brugia malayi G-protein coupled receptor 0.0018 0.0016 0.0049
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0091
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0009 0.0002 0.0069
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0008 0.0002 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0026 0.1022
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0006 0.0004
Echinococcus granulosus ubiquitin specific protease 41 0.002 0.0019 0.0017
Trichomonas vaginalis set domain proteins, putative 0.0159 0.0234 0.6983
Brugia malayi Cathepsin L-like precursor 0.0046 0.0059 0.0193
Toxoplasma gondii IMP dehydrogenas 0.0042 0.0054 0.0175
Onchocerca volvulus 0.0018 0.0016 0.0624
Loa Loa (eye worm) hypothetical protein 0.0046 0.0059 0.0059
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0026 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Schistosoma mansoni neuropeptide receptor 0.0018 0.0016 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0225 0.0335 1
Schistosoma mansoni zinc finger protein 0.001 0.0005 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Echinococcus granulosus RUN 0.0016 0.0014 0.0012
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0042 0.0054 0.0052
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.002 0.0019 0.008
Onchocerca volvulus 0.0046 0.0059 0.246
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.002 0.002 0.0061
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0012 0.0007 0.0017
Schistosoma mansoni neuropeptide receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Leishmania major cysteine peptidase A (CPA) 0.0046 0.0059 0.0261
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0028 0.0031 0.1222
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0016 0.0014
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0008 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0002 0.0058
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0016 0.0014
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0009 0.0002 0.0091
Loa Loa (eye worm) cathepsin B 0.0008 0.0002 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0064 0.0087 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Echinococcus multilocularis geminin 0.0205 0.0303 0.0302
Brugia malayi hypothetical protein 0.0018 0.0016 0.0049
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0016 0.0014
Onchocerca volvulus 0.0046 0.0059 0.246
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Plasmodium vivax vivapain-2 0.0046 0.0059 0.0193
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0011 0.0006 0.0189
Schistosoma mansoni myosin xvIII 0.0018 0.0016 0.0049
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0046 0.0059 0.1761
Giardia lamblia hypothetical protein 0.0028 0.0031 0.0879
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Brugia malayi ecdysteroid receptor 0.0024 0.0026 0.008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0036 0.1071
Echinococcus multilocularis cathepsin L cysteine protease 0.0046 0.0059 0.0057
Loa Loa (eye worm) cysteine protease 0.0046 0.0059 0.0059
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0008 0.0002 0.0000057507
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0046 0.0059 0.0059
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0013 0.0008 0.0022
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0046 0.0059 0.0057
Schistosoma mansoni rab6-interacting 0.0016 0.0014 0.004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0026 0.008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0016 0.0049
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0016 0.0014
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0028 0.0031 0.0029
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0225 0.0335 0.1127
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0024 0.0027 0.0793
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0158 0.0233 0.9095
Trypanosoma cruzi cysteine peptidase, putative 0.0174 0.0256 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1356 0.2073 0.2071
Schistosoma mansoni biogenic amine receptor 0.0018 0.0016 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Plasmodium falciparum phosphodiesterase delta, putative 0.0028 0.0031 0.01
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0026 0.0783
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0199 0.0295 0.0295
Trichomonas vaginalis glucosylceramidase, putative 0.0225 0.0335 1
Entamoeba histolytica hypothetical protein 0.0019 0.0019 0.2913
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0028 0.0031 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni tyrosine 3-monooxygenase 0.1432 0.219 0.74
Entamoeba histolytica cysteine proteinase 1, putative 0.0023 0.0025 0.4054
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0025 0.4054
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0026 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0216 0.6449
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0016 0.0049
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0008 0.0002 0.0002
Toxoplasma gondii apocytochrome b, putative 0.1933 0.2959 1
Plasmodium vivax unspecified product 0.0015 0.0012 0.0035
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0026 0.008
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0016 0.0016
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0016 0.0624
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0028 0.0031 0.01
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0226 0.0337 0.1133
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0016 0.0014
Plasmodium falciparum LCCL domain-containing protein 0.0016 0.0014 0.004
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0159 0.0234 1
Brugia malayi Papain family cysteine protease containing protein 0.0023 0.0025 0.0078
Leishmania major hypothetical protein, conserved 0.0028 0.0031 0.0135
Plasmodium falciparum cytochrome b 0.1933 0.2959 1
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0026 0.0082
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0028 0.0031 0.0029
Brugia malayi hypothetical protein 0.0016 0.0014 0.004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Trichomonas vaginalis glutathione reductase, putative 0.0009 0.0002 0.0074
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Plasmodium vivax unspecified product 0.0023 0.0025 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0026 0.0026
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0018 0.0016 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0026 0.008
Toxoplasma gondii cytochrome b 0.1933 0.2959 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0037 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Onchocerca volvulus 0.0018 0.0016 0.0624
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0016 0.0014
Echinococcus granulosus serotonin receptor 0.0018 0.0016 0.0014
Entamoeba histolytica cysteine protease, putative 0.0023 0.0025 0.4054
Brugia malayi Bromodomain containing protein 0.0026 0.0028 0.0089
Mycobacterium tuberculosis Probable oxidoreductase 0.0064 0.0087 0.3801
Loa Loa (eye worm) hypothetical protein 0.1681 0.2573 0.2573
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0024 0.0026 0.0082
Onchocerca volvulus 0.0046 0.0059 0.246
Echinococcus granulosus survival motor neuron protein 1 0.0194 0.0288 0.0286
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.004 0.005 0.0162
Echinococcus granulosus hypothetical protein 0.0018 0.0016 0.0014
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0012 0.0007 0.0022
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0016 0.0049
Brugia malayi Cathepsin L-like cysteine proteinase 0.003 0.0036 0.0115
Echinococcus granulosus neuropeptide receptor A26 0.0396 0.0597 0.0595
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0016 0.0049
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0026 0.008
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0026 0.008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0016 0.0049
Echinococcus multilocularis cathepsin L cysteine protease 0.0046 0.0059 0.0057
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0008 0.0002 0.0073
Echinococcus multilocularis thioredoxin glutathione reductase 0.0025 0.0028 0.0026
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0016 0.0014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0016 0.0049
Onchocerca volvulus 0.0046 0.0059 0.246
Toxoplasma gondii aromatic amino acid hydrolase AAH2 0.1432 0.219 0.74
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0016 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0012 0.0007 0.0262
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0031 0.1222
Schistosoma mansoni hypothetical protein 0.0018 0.0016 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0003 0.0076
Schistosoma mansoni cytochrome b 0.1933 0.2959 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0011 0.0007 0.0016
Schistosoma mansoni loxhd1 0.0016 0.0014 0.004
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0031 0.0936
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Onchocerca volvulus Cathepsin L homolog 0.0046 0.0059 0.246
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.0031 0.0936
Mycobacterium tuberculosis Probable lipase LipE 0.0024 0.0026 0.1079
Trypanosoma cruzi ISWI complex protein 0.001 0.0005 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0023 0.0025 0.0912
Echinococcus granulosus cathepsin L cysteine protease 0.0023 0.0025 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.0006 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0006 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0009 0.0002 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0024 0.0026 0.0082
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.014 0.0204 0.0204
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0012 0.0007 0.0005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0016 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0019 0.0579
Trypanosoma brucei ISWI complex protein 0.001 0.0005 0.0111
Onchocerca volvulus 0.0024 0.0026 0.1048
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0019
Echinococcus multilocularis cathepsin L 0.0023 0.0025 0.0023
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0226 0.0337 0.0335
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.002 0.0019 0.3057
Loa Loa (eye worm) cytochrome b 0.1933 0.2959 0.2959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0174 0.0256 1
Brugia malayi Dopamine receptor 0.0018 0.0016 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0016 0.0049
Schistosoma mansoni hypothetical protein 0.0205 0.0303 0.1019
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0199 0.0295 0.0293
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0009 0.0002 0.5
Toxoplasma gondii ABC1 family protein 0.0024 0.0026 0.0082
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0012 0.0007 0.0858
Plasmodium vivax SET domain protein, putative 0.002 0.002 0.0061
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0026 0.008
Echinococcus multilocularis cysteine protease 0.0046 0.0059 0.0057
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0016 0.0049
Brugia malayi ecdysone receptor 0.0011 0.0006 0.0015
Brugia malayi Cathepsin L-like precursor 0.0015 0.0012 0.0035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0028 0.0031 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0031 0.0936
Loa Loa (eye worm) IMP dehydrogenase 1 0.0042 0.0054 0.0054

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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