Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0036 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.4311 | 0.7582 |
Toxoplasma gondii | FATC domain-containing protein | 0.0025 | 0.5761 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0019 | 0.2947 | 0.2947 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0019 | 0.2947 | 0.2947 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0019 | 0.2947 | 0.2947 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.5761 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.5639 | 0.5 |
Echinococcus granulosus | serine protein kinase ATM | 0.0025 | 0.5761 | 0.5761 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0025 | 0.5761 | 0.5761 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0019 | 0.2947 | 0.5097 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0019 | 0.2947 | 0.2947 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.5639 | 0.9568 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0019 | 0.2947 | 0.2947 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.5639 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0019 | 0.2947 | 0.4987 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.5761 | 0.3989 |
Brugia malayi | hypothetical protein | 0.0025 | 0.5639 | 0.4539 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0019 | 0.2947 | 0.2947 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.5639 | 1 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0019 | 0.2961 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0022 | 0.4311 | 0.4849 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0019 | 0.2961 | 0.0052 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.5761 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0019 | 0.2947 | 0.1167 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0019 | 0.2947 | 0.1167 |
Giardia lamblia | GTOR | 0.0019 | 0.2947 | 0.5 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0025 | 0.5761 | 0.5761 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0019 | 0.2947 | 0.5097 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.5639 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 1 | 1 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.5639 | 0.9784 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0025 | 0.5761 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0019 | 0.2947 | 0.4987 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0019 | 0.2947 | 0.4987 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0025 | 0.5761 | 0.4691 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.5639 | 0.9784 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.5639 | 0.9568 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0019 | 0.2947 | 0.4987 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.5639 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0019 | 0.2947 | 0.4987 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.