Detailed information for compound 649899

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 310.756 | Formula: C13H11ClN2O3S
  • H donors: 2 H acceptors: 3 LogP: 2.79 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)C=NNS(=O)(=O)c1ccc(cc1)Cl
  • InChi: 1S/C13H11ClN2O3S/c14-11-3-7-13(8-4-11)20(18,19)16-15-9-10-1-5-12(17)6-2-10/h1-9,16-17H/b15-9+
  • InChiKey: AKVWIIXTUAFFRW-OQLLNIDSSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus chromobox protein 1 0.0051 0.1429 0.1715
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.3019 0.3618
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0915 0.1097
Entamoeba histolytica hypothetical protein 0.0258 0.8312 0.8255
Brugia malayi CHD4 protein 0.0011 0.0097 0.0096
Echinococcus multilocularis zinc finger protein 0.002 0.0376 0.0448
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.1275 0.153
Schistosoma mansoni zinc finger protein 0.0011 0.0093 0.0112
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.3019 0.3618
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0341 0.0848
Mycobacterium ulcerans hypothetical protein 0.0029 0.0673 0.0792
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0915 0.0611
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0009 0.0018 0.0021
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0225 0.7214 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0099 0.3019 0.2952
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.1092 0.0794
Onchocerca volvulus 0.0019 0.0355 0.1125
Loa Loa (eye worm) oxidoreductase 0.0099 0.3019 0.4184
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.1275 0.3529
Brugia malayi NADH-dependent xylose reductase 0.0029 0.0673 0.0791
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0324 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1193 0.1431
Schistosoma mansoni ap endonuclease 0.0018 0.0324 0.039
Onchocerca volvulus 0.0019 0.0355 0.1125
Echinococcus multilocularis aldo keto reductase 0.0099 0.3019 0.3629
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0915 0.0611
Brugia malayi chromobox protein homolog 3 0.0029 0.0677 0.0795
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Schistosoma mansoni hypothetical protein 0.0166 0.5238 0.6302
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Schistosoma mansoni hypothetical protein 0.0015 0.0224 0.027
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0915 0.2811
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0324 0.0789
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0029 0.0673 0.0934
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0276 0.0383
Brugia malayi Doublecortin family protein 0.0019 0.0353 0.0405
Brugia malayi Muscleblind-like protein 0.0095 0.2871 0.3441
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0148 0.0186
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0673 0.0584
Schistosoma mansoni polycystin 1-related 0.0019 0.0353 0.0425
Echinococcus granulosus aldo keto reductase 0.0099 0.3019 0.3629
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Mycobacterium leprae Conserved hypothetical protein 0.007 0.2062 0.3415
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.4875 0.5856
Schistosoma mansoni methyl-cpg binding protein mbd 0.0013 0.0136 0.0164
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0019 0.0355 0.0492
Onchocerca volvulus 0.0019 0.0353 0.1119
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0099 0.3019 0.2952
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0097 0.0117
Echinococcus granulosus hypothetical protein 0.0099 0.3019 0.3629
Trypanosoma cruzi aldo-keto reductase 0.0099 0.3019 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0341 0.0848
Brugia malayi intermediate filament protein 0.0019 0.0355 0.0407
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0099 0.3019 1
Onchocerca volvulus 0.0023 0.0469 0.1505
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.3019 0.3618
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0011 0.0097 0.0112
Trypanosoma brucei unspecified product 0.0019 0.0341 0.0848
Plasmodium falciparum aldo-keto reductase, putative 0.0029 0.0673 0.4553
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Trichomonas vaginalis aldo/keto reductase, putative 0.0099 0.3019 0.2952
Mycobacterium tuberculosis Conserved protein 0.0029 0.0673 0.0792
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0341 0.0848
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.011 0.0015
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Schistosoma mansoni chromobox protein 0.0051 0.1429 0.1719
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0341 0.039
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0029 0.0673 0.1984
Brugia malayi hypothetical protein 0.0019 0.0353 0.0405
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0324 0.0789
Onchocerca volvulus 0.0099 0.3019 1
Echinococcus multilocularis aldo keto reductase 0.0099 0.3019 0.3629
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.1275 0.1192
Trichomonas vaginalis aldo/keto reductase, putative 0.0099 0.3019 0.2952
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0049 0.1362 0.1634
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0047 0.0036
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0915 0.1097
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0915 0.2811
Echinococcus granulosus lamin 0.0019 0.0355 0.0423
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Loa Loa (eye worm) hypothetical protein 0.0019 0.0353 0.049
Loa Loa (eye worm) hypothetical protein 0.0009 0.0025 0.0035
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0353 0.0421
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.1092 0.0794
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Schistosoma mansoni intermediate filament proteins 0.0019 0.0355 0.0427
Echinococcus multilocularis aldo keto reductase 0.0099 0.3019 0.3629
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.1092 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.1275 0.3529
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0341 0.0406
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.4875 0.5863
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.1193 0.1417
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Trypanosoma cruzi aldo/keto reductase, putative 0.0029 0.0673 0.1984
Schistosoma mansoni cpg binding protein 0.0028 0.0644 0.0774
Schistosoma mansoni hypothetical protein 0.0166 0.5238 0.6302
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1193 0.1435
Echinococcus granulosus aldo keto reductase 0.0099 0.3019 0.3629
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0029 0.0673 0.1297
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0309 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0673 0.0584
Schistosoma mansoni cpg binding protein 0.0031 0.0743 0.0894
Trichomonas vaginalis chromobox protein, putative 0.0051 0.1429 0.1347
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0749 0.0661
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0341 0.0018
Echinococcus granulosus intermediate filament protein 0.0019 0.0355 0.0423
Entamoeba histolytica hypothetical protein 0.0258 0.8312 0.8255
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0915 0.1097
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0915 0.0829
Loa Loa (eye worm) hypothetical protein 0.0037 0.0943 0.1307
Leishmania major DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0749 0.2439
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0324 0.0385
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0915 0.0829
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.1498 0.1799
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0915 0.1097
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0156 0.0188
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0915 0.1101
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Echinococcus multilocularis lamin 0.0019 0.0355 0.0423
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0207 0.0114
Echinococcus multilocularis aldo keto reductase 0.0099 0.3019 0.3629
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0324 0.0449
Loa Loa (eye worm) hypothetical protein 0.0099 0.3019 0.4184
Onchocerca volvulus 0.0029 0.0673 0.2186
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0396 0.0305
Entamoeba histolytica aldose reductase, putative 0.0099 0.3019 0.2785
Echinococcus multilocularis aldehyde reductase 0.007 0.2062 0.2478
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0151 0.474 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.1498 0.1799
Loa Loa (eye worm) hypothetical protein 0.0095 0.2871 0.398
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0324 0.0385
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0341 0.0411
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.4875 0.5865
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0341 0.0039
Leishmania major prostaglandin f synthase, putative 0.0099 0.3019 1
Leishmania major aldo-keto reductase-like protein 0.0099 0.3019 1
Leishmania major DNA polymerase eta, putative 0.0019 0.0341 0.0848
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1682 0.2024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0915 0.2811
Schistosoma mansoni rab6-interacting 0.0019 0.0353 0.0425
Brugia malayi hypothetical protein 0.0019 0.0353 0.0405
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0353 0.0421
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0012 0.011 0.0015
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Loa Loa (eye worm) heterochromatin protein 1 0.0051 0.1429 0.1981
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0341 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0843 0.1168
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0019
Loa Loa (eye worm) acetyltransferase 0.0155 0.4875 0.6757
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0915 0.2811
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0677 0.2196
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0353 0.0421
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0341 0.0411
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.4673 0.5621
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0915 0.1097
Loa Loa (eye worm) oxidoreductase 0.0099 0.3019 0.4184
Schistosoma mansoni loxhd1 0.0019 0.0353 0.0425
Brugia malayi Intermediate filament tail domain containing protein 0.0019 0.0355 0.0407
Brugia malayi Heterochromatin protein 1 0.0051 0.1429 0.1702
Loa Loa (eye worm) hypothetical protein 0.0052 0.1455 0.2016
Onchocerca volvulus 0.0019 0.0353 0.1119
Onchocerca volvulus 0.0099 0.3019 1
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0353 0.0309
Brugia malayi Bromodomain containing protein 0.0032 0.0783 0.0923
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0353 0.0383
Echinococcus granulosus dna polymerase kappa 0.0019 0.0341 0.0406
Entamoeba histolytica hypothetical protein 0.0258 0.8312 0.8255
Schistosoma mansoni hypothetical protein 0.0011 0.0093 0.0112
Loa Loa (eye worm) intermediate filament protein 0.0019 0.0355 0.0492
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0324 0.0789
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Loa Loa (eye worm) hypothetical protein 0.0019 0.0341 0.0473
Plasmodium falciparum aldehyde reductase, putative 0.0029 0.0673 0.4553
Toxoplasma gondii aldo-keto reductase 0.0029 0.0673 0.1297
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0258 0.8312 1
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0341 0.0848
Schistosoma mansoni lipoxygenase 0.0053 0.1498 0.1802
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0151 0.474 1
Echinococcus multilocularis muscleblind protein 1 0.0095 0.2871 0.3452
Onchocerca volvulus 0.0099 0.3019 1
Echinococcus multilocularis lamin dm0 0.0019 0.0355 0.0423
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0324 0.0231
Schistosoma mansoni zinc finger protein 0.002 0.0376 0.0452
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0029 0.0673 0.0806
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0749 0.0661
Echinococcus multilocularis voltage gated potassium channel subunit 0.0029 0.0673 0.0806
Echinococcus granulosus chromobox protein 1 0.0051 0.1429 0.1715
Toxoplasma gondii aldose reductase, putative 0.0099 0.3019 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0011 0.0097 0.0112
Schistosoma mansoni aldo-keto reductase 0.0099 0.3019 0.3632
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0207 0.0114
Trypanosoma brucei aldo-keto reductase, putative 0.0099 0.3019 1
Giardia lamblia DINP protein human, muc B family 0.0019 0.0341 0.0018
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0013 0.0136 0.0159
Brugia malayi hypothetical protein 0.0258 0.8312 1
Echinococcus granulosus zinc finger protein 0.002 0.0376 0.0448
Schistosoma mansoni methyl-cpg binding protein mbd 0.0013 0.0136 0.0164
Echinococcus granulosus histone lysine methyltransferase setb 0.0013 0.0156 0.0184
Plasmodium vivax aldehyde reductase, putative 0.0029 0.0673 0.3676
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Echinococcus granulosus voltage gated potassium channel subunit 0.0029 0.0673 0.0806
Schistosoma mansoni transcription factor LCR-F1 0.0258 0.8312 1
Trypanosoma brucei aldo/keto reductase, putative 0.0029 0.0673 0.1984
Echinococcus multilocularis chromobox protein 1 0.0051 0.1429 0.1715
Loa Loa (eye worm) oxidoreductase 0.0099 0.3019 0.4184
Brugia malayi follicle stimulating hormone receptor 0.0225 0.7214 0.8677
Echinococcus granulosus muscleblind protein 0.0095 0.2871 0.3452
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0341 0.0249
Schistosoma mansoni DNA polymerase eta 0.0019 0.0341 0.0411
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0341 0.0249
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0353 0.0421
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Echinococcus granulosus geminin 0.0166 0.5238 0.6301
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0207 0.0114
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0.06 0.0718
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0324 0.0369
Loa Loa (eye worm) hypothetical protein 0.0009 0.0013 0.0019
Schistosoma mansoni hypothetical protein 0.0019 0.0353 0.0425
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0029 0.0673 0.0791
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0341 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1193 0.1435
Loa Loa (eye worm) hypothetical protein 0.0028 0.066 0.0915
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0324 0.0231
Loa Loa (eye worm) hypothetical protein 0.0019 0.0343 0.0476
Schistosoma mansoni potassium channel beta 0.0029 0.0673 0.081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1193 0.1431
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1193 0.1431
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0018 0.0324 0.0385
Trypanosoma cruzi aldo/keto reductase, putative 0.0099 0.3019 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0309 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0207 0.0114
Schistosoma mansoni chromobox protein 0.0051 0.1429 0.1719
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Echinococcus multilocularis cpg binding protein 0.0031 0.0743 0.089
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0341 0.0848
Schistosoma mansoni rab6-interacting 0.0019 0.0353 0.0425
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0915 0.1097
Onchocerca volvulus 0.0028 0.0644 0.2086
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Entamoeba histolytica alcohol dehydrogenase, putative 0.0029 0.0673 0.0361
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0148 0.0186
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0156 0.0188
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Treponema pallidum fructose-bisphosphate aldolase 0.0309 1 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0099 0.3019 0.2952
Echinococcus multilocularis RUN 0.0019 0.0353 0.0421
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0341 0.0848
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0099 0.3019 0.5767
Brugia malayi Bromodomain containing protein 0.0061 0.1737 0.2074
Giardia lamblia Aldose reductase 0.0099 0.3019 0.2785
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0915 0.1083
Giardia lamblia Aldose reductase 0.0099 0.3019 0.2785
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0341 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0677 0.0588
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.3019 0.6102
Trichomonas vaginalis chromobox protein, putative 0.0051 0.1429 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0673 0.0584
Brugia malayi cytoplasmic intermediate filament protein 0.001 0.0059 0.005
Onchocerca volvulus 0.0099 0.3019 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.2871 0.398
Mycobacterium ulcerans oxidoreductase 0.0099 0.3019 0.6102
Trypanosoma brucei unspecified product 0.0013 0.0148 0.0186
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0341 0.0039
Trypanosoma brucei prostaglandin f synthase 0.0099 0.3019 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Echinococcus multilocularis musashi 0.0019 0.0355 0.0423
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0915 0.0829
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0018 0.0324 0.039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0355 0.0492
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0151 0.474 1
Echinococcus granulosus cpg binding protein 0.0031 0.0743 0.089
Loa Loa (eye worm) hypothetical protein 0.0013 0.0156 0.0217
Schistosoma mansoni cpg binding protein 0.0031 0.0743 0.0894
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0207 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0396 0.0305
Onchocerca volvulus 0.0099 0.3019 1
Schistosoma mansoni lamin 0.0019 0.0355 0.0427
Echinococcus multilocularis geminin 0.0166 0.5238 0.6301
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0029 0.0673 0.1297
Trichomonas vaginalis aldo-keto reductase, putative 0.0029 0.0673 0.0584
Trichomonas vaginalis aldo-keto reductase, putative 0.0099 0.3019 0.2952
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Echinococcus granulosus methyl CpG binding domain protein 2 0.0013 0.0136 0.0159
Loa Loa (eye worm) hypothetical protein 0.0019 0.0353 0.049
Schistosoma mansoni lamin 0.0019 0.0355 0.0427
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0207 0.0114
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.1275 0.1192
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0258 0.8312 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0915 0.1269
Echinococcus multilocularis dna polymerase eta 0.0019 0.0341 0.0406
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1193 0.1431
Echinococcus granulosus RUN 0.0019 0.0353 0.0421
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0341 0.0406
Onchocerca volvulus 0.0099 0.3019 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0148 0.0186
Schistosoma mansoni pol-related 0.0099 0.3019 0.3632
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0009 0.0025 0.0026
Entamoeba histolytica alcohol dehydrogenase, putative 0.0029 0.0673 0.0361
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0353 0.0421
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0207 0.0114
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0029 0.0673 0.3676
Schistosoma mansoni hypothetical protein 0.0258 0.8312 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0309 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1193 0.1435
Entamoeba histolytica hypothetical protein 0.0258 0.8312 0.8255
Schistosoma mansoni aldo-keto reductase 0.0099 0.3019 0.3632
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0677 0.0588
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0049 0.1362 0.1634
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.1655 0.4941
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0099 0.3019 0.2952
Loa Loa (eye worm) oxidoreductase 0.0099 0.3019 0.4184
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.1275 1
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0029 0.0673 0.0584
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0013 0.0156 0.0184
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.001 0.0059 0.0082
Brugia malayi PHD-finger family protein 0.0024 0.0507 0.059
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0341 0.0406
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0099 0.3019 0.3629
Loa Loa (eye worm) hypothetical protein 0.0029 0.0677 0.0938
Echinococcus multilocularis chromobox protein 1 0.0051 0.1429 0.1715
Schistosoma mansoni bromodomain containing protein 0.0052 0.145 0.1744
Loa Loa (eye worm) CHromoDomain protein family member 0.0011 0.0097 0.0135
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0341 0.039
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0353 0.0421
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0099 0.3019 0.3618
Loa Loa (eye worm) hypothetical protein 0.0023 0.0469 0.0651
Echinococcus granulosus dna polymerase eta 0.0019 0.0341 0.0406
Entamoeba histolytica aldose reductase, putative 0.0099 0.3019 0.2785
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0099 0.3019 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0018 0.0324 0.0385
Schistosoma mansoni ap endonuclease 0.0018 0.0324 0.039
Loa Loa (eye worm) PHD-finger family protein 0.0015 0.0224 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0009 0.0025 0.0026
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0099 0.3019 0.3629
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0324 0.0789
Echinococcus multilocularis muscleblind protein 0.0095 0.2871 0.3452
Loa Loa (eye worm) oxidoreductase 0.0099 0.3019 0.4184
Brugia malayi CXXC zinc finger family protein 0.0028 0.0644 0.0755
Echinococcus granulosus aldo keto reductase 0.0099 0.3019 0.3629
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0.06 0.0718
Trypanosoma brucei unspecified product 0.0013 0.0148 0.0186
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0207 0.0114
Schistosoma mansoni lipoxygenase 0.0019 0.0353 0.0425
Echinococcus granulosus aldehyde reductase 0.007 0.2062 0.2478
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.1193 0.1653
Entamoeba histolytica aldose reductase, putative 0.0099 0.3019 0.2785
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0915 0.1101
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0644 0.0892
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0353 0.049
Echinococcus granulosus lamin dm0 0.0019 0.0355 0.0423
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0341 0.0848

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.