Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0928 | 0.705 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0928 | 0.705 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0109 | 0.1147 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0033 | 0.004 |
Onchocerca volvulus | 0.0119 | 0.0821 | 0.8915 | |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0033 | 0.004 |
Onchocerca volvulus | 0.0048 | 0.0278 | 0.2443 | |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0107 | 0.0735 | 0.2032 |
Brugia malayi | Carboxylesterase family protein | 0.0119 | 0.0821 | 0.1165 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0033 | 0.004 |
Onchocerca volvulus | 0.013 | 0.0912 | 1 | |
Echinococcus multilocularis | disco interacting protein 2 | 0.0025 | 0.0097 | 0.0174 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.013 | 0.0912 | 0.1288 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0268 | 0.0439 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0033 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0468 | 0.0619 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0073 | 0.0468 | 0.0664 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0033 | 0.0054 |
Leishmania major | trypanothione reductase | 0.0047 | 0.027 | 0.0377 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0107 | 0.0735 | 0.2032 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0107 | 0.0735 | 0.7433 |
Echinococcus granulosus | acetylcholinesterase | 0.0702 | 0.5313 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0033 | 0.004 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.013 | 0.0912 | 1 |
Onchocerca volvulus | 0.0119 | 0.0821 | 0.8915 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0033 | 0.004 |
Mycobacterium ulcerans | lipase LipD | 0.0073 | 0.0468 | 0.0619 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0468 | 0.0619 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0067 | 0.0427 | 0.0796 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0047 | 0.027 | 0.0338 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0268 | 0.0197 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0468 | 0.1258 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.027 | 0.2926 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0268 | 0.0496 |
Plasmodium vivax | polyprenol reductase, putative | 0.013 | 0.0912 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0033 | 0.0314 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0144 | 0.1016 | 0.1686 |
Mycobacterium ulcerans | beta-lactamase | 0.0073 | 0.0468 | 0.0619 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.013 | 0.0912 | 0.1294 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0073 | 0.0468 | 0.0872 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1054 | 0.0988 |
Entamoeba histolytica | hypothetical protein | 0.013 | 0.0912 | 0.1288 |
Onchocerca volvulus | 0.0073 | 0.0468 | 0.4707 | |
Echinococcus multilocularis | cpg binding protein | 0.0021 | 0.0073 | 0.0128 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0109 | 0.0108 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0107 | 0.0735 | 0.2032 |
Loa Loa (eye worm) | carboxylesterase | 0.0119 | 0.0821 | 0.0754 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0468 | 0.0398 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0109 | 0.0148 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0468 | 0.1258 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0465 | 0.3486 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0119 | 0.0821 | 0.1361 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0073 | 0.0468 | 0.1258 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0912 | 0.0846 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0702 | 0.5313 | 0.5279 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0468 | 0.1258 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.013 | 0.0912 | 0.1709 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0109 | 0.0148 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0033 | 0.0054 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.013 | 0.0912 | 0.1253 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0067 | 0.0427 | 0.0796 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0073 | 0.0468 | 0.0657 |
Loa Loa (eye worm) | beta-lactamase | 0.0073 | 0.0468 | 0.0398 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0119 | 0.0821 | 0.1537 |
Onchocerca volvulus | 0.0104 | 0.0711 | 0.76 | |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0109 | 0.0148 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0073 | 0.0468 | 0.1258 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0047 | 0.027 | 0.05 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0073 | 0.0468 | 0.1258 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0067 | 0.0427 | 0.0796 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0468 | 0.0657 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0067 | 0.0427 | 0.0796 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0268 | 0.0496 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0119 | 0.0821 | 0.2281 |
Brugia malayi | Thioredoxin reductase | 0.0047 | 0.027 | 0.0384 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0033 | 0.0047 |
Trichomonas vaginalis | conserved hypothetical protein | 0.013 | 0.0912 | 0.1253 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1054 | 0.0988 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0119 | 0.0821 | 0.1537 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0268 | 0.0439 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0928 | 0.705 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0067 | 0.0427 | 0.4225 |
Trypanosoma cruzi | 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative | 0.0104 | 0.0711 | 0.0965 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.013 | 0.0912 | 0.1288 |
Echinococcus multilocularis | muscleblind protein | 0.0149 | 0.1054 | 0.1975 |
Onchocerca volvulus | 0.0073 | 0.0468 | 0.4707 | |
Leishmania major | hypothetical protein, conserved | 0.0104 | 0.0711 | 0.1002 |
Schistosoma mansoni | Lamin B receptor (ERG24) | 0.0135 | 0.0945 | 0.1567 |
Echinococcus granulosus | cpg binding protein | 0.0021 | 0.0073 | 0.0128 |
Trichomonas vaginalis | conserved hypothetical protein | 0.013 | 0.0912 | 0.1253 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0073 | 0.0468 | 0.1258 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.013 | 0.0912 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0468 | 0.0664 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0119 | 0.0821 | 0.1123 |
Toxoplasma gondii | thioredoxin reductase | 0.0047 | 0.027 | 0.0377 |
Schistosoma mansoni | cpg binding protein | 0.0021 | 0.0073 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0119 | 0.0821 | 0.1537 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0268 | 0.0496 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0073 | 0.0468 | 0.0398 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0073 | 0.0468 | 0.1258 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0109 | 0.0037 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.013 | 0.0912 | 0.1288 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0119 | 0.0827 | 0.23 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0119 | 0.0827 | 0.23 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0067 | 0.0427 | 0.0796 |
Brugia malayi | glutathione reductase | 0.0047 | 0.027 | 0.0384 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0119 | 0.0821 | 0.1537 |
Trypanosoma cruzi | C-14 sterol reductase, putative | 0.0135 | 0.0945 | 0.1299 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0268 | 0.0496 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0702 | 0.5313 | 0.885 |
Trypanosoma cruzi | Emopamil binding protein, putative | 0.0104 | 0.0711 | 0.0965 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0033 | 0.004 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0047 | 0.027 | 0.0686 |
Schistosoma mansoni | cpg binding protein | 0.0021 | 0.0073 | 0.0113 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0067 | 0.0427 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0702 | 0.5313 | 0.5279 |
Plasmodium falciparum | polyprenol reductase, putative | 0.013 | 0.0912 | 1 |
Onchocerca volvulus | 0.0119 | 0.0821 | 0.8915 | |
Leishmania major | 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative | 0.0104 | 0.0711 | 0.1002 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0119 | 0.0821 | 0.1361 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.0289 | 0.0218 |
Trypanosoma cruzi | Emopamil binding protein, putative | 0.0104 | 0.0711 | 0.0965 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.013 | 0.0912 | 1 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.013 | 0.0912 | 0.1288 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0278 | 0.0394 |
Brugia malayi | Carboxylesterase family protein | 0.0702 | 0.5313 | 0.7537 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0119 | 0.0821 | 0.1537 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0109 | 0.1147 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0047 | 0.027 | 0.2926 |
Loa Loa (eye worm) | hypothetical protein | 0.0702 | 0.5313 | 0.5279 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0468 | 0.0398 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.013 | 0.0912 | 0.1288 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0033 | 0.0047 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0468 | 0.0619 |
Echinococcus granulosus | muscleblind protein | 0.0149 | 0.1054 | 0.1975 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0468 | 0.0398 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0109 | 0.0155 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0109 | 0.0108 |
Brugia malayi | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0.0928 | 0.705 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0033 | 0.0314 |
Mycobacterium ulcerans | hypothetical protein | 0.0928 | 0.705 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0278 | 0.0455 |
Toxoplasma gondii | hypothetical protein | 0.0054 | 0.0324 | 0.0453 |
Brugia malayi | Carboxylesterase family protein | 0.0119 | 0.0821 | 0.1165 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.013 | 0.0912 | 0.1709 |
Onchocerca volvulus | 0.0025 | 0.0097 | 0.0294 | |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0468 | 0.0664 |
Trypanosoma cruzi | 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative | 0.0104 | 0.0711 | 0.0965 |
Loa Loa (eye worm) | carboxylesterase | 0.0702 | 0.5313 | 0.5279 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0033 | 0.004 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0119 | 0.0821 | 0.1361 |
Brugia malayi | Carboxylesterase family protein | 0.0119 | 0.0821 | 0.1165 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0427 | 0.0357 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0033 | 0.0314 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0073 | 0.0468 | 0.0619 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0928 | 0.705 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0119 | 0.0821 | 0.1361 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0033 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0119 | 0.0821 | 0.1361 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0033 | 0.0314 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0016 | 0.0033 | 0.5 |
Trypanosoma cruzi | C-14 sterol reductase, putative | 0.0135 | 0.0945 | 0.1299 |
Brugia malayi | Carboxylesterase family protein | 0.0702 | 0.5313 | 0.7537 |
Schistosoma mansoni | disco-interacting protein 2 (dip2) | 0.0025 | 0.0097 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.027 | 0.2926 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0073 | 0.0468 | 0.1258 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0119 | 0.0827 | 0.23 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0033 | 0.5 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.013 | 0.0912 | 0.1253 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0268 | 0.0381 |
Echinococcus multilocularis | acetylcholinesterase | 0.0702 | 0.5313 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0468 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0468 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.1722 | 0.1661 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0109 | 0.1147 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0928 | 0.705 | 1 |
Trypanosoma cruzi | sterol C-24 reductase, putative | 0.0135 | 0.0945 | 0.1299 |
Onchocerca volvulus | 0.0119 | 0.0821 | 0.8915 | |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.013 | 0.0912 | 0.1253 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0928 | 0.705 | 1 |
Schistosoma mansoni | gliotactin | 0.0119 | 0.0821 | 0.1361 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.1722 | 0.3234 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0928 | 0.705 | 1 |
Brugia malayi | Disco-interacting protein 2 homolog | 0.0025 | 0.0097 | 0.0138 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0119 | 0.0821 | 0.1123 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0702 | 0.5313 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0107 | 0.0735 | 0.2032 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.013 | 0.0912 | 0.1709 |
Echinococcus multilocularis | acetylcholinesterase | 0.0702 | 0.5313 | 1 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0928 | 0.705 | 1 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.013 | 0.0912 | 0.1709 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0278 | 0.0455 |
Trypanosoma cruzi | sterol C-24 reductase, putative | 0.0135 | 0.0945 | 0.1299 |
Echinococcus granulosus | disco interacting protein 2 | 0.0025 | 0.0097 | 0.0174 |
Brugia malayi | Carboxylesterase family protein | 0.0119 | 0.0821 | 0.1165 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.1722 | 0.3234 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.013 | 0.0912 | 0.1513 |
Echinococcus granulosus | lamin b receptor | 0.0135 | 0.0945 | 0.1771 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0097 | 0.0025 |
Loa Loa (eye worm) | glutathione reductase | 0.0047 | 0.027 | 0.0199 |
Leishmania major | C-14 sterol reductase, putative | 0.0135 | 0.0945 | 0.1334 |
Mycobacterium ulcerans | hypothetical protein | 0.0073 | 0.0468 | 0.0619 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0468 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0912 | 0.0846 |
Schistosoma mansoni | intracisternal A-particle retropepsin (A02 family) | 0.0792 | 0.6003 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0038 | 0.0053 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0268 | 0.0439 |
Trypanosoma brucei | trypanothione reductase | 0.0047 | 0.027 | 0.0377 |
Trypanosoma brucei | Emopamil binding protein, putative | 0.0104 | 0.0711 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0928 | 0.705 | 0.7028 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.013 | 0.0912 | 0.1513 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0468 | 0.0772 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0047 | 0.027 | 0.05 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.0289 | 0.0409 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0073 | 0.0468 | 0.1258 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0149 | 0.1054 | 0.1975 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0119 | 0.0821 | 0.1361 |
Brugia malayi | CXXC zinc finger family protein | 0.0021 | 0.0073 | 0.0103 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0073 | 0.0468 | 0.0619 |
Leishmania major | sterol C-24 reductase, putative | 0.0135 | 0.0945 | 0.1334 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0047 | 0.027 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0468 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0468 | 0.0398 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0119 | 0.0821 | 0.2281 |
Plasmodium vivax | hypothetical protein, conserved | 0.0073 | 0.0468 | 0.5102 |
Schistosoma mansoni | cpg binding protein | 0.0021 | 0.0073 | 0.0113 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0119 | 0.0821 | 0.1123 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0033 | 0.0314 |
Echinococcus granulosus | carboxylesterase 5A | 0.0702 | 0.5313 | 1 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0033 | 0.004 |
Echinococcus granulosus | acetylcholinesterase | 0.0702 | 0.5313 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0073 | 0.0468 | 0.0657 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0033 | 0.004 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0119 | 0.0827 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0119 | 0.0821 | 0.2281 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Onchocerca volvulus | 0.0119 | 0.0821 | 0.8915 | |
Echinococcus granulosus | neuroligin | 0.0119 | 0.0821 | 0.1537 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0468 | 0.0619 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0067 | 0.0427 | 0.0606 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0073 | 0.0468 | 0.0872 |
Plasmodium vivax | glutathione reductase, putative | 0.0047 | 0.027 | 0.2926 |
Trypanosoma brucei | C-14 sterol reductase, putative | 0.0135 | 0.0945 | 0.1334 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0107 | 0.0735 | 0.2032 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0067 | 0.0427 | 0.0357 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0928 | 0.705 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.013 | 0.0912 | 0.1253 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0821 | 0.0754 |
Echinococcus multilocularis | neuroligin | 0.0119 | 0.0821 | 0.1537 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0119 | 0.0821 | 0.1537 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0033 | 0.004 |
Echinococcus multilocularis | lamin b receptor | 0.0135 | 0.0945 | 0.1771 |
Loa Loa (eye worm) | carboxylesterase | 0.0119 | 0.0821 | 0.0754 |
Brugia malayi | beta-lactamase | 0.0073 | 0.0468 | 0.0664 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.013 | 0.0912 | 0.1253 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0033 | 0.0314 |
Onchocerca volvulus | 0.0073 | 0.0468 | 0.4707 | |
Trichomonas vaginalis | esterase, putative | 0.0073 | 0.0468 | 0.0619 |
Brugia malayi | Muscleblind-like protein | 0.0149 | 0.1054 | 0.1494 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0821 | 0.1165 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0468 | 0.0619 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0107 | 0.0735 | 0.2032 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0054 | 0.0324 | 0.3519 |
Brugia malayi | hypothetical protein | 0.0236 | 0.1722 | 0.2442 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0468 | 0.0619 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.