Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.1019 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0172 | 0.11 | 0.11 |
Onchocerca volvulus | 0.0172 | 0.11 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.1019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1019 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0172 | 0.11 | 0.11 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0172 | 0.11 | 0.11 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0172 | 0.11 | 0.11 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0172 | 0.11 | 0.5 |
Echinococcus multilocularis | geminin | 0.0188 | 0.127 | 0.127 |
Schistosoma mansoni | acetylcholinesterase | 0.0172 | 0.11 | 0.11 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.127 | 0.127 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0172 | 0.11 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1019 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0172 | 0.11 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0172 | 0.11 | 0.11 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0172 | 0.11 | 0.11 |
Onchocerca volvulus | 0.0172 | 0.11 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.1019 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0172 | 0.11 | 0.11 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0172 | 0.11 | 0.11 |
Onchocerca volvulus | 0.0172 | 0.11 | 0.5 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0172 | 0.11 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0172 | 0.11 | 0.11 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0172 | 0.11 | 1 |
Schistosoma mansoni | gliotactin | 0.0172 | 0.11 | 0.11 |
Loa Loa (eye worm) | hypothetical protein | 0.1019 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0172 | 0.11 | 0.11 |
Schistosoma mansoni | hypothetical protein | 0.0188 | 0.127 | 0.127 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1019 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0188 | 0.127 | 0.127 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1019 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1019 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1019 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0172 | 0.11 | 1 |
Onchocerca volvulus | 0.0172 | 0.11 | 0.5 | |
Echinococcus multilocularis | neuroligin | 0.0172 | 0.11 | 0.11 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1019 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0172 | 0.11 | 0.11 |
Brugia malayi | Carboxylesterase family protein | 0.1019 | 1 | 1 |
Onchocerca volvulus | 0.0172 | 0.11 | 0.5 | |
Echinococcus granulosus | neuroligin | 0.0172 | 0.11 | 0.11 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.