Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0077 | 0.0856 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0165 | 0.0275 |
Brugia malayi | Carboxylesterase family protein | 0.0077 | 0.0856 | 0.1426 |
Loa Loa (eye worm) | hypothetical protein | 0.0455 | 0.6001 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Echinococcus multilocularis | acetylcholinesterase | 0.0455 | 0.6001 | 0.5934 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0077 | 0.0856 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0455 | 0.6001 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0077 | 0.0856 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0455 | 0.6001 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0455 | 0.6001 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0165 | 0.0275 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0165 | 0.0275 |
Echinococcus granulosus | neuroligin | 0.0077 | 0.0856 | 0.0702 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0749 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0455 | 0.6001 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Echinococcus granulosus | acetylcholinesterase | 0.0455 | 0.6001 | 0.5934 |
Brugia malayi | Carboxylesterase family protein | 0.0077 | 0.0856 | 0.1426 |
Echinococcus multilocularis | acetylcholinesterase | 0.0455 | 0.6001 | 0.5934 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0455 | 0.6001 | 0.5934 |
Echinococcus granulosus | carboxylesterase 5A | 0.0455 | 0.6001 | 0.5934 |
Brugia malayi | Carboxylesterase family protein | 0.0077 | 0.0856 | 0.1426 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0455 | 0.6001 | 0.5934 |
Onchocerca volvulus | 0.0077 | 0.0856 | 1 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0077 | 0.0856 | 0.5 |
Onchocerca volvulus | 0.0077 | 0.0856 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0455 | 0.6001 | 1 |
Onchocerca volvulus | 0.0077 | 0.0856 | 1 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Brugia malayi | Carboxylesterase family protein | 0.0077 | 0.0856 | 0.1426 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0077 | 0.0856 | 0.5 |
Echinococcus multilocularis | neuroligin | 0.0077 | 0.0856 | 0.0702 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Schistosoma mansoni | gliotactin | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.0264 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0077 | 0.0856 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0077 | 0.0856 | 0.0702 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0749 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0455 | 0.6001 | 0.5934 |
Onchocerca volvulus | 0.0077 | 0.0856 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Loa Loa (eye worm) | carboxylesterase | 0.0077 | 0.0856 | 0.1426 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0856 | 0.1426 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Onchocerca volvulus | 0.0077 | 0.0856 | 1 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | carboxylesterase | 0.0077 | 0.0856 | 0.1426 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0165 | 0.0275 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0077 | 0.0856 | 0.0702 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0165 | 0.0275 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.