Detailed information for compound 652732

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 459.534 | Formula: C28H29NO5
  • H donors: 1 H acceptors: 2 LogP: 4.44 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(COC(=C1C(=NC2=C(C1c1ccc3c(c1)OCO3)C(=O)CC(C2)c1ccccc1)C)O)C
  • InChi: 1S/C28H29NO5/c1-16(2)14-32-28(31)25-17(3)29-21-11-20(18-7-5-4-6-8-18)12-22(30)27(21)26(25)19-9-10-23-24(13-19)34-15-33-23/h4-10,13,16,20,26,31H,11-12,14-15H2,1-3H3
  • InChiKey: BUMCGFGVVDZOAE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cyclin l 0.0015 0.0006 0.0008
Giardia lamblia Beta tubulin 0.0472 0.1946 1
Brugia malayi cell division control protein 2 homolog 0.009 0.0322 0.0886
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0012 0.0028
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0645 0.2679 0.7358
Trichomonas vaginalis tubulin epsilon chain, putative 0.0472 0.1946 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0012 0.0028
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0144 0.0133
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0234 0.0936 0.1294
Schistosoma mansoni cyclin B3 0.0063 0.021 0.029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0645 0.2679 0.3703
Schistosoma mansoni biogenic amine receptor 0.0645 0.2679 0.3703
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0645 0.2679 0.3703
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0012 0.0028
Onchocerca volvulus 0.0645 0.2679 1
Onchocerca volvulus 0.0026 0.0053 0.0177
Loa Loa (eye worm) endoprotease bli-4 0.0148 0.0567 0.1558
Plasmodium vivax protein kinase Crk2 0.009 0.0322 0.1631
Schistosoma mansoni tubulin subunit beta 0.0472 0.1946 0.2689
Schistosoma mansoni hypothetical protein 0.0645 0.2679 0.3703
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.009 0.0322 0.0886
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0483 0.0667
Trichomonas vaginalis cyclins, putative 0.0126 0.0477 0.2425
Echinococcus granulosus tubulin subunit beta 0.0472 0.1946 0.2689
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0645 0.2679 0.3703
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Onchocerca volvulus Neuropeptide F receptor homolog 0.0645 0.2679 1
Echinococcus granulosus cyclin G2 0.0015 0.0006 0.0008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0052 0.0072
Echinococcus granulosus neuropeptide receptor 0.0645 0.2679 0.3703
Echinococcus granulosus G1:S specific cyclin D1 0.0015 0.0006 0.0008
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0099 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0052 0.0144
Brugia malayi Tachykinin-like peptides receptor 99D 0.0645 0.2679 0.7358
Brugia malayi G-protein coupled receptor 0.0645 0.2679 0.7358
Leishmania major DNA polymerase kappa, putative 0.0019 0.0024 0.0092
Brugia malayi G protein-coupled receptor F59B2.13 0.0645 0.2679 0.7358
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0052 0.0072
Loa Loa (eye worm) TYRA-2 protein 0.0645 0.2679 0.7358
Plasmodium falciparum plasmepsin IV 0.0249 0.0999 0.5118
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0495 0.2041 0.2821
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0012 0.0017
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0062 0.0203 0.0281
Schistosoma mansoni cyclin B 0.0126 0.0477 0.0659
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0278 0.0764
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0052 0.0072
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0059 0.0191 0.0966
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Plasmodium vivax aspartyl protease, putative 0.0059 0.0191 0.0955
Toxoplasma gondii beta-tubulin, putative 0.0472 0.1946 1
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0249 0.0999 0.1381
Echinococcus granulosus tubulin beta 1 chain 0.0472 0.1946 0.2689
Schistosoma mansoni thyroid hormone receptor 0.0154 0.0594 0.0821
Echinococcus granulosus cyclin G2 0.0015 0.0006 0.0008
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0645 0.2679 0.3703
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0062 0.0203 0.1016
Echinococcus granulosus cyclins 0.0015 0.0006 0.0008
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0104 0.0382 0.0528
Echinococcus multilocularis sex peptide receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0052 0.0072
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus tm gpcr rhodopsin 0.0645 0.2679 0.3703
Schistosoma mansoni hypothetical protein 0.0015 0.0006 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0099 0.0478
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Leishmania major beta tubulin 0.0472 0.1946 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0099 0.0478
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0145 0.0133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0052 0.0144
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0712 0.1956
Echinococcus multilocularis musashi 0.0026 0.0053 0.0074
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0062 0.0203 0.0558
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni furin-1 (S08 family) 0.0064 0.0214 0.0295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Schistosoma mansoni cyclins 0.0063 0.021 0.029
Loa Loa (eye worm) tubulin beta chain 0.0472 0.1946 0.5344
Toxoplasma gondii aspartyl protease 0.0059 0.0191 0.0966
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0024 0.0033
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0645 0.2679 0.7358
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Echinococcus granulosus cyclins 0.0063 0.021 0.029
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0001 0.0004
Brugia malayi Eukaryotic aspartyl protease family protein 0.0059 0.0191 0.0525
Echinococcus granulosus neuropeptide Y receptor 0.0645 0.2679 0.3703
Giardia lamblia Beta tubulin 0.0472 0.1946 1
Echinococcus granulosus neuropeptide Y receptor 0.0645 0.2679 0.3703
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0645 0.2679 0.3703
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Plasmodium vivax aspartyl protease, putative 0.0059 0.0191 0.0955
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0052 0.0144
Onchocerca volvulus 0.0059 0.0191 0.0693
Leishmania major beta tubulin 0.0472 0.1946 1
Brugia malayi follicle stimulating hormone receptor 0.0872 0.3641 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0126 0.0477 0.1309
Echinococcus multilocularis G-protein coupled receptor, putative 0.0645 0.2679 0.3703
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0006 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Loa Loa (eye worm) hypothetical protein 0.0126 0.0477 0.1309
Leishmania major beta tubulin 0.0472 0.1946 1
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0148 0.0567 0.0784
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Schistosoma mansoni amine GPCR 0.0645 0.2679 0.3703
Plasmodium vivax aspartyl proteinase, putative 0.0249 0.0999 0.5118
Echinococcus granulosus cyclin dependent kinase 1 0.009 0.0322 0.0446
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Loa Loa (eye worm) aspartyl protease 6 0.0059 0.0191 0.0525
Plasmodium falciparum plasmepsin VII 0.0059 0.0191 0.0955
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0104 0.0382 0.0528
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0012 0.0028
Brugia malayi putative neuropeptide receptor 0.0645 0.2679 0.7358
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0004 0.0005
Plasmodium falciparum plasmepsin VIII, putative 0.0059 0.0191 0.0955
Echinococcus multilocularis lamin 0.0026 0.0053 0.0074
Leishmania major beta tubulin 0.0472 0.1946 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0092
Trichomonas vaginalis cyclin B, putative 0.0126 0.0477 0.2425
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0052 0.0072
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0322 0.1631
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0052 0.0144
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Schistosoma mansoni hypothetical protein 0.0645 0.2679 0.3703
Schistosoma mansoni opsin-like receptor 0.0645 0.2679 0.3703
Brugia malayi hypothetical protein 0.0059 0.0191 0.0525
Trypanosoma brucei beta tubulin 0.0472 0.1946 0.6065
Onchocerca volvulus Glucosylceramidase homolog 0.0167 0.065 0.241
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.237 1 1
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Onchocerca volvulus 0.0645 0.2679 1
Leishmania major beta tubulin 0.0472 0.1946 1
Plasmodium falciparum cyclin 0.0063 0.021 0.105
Brugia malayi intermediate filament protein 0.0026 0.0053 0.0147
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0006 0.0017
Echinococcus multilocularis Tubulin beta 2C chain 0.0472 0.1946 0.2689
Echinococcus granulosus peptide allatostatin:somatostatin 0.0645 0.2679 0.3703
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0062 0.0203 0.1016
Schistosoma mansoni tubulin subunit beta 0.0472 0.1946 0.2689
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.0052 0.0173
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0472 0.1946 0.2689
Onchocerca volvulus 0.0645 0.2679 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0472 0.1946 0.2689
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0645 0.2679 0.3703
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.0052 0.0173
Giardia lamblia Hypothetical protein 0.0063 0.021 0.105
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0145 0.0714
Schistosoma mansoni amine GPCR 0.0645 0.2679 0.3703
Echinococcus multilocularis neuropeptide receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) neuropeptide F receptor 0.0645 0.2679 0.7358
Brugia malayi proprotein convertase 2 0.0093 0.0335 0.0919
Schistosoma mansoni protein kinase 0.0495 0.2041 0.2821
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0012 0.0028
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0645 0.2679 0.7358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0712 0.0984
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi ORL1-like opioid receptor 0.0645 0.2679 0.7358
Plasmodium falciparum protein kinase 5 0.009 0.0322 0.1631
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.009 0.0322 0.1631
Echinococcus granulosus somatostatin receptor 0.0645 0.2679 0.3703
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0645 0.2679 0.3703
Echinococcus multilocularis citrate lyase subunit beta protein 0.0048 0.0145 0.02
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0645 0.2679 0.3703
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0712 0.1956
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0249 0.0999 0.2743
Plasmodium falciparum calcium-dependent protein kinase 1 0.0062 0.0203 0.1016
Schistosoma mansoni adenoreceptor 0.0645 0.2679 0.3703
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0455 0.0444
Echinococcus multilocularis cyclin G2 0.0015 0.0006 0.0008
Schistosoma mansoni neuropeptide receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0645 0.2679 0.3703
Leishmania major beta tubulin 0.0472 0.1946 1
Brugia malayi Dopamine receptor 0.0645 0.2679 0.7358
Schistosoma mansoni hypothetical protein 0.0645 0.2679 0.3703
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0099 0.029
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0024 0.0033
Schistosoma mansoni cyclin k 0.0015 0.0006 0.0008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0024 0.0092
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0024 0.0066
Schistosoma mansoni hypothetical protein 0.0128 0.0483 0.0667
Echinococcus granulosus G protein coupled receptor 139 0.0645 0.2679 0.3703
Entamoeba histolytica cyclin, putative 0.0063 0.021 0.105
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0195 0.027
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0019 0.0026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Plasmodium vivax aspartyl proteinase, putative 0.0059 0.0191 0.0955
Schistosoma mansoni neuropeptide receptor 0.1719 0.7234 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0645 0.2679 0.3703
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.009 0.0322 0.1641
Leishmania major beta tubulin 0.0472 0.1946 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0645 0.2679 0.3703
Schistosoma mansoni cyclin G2 0.0015 0.0006 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0322 0.1631
Giardia lamblia Kinase, CMGC CDK 0.009 0.0322 0.1631
Echinococcus multilocularis lamin dm0 0.0026 0.0053 0.0074
Echinococcus multilocularis cyclin y 0.0015 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0171 0.0669 0.1837
Brugia malayi Cyclin, N-terminal domain containing protein 0.0063 0.021 0.0576
Schistosoma mansoni tubulin subunit beta 0.0472 0.1946 0.2689
Echinococcus granulosus alpha 1A adrenergic receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Echinococcus granulosus 7TM GPCR rhodopsin 0.0645 0.2679 0.3703
Echinococcus granulosus g protein coupled receptor 0.0645 0.2679 0.3703
Echinococcus granulosus lamin dm0 0.0026 0.0053 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0051 0.0141
Echinococcus granulosus dro:myosuppressin receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Brugia malayi putative neuropeptide receptor NPR1 0.0645 0.2679 0.7358
Echinococcus granulosus neuropeptide receptor 0.1719 0.7234 1
Trypanosoma cruzi cdc2-related kinase 3 0.009 0.0322 0.1631
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni myosin xvIII 0.0645 0.2679 0.3703
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.009 0.0322 0.0886
Toxoplasma gondii exonuclease III APE 0.0037 0.0099 0.049
Echinococcus multilocularis 0.0119 0.0446 0.0617
Echinococcus multilocularis cyclin t1 0.0015 0.0006 0.0008
Trypanosoma brucei RNA helicase, putative 0.0769 0.3204 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0052 0.0072
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.004 0.0174
Brugia malayi Melatonin receptor type 1A 0.0645 0.2679 0.7358
Schistosoma mansoni hypothetical protein 0.0645 0.2679 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Plasmodium falciparum plasmepsin III 0.0059 0.0191 0.0955
Brugia malayi celfurPC protein 0.0119 0.0446 0.1226
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0052 0.0072
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0015 0.0006 0.0008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0053 0.0147
Plasmodium falciparum plasmepsin V 0.0059 0.0191 0.0955
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0052 0.0144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Loa Loa (eye worm) proprotein convertase 2 0.0035 0.0089 0.0245
Trypanosoma brucei mitotic cyclin 6 0.0126 0.0477 0.1471
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0099 0.0478
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0645 0.2679 0.3703
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0052 0.0144
Brugia malayi RE15519p 0.0645 0.2679 0.7358
Mycobacterium tuberculosis Conserved protein 0.0048 0.0145 0.0133
Trichomonas vaginalis cyclin A, putative 0.0126 0.0477 0.2425
Leishmania major beta tubulin 0.0472 0.1946 1
Schistosoma mansoni biogenic amine receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.0203 0.1016
Echinococcus multilocularis neuropeptides capa receptor 0.0645 0.2679 0.3703
Toxoplasma gondii aspartyl protease ASP3 0.0059 0.0191 0.0966
Loa Loa (eye worm) melatonin receptor type 1A 0.0645 0.2679 0.7358
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0645 0.2679 0.3703
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0062 0.0203 0.1027
Echinococcus granulosus serotonin receptor 0.0645 0.2679 0.3703
Brugia malayi neuropeptide F receptor 0.0645 0.2679 0.7358
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0145 0.0714
Loa Loa (eye worm) hypothetical protein 0.0126 0.0477 0.1309
Brugia malayi G protein-coupled receptor 0.0645 0.2679 0.7358
Loa Loa (eye worm) hypothetical protein 0.0079 0.0278 0.0764
Trichomonas vaginalis tubulin alpha chain, putative 0.0472 0.1946 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0278 0.0764
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0645 0.2679 0.3703
Toxoplasma gondii cyclin 4, putative 0.0015 0.0006 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0052 0.0072
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0052 0.0144
Loa Loa (eye worm) hypothetical protein 0.0148 0.0567 0.1558
Schistosoma mansoni hypothetical protein 0.0769 0.3204 0.4429
Echinococcus multilocularis cyclin b3 0.0063 0.021 0.029
Toxoplasma gondii aspartyl protease ASP1 0.0249 0.0999 0.5124
Brugia malayi Dopamine receptor protein 2 0.0645 0.2679 0.7358
Schistosoma mansoni hypothetical protein 0.0015 0.0006 0.0008
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0024 0.0033
Trichomonas vaginalis cyclins, putative 0.0063 0.021 0.105
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0052 0.0144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0052 0.0072
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0712 0.0984
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0012 0.0028
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0008 0.001
Echinococcus granulosus Tubulin beta 2C chain 0.0472 0.1946 0.2689
Trichomonas vaginalis cyclin B, putative 0.0126 0.0477 0.2425
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0144 0.0711
Schistosoma mansoni hypothetical protein 0.0029 0.0062 0.0086
Trichomonas vaginalis tubulin, putative 0.0472 0.1946 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Trypanosoma brucei unspecified product 0.0019 0.0024 0.0056
Plasmodium falciparum plasmepsin IX 0.0059 0.0191 0.0955
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0448 0.123
Echinococcus granulosus neuropeptide receptor A26 0.0645 0.2679 0.3703
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0048 0.0145 0.0133
Loa Loa (eye worm) hypothetical protein 0.0069 0.0235 0.0646
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0035 0.0089 0.0428
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Schistosoma mansoni thyroid hormone receptor 0.0154 0.0594 0.0821
Schistosoma mansoni coup transcription factor 0.0026 0.0052 0.0072
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0028 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0052 0.0144
Echinococcus multilocularis Tubulin beta 2C chain 0.0472 0.1946 0.2689
Plasmodium falciparum calcium-dependent protein kinase 5 0.0062 0.0203 0.1016
Echinococcus granulosus cyclins 0.0063 0.021 0.029
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0052 0.0072
Schistosoma mansoni hypothetical protein 0.0079 0.0278 0.0384
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.0669 0.1837
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0052 0.0144
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0024 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0406 0.1664 0.4571
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0024 0.0092
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0001 0.0004
Brugia malayi Serotonin receptor 0.0645 0.2679 0.7358
Echinococcus granulosus furin 0.0148 0.0567 0.0784
Echinococcus multilocularis tubulin beta 1 chain 0.0472 0.1946 0.2689
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.0235 0.1181
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni ap endonuclease 0.0037 0.0099 0.0137
Trypanosoma brucei trypanothione reductase 0.0048 0.0144 0.0431
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0645 0.2679 0.7358
Brugia malayi nuclear hormone receptor 0.0026 0.0052 0.0144
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0645 0.2679 0.3703
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0052 0.0072
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.237 1 1
Echinococcus multilocularis cyclin k 0.0015 0.0006 0.0008
Trypanosoma brucei cdc2-related kinase 1 0.009 0.0322 0.0989
Echinococcus multilocularis g protein coupled receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0195 0.0184
Entamoeba histolytica cyclin family protein 0.0063 0.021 0.105
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0235 0.0325
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0404 0.0393
Plasmodium falciparum plasmepsin II 0.0249 0.0999 0.5118
Trypanosoma cruzi CYC2-like cyclin, putative 0.0126 0.0477 0.2425
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Trichomonas vaginalis cyclin B, putative 0.0126 0.0477 0.2425
Loa Loa (eye worm) hypothetical protein 0.0249 0.0999 0.2743
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0645 0.2679 0.3703
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Brugia malayi cyclin fold protein 1 variant b 0.0015 0.0006 0.0017
Brugia malayi Dopamine receptor protein 1 0.0645 0.2679 0.7358
Loa Loa (eye worm) hypothetical protein 0.0406 0.1664 0.4571
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0144 0.0395
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0024 0.0056
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.004 0.0109
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Plasmodium falciparum plasmepsin I 0.0249 0.0999 0.5118
Schistosoma mansoni opsin-like receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0048 0.0145 0.0714
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0062 0.0203 0.1027
Brugia malayi Tubulin beta-1 chain 0.0472 0.1946 0.5344
Schistosoma mansoni lamin 0.0026 0.0053 0.0074
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Entamoeba histolytica cell division protein kinase 2, putative 0.009 0.0322 0.1631
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0059 0.0191 0.0525
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.009 0.0322 0.1631
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis neuropeptide receptor A26 0.0645 0.2679 0.3703
Plasmodium falciparum thioredoxin reductase 0.0017 0.0012 0.0028
Brugia malayi Cam kinase protein 1 0.0062 0.0203 0.0558
Onchocerca volvulus 0.0645 0.2679 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0012 0.0041
Toxoplasma gondii beta tubulin 0.0472 0.1946 1
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.009 0.0322 0.0445
Trypanosoma cruzi hypothetical protein, conserved 0.0416 0.1707 0.8771
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.1006 0.2763
Echinococcus granulosus dna polymerase kappa 0.0019 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis Furin 1 0.0035 0.0089 0.0123
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0052 0.0144
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0712 0.0984
Loa Loa (eye worm) BEN-1 protein 0.0472 0.1946 0.5344
Echinococcus multilocularis cyclin G2 0.0015 0.0006 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0382 0.0528
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0099 1
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1022 0.5237
Giardia lamblia Beta tubulin 0.0472 0.1946 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Schistosoma mansoni opsin-like receptor 0.0645 0.2679 0.3703
Schistosoma mansoni hypothetical protein 0.0079 0.0278 0.0384
Loa Loa (eye worm) neuropeptide F receptor 0.0645 0.2679 0.7358
Leishmania major beta tubulin 0.0472 0.1946 1
Echinococcus multilocularis cyclin dependent kinase 0.009 0.0322 0.0446
Brugia malayi steroid hormone receptor 0.0026 0.0052 0.0144
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0382 0.0528
Echinococcus granulosus myosin light chain kinase smooth muscle 0.0241 0.0965 0.1335
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0006 0.0017
Loa Loa (eye worm) cyclin domain-containing protein 0.0063 0.021 0.0576
Brugia malayi sulfakinin receptor protein 0.0645 0.2679 0.7358
Brugia malayi Thioredoxin reductase 0.0048 0.0144 0.0395
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0024 0.0056
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0007 0.0018
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0062 0.0203 0.0558
Echinococcus multilocularis g-protein coupled receptor 0.0645 0.2679 0.3703
Schistosoma mansoni hypothetical protein 0.0079 0.0278 0.0384
Loa Loa (eye worm) G-protein coupled receptor 0.0645 0.2679 0.7358
Echinococcus granulosus lamin 0.0026 0.0053 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Echinococcus granulosus neuropeptides capa receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0029 0.0062 0.029
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0015 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus calcium dependent protein kinase 0.0059 0.0191 0.0264
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0455 0.0054
Echinococcus multilocularis serotonin receptor 0.0645 0.2679 0.3703
Schistosoma mansoni cathepsin D (A01 family) 0.0735 0.3059 0.4229
Giardia lamblia Cyclin A 0.0063 0.021 0.105
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi Cyclin, N-terminal domain containing protein 0.0126 0.0477 0.1309
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0024 0.0013
Leishmania major hypothetical protein, conserved 0.0416 0.1707 0.8771
Giardia lamblia G2/mitotic-specific cyclin B 0.0126 0.0477 0.2425
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0195 0.0986
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0012 0.0028
Loa Loa (eye worm) glutathione reductase 0.0048 0.0144 0.0395
Echinococcus granulosus bloom syndrome protein 0.0023 0.004 0.0055
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0322 0.1628
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi hypothetical protein 0.0015 0.0006 0.0017
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus granulosus cyclin y 0.0015 0.0006 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0062 0.0203 0.0281
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Toxoplasma gondii cyclin dependent kinase binding protein 0.0015 0.0006 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Schistosoma mansoni growth hormone secretagogue receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi Pepsin A precursor 0.0059 0.0191 0.0525
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Onchocerca volvulus 0.0026 0.0052 0.0173
Echinococcus granulosus Tubulin beta 2C chain 0.0472 0.1946 0.2689
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0052 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0416 0.1707 0.8771
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0099 0.0137
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0024 0.0092
Plasmodium falciparum plasmepsin X 0.0059 0.0191 0.0955
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus multilocularis allatostatin A receptor 0.0645 0.2679 0.3703
Brugia malayi hypothetical protein 0.0059 0.0191 0.0525
Giardia lamblia DINP protein human, muc B family 0.0019 0.0024 0.0092
Plasmodium falciparum thioredoxin reductase 0.0048 0.0144 0.0711
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0052 0.0072
Echinococcus multilocularis tubulin subunit beta 0.0472 0.1946 0.2689
Echinococcus granulosus tm gpcr rhodopsin 0.0645 0.2679 0.3703
Brugia malayi Melibiase family protein 0.0069 0.0235 0.0646
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1022 0.5237
Trichomonas vaginalis cyclin D, putative 0.0063 0.021 0.105
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0099 0.0087
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0645 0.2679 1
Trypanosoma cruzi cdc2-related kinase 1 0.009 0.0322 0.1631
Echinococcus granulosus citrate lyase subunit beta protein 0.0048 0.0145 0.02
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0712 0.0984
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0144 0.0199
Schistosoma mansoni alpha-1 adrenergic receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis neuropeptide s receptor 0.0645 0.2679 0.3703
Echinococcus granulosus neuroendocrine convertase 2 0.0093 0.0335 0.0463
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0404 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Echinococcus granulosus allatostatin A receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Loa Loa (eye worm) hypothetical protein 0.0058 0.0187 0.0513
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0016
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.009 0.0322 0.0886
Echinococcus granulosus sex peptide receptor 0.0645 0.2679 0.3703
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.009 0.0322 0.0446
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Plasmodium falciparum glutathione reductase 0.0048 0.0144 0.0711
Leishmania major beta tubulin 0.0472 0.1946 1
Trichomonas vaginalis cyclins, putative 0.0126 0.0477 0.2425
Echinococcus granulosus cyclin t1 0.0015 0.0006 0.0008
Trypanosoma cruzi cdc2-related kinase 3 0.009 0.0322 0.1631
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0052 0.0072
Brugia malayi G-protein coupled receptor 0.0645 0.2679 0.7358
Trichomonas vaginalis cyclins, putative 0.0126 0.0477 0.2425
Leishmania major DNA polymerase eta, putative 0.0019 0.0024 0.0092
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0249 0.0999 0.1381
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni amine GPCR 0.0645 0.2679 0.3703
Onchocerca volvulus 0.0645 0.2679 1
Schistosoma mansoni amine GPCR 0.0645 0.2679 0.3703
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0035 0.0089 0.0428
Plasmodium vivax plasmepsin V, putative 0.0059 0.0191 0.0955
Echinococcus multilocularis serine:threonine protein kinase 0.0241 0.0965 0.1335
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0235 0.0325
Echinococcus multilocularis neuropeptide receptor 0.1719 0.7234 1
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0203 0.0281
Loa Loa (eye worm) hypothetical protein 0.0087 0.031 0.0852
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Toxoplasma gondii thioredoxin reductase 0.0048 0.0144 0.0723
Echinococcus granulosus GPCR family 2 0.0079 0.0278 0.0384
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0052 0.0144
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0712 0.0984
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0645 0.2679 0.3703
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0006 0.0017
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0104 0.0382 0.0528
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0099 0.0478
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0029 0.0062 0.029
Trichomonas vaginalis tubulin gamma chain, putative 0.0472 0.1946 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0052 0.0144
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1022 0.5237
Plasmodium falciparum calcium-dependent protein kinase 4 0.0062 0.0203 0.1016
Echinococcus granulosus fmrfamide receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0035 0.0089 0.0428
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0024 0.0013
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0017
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0062 0.0203 0.1016
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0433 0.1779 0.4887
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Trichomonas vaginalis cyclins, putative 0.0078 0.0273 0.1375
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0278 0.0384
Mycobacterium ulcerans hypothetical protein 0.0048 0.0145 0.0133
Schistosoma mansoni Cyclin fold protein 0.0015 0.0006 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1022 0.5237
Leishmania major beta tubulin 0.0472 0.1946 1
Trypanosoma cruzi cyclin, putative 0.0126 0.0477 0.2425
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0645 0.2679 0.7358
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0793 0.3308 0.4572
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0099 0.0478
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0012 0.5
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0052 0.0072
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0035 0.0089 0.0123
Brugia malayi Protein kinase domain containing protein 0.009 0.0322 0.0886
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Echinococcus granulosus cyclin 0.0015 0.0006 0.0008
Echinococcus granulosus beta tubulin 0.0472 0.1946 0.2689
Giardia lamblia Kinase, CMGC CDK 0.009 0.0322 0.1631
Trypanosoma brucei cdc2-related kinase 3 0.009 0.0322 0.0989
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus cyclin B3 1 0.0063 0.021 0.029
Trypanosoma cruzi cdc2-related kinase 1 0.009 0.0322 0.1631
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0712 0.0984
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0017
Echinococcus multilocularis cyclin dependent kinase 1 0.009 0.0322 0.0446
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0024 0.0056
Loa Loa (eye worm) G-protein coupled receptor 0.0645 0.2679 0.7358
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0688 0.3518
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0015 0.0006 0.0013
Echinococcus granulosus Cyclin L1 0.0015 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0062 0.0203 0.0558
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0278 0.0384
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Echinococcus multilocularis bloom syndrome protein 0.0023 0.004 0.0055
Brugia malayi neuropeptide F receptor 0.0645 0.2679 0.7358
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0249 0.0999 0.5124
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0012 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Plasmodium vivax aspartyl protease, putative 0.0059 0.0191 0.0955
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0048 0.0145 0.0133
Toxoplasma gondii hypothetical protein 0.0048 0.0145 0.0728
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0052 0.0072
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0195 0.0184
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Brugia malayi ecdysteroid receptor 0.0026 0.0052 0.0144
Echinococcus multilocularis neuropeptide Y receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Schistosoma mansoni lamin 0.0026 0.0053 0.0074
Entamoeba histolytica tubulin family protein 0.0472 0.1946 1
Echinococcus granulosus cyclins 0.0063 0.021 0.029
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0035 0.0089 0.0428
Echinococcus granulosus cyclin dependent kinase 5 0.009 0.0322 0.0446
Loa Loa (eye worm) hypothetical protein 0.0063 0.0208 0.0571
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0052 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Echinococcus multilocularis neuropeptide FF receptor 2 0.0645 0.2679 0.3703
Plasmodium vivax glutathione reductase, putative 0.0048 0.0144 0.0711
Loa Loa (eye worm) hypothetical protein 0.0059 0.0191 0.0525
Brugia malayi endoprotease bli-4 precursor 0.0148 0.0567 0.1558
Brugia malayi MH2 domain containing protein 0.0119 0.0448 0.123
Brugia malayi neuroendocrine convertase 1 precursor 0.0093 0.0335 0.0919
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.0688 0.3518
Entamoeba histolytica protein kinase, putative 0.0062 0.0203 0.1016
Plasmodium falciparum plasmepsin VI 0.0249 0.0999 0.5118
Loa Loa (eye worm) hypothetical protein 0.0026 0.0053 0.0147
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0063 0.021 0.029
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0645 0.2679 0.3703
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0052 0.0072
Brugia malayi aspartic protease BmAsp-1, identical 0.0059 0.0191 0.0525
Echinococcus granulosus neuropeptide s receptor 0.0645 0.2679 0.3703
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0099 0.0137
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0404 0.0393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Schistosoma mansoni neuropeptide receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0117 0.0437 0.1201
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0322 0.0446
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0006 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.009 0.0322 0.1631
Loa Loa (eye worm) tubulin beta-1 chain 0.0472 0.1946 0.5344
Echinococcus multilocularis g protein coupled receptor 0.0645 0.2679 0.3703
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0404 0.0393
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0099 0.0478
Trichomonas vaginalis cyclin B3, putative 0.0063 0.021 0.105
Echinococcus multilocularis cyclin dependent kinase 1 0.009 0.0322 0.0446
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0024 0.0066
Brugia malayi glutathione reductase 0.0048 0.0144 0.0395
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0052 0.0144
Echinococcus granulosus tachykinin peptides receptor 99D 0.0645 0.2679 0.3703
Trypanosoma brucei beta tubulin 0.0472 0.1946 0.6065
Schistosoma mansoni cyclin d 0.0015 0.0006 0.0008
Echinococcus granulosus orexin receptor type 2 0.0645 0.2679 0.3703
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0455 0.0444
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0052 0.0144
Echinococcus granulosus Tubulin beta 2C chain 0.0472 0.1946 0.2689
Echinococcus multilocularis GPCR, family 2 0.0079 0.0278 0.0384
Echinococcus granulosus neuropeptide FF receptor 2 0.0645 0.2679 0.3703
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0052 0.0072
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0455 0.0444
Schistosoma mansoni tubulin subunit beta 0.0472 0.1946 0.2689
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0048 0.0145 0.0133
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0645 0.2679 0.3703
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0062 0.0203 0.0281
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0052 0.0144
Plasmodium falciparum tubulin beta chain 0.0472 0.1946 1
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0015 0.0006 0.0008
Leishmania major beta tubulin 0.0472 0.1946 1
Onchocerca volvulus 0.0645 0.2679 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni amine GPCR 0.0645 0.2679 0.3703
Schistosoma mansoni neuropeptide F-like receptor 0.0645 0.2679 0.3703
Trypanosoma brucei hypothetical protein, conserved 0.0416 0.1707 0.532
Leishmania major beta tubulin 0.0472 0.1946 1
Echinococcus multilocularis fmrfamide receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) tubulin beta-4 chain 0.0472 0.1946 0.5344
Trichomonas vaginalis cyclin B, putative 0.0126 0.0477 0.2425
Schistosoma mansoni g1/s-specific cyclin C 0.0015 0.0006 0.0008
Loa Loa (eye worm) CYL-1 protein 0.0015 0.0006 0.0017
Mycobacterium tuberculosis Probable reductase 0.0109 0.0404 0.0393
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0099 0.0271
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0645 0.2679 0.7358
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0249 0.0999 0.5118
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0645 0.2679 0.3703
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis hypothetical protein 0.0029 0.0062 0.029
Echinococcus multilocularis cyclin A3 4 0.0015 0.0006 0.0008
Echinococcus granulosus g protein coupled receptor 0.0645 0.2679 0.3703
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Echinococcus granulosus g-protein coupled receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0024 0.0092
Loa Loa (eye worm) BEN-1 protein 0.0472 0.1946 0.5344
Schistosoma mansoni hypothetical protein 0.0171 0.0669 0.0925
Echinococcus granulosus Tubulin beta 2C chain 0.0472 0.1946 0.2689
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0062 0.0203 0.1027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Echinococcus multilocularis cyclin y 0.0015 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis neuropeptides capa receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) RecQ helicase 0.0023 0.004 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0062 0.029
Trichomonas vaginalis glucosylceramidase, putative 0.0167 0.065 0.3321
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0126 0.0477 0.2425
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0052 0.0072
Echinococcus multilocularis cyclin 0.0015 0.0006 0.0008
Toxoplasma gondii hypothetical protein 0.0015 0.0006 0.0013
Onchocerca volvulus 0.0645 0.2679 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.0062 0.0203 0.1016
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Echinococcus granulosus g protein coupled receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0052 0.0144
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0645 0.2679 0.7358
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0012 0.0028
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0052 0.0072
Brugia malayi beta-tubulin, identical 0.0472 0.1946 0.5344
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.0052 0.0173
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0645 0.2679 0.7358
Echinococcus granulosus cyclin B 0.0126 0.0477 0.0659
Entamoeba histolytica tubulin family protein 0.0472 0.1946 1
Echinococcus granulosus cyclin y 0.0015 0.0006 0.0008
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0404 0.0393
Brugia malayi aspartic protease BmAsp-2, identical 0.0059 0.0191 0.0525
Trypanosoma cruzi cyclin, putative 0.0126 0.0477 0.2425
Onchocerca volvulus 0.0645 0.2679 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0195 0.0184
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.1022 0.2806
Plasmodium falciparum glutathione reductase 0.0017 0.0012 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Echinococcus multilocularis myosin light chain kinase, smooth muscle 0.0241 0.0965 0.1335
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0052 0.0072
Echinococcus granulosus cyclins 0.0063 0.021 0.029
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0015 0.0006 0.0013
Schistosoma mansoni neuropeptide receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis Tubulin beta 2C chain 0.0472 0.1946 0.2689
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0052 0.0072
Echinococcus multilocularis somatostatin receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0059 0.0191 0.0525
Echinococcus multilocularis cyclin dependent kinase 5 0.009 0.0322 0.0446
Schistosoma mansoni hypothetical protein 0.0079 0.0278 0.0384
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Echinococcus multilocularis cyclin B3 1 0.0063 0.021 0.029
Echinococcus multilocularis Cyclin L1 0.0015 0.0006 0.0008
Echinococcus multilocularis cyclin B 0.0126 0.0477 0.0659
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0645 0.2679 0.3703
Loa Loa (eye worm) cyclin domain-containing protein 0.0015 0.0006 0.0017
Brugia malayi hypothetical protein 0.0015 0.0006 0.0017
Trypanosoma cruzi cyclin 6, putative 0.0126 0.0477 0.2425
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0099 0.0478
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0012 0.0028
Brugia malayi Cyclin, N-terminal domain containing protein 0.0015 0.0006 0.0017
Echinococcus multilocularis dna polymerase eta 0.0019 0.0024 0.0033
Leishmania major beta tubulin 0.0472 0.1946 1
Schistosoma mansoni protein kinase 0.0495 0.2041 0.2821
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0092
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis G1:S specific cyclin D1 0.0015 0.0006 0.0008
Leishmania major trypanothione reductase 0.0048 0.0144 0.0711
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0249 0.0999 0.1381
Onchocerca volvulus 0.0645 0.2679 1
Brugia malayi nuclear receptor NHR-88 0.0026 0.0052 0.0144
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi AKH receptor 0.0645 0.2679 0.7358
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0645 0.2679 0.3703
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0012 0.0028
Echinococcus multilocularis serotonin receptor 0.0645 0.2679 0.3703
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0645 0.2679 0.7358
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0053 0.0147
Leishmania major cyclin 0.0126 0.0477 0.2425
Loa Loa (eye worm) beta-tubulin 0.0472 0.1946 0.5344
Echinococcus granulosus rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Brugia malayi Cyclin C 0.0015 0.0006 0.0017
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0144
Echinococcus granulosus tubulin beta 4A class IVa 0.0472 0.1946 0.2689
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0433 0.1779 0.4887
Echinococcus granulosus cyclins 0.0063 0.021 0.029
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0872 0.3641 1
Giardia lamblia High cysteine membrane protein Group 2 0.0055 0.0174 0.0865
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Echinococcus multilocularis neuroendocrine convertase 2 0.0093 0.0335 0.0463
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0052 0.0144
Echinococcus granulosus beta tubulin 0.0472 0.1946 0.2689
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0278 0.0764
Plasmodium vivax tubulin beta chain, putative 0.0472 0.1946 1
Trypanosoma brucei beta tubulin 0.0472 0.1946 0.6065
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0645 0.2679 0.3703
Onchocerca volvulus 0.0645 0.2679 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0052 0.0072
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0645 0.2679 0.3703
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0234 0.0936 0.1294
Leishmania major beta tubulin 0.0472 0.1946 1
Echinococcus granulosus cyclin dependent kinase 0.009 0.0322 0.0446
Brugia malayi GnHR receptor homolog 0.0645 0.2679 0.7358
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Echinococcus multilocularis beta tubulin 0.0472 0.1946 0.2689
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0144 0.0711
Schistosoma mansoni ap endonuclease 0.0037 0.0099 0.0137
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0382 0.0528
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni tubulin subunit beta 0.0472 0.1946 0.2689
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0052 0.0144
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0062 0.0203 0.0558
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Schistosoma mansoni biogenic amine (5HT) receptor 0.0645 0.2679 0.3703
Schistosoma mansoni tubulin subunit beta 0.0472 0.1946 0.2689
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0195 0.027
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0062 0.0203 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0322 0.0446
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0448 0.123
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0048 0.0145 0.0714
Entamoeba histolytica cyclin, putative 0.0126 0.0477 0.2425
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0645 0.2679 0.3703
Schistosoma mansoni cathepsin D (A01 family) 0.0735 0.3059 0.4229
Schistosoma mansoni DNA polymerase eta 0.0019 0.0024 0.0033
Onchocerca volvulus 0.0645 0.2679 1
Echinococcus multilocularis fmrfamide receptor 0.0645 0.2679 0.3703
Leishmania major protein kinase, putative 0.0062 0.0203 0.1016
Schistosoma mansoni intermediate filament proteins 0.0026 0.0053 0.0074
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0012 0.0032
Plasmodium vivax plasmepsin IV, putative 0.0249 0.0999 0.5118
Toxoplasma gondii melibiase subfamily protein 0.0104 0.0382 0.1948
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0015 0.0006 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0052 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0066
Echinococcus multilocularis dro:myosuppressin receptor 0.0645 0.2679 0.3703
Echinococcus granulosus intermediate filament protein 0.0026 0.0053 0.0074
Toxoplasma gondii beta-1 tubulin, putative 0.0472 0.1946 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Entamoeba histolytica cell division protein kinase 2, putative 0.009 0.0322 0.1631
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.021 0.105
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0099 1
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0015 0.0006 0.0008
Echinococcus multilocularis thyroid hormone receptor alpha 0.0154 0.0594 0.0821
Schistosoma mansoni cyclin G 0.0015 0.0006 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Echinococcus granulosus dna polymerase eta 0.0019 0.0024 0.0033
Trichomonas vaginalis tubulin beta chain, putative 0.0472 0.1946 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0024 0.0056
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Giardia lamblia Furin precursor putative serine protease 0.0029 0.0062 0.029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0035 0.0089 0.0428
Schistosoma mansoni biogenic amine receptor 0.0645 0.2679 0.3703
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0195 0.027
Echinococcus multilocularis Tubulin beta 2C chain 0.0472 0.1946 0.2689
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0062 0.0203 0.0281
Onchocerca volvulus 0.0026 0.0053 0.0177
Plasmodium falciparum calcium-dependent protein kinase 3 0.0062 0.0203 0.1016
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0052 0.0144
Schistosoma mansoni histamine h1 receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0052 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0052 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0195 0.027
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi Serotonin receptor 0.0645 0.2679 0.7358
Echinococcus granulosus cyclin A3 4 0.0015 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0483 0.0667
Leishmania major beta tubulin 0.0472 0.1946 1
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0024 0.0033
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0024 0.0066
Trypanosoma cruzi beta tubulin, putative 0.0472 0.1946 1
Onchocerca volvulus 0.0059 0.0191 0.0693
Trichomonas vaginalis tubulin epsilon chain, putative 0.0472 0.1946 1
Echinococcus granulosus Furin 1 0.0035 0.0089 0.0123
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0645 0.2679 0.3703
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0024 0.0013
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0645 0.2679 0.3703
Onchocerca volvulus 0.0126 0.0477 0.176
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0015 0.0006 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0645 0.2679 0.3703
Echinococcus granulosus serine:threonine protein kinase 0.0241 0.0965 0.1335
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1022 0.5237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0052 0.0144
Echinococcus granulosus Tubulin beta 2C chain 0.0472 0.1946 0.2689
Plasmodium vivax calcium-dependent protein kinase, putative 0.0062 0.0203 0.1016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0024 0.0092
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0017
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0144 0.0199
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0012 0.0017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0035 0.0089 0.0428
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0495 0.2041 0.2821
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0645 0.2679 0.3703
Echinococcus granulosus cyclin k 0.0015 0.0006 0.0008
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0052 0.0144
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0012 0.0028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.009 0.0322 0.1628
Entamoeba histolytica protein kinase, putative 0.0062 0.0203 0.1016
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.009 0.0322 0.0445
Echinococcus granulosus neuropeptides capa receptor 0.0645 0.2679 0.3703
Echinococcus granulosus tm gpcr rhodopsin 0.0645 0.2679 0.3703
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Schistosoma mansoni memapsin-2 (A01 family) 0.0059 0.0191 0.0264
Echinococcus multilocularis G protein coupled receptor 139 0.1719 0.7234 1
Echinococcus multilocularis orexin receptor type 2 0.0645 0.2679 0.3703
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0712 0.0984
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0063 0.021 0.029
Echinococcus multilocularis beta tubulin 0.0472 0.1946 0.2689
Brugia malayi hypothetical protein 0.0645 0.2679 0.7358
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.1006 0.2763
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0029 0.0062 0.029
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0099 0.0478
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0053 0.0147
Echinococcus multilocularis calcium dependent protein kinase 0.0059 0.0191 0.0264
Loa Loa (eye worm) tubulin beta-2A chain 0.0472 0.1946 0.5344
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0099 0.0478
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0062 0.0203 0.0281
Leishmania major beta tubulin 0.0472 0.1946 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0195 0.0184
Trichomonas vaginalis cyclin B, putative 0.0063 0.021 0.105
Echinococcus granulosus cyclin b3 0.0063 0.021 0.029
Trypanosoma brucei beta tubulin 0.0472 0.1946 0.6065
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0062 0.0203 0.0616
Mycobacterium ulcerans hypothetical protein 0.0048 0.0145 0.0133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0645 0.2679 0.3703
Brugia malayi larval opioid receptor 0.0645 0.2679 0.7358
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0099 0.0087
Trichomonas vaginalis cyclin D, putative 0.0063 0.021 0.105
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0645 0.2679 0.3703
Entamoeba histolytica cyclin family protein 0.0063 0.021 0.105
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0012 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.1022 0.5237
Trichomonas vaginalis cyclins, putative 0.0126 0.0477 0.2425
Loa Loa (eye worm) hypothetical protein 0.0645 0.2679 0.7358
Echinococcus granulosus hypothetical protein 0.0645 0.2679 0.3703
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0024 0.0092
Echinococcus multilocularis cyclins 0.0063 0.021 0.029
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.1022 0.2806
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0645 0.2679 0.3703
Loa Loa (eye worm) cyclin C 0.0015 0.0006 0.0017
Echinococcus granulosus biogenic amine 5HT receptor 0.0645 0.2679 0.3703
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0052 0.0072
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.004 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0645 0.2679 0.3703
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0059 0.0191 0.0264
Echinococcus granulosus 7tm_1 domain containing protein 0.0645 0.2679 0.3703
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0052 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0024 0.0056
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0195 0.0975
Leishmania major beta tubulin 0.0472 0.1946 1
Schistosoma mansoni protein kinase 0.0495 0.2041 0.2821
Schistosoma mansoni neuropeptide f receptor 76f 0.0645 0.2679 0.3703
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0382 0.0528

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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