Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0234 | 0.033 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0138 | 0.0127 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0113 | 0.0113 |
Onchocerca volvulus | 0.0024 | 0.0091 | 0.0371 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0091 | 0.008 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0152 | 0.0152 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0264 | 0.0253 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0091 | 0.008 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.0091 | 0.5697 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0212 | 0.0212 |
Echinococcus granulosus | dihydrofolate reductase | 0.2164 | 1 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.1463 | 0.6754 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0415 | 0.19 | 0.1891 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0041 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0018 | 0.0018 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0018 | 0.0018 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.2164 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0091 | 0.008 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0152 | 0.0208 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0011 | 0.0005 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0011 | 0.0026 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0052 | 0.0041 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0091 | 0.008 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0052 | 0.0041 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0018 | 0.0018 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0091 | 0.008 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0113 | 0.0113 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0053 | 0.0061 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0061 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0018 | 0.0006 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0058 | 0.0051 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0018 | 0.0006 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0091 | 0.0085 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0152 | 0.1417 |
Onchocerca volvulus | 0.0029 | 0.0113 | 0.0473 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0052 | 0.0052 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0041 |
Brugia malayi | MH2 domain containing protein | 0.0125 | 0.0556 | 0.0556 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0224 | 0.1018 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0091 | 0.008 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0091 | 0.5697 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0091 | 0.008 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0018 | 0.0006 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0018 | 0.0006 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0152 | 0.0208 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0152 | 0.0152 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0011 | 0.0011 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0152 | 0.0208 |
Schistosoma mansoni | dihydrofolate reductase | 0.2164 | 1 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0472 | 0.2164 | 0.2155 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0152 | 0.014 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.2164 | 1 | 1 |
Echinococcus multilocularis | smad | 0.0009 | 0.0018 | 0.0006 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0053 | 0.0061 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0091 | 0.008 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0152 | 0.0208 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0052 | 0.0041 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0011 | 0.0005 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0041 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0138 | 0.0138 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0212 | 0.0212 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0053 | 0.0061 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1463 | 0.6754 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0091 | 0.0119 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.0011 | 0.0011 |
Echinococcus granulosus | microtubule associated protein 2 | 0.07 | 0.322 | 0.3212 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0091 | 0.0091 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0091 | 0.008 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | thymidylate synthase | 0.0472 | 0.2164 | 0.2164 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0472 | 0.2164 | 0.2158 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0152 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0018 | 0.0018 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0052 | 0.0052 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0063 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0052 | 0.0052 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0091 | 0.0119 |
Brugia malayi | thymidylate synthase | 0.0472 | 0.2164 | 0.2164 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0018 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0041 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.1463 | 0.6754 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0011 | 0.0026 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0134 | 0.0127 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0152 | 0.1417 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.0774 | 0.0764 |
Chlamydia trachomatis | dihydrofolate reductase | 0.2164 | 1 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0121 | 0.011 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.0011 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0091 | 0.0091 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0121 | 0.011 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.0011 | 0.0005 |
Echinococcus granulosus | thymidylate synthase | 0.0472 | 0.2164 | 0.2155 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0011 | 0.0011 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0091 | 0.0091 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0058 | 0.0051 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0018 | 0.0006 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0224 | 0.1018 | 0.1012 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0063 | 0.0051 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0053 | 0.0061 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0058 | 0.0051 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.002 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0011 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0041 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0052 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0041 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0121 | 0.011 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0152 | 0.014 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0152 | 0.014 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.0011 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.0774 | 0.0764 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0041 |
Echinococcus granulosus | dnaJ subfamily B | 0.0415 | 0.19 | 0.1891 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.002 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0063 | 0.0063 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0053 | 0.0041 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0011 | 0.0011 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0472 | 0.2164 | 0.2155 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0052 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0041 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0011 | 0.0005 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0212 | 0.0212 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0063 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0063 | 0.0063 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0061 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.2164 | 1 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0052 | 0.0041 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0058 | 0.0051 |
Echinococcus granulosus | geminin | 0.0172 | 0.0774 | 0.0764 |
Schistosoma mansoni | microtubule-associated protein tau | 0.07 | 0.322 | 0.3212 |
Onchocerca volvulus | 0.0472 | 0.2164 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0011 | 0.0011 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0019 | 0.0019 |
Echinococcus multilocularis | thymidylate synthase | 0.0472 | 0.2164 | 0.2155 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.1463 | 0.6754 | 1 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0472 | 0.2164 | 0.2155 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0113 | 0.0102 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0011 | 0.0011 |
Brugia malayi | Smad1 | 0.0009 | 0.0018 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0063 | 0.0063 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.0011 | 0.0005 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0053 | 0.0046 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.1463 | 0.6754 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0152 | 0.0208 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0011 | 0.0005 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0152 | 1 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.0011 | 0.0011 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0053 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0121 | 0.011 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.0091 | 0.5697 |
Brugia malayi | Dihydrofolate reductase | 0.2164 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0063 | 0.0063 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0091 | 0.0091 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0091 | 0.0091 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0018 | 0.0006 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0011 | 0.0011 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.0011 | 0.0011 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0053 | 0.0061 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0018 | 0.0006 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0224 | 0.1018 | 0.1493 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0063 | 0.0056 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0018 | 0.0006 |
Brugia malayi | hypothetical protein | 0.0224 | 0.1018 | 0.1018 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0041 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.1463 | 0.6754 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0125 | 0.0556 | 0.0556 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0011 | 0.0011 |
Echinococcus multilocularis | dihydrofolate reductase | 0.2164 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.07 | 0.322 | 0.3212 |
Echinococcus multilocularis | geminin | 0.0172 | 0.0774 | 0.0764 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0091 | 0.0091 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0091 | 0.0085 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0152 | 0.014 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.0091 | 0.0119 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0152 | 0.1417 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0041 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0053 | 0.0061 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0053 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0052 | 0.0041 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0053 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0415 | 0.19 | 0.1891 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0125 | 0.0556 | 0.0556 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0011 | 0.0005 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.0011 | 0.0005 |
Echinococcus granulosus | smad | 0.0009 | 0.0018 | 0.0006 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0823 | 0.3788 | 0.3781 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0018 | 0.0006 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.0011 | 0.0005 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0152 | 0.014 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0091 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0063 | 0.0063 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.2164 | 1 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.002 | 0.002 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0134 | 0.0122 |
Schistosoma mansoni | smad | 0.0009 | 0.0018 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0138 | 0.0138 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0018 | 0.0006 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0018 | 0.0006 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.