Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0029 | 0.4732 | 1 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 1 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0816 | 0.0816 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Onchocerca volvulus | 0.0029 | 0.4732 | 1 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0029 | 0.4732 | 0.4732 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0816 | 0.0816 |
Schistosoma mansoni | lamin | 0.0029 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.4593 | 0.4593 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.4732 | 0.4732 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0029 | 0.4732 | 0.4732 |
Echinococcus multilocularis | lamin | 0.0029 | 0.4732 | 0.4732 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.4732 | 0.4732 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.4732 | 0.4732 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.4732 | 0.4732 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.4732 | 0.4732 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.1218 | 0.1218 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.4732 | 0.4732 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.4732 | 0.4732 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.4732 | 0.4732 |
Echinococcus granulosus | lamin | 0.0029 | 0.4732 | 0.4732 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0678 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0816 | 0.0816 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.