Detailed information for compound 654160

Basic information

Technical information
  • TDR Targets ID: 654160
  • Name: ethyl 2,5-dimethyl-1-[[4-[(4-propan-2-ylpheny l)carbamoyl]cyclohexyl]methyl]pyrrole-3-carbo xylate
  • MW: 424.576 | Formula: C26H36N2O3
  • H donors: 1 H acceptors: 2 LogP: 5.04 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1cc(n(c1C)CC1CCC(CC1)C(=O)Nc1ccc(cc1)C(C)C)C
  • InChi: 1S/C26H36N2O3/c1-6-31-26(30)24-15-18(4)28(19(24)5)16-20-7-9-22(10-8-20)25(29)27-23-13-11-21(12-14-23)17(2)3/h11-15,17,20,22H,6-10,16H2,1-5H3,(H,27,29)
  • InChiKey: HCGQBCBPDPTNSG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • ethyl 1-[[4-[(4-isopropylphenyl)carbamoyl]cyclohexyl]methyl]-2,5-dimethyl-pyrrole-3-carboxylate
  • 1-[[4-[[(4-isopropylphenyl)amino]-oxomethyl]cyclohexyl]methyl]-2,5-dimethyl-3-pyrrolecarboxylic acid ethyl ester
  • 1-[[4-[(4-isopropylphenyl)carbamoyl]cyclohexyl]methyl]-2,5-dimethyl-pyrrole-3-carboxylic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus segment polarity protein dishevelled 0.0012 0.0029 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.0303
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Echinococcus multilocularis lamin dm0 0.0026 0.0214 0.0214
Echinococcus multilocularis thioredoxin glutathione reductase 0.0098 0.1132 0.1132
Echinococcus multilocularis orexin receptor type 2 0.0088 0.1002 0.1002
Leishmania major hypothetical protein, conserved 0.0011 0.0024 0.0023
Echinococcus granulosus g protein coupled receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Brugia malayi Isocitrate dehydrogenase 0.0069 0.0763 0.0769
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0012 0.0034 0.0034
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0076 0.0853 0.088
Entamoeba histolytica serine/threonine protein kinase, putative 0.0765 0.9688 1
Loa Loa (eye worm) carbonic anhydrase 3 0.0108 0.1267 0.1302
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0022 0.0158 0.0144
Trypanosoma brucei cAMP binding protein, putative 0.0011 0.0024 0.0023
Loa Loa (eye worm) acetylcholinesterase 1 0.0495 0.6231 0.6429
Onchocerca volvulus 0.0043 0.0433 0.0423
Loa Loa (eye worm) GABA receptor subunit 0.0029 0.0253 0.0255
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0029 0.0253 0.0261
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0088 0.1002 0.1034
Plasmodium falciparum carbonic anhydrase 0.004 0.0393 0.1765
Echinococcus granulosus RUN 0.0039 0.0371 0.0383
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.004 0.0393 0.0399
Entamoeba histolytica alcohol dehydrogenase, putative 0.0022 0.016 0.0165
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.014 0.0138
Mycobacterium ulcerans transcriptional regulatory protein 0.0011 0.0024 0.0029
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0307 0.3821 0.3932
Loa Loa (eye worm) carboxylesterase 0.0495 0.6231 0.6429
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0433 0.0447
Brugia malayi Melatonin receptor type 1A 0.0088 0.1002 0.1016
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0312 0.0303
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0035 0.0322 0.0313
Schistosoma mansoni tar DNA-binding protein 0.0028 0.024 0.0248
Loa Loa (eye worm) hypothetical protein 0.0026 0.0214 0.0214
Echinococcus granulosus hypothetical protein 0.0076 0.0853 0.088
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Loa Loa (eye worm) TAR-binding protein 0.0028 0.024 0.0241
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.004 0.0385 0.0397
Loa Loa (eye worm) hypothetical protein 0.004 0.0393 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0019 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0312 0.0303
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0012 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Onchocerca volvulus 0.0088 0.1002 0.1012
Loa Loa (eye worm) transcription factor SMAD2 0.0168 0.2029 0.2089
Trypanosoma cruzi cAMP response protein 1 0.0011 0.0024 0.0005
Echinococcus granulosus arachidonate 5 lipoxygenase 0.023 0.2834 0.2925
Echinococcus granulosus lysine specific demethylase 5A 0.0026 0.0212 0.0219
Echinococcus multilocularis importin subunit beta 1 0.0035 0.032 0.032
Echinococcus granulosus dro:myosuppressin receptor 0.0088 0.1002 0.1034
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0011 0.0019 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.004 0.0393 0.0387
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.0303
Echinococcus granulosus histone acetyltransferase MYST2 0.003 0.0265 0.0273
Brugia malayi hypothetical protein 0.0025 0.0199 0.0186
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.0441
Mycobacterium ulcerans hypothetical protein 0.0011 0.0024 0.0029
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0312 0.032
Echinococcus multilocularis g protein coupled receptor 0.0088 0.1002 0.1002
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.1106 0.1142
Brugia malayi putative neuropeptide receptor 0.0088 0.1002 0.1016
Brugia malayi hypothetical protein 0.008 0.0902 0.0913
Schistosoma mansoni loxhd1 0.0039 0.0371 0.0383
Onchocerca volvulus 0.0076 0.0853 0.0857
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Mycobacterium leprae Probable polyketide synthase Pks1 0.0023 0.0176 0.0568
Trypanosoma brucei Metacaspase-4 0.0011 0.0019 0.0018
Schistosoma mansoni neuropeptide receptor 0.0369 0.4605 0.4754
Brugia malayi Dopamine receptor protein 1 0.0088 0.1002 0.1016
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0022 0.016 0.0158
Onchocerca volvulus 0.0043 0.0433 0.0423
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.032
Schistosoma mansoni jumonji domain containing protein 0.0025 0.0192 0.0198
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0012 0.0034 0.0154
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis caspase 0.0011 0.0019 0.0019
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0054 0.0575 0.0588
Leishmania major hypothetical protein, conserved 0.007 0.078 0.0803
Echinococcus granulosus peptide allatostatin:somatostatin 0.0088 0.1002 0.1034
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0057 0.0614 0.0634
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0134 0.0138
Trichomonas vaginalis spcc417.12 protein, putative 0.0084 0.0951 0.0981
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0014 0.0056 0.0056
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0011 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0088 0.1002 0.1002
Echinococcus multilocularis GPCR, family 2 0.0171 0.2068 0.2068
Schistosoma mansoni sex comb on midleg homolog 0.0027 0.0217 0.0224
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0253 0.0242
Echinococcus granulosus intermediate filament protein 0.0026 0.0214 0.0221
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0084 0.0951 0.0951
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Entamoeba histolytica hypothetical protein 0.007 0.0777 0.0802
Leishmania major metacaspase, putative 0.0011 0.0019 0.0018
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0223 0.274 0.485
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.0428
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0405 0.0411
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0022 0.016 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0011 0.0024 0.0039
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0237 0.0244
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Echinococcus granulosus importin subunit beta 1 0.0035 0.032 0.0331
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0171 0.2068 0.2068
Onchocerca volvulus 0.0088 0.1002 0.1012
Schistosoma mansoni cpg binding protein 0.003 0.0258 0.0266
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0056 0.0058
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0042 0.041 0.0404
Brugia malayi hypothetical protein 0.0025 0.0199 0.0186
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.005 0.0513 0.053
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.078 0.1378
Schistosoma mansoni carbonic anhydrase 0.004 0.0393 0.0406
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0011 0.0024 0.0025
Schistosoma mansoni neuropeptide F-like receptor 0.0088 0.1002 0.1034
Toxoplasma gondii hypothetical protein 0.004 0.0393 0.1765
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0088 0.1002 0.1034
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0069 0.0763 0.3426
Leishmania major GTP-binding protein, putative 0.0012 0.0034 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Schistosoma mansoni z-protein (S1r protein) 0.0012 0.0029 0.003
Onchocerca volvulus Putative nachr subunit 0.0054 0.0575 0.057
Schistosoma mansoni 60S ribosomal protein L21 0.0013 0.0043 0.0044
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0054 0.0575 0.0575
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0021 0.015 0.0261
Echinococcus multilocularis g-protein coupled receptor 0.0088 0.1002 0.1002
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0011 0.0024 0.0005
Schistosoma mansoni amine GPCR 0.0088 0.1002 0.1034
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0011 0.0024 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.078 0.0805
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0134 0.0134
Echinococcus granulosus cGMP dependent protein kinase 1 0.0014 0.0056 0.0058
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0088 0.1002 0.1034
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0012 0.0029 0.001
Loa Loa (eye worm) ACC-1 protein 0.0054 0.0575 0.0588
Trypanosoma brucei metacaspase 5, putative 0.0011 0.0019 0.0018
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0027 0.0217 0.0224
Trypanosoma brucei metacaspase 0.0011 0.0019 0.0018
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0494 0.051
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0433 0.0447
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0237 0.0244
Echinococcus multilocularis regulator of G protein signaling 7 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0024 0.0024
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0011 0.0024 0.011
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0134 0.0138
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0371 0.0383
Brugia malayi Dopamine receptor protein 2 0.0088 0.1002 0.1016
Brugia malayi excitatory GABA receptor EXP-1A 0.0054 0.0575 0.0575
Loa Loa (eye worm) fatty acid synthase 0.0022 0.0155 0.0153
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0108 0.1267 0.129
Toxoplasma gondii isocitrate dehydrogenase 0.0069 0.0763 0.3426
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Loa Loa (eye worm) oxidoreductase 0.0076 0.0853 0.0874
Schistosoma mansoni hypothetical protein 0.004 0.0386 0.0398
Echinococcus granulosus geminin 0.0687 0.8696 0.8976
Brugia malayi G-protein coupled receptor 0.0088 0.1002 0.1016
Onchocerca volvulus 0.0088 0.1002 0.1012
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0069 0.0763 0.0786
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0134 0.0138
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trichomonas vaginalis CAMK family protein kinase 0.0379 0.4734 0.4886
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Schistosoma mansoni histamine h1 receptor 0.0088 0.1002 0.1034
Entamoeba histolytica hypothetical protein 0.007 0.0777 0.0802
Onchocerca volvulus 0.0029 0.0253 0.0237
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.008 0.0902 0.0925
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0056 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.078 0.0787
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0024 0.0005
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0199 0.0186
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.0428
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0012 0.0034 0.0029
Echinococcus granulosus biogenic amine 5HT receptor 0.0088 0.1002 0.1034
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0027 0.0217 0.02
Loa Loa (eye worm) oxidoreductase 0.0076 0.0853 0.0874
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0088 0.1002 0.1002
Loa Loa (eye worm) hypothetical protein 0.0041 0.0405 0.0411
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0011 0.0019 0.0087
Brugia malayi serine/threonine-protein kinase plk-2 0.0765 0.9688 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.007 0.078 0.0799
Echinococcus granulosus acetylcholinesterase 0.0495 0.6231 0.6431
Brugia malayi Doublecortin family protein 0.0039 0.0371 0.0364
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0134 0.0138
Echinococcus granulosus aldo keto reductase 0.0076 0.0853 0.088
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0312 0.0312
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0635 0.0656
Schistosoma mansoni cpg binding protein 0.0028 0.0237 0.0245
Mycobacterium tuberculosis Possible penicillin-binding protein 0.045 0.5647 1
Loa Loa (eye worm) ACC-1 protein 0.0054 0.0575 0.0588
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0011 0.0024 0.0039
Trypanosoma cruzi polo-like protein kinase, putative 0.0765 0.9688 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0019 0.002
Giardia lamblia Aldose reductase 0.0076 0.0853 0.088
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0011 0.0024 0.0005
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0054 0.0575 0.0594
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Mycobacterium leprae Conserved hypothetical protein 0.0011 0.0024 0.0072
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0134 0.0138
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0033 0.0298 0.0523
Brugia malayi RNA recognition motif domain containing protein 0.0028 0.024 0.0228
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0023 0.0176 0.0308
Onchocerca volvulus 0.0088 0.1002 0.1012
Mycobacterium ulcerans Type I modular polyketide synthase 0.0022 0.0158 0.0203
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0405 0.0418
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0025 0.0199 0.0199
Echinococcus multilocularis sex peptide receptor 0.0088 0.1002 0.1002
Plasmodium falciparum importin beta, putative 0.0035 0.032 0.1438
Brugia malayi Cytochrome P450 family protein 0.0024 0.0184 0.0171
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0635 0.0656
Trypanosoma cruzi aldo/keto reductase, putative 0.0076 0.0853 0.0862
Loa Loa (eye worm) hypothetical protein 0.0157 0.1893 0.1948
Schistosoma mansoni biogenic amine receptor 0.0088 0.1002 0.1034
Echinococcus granulosus acetylcholinesterase 0.0495 0.6231 0.6431
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0024
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0011 0.0024 0.011
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Schistosoma mansoni neuroligin 3 (S09 family) 0.0084 0.0951 0.0981
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0635 0.2851
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0635 0.0822
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Brugia malayi hypothetical protein 0.0118 0.1395 0.1422
Trypanosoma cruzi aldo-keto reductase 0.0076 0.0853 0.0862
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1131 0.1168
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0025 0.0192 0.0192
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0035 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0024
Echinococcus multilocularis somatostatin receptor 0.0088 0.1002 0.1002
Onchocerca volvulus 0.0039 0.0371 0.0359
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.078 0.0805
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1131 0.1131
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0237 0.0238
Loa Loa (eye worm) hypothetical protein 0.0012 0.0029 0.0024
Schistosoma mansoni smad1 5 8 and 0.0011 0.0024 0.0024
Schistosoma mansoni polycystin 1-related 0.0039 0.0371 0.0383
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0088 0.1002 0.1034
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0035 0.0323 0.0327
Schistosoma mansoni carbonic anhydrase-related 0.004 0.0393 0.0406
Brugia malayi AMP-binding enzyme family protein 0.002 0.014 0.0125
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0312 0.0303
Trichomonas vaginalis CAMK family protein kinase 0.0379 0.4734 0.4886
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0076 0.0853 0.2782
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0371 0.1667
Brugia malayi MH1 domain containing protein 0.0011 0.0024 0.0004
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0011 0.0024 0.0025
Echinococcus multilocularis segment polarity protein dishevelled 0.0012 0.0029 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0088 0.1002 0.1002
Schistosoma mansoni Smad4 0.0011 0.0024 0.0024
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0134 0.0138
Onchocerca volvulus Huntingtin homolog 0.008 0.0902 0.0908
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Brugia malayi beta-lactamase family protein 0.007 0.078 0.0787
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0011 0.0024 0.0025
Echinococcus multilocularis nAChR subunit 0.0029 0.0253 0.0253
Schistosoma mansoni adenoreceptor 0.0088 0.1002 0.1034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.0303
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Brugia malayi RNA, U transporter 1 0.0098 0.1138 0.1157
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0088 0.1002 0.1034
Schistosoma mansoni caspase-3 (C14 family) 0.0011 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Loa Loa (eye worm) hypothetical protein 0.003 0.0265 0.0267
Schistosoma mansoni smad 0.0011 0.0024 0.0024
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0011 0.0024 0.0019
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0058 0.0623 0.0624
Mycobacterium leprae Possible oxidoreductase 0.0022 0.016 0.0515
Echinococcus granulosus caspase 0.0011 0.0019 0.002
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0076 0.0853 0.0862
Trichomonas vaginalis aldo/keto reductase, putative 0.0076 0.0853 0.088
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0951 0.168
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0197 0.0183
Leishmania major protein kinase, putative 0.0014 0.0056 0.0056
Schistosoma mansoni sodium/chloride dependent transporter 0.0046 0.0465 0.048
Plasmodium vivax glutathione reductase, putative 0.0098 0.1132 0.5082
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0011 0.0024 0.0025
Trypanosoma brucei cAMP response protein 1, putative 0.0011 0.0024 0.0023
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0088 0.1002 0.1034
Plasmodium falciparum glutathione reductase 0.0034 0.0312 0.1401
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0014 0.0063 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0019 0.002
Echinococcus granulosus regulator of G protein signaling 7 0.0012 0.0029 0.003
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0054 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.1125 0.1161
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Loa Loa (eye worm) DIX domain-containing protein 0.0012 0.0029 0.0024
Leishmania major hypothetical protein, conserved 0.0011 0.0024 0.0023
Echinococcus granulosus cpg binding protein 0.003 0.0258 0.0266
Brugia malayi Cation transporter family protein 0.0054 0.0575 0.0575
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.078 0.0799
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0054 0.0575 0.0575
Schistosoma mansoni biogenic amine receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0433 0.0433
Mycobacterium tuberculosis Probable reductase 0.0223 0.274 0.485
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0022 0.0158 0.0277
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0951 0.0981
Loa Loa (eye worm) hypothetical protein 0.0171 0.2068 0.213
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0012 0.0029 0.001
Schistosoma mansoni lamin 0.0026 0.0214 0.0221
Echinococcus multilocularis carbonic anhydrase 0.004 0.0393 0.0393
Loa Loa (eye worm) LGC-31 protein 0.0054 0.0575 0.0588
Brugia malayi larval opioid receptor 0.0088 0.1002 0.1016
Loa Loa (eye worm) carboxylesterase 0.0084 0.0951 0.0975
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Brugia malayi beta-lactamase family protein 0.007 0.078 0.0787
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0025 0.0199 0.0186
Brugia malayi Carboxylesterase family protein 0.0084 0.0951 0.0963
Loa Loa (eye worm) hypothetical protein 0.0012 0.0033 0.0028
Brugia malayi G-protein coupled receptor 0.0088 0.1002 0.1016
Trichomonas vaginalis aldo/keto reductase, putative 0.0076 0.0853 0.088
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Brugia malayi CXXC zinc finger family protein 0.0028 0.0237 0.0225
Onchocerca volvulus Huntingtin homolog 0.008 0.0902 0.0908
Loa Loa (eye worm) hypothetical protein 0.0048 0.0494 0.0504
Loa Loa (eye worm) hypothetical protein 0.0039 0.0371 0.0377
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0371 0.0383
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0108 0.1267 0.129
Brugia malayi mbt repeat family protein 0.0027 0.0217 0.0205
Echinococcus multilocularis musashi 0.0026 0.0214 0.0214
Toxoplasma gondii type I fatty acid synthase, putative 0.0023 0.0176 0.0789
Leishmania major protein kinase, putative 0.0014 0.0056 0.0056
Echinococcus granulosus 7tm_1 domain containing protein 0.0088 0.1002 0.1034
Echinococcus granulosus cGMP dependent protein kinase 0.0014 0.0056 0.0058
Onchocerca volvulus 0.0255 0.3154 0.3239
Giardia lamblia DNA repair protein RAD52 0.0202 0.2467 0.2547
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0054 0.0575 0.0575
Echinococcus granulosus alpha 1A adrenergic receptor 0.0088 0.1002 0.1034
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0433 0.0447
Schistosoma mansoni lipoxygenase 0.0161 0.1944 0.2007
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0011 0.0024 0.0024
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.019 0.0196
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0088 0.1002 0.1034
Echinococcus granulosus carbonic anhydrase 0.004 0.0393 0.0406
Loa Loa (eye worm) hypothetical protein 0.002 0.0134 0.0132
Schistosoma mansoni glutaminase 0.061 0.7701 0.7949
Loa Loa (eye worm) hypothetical protein 0.007 0.078 0.0799
Mycobacterium ulcerans hypothetical protein 0.0011 0.0024 0.0029
Brugia malayi hypothetical protein 0.0025 0.0199 0.0186
Echinococcus multilocularis caspase 2 0.0037 0.0351 0.0351
Mycobacterium ulcerans transmembrane transport protein 0.0011 0.0024 0.0029
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0054 0.0575 0.0594
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.0212 0.0213
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0054 0.0575 0.0575
Echinococcus multilocularis L aminoadipate semialdehyde 0.0035 0.0322 0.0322
Mycobacterium ulcerans Type I modular polyketide synthase 0.0022 0.0158 0.0203
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0312 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0011 0.0019 0.0086
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.1132 0.1151
Echinococcus granulosus thioredoxin glutathione reductase 0.0098 0.1132 0.1169
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.1106 0.1142
Brugia malayi regulator of G-protein signaling egl-10 0.0012 0.0029 0.001
Echinococcus granulosus tm gpcr rhodopsin 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0183 0.2228 0.2294
Echinococcus granulosus SAM and MBT domain containing protein 0.0027 0.0217 0.0224
Loa Loa (eye worm) melatonin receptor type 1A 0.0088 0.1002 0.1028
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0255 0.3154 0.3242
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Loa Loa (eye worm) hypothetical protein 0.054 0.6802 0.7019
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0405 0.0405
Echinococcus granulosus cGMP dependent protein kinase 1 0.0014 0.0056 0.0058
Echinococcus granulosus glycine receptor subunit beta 0.0054 0.0575 0.0594
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0025 0.0199 0.0199
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0054 0.0575 0.0594
Onchocerca volvulus 0.0088 0.1002 0.1012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0371 0.0371
Brugia malayi Carboxylesterase family protein 0.0084 0.0951 0.0963
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0033 0.0298 0.0523
Onchocerca volvulus 0.0026 0.0208 0.019
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0018 0.0107 0.0186
Loa Loa (eye worm) hypothetical protein 0.0024 0.019 0.019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0088 0.1002 0.1002
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0023 0.0176 0.0308
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0312 0.1401
Echinococcus multilocularis G protein coupled receptor 139 0.0369 0.4605 0.4605
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trypanosoma cruzi Flagellar Member 6 0.0011 0.0024 0.0005
Toxoplasma gondii isocitrate dehydrogenase 0.0069 0.0763 0.3426
Echinococcus multilocularis dnaJ subfamily B 0.04 0.5004 0.5004
Schistosoma mansoni dishevelled 0.0012 0.0029 0.003
Mycobacterium ulcerans polyketide synthase Pks13 0.0033 0.0298 0.0383
Echinococcus multilocularis tar DNA binding protein 0.0028 0.024 0.024
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0024 0.0039
Schistosoma mansoni jumonji/arid domain-containing protein 0.0026 0.0212 0.0219
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0048 0.0494 0.2219
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0312 0.1401
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0013 0.0049 0.0218
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0058 0.0623 0.0643
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0054 0.0575 0.0575
Trypanosoma brucei PAB1-binding protein , putative 0.0183 0.2228 0.2298
Loa Loa (eye worm) hypothetical protein 0.0012 0.0033 0.0028
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0022 0.0158 0.0203
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Brugia malayi Latrophilin receptor protein 2 0.0171 0.2068 0.2119
Mycobacterium ulcerans thioesterase 0.0018 0.0111 0.0142
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0069 0.0763 0.3426
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0765 0.9688 1
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0011 0.0024 0.011
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0011 0.0024 0.0024
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0069 0.0763 0.0788
Echinococcus multilocularis acetylcholinesterase 0.0495 0.6231 0.6231
Echinococcus multilocularis snurportin 1 0.0369 0.461 0.461
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0011 0.0024 0.0005
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0433 0.0447
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0023 0.0176 0.0568
Loa Loa (eye worm) solute carrier family 6 member 4 0.0255 0.3154 0.3251
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0134 0.0138
Echinococcus multilocularis neuroligin 0.0084 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0037 0.0351 0.0356
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0011 0.0019 0.002
Schistosoma mansoni sex comb on midleg homolog 0.0027 0.0217 0.0224
Schistosoma mansoni jumonji/arid domain-containing protein 0.0026 0.0212 0.0219
Onchocerca volvulus 0.0088 0.1002 0.1012
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0951 0.0981
Onchocerca volvulus 0.0025 0.0199 0.0181
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0088 0.1002 0.1002
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.001 0.0002 0.001
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0011 0.0024 0.0025
Brugia malayi jmjC domain containing protein 0.0025 0.0192 0.0178
Trichomonas vaginalis ran, putative 0.0012 0.0034 0.0035
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0433 0.1946
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0134 0.0138
Entamoeba histolytica hypothetical protein 0.0057 0.0614 0.0634
Onchocerca volvulus 0.0706 0.8936 0.9221
Echinococcus multilocularis regulator of G protein signaling 7 0.0012 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Brugia malayi beta-lactamase 0.007 0.078 0.0787
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0014 0.006 0.0267
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Trypanosoma cruzi aldo/keto reductase, putative 0.0022 0.016 0.0145
Brugia malayi hypothetical protein 0.0043 0.0433 0.0428
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0088 0.1002 0.1002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Entamoeba histolytica aldose reductase, putative 0.0076 0.0853 0.088
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0635 0.0822
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0405 0.0418
Schistosoma mansoni hypothetical protein 0.004 0.0386 0.0398
Echinococcus multilocularis neuropeptides capa receptor 0.0088 0.1002 0.1002
Echinococcus multilocularis aldo keto reductase 0.0076 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0371 0.0371
Echinococcus granulosus neuropeptide receptor 0.0369 0.4605 0.4754
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0011 0.0024 0.0025
Brugia malayi NADH-dependent xylose reductase 0.0022 0.016 0.0145
Schistosoma mansoni amine GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0084 0.0951 0.0981
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0054 0.0575 0.0575
Brugia malayi ORL1-like opioid receptor 0.0088 0.1002 0.1016
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0025 0.0199 0.0199
Trypanosoma cruzi PAB1-binding protein , putative 0.0183 0.2228 0.2284
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0108 0.1267 0.129
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Brugia malayi hypothetical protein 0.0012 0.0029 0.001
Onchocerca volvulus 0.0029 0.0253 0.0237
Echinococcus multilocularis calcium activated potassium channel 0.0011 0.0019 0.0019
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.003 0.0265 0.0273
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0575 0.0575
Loa Loa (eye worm) carboxylesterase 0.0084 0.0951 0.0975
Schistosoma mansoni aldo-keto reductase 0.0076 0.0853 0.088
Leishmania major protein kinase A regulatory subunit, putative 0.0011 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0255 0.3154 0.3251
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Brugia malayi Carboxylesterase family protein 0.0495 0.6231 0.6424
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.002 0.0134 0.0134
Echinococcus multilocularis voltage gated potassium channel subunit 0.0022 0.016 0.016
Echinococcus granulosus allatostatin A receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis smad 0.0011 0.0024 0.0024
Echinococcus multilocularis allatostatin A receptor 0.0088 0.1002 0.1002
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Trypanosoma brucei metacaspase MCA2 0.0011 0.0019 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.078 0.0805
Leishmania major aldo-keto reductase-like protein 0.0076 0.0853 0.0878
Loa Loa (eye worm) hypothetical protein 0.005 0.0523 0.0534
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0014 0.0063 0.0079
Schistosoma mansoni acetylcholine receptor subunit beta 0.0025 0.0199 0.0206
Toxoplasma gondii aldo-keto reductase 0.0022 0.016 0.0717
Echinococcus granulosus hypothetical protein 0.0088 0.1002 0.1034
Echinococcus granulosus voltage gated potassium channel subunit 0.0022 0.016 0.0165
Schistosoma mansoni rab6-interacting 0.0039 0.0371 0.0383
Trypanosoma brucei hypothetical protein, conserved 0.007 0.078 0.0803
Echinococcus multilocularis carbonic anhydrase 0.004 0.0393 0.0393
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.1131 0.1162
Echinococcus multilocularis aldo keto reductase 0.0076 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Entamoeba histolytica aldose reductase, putative 0.0076 0.0853 0.088
Onchocerca volvulus Cell death protein 3 homolog 0.0037 0.0351 0.0338
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0088 0.1002 0.1034
Loa Loa (eye worm) norepinephrine transporter 0.0255 0.3154 0.3251
Schistosoma mansoni tar DNA-binding protein 0.0028 0.024 0.0248
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0054 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0088 0.1002 0.1028
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0635 0.0635
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0237 0.0225
Brugia malayi Cell death protein 3 precursor 0.0037 0.0351 0.0343
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.032 0.1438
Loa Loa (eye worm) beta-lactamase 0.007 0.078 0.0799
Schistosoma mansoni hypothetical protein 0.0088 0.1002 0.1034
Echinococcus multilocularis tumor protein p63 0.0329 0.4095 0.4095
Loa Loa (eye worm) acetylcholine receptor protein 0.0025 0.0199 0.0199
Echinococcus granulosus nAChR subunit 0.0029 0.0253 0.0261
Schistosoma mansoni transcription factor LCR-F1 0.007 0.0777 0.0802
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0312 0.0549
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Echinococcus multilocularis RUN 0.0039 0.0371 0.0371
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Echinococcus granulosus Pleckstrin G protein interacting region 0.0012 0.0029 0.003
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0312 0.7184
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0069 0.0763 0.1348
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0029 0.0253 0.0242
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis expressed conserved protein 0.0014 0.0056 0.0056
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0023 0.0176 0.0225
Toxoplasma gondii hypothetical protein 0.0043 0.0433 0.1946
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0022 0.016 0.0717
Onchocerca volvulus 0.0088 0.1002 0.1012
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0025 0.0199 0.0186
Echinococcus multilocularis G-protein coupled receptor, putative 0.0088 0.1002 0.1002
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0134 0.0132
Entamoeba histolytica hypothetical protein 0.007 0.0777 0.0802
Schistosoma mansoni hypothetical protein 0.0171 0.2068 0.2135
Loa Loa (eye worm) hypothetical protein 0.0035 0.032 0.0324
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0025 0.0192 0.0198
Mycobacterium tuberculosis Conserved protein 0.0022 0.016 0.0279
Echinococcus multilocularis neuropeptide Y receptor 0.0088 0.1002 0.1002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0248 0.306 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0393 0.0399
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0088 0.1002 0.1028
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0012 0.0034 0.0154
Onchocerca volvulus 0.0025 0.0199 0.0181
Loa Loa (eye worm) Smad1 0.0011 0.0024 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0575 0.0575
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.002 0.014 0.0244
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0016 0.0079 0.0136
Loa Loa (eye worm) hypothetical protein 0.0255 0.3154 0.3251
Echinococcus granulosus tm gpcr rhodopsin 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0248 0.3053 0.3147
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0076 0.0853 0.0878
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0076 0.0853 0.0862
Brugia malayi G protein-coupled receptor 0.0088 0.1002 0.1016
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Echinococcus multilocularis neuropeptides capa receptor 0.0088 0.1002 0.1002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0369 0.461 0.4755
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0371 0.1667
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0214 0.0201
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0312 0.032
Trichomonas vaginalis aldo/keto reductase, putative 0.0076 0.0853 0.088
Brugia malayi hypothetical protein 0.0039 0.0371 0.0364
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0253 0.0242
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0025 0.0199 0.0186
Echinococcus multilocularis serotonin receptor 0.0088 0.1002 0.1002
Echinococcus multilocularis serotonin transporter 0.0255 0.3154 0.3154
Plasmodium vivax importin-beta 2, putative 0.0035 0.032 0.1438
Onchocerca volvulus 0.0088 0.1002 0.1012
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0011 0.0019 0.0019
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0312 0.0322
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0433 0.0433
Brugia malayi sulfakinin receptor protein 0.0088 0.1002 0.1016
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0248 0.3053 0.3134
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0022 0.016 0.0163
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Onchocerca volvulus 0.0084 0.0951 0.0958
Schistosoma mansoni caspase-7 (C14 family) 0.0011 0.0019 0.002
Leishmania major hypothetical protein, conserved 0.0011 0.0024 0.0023
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0011 0.0024 0.0025
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0108 0.1267 0.129
Trypanosoma brucei trypanothione reductase 0.0098 0.1132 0.1167
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0011 0.0024 0.0024
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0022 0.0158 0.0277
Echinococcus granulosus regulator of G protein signaling 7 0.0012 0.0029 0.003
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0069 0.0763 0.0769
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0024 0.019 0.0177
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0088 0.1002 0.1012
Treponema pallidum cyclic nucleotide binding protein 0.0011 0.0024 0.007
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0765 0.9688 1
Brugia malayi RNA binding protein 0.0028 0.024 0.0228
Onchocerca volvulus 0.0048 0.0494 0.0486
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0022 0.0158 0.0511
Treponema pallidum cyclic nucleotide binding protein 0.0011 0.0024 0.007
Trypanosoma brucei C-8 sterol isomerase, putative 0.0307 0.3821 0.3942
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0011 0.0024 0.0025
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0011 0.0024 0.0025
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.002 0.0134 0.0138
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0312 0.0322
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0108 0.1267 0.1302
Mycobacterium ulcerans polyketide synthase 0.0023 0.0176 0.0225
Echinococcus granulosus serotonin transporter 0.0255 0.3154 0.3256
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0495 0.6231 0.6429
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0433 0.0428
Brugia malayi G protein-coupled receptor F59B2.13 0.0088 0.1002 0.1016
Brugia malayi Tachykinin-like peptides receptor 99D 0.0088 0.1002 0.1016
Echinococcus granulosus L aminoadipate semialdehyde 0.0035 0.0322 0.0333
Onchocerca volvulus 0.0076 0.0853 0.0857
Echinococcus multilocularis geminin 0.0687 0.8696 0.8696
Echinococcus granulosus apoptotic protease activating factor 1 0.0026 0.0208 0.0215
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Loa Loa (eye worm) hypothetical protein 0.0039 0.0371 0.0377
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0069 0.0763 0.0763
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0312 0.1401
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0023 0.0176 0.0308
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0202 0.2467 0.2547
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0011 0.0024 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.078 0.0787
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0024 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.019 0.0196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1131 0.1168
Leishmania major hypothetical protein, conserved 0.0183 0.2228 0.2298
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Schistosoma mansoni biogenic amine receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis serotonin receptor 0.0088 0.1002 0.1002
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0371 0.0377
Schistosoma mansoni hypothetical protein 0.0088 0.1002 0.1034
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0057 0.0039
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trypanosoma cruzi PAB1-binding protein , putative 0.0183 0.2228 0.2284
Entamoeba histolytica hypothetical protein 0.001 0.0002 0.0002
Schistosoma mansoni myosin xvIII 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.1106 0.1124
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.002 0.0134 0.0138
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0433 0.0447
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.078 0.1378
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0088 0.1002 0.1034
Onchocerca volvulus 0.0054 0.0575 0.057
Schistosoma mansoni dishevelled 0.0012 0.0029 0.003
Loa Loa (eye worm) glutaminase 0.061 0.7701 0.7947
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.002 0.0134 0.0134
Plasmodium vivax amine transporter, putative 0.0043 0.0433 0.1946
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Onchocerca volvulus 0.0088 0.1002 0.1012
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0054 0.0575 0.0588
Echinococcus granulosus polycomb protein SCMH1 0.0027 0.0217 0.0224
Brugia malayi Carboxylesterase family protein 0.0084 0.0951 0.0963
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0069 0.0763 0.0786
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0575 0.0594
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0054 0.0575 0.0575
Onchocerca volvulus 0.007 0.078 0.0782
Mycobacterium leprae Conserved hypothetical protein 0.0054 0.057 0.1857
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0022 0.016 0.0165
Brugia malayi TAR-binding protein 0.0028 0.024 0.0228
Onchocerca volvulus 0.002 0.014 0.012
Plasmodium falciparum aldo-keto reductase, putative 0.0022 0.016 0.0717
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0559 0.251
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0575 0.0575
Brugia malayi Cation transporter family protein 0.0054 0.0575 0.0575
Trypanosoma brucei prostaglandin f synthase 0.0076 0.0853 0.0878
Schistosoma mansoni hypothetical protein 0.0687 0.8696 0.8976
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.004 0.0041
Onchocerca volvulus 0.0054 0.0575 0.057
Onchocerca volvulus 0.0084 0.0951 0.0958
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.0303
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trypanosoma cruzi polo-like protein kinase, putative 0.0765 0.9688 1
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.078 0.0805
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Brugia malayi N-terminal motif family protein 0.0248 0.3053 0.3138
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.003 0.0265 0.0254
Echinococcus multilocularis g protein coupled receptor 0.0088 0.1002 0.1002
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0237 0.0244
Mycobacterium ulcerans polyketide synthase Pks9 0.0014 0.0063 0.0079
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Onchocerca volvulus 0.0035 0.0322 0.0308
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.004 0.0393 0.0387
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.1002 0.1034
Schistosoma mansoni sodium/chloride dependent transporter 0.0255 0.3154 0.3256
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0255 0.3154 0.3256
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0035 0.0323 0.0333
Echinococcus granulosus carbonic anhydrase 0.004 0.0393 0.0406
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0012 0.0037 0.0062
Plasmodium falciparum transporter, putative 0.0043 0.0433 0.1946
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.1634 0.1634
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0054 0.0575 0.0575
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0011 0.0024 0.0005
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Onchocerca volvulus 0.0054 0.0575 0.057
Echinococcus multilocularis segment polarity protein dishevelled 0.0012 0.0029 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0248 0.306 0.5416
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0108 0.1267 0.1308
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0088 0.1002 0.1028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0069 0.0763 0.0763
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.032
Schistosoma mansoni opsin-like receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0214 0.0214
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0184 0.0184
Schistosoma mansoni neuropeptide f receptor 76f 0.0088 0.1002 0.1034
Brugia malayi Serotonin receptor 0.0088 0.1002 0.1016
Schistosoma mansoni hypothetical protein 0.0026 0.0208 0.0215
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0248 0.306 0.5416
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0253 0.0242
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0253 0.0261
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0312 0.0322
Schistosoma mansoni regulator of G protein signaling 0.0012 0.0029 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0369 0.4611 0.4749
Onchocerca volvulus 0.0088 0.1002 0.1012
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0433 0.0447
Echinococcus multilocularis para nitrobenzyl esterase 0.0084 0.0951 0.0951
Onchocerca volvulus 0.0038 0.0367 0.0354
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.004 0.0385 0.0397
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0575 0.0575
Schistosoma mansoni ran 0.0012 0.0034 0.0035
Echinococcus multilocularis neuropeptide receptor A26 0.0088 0.1002 0.1002
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0024 0.0018
Toxoplasma gondii ABC1 family protein 0.007 0.078 0.3502
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0011 0.0024 0.0513
Schistosoma mansoni neuropeptide F-like receptor 0.0088 0.1002 0.1034
Mycobacterium tuberculosis Conserved protein 0.007 0.078 0.1378
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0433 0.1946
Echinococcus granulosus G protein coupled receptor 139 0.0088 0.1002 0.1034
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0056 0.0058
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0088 0.1002 0.1028
Onchocerca volvulus 0.0054 0.0575 0.057
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0018 0.0103 0.0131
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0011 0.0024 0.011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Schistosoma mansoni tar DNA-binding protein 0.0028 0.024 0.0248
Schistosoma mansoni carbonic anhydrase-related 0.004 0.0393 0.0406
Entamoeba histolytica alcohol dehydrogenase, putative 0.0022 0.016 0.0165
Mycobacterium tuberculosis Probable thioesterase TesA 0.0018 0.0111 0.0193
Loa Loa (eye worm) oxidoreductase 0.0076 0.0853 0.0874
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0575 0.0575
Plasmodium vivax aldehyde reductase, putative 0.0022 0.016 0.0717
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.1634 0.1686
Echinococcus multilocularis SAM and MBT domain containing protein 0.0027 0.0217 0.0217
Trichomonas vaginalis aldo-keto reductase, putative 0.0022 0.016 0.0165
Echinococcus multilocularis histone acetyltransferase MYST2 0.003 0.0265 0.0265
Brugia malayi hypothetical protein 0.0012 0.0029 0.001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Schistosoma mansoni hypothetical protein 0.004 0.0386 0.0398
Toxoplasma gondii hypothetical protein 0.0012 0.0029 0.0132
Brugia malayi Carboxylesterase family protein 0.0495 0.6231 0.6424
Schistosoma mansoni nAChR subunit 0.0025 0.0199 0.0206
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0641 0.0661
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Brugia malayi Cyclic-nucleotide gated cation channel 0.002 0.0134 0.0119
Schistosoma mansoni voltage-gated potassium channel 0.0063 0.0679 0.0701
Onchocerca volvulus 0.0026 0.0214 0.0196
Brugia malayi hypothetical protein 0.0084 0.0951 0.0963
Echinococcus granulosus g protein coupled receptor 0.0088 0.1002 0.1034
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Schistosoma mansoni neuropeptide receptor 0.0088 0.1002 0.1034
Echinococcus granulosus carbonic anhydrase II 0.0108 0.1267 0.1308
Schistosoma mansoni biogenic amine (5HT) receptor 0.0088 0.1002 0.1034
Schistosoma mansoni hypothetical protein 0.0687 0.8696 0.8976
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0076 0.0853 0.0878
Echinococcus multilocularis fmrfamide receptor 0.0088 0.1002 0.1002
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0024 0.0018
Schistosoma mansoni hypothetical protein 0.0011 0.0024 0.0025
Brugia malayi MH2 domain containing protein 0.0168 0.2029 0.2079
Mycobacterium ulcerans hypothetical protein 0.0022 0.016 0.0204
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.078 0.0805
Plasmodium falciparum metacaspase-like protein 0.0011 0.0019 0.0087
Loa Loa (eye worm) isocitrate dehydrogenase 0.0069 0.0763 0.0782
Echinococcus granulosus carbonic anhydrase 0.004 0.0393 0.0406
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni opsin-like receptor 0.0088 0.1002 0.1034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Mycobacterium leprae Polyketide synthase Pks13 0.0033 0.0298 0.0966
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.004 0.0393 0.0387
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Schistosoma mansoni lipoxygenase 0.023 0.2834 0.2925
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0054 0.0575 0.0594
Onchocerca volvulus 0.0028 0.0237 0.022
Echinococcus granulosus neuropeptide receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis sodium and chloride dependent glycine 0.0043 0.0433 0.0433
Schistosoma mansoni acetylcholine receptor-related 0.0025 0.0199 0.0206
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0433 0.0447
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0171 0.2068 0.2119
Plasmodium falciparum ataxin-2 like protein, putative 0.0183 0.2228 1
Onchocerca volvulus 0.0039 0.0371 0.0359
Echinococcus multilocularis carboxylesterase 5A 0.0495 0.6231 0.6231
Loa Loa (eye worm) AGC/PKG protein kinase 0.0014 0.0056 0.0052
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0433 0.0433
Mycobacterium tuberculosis Conserved protein 0.007 0.078 0.1378
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.078 0.1378
Echinococcus granulosus neuropeptide receptor A26 0.0088 0.1002 0.1034
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0105 0.1218 0.1257
Schistosoma mansoni hypothetical protein 0.007 0.0777 0.0802
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0011 0.0024 0.011
Echinococcus granulosus tar DNA binding protein 0.0028 0.024 0.0248
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.0777 0.0802
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Schistosoma mansoni neurotransmitter gated ion channel 0.0025 0.0199 0.0206
Mycobacterium ulcerans glutaminase 0.061 0.7701 1
Echinococcus multilocularis expressed conserved protein 0.009 0.1032 0.1032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.0777 0.0777
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0018 0.0103 0.0131
Echinococcus granulosus expressed conserved protein 0.009 0.1032 0.1065
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0035 0.0322 0.0333
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0084 0.0951 0.0981
Brugia malayi Thioredoxin reductase 0.0098 0.1132 0.1151
Brugia malayi MH1 domain containing protein 0.0011 0.0024 0.0004
Schistosoma mansoni neuropeptide receptor 0.0088 0.1002 0.1034
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0011 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Schistosoma mansoni kinase 0.0389 0.4863 0.502
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0199 0.0186
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0223 0.274 0.485
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Loa Loa (eye worm) hypothetical protein 0.0026 0.0208 0.0209
Echinococcus granulosus serotonin receptor 0.0088 0.1002 0.1034
Trypanosoma cruzi cAMP binding protein, putative 0.0011 0.0024 0.0005
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0575 0.0575
Echinococcus granulosus glycine receptor subunit beta 0.0054 0.0575 0.0594
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0134 0.0138
Onchocerca volvulus 0.0076 0.0853 0.0857
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0076 0.0853 0.0874
Onchocerca volvulus 0.0022 0.016 0.014
Echinococcus granulosus mothers against decapentaplegic 5 0.0011 0.0024 0.0024
Trypanosoma brucei Flagellar Member 6 0.0011 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Onchocerca volvulus Fatty acid synthase homolog 0.004 0.0384 0.0372
Brugia malayi hypothetical protein 0.0025 0.0199 0.0186
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0021 0.015 0.0261
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0171 0.2068 0.2135
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0312 0.0322
Schistosoma mansoni hypothetical protein 0.0369 0.461 0.4759
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0023 0.0176 0.0568
Echinococcus multilocularis carbonic anhydrase 0.004 0.0393 0.0393
Plasmodium falciparum glutathione reductase 0.0098 0.1132 0.5082
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0088 0.1002 0.1016
Toxoplasma gondii aldose reductase, putative 0.0076 0.0853 0.3828
Echinococcus granulosus segment polarity protein dishevelled 0.0012 0.0029 0.003
Schistosoma mansoni tar DNA-binding protein 0.0028 0.024 0.0248
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0012 0.0034 0.0154
Mycobacterium ulcerans beta-lactamase 0.007 0.078 0.101
Echinococcus granulosus voltage gated potassium channel 0.0024 0.019 0.0196
Echinococcus granulosus sex peptide receptor 0.0088 0.1002 0.1034
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0054 0.0575 0.0594
Echinococcus granulosus BC026374 protein S09 family 0.0084 0.0951 0.0981
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0054 0.0575 0.0575
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0312 0.1401
Trypanosoma brucei aldo/keto reductase, putative 0.0022 0.016 0.0163
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0088 0.1002 0.1002
Loa Loa (eye worm) glutaminase 2 0.061 0.7701 0.7947
Trichomonas vaginalis esterase, putative 0.007 0.078 0.0805
Leishmania major hypothetical protein, unknown function 0.0011 0.0024 0.0023
Schistosoma mansoni pol-related 0.0076 0.0853 0.088
Mycobacterium leprae Probable lipase LipE 0.007 0.078 0.2544
Loa Loa (eye worm) hypothetical protein 0.0011 0.0024 0.0019
Echinococcus multilocularis aldehyde reductase 0.0054 0.057 0.057
Schistosoma mansoni hypothetical protein 0.0088 0.1002 0.1034
Onchocerca volvulus 0.0084 0.0951 0.0958
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.023 0.2834 0.2834
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0134 0.0138
Loa Loa (eye worm) pigment dispersing factor receptor c 0.054 0.6802 0.7019
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0022 0.016 0.0717
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0011 0.0019 0.0087
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0575 0.0594
Plasmodium vivax thioredoxin reductase, putative 0.0098 0.1132 0.5082
Leishmania major trypanothione reductase 0.0098 0.1132 0.1167
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Schistosoma mansoni neuropeptide receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0011 0.0024 0.0025
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0011 0.0024 0.0039
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0054 0.0575 0.0594
Brugia malayi isocitrate dehydrogenase 0.0069 0.0763 0.0769
Schistosoma mansoni hypothetical protein 0.0039 0.0371 0.0383
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0012 0.0034 0.0035
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Brugia malayi glutathione reductase 0.0098 0.1132 0.1151
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0019 0.0087
Toxoplasma gondii hypothetical protein 0.0043 0.0433 0.1946
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0069 0.0763 0.0763
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0058 0.0623 0.0637
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.078 0.0805
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.004 0.0385 0.0397
Echinococcus granulosus GTP binding nuclear protein Ran 0.0012 0.0034 0.0035
Leishmania major carbonic anhydrase-like protein 0.0108 0.1267 0.1306
Loa Loa (eye worm) hypothetical protein 0.0029 0.0253 0.0255
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0011 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0706 0.8936 0.9223
Onchocerca volvulus 0.0084 0.0951 0.0958
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0076 0.0853 0.088
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0088 0.1002 0.1002
Schistosoma mansoni hypothetical protein 0.0082 0.0931 0.0961
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Brugia malayi Cation transporter family protein 0.0054 0.0575 0.0575
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0197 0.0183
Giardia lamblia Kinase, PLK 0.0765 0.9688 1
Schistosoma mansoni hypothetical protein 0.0369 0.4611 0.476
Schistosoma mansoni nAChR subunit 0.0025 0.0199 0.0206
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0088 0.1002 0.1002
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0054 0.0575 0.0588
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0025 0.0199 0.0206
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.001 0.0002 0.001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.078 0.1378
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.004 0.0385 0.0385
Schistosoma mansoni carbonic anhydrase-related 0.004 0.0393 0.0406
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0054 0.0575 0.0594
Echinococcus granulosus dnaJ subfamily B 0.04 0.5004 0.5165
Loa Loa (eye worm) neuropeptide F receptor 0.0088 0.1002 0.1028
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0011 0.0024 0.011
Loa Loa (eye worm) G-protein coupled receptor 0.0088 0.1002 0.1028
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0058 0.0623 0.0623
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0011 0.0024 0.0025
Echinococcus granulosus aldo keto reductase 0.0076 0.0853 0.088
Loa Loa (eye worm) hypothetical protein 0.0369 0.4611 0.4756
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.004 0.0393 0.0387
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0054 0.0575 0.0575
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Echinococcus granulosus orexin receptor type 2 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0011 0.0024 0.0005
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.0441
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0011 0.0024 0.0025
Onchocerca volvulus Neuropeptide F receptor homolog 0.0088 0.1002 0.1012
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0024 0.019 0.0196
Mycobacterium ulcerans hypothetical protein 0.0011 0.0024 0.0029
Schistosoma mansoni gliotactin 0.0084 0.0951 0.0981
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0076 0.0853 0.0862
Echinococcus granulosus neuropeptide FF receptor 2 0.0088 0.1002 0.1034
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0312 0.032
Onchocerca volvulus Serine\/threonine kinase homolog 0.0765 0.9688 1
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0214 0.0214
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.005 0.0513 0.053
Treponema pallidum catabolite gene activator (Crp) 0.0011 0.0024 0.007
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0082 0.0931 0.0961
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0405 0.0418
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0084 0.0951 0.0981
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0047 0.0476 0.0485
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0011 0.0019 0.002
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0012 0.0026 0.0041
Echinococcus multilocularis neuropeptide Y receptor 0.0088 0.1002 0.1002
Echinococcus granulosus patatin phospholipase domain containing protein 0.0011 0.0024 0.0025
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0312 0.0402
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0635 0.0822
Loa Loa (eye worm) hypothetical protein 0.007 0.078 0.0799
Brugia malayi hypothetical protein 0.0706 0.8936 0.9222
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0199 0.0186
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Schistosoma mansoni nAChR subunit 0.0054 0.0575 0.0594
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Loa Loa (eye worm) latrophilin receptor protein 2 0.0171 0.2068 0.213
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0057 0.0053
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Entamoeba histolytica hypothetical protein 0.0028 0.0237 0.0244
Schistosoma mansoni BC026374 protein (S09 family) 0.0084 0.0951 0.0981
Loa Loa (eye worm) hypothetical protein 0.0035 0.0322 0.0326
Echinococcus granulosus calcium activated potassium channel 0.0011 0.0019 0.0019
Entamoeba histolytica hypothetical protein 0.007 0.0777 0.0802
Echinococcus multilocularis polycomb protein SCMH1 0.0027 0.0217 0.0217
Onchocerca volvulus 0.0088 0.1002 0.1012
Leishmania major cyclic nucleotide-binding protein-like protein 0.0011 0.0024 0.0023
Brugia malayi AKH receptor 0.0088 0.1002 0.1016
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0312 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Loa Loa (eye worm) hypothetical protein 0.0026 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0029
Brugia malayi hypothetical protein 0.007 0.0777 0.0783
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0028 0.024 0.0241
Echinococcus multilocularis dro:myosuppressin receptor 0.0088 0.1002 0.1002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0013
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0088 0.1002 0.1016
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.078 0.0787
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0022 0.0158 0.0277
Echinococcus granulosus caspase 2 0.0037 0.0351 0.0362
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Echinococcus multilocularis glycine receptor subunit beta 0.0054 0.0575 0.0575
Echinococcus multilocularis neuropeptide FF receptor 2 0.0088 0.1002 0.1002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0088 0.1002 0.1002
Echinococcus granulosus nAChR subunit 0.0054 0.0575 0.0594
Echinococcus granulosus tumor protein p63 0.0329 0.4095 0.4227
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0014 0.0061 0.0063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1131 0.1168
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus granulosus GPCR family 2 0.0171 0.2068 0.2135
Schistosoma mansoni acetylcholinesterase 0.0084 0.0951 0.0981
Onchocerca volvulus 0.0088 0.1002 0.1012
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0019 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0019 0.002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0025 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0037 0.035 0.0354
Echinococcus multilocularis cpg binding protein 0.003 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trichomonas vaginalis glutaminase, putative 0.061 0.7701 0.7949
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0134 0.0132
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0035 0.0323 0.0314
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0171 0.2068 0.2135
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0069 0.0763 0.0763
Onchocerca volvulus 0.0076 0.0853 0.0857
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0018 0.0111 0.0357
Schistosoma mansoni amine GPCR 0.0088 0.1002 0.1034
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0134 0.0134
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0011 0.0024 0.0025
Schistosoma mansoni opsin-like receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0011 0.0024 0.0024
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.054 0.6802 0.7015
Schistosoma mansoni hypothetical protein 0.0171 0.2068 0.2135
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0134 0.0138
Mycobacterium tuberculosis Probable dehydrogenase 0.0223 0.274 0.485
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.1002 0.1034
Echinococcus granulosus g-protein coupled receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.1106 0.1106
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0635 0.0653
Brugia malayi hypothetical protein 0.0025 0.0199 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Brugia malayi neuropeptide F receptor 0.0088 0.1002 0.1016
Schistosoma mansoni ran 0.0012 0.0034 0.0035
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0069 0.0763 0.0786
Leishmania major regulatory subunit of protein kinase a-like protein 0.0011 0.0024 0.0023
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0076 0.0853 0.088
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0088 0.1002 0.1002
Echinococcus multilocularis glycine receptor subunit beta 0.0054 0.0575 0.0575
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0371 0.0371
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0575 0.0575
Echinococcus multilocularis protein dispatched 1 0.0047 0.0479 0.0479
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Echinococcus multilocularis aldo keto reductase 0.0076 0.0853 0.0853
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1131 0.1168
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0012 0.0029 0.0024
Schistosoma mansoni dep domain containing protein 0.0012 0.0029 0.003
Plasmodium falciparum metacaspase 1 0.0011 0.0019 0.0087
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Schistosoma mansoni hypothetical protein 0.0171 0.2068 0.2135
Echinococcus granulosus neuropeptide s receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0307 0.3821 0.394
Schistosoma mansoni aldo-keto reductase 0.0076 0.0853 0.088
Onchocerca volvulus 0.0088 0.1002 0.1012
Brugia malayi MH2 domain containing protein 0.0011 0.0024 0.0004
Schistosoma mansoni hypothetical protein 0.0088 0.1002 0.1034
Onchocerca volvulus 0.0088 0.1002 0.1012
Loa Loa (eye worm) hypothetical protein 0.0255 0.3154 0.3251
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0054 0.0575 0.0588
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0371 0.0383
Echinococcus multilocularis mothers against decapentaplegic 5 0.0011 0.0024 0.0024
Mycobacterium tuberculosis Conserved protein 0.007 0.078 0.1378
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.032 0.0328
Brugia malayi hypothetical protein 0.0039 0.0371 0.0364
Brugia malayi Dopamine receptor 0.0088 0.1002 0.1016
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.078 0.0805
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0011 0.0024 0.0024
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0223 0.274 0.485
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Onchocerca volvulus 0.0026 0.0214 0.0196
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0012 0.0029 0.003
Loa Loa (eye worm) hypothetical protein 0.0294 0.3646 0.3759
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0312 0.032
Loa Loa (eye worm) TYRA-2 protein 0.0088 0.1002 0.1028
Trichomonas vaginalis aldo-keto reductase, putative 0.0022 0.016 0.0165
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0011 0.0024 0.0025
Onchocerca volvulus 0.0076 0.0853 0.0857
Loa Loa (eye worm) hypothetical protein 0.0043 0.0433 0.0441
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0765 0.9688 1
Echinococcus multilocularis neuropeptide receptor 0.0088 0.1002 0.1002
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.001 0.0002 0.001
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0575 0.0594
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0024 0.019 0.019
Entamoeba histolytica aldose reductase, putative 0.0076 0.0853 0.088
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.078 0.0805
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0088 0.1002 0.1002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0012 0.0034 0.0015
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0319 0.3968 0.4084
Plasmodium falciparum thioredoxin reductase 0.0034 0.0312 0.1401
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0088 0.1002 0.1016
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.1946
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0022 0.0158 0.0511
Plasmodium falciparum ataxin-2 like protein, putative 0.0183 0.2228 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0054 0.0575 0.0575
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0312 0.0402
Echinococcus granulosus aldo keto reductase 0.0076 0.0853 0.088
Echinococcus granulosus biogenic amine 5HT receptor 0.0088 0.1002 0.1034
Schistosoma mansoni neurotransmitter gated ion channel 0.0025 0.0199 0.0206
Brugia malayi Serotonin receptor 0.0088 0.1002 0.1016
Entamoeba histolytica Ran family GTPase 0.0012 0.0034 0.0035
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0088 0.1002 0.1028
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0054 0.0575 0.0594
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0012 0.0029 0.0029
Loa Loa (eye worm) MBCTL1 0.003 0.0265 0.0267
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Loa Loa (eye worm) oxidoreductase 0.0076 0.0853 0.0874
Trypanosoma brucei metacaspase MCA3 0.0011 0.0019 0.0018
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0088 0.1002 0.1016
Mycobacterium tuberculosis Probable oxidoreductase 0.0076 0.0853 0.1507
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0635 0.1121
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0433 0.0433
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0312 0.032
Loa Loa (eye worm) hypothetical protein 0.0054 0.0575 0.0588
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0312 0.1401
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Brugia malayi intermediate filament protein 0.0026 0.0214 0.0201
Loa Loa (eye worm) hypothetical protein 0.0319 0.3968 0.4091
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Echinococcus granulosus lamin 0.0026 0.0214 0.0221
Leishmania major prostaglandin f synthase, putative 0.0076 0.0853 0.0878
Plasmodium falciparum aldehyde reductase, putative 0.0022 0.016 0.0717
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0312 0.1401
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus multilocularis nAChR subunit 0.0054 0.0575 0.0575
Echinococcus multilocularis aldo keto reductase 0.0076 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.0013 0.004 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0183 0.2228 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.004 0.0385 0.0397
Mycobacterium ulcerans Type I modular polyketide synthase 0.0022 0.0158 0.0203
Mycobacterium ulcerans carboxylesterase, LipT 0.0084 0.0951 0.1232
Onchocerca volvulus 0.0054 0.0575 0.057
Echinococcus multilocularis lamin 0.0026 0.0214 0.0214
Echinococcus granulosus lamin dm0 0.0026 0.0214 0.0221
Brugia malayi putative neuropeptide receptor NPR1 0.0088 0.1002 0.1016
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0495 0.6231 0.6431
Schistosoma mansoni lamin 0.0026 0.0214 0.0221
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Schistosoma mansoni amine GPCR 0.0088 0.1002 0.1034
Mycobacterium ulcerans oxidoreductase 0.0076 0.0853 0.1105
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0575 0.0594
Mycobacterium ulcerans regulatory protein 0.0011 0.0024 0.0029
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0069 0.0763 0.0769
Echinococcus multilocularis neuropeptide s receptor 0.0088 0.1002 0.1002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0014 0.0056 0.0056
Mycobacterium tuberculosis Probable hydrolase 0.007 0.078 0.1378
Brugia malayi CHE-14 protein 0.0041 0.0405 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Echinococcus granulosus neuropeptide Y receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0054 0.0575 0.0588
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0433 0.0447
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0011 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.004 0.0386 0.0398
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0218
Echinococcus multilocularis carbonic anhydrase II 0.0108 0.1267 0.1267
Echinococcus granulosus Smad4 0.0011 0.0024 0.0024
Echinococcus granulosus sodium and chloride dependent glycine 0.0043 0.0433 0.0447
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0076 0.0853 0.0862
Schistosoma mansoni voltage-gated potassium channel 0.0063 0.0679 0.0701
Onchocerca volvulus 0.0027 0.0217 0.02
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0223 0.274 0.485
Schistosoma mansoni rab6-interacting 0.0039 0.0371 0.0383
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Onchocerca volvulus 0.007 0.078 0.0782
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0012 0.0034 0.0015
Trypanosoma cruzi cAMP response protein 1, putative 0.0011 0.0024 0.0005
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0054 0.0575 0.0594
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.1131 0.115
Entamoeba histolytica hypothetical protein 0.0029 0.0253 0.0261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Echinococcus granulosus carboxylesterase 5A 0.0495 0.6231 0.6431
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0012 0.0034 0.0015
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0084 0.0951 0.168
Trypanosoma brucei carbonic anhydrase-like protein 0.0108 0.1267 0.1306
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.003 0.0265 0.0265
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.032 0.0328
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0054 0.0575 0.0594
Mycobacterium ulcerans thioesterase TesA 0.0018 0.0111 0.0142
Schistosoma mansoni smad1 5 8 and 0.0011 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.004 0.0393 0.0406
Onchocerca volvulus 0.0088 0.1002 0.1012
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0765 0.9688 0.9688
Brugia malayi RE15519p 0.0088 0.1002 0.1016
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0076 0.0853 0.088
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0088 0.1002 0.1034
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.078 0.1378
Onchocerca volvulus 0.0025 0.0199 0.0181
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Schistosoma mansoni myelin transcription factor 1 myt1 0.003 0.0265 0.0273
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0012 0.0029 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Brugia malayi mbt repeat family protein 0.0027 0.0217 0.0205
Brugia malayi Smad1 0.0011 0.0024 0.0004
Loa Loa (eye worm) hypothetical protein 0.007 0.078 0.0799
Onchocerca volvulus 0.0054 0.0575 0.057
Brugia malayi neuropeptide F receptor 0.0088 0.1002 0.1016
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.007 0.078 0.0799
Schistosoma mansoni growth hormone secretagogue receptor 0.0088 0.1002 0.1034
Echinococcus granulosus somatostatin receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) serotonin transporter b 0.0255 0.3154 0.3251
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002
Echinococcus multilocularis caspase 8 0.0011 0.0019 0.0019
Trypanosoma cruzi protein kinase A regulatory subunit 0.0011 0.0024 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) hypothetical protein 0.0495 0.6231 0.6429
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.1946
Echinococcus multilocularis neuropeptide receptor 0.0369 0.4605 0.4605
Schistosoma mansoni biogenic amine (5HT) receptor 0.0088 0.1002 0.1034
Schistosoma mansoni patched 1 0.0041 0.0405 0.0418
Treponema pallidum sodium- and chloride- dependent transporter 0.0255 0.3154 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0054 0.0575 0.0588
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0025 0.0199 0.0206
Schistosoma mansoni caspase-7 (C14 family) 0.0037 0.0351 0.0362
Mycobacterium ulcerans polyketide synthase 0.0022 0.0158 0.0203
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0108 0.1267 0.1308
Echinococcus granulosus smad 0.0011 0.0024 0.0024
Echinococcus multilocularis lysine specific demethylase 5A 0.0025 0.0192 0.0192
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0312 0.0322
Loa Loa (eye worm) hypothetical protein 0.004 0.0393 0.0399
Loa Loa (eye worm) hypothetical protein 0.007 0.078 0.0799
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0011 0.0024 0.0005
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.1002 0.1034
Trypanosoma brucei aldo-keto reductase, putative 0.0076 0.0853 0.0878
Echinococcus granulosus neuropeptides capa receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) neuropeptide F receptor 0.0088 0.1002 0.1028
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0635 0.0656
Trichomonas vaginalis aldo-keto reductase, putative 0.0022 0.016 0.0165
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0307 0.3821 0.3932
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.016 0.0165
Schistosoma mansoni intermediate filament proteins 0.0026 0.0214 0.0221
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0312 0.0402
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.1002 0.1034
Treponema pallidum catabolite gene activator 0.0011 0.0024 0.007
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0011 0.0024 0.0025
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0023 0.0176 0.0225
Echinococcus granulosus neuroligin 0.0084 0.0951 0.0981
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Brugia malayi hypothetical protein 0.0026 0.0208 0.0196
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.078 0.101
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.078 0.1378
Loa Loa (eye worm) MH2 domain-containing protein 0.0168 0.2029 0.2089
Loa Loa (eye worm) G-protein coupled receptor 0.0088 0.1002 0.1028
Schistosoma mansoni smad1 5 8 and 0.0011 0.0024 0.0024
Echinococcus multilocularis acetylcholinesterase 0.0495 0.6231 0.6231
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0011 0.0024 0.011
Onchocerca volvulus 0.0012 0.0029 0.0005
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0134 0.0138
Echinococcus granulosus g protein coupled receptor 0.0088 0.1002 0.1034
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.001 0.0002 0.001
Echinococcus multilocularis Smad4 0.0011 0.0024 0.0024
Echinococcus granulosus caspase 8 0.0011 0.0019 0.002
Brugia malayi follicle stimulating hormone receptor 0.0088 0.1002 0.1016
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0011 0.0024 0.0025
Schistosoma mansoni potassium channel beta 0.0022 0.016 0.0165
Schistosoma mansoni amine GPCR 0.0088 0.1002 0.1034
Loa Loa (eye worm) RNA binding protein 0.0028 0.024 0.0241
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.078 0.101
Brugia malayi Egg laying defective protein 4 0.0014 0.0056 0.0038
Mycobacterium ulcerans lipase LipD 0.007 0.078 0.101
Brugia malayi MH2 domain containing protein 0.0011 0.0024 0.0004
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1131 0.1131
Giardia lamblia Aldose reductase 0.0076 0.0853 0.088
Mycobacterium leprae conserved hypothetical protein 0.007 0.078 0.2544
Echinococcus multilocularis fmrfamide receptor 0.0088 0.1002 0.1002
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0433 0.0447
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0088 0.1002 0.1016
Plasmodium falciparum cGMP-dependent protein kinase 0.0014 0.0056 0.0253
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0011 0.0024 0.0023
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0076 0.0853 0.0853
Loa Loa (eye worm) hypothetical protein 0.004 0.0385 0.0391
Echinococcus multilocularis protein patched 0.0041 0.0405 0.0405
Mycobacterium ulcerans hypothetical protein 0.007 0.078 0.101
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0312 0.032
Brugia malayi jmjC domain containing protein 0.0026 0.0212 0.02
Brugia malayi hypothetical protein 0.0183 0.2228 0.2284
Echinococcus granulosus TGF beta signal transducer SmadC 0.0011 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0022 0.016 0.0717
Echinococcus granulosus para nitrobenzyl esterase 0.0084 0.0951 0.0981
Treponema pallidum NADH oxidase 0.0034 0.0312 0.0983
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0025 0.0199 0.0199
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0054 0.0575 0.0575
Mycobacterium tuberculosis Conserved protein 0.0011 0.0024 0.0039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0088 0.1002 0.1002
Echinococcus granulosus tm gpcr rhodopsin 0.0314 0.3907 0.4033
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0014 0.0056 0.0253
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0171 0.2068 0.2068
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0069 0.0763 0.0788
Onchocerca volvulus 0.0088 0.1002 0.1012
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0253 0.0261
Schistosoma mansoni cpg binding protein 0.003 0.0258 0.0266
Echinococcus multilocularis apoptotic protease activating factor 1 0.0026 0.0208 0.0208
Schistosoma mansoni tar DNA-binding protein 0.0028 0.024 0.0248
Loa Loa (eye worm) hypothetical protein 0.0084 0.0951 0.0975
Brugia malayi Calcitonin receptor-like protein seb-1 0.054 0.6802 0.7015
Echinococcus multilocularis isocitrate dehydrogenase 0.0069 0.0763 0.0763
Trichomonas vaginalis aldo-keto reductase, putative 0.0076 0.0853 0.088
Loa Loa (eye worm) thioredoxin reductase 0.0098 0.1132 0.1163
Echinococcus multilocularis BC026374 protein (S09 family) 0.0084 0.0951 0.0951
Onchocerca volvulus 0.0084 0.0951 0.0958
Brugia malayi glutaminase DH11.1 0.061 0.7701 0.7945
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.019 0.019
Onchocerca volvulus 0.0076 0.0853 0.0857
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.0303
Schistosoma mansoni alpha-1 adrenergic receptor 0.0088 0.1002 0.1034
Leishmania major importin beta-1 subunit, putative 0.0028 0.0237 0.0242
Echinococcus granulosus neuropeptide Y receptor 0.0088 0.1002 0.1034
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0054 0.0575 0.0575
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0088 0.1002 0.1034
Loa Loa (eye worm) oxidoreductase 0.0076 0.0853 0.0874
Trypanosoma brucei polo-like protein kinase 0.0765 0.9688 1
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0088 0.1002 0.1002
Schistosoma mansoni hypothetical protein 0.0161 0.1946 0.2009
Echinococcus granulosus fmrfamide receptor 0.0088 0.1002 0.1034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0054 0.0575 0.0594
Echinococcus granulosus neuropeptides capa receptor 0.0088 0.1002 0.1034
Echinococcus granulosus aldehyde reductase 0.0054 0.057 0.0588
Onchocerca volvulus 0.0043 0.0433 0.0423
Loa Loa (eye worm) hypothetical protein 0.0088 0.1002 0.1028
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0312 0.0303
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.004 0.0385 0.0385
Echinococcus granulosus tachykinin peptides receptor 99D 0.0088 0.1002 0.1034
Onchocerca volvulus 0.007 0.078 0.0782
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0018 0.0103 0.0331
Plasmodium vivax ataxin-2 like protein, putative 0.0183 0.2228 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0223 0.274 0.8955
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.078 0.078
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0098 0.1132 0.2002
Onchocerca volvulus 0.0088 0.1002 0.1012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0024 0.0039
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0248 0.306 0.5416
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0011 0.0024 0.0025
Brugia malayi Importin beta-1 subunit 0.0035 0.032 0.0311
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.0428
Schistosoma mansoni serine/threonine protein kinase 0.0765 0.9688 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0314 0.3907 0.3907
Brugia malayi hypothetical protein 0.0088 0.1002 0.1016
Brugia malayi DIX domain containing protein 0.0012 0.0029 0.001
Schistosoma mansoni hypothetical protein 0.04 0.5004 0.5165
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Echinococcus granulosus glycine receptor subunit alpha 1 0.0054 0.0575 0.0594
Loa Loa (eye worm) hypothetical protein 0.0096 0.1106 0.1136
Trypanosoma brucei protein kinase A regulatory subunit 0.0011 0.0024 0.0023
Plasmodium falciparum thioredoxin reductase 0.0098 0.1132 0.5082
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0054 0.0575 0.0594
Leishmania major C-8 sterol isomerase-like protein 0.0307 0.3821 0.3942
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0433 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0433 0.1946
Brugia malayi Carboxylesterase family protein 0.0084 0.0951 0.0963
Trichomonas vaginalis CAMK family protein kinase 0.0765 0.9688 1
Schistosoma mansoni importin beta-1 0.0035 0.032 0.0331
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0105 0.1218 0.1218
Mycobacterium tuberculosis Carboxylesterase LipT 0.0084 0.0951 0.168
Plasmodium vivax metacaspase 1, putative 0.0011 0.0019 0.0087
Loa Loa (eye worm) hypothetical protein 0.0025 0.0199 0.0199
Toxoplasma gondii type I fatty acid synthase, putative 0.0016 0.0077 0.0347
Toxoplasma gondii thioredoxin reductase 0.0098 0.1132 0.5082
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0082 0.0931 0.0931
Loa Loa (eye worm) hypothetical protein 0.008 0.0902 0.0925
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1131 0.1168
Loa Loa (eye worm) glutathione reductase 0.0098 0.1132 0.1163
Echinococcus granulosus 7TM GPCR rhodopsin 0.0088 0.1002 0.1034
Loa Loa (eye worm) mbt repeat family protein 0.0027 0.0217 0.0218
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0043 0.0044
Mycobacterium ulcerans hypothetical protein 0.0011 0.0024 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0312 0.0303
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0022 0.016 0.0145
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.004 0.0393 0.0387
Schistosoma mansoni hypothetical protein 0.0171 0.2068 0.2135
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0054 0.0575 0.0575
Echinococcus granulosus snurportin 1 0.0369 0.461 0.4759
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0011 0.0019 0.002
Plasmodium vivax hypothetical protein, conserved 0.007 0.078 0.3502
Brugia malayi GnHR receptor homolog 0.0088 0.1002 0.1016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.1002 0.1002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.