Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.2804 | 0.2429 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0495 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0495 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0495 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.2547 | 0.2159 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0495 | 0.5 |
Brugia malayi | RNA binding protein | 0.007 | 0.2804 | 0.2804 |
Brugia malayi | TAR-binding protein | 0.007 | 0.2804 | 0.2804 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.2804 | 0.2804 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.2547 | 0.2547 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0495 | 0.0495 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0495 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.2547 | 0.2547 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0206 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2804 | 0.0641 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0495 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.2804 | 0.2429 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.2804 | 0.2429 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2804 | 0.0641 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0495 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.2804 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0495 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0206 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.2804 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.2547 | 0.2159 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0141 | 0.655 | 0.655 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0206 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2804 | 0.0641 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2804 | 0.0641 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.2804 | 0.0641 |
Schistosoma mansoni | hypothetical protein | 0.0141 | 0.655 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.655 | 0.6371 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.