Detailed information for compound 655168

Basic information

Technical information
  • TDR Targets ID: 655168
  • Name: 6-bromo-3-[4-(4-ethoxyphenyl)-1,3-thiazol-2-y l]chromen-2-one
  • MW: 428.299 | Formula: C20H14BrNO3S
  • H donors: 0 H acceptors: 2 LogP: 5.3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)c1csc(n1)c1cc2cc(Br)ccc2oc1=O
  • InChi: 1S/C20H14BrNO3S/c1-2-24-15-6-3-12(4-7-15)17-11-26-19(22-17)16-10-13-9-14(21)5-8-18(13)25-20(16)23/h3-11H,2H2,1H3
  • InChiKey: ICERQQFTBLETRC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 6-bromo-3-[4-(4-ethoxyphenyl)thiazol-2-yl]chromen-2-one
  • 6-bromo-3-[4-(4-ethoxyphenyl)-2-thiazolyl]-2-chromenone
  • 6-bromo-3-[4-(4-ethoxyphenyl)thiazol-2-yl]coumarin
  • ChemDiv1_000372
  • EU-0068052
  • STOCK1S-26662

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0124 0.1599
Trypanosoma brucei DNA repair protein, putative 0.0009 0.0002 0.0095
Loa Loa (eye worm) hypothetical protein 0.0047 0.0171 0.0171
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.0164 0.0659
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0015 0.0027 0.0094
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Schistosoma mansoni rab6-interacting 0.0018 0.0041 0.0142
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) cytochrome P450 0.0014 0.0025 0.0025
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0124 0.0511 0.0511
Entamoeba histolytica hypothetical protein 0.0028 0.0088 0.2182
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0124 0.0511 0.1775
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0332 0.1429 0.4968
Plasmodium vivax glutathione reductase, putative 0.0052 0.0191 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0311 0.1333 0.4634
Brugia malayi acetyltransferase, GNAT family protein 0.0082 0.0326 0.1311
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.0164 0.0569
Echinococcus granulosus orexin receptor type 2 0.0046 0.0164 0.0569
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.0164 0.0569
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.0021 0.0074
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0042 0.2203
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Brugia malayi hypothetical protein 0.0057 0.0216 0.0868
Echinococcus granulosus Regulator of G protein signaling 20 0.001 0.0007 0.0026
Echinococcus multilocularis lysine specific demethylase 5A 0.0031 0.0099 0.0345
Loa Loa (eye worm) calcium channel 0.0048 0.0176 0.0176
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0181 0.0629
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0037 0.0126 0.6599
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0042 0.0086
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0079 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Treponema pallidum hypothetical protein 0.0016 0.0035 0.0331
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0164 0.0569
Echinococcus granulosus lamin 0.0011 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0124 0.0511 0.1775
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0181 0.0629
Plasmodium vivax SET domain protein, putative 0.0047 0.0171 0.8755
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0011 0.0009 0.0038
Echinococcus multilocularis lysosomal alpha glucosidase 0.0064 0.0246 0.0856
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.001 0.0007 0.0026
Echinococcus granulosus glycine receptor subunit alpha 1 0.0124 0.0511 0.1775
Echinococcus multilocularis carboxylesterase 5A 0.0572 0.2486 0.8641
Loa Loa (eye worm) hypothetical protein 0.0311 0.1333 0.1333
Loa Loa (eye worm) acetylcholinesterase 1 0.0572 0.2486 0.2486
Plasmodium falciparum potassium channel 0.0028 0.0088 0.3145
Onchocerca volvulus Serine\/threonine kinase homolog 0.0038 0.0129 0.0788
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0125 0.6524
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0028 0.0088 0.0088
Echinococcus granulosus histone acetyltransferase KAT2B 0.008 0.0316 0.1097
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0048 0.0176 0.0611
Brugia malayi Carboxylesterase family protein 0.0097 0.0389 0.1566
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Echinococcus granulosus poly adp ribose polymerase 2 0.0037 0.0126 0.0439
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0216 0.0868
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0171 0.0594
Brugia malayi follicle stimulating hormone receptor 0.03 0.1286 0.5173
Echinococcus granulosus muscleblind protein 0.0146 0.0607 0.211
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0124 0.0511 0.0511
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0037 0.0126 0.0439
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0067 0.026 0.0904
Schistosoma mansoni acetylcholine receptor-related 0.0057 0.0216 0.075
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0014 0.0025 0.0647
Echinococcus granulosus glycine receptor subunit beta 0.0124 0.0511 0.1775
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0332 0.1429 0.4968
Brugia malayi ORL1-like opioid receptor 0.0046 0.0164 0.0659
Schistosoma mansoni opsin-like receptor 0.0046 0.0164 0.0569
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0021 0.0085
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0124 0.0511 0.2054
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0572 0.2486 0.8641
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0024 0.007 0.1807
Brugia malayi intermediate filament protein 0.0011 0.0013 0.0053
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0014 0.0025 0.0326
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.0511 0.2054
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0024 0.007 0.0433
Entamoeba histolytica hypothetical protein 0.001 0.0007 0.0184
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Onchocerca volvulus 0.0124 0.0511 0.3161
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0015 0.0027 0.0351
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0036 0.0124 0.6463
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Schistosoma mansoni hypothetical protein 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Brugia malayi Carboxylesterase family protein 0.0097 0.0389 0.1566
Schistosoma mansoni axis inhibition protein axin 0.001 0.0007 0.0026
Brugia malayi Carboxylesterase family protein 0.0572 0.2486 1
Loa Loa (eye worm) acetyltransferase 0.0082 0.0326 0.0326
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0028 0.0088 0.0088
Trypanosoma brucei glucosidase, putative 0.0014 0.0026 0.1353
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.003 0.0094 0.1214
Brugia malayi serine/threonine-protein kinase plk-2 0.0038 0.0129 0.0518
Onchocerca volvulus 0.0057 0.0216 0.1328
Toxoplasma gondii hypothetical protein 0.0021 0.0055 0.1206
Loa Loa (eye worm) uncoordinated protein 58 0.0028 0.0088 0.0088
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0093 0.0373 0.9567
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0026 0.0161
Leishmania major calcium/potassium channel (CAKC), putative 0.0028 0.0088 0.4609
Onchocerca volvulus 0.0018 0.0041 0.0242
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0216 0.0868
Trichomonas vaginalis D-aminoacylase, putative 0.0015 0.0027 0.0168
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0042 0.2203
Echinococcus granulosus axis inhibition protein axin 0.001 0.0007 0.0026
Echinococcus multilocularis nAChR subunit 0.0067 0.0258 0.0897
Trichomonas vaginalis set domain proteins, putative 0.0374 0.1612 1
Brugia malayi G-protein coupled receptor 0.0046 0.0164 0.0659
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0124 0.0511 0.1775
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0014 0.0025 0.0647
Onchocerca volvulus 0.0047 0.0171 0.105
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0028 0.0088 0.4609
Loa Loa (eye worm) TWK-7 protein 0.0028 0.0088 0.0088
Onchocerca volvulus 0.0015 0.0027 0.0157
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus multilocularis muscleblind protein 0.0146 0.0607 0.211
Schistosoma mansoni BC026374 protein (S09 family) 0.0097 0.0389 0.1353
Onchocerca volvulus 0.0311 0.1333 0.8268
Schistosoma mansoni rab6-interacting 0.0018 0.0041 0.0142
Brugia malayi Cytochrome P450 family protein 0.0027 0.0083 0.0333
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Mycobacterium ulcerans esterase/lipase LipP 0.0015 0.0027 0.0351
Onchocerca volvulus 0.0122 0.0501 0.31
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.0164 0.0164
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Brugia malayi Pre-SET motif family protein 0.0047 0.0171 0.0687
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0125 0.404
Schistosoma mansoni amine GPCR 0.0046 0.0164 0.0569
Echinococcus multilocularis serotonin receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.0161
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.0161
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.0161
Leishmania major potassium channel subunit-like protein 0.0028 0.0088 0.4609
Brugia malayi hypothetical protein 0.0018 0.0041 0.0164
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0124 0.3174
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0028 0.0088 0.0355
Brugia malayi hypothetical protein 0.001 0.0007 0.003
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0071 0.1839
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.0164 0.0569
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0047 0.0171 0.2213
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.0164 0.0569
Echinococcus granulosus g protein coupled receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.001 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0661 0.2877 0.2877
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0066 0.0253 0.0879
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0019 0.0047 0.0612
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0014 0.0025 0.0647
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0124 0.1599
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0045 0.0163 0.0567
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0057 0.0216 0.075
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0164 0.0164
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Onchocerca volvulus 0.0046 0.0164 0.1006
Echinococcus multilocularis lysosomal alpha glucosidase 0.0064 0.0246 0.0856
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.0161
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.0511 0.2054
Trichomonas vaginalis aldehyde oxidase, putative 0.01 0.0404 0.2507
Trypanosoma brucei calcium-activated potassium channel, putative 0.0028 0.0088 0.4609
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0014 0.0025 0.0326
Schistosoma mansoni gliotactin 0.0097 0.0389 0.1353
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0028 0.0088 0.4609
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0014 0.0025 0.0647
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0026 0.1353
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0258 0.1038
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0014 0.0025 0.0647
Loa Loa (eye worm) carboxylesterase 0.0097 0.0389 0.0389
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0047 0.0171 0.5909
Entamoeba histolytica hypothetical protein 0.001 0.0009 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0046
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0028 0.0088 0.0355
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0014 0.0025 0.0326
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0125 0.3087
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) LGC-31 protein 0.0124 0.0511 0.0511
Echinococcus granulosus Polycystic kidney disease protein 0.0018 0.0041 0.0142
Onchocerca volvulus 0.0067 0.0258 0.1592
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0048 0.0176 0.0611
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Loa Loa (eye worm) hypothetical protein 0.0146 0.0607 0.0607
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0181 0.0181
Mycobacterium tuberculosis Probable dehydrogenase 0.0059 0.0224 0.5745
Echinococcus multilocularis potassium channel subfamily K 0.0028 0.0088 0.0306
Echinococcus multilocularis microtubule associated protein 2 0.0531 0.2304 0.8006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0042 0.2203
Loa Loa (eye worm) hypothetical protein 0.0146 0.0607 0.0607
Echinococcus multilocularis musashi 0.0011 0.0013 0.0046
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0164 0.0569
Loa Loa (eye worm) thioredoxin reductase 0.0052 0.0191 0.0191
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0072 0.0282 0.7237
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis calcium activated potassium channel variant 0.0028 0.0088 0.0306
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Schistosoma mansoni amine GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Mycobacterium tuberculosis Carboxylesterase LipT 0.0097 0.0389 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0171 0.0594
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.01 0.0404 1
Brugia malayi hypothetical protein 0.0064 0.0245 0.0985
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0014 0.0026 0.0026
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0332 0.1429 0.5749
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0028 0.0088 0.0355
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0171 0.0594
Plasmodium vivax potassium channel, putative 0.0028 0.0088 0.3717
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0034 0.0112 0.1449
Leishmania major hypothetical protein, conserved 0.0011 0.0013 0.0658
Schistosoma mansoni biogenic amine receptor 0.0046 0.0164 0.0569
Schistosoma mansoni polycystin 1-related 0.0018 0.0041 0.0142
Onchocerca volvulus 0.0046 0.0164 0.1006
Schistosoma mansoni nAChR subunit 0.0057 0.0216 0.075
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0057 0.0216 0.0868
Echinococcus multilocularis nAChR subunit 0.0124 0.0511 0.1775
Onchocerca volvulus 0.0046 0.0164 0.1006
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0044 0.0155 0.3991
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus neuropeptide receptor A26 0.0046 0.0164 0.0569
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0046
Leishmania major hypothetical protein, conserved 0.0028 0.0088 0.4609
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0036 0.0124 0.043
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0014 0.0025 0.0326
Schistosoma mansoni hypothetical protein 0.0018 0.0041 0.0142
Echinococcus multilocularis neuropeptide receptor A26 0.0046 0.0164 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0014 0.0025 0.0647
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Giardia lamblia Histone acetyltransferase GCN5 0.0022 0.0061 0.1505
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis axis inhibition protein axin 0.001 0.0007 0.0026
Echinococcus granulosus twik family of potassium channels 0.0028 0.0088 0.0306
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.0164 0.0659
Echinococcus multilocularis voltage dependent calcium channel 0.0048 0.0176 0.0611
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0014 0.0025 0.0326
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0124 0.0511 0.1775
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Onchocerca volvulus 0.0374 0.1612 1
Trypanosoma brucei poly(adp-ribose) polymerase 0.0037 0.0126 0.6599
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Echinococcus granulosus thioredoxin glutathione reductase 0.0052 0.0191 0.0665
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.0164 0.0569
Plasmodium vivax potassium channel, putative 0.0028 0.0088 0.3717
Echinococcus multilocularis Regulator of G protein signaling 20 0.001 0.0007 0.0026
Onchocerca volvulus 0.0015 0.0027 0.0157
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0007 0.0026
Loa Loa (eye worm) ACC-1 protein 0.0124 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0072 0.0282 0.7237
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0011 0.0013 0.0013
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0083 0.0083
Leishmania major cytochrome p450-like protein 0.0014 0.0025 0.1318
Mycobacterium ulcerans beta-lactamase 0.0015 0.0027 0.0351
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Echinococcus granulosus poly (ADP ribose) polymerase 0.001 0.0009 0.0032
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0124 0.0511 0.1775
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0034 0.0112 0.1449
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0042 0.2203
Echinococcus multilocularis thioredoxin glutathione reductase 0.0052 0.0191 0.0665
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0046
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.0164 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0014 0.0025 0.0647
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0028 0.0088 0.0355
Echinococcus multilocularis glycine receptor subunit beta 0.0124 0.0511 0.1775
Echinococcus granulosus somatostatin receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) glutathione reductase 0.0052 0.0191 0.0191
Echinococcus granulosus poly (ADP ribose) polymerase 0.001 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0059 0.0224 0.7736
Leishmania major hypothetical protein, conserved 0.0015 0.0027 0.1418
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0332 0.1429 0.4968
Brugia malayi hypothetical protein 0.0057 0.0216 0.0868
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0028 0.0088 0.0355
Onchocerca volvulus 0.0046 0.0164 0.1006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.0164 0.0569
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Onchocerca volvulus 0.0015 0.0027 0.0157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.0511 0.2054
Echinococcus granulosus WGR domain containing protein 0.0021 0.0055 0.0192
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0124 0.0511 0.2054
Schistosoma mansoni myosin xvIII 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0015 0.0031 0.0108
Schistosoma mansoni lipoxygenase 0.0034 0.0113 0.0392
Loa Loa (eye worm) hypothetical protein 0.0037 0.0126 0.0126
Loa Loa (eye worm) inositol-1 0.0037 0.0125 0.0125
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0013 0.0021 0.0085
Loa Loa (eye worm) hypothetical protein 0.0253 0.1081 0.1081
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0125 0.1615
Echinococcus granulosus glycine receptor subunit beta 0.0124 0.0511 0.1775
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0026 0.1353
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0094 0.0584
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0019 0.0047 0.1214
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Onchocerca volvulus 0.0046 0.0164 0.1006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.0511 0.2054
Brugia malayi Serotonin receptor 0.0046 0.0164 0.0659
Schistosoma mansoni inositol monophosphatase 0.0037 0.0125 0.0434
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0048 0.0176 0.0611
Trichomonas vaginalis penicillin-binding protein, putative 0.0015 0.0027 0.0168
Schistosoma mansoni neurotransmitter gated ion channel 0.0057 0.0216 0.075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Onchocerca volvulus 0.0046 0.0164 0.1006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0171 0.0719 0.2499
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.0161
Onchocerca volvulus 0.0046 0.0164 0.1006
Onchocerca volvulus 0.0037 0.0127 0.0777
Plasmodium falciparum histone acetyltransferase GCN5 0.0022 0.0061 0.1331
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0125 0.0774
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0025 0.1318
Loa Loa (eye worm) carboxylesterase 0.0097 0.0389 0.0389
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0097 0.0389 0.1353
Brugia malayi Carboxylesterase family protein 0.0097 0.0389 0.1566
Schistosoma mansoni acetylcholinesterase 0.0097 0.0389 0.1353
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis esterase, putative 0.0015 0.0027 0.0168
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.0071 0.0245
Schistosoma mansoni calcium-activated potassium channel 0.0553 0.2404 0.8356
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0171 0.0594
Brugia malayi Serotonin receptor 0.0046 0.0164 0.0659
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0014 0.0025 0.0326
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Echinococcus granulosus potassium channel subfamily K 0.0028 0.0088 0.0306
Brugia malayi neuropeptide F receptor 0.0046 0.0164 0.0659
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0036 0.0124 0.6463
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0014 0.0025 0.0647
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0125 0.0774
Schistosoma mansoni multidrug resistance protein 0.0011 0.0013 0.0044
Schistosoma mansoni microtubule-associated protein tau 0.0531 0.2304 0.8006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0097 0.0389 0.1353
Schistosoma mansoni hypothetical protein 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.0042 0.0545
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0088 0.4609
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0014 0.0025 0.0326
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Brugia malayi AKH receptor 0.0046 0.0164 0.0659
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0014 0.0025 0.0326
Echinococcus granulosus g protein coupled receptor 0.0046 0.0164 0.0569
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0055
Plasmodium vivax multidomain scavenger receptor, putative 0.0018 0.0041 0.0835
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0059 0.0224 0.5745
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0658
Mycobacterium tuberculosis Probable lipase LipE 0.0015 0.0027 0.0697
Brugia malayi Cytochrome P450 family protein 0.0014 0.0025 0.0101
Echinococcus granulosus regulator of G protein signaling 3 0.001 0.0007 0.0026
Echinococcus multilocularis sex peptide receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.0164 0.0164
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0026 0.064
Schistosoma mansoni voltage-gated cation channel 0.0048 0.0176 0.0611
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Trypanosoma brucei polo-like protein kinase 0.0038 0.0129 0.6732
Trichomonas vaginalis spcc417.12 protein, putative 0.0097 0.0389 0.2415
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0014 0.0025 0.0326
Onchocerca volvulus 0.0028 0.0088 0.0536
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Schistosoma mansoni acetylcholine receptor subunit beta 0.0057 0.0216 0.075
Trichomonas vaginalis CAMK family protein kinase 0.0019 0.0046 0.0284
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0019 0.0047 0.0612
Schistosoma mansoni cytochrome P450 0.0014 0.0025 0.0088
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.003 0.0094 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0041 0.0142
Loa Loa (eye worm) hypothetical protein 0.0011 0.0013 0.0013
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.0042 0.5
Echinococcus granulosus BC026374 protein S09 family 0.0097 0.0389 0.1353
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Onchocerca volvulus 0.0046 0.0164 0.1006
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0042 0.0086
Onchocerca volvulus 0.0097 0.0389 0.2407
Echinococcus multilocularis serotonin receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Echinococcus multilocularis neutral alpha glucosidase AB 0.0014 0.0026 0.009
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0083 0.4331
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0124 0.0511 0.0511
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0181 0.0728
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0028 0.0088 0.0355
Onchocerca volvulus 0.0046 0.0164 0.1006
Onchocerca volvulus 0.0124 0.0511 0.3161
Schistosoma mansoni neuropeptide receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis regulator of G protein signaling 3 0.001 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0042 0.0261
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0036 0.0124 0.043
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.0164 0.0659
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0044 0.0155 0.0964
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Brugia malayi putative neuropeptide receptor 0.0046 0.0164 0.0659
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0048 0.0176 0.0611
Echinococcus multilocularis regulator of G protein signaling 3 0.001 0.0007 0.0026
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0031 0.0099 0.0345
Brugia malayi Doublecortin family protein 0.0018 0.0041 0.0164
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0658
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0124 0.0511 0.1775
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0041 0.0142
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0097 0.0389 0.1353
Echinococcus multilocularis RUN 0.0018 0.0041 0.0142
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Onchocerca volvulus 0.0018 0.0041 0.0242
Trypanosoma brucei membrane transporter protein, putative 0.0011 0.0013 0.0658
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0332 0.1429 0.4968
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0042 0.0686
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.0164 0.0569
Giardia lamblia DNA repair protein RAD52 0.01 0.0403 0.9968
Plasmodium falciparum potassium channel 0.0028 0.0088 0.3145
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0028 0.0088 0.0355
Giardia lamblia Fructose-bisphosphate aldolase 0.01 0.0404 1
Echinococcus granulosus para nitrobenzyl esterase 0.0097 0.0389 0.1353
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0014 0.0025 0.0647
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.001 0.0007 0.0046
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0049 0.0179 0.5977
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0164 0.0569
Brugia malayi GnHR receptor homolog 0.0046 0.0164 0.0659
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0027 0.1418
Schistosoma mansoni opsin-like receptor 0.0046 0.0164 0.0569
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.01 0.0403 0.9968
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0097 0.0389 0.1353
Plasmodium falciparum thioredoxin reductase 0.0018 0.0042 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0181 0.0629
Schistosoma mansoni biogenic amine receptor 0.0046 0.0164 0.0569
Brugia malayi Dopamine receptor protein 2 0.0046 0.0164 0.0659
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0028 0.0088 0.0355
Echinococcus multilocularis somatostatin receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis 0.0014 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0009 0.0033
Schistosoma mansoni jumonji domain containing protein 0.0031 0.0099 0.0345
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.0021 0.0074
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0057 0.0216 0.0216
Echinococcus granulosus fmrfamide receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Echinococcus multilocularis twik family of potassium channels 0.0028 0.0088 0.0306
Schistosoma mansoni neurotransmitter gated ion channel 0.0067 0.0258 0.0897
Echinococcus granulosus poly (ADP ribose) polymerase 0.0021 0.0055 0.0192
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0014 0.0025 0.0326
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0164 0.0164
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0021 0.0085
Loa Loa (eye worm) hypothetical protein 0.0292 0.125 0.125
Loa Loa (eye worm) PXA domain-containing protein 0.001 0.0007 0.0007
Brugia malayi regulator of G-protein signaling rgs-7 0.001 0.0007 0.003
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0037 0.0126 0.0439
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0036 0.0124 0.6461
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0038 0.0129 0.0448
Brugia malayi hypothetical protein 0.0057 0.0216 0.0868
Loa Loa (eye worm) hypothetical protein 0.0262 0.1118 0.1118
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0124 0.0511 0.0511
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0332 0.1429 0.4968
Onchocerca volvulus 0.0097 0.0389 0.2407
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Mycobacterium tuberculosis Probable reductase 0.0059 0.0224 0.5745
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0064 0.0246 0.0246
Treponema pallidum quinoline 2-oxidoreductase 0.0016 0.0033 0.0287
Schistosoma mansoni regulator of G protein signaling 0.001 0.0007 0.0026
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0099 0.0345
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0311 0.1333 0.1333
Echinococcus multilocularis glycine receptor subunit beta 0.0124 0.0511 0.1775
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0015 0.0027 0.0697
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0027 0.1418
Loa Loa (eye worm) hypothetical protein 0.0024 0.0071 0.0071
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0057 0.0216 0.0868
Toxoplasma gondii ABC1 family protein 0.0015 0.0027 0.0078
Brugia malayi hypothetical protein 0.0028 0.0088 0.0355
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0024 0.007 0.2596
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0007 0.003
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0025 0.1318
Trypanosoma cruzi polo-like protein kinase, putative 0.0038 0.0129 0.6732
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0027 0.008 0.008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.0511 0.2054
Schistosoma mansoni hypothetical protein 0.0014 0.0025 0.0088
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0066 0.0255 0.3303
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0049 0.0179 0.2311
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0014 0.0025 0.0326
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0057 0.0216 0.075
Onchocerca volvulus Putative nachr subunit 0.0332 0.1429 0.8866
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0014 0.0025 0.0647
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0032 0.0104 0.0362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.0164 0.0164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Brugia malayi A-kinase anchor protein 10, precursor 0.001 0.0007 0.003
Brugia malayi hypothetical protein 0.001 0.0007 0.003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0025 0.1318
Echinococcus multilocularis acetylcholinesterase 0.0572 0.2486 0.8641
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis penicillin-binding protein, putative 0.0015 0.0027 0.0168
Brugia malayi Cytochrome P450 family protein 0.0027 0.0083 0.0333
Echinococcus granulosus glycine receptor subunit alpha 1 0.0124 0.0511 0.1775
Mycobacterium tuberculosis Conserved protein 0.0015 0.0027 0.0697
Echinococcus multilocularis para nitrobenzyl esterase 0.0097 0.0389 0.1353
Onchocerca volvulus 0.0046 0.0164 0.1006
Echinococcus multilocularis BC026374 protein (S09 family) 0.0097 0.0389 0.1353
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0046
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0164 0.0569
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0083 0.4331
Echinococcus multilocularis axis inhibition protein axin 0.001 0.0007 0.0026
Schistosoma mansoni kinase 0.0019 0.0048 0.0167
Schistosoma mansoni hypothetical protein 0.0046 0.0164 0.0569
Brugia malayi hypothetical protein 0.0057 0.0216 0.0868
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0042 0.0261
Leishmania major hypothetical protein, conserved 0.0028 0.0088 0.4609
Brugia malayi Dopamine receptor protein 1 0.0046 0.0164 0.0659
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.0164 0.0569
Schistosoma mansoni alpha glucosidase 0.0014 0.0026 0.009
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0181 0.0629
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0014 0.0025 0.0326
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.0164 0.0569
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Onchocerca volvulus 0.0046 0.0164 0.1006
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.001 0.0007 0.0026
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0042 0.2203
Schistosoma mansoni serine/threonine protein kinase 0.0011 0.0009 0.0033
Loa Loa (eye worm) glutaminase 0.0184 0.0773 0.0773
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.0164 0.0659
Schistosoma mansoni regulator of G protein signaling 0.001 0.0007 0.0026
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.0164 0.0569
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.0164 0.0569
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0042 0.0146
Echinococcus granulosus poly (ADP ribose) polymerase 0.001 0.0009 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Brugia malayi Cation transporter family protein 0.0124 0.0511 0.2054
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0124 0.0511 0.2054
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Brugia malayi hypothetical protein 0.0018 0.0041 0.0164
Onchocerca volvulus 0.0046 0.0164 0.1006
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0013 0.0021 0.0021
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0057 0.0216 0.0868
Brugia malayi G-protein coupled receptor 0.0046 0.0164 0.0659
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0125 0.6524
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0041 0.0142
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0028 0.0088 0.4609
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0088 0.4609
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0164 0.0164
Brugia malayi cytochrome P450 0.0014 0.0025 0.0101
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0083 0.1072
Schistosoma mansoni nAChR subunit 0.0057 0.0216 0.075
Mycobacterium tuberculosis Probable esterase LipL 0.0015 0.0027 0.0697
Trichomonas vaginalis bromodomain-containing protein, putative 0.0024 0.007 0.0433
Leishmania major hypothetical protein, conserved 0.0009 0.0002 0.0095
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0658
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.001 0.0007 0.0026
Onchocerca volvulus 0.0028 0.0088 0.0536
Brugia malayi beta-lactamase 0.0015 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Brugia malayi beta-lactamase family protein 0.0015 0.0027 0.0109
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0042 0.2203
Loa Loa (eye worm) ACC-1 protein 0.0124 0.0511 0.0511
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0191 1
Onchocerca volvulus 0.0046 0.0164 0.1006
Leishmania major ion transport protein-like protein 0.0028 0.0088 0.4609
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0018 0.0041 0.0041
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0066 0.0253 0.0879
Schistosoma mansoni neuropeptide receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0028 0.0088 0.0355
Schistosoma mansoni amine GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0014 0.0025 0.0326
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0025 0.1318
Echinococcus granulosus potassium channel subfamily K 8 0.0028 0.0088 0.0306
Loa Loa (eye worm) carboxylesterase 0.0572 0.2486 0.2486
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0067 0.0258 0.1038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0011 0.0013 0.0044
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0042 0.0146
Schistosoma mansoni lipoxygenase 0.0066 0.0253 0.0879
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Schistosoma mansoni calcium-activated potassium channel 0.0661 0.2877 1
Onchocerca volvulus 0.0046 0.0164 0.1006
Echinococcus granulosus serotonin receptor 0.0046 0.0164 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0014 0.0025 0.0647
Brugia malayi Pre-SET motif family protein 0.0329 0.1412 0.5679
Onchocerca volvulus 0.0097 0.0389 0.2407
Schistosoma mansoni neuroligin 3 (S09 family) 0.0097 0.0389 0.1353
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0014 0.0025 0.0647
Loa Loa (eye worm) hypothetical protein 0.0051 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0021 0.0055 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0015 0.0027 0.0168
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0131 0.0811
Echinococcus multilocularis acetylcholinesterase 0.0572 0.2486 0.8641
Brugia malayi excitatory GABA receptor EXP-1A 0.0124 0.0511 0.2054
Trichomonas vaginalis xanthine dehydrogenase, putative 0.01 0.0404 0.2507
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0329 0.1412 0.1412
Brugia malayi Muscleblind-like protein 0.0146 0.0607 0.2442
Onchocerca volvulus 0.0011 0.0013 0.0071
Loa Loa (eye worm) glutaminase 2 0.0184 0.0773 0.0773
Echinococcus granulosus twik family of potassium channels 0.0028 0.0088 0.0306
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0028 0.0088 0.2181
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Onchocerca volvulus 0.0097 0.0389 0.2407
Entamoeba histolytica acetyltransferase, GNAT family 0.0022 0.0061 0.1505
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0067 0.026 0.6433
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0042 0.0169
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0048 0.0176 0.0611
Echinococcus granulosus glycine receptor subunit alpha 1 0.0124 0.0511 0.1775
Echinococcus granulosus RUN 0.0018 0.0041 0.0142
Mycobacterium ulcerans lipase LipD 0.0015 0.0027 0.0351
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0028 0.0088 0.0306
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0059 0.0224 0.5745
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0044 0.0155 0.2011
Echinococcus granulosus geminin 0.0355 0.1528 0.531
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0014 0.0025 0.0326
Schistosoma mansoni regulator of G protein signaling 0.001 0.0007 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Schistosoma mansoni amine GPCR 0.0046 0.0164 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0014 0.0025 0.0647
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0125 0.0774
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Echinococcus multilocularis beta adrenergic receptor kinase 0.0011 0.0009 0.0033
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0057 0.0216 0.0868
Entamoeba histolytica hypothetical protein 0.0067 0.0258 0.6385
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Schistosoma mansoni regulator of G protein signaling 0.001 0.0007 0.0026
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0097 0.0389 0.2415
Brugia malayi PXA domain containing protein 0.001 0.0007 0.003
Echinococcus granulosus nAChR subunit 0.0124 0.0511 0.1775
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.0164 0.0569
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0026 0.064
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0164 0.0569
Entamoeba histolytica hypothetical protein 0.001 0.0007 0.0184
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0026 0.0161
Mycobacterium tuberculosis Conserved protein 0.0015 0.0027 0.0697
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0067 0.0258 0.1038
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.0042 0.0545
Onchocerca volvulus 0.0057 0.0216 0.1328
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0028 0.0088 0.0355
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.0164 0.0659
Echinococcus granulosus neutral alpha glucosidase AB 0.0014 0.0026 0.009
Loa Loa (eye worm) hypothetical protein 0.2276 1 1
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0028 0.0088 0.0306
Schistosoma mansoni regulator of G protein signaling 0.001 0.0007 0.0026
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.0164 0.0569
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0125 0.6524
Echinococcus multilocularis voltage dependent calcium channel 0.0048 0.0176 0.0611
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0046 0.0164 0.1006
Schistosoma mansoni alpha-glucosidase 0.0055 0.0207 0.0719
Onchocerca volvulus 0.0028 0.0088 0.0536
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.0042 0.1042
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.0164 0.0659
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Brugia malayi Melatonin receptor type 1A 0.0046 0.0164 0.0659
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0014 0.0025 0.0326
Leishmania major cytochrome p450-like protein 0.0027 0.0083 0.4331
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0259 0.1104 0.3837
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0124 0.0511 0.1775
Trypanosoma brucei MATE efflux family protein, putative 0.0011 0.0013 0.0658
Trichomonas vaginalis glutaminase, putative 0.0184 0.0773 0.4793
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.001 0.0007 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0014 0.0025 0.0647
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0042 0.2203
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0658
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0131 0.0811
Loa Loa (eye worm) hypothetical protein 0.0572 0.2486 0.2486
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0014 0.0025 0.0647
Loa Loa (eye worm) TWK-28 protein 0.0028 0.0088 0.0088
Echinococcus multilocularis neuropeptide s receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0038 0.0129 0.0799
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0258 0.1038
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0028 0.0088 0.0355
Brugia malayi neuropeptide F receptor 0.0046 0.0164 0.0659
Onchocerca volvulus 0.0028 0.0088 0.0536
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0036 0.0124 0.043
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0164 0.0569
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0124 0.0511 0.2054
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0052 0.0191 0.4912
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0124 0.0511 0.1775
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0028 0.0088 0.0355
Brugia malayi Cytochrome P450 family protein 0.0031 0.0099 0.04
Echinococcus granulosus regulator of G protein signaling 3 0.001 0.0007 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0028 0.0088 0.0355
Treponema pallidum NADH oxidase 0.0018 0.0042 0.0524
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Treponema pallidum fructose-bisphosphate aldolase 0.01 0.0404 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0026 0.0161
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0097 0.0389 0.1353
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0014 0.0025 0.0326
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0258 0.0897
Entamoeba histolytica serine/threonine protein kinase, putative 0.0038 0.0129 0.3185
Loa Loa (eye worm) doublecortin family protein 0.0018 0.0041 0.0041
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0014 0.0025 0.0647
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Trypanosoma brucei trypanothione reductase 0.0052 0.0191 1
Schistosoma mansoni intermediate filament proteins 0.0011 0.0013 0.0046
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0028 0.0088 0.0355
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0124 0.0511 0.2054
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0311 0.1333 0.4634
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0124 0.0511 0.1775
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0124 0.0511 0.2054
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.001 0.0008 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Echinococcus granulosus potassium channel subfamily K 8 0.0028 0.0088 0.0306
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0007 0.0007
Onchocerca volvulus 0.0028 0.0088 0.0536
Echinococcus granulosus acetylcholinesterase 0.0572 0.2486 0.8641
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0009 0.0002 0.0095
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0007 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0124 0.0511 0.2054
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Brugia malayi PXA domain containing protein 0.001 0.0007 0.003
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0031 0.0099 0.0345
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0124 0.0511 0.1775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Brugia malayi Intermediate filament tail domain containing protein 0.0011 0.0013 0.0053
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0124 0.0511 0.2054
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0026 0.0104
Echinococcus granulosus beta LACTamase domain containing family member 0.0015 0.0027 0.0094
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0041 0.0142
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0164 0.0569
Loa Loa (eye worm) follicle stimulating hormone receptor 0.03 0.1286 0.1286
Schistosoma mansoni hypothetical protein 0.0028 0.0088 0.0306
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0044 0.0155 0.5074
Echinococcus granulosus neuropeptide s receptor 0.0046 0.0164 0.0569
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0007 0.0046
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis potassium channel subfamily K 8 0.0028 0.0088 0.0306
Loa Loa (eye worm) hypothetical protein 0.0167 0.0698 0.0698
Loa Loa (eye worm) jmjC domain-containing protein 0.0031 0.0099 0.0099
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0011 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0355 0.1528 0.531
Loa Loa (eye worm) intermediate filament protein 0.0011 0.0013 0.0013
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0024 0.007 0.1807
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0083 0.4331
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.0164 0.0659
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0038 0.0129 0.0129
Schistosoma mansoni calcium-activated potassium channel 0.0028 0.0088 0.0306
Echinococcus multilocularis neuroligin 0.0097 0.0389 0.1353
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Loa Loa (eye worm) hypothetical protein 0.0572 0.2486 0.2486
Loa Loa (eye worm) hypothetical protein 0.0048 0.0176 0.0176
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0181 0.0629
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Schistosoma mansoni biogenic amine receptor 0.0046 0.0164 0.0569
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.0042 0.0545
Echinococcus multilocularis expressed protein 0.0196 0.0827 0.2875
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.0719 0.2499
Echinococcus granulosus microtubule associated protein 2 0.0531 0.2304 0.8006
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0015 0.0027 0.0697
Schistosoma mansoni neurotransmitter gated ion channel 0.0057 0.0216 0.075
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0125 0.0434
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.0164 0.0569
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0332 0.1429 0.1429
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0028 0.0088 0.4609
Echinococcus granulosus neuropeptide receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0083 0.0083
Brugia malayi Inositol-1 0.0037 0.0125 0.0502
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Echinococcus granulosus expressed protein 0.0196 0.0827 0.2875
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0124 0.0511 0.1775
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0048 0.0176 0.0611
Onchocerca volvulus 0.0046 0.0164 0.1006
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0007 0.0026
Echinococcus granulosus lysine specific demethylase 5A 0.0031 0.0099 0.0345
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0014 0.0025 0.0326
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0164 0.0569
Echinococcus multilocularis small conductance calcium activated potassium 0.0661 0.2877 1
Mycobacterium ulcerans transmembrane cation transporter 0.0028 0.0088 0.1141
Brugia malayi Regulator of G protein signaling domain containing protein 0.001 0.0007 0.003
Echinococcus granulosus small conductance calcium activated potassium 0.0661 0.2877 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0015
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0164 0.0569
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Giardia lamblia Hypothetical protein 0.0028 0.0088 0.2181
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis lamin dm0 0.0011 0.0013 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0014 0.0025 0.0647
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0164 0.0569
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Leishmania major cytochrome p450-like protein 0.0014 0.0025 0.1318
Echinococcus multilocularis orexin receptor type 2 0.0046 0.0164 0.0569
Brugia malayi hypothetical protein 0.0028 0.0088 0.0355
Echinococcus granulosus carboxylesterase 5A 0.0572 0.2486 0.8641
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.0164 0.0569
Mycobacterium ulcerans glutaminase 0.0184 0.0773 1
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.007 0.0272 1
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0025 0.0088
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0057 0.0216 0.0216
Onchocerca volvulus 0.0011 0.0013 0.0071
Onchocerca volvulus 0.0311 0.1333 0.8268
Brugia malayi hypothetical protein 0.0057 0.0216 0.0868
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0014 0.0025 0.0647
Brugia malayi glutaminase DH11.1 0.0184 0.0773 0.3108
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0028 0.0088 0.0306
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0332 0.1429 0.4968
Mycobacterium ulcerans carboxylesterase, LipT 0.0097 0.0389 0.504
Schistosoma mansoni hypothetical protein 0.0661 0.2877 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus granulosus g-protein coupled receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Mycobacterium tuberculosis Conserved protein 0.0015 0.0027 0.0697
Schistosoma mansoni amine GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.0164 0.0164
Brugia malayi G protein-coupled receptor 0.0046 0.0164 0.0659
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.0164 0.0569
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0048 0.0176 0.0611
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0082 0.0326 0.1133
Plasmodium falciparum thioredoxin reductase 0.0052 0.0191 1
Echinococcus granulosus calcium activated potassium channel variant 0.0028 0.0088 0.0306
Trypanosoma brucei membrane transporter protein, putative 0.0011 0.0013 0.0658
Echinococcus granulosus allatostatin A receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.0164 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0014 0.0025 0.0647
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Brugia malayi jmjC domain containing protein 0.0031 0.0099 0.0399
Echinococcus multilocularis twik family of potassium channels 0.0028 0.0088 0.0306
Schistosoma mansoni glutaminase 0.0184 0.0773 0.2685
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0171 0.0594
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0013 0.0658
Echinococcus granulosus neuroligin 0.0097 0.0389 0.1353
Schistosoma mansoni biogenic amine (5HT) receptor 0.0259 0.1104 0.3837
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0042 0.0914
Onchocerca volvulus 0.0046 0.0164 0.1006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0108 0.2769
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0057 0.0216 0.075
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus histone acetyltransferase KAT2B 0.0024 0.007 0.0242
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Brugia malayi WGR domain containing protein 0.0067 0.026 0.1046
Schistosoma mansoni calcium-activated potassium channel 0.0028 0.0088 0.0306
Brugia malayi Carboxylesterase family protein 0.0572 0.2486 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0015 0.0027 0.0027
Brugia malayi glutathione reductase 0.0052 0.0191 0.0769
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0034 0.0112 0.2875
Onchocerca volvulus 0.0046 0.0164 0.1006
Leishmania major alpha glucosidase II subunit, putative 0.0014 0.0026 0.1353
Echinococcus multilocularis regulator of G protein signaling 0.001 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus granulosus beta-adrenergic receptor kinase 0.0011 0.0009 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0057 0.0216 0.075
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0015 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0027
Trypanosoma cruzi DNA repair protein, putative 0.0009 0.0002 0.0095
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0015 0.0027 0.0094
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0037 0.0126 0.6599
Brugia malayi Thioredoxin reductase 0.0052 0.0191 0.0769
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0164 0.0569
Schistosoma mansoni adenoreceptor 0.0046 0.0164 0.0569
Echinococcus multilocularis potassium channel subfamily K 8 0.0028 0.0088 0.0306
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0047 0.0171 0.2213
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.0164 0.0569
Echinococcus granulosus g protein coupled receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0097 0.0389 1
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Mycobacterium leprae conserved hypothetical protein 0.0015 0.0027 0.0075
Echinococcus multilocularis lamin 0.0011 0.0013 0.0046
Brugia malayi sulfakinin receptor protein 0.0046 0.0164 0.0659
Trichomonas vaginalis sucrase-isomaltase, putative 0.0014 0.0026 0.0161
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0171 0.0719 0.0719
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.0164 0.0569
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0124 0.0511 0.1775
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Echinococcus granulosus poly ADP ribose polymerase 1 0.0067 0.026 0.0904
Onchocerca volvulus 0.0097 0.0389 0.2407
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0049 0.0179 0.4586
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0124 0.0511 0.2054
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0028 0.0088 0.0355
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.01 0.0404 0.2508
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0047 0.0171 0.4392
Schistosoma mansoni voltage-gated potassium channel 0.0014 0.0025 0.0088
Echinococcus granulosus neuropeptide receptor 0.0046 0.0164 0.0569
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0014 0.0026 0.0027
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.0164 0.0164
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0042 0.2203
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0097 0.0389 1
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0014 0.0025 0.0326
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0028 0.0088 0.0355
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0164 0.0569
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0067 0.0258 0.0897
Echinococcus granulosus sex peptide receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0011 0.0009 0.0009
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0042 0.2203
Brugia malayi Cation transporter family protein 0.0311 0.1333 0.5362
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0028 0.0088 0.4609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0181 0.0629
Brugia malayi Cation transporter family protein 0.0124 0.0511 0.2054
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.0164 0.0569
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0125 1
Onchocerca volvulus 0.0028 0.0088 0.0536
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0012
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0124 0.0511 0.0511
Mycobacterium tuberculosis Probable hydrolase 0.0015 0.0027 0.0697
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0042 0.0686
Echinococcus granulosus hypothetical protein 0.0046 0.0164 0.0569
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Plasmodium falciparum glutathione reductase 0.0052 0.0191 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Mycobacterium tuberculosis Probable aminotransferase 0.0044 0.0155 0.3991
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0014 0.0025 0.0326
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0124 0.0511 0.1775
Toxoplasma gondii ion channel protein 0.0028 0.0088 0.2554
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Brugia malayi Glycosyl hydrolases family 31 protein 0.0064 0.0246 0.0991
Echinococcus granulosus nAChR subunit 0.0067 0.0258 0.0897
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Onchocerca volvulus 0.0067 0.0258 0.1592
Onchocerca volvulus 0.0311 0.1333 0.8268
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.01 0.0404 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0082 0.0326 0.1133
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0042 0.1082
Trypanosoma cruzi ion transport protein, putative 0.0028 0.0088 0.4609
Brugia malayi Dopamine receptor 0.0046 0.0164 0.0659
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0011 0.0013 0.0044
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0036 0.0124 0.0497
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0125 0.6524
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.0164 0.0659
Mycobacterium tuberculosis Probable lipase LipD 0.0015 0.0027 0.0697
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.0164 0.0569
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0014 0.0025 0.0647
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0057 0.0216 0.075
Trichomonas vaginalis xanthine dehydrogenase, putative 0.01 0.0404 0.2507
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0164 0.0569
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0007 0.0026
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0028 0.0088 0.0088
Entamoeba histolytica hypothetical protein 0.001 0.0007 0.0184
Echinococcus multilocularis geminin 0.0355 0.1528 0.531
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0088 0.0547
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus granulosus intermediate filament protein 0.0011 0.0013 0.0046
Trypanosoma cruzi ion transport protein, putative 0.0028 0.0088 0.4609
Schistosoma mansoni alpha-glucosidase 0.0055 0.0207 0.0719
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0038 0.0129 0.6732
Schistosoma mansoni inositol monophosphatase 0.0037 0.0125 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0019 0.0046 0.0284
Loa Loa (eye worm) hypothetical protein 0.001 0.0007 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Onchocerca volvulus Neuropeptide F receptor homolog 0.0046 0.0164 0.1006
Leishmania major hypothetical protein, conserved 0.0011 0.0013 0.0658
Plasmodium vivax thioredoxin reductase, putative 0.0052 0.0191 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0057 0.0216 0.0216
Giardia lamblia Kinase, PLK 0.0038 0.0129 0.3185
Trypanosoma cruzi membrane transporter protein, putative 0.0011 0.0013 0.0658
Schistosoma mansoni neuropeptide receptor 0.0046 0.0164 0.0569
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0108 0.322
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0025 0.1318
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0059 0.0224 0.5745
Brugia malayi Carboxylesterase family protein 0.0097 0.0389 0.1566
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0164 0.0569
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0181 0.0629
Echinococcus granulosus lysosomal alpha glucosidase 0.0064 0.0246 0.0856
Schistosoma mansoni axis inhibition protein axin 0.001 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0097 0.0389 0.0389
Toxoplasma gondii thioredoxin reductase 0.0052 0.0191 0.6737
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Toxoplasma gondii ion channel protein 0.0028 0.0088 0.2554
Schistosoma mansoni hypothetical protein 0.0046 0.0164 0.0569
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.0164 0.0569
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0083 0.0083
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0028 0.0088 0.0306
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0171 0.0594
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0042 0.0146
Echinococcus multilocularis Polycystic kidney disease protein 0.0018 0.0041 0.0142
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0125 0.0434
Onchocerca volvulus 0.0028 0.0088 0.0536
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0015 0.0027 0.0697
Brugia malayi RE15519p 0.0046 0.0164 0.0659
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0124 0.0511 0.2054
Mycobacterium leprae Probable lipase LipE 0.0015 0.0027 0.0075
Loa Loa (eye worm) acetylcholine receptor protein 0.0057 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0067 0.0258 0.0258
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0009 0.0002 0.0095
Schistosoma mansoni histamine h1 receptor 0.0046 0.0164 0.0569
Leishmania major trypanothione reductase 0.0052 0.0191 1
Echinococcus multilocularis muscleblind protein 1 0.0146 0.0607 0.211
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0164 0.0569
Mycobacterium ulcerans hypothetical protein 0.0015 0.0027 0.0351
Loa Loa (eye worm) hypothetical protein 0.0332 0.1429 0.1429
Schistosoma mansoni lamin 0.0011 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Echinococcus granulosus lamin dm0 0.0011 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0164 0.0569
Schistosoma mansoni nAChR subunit 0.0124 0.0511 0.1775
Echinococcus multilocularis beta LACTamase domain containing family member 0.0015 0.0027 0.0094
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0124 0.0511 0.1775
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0072 0.0282 0.7237
Echinococcus granulosus c-Jun N-terminal kinases 0.0171 0.0719 0.2499
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0048 0.0176 0.0611
Schistosoma mansoni loxhd1 0.0018 0.0041 0.0142
Mycobacterium ulcerans hypothetical protein 0.0044 0.0155 0.2011
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0042 0.0914
Trichomonas vaginalis D-aminoacylase, putative 0.0015 0.0027 0.0168
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0124 0.0511 0.1775
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0002
Mycobacterium ulcerans ion transport protein 0.0028 0.0088 0.1141
Schistosoma mansoni neuropeptide receptor 0.0046 0.0164 0.0569
Onchocerca volvulus 0.0057 0.0216 0.1328
Plasmodium falciparum glutathione reductase 0.0018 0.0042 0.0086
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0124 0.0511 0.1775
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0028 0.0088 0.2182
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0059 0.0224 0.5745
Echinococcus granulosus biogenic amine 5HT receptor 0.0259 0.1104 0.3837
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0038 0.0129 0.0448
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0164 0.0569
Brugia malayi larval opioid receptor 0.0046 0.0164 0.0659
Brugia malayi beta-lactamase family protein 0.0015 0.0027 0.0109
Schistosoma mansoni jumonji/arid domain-containing protein 0.0031 0.0099 0.0345
Schistosoma mansoni lamin 0.0011 0.0013 0.0046
Loa Loa (eye worm) GABA receptor subunit 0.0067 0.0258 0.0258
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0028 0.0088 0.2264
Schistosoma mansoni hypothetical protein 0.0355 0.1528 0.531
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0164 0.0569
Brugia malayi Stress-activated protein kinase jnk-1 0.0171 0.0719 0.2891
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0042 0.2203
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0014 0.0025 0.0326
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0164 0.0569
Echinococcus multilocularis allatostatin A receptor 0.0046 0.0164 0.0569
Brugia malayi jmjC domain containing protein 0.0031 0.0099 0.0399
Echinococcus multilocularis sodium channel protein 0.0016 0.0032 0.011
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0025 0.0088
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0067 0.026 0.0904
Loa Loa (eye worm) hypothetical protein 0.0122 0.0501 0.0501
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0164 0.0569
Schistosoma mansoni twik family of potassium channels-related 0.0028 0.0088 0.0306
Brugia malayi hypothetical protein 0.0122 0.0501 0.2015
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0028 0.0088 0.0355
Brugia malayi hypothetical protein 0.0097 0.0389 0.1566
Schistosoma mansoni serine/threonine protein kinase 0.0038 0.0129 0.0448
Brugia malayi hypothetical protein 0.0046 0.0164 0.0659
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0048 0.0176 0.0707
Leishmania major DNA repair protein, putative 0.0009 0.0002 0.0095
Brugia malayi WGR domain containing protein 0.0037 0.0126 0.0508
Loa Loa (eye worm) RGS-3 protein 0.001 0.0007 0.0007
Loa Loa (eye worm) beta-lactamase 0.0015 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0164 0.0569
Schistosoma mansoni opsin-like receptor 0.0046 0.0164 0.0569
Loa Loa (eye worm) hypothetical protein 0.0124 0.0511 0.0511
Onchocerca volvulus 0.0028 0.0088 0.0536
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.0164 0.0164
Brugia malayi Regulator of G protein signaling domain containing protein 0.001 0.0007 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0027 0.1418
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0016 0.0032 0.011
Echinococcus granulosus axis inhibition protein axin 0.001 0.0007 0.0026
Trypanosoma brucei membrane transporter protein, putative 0.0011 0.0013 0.0658
Onchocerca volvulus 0.0124 0.0511 0.3161
Trypanosoma cruzi polo-like protein kinase, putative 0.0038 0.0129 0.6732
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0046 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0088 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0164 0.0569
Echinococcus granulosus acetylcholinesterase 0.0572 0.2486 0.8641
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0048 0.0176 0.0611
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0164 0.0569
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0072 0.0282 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0047 0.0171 0.0594
Echinococcus granulosus voltage dependent calcium channel 0.0048 0.0176 0.0611
Mycobacterium ulcerans hypothetical protein 0.0016 0.0035 0.045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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