Detailed information for compound 65548

Basic information

Technical information
  • TDR Targets ID: 65548
  • Name: 3-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1 -benzofuran-5-yl]-1,1-dimethylurea
  • MW: 391.461 | Formula: C20H29N3O5
  • H donors: 1 H acceptors: 1 LogP: 2.31 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(OCCN2CCCCC2)c(NC(=O)N(C)C)c(c2c1occ2)OC
  • InChi: 1S/C20H29N3O5/c1-22(2)20(24)21-15-16(25-3)14-8-12-27-17(14)19(26-4)18(15)28-13-11-23-9-6-5-7-10-23/h8,12H,5-7,9-11,13H2,1-4H3,(H,21,24)
  • InChiKey: ACGSMTAXGHZZAM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-[4,7-dimethoxy-6-[2-(1-piperidyl)ethoxy]benzofuran-5-yl]-1,1-dimethyl-urea
  • 3-[4,7-dimethoxy-6-[2-(1-piperidyl)ethoxy]-5-benzofuranyl]-1,1-dimethylurea
  • 3-[4,7-dimethoxy-6-(2-piperidin-1-ylethoxy)-1-benzofuran-5-yl]-1,1-dimethyl-urea
  • 3-[4,7-dimethoxy-6-(2-piperidinoethoxy)benzofuran-5-yl]-1,1-dimethyl-urea
  • 66203-06-3
  • BRN 1668433
  • N-(4,7-Dimethoxy-6-(2-piperidinoethoxy)-5-benzofuranyl)-N'-dimethylurea
  • Urea, 1-(4,7-dimethoxy-6-(2-piperidinoethoxy)-5-benzofuranyl)-3,3-dimethyl-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0609 0.3217 0.3807
Brugia malayi ecdysone receptor 0.0287 0.1471 0.1471
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.5839
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0111 0.0164
Onchocerca volvulus 0.0265 0.1349 0.4155
Schistosoma mansoni growth hormone secretagogue receptor 0.0265 0.1349 0.1984
Brugia malayi Doublecortin family protein 0.0059 0.0231 0.0231
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0287 0.1471 0.2164
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0499 0.4187
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0015 0.0022
Echinococcus multilocularis nuclear receptor nhr 48 0.0287 0.1471 0.2164
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0499 1
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0015 0.0022
Echinococcus granulosus intermediate filament protein 0.0027 0.0057 0.0149
Leishmania major cytochrome p450-like protein 0.0018 0.0007 0.0037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0291
Brugia malayi G-protein coupled receptor 0.0265 0.1349 0.1349
Echinococcus granulosus orexin receptor type 2 0.0265 0.1349 0.3515
Brugia malayi putative neuropeptide receptor 0.0265 0.1349 0.1349
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.1596
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0707 0.3751 0.9773
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0609 0.3217 0.8383
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0018 0.0007 0.0142
Brugia malayi G protein-coupled receptor F59B2.13 0.0265 0.1349 0.1349
Schistosoma mansoni thyroid hormone receptor 0.1269 0.6798 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0154 0.2907
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0609 0.3217 0.4732
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0016 0.0083
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0499 0.8904
Loa Loa (eye worm) nuclear hormone receptor 0.0287 0.1471 0.1736
Giardia lamblia PHD finger protein 15 0.0029 0.0069 0.0361
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0154 0.1295
Schistosoma mansoni hypothetical protein 0.0169 0.0828 0.1218
Echinococcus multilocularis neuropeptide s receptor 0.0723 0.3838 0.5645
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0111 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0609 0.3217 0.4732
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0051 0.019 0.1596
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Schistosoma mansoni hypothetical protein 0.0029 0.0069 0.0102
Loa Loa (eye worm) hypothetical protein 0.0369 0.1916 0.2264
Onchocerca volvulus Neuropeptide F receptor homolog 0.0265 0.1349 0.4155
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0096 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0057 0.0475
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0111 0.2017
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0052 0.0196 0.0289
Brugia malayi hypothetical protein 0.0322 0.1658 0.1658
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0318 0.1637 0.1637
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0019 0.0015 0.0293
Plasmodium falciparum phosphodiesterase gamma, putative 0.0051 0.019 0.5839
Echinococcus granulosus somatostatin receptor 0.0265 0.1349 0.3515
Echinococcus multilocularis sex peptide receptor 0.0265 0.1349 0.1984
Brugia malayi Nuclear hormone receptor-like 1 0.1571 0.844 0.844
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Schistosoma mansoni neuropeptide receptor 0.0265 0.1349 0.1984
Echinococcus granulosus chromobox protein 1 0.0081 0.035 0.0912
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.006
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0023 0.0035 0.0035
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Onchocerca volvulus 0.0049 0.0179 0.0496
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.007 0.0294 0.2462
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0051 0.019 0.5839
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Giardia lamblia hypothetical protein 0.0051 0.019 0.0994
Echinococcus granulosus allatostatin A receptor 0.0265 0.1349 0.3515
Schistosoma mansoni nuclear receptor nhr-48 0.0287 0.1471 0.2164
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0398 0.0585
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.019 0.1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0495 0.8837
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0609 0.3217 0.3217
Echinococcus multilocularis chromobox protein 2 0.0023 0.0035 0.0051
Schistosoma mansoni chromobox protein 0.0023 0.0035 0.0051
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0015 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0609 0.3217 0.3217
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0499 0.0735
Brugia malayi phosphofructokinase 0.0108 0.0499 0.0499
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0265 0.1349 0.1349
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0051 0.019 0.1
Brugia malayi orphan nuclear receptor NR2E1 0.0287 0.1471 0.1471
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0019 0.0015 0.0261
Echinococcus multilocularis ecdysone induced protein 78C 0.0609 0.3217 0.4732
Echinococcus multilocularis G protein coupled receptor 139 0.0265 0.1349 0.1984
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0042 0.0356
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0048 0.1464
Trypanosoma cruzi hypothetical protein, conserved 0.0212 0.1062 0.5581
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0016 0.0083
Brugia malayi Cytochrome P450 family protein 0.0026 0.0054 0.0054
Brugia malayi M-phase phosphoprotein, mpp8 0.0112 0.0521 0.0521
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0322 0.1658 0.1958
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Brugia malayi intermediate filament protein 0.0027 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0015 0.0022
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Brugia malayi Bromodomain containing protein 0.0038 0.0119 0.0119
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0237 0.0273
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0085 0.0371 0.3114
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.02 0.0563
Loa Loa (eye worm) inositol-1 0.0037 0.0111 0.0124
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0106 0.0156
Toxoplasma gondii endonuclease IV APN 0.0076 0.0326 0.1702
Brugia malayi G protein-coupled receptor 0.0265 0.1349 0.1349
Echinococcus granulosus peptide allatostatin:somatostatin 0.0265 0.1349 0.3515
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0609 0.3217 0.8383
Echinococcus multilocularis Protein lozenge 0.0055 0.0212 0.0312
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0445
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0015 0.0022
Loa Loa (eye worm) runx1 0.0055 0.0212 0.0243
Echinococcus granulosus sex peptide receptor 0.0265 0.1349 0.3515
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0013 0.0034
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0013 0.0402
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0048 0.0251
Echinococcus multilocularis serotonin receptor 0.0265 0.1349 0.1984
Brugia malayi hypothetical protein 0.0287 0.1471 0.1471
Onchocerca volvulus 0.0052 0.0196 0.055
Trichomonas vaginalis chromobox protein, putative 0.0053 0.02 0.168
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.056 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0291
Schistosoma mansoni hypothetical protein 0.066 0.3492 0.5137
Echinococcus granulosus tachykinin peptides receptor 99D 0.0265 0.1349 0.3515
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0104 0.0475 0.2494
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0015 0.0039
Echinococcus multilocularis FTZ F1 alpha 0.0609 0.3217 0.4732
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0015 0.0039
Brugia malayi MAP kinase sur-1 0.0051 0.0187 0.0187
Echinococcus multilocularis dro:myosuppressin receptor 0.0265 0.1349 0.1984
Echinococcus granulosus Nuclear hormone receptor HR96 0.0287 0.1471 0.3832
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.004
Onchocerca volvulus 0.0059 0.0231 0.066
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0106 0.0156
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0054 0.0056
Leishmania major DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Onchocerca volvulus 0.0265 0.1349 0.4155
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0386 0.2004 0.2948
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0231 0.034
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0265 0.1349 0.1984
Toxoplasma gondii thioredoxin reductase 0.0047 0.0167 0.0872
Schistosoma mansoni amine GPCR 0.0265 0.1349 0.1984
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.007 0.0367
Plasmodium falciparum GAF domain-related protein, putative 0.0019 0.0015 0.0449
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0576 0.3036 0.3592
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0265 0.1349 0.1984
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0111 0.0932
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0609 0.3217 0.3807
Giardia lamblia GTOR 0.0045 0.0154 0.0806
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0609 0.3217 0.4732
Schistosoma mansoni histamine h1 receptor 0.0265 0.1349 0.1984
Schistosoma mansoni adenoreceptor 0.0265 0.1349 0.1984
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.007 0.0294 0.0432
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Onchocerca volvulus 0.0059 0.0231 0.066
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0445
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Loa Loa (eye worm) melatonin receptor type 1A 0.0265 0.1349 0.1591
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0048 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0187 0.1568
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.007 0.0589
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0044 0.0784
Schistosoma mansoni zinc finger protein 0.0287 0.1471 0.2164
Schistosoma mansoni cytochrome P450 0.0018 0.0007 0.001
Brugia malayi Pre-SET motif family protein 0.0207 0.1037 0.1037
Brugia malayi GnHR receptor homolog 0.0265 0.1349 0.1349
Brugia malayi ecdysteroid receptor 0.0609 0.3217 0.3217
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.1191 0.1751
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0105 0.0551
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0016 0.0023
Onchocerca volvulus 0.0265 0.1349 0.4155
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Loa Loa (eye worm) hypothetical protein 0.0367 0.1904 0.2249
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.009 0.1611
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0051 0.019 0.1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0104 0.0475 0.2494
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0111 0.0584
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Trichomonas vaginalis hypothetical protein 0.0023 0.0035 0.0291
Schistosoma mansoni RAR-like nuclear receptor 0.0609 0.3217 0.4732
Echinococcus multilocularis g-protein coupled receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0287 0.1471 0.2164
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0051 0.019 0.1596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0357
Plasmodium falciparum phosphodiesterase delta, putative 0.0051 0.019 0.5839
Echinococcus granulosus cytochrome P450 2K1 0.0018 0.0007 0.0018
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0051 0.019 0.0218
Echinococcus granulosus neuropeptide Y receptor 0.0265 0.1349 0.3515
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0196 0.1641
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0111 0.0934
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0007 0.0126
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Trypanosoma brucei hypothetical protein, conserved 0.0051 0.019 0.1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0106 0.0106
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0111 0.0585
Schistosoma mansoni neuropeptide F-like receptor 0.0265 0.1349 0.1984
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0016 0.0083
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0035 0.0291
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0051 0.019 0.028
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.035 0.0407
Schistosoma mansoni amine GPCR 0.0265 0.1349 0.1984
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0167 0.5127
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0033
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0499 0.2624
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0013 0.0068
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0609 0.3217 0.4732
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0265 0.1349 0.1984
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0015 0.0449
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0499 0.0735
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.191
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0322 0.1658 0.2439
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0007 0.0037
Echinococcus multilocularis chromobox protein 1 0.0081 0.035 0.0515
Plasmodium falciparum thioredoxin reductase 0.0047 0.0167 0.5127
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0054 0.0286
Echinococcus granulosus tm gpcr rhodopsin 0.0265 0.1349 0.3515
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0069 0.0102
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0609 0.3217 0.4732
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Loa Loa (eye worm) G-protein coupled receptor 0.0265 0.1349 0.1591
Schistosoma mansoni lamin 0.0027 0.0057 0.0084
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0398 0.1036
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.019 0.1
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0111 0.029
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.007 0.0294 0.0294
Brugia malayi AKH receptor 0.0265 0.1349 0.1349
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0187 0.0275
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0007 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0018 0.0013
Schistosoma mansoni amine GPCR 0.0265 0.1349 0.1984
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Schistosoma mansoni chromobox protein 0.0081 0.035 0.0515
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0179 0.0263
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0025 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.019 0.1596
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0054 0.0056
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Schistosoma mansoni hypothetical protein 0.0018 0.0007 0.001
Onchocerca volvulus 0.0265 0.1349 0.4155
Echinococcus granulosus neuropeptides capa receptor 0.0265 0.1349 0.3515
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0048 0.1464
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0318 0.1637 0.4266
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0015 0.0022
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0154 0.0175
Brugia malayi neuropeptide F receptor 0.0265 0.1349 0.1349
Brugia malayi Nuclear hormone receptor-like 1 0.1571 0.844 0.844
Brugia malayi hypothetical protein 0.0059 0.0231 0.0231
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0016
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.1596
Onchocerca volvulus 0.0265 0.1349 0.4155
Loa Loa (eye worm) neuropeptide F receptor 0.0265 0.1349 0.1591
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.0511
Onchocerca volvulus 0.0609 0.3217 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0018 0.0007 0.0142
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0033 0.0049
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0111 0.0164
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.007 0.0294 0.0294
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0015 0.0039
Echinococcus granulosus peregrin 0.0031 0.0082 0.0213
Loa Loa (eye worm) hypothetical protein 0.0051 0.019 0.0218
Loa Loa (eye worm) hypothetical protein 0.0441 0.2308 0.2728
Echinococcus granulosus fmrfamide receptor 0.0265 0.1349 0.3515
Onchocerca volvulus 0.0265 0.1349 0.4155
Mycobacterium ulcerans endonuclease IV 0.0076 0.0326 0.6528
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0367 0.1904 0.1904
Brugia malayi Serotonin receptor 0.0265 0.1349 0.1349
Loa Loa (eye worm) doublecortin family protein 0.0059 0.0231 0.0266
Schistosoma mansoni neuropeptide F-like receptor 0.0265 0.1349 0.1984
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0069 0.0102
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0268 0.141
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0018 0.0007 0.0142
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0007 0.0126
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0287 0.1471 0.4537
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0228 0.1147 0.1687
Echinococcus granulosus tm gpcr rhodopsin 0.0265 0.1349 0.3515
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0609 0.3217 0.4732
Brugia malayi nuclear receptor NHR-67 0.0287 0.1471 0.1471
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Trypanosoma brucei trypanothione reductase 0.0047 0.0167 0.0878
Echinococcus multilocularis neuropeptide Y receptor 0.0265 0.1349 0.1984
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0085 0.0371 0.3114
Echinococcus granulosus neuropeptide receptor A26 0.0723 0.3838 1
Brugia malayi jmjC domain containing protein 0.0037 0.0113 0.0113
Chlamydia trachomatis endonuclease IV 0.0076 0.0326 1
Schistosoma mansoni survival motor neuron protein 0.0048 0.0172 0.0253
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0154 0.0812
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0107
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0033 0.0049
Echinococcus granulosus neuropeptide Y receptor 0.0265 0.1349 0.3515
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0187 0.0983
Echinococcus granulosus tm gpcr rhodopsin 0.0265 0.1349 0.3515
Brugia malayi RE15519p 0.0265 0.1349 0.1349
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0018 0.0007 0.0142
Brugia malayi Tachykinin-like peptides receptor 99D 0.0265 0.1349 0.1349
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.019 0.1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0023
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.007 0.0294 0.0432
Brugia malayi nuclear receptor RXR 0.0287 0.1471 0.1471
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0609 0.3217 0.3217
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0015 0.001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0067 0.0174
Loa Loa (eye worm) hypothetical protein 0.005 0.0181 0.0206
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0044 0.0231
Schistosoma mansoni biogenic amine receptor 0.0265 0.1349 0.1984
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Brugia malayi nuclear receptor RXR 0.0322 0.1658 0.1658
Brugia malayi nuclear receptor NHR-88 0.0287 0.1471 0.1471
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0609 0.3217 0.3217
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0265 0.1349 0.3515
Leishmania major hypothetical protein, conserved 0.0212 0.1062 0.5581
Schistosoma mansoni lipoxygenase 0.0121 0.0571 0.084
Brugia malayi nuclear hormone receptor family member nhr-6 0.0287 0.1471 0.1471
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0609 0.3217 0.3807
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0007 0.0126
Onchocerca volvulus 0.0287 0.1471 0.4537
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.007 0.0367
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0265 0.1349 0.1984
Echinococcus granulosus Chromobox protein 3 0.0023 0.0035 0.0091
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0268 0.5251
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0265 0.1349 0.1591
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0184 0.1545
Echinococcus multilocularis lamin 0.0027 0.0057 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0187 0.1568
Echinococcus multilocularis serotonin receptor 0.0265 0.1349 0.1984
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0019 0.0015 0.0261
Onchocerca volvulus 0.0265 0.1349 0.4155
Plasmodium falciparum glutathione reductase 0.0047 0.0167 0.5127
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0069 0.0361
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0265 0.1349 0.1984
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0016 0.0023
Schistosoma mansoni bromodomain containing protein 0.0063 0.0254 0.0373
Brugia malayi sulfakinin receptor protein 0.0265 0.1349 0.1349
Schistosoma mansoni chromobox protein 0.0023 0.0035 0.0051
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0051 0.019 0.028
Schistosoma mansoni opsin-like receptor 0.0265 0.1349 0.1984
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0007 0.0126
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.1191 0.3103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.007 0.0589
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.0726 0.0853
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0231 0.0603
Brugia malayi Cytochrome P450 family protein 0.0018 0.0007 0.0007
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0154 0.0812
Echinococcus granulosus serotonin receptor 0.0265 0.1349 0.3515
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0326 0.0326
Brugia malayi nuclear hormone receptor 0.0287 0.1471 0.1471
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0051 0.019 0.028
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0018 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.019 0.1596
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0609 0.3217 0.3217
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0214 0.0245
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0054 0.1091
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0051 0.019 0.019
Echinococcus multilocularis G-protein coupled receptor, putative 0.0265 0.1349 0.1984
Loa Loa (eye worm) glutathione reductase 0.0047 0.0167 0.019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0609 0.3217 0.3217
Brugia malayi hypothetical protein 0.0163 0.0794 0.0794
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0111 0.0932
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0499 1
Brugia malayi PXA domain containing protein 0.0019 0.0015 0.0015
Schistosoma mansoni intermediate filament proteins 0.0027 0.0057 0.0084
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0104 0.0475 0.2494
Brugia malayi hypoxia-induced factor 1 0.015 0.0726 0.0726
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.5839
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0105 0.0551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0609 0.3217 0.3807
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0111 0.058
Trypanosoma cruzi hypothetical protein, conserved 0.0212 0.1062 0.5581
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0187 0.0214
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Loa Loa (eye worm) G-protein coupled receptor 0.0265 0.1349 0.1591
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0051 0.019 0.1596
Echinococcus granulosus ecdysone induced protein 78C 0.0609 0.3217 0.8383
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0051 0.019 0.028
Echinococcus granulosus single minded 2 0.0036 0.0106 0.0277
Schistosoma mansoni hypothetical protein 0.0034 0.0096 0.0141
Loa Loa (eye worm) hypothetical protein 0.007 0.0294 0.034
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Loa Loa (eye worm) TYRA-2 protein 0.0265 0.1349 0.1591
Onchocerca volvulus 0.0265 0.1349 0.4155
Mycobacterium ulcerans epimerase 0.002 0.002 0.0409
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Echinococcus granulosus neuropeptide s receptor 0.0723 0.3838 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0026 0.0138
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Echinococcus multilocularis zinc finger protein 0.002 0.0017 0.0025
Loa Loa (eye worm) PDE1B protein 0.0051 0.019 0.0218
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0357
Mycobacterium tuberculosis Probable reductase 0.0108 0.0495 0.8837
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0499 1
Echinococcus multilocularis g protein coupled receptor 0.0265 0.1349 0.1984
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0495 0.8822
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0609 0.3217 0.3217
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.031 0.0456
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus granulosus Nuclear hormone receptor HR96 0.0287 0.1471 0.3832
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0018 0.0007 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.0878
Loa Loa (eye worm) hypothetical protein 0.0059 0.0231 0.0266
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0154 0.1295
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.019 0.1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0113 0.0166
Schistosoma mansoni amine GPCR 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0499 0.2624
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0287 0.1471 0.2164
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0495 0.8837
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0187 0.1568
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0013 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0007 0.0126
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0187 0.1568
Trypanosoma brucei protein kinase, putative 0.0051 0.0187 0.0983
Brugia malayi Bromodomain containing protein 0.0031 0.0082 0.0082
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0367 0.1904 1
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0499 1
Schistosoma mansoni neuropeptide receptor 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0049 0.0179 0.0204
Echinococcus multilocularis allatostatin A receptor 0.0265 0.1349 0.1984
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0015 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0609 0.3217 0.3217
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0012 0.0065
Echinococcus multilocularis Polycystic kidney disease protein 0.0059 0.0231 0.034
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0234 0.0345
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Brugia malayi hypothetical protein 0.0019 0.0015 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0053 0.02 0.168
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0018 0.0007 0.0142
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0035 0.1065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0609 0.3217 0.3217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0069 0.0074
Brugia malayi hypothetical protein 0.0112 0.0522 0.0522
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0187 0.0976
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0102 0.015
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.0463
Mycobacterium leprae conserved hypothetical protein 0.002 0.002 0.0241
Brugia malayi conserved hypotetical protein 0.0287 0.1471 0.1471
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0013 0.011
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0092 0.0481
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0016 0.0083
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0018 0.0007 0.0142
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0126
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.5839
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0051 0.019 0.028
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0187 0.0275
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0018 0.0007 0.0037
Echinococcus granulosus neuropeptide receptor 0.0265 0.1349 0.3515
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0126
Echinococcus granulosus chromobox protein 1 0.0081 0.035 0.0912
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0265 0.1349 0.3515
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.007 0.0294 0.2462
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0018 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0609 0.3217 0.8383
Echinococcus multilocularis chromobox protein 1 0.0081 0.035 0.0515
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0033
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0044 0.0879
Echinococcus granulosus tumor protein p63 0.0337 0.1739 0.4532
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.007 0.0367
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0015 0.0022
Toxoplasma gondii hypothetical protein 0.0052 0.0196 0.1021
Brugia malayi follicle stimulating hormone receptor 0.0265 0.1349 0.1349
Brugia malayi steroid hormone receptor 0.0609 0.3217 0.3217
Mycobacterium ulcerans hypothetical protein 0.002 0.002 0.0409
Schistosoma mansoni inositol monophosphatase 0.0037 0.0111 0.0164
Schistosoma mansoni polycystin 1-related 0.0059 0.0231 0.034
Echinococcus granulosus neuropeptides capa receptor 0.0265 0.1349 0.3515
Loa Loa (eye worm) DR-78 0.0287 0.1471 0.1736
Loa Loa (eye worm) hypothetical protein 0.0112 0.0522 0.061
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0428 0.0629
Schistosoma mansoni inositol monophosphatase 0.0037 0.0111 0.0164
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0051 0.019 0.028
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0051 0.019 0.0496
Schistosoma mansoni rab6-interacting 0.0059 0.0231 0.034
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0268 0.141
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0268 0.141
Brugia malayi Nuclear hormone receptor E75 0.0287 0.1471 0.1471
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0118 0.0308
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.002 0.0409
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0111 0.029
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0007 0.0126
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0609 0.3217 0.8383
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.007 0.2154
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0322 0.1658 0.432
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0265 0.1349 0.1591
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0111 0.0164
Brugia malayi hypothetical protein 0.0025 0.0048 0.0048
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0265 0.1349 0.1591
Entamoeba histolytica hypothetical protein 0.0023 0.0035 0.0445
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0051 0.019 0.0496
Trypanosoma brucei C-8 sterol isomerase, putative 0.0367 0.1904 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0231 0.0266
Brugia malayi tailless protein 0.0287 0.1471 0.1471
Giardia lamblia DINP protein human, muc B family 0.0019 0.0016 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Echinococcus multilocularis neuropeptide Y receptor 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.0878
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0187 0.0983
Loa Loa (eye worm) nuclear receptor NHR-67 0.0287 0.1471 0.1736
Echinococcus granulosus g protein coupled receptor 0.0265 0.1349 0.3515
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0265 0.1349 0.1984
Brugia malayi putative neuropeptide receptor NPR1 0.0265 0.1349 0.1349
Echinococcus multilocularis neuropeptide receptor 0.0265 0.1349 0.1984
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0495 0.8837
Brugia malayi nuclear hormone receptor 0.0609 0.3217 0.3217
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0051 0.019 0.1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0018 0.0013
Schistosoma mansoni steroid hormone receptor ad4bp 0.0609 0.3217 0.4732
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0018 0.0007 0.0142
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0106 0.0276
Echinococcus granulosus biogenic amine 5HT receptor 0.0265 0.1349 0.3515
Echinococcus granulosus geminin 0.0169 0.0828 0.2158
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.019 0.1
Echinococcus multilocularis Chromobox protein 3 0.0023 0.0035 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0126
Schistosoma mansoni retinoic acid receptor RXR 0.0707 0.3751 0.5517
Mycobacterium tuberculosis Conserved protein 0.0024 0.0044 0.0784
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0015 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0013 0.0069
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0018 0.0007 0.0142
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0035 0.1065
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0184 0.0513
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0015 0.0022
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0287 0.1471 0.2164
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0015 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Trichomonas vaginalis chromobox protein, putative 0.0081 0.035 0.2934
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0016 0.0316
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0015 0.0039
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0106 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Plasmodium falciparum LCCL domain-containing protein 0.0059 0.0231 0.7096
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0165 0.0243
Echinococcus multilocularis somatostatin receptor 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0076 0.0326 0.0378
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0007 0.0126
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0154 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0196 0.1641
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0499 0.2624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0119 0.0997
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Onchocerca volvulus 0.0265 0.1349 0.4155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0609 0.3217 0.3807
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0018 0.0007 0.0142
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0054 0.0286
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0018 0.0007 0.0142
Onchocerca volvulus 0.0265 0.1349 0.4155
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.0878
Brugia malayi PHD-finger family protein 0.0029 0.0069 0.0069
Loa Loa (eye worm) helicase 0.0023 0.0035 0.0033
Echinococcus granulosus g-protein coupled receptor 0.0265 0.1349 0.3515
Schistosoma mansoni lamin 0.0027 0.0057 0.0084
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0051 0.019 0.1
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0357
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0369 0.1916 0.2818
Brugia malayi SET domain containing protein 0.0024 0.0041 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Schistosoma mansoni hypothetical protein 0.0265 0.1349 0.1984
Schistosoma mansoni biogenic amine (5HT) receptor 0.0265 0.1349 0.1984
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0016
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0172 0.0172
Schistosoma mansoni nuclear hormone receptor 0.0287 0.1471 0.2164
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0154 0.0812
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0369 0.1916 0.2818
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0165 0.0243
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Onchocerca volvulus Bile acid receptor homolog 0.0609 0.3217 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.007 0.0589
Onchocerca volvulus Protein ultraspiracle homolog 0.0609 0.3217 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0265 0.1349 0.3515
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0069 0.0074
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0111 0.0164
Brugia malayi Inositol-1 0.0037 0.0111 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0007 0.0126
Brugia malayi Heterochromatin protein 1 0.0081 0.035 0.035
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.191
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0369 0.1916 0.4993
Echinococcus multilocularis neuropeptides capa receptor 0.0265 0.1349 0.1984
Echinococcus granulosus RUN 0.0059 0.0231 0.0603
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1571 0.844 1
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Echinococcus multilocularis lamin dm0 0.0027 0.0057 0.0084
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0499 0.1301
Plasmodium vivax glutathione reductase, putative 0.0047 0.0167 0.5127
Echinococcus granulosus Chromo domain 0.0023 0.0035 0.0091
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0265 0.1349 0.1984
Brugia malayi CHD4 protein 0.0025 0.0045 0.0045
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0104 0.0475 0.398
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0175 0.0257
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0165 0.043
Schistosoma mansoni ap endonuclease 0.0019 0.0013 0.0019
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0015 0.0293
Brugia malayi photoreceptor-specific nuclear receptor 0.0609 0.3217 0.3217
Leishmania major cytochrome p450-like protein 0.0018 0.0007 0.0037
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0499 0.0584
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.1
Loa Loa (eye worm) hypothetical protein 0.0188 0.093 0.1094
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0035 0.0291
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0051 0.019 0.1596
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.5839
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0167 0.0878
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0023 0.0035 0.0181
Echinococcus granulosus dna polymerase kappa 0.0019 0.0016 0.0041
Onchocerca volvulus 0.0048 0.0172 0.0475
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0187 0.0487
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0265 0.1349 0.1984
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0196 0.1641
Echinococcus granulosus jumonji domain containing protein 0.004 0.0131 0.0341
Loa Loa (eye worm) hypothetical protein 0.0236 0.1191 0.1404
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0495 0.8837
Loa Loa (eye worm) hypothetical protein 0.0043 0.0142 0.016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0609 0.3217 0.3217
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0015 0.001
Brugia malayi glutathione reductase 0.0047 0.0167 0.0167
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0018 0.0007 0.0142
Loa Loa (eye worm) hypothetical protein 0.0322 0.1658 0.1958
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0016 0.0083
Echinococcus granulosus biogenic amine 5HT receptor 0.0265 0.1349 0.3515
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Brugia malayi chromobox protein homolog 3 0.005 0.0184 0.0184
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0051 0.019 0.028
Loa Loa (eye worm) hypothetical protein 0.0322 0.1658 0.1958
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0287 0.1471 0.4537
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0013 0.1178
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0013 0.0019
Brugia malayi Pre-SET motif family protein 0.003 0.0073 0.0073
Schistosoma mansoni neuropeptide receptor 0.0265 0.1349 0.1984
Schistosoma mansoni biogenic amine (5HT) receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0015 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0265 0.1349 0.1984
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0268 0.0395
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0322 0.1658 0.2439
Schistosoma mansoni opsin-like receptor 0.0265 0.1349 0.1984
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.007 0.0294 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0069 0.058
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Schistosoma mansoni coup transcription factor 0.0609 0.3217 0.4732
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0154 0.0154
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Onchocerca volvulus 0.0027 0.0057 0.0115
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0187 0.0983
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0073 0.038
Loa Loa (eye worm) hypothetical protein 0.0041 0.0132 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0609 0.3217 0.3217
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0609 0.3217 0.4732
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Brugia malayi small heat shock protein 0.0576 0.3036 0.3036
Toxoplasma gondii exonuclease III APE 0.0019 0.0013 0.0068
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0057
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0051 0.019 0.1
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0018 0.0007 0.0142
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0287 0.1471 0.3832
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0015 0.0022
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0154 0.0812
Brugia malayi Associated with TFs and helicases family protein 0.0023 0.0035 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0236 0.1193 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.1269 0.6798 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0013 0.0069
Brugia malayi Melatonin receptor type 1A 0.0265 0.1349 0.1349
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0111 0.029
Brugia malayi Cytochrome P450 family protein 0.0026 0.0054 0.0054
Trypanosoma brucei hypothetical protein, conserved 0.0212 0.1062 0.5581
Echinococcus multilocularis expressed protein 0.0372 0.1931 0.284
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.007 0.1175
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0499 0.0735
Schistosoma mansoni DNA polymerase eta 0.0019 0.0016 0.0023
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0369 0.1916 0.2818
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.0511
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0609 0.3217 0.3807
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0033 0.0087
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0044 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0085 0.0371 0.1951
Brugia malayi hypothetical protein 0.0441 0.2308 0.2308
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0015 0.0022
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0015 0.0293
Brugia malayi larval opioid receptor 0.0265 0.1349 0.1349
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0181 0.0181
Echinococcus multilocularis neuropeptide receptor 0.0265 0.1349 0.1984
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0265 0.1349 0.1984
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0104 0.0475 0.0698
Echinococcus granulosus neuropeptide FF receptor 2 0.0265 0.1349 0.3515
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0499 0.0584
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0369 0.1916 0.4993
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0265 0.1349 0.4155
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.002 0.0364
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.007 0.0589
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0013 0.0069
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0018 0.0007 0.0037
Echinococcus multilocularis fmrfamide receptor 0.0265 0.1349 0.1984
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0369 0.1916 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.0878
Schistosoma mansoni hypothetical protein 0.0021 0.0023 0.0034
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0228 0.1147 0.2988
Toxoplasma gondii hypothetical protein 0.0019 0.0015 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0154 0.1295
Toxoplasma gondii hypothetical protein 0.0019 0.0015 0.0076
Echinococcus granulosus Polycystic kidney disease protein 0.0059 0.0231 0.0603
Brugia malayi nuclear hormone receptor family member odr-7 0.0287 0.1471 0.1471
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0015 0.001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0265 0.1349 0.1984
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0187 0.0983
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0054 0.0056
Echinococcus multilocularis neuropeptide receptor A26 0.0723 0.3838 0.5645
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0398 0.0585
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0007 0.0126
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0044 0.0231
Brugia malayi hypothetical protein 0.0059 0.0231 0.0231
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0044 0.0368
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0013 0.0234
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.007 0.1406
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.007 0.0367
Schistosoma mansoni biogenic amine receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0231 0.034
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0007 0.0126
Brugia malayi Bromodomain containing protein 0.0075 0.0317 0.0317
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.007 0.2154
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.066 0.3492 0.91
Onchocerca volvulus Alhambra homolog 0.0029 0.0069 0.0152
Loa Loa (eye worm) hypothetical protein 0.0051 0.019 0.0218
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0035 0.0181
Plasmodium vivax phosphodiesterase gamma, putative 0.0051 0.019 0.5839
Loa Loa (eye worm) hypothetical protein 0.0441 0.2308 0.2728
Brugia malayi Valyl-tRNA synthetase 0.0023 0.0035 0.0035
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0051 0.019 0.019
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0104 0.0475 0.398
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0322 0.0473
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0265 0.1349 0.1984
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.007 0.2154
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni ap endonuclease 0.0019 0.0013 0.0019
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0167 0.019
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0007 0.0126
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0231 0.0603
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0499 1
Brugia malayi ORL1-like opioid receptor 0.0265 0.1349 0.1349
Loa Loa (eye worm) hypothetical protein 0.0034 0.0096 0.0105
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0268 0.141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Echinococcus granulosus dna polymerase eta 0.0019 0.0016 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0126
Echinococcus granulosus alpha 1A adrenergic receptor 0.0265 0.1349 0.3515
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0013 0.0262
Schistosoma mansoni nuclear hormone receptor 0.0609 0.3217 0.4732
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0187 0.0487
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0051 0.019 0.028
Onchocerca volvulus 0.0112 0.0521 0.1566
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0025 0.0045 0.0117
Plasmodium falciparum heterochromatin protein 1 0.0023 0.0035 0.1065
Onchocerca volvulus 0.0441 0.2308 0.7155
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.056 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0167 0.2985
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0265 0.1349 0.1984
Schistosoma mansoni neuropeptide receptor 0.0265 0.1349 0.1984
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0016 0.0023
Loa Loa (eye worm) steroid hormone receptor 0.0609 0.3217 0.3807
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0074 0.0624
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0018 0.0007 0.0142
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus granulosus nuclear receptor nhr 48 0.0287 0.1471 0.3832
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Loa Loa (eye worm) hypothetical protein 0.0322 0.1658 0.1958
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0265 0.1349 0.1349
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0051 0.019 0.019
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0051 0.019 0.028
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Loa Loa (eye worm) hypothetical protein 0.0038 0.0119 0.0133
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0022
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0154 0.0403
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0131 0.0192
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0111 0.0111
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0016 0.0281
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0268 0.031
Schistosoma mansoni hypothetical protein 0.0036 0.0106 0.0156
Echinococcus multilocularis g protein coupled receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0051 0.019 0.028
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0326 1
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0111 0.0934
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.002 0.002
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0007 0.0126
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0016 0.0281
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0609 0.3217 0.3217
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0015 0.0126
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0154 0.0812
Trichomonas vaginalis Heterochromatin protein, putative 0.0023 0.0035 0.0291
Brugia malayi 6-phosphofructokinase 0.0108 0.0499 0.0499
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0069 0.0361
Echinococcus granulosus expressed protein 0.0372 0.1931 0.5031
Trypanosoma brucei unspecified product 0.0019 0.0016 0.0083
Brugia malayi Dopamine receptor protein 1 0.0265 0.1349 0.1349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0265 0.1349 0.1984
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.056 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Onchocerca volvulus 0.0265 0.1349 0.4155
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.066 0.3492 0.5137
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0111 0.0164
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Leishmania major hypothetical protein, conserved 0.0051 0.019 0.1
Echinococcus multilocularis dna polymerase eta 0.0019 0.0016 0.0023
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0111 0.0584
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0265 0.1349 0.1984
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0609 0.3217 0.8383
Leishmania major cAMP-specific phosphodiesterase, putative 0.0051 0.019 0.1
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0051 0.019 0.028
Loa Loa (eye worm) hypothetical protein 0.0322 0.1658 0.1958
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0318 0.1637 0.2408
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0035 0.0291
Entamoeba histolytica hypothetical protein 0.0023 0.0035 0.0445
Brugia malayi PHD-finger family protein 0.0025 0.0046 0.0046
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0018 0.0007 0.0142
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0609 0.3217 0.8383
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0187 0.0983
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0018 0.0007 0.0037
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0054 0.0286
Loa Loa (eye worm) hypothetical protein 0.0047 0.0165 0.0188
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0016 0.0316
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0023 0.0035 0.0051
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0048 0.0251
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0265 0.1349 0.1591
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Leishmania major cytochrome p450-like protein 0.0026 0.0054 0.0286
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0015 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0265 0.1349 0.1984
Brugia malayi hypothetical protein 0.0019 0.0015 0.0015
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0073 0.0107
Schistosoma mansoni lipoxygenase 0.0228 0.1147 0.1687
Giardia lamblia Hypothetical protein 0.0051 0.019 0.0994
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.1596
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0007 0.0126
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0113 0.0125
Echinococcus multilocularis geminin 0.0169 0.0828 0.1218
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0291
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0318 0.1637 0.1933
Echinococcus granulosus g protein coupled receptor 0.0265 0.1349 0.3515
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0018 0.0007 0.0142
Brugia malayi Steroid receptor seven-up type 2 0.0609 0.3217 0.3217
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0609 0.3217 1
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Echinococcus multilocularis musashi 0.0027 0.0057 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0123
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.5839
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.007 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0016 0.0083
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0051 0.019 0.1596
Brugia malayi neuropeptide F receptor 0.0265 0.1349 0.1349
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.191
Brugia malayi Dopamine receptor protein 2 0.0265 0.1349 0.1349
Schistosoma mansoni nuclear receptor 0.0287 0.1471 0.2164
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0111 0.0585
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.007 0.2154
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0018 0.0026
Echinococcus multilocularis RUN 0.0059 0.0231 0.034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0609 0.3217 0.3217
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0016 0.001
Entamoeba histolytica hypothetical protein 0.0023 0.0035 0.0445
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0287 0.1471 0.3832
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0083
Plasmodium vivax SET domain protein, putative 0.003 0.0073 0.2235
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0167 0.0246
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Brugia malayi PAS domain containing protein 0.0048 0.0175 0.0175
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0369 0.1916 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0322 0.1658 0.2439
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0007 0.0126
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0265 0.1349 0.3515
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0015 0.0022
Toxoplasma gondii GAF domain-containing protein 0.0019 0.0015 0.0076
Echinococcus multilocularis Chromo domain 0.0023 0.0035 0.0051
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0051 0.019 0.1596
Brugia malayi Serotonin receptor 0.0265 0.1349 0.1349
Onchocerca volvulus 0.0036 0.0106 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0018 0.0007 0.0142
Brugia malayi Protein cec-1. 0.0023 0.0035 0.0035
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0499 0.0584
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0398 0.0585
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0265 0.1349 0.1349
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0004 0.0009
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0499 0.8918
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0234 0.0611
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0023 0.0019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0265 0.1349 0.1984
Schistosoma mansoni hypothetical protein 0.0169 0.0828 0.1218
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0265 0.1349 0.1984
Schistosoma mansoni hypothetical protein 0.0265 0.1349 0.1984
Schistosoma mansoni single-minded 0.0048 0.0175 0.0257
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0326 0.5768
Schistosoma mansoni lozenge 0.0055 0.0212 0.0312
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0048 0.1464
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0022
Brugia malayi Nuclear hormone receptor E75 0.0287 0.1471 0.1471
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.056 1
Brugia malayi hypothetical protein 0.0322 0.1658 0.1658
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0113 0.0293
Schistosoma mansoni hypothetical protein 0.0048 0.0172 0.0253
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0007 0.0126
Mycobacterium ulcerans hypothetical protein 0.0024 0.0044 0.0879
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0004 0.0005
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0265 0.1349 0.1349
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0044 0.0879
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0104 0.0475 0.1237
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0015 0.0022
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Loa Loa (eye worm) hypothetical protein 0.005 0.0182 0.0207
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0265 0.1349 0.3515
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0015 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.0463
Schistosoma mansoni opsin-like receptor 0.0265 0.1349 0.1984
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0287 0.1471 0.2164
Schistosoma mansoni zinc finger protein 0.002 0.0017 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0015 0.0022
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0154 0.0812
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.1037 0.1222
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0023 0.0035 0.1065
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0268 0.0395
Loa Loa (eye worm) neuropeptide F receptor 0.0265 0.1349 0.1591
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0287 0.1471 0.1736
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0057 0.0475
Echinococcus granulosus 7TM GPCR rhodopsin 0.0265 0.1349 0.3515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0187 0.0275
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0499 0.4187
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0013 0.011
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0265 0.1349 0.1984
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.007 0.0589
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0326 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0609 0.3217 0.3807
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0057 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0126
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0106 0.0276
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.0005
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0265 0.1349 0.1984
Plasmodium falciparum phd finger protein, putative 0.0029 0.0069 0.2119
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.007 0.2154
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0013 0.0069
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0104 0.0475 0.0698
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0265 0.1349 0.1984
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0265 0.1349 0.1984
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0111 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0184 0.1545
Brugia malayi G-protein coupled receptor 0.0265 0.1349 0.1349
Schistosoma mansoni loxhd1 0.0059 0.0231 0.034
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0051 0.019 0.019
Echinococcus multilocularis neuropeptides capa receptor 0.0265 0.1349 0.1984
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0051 0.019 0.1
Loa Loa (eye worm) hypothetical protein 0.0163 0.0794 0.0934
Onchocerca volvulus 0.0287 0.1471 0.4537
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0104 0.0475 0.2494
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0287 0.1471 0.2164
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0104 0.0475 0.2494
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0187 0.0983
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Leishmania major DNA polymerase eta, putative 0.0019 0.0016 0.0083
Onchocerca volvulus 0.0265 0.1349 0.4155
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0069 0.2119
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0111 0.0932
Entamoeba histolytica hypothetical protein 0.0019 0.0015 0.004
Onchocerca volvulus 0.0265 0.1349 0.4155
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.0005
Schistosoma mansoni amine GPCR 0.0265 0.1349 0.1984
Schistosoma mansoni nuclear receptor 0.0287 0.1471 0.2164
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0609 0.3217 0.4732
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0013 0.0402
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0051 0.019 0.0496
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0265 0.1349 0.1984
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Loa Loa (eye worm) hypothetical protein 0.1537 0.8253 0.9778
Brugia malayi PXA domain containing protein 0.0019 0.0015 0.0015
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0023 0.0035 0.0181
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0048 0.0251
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0016 0.0132
Schistosoma mansoni hypothetical protein 0.0023 0.0035 0.0051
Leishmania major hypothetical protein, conserved 0.0025 0.0048 0.0251
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.019 0.1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0104 0.0475 0.398
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0092 0.0773
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.001
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0051 0.019 0.028
Echinococcus granulosus FTZ F1 alpha 0.0609 0.3217 0.8383
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0051 0.019 0.0496
Schistosoma mansoni hypothetical protein 0.0265 0.1349 0.1984
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0154 0.2907
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0018 0.0018
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0268 0.07
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0499 0.4187
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0007 0.0126
Brugia malayi Cytochrome P450 family protein 0.0056 0.0214 0.0214
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0609 0.3217 0.4732
Schistosoma mansoni thyroid hormone receptor 0.1269 0.6798 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0037 0.0111 0.0124
Trichomonas vaginalis chromobox protein, putative 0.0081 0.035 0.2934
Echinococcus granulosus hypothetical protein 0.0265 0.1349 0.3515
Trichomonas vaginalis chromobox protein, putative 0.0023 0.0035 0.0291
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0265 0.1349 0.1591
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.001
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0051 0.019 0.1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.031 0.0807
Schistosoma mansoni hypothetical protein 0.0059 0.0231 0.034
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0023 0.0035 0.1065
Echinococcus granulosus g protein coupled receptor 0.0265 0.1349 0.3515
Brugia malayi jmjC domain containing protein 0.0095 0.0428 0.0428
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0187 0.0983
Echinococcus granulosus thyroid hormone receptor alpha 0.0287 0.1471 0.3832
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0016 0.0055
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0187 0.0976
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Onchocerca volvulus 0.0031 0.0077 0.0177
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0428 0.1115
Brugia malayi hypothetical protein 0.0236 0.1191 0.1191
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Brugia malayi nuclear receptor NHR-88 0.0609 0.3217 0.3217
Brugia malayi hypothetical protein 0.0036 0.0106 0.0106
Schistosoma mansoni chromobox protein 0.0081 0.035 0.0515
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0111 0.0585
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0165 0.0243
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0111 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0015 0.0126
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0035 0.0051
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0018 0.0007 0.0142
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0265 0.1349 0.3515
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0007 0.0126
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.001
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0035 0.0291
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0051 0.019 0.1596
Leishmania major trypanothione reductase 0.0047 0.0167 0.0878
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0018 0.0007 0.0037
Brugia malayi Thioredoxin reductase 0.0047 0.0167 0.0167
Schistosoma mansoni neuropeptide f receptor 76f 0.0265 0.1349 0.1984
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0018 0.0007 0.0142
Plasmodium vivax multidomain scavenger receptor, putative 0.0059 0.0231 0.7096
Schistosoma mansoni alpha-1 adrenergic receptor 0.0265 0.1349 0.1984
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0016 0.0132
Onchocerca volvulus 0.0265 0.1349 0.4155
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.191
Toxoplasma gondii cytochrome p450 superfamily protein 0.0018 0.0007 0.0037
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0051 0.019 0.5839
Echinococcus granulosus dro:myosuppressin receptor 0.0265 0.1349 0.3515
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0105 0.0551
Schistosoma mansoni biogenic amine receptor 0.0265 0.1349 0.1984
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0287 0.1471 0.1471
Onchocerca volvulus 0.0236 0.1194 0.367
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0044 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.007 0.0589
Echinococcus granulosus chromobox protein 2 0.0023 0.0035 0.0091
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0016 0.0083
Loa Loa (eye worm) hypothetical protein 0.007 0.0294 0.034
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0167 0.0436
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0111 0.0581
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0018 0.0026
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0007 0.0126
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0025 0.0045 0.0066
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0041
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0111 0.0934
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0154 0.0227
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591
Schistosoma mansoni myosin xvIII 0.0265 0.1349 0.1984
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0051 0.019 0.0994
Loa Loa (eye worm) hypothetical protein 0.0112 0.0521 0.061
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.001
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0007 0.0126
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0265 0.1349 0.3515
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0181 0.0206
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0268 0.0268
Echinococcus multilocularis tumor protein p63 0.0337 0.1739 0.2559
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0326 0.5822
Schistosoma mansoni rab6-interacting 0.0059 0.0231 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Brugia malayi 6-phosphofructokinase 0.0108 0.0499 0.0499
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0044 0.0231
Plasmodium vivax heterochromatin protein 1, putative 0.0023 0.0035 0.1065
Onchocerca volvulus 0.0265 0.1349 0.4155
Brugia malayi hypothetical protein 0.0287 0.1471 0.1471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0042 0.0356
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0111 0.2022
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0013 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0265 0.1349 0.1984
Loa Loa (eye worm) hypothetical protein 0.0609 0.3217 0.3807
Mycobacterium leprae conserved hypothetical protein 0.0019 0.0015 0.0137
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.007 0.0294 0.2462
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0118 0.0174
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.009 0.1504
Echinococcus multilocularis fmrfamide receptor 0.0265 0.1349 0.1984
Onchocerca volvulus 0.0112 0.0521 0.1566
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0018 0.0007 0.0142
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0018 0.0026
Echinococcus granulosus lamin 0.0027 0.0057 0.0149
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0111 0.0164
Schistosoma mansoni hypothetical protein 0.0265 0.1349 0.1984
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0265 0.1349 0.3515
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0499 0.4187
Brugia malayi Dopamine receptor 0.0265 0.1349 0.1349
Brugia malayi hypothetical protein 0.0265 0.1349 0.1349
Echinococcus multilocularis orexin receptor type 2 0.0265 0.1349 0.1984
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0057 0.0057
Echinococcus granulosus zinc finger protein 0.002 0.0017 0.0045
Loa Loa (eye worm) CHromoDomain protein family member 0.0025 0.0045 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0113 0.0166
Echinococcus granulosus lamin dm0 0.0027 0.0057 0.0149
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0044 0.0879
Onchocerca volvulus 0.0265 0.1349 0.4155
Brugia malayi cytochrome P450 0.0018 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0057 0.0475
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0106 0.0156
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0023 0.0035 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0105 0.0878
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.007 0.2154
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0035 0.0291
Leishmania major C-8 sterol isomerase-like protein 0.0367 0.1904 1
Schistosoma mansoni nuclear hormone receptor 0.0287 0.1471 0.2164
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0475 0.398
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0033
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0023 0.0035 0.0051
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0069 0.018
Onchocerca volvulus 0.0027 0.0057 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0042 0.0356
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0111 0.2226
Echinococcus granulosus neuropeptide receptor 0.0265 0.1349 0.3515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0357
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0111 0.029
Mycobacterium ulcerans hypothetical protein 0.0024 0.0044 0.0879
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0609 0.3217 0.4732
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0609 0.3217 0.4732
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0111 0.0585
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0265 0.1349 0.1984
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0609 0.3217 0.4732
Loa Loa (eye worm) hypothetical protein 0.0019 0.0015 0.001
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0106 0.2125
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0015 0.0039
Echinococcus multilocularis peregrin 0.0031 0.0082 0.012
Onchocerca volvulus 0.0265 0.1349 0.4155
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0265 0.1349 0.1349
Echinococcus granulosus G protein coupled receptor 139 0.0265 0.1349 0.3515
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0033
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0057 0.006
Echinococcus multilocularis 0.0018 0.0007 0.001
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0015 0.0022
Loa Loa (eye worm) hypothetical protein 0.0287 0.1471 0.1736
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0104 0.0475 0.398
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0808 0.4299 0.6323
Leishmania major hypothetical protein, conserved 0.0051 0.019 0.1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0495 0.8837
Loa Loa (eye worm) hypothetical protein 0.0265 0.1349 0.1591

Activities

Activity type Activity value Assay description Source Reference
Duration (functional) = 40 min Duration for the antiarrhythmic activity was measured ChEMBL. 7205883
Duration (functional) = 60 min Duration for the sinus rhythm recovery was measured ChEMBL. 7205883
FSC (functional) = 52 % Activity against harris coronary ligation induced ventricular arrhythmia was measured as percent of final sinus complexes after dose 2 mg/kg iv ChEMBL. 7205883
ISC (functional) = 22 % Activity against harris coronary ligation induced ventricular arrhythmia was measured as percent of initial sinus complexes after dose 2 mg/kg iv ChEMBL. 7205883
LD50 (ADMET) = 25 mg kg-1 Toxicity estimated in mouse as LD50 by intravenous administration ChEMBL. 7205883
LD50 (ADMET) = 25 mg kg-1 Toxicity estimated in mouse as LD50 by intravenous administration ChEMBL. 7205883
SRR (functional) = 50 % Activity against ouabain-induced ventricular arrhythmia of the compound was measured as percent of sinus rhythm recovery at dose of 4 mg/kg iv ChEMBL. 7205883

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.