Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2959 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0535 | 0.0721 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0535 | 0.0721 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.724 | 0.9752 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2959 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4163 | 0.4395 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.9228 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.2959 | 0.3986 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.2951 | 0.3975 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.2959 | 0.3753 |
Brugia malayi | hypothetical protein | 0.0035 | 0.2959 | 0.2209 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.3391 | 0.3541 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2959 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.3378 | 0.2673 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.2959 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.9414 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.2959 | 0.3986 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.9414 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0191 | 0.0242 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0535 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.3818 | 0.4014 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.724 | 0.9752 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.2959 | 0.3753 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.7424 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.7424 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.7424 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.7886 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.7424 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.2951 | 0.3975 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.