Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.005 | 0.1778 | 0.824 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0683 | 0.0666 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0407 | 0.182 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0266 | 0.0479 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0133 | 0.5195 | 0.5187 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0007 | 0.0045 | 0.0053 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0683 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 0.5466 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0683 | 0.3115 |
Brugia malayi | TAR-binding protein | 0.0133 | 0.5195 | 0.5187 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0445 | 0.0428 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0007 | 0.0045 | 0.0027 |
Loa Loa (eye worm) | TAR-binding protein | 0.0133 | 0.5195 | 0.5187 |
Onchocerca volvulus | 0.003 | 0.0992 | 0.1509 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0007 | 0.0045 | 0.0053 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0007 | 0.0045 | 0.0027 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0007 | 0.0045 | 0.0053 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0094 | 0.0148 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0683 | 0.0666 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0947 | 0.1795 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | nuclear hormone receptor | 0.0007 | 0.0045 | 0.0053 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0025 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0445 | 0.0428 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0683 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0007 | 0.0045 | 0.0053 |
Loa Loa (eye worm) | RNA binding protein | 0.0133 | 0.5195 | 0.5187 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0683 | 0.0666 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0683 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0992 | 0.0976 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.091 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | thyroid hormone receptor | 0.0007 | 0.0045 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0173 | 0.6835 | 0.6835 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.025 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.025 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.025 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0007 | 0.0045 | 0.0043 |
Onchocerca volvulus | 0.0007 | 0.0045 | 0.0043 | |
Echinococcus multilocularis | lamin | 0.003 | 0.0992 | 0.1881 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.091 | 0.3154 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0007 | 0.0045 | 0.0053 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.005 | 0.1778 | 0.6218 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0266 | 0.0479 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0007 | 0.0045 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0969 | 0.0953 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0992 | 0.0976 |
Toxoplasma gondii | hypothetical protein | 0.0026 | 0.0812 | 0.2805 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0947 | 0.1795 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | lamin | 0.003 | 0.0992 | 0.1881 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0992 | 0.0976 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.2153 | 0.4125 |
Echinococcus multilocularis | musashi | 0.003 | 0.0992 | 0.1881 |
Echinococcus multilocularis | tar DNA binding protein | 0.0133 | 0.5195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0683 | 0.2351 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.2153 | 0.4125 |
Schistosoma mansoni | coup transcription factor | 0.0007 | 0.0045 | 0.0053 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0133 | 0.5195 | 0.5187 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5195 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0007 | 0.0045 | 0.0053 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | lamin | 0.003 | 0.0992 | 0.1881 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0008 | 0.009 | 0.0072 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0007 | 0.0045 | 0.0027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0007 | 0.0045 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0007 | 0.0045 | 0.0053 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0322 | 0.0305 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0007 | 0.0045 | 0.0053 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.091 | 0.4179 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0992 | 0.0976 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0445 | 0.2 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.2153 | 0.7546 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0018 | 0.0018 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0007 | 0.0045 | 0.0027 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0025 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 0.5466 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0683 | 0.2351 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.2153 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.025 | 1 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.2153 | 0.4125 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0007 | 0.0045 | 0.0027 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.2161 | 0.414 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0007 | 0.0045 | 0.0027 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Onchocerca volvulus | 0.0023 | 0.0683 | 0.1031 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0683 | 0.2351 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0322 | 0.0305 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0007 | 0.0045 | 0.0027 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0992 | 0.1881 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0683 | 0.3115 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.005 | 0.1778 | 0.3399 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0882 | 0.0866 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.025 | 1 | 1 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0266 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.091 | 0.0894 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5195 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0164 | 0.6472 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0007 | 0.0045 | 0.0053 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0992 | 0.1881 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | RNA binding protein | 0.0133 | 0.5195 | 0.5187 |
Echinococcus granulosus | lamin | 0.003 | 0.0992 | 0.1881 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0076 | 0.2848 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0015 | 0.0345 | 0.0632 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0445 | 0.0428 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.025 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0947 | 0.1795 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0445 | 0.151 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0018 | 0.0018 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0992 | 0.0976 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0683 | 0.0666 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0094 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0411 | 0.0394 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.091 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0007 | 0.0045 | 0.0027 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.091 | 0.3154 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.091 | 0.3154 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0683 | 0.2351 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0683 | 0.2351 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0683 | 0.2351 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0007 | 0.0045 | 0.0053 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0026 | 0.0812 | 0.2805 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0007 | 0.0045 | 0.0027 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0007 | 0.0045 | 0.0053 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0094 | 0.0077 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0025 | 0.0013 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0007 | 0.0045 | 0.0027 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0076 | 0.2848 | 0.5466 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0007 | 0.0045 | 0.0027 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.2153 | 0.4125 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0007 | 0.0045 | 0.0053 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0496 | 0.0479 |
Brugia malayi | nuclear hormone receptor | 0.0007 | 0.0045 | 0.0027 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0683 | 0.2351 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0007 | 0.0045 | 0.0053 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0173 | 0.6835 | 0.6835 |
Brugia malayi | nuclear receptor NHR-88 | 0.0007 | 0.0045 | 0.0027 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0882 | 0.1669 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0683 | 0.0666 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0407 | 0.182 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0407 | 0.182 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0683 | 0.3115 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0007 | 0.0045 | 0.0027 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.2153 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0411 | 0.0394 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.2153 | 0.7546 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0882 | 0.0866 |
Onchocerca volvulus | 0.0028 | 0.0882 | 0.1339 | |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5195 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.091 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0683 | 0.3115 |
Echinococcus granulosus | FTZ F1 alpha | 0.0007 | 0.0045 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.2848 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.2153 | 0.7546 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.1903 | 0.666 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.005 | 0.1778 | 0.824 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0445 | 0.151 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0683 | 0.2351 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0445 | 0.151 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0025 | 0.0013 |
Schistosoma mansoni | thyroid hormone receptor | 0.0007 | 0.0045 | 0.0053 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.091 | 0.3154 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0445 | 0.0428 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0007 | 0.0045 | 0.0027 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0007 | 0.0045 | 0.0053 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0164 | 0.6472 | 0.6472 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0076 | 0.2848 | 1 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0025 | 0.0013 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0015 | 0.0345 | 0.0632 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | steroid hormone receptor | 0.0007 | 0.0045 | 0.0027 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0407 | 0.182 |
Brugia malayi | Probable ClpP-like protease | 0.0076 | 0.2848 | 0.2835 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.2153 | 0.7546 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0007 | 0.0045 | 0.0053 |
Echinococcus granulosus | tar DNA binding protein | 0.0133 | 0.5195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0345 | 0.0328 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0007 | 0.0045 | 0.0043 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0007 | 0.0045 | 0.0027 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0683 | 0.3115 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0007 | 0.0045 | 0.0027 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0683 | 0.2351 |
Onchocerca volvulus | 0.003 | 0.0992 | 0.1509 | |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0947 | 0.1795 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0007 | 0.0045 | 0.0053 |
Echinococcus granulosus | peptidase Clp S14 family | 0.005 | 0.1778 | 0.3399 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.2848 | 0.2835 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0683 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0683 | 0.2351 |
Brugia malayi | hypothetical protein | 0.0028 | 0.091 | 0.0894 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0007 | 0.0045 | 0.0053 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.025 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0045 | 0.0027 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0007 | 0.0045 | 0.0043 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0007 | 0.0045 | 0.0053 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0007 | 0.0045 | 0.0053 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5195 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0992 | 0.1881 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0445 | 0.0428 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0992 | 0.1881 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0007 | 0.0045 | 0.0027 |
Brugia malayi | ecdysteroid receptor | 0.0007 | 0.0045 | 0.0027 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0026 | 0.0812 | 0.2805 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.2848 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.2848 | 1 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0026 | 0.0812 | 0.2805 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.