Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | para nitrobenzyl esterase | 0.0263 | 0.0292 | 0.0292 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0013 | 0.0008 |
Onchocerca volvulus | 0.0263 | 0.0292 | 0.0624 | |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Echinococcus granulosus | carboxylesterase 5A | 0.1557 | 0.1878 | 0.1878 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.3844 | 0.4681 | 0.4674 |
Onchocerca volvulus | 0.0263 | 0.0292 | 0.0624 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0181 | 0.0192 | 0.0192 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0013 | 0.0008 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0494 | 0.0575 | 0.0575 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0001 | 0.0001 |
Brugia malayi | Carboxylesterase family protein | 0.1557 | 0.1878 | 0.1878 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.1829 | 0.2211 | 0.2301 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0012 | 0.0012 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0005 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.0393 | 0.0393 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0032 | 0.0032 |
Onchocerca volvulus | 0.0035 | 0.0013 | 0.0027 | |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0028 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0032 | 0.0032 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0028 | 0.0005 | 0.0005 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.7852 | 0.9592 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0263 | 0.0292 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0088 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0951 | 0.1136 | 0.1136 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0039 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0013 | 0.0013 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0017 | 0.0017 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.5 |
Echinococcus granulosus | phd:f box containing protein | 0.0028 | 0.0005 | 0.0005 |
Brugia malayi | jmjC domain containing protein | 0.0108 | 0.0102 | 0.0102 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Loa Loa (eye worm) | carboxylesterase | 0.1557 | 0.1878 | 0.1878 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.8185 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0028 | 0.0028 |
Echinococcus granulosus | acetylcholinesterase | 0.1557 | 0.1878 | 0.1878 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0005 | 0.0005 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.7852 | 0.9592 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.7852 | 0.9592 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0122 | 0.0119 | 0.0119 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0108 | 0.0102 | 0.0102 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0287 | 0.0322 | 0.0322 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0106 | 0.01 | 0.01 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0028 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0029 |
Brugia malayi | thymidylate synthase | 0.3844 | 0.4681 | 0.4681 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Echinococcus multilocularis | acetylcholinesterase | 0.1557 | 0.1878 | 0.1878 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0429 | 0.0496 | 0.0484 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.7852 | 0.9592 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0042 | 0.0042 |
Echinococcus multilocularis | dihydrofolate reductase | 0.8185 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1829 | 0.2211 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0263 | 0.0292 | 0.028 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0063 | 0.0063 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0029 |
Echinococcus granulosus | geminin | 0.0345 | 0.0393 | 0.0393 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0223 | 0.0243 | 0.0231 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0028 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | thymidylate synthase | 0.3844 | 0.4681 | 0.4674 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0108 | 0.0102 | 0.0102 |
Brugia malayi | Carboxylesterase family protein | 0.1557 | 0.1878 | 0.1878 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0108 | 0.0102 | 0.0102 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.3844 | 0.4681 | 0.4681 |
Onchocerca volvulus | 0.003 | 0.0007 | 0.0015 | |
Schistosoma mansoni | phd/f-box containing protein | 0.0028 | 0.0005 | 0.0005 |
Echinococcus granulosus | acetylcholinesterase | 0.1557 | 0.1878 | 0.1878 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0028 | 0.0028 |
Echinococcus multilocularis | thymidylate synthase | 0.3844 | 0.4681 | 0.4681 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0088 | 0.0077 | 0.0077 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0028 | 0.0005 | 0.0005 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0017 | 0.0017 |
Brugia malayi | jmjC domain containing protein | 0.0287 | 0.0322 | 0.0322 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.003 | 0.0007 | 0.0007 |
Brugia malayi | Carboxylesterase family protein | 0.0263 | 0.0292 | 0.0292 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0029 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.003 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0013 | 0.0013 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.003 | 0.0007 | 0.0007 |
Onchocerca volvulus | 0.0263 | 0.0292 | 0.0624 | |
Brugia malayi | Bromodomain containing protein | 0.009 | 0.008 | 0.008 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0088 | 0.0077 | 0.0077 |
Onchocerca volvulus | 0.0035 | 0.0013 | 0.0027 | |
Onchocerca volvulus | 0.0242 | 0.0266 | 0.0569 | |
Echinococcus granulosus | thymidylate synthase | 0.3844 | 0.4681 | 0.4681 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0012 | 0.0012 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0263 | 0.0292 | 0.1272 |
Trichomonas vaginalis | set domain proteins, putative | 0.0242 | 0.0266 | 0.1153 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.0005 |
Schistosoma mansoni | protein phosphatase 2C | 0.0028 | 0.0005 | 0.0005 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0013 | 0.0013 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0032 | 0.0009 | 0.0009 |
Brugia malayi | Dihydrofolate reductase | 0.8185 | 1 | 1 |
Chlamydia trachomatis | dihydrofolate reductase | 0.8185 | 1 | 0.5 |
Schistosoma mansoni | dihydrofolate reductase | 0.8185 | 1 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.8185 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0028 | 0.0028 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0005 | 0.0005 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7852 | 0.9592 | 1 |
Echinococcus multilocularis | geminin | 0.0345 | 0.0393 | 0.0393 |
Onchocerca volvulus | 0.0035 | 0.0013 | 0.0027 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0029 |
Brugia malayi | Carboxylesterase family protein | 0.0263 | 0.0292 | 0.0292 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0263 | 0.0292 | 0.0292 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0263 | 0.0292 | 0.028 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0028 | 0.0005 | 0.0005 |
Brugia malayi | hypothetical protein | 0.1829 | 0.2211 | 0.2211 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0108 | 0.0102 | 0.0102 |
Schistosoma mansoni | acetylcholinesterase | 0.0263 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0007 | 0.0007 |
Brugia malayi | follicle stimulating hormone receptor | 0.0494 | 0.0575 | 0.0575 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1557 | 0.1878 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0032 | 0.0032 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0122 | 0.0119 | 0.0119 |
Onchocerca volvulus | Alhambra homolog | 0.0088 | 0.0077 | 0.0165 |
Echinococcus multilocularis | neuroligin | 0.0263 | 0.0292 | 0.0292 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0088 | 0.0077 | 0.0076 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0013 | 0.0013 |
Brugia malayi | PHD-finger family protein | 0.0088 | 0.0077 | 0.0077 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0429 | 0.0496 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0013 | 0.0013 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7852 | 0.9592 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0007 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1557 | 0.1878 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0057 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.1557 | 0.1878 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0013 | 0.0013 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0044 | 0.0044 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0028 | 0.0005 | 0.0005 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0014 | 0.0014 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0879 | 0.1047 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0042 |
Onchocerca volvulus | 0.3844 | 0.4681 | 1 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0028 | 0.0028 |
Echinococcus multilocularis | peregrin | 0.009 | 0.008 | 0.008 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0005 | 0.0005 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0007 | 0.0003 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0263 | 0.0292 | 0.028 |
Loa Loa (eye worm) | carboxylesterase | 0.0263 | 0.0292 | 0.0292 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0287 | 0.0322 | 0.0322 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0013 | 0.0013 |
Brugia malayi | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.8185 | 1 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0013 | 0.0008 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Brugia malayi | AF-10 protein | 0.0029 | 0.0005 | 0.0005 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0429 | 0.0496 | 0.0484 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0263 | 0.0292 | 0.028 |
Echinococcus granulosus | peregrin | 0.009 | 0.008 | 0.008 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0013 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0013 | 0.0008 |
Echinococcus multilocularis | phd:f box containing protein | 0.0028 | 0.0005 | 0.0005 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0013 | 0.0013 |
Mycobacterium tuberculosis | Hypothetical protein | 0.1829 | 0.2211 | 0.2201 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0088 | 0.0077 | 0.0077 |
Echinococcus granulosus | neuroligin | 0.0263 | 0.0292 | 0.0292 |
Onchocerca volvulus | 0.0263 | 0.0292 | 0.0624 | |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0028 | 0.0005 | 0.0005 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0951 | 0.1136 | 0.1136 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Brugia malayi | Carboxylesterase family protein | 0.0263 | 0.0292 | 0.0292 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0028 | 0.0028 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0263 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | thymidylate synthase | 0.3844 | 0.4681 | 0.4681 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0013 | 0.0013 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.0393 | 0.0393 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.3844 | 0.4681 | 0.4674 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0088 | 0.0077 | 0.0076 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Loa Loa (eye worm) | hypothetical protein | 0.1557 | 0.1878 | 0.1878 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0042 | 0.0042 |
Onchocerca volvulus | 0.0263 | 0.0292 | 0.0624 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0088 | 0.0077 | 0.0076 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0013 | 0.0013 |
Echinococcus granulosus | dihydrofolate reductase | 0.8185 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0042 | 0.0039 |
Schistosoma mansoni | gliotactin | 0.0263 | 0.0292 | 0.0292 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0028 | 0.0005 | 0.0005 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0212 | 0.023 | 0.023 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0028 | 0.0005 | 0.0005 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0263 | 0.0292 | 0.1272 |
Schistosoma mansoni | jumonji domain containing protein | 0.0228 | 0.0249 | 0.0249 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0013 | 0.0008 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1557 | 0.1878 | 0.1878 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0007 | 0.0007 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0012 | 0.0012 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0013 | 0.0013 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0013 | 0.0013 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0014 | 0.0014 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0786 | 0.0933 | 0.0933 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0005 | 0.0005 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0088 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0154 | 0.0154 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.8185 | 1 | 1 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0028 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0077 | 0.0077 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0013 | 0.0013 |
Brugia malayi | Carboxylesterase family protein | 0.0263 | 0.0292 | 0.0292 |
Echinococcus multilocularis | acetylcholinesterase | 0.1557 | 0.1878 | 0.1878 |
Brugia malayi | Pre-SET motif family protein | 0.0212 | 0.023 | 0.023 |
Plasmodium falciparum | phd finger protein, putative | 0.0088 | 0.0077 | 0.0076 |
Loa Loa (eye worm) | carboxylesterase | 0.0263 | 0.0292 | 0.0292 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0879 | 0.1047 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0028 | 0.0005 | 0.0005 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0879 | 0.1047 | 0.4704 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.0048 | 0.0048 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0292 | 0.0292 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0263 | 0.0292 | 0.0292 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
-Log IC25 (functional) | = 7.5 | Negative inotropy measured as the concentration required to depress contraction in the isolated Langendorff-perfused guinea pig heart by 25% | ChEMBL. | 2943898 |
-Log IC50 (functional) | = 8.1 | In vitro calcium antagonist activity was assessed against calcium induced constriction of potassium-depolarized rat aorta | ChEMBL. | 2943898 |
Decrease (functional) | = 64.8 % | Percent decrease in coronary vascular resistance in dogs after intravenous dosage of 50 ug/kg compound | ChEMBL. | 2943898 |
Decrease (functional) | = 68.9 % | Percent decrease in coronary vascular resistance in dogs after intravenous dosage of 450 ug/kg compound | ChEMBL. | 2943898 |
Decrease (functional) | = 74.7 % | Percent decrease in coronary vascular resistance in dogs after intravenous dosage of 1500 ug/kg compound | ChEMBL. | 2943898 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.