Detailed information for compound 657250

Basic information

Technical information
  • TDR Targets ID: 657250
  • Name: methyl 6-bromo-5-[(2-fluorophenyl)methoxy]-2- methyl-1-benzofuran-3-carboxylate
  • MW: 393.204 | Formula: C18H14BrFO4
  • H donors: 0 H acceptors: 1 LogP: 4.83 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1c(C)oc2c1cc(OCc1ccccc1F)c(c2)Br
  • InChi: 1S/C18H14BrFO4/c1-10-17(18(21)22-2)12-7-16(13(19)8-15(12)24-10)23-9-11-5-3-4-6-14(11)20/h3-8H,9H2,1-2H3
  • InChiKey: SFSMJFCPDKLOCW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • methyl 6-bromo-5-[(2-fluorophenyl)methoxy]-2-methyl-benzofuran-3-carboxylate
  • 6-bromo-5-[(2-fluorophenyl)methoxy]-2-methyl-3-benzofurancarboxylic acid methyl ester
  • 6-bromo-5-(2-fluorobenzyl)oxy-2-methyl-benzofuran-3-carboxylic acid methyl ester
  • ST5038581
  • ZINC00623663
  • BIM-0003214.P001
  • CBMicro_003483
  • Oprea1_783638

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi TAR-binding protein 0.013 0.2847 0.3945
Schistosoma mansoni cpg binding protein 0.0031 0.0537 0.0537
Schistosoma mansoni ap endonuclease 0.002 0.029 0.029
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0091 0.1943 0.2688
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0493 0.067
Echinococcus multilocularis GPCR, family 2 0.0016 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0966 0.4735
Schistosoma mansoni lamin 0.0029 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0019 0.0269 0.0359
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0072 0.1511 0.7686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0224 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0968 0.4745
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0634 0.2991
Loa Loa (eye worm) RNA binding protein 0.013 0.2847 0.3945
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0061 0.1245 0.6239
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0634 0.2991
Brugia malayi MH2 domain containing protein 0.0119 0.2598 0.3598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.1509 0.7663
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.1943 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.003 0.0534 0.0534
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0943 0.0943
Brugia malayi Muscleblind-like protein 0.0316 0.7199 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0091 0.1943 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.029 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.1077 0.5335
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0534 0.2407
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0013 0.0133 0.0133
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.2598 0.3598
Toxoplasma gondii exonuclease III APE 0.002 0.029 0.1625
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0943 0.0943
Schistosoma mansoni hypothetical protein 0.0013 0.0133 0.0133
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0493 0.067
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0044 0.0045
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0011 0.0087 0.0062
Loa Loa (eye worm) hypothetical protein 0.0316 0.7199 1
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0703 0.3363
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0182 0.0237
Loa Loa (eye worm) hypothetical protein 0.0013 0.0134 0.017
Loa Loa (eye worm) hypothetical protein 0.0013 0.0134 0.017
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0224 0.0295
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0091 0.1943 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.029 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0534 0.2407
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0091 0.1943 0.1943
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0534 0.2455
Schistosoma mansoni hypothetical protein 0.0034 0.0615 0.0615
Schistosoma mansoni lamin 0.0029 0.0493 0.0493
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0043 0.0825 0.4016
Echinococcus multilocularis cpg binding protein 0.0032 0.0578 0.0578
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0091 0.1943 0.1943
Trypanosoma cruzi target of rapamycin kinase 3 0.0072 0.1511 0.7686
Echinococcus granulosus serine protein kinase ATM 0.0017 0.0224 0.0224
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0654 0.0893
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.1338 0.1338
Trichomonas vaginalis rotamase, putative 0.0035 0.0634 0.2947
Loa Loa (eye worm) hypothetical protein 0.0017 0.0224 0.0295
Echinococcus multilocularis tar DNA binding protein 0.013 0.2847 0.2847
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0943 0.0943
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.2598 0.3598
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0534 0.2407
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0634 0.2991
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.029 0.1152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0966 0.4735
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.1176 0.8312
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.1509 0.7663
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0044 0.0044
Giardia lamblia GTOR 0.0091 0.1943 1
Loa Loa (eye worm) phosphatidylinositol 3 0.003 0.0534 0.0726
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0943 0.0943
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0534 0.0726
Schistosoma mansoni tar DNA-binding protein 0.013 0.2847 0.2847
Schistosoma mansoni hypothetical protein 0.0016 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0011 0.0087 0.0105
Echinococcus multilocularis lamin dm0 0.0029 0.0493 0.0493
Schistosoma mansoni cpg binding protein 0.0032 0.0578 0.0578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.1509 0.7663
Echinococcus granulosus intermediate filament protein 0.0029 0.0493 0.0493
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0981 0.1349
Loa Loa (eye worm) hypothetical protein 0.0019 0.0255 0.0338
Loa Loa (eye worm) phosphatidylinositol 3 0.0091 0.1943 0.2688
Schistosoma mansoni tar DNA-binding protein 0.013 0.2847 0.2847
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0534 0.2407
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0091 0.1943 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0981 0.1349
Schistosoma mansoni fkbp-rapamycin associated protein 0.0017 0.0224 0.0224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0224 0.0737
Echinococcus multilocularis serine protein kinase ATM 0.0017 0.0224 0.0224
Echinococcus multilocularis muscleblind protein 1 0.0316 0.7199 0.7199
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.029 0.1152
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.029 0.5
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0224 0.0295
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0012 0.0012
Echinococcus multilocularis muscleblind protein 0.0316 0.7199 0.7199
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0981 0.1349
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0981 0.1349
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.029 0.0388
Echinococcus granulosus GPCR family 2 0.0016 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.109 0.5402
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.029 0.5
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0091 0.1943 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.1509 0.7663
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0493 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.1199 0.5992
Echinococcus granulosus smad 0.0008 0.0012 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Leishmania major phosphatidylinositol 3-related kinase, putative 0.003 0.0534 0.2455
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0654 0.3053
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.029 0.1152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.1943 1
Schistosoma mansoni hypothetical protein 0.0181 0.4039 0.4039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0189 0.0247
Loa Loa (eye worm) hypothetical protein 0.0028 0.0481 0.0653
Schistosoma mansoni tar DNA-binding protein 0.013 0.2847 0.2847
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0091 0.1943 1
Schistosoma mansoni hypothetical protein 0.0016 0.0189 0.0189
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0189 0.0189
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0634 0.2386
Echinococcus multilocularis geminin 0.0181 0.4039 0.4039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0392 0.1641
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0091 0.1943 1
Toxoplasma gondii FATC domain-containing protein 0.0017 0.0224 0.1121
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0146 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0133 0.0247
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.029 0.5
Loa Loa (eye worm) hypothetical protein 0.0013 0.0133 0.0168
Echinococcus multilocularis smad 0.0008 0.0012 0.0012
Brugia malayi intermediate filament protein 0.0029 0.0493 0.067
Schistosoma mansoni ap endonuclease 0.002 0.029 0.029
Echinococcus multilocularis Smad4 0.0008 0.0012 0.0012
Trichomonas vaginalis rotamase, putative 0.0036 0.0654 0.3053
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0017 0.0224 0.0795
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0634 0.2991
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0013 0.0133 0.0133
Echinococcus multilocularis lamin 0.0029 0.0493 0.0493
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0012 0.0012
Echinococcus granulosus tar DNA binding protein 0.013 0.2847 0.2847
Loa Loa (eye worm) hypothetical protein 0.0029 0.0493 0.067
Loa Loa (eye worm) hypothetical protein 0.0014 0.0146 0.0187
Brugia malayi RNA binding protein 0.013 0.2847 0.3945
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0269 0.0984
Echinococcus granulosus lamin 0.0029 0.0493 0.0493
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0943 0.0943
Schistosoma mansoni hypothetical protein 0.0436 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0943 0.0943
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0634 0.4218
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0189 0.0189
Echinococcus multilocularis expressed protein 0.0036 0.0654 0.0654
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0189 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0534 0.2407
Loa Loa (eye worm) hypothetical protein 0.0316 0.7199 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Schistosoma mansoni intermediate filament proteins 0.0029 0.0493 0.0493
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.003 0.0534 0.2455
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0012 0.0012
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0019 0.0269 0.1466
Echinococcus multilocularis dnaJ subfamily B 0.0436 1 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0537 0.0731
Schistosoma mansoni Smad4 0.0008 0.0012 0.0012
Schistosoma mansoni rotamase 0.0036 0.0654 0.0654
Brugia malayi RNA recognition motif domain containing protein 0.013 0.2847 0.3945
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0615 0.0839
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Echinococcus multilocularis musashi 0.0029 0.0493 0.0493
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.003 0.0534 0.0534
Schistosoma mansoni hypothetical protein 0.0016 0.0189 0.0189
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0189 0.0247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.029 0.029
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0943 0.1296
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0189 0.0189
Leishmania major phosphatidylinositol 3-kinase, putative 0.003 0.0534 0.2455
Echinococcus granulosus Smad4 0.0008 0.0012 0.0012
Echinococcus granulosus geminin 0.0181 0.4039 0.4039
Loa Loa (eye worm) TAR-binding protein 0.013 0.2847 0.3945
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0943 0.0943
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0091 0.1943 0.1943
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.003 0.0534 0.0534
Trichomonas vaginalis PIKK family atypical protein kinase 0.0078 0.1633 0.833
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0041 0.0041
Onchocerca volvulus 0.0031 0.0537 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0012 0.0012
Schistosoma mansoni tar DNA-binding protein 0.013 0.2847 0.2847
Schistosoma mansoni smad 0.0008 0.0012 0.0012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0943 0.1296
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0072 0.1511 0.7686
Echinococcus granulosus cpg binding protein 0.0032 0.0578 0.0578
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0012
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.029 0.1152
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0182 0.0237
Echinococcus granulosus muscleblind protein 0.0316 0.7199 0.7199
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0017 0.0224 0.0224
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0189 0.0247
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0012 0.0012
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0654 0.0893
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.029 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0091 0.1943 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0017 0.0224 0.0795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.1943 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0068 0.14 1
Echinococcus granulosus lamin dm0 0.0029 0.0493 0.0493
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.029 0.029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0968 0.4745
Trichomonas vaginalis ap endonuclease, putative 0.002 0.029 0.1097
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0017 0.0224 0.0795
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0966 0.4735
Brugia malayi CXXC zinc finger family protein 0.0031 0.0537 0.0731
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0968 0.4745
Loa Loa (eye worm) hypothetical protein 0.0034 0.0615 0.0839
Schistosoma mansoni smad1 5 8 and 0.0008 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0016 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0968 0.4745
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.14 0.7073
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.2847 0.3945
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0224 0.0737
Trichomonas vaginalis ap endonuclease, putative 0.002 0.029 0.1097
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.029 0.0388
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.003 0.0534 0.2455
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.109 0.5402
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0146 0.0146
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0017 0.0224 0.0224
Schistosoma mansoni tar DNA-binding protein 0.013 0.2847 0.2847
Schistosoma mansoni hypothetical protein 0.0181 0.4039 0.4039
Brugia malayi FAT domain containing protein 0.0013 0.0133 0.0168
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0044 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.109 0.5402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0072 0.1509 0.7663
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.003 0.0534 0.2455
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0017 0.0224 0.0224
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.029 0.0389
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0091 0.1943 1
Echinococcus granulosus expressed protein 0.0036 0.0654 0.0654
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.1077 0.5335
Schistosoma mansoni cpg binding protein 0.0032 0.0578 0.0578

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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