Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0071 | 0.1154 | 0.251 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0071 | 0.1154 | 0.1245 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.0285 | 0.0237 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.0087 | 0.0065 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.1056 | 0.1012 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0027 | 0.0285 | 0.1859 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.0285 | 0.066 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0122 | 0.2146 | 0.2401 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0071 | 0.1154 | 0.1245 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0017 | 0.0087 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1095 | 0.2369 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.0701 | 0.1437 |
Brugia malayi | beta-lactamase | 0.0071 | 0.1154 | 0.2674 |
Schistosoma mansoni | hypothetical protein | 0.0524 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.0285 | 0.0237 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.1154 | 0.1245 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0017 | 0.0087 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.0285 | 0.066 |
Echinococcus granulosus | acetylcholinesterase | 0.0159 | 0.2865 | 0.2806 |
Onchocerca volvulus | 0.0071 | 0.1154 | 1 | |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.0634 | 0.5129 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0071 | 0.1154 | 0.1245 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0071 | 0.1154 | 0.2674 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0122 | 0.2146 | 0.2401 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.014 | 0.25 | 0.2438 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.2865 | 0.6562 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.011 | 0.1906 | 0.2122 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.1277 | 0.2958 |
Echinococcus multilocularis | acetylcholinesterase | 0.0159 | 0.2865 | 0.2806 |
Brugia malayi | glutathione reductase | 0.0048 | 0.0701 | 0.1625 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.1154 | 0.2674 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0218 | 0.0137 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Loa Loa (eye worm) | carboxylesterase | 0.0027 | 0.0285 | 0.0451 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0233 | 0.4316 | 0.4269 |
Onchocerca volvulus | 0.0071 | 0.1154 | 1 | |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0611 | 0.0975 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0332 | 0.0284 |
Leishmania major | trypanothione reductase | 0.0048 | 0.0701 | 0.1133 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0611 | 0.0975 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0027 | 0.0285 | 0.0237 |
Mycobacterium ulcerans | hypothetical protein | 0.0071 | 0.1154 | 0.3734 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.0634 | 0.0556 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.2151 | 0.4983 |
Echinococcus multilocularis | neuroligin | 0.0027 | 0.0285 | 0.0205 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0027 | 0.0285 | 0.0237 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0159 | 0.2865 | 0.2829 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0087 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0484 | 0.0923 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.052 | 0.7057 |
Loa Loa (eye worm) | carboxylesterase | 0.0159 | 0.2865 | 0.6562 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0027 | 0.0285 | 0.0205 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0095 | 0.0046 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.0701 | 0.5758 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0159 | 0.2865 | 0.2806 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0438 | 0.0359 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0027 | 0.0285 | 0.0205 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.0087 | 0.0065 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0027 | 0.0285 | 0.0231 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.04 | 0.0321 |
Schistosoma mansoni | gliotactin | 0.0027 | 0.0285 | 0.0237 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0027 | 0.0285 | 0.1859 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Loa Loa (eye worm) | acetyltransferase | 0.0147 | 0.2624 | 0.5991 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0667 | 0.1355 |
Treponema pallidum | NADH oxidase | 0.0017 | 0.0087 | 0.5 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.031 | 0.5807 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.0701 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.011 | 0.1906 | 0.2122 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.0285 | 0.066 |
Brugia malayi | Carboxylesterase family protein | 0.0159 | 0.2865 | 0.6637 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.0701 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0071 | 0.1154 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0598 | 0.1192 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0044 | 0.0611 | 0.0975 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0027 | 0.0285 | 0.0205 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.0988 | 0.0914 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.0087 | 0.0065 |
Toxoplasma gondii | ABC1 family protein | 0.0071 | 0.1154 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0071 | 0.1154 | 0.3734 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0218 | 0.0137 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.011 | 0.1906 | 0.2122 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.052 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0122 | 0.2146 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0017 | 0.0087 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0233 | 0.4316 | 0.4288 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0071 | 0.1154 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0233 | 0.4316 | 0.4269 |
Brugia malayi | Carboxylesterase family protein | 0.0027 | 0.0285 | 0.066 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1154 | 0.251 |
Echinococcus multilocularis | geminin | 0.0524 | 1 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0071 | 0.1154 | 0.2674 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.0634 | 0.5129 |
Loa Loa (eye worm) | beta-lactamase | 0.0071 | 0.1154 | 0.251 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0147 | 0.2624 | 0.6079 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0439 | 0.0392 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.0634 | 0.5129 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0122 | 0.2146 | 0.2401 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0071 | 0.1154 | 0.1919 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.04 | 0.0321 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.052 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0087 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1154 | 0.251 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Leishmania major | hypothetical protein, conserved | 0.0071 | 0.1154 | 0.1919 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.1154 | 0.1919 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.1154 | 0.1245 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0797 | 0.1298 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0087 | 0.0004 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0071 | 0.1154 | 0.1919 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.0701 | 0.0624 |
Schistosoma mansoni | hypothetical protein | 0.0417 | 0.7898 | 0.7888 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0147 | 0.2622 | 0.4469 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.0701 | 0.1133 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.011 | 0.1906 | 0.7585 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.011 | 0.1906 | 0.2122 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0147 | 0.2624 | 0.2587 |
Mycobacterium tuberculosis | Probable reductase | 0.011 | 0.1906 | 0.2122 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0332 | 0.0769 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0233 | 0.4316 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0439 | 0.1018 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1154 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.0095 | 0.0013 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.0701 | 0.1437 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0233 | 0.4316 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.0701 | 0.0717 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.0701 | 0.5758 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0233 | 0.4316 | 0.4269 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0439 | 0.036 |
Schistosoma mansoni | hypothetical protein | 0.0524 | 1 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0071 | 0.1154 | 0.3734 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.2865 | 0.6562 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.031 | 0.5807 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0159 | 0.2865 | 0.6637 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.1154 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0071 | 0.1154 | 0.3734 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.0701 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.1154 | 0.111 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0233 | 0.4316 | 0.4288 |
Loa Loa (eye worm) | carboxylesterase | 0.0027 | 0.0285 | 0.0451 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.011 | 0.1906 | 0.2122 |
Echinococcus multilocularis | acetylcholinesterase | 0.0159 | 0.2865 | 0.2806 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0027 | 0.0285 | 0.0205 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0071 | 0.1154 | 0.3734 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0071 | 0.1154 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1154 | 0.251 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.2151 | 0.487 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0027 | 0.0285 | 0.0205 |
Echinococcus granulosus | zinc finger protein | 0.0024 | 0.0231 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1154 | 0.251 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.04 | 0.0353 |
Echinococcus granulosus | carboxylesterase 5A | 0.0159 | 0.2865 | 0.2806 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0147 | 0.2622 | 0.4469 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0438 | 0.0359 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0147 | 0.2622 | 0.4469 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0332 | 0.0562 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0071 | 0.1154 | 0.1245 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0285 | 0.066 |
Trichomonas vaginalis | esterase, putative | 0.0071 | 0.1154 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.0634 | 0.5129 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0233 | 0.4316 | 0.4269 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0332 | 0.0769 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0087 | 0.0065 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0095 | 0.0046 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.2151 | 0.487 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0027 | 0.0285 | 0.0231 |
Echinococcus granulosus | neuroligin | 0.0027 | 0.0285 | 0.0205 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0087 | 0.0065 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.0957 | 0.8151 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0016 | 0.0082 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1154 | 0.251 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0071 | 0.1154 | 0.1081 |
Echinococcus multilocularis | zinc finger protein | 0.0024 | 0.0231 | 0.015 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.0634 | 0.5129 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.0701 | 0.5758 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0027 | 0.0285 | 0.0237 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0972 | 0.0928 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0233 | 0.4316 | 0.4288 |
Leishmania major | mitochondrial DNA polymerase beta | 0.031 | 0.5807 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0456 | 0.8664 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0417 | 0.7898 | 0.788 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0417 | 0.7898 | 0.788 |
Schistosoma mansoni | zinc finger protein | 0.0024 | 0.0231 | 0.0183 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0087 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1154 | 1 |
Onchocerca volvulus | 0.0029 | 0.0332 | 0.0539 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0027 | 0.0285 | 0.0694 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0071 | 0.1154 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0071 | 0.1154 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0071 | 0.1154 | 0.111 |
Onchocerca volvulus | 0.0071 | 0.1154 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.0027 | 0.0285 | 0.0237 |
Mycobacterium tuberculosis | Conserved protein | 0.0071 | 0.1154 | 0.1245 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0439 | 0.036 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.031 | 0.5807 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0017 | 0.0087 | 0.0065 |
Mycobacterium ulcerans | hypothetical protein | 0.0163 | 0.2945 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0016 | 0.0082 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.1154 | 0.251 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0736 | 0.6081 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0552 | 0.1279 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0439 | 0.0392 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0218 | 0.017 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.0701 | 0.1133 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0147 | 0.2624 | 0.2563 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.0701 | 0.1625 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0163 | 0.2945 | 0.3333 |
Plasmodium vivax | hypothetical protein, conserved | 0.0071 | 0.1154 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0021 | 0.0163 | 0.0161 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0017 | 0.0087 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0285 | 0.0451 |
Echinococcus granulosus | acetylcholinesterase | 0.0159 | 0.2865 | 0.2806 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0044 | 0.0611 | 0.0975 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.015 | 0.0101 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0027 | 0.0285 | 0.0231 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.0095 | 0.0013 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0159 | 0.2865 | 0.6562 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.015 | 0.013 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0071 | 0.1154 | 0.1081 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0027 | 0.0285 | 0.0205 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.04 | 0.0353 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0087 | 0.0065 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.0988 | 0.0914 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.