Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CAMK family protein kinase | 0.0048 | 0.059 | 0.0287 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.001 | 0.0017 | 0.0015 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0097 | 0.1321 | 1 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0121 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0279 | 0.0588 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.247 | 0.2457 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0032 | 0.0356 | 0.0754 |
Plasmodium vivax | pyruvate kinase, putative | 0.0032 | 0.0356 | 0.0279 |
Loa Loa (eye worm) | DR-78 | 0.001 | 0.0017 | 0.0032 |
Brugia malayi | Muscleblind-like protein | 0.0326 | 0.472 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0311 | 0.0309 |
Onchocerca volvulus | 0.0023 | 0.0222 | 0.1571 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0177 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0066 | 0.0135 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0404 | 0.0339 |
Trypanosoma brucei | pteridine reductase 1 | 0.0039 | 0.0459 | 0.1878 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0404 | 0.0323 |
Mycobacterium ulcerans | pyruvate kinase | 0.0032 | 0.0356 | 0.0265 |
Mycobacterium ulcerans | oxidoreductase | 0.0039 | 0.0459 | 0.0388 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.001 | 0.0017 | 0.0015 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0404 | 0.0339 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0017 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.021 | 0.0441 |
Trypanosoma brucei | polo-like protein kinase | 0.0097 | 0.1321 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0287 | 0.0285 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1348 | 0.1333 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0404 | 0.0853 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.026 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0034 | 0.0068 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0287 | 0.0608 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0134 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0404 | 0.0853 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0175 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0034 | 0.0072 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0175 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.247 | 0.2457 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0177 | 0.0371 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0177 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0066 | 0.0135 |
Loa Loa (eye worm) | pyruvate kinase | 0.0032 | 0.0356 | 0.075 |
Echinococcus multilocularis | pyruvate kinase | 0.0032 | 0.0356 | 0.0354 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0177 | 0.0175 |
Leishmania major | pyruvate kinase | 0.0032 | 0.0356 | 0.1219 |
Echinococcus granulosus | lamin | 0.0028 | 0.0287 | 0.0285 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.001 | 0.002 | 0.0041 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0287 | 0.0271 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0121 | 0.0119 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0177 | 0.0175 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0222 | 0.047 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.1348 | 0.1346 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0404 | 0.1359 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0017 | 0.0035 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0177 | 0.1228 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0097 | 0.1321 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0039 | 0.0459 | 0.0286 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0404 | 0.022 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.001 | 0.0017 | 0.0035 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0404 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0039 | 0.0459 | 0.0403 |
Plasmodium falciparum | pyruvate kinase | 0.0032 | 0.0356 | 0.0279 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0681 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0404 | 0.0339 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0222 | 0.0105 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0097 | 0.1321 | 0.1319 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0404 | 0.0853 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0287 | 0.0605 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0404 | 0.0853 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Onchocerca volvulus | 0.0036 | 0.0404 | 0.297 | |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0017 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0177 | 0.0375 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0222 | 0.0105 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0039 | 0.0459 | 0.2161 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.001 | 0.0017 | 0.0035 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0287 | 0.0608 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0177 | 0.0375 |
Loa Loa (eye worm) | pyruvate kinase | 0.0032 | 0.0356 | 0.075 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0032 | 0.0356 | 0.0162 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0404 | 0.0339 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0032 | 0.0356 | 0.0279 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.001 | 0.0017 | 0.0015 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0287 | 0.0605 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0039 | 0.0459 | 0.2161 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0404 | 0.0337 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0121 | 0.0119 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.1348 | 0.1346 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0177 | 0.0175 |
Leishmania major | oxidoreductase-like protein | 0.0039 | 0.0459 | 0.2161 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0177 | 0.1228 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0177 | 0.0371 |
Onchocerca volvulus | 0.0028 | 0.0287 | 0.2074 | |
Echinococcus multilocularis | pyruvate kinase | 0.0032 | 0.0356 | 0.0354 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0222 | 0.0105 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0039 | 0.0459 | 0.2244 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0177 | 0.016 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0177 | 0.016 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0751 | 0.0735 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0011 | 0.0034 | 0.0068 |
Onchocerca volvulus | 0.0039 | 0.0459 | 0.3392 | |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.472 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0048 | 0.059 | 0.0287 |
Loa Loa (eye worm) | pyruvate kinase | 0.0032 | 0.0356 | 0.075 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0039 | 0.0459 | 0.0403 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0032 | 0.0356 | 0.2599 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.026 | 0.0348 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0404 | 0.1359 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0404 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.028 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0099 | 0.1348 | 0.2856 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0017 | 0.0015 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0404 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0404 | 0.0853 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0404 | 0.0059 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0287 | 0.0271 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0222 | 0.047 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0287 | 0.0285 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0404 | 0.0403 |
Chlamydia trachomatis | pyruvate kinase | 0.0032 | 0.0356 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0034 | 0.0068 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0097 | 0.1321 | 0.1319 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0177 | 0.0175 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.001 | 0.0017 | 0.0015 |
Giardia lamblia | Kinase, PLK | 0.0097 | 0.1321 | 1 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0177 | 0.0375 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0175 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.0034 | 0.0072 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0222 | 0.0106 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0657 | 0.0638 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0177 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0404 | 0.0853 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0097 | 0.1321 | 1 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0287 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0404 | 0.0853 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0222 | 0.0122 |
Brugia malayi | hypothetical protein | 0.001 | 0.0017 | 0.0035 |
Leishmania major | pteridine reductase 1 | 0.0039 | 0.0459 | 0.2161 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0404 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0404 | 0.0853 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1348 | 0.1333 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0017 | 0.0015 |
Onchocerca volvulus | 0.0039 | 0.0459 | 0.3392 | |
Schistosoma mansoni | pyruvate kinase | 0.0017 | 0.0121 | 0.0105 |
Echinococcus granulosus | geminin | 0.0175 | 0.247 | 0.2469 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0177 | 0.016 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0404 | 0.0323 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0177 | 0.0175 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0404 | 0.0059 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0039 | 0.0459 | 0.0404 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0222 | 0.0105 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0039 | 0.0459 | 0.1878 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0404 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0177 | 0.0375 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0032 | 0.0356 | 0.0754 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.001 | 0.0017 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0034 | 0.0068 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0404 | 0.0388 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0177 | 0.0371 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0177 | 0.0375 |
Echinococcus granulosus | pyruvate kinase | 0.0032 | 0.0356 | 0.0354 |
Onchocerca volvulus | 0.0028 | 0.0287 | 0.2071 | |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0177 | 0.016 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0032 | 0.0356 | 0.0281 |
Giardia lamblia | Pyruvate kinase | 0.0032 | 0.0356 | 0.1955 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0034 | 0.0072 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0011 | 0.0034 | 0.0032 |
Brugia malayi | conserved hypotetical protein | 0.001 | 0.0017 | 0.0035 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0311 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0039 | 0.0459 | 0.0458 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0177 | 0.0175 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0177 | 0.0375 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0123 | 0.0261 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0039 | 0.0459 | 0.0404 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0034 | 0.0068 |
Echinococcus granulosus | pyruvate kinase | 0.0032 | 0.0356 | 0.0354 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0582 | 0.8518 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0582 | 0.8518 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Schistosoma mansoni | lamin | 0.0028 | 0.0287 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0073 | 0.0151 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0095 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.028 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0404 | 0.0059 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0404 | 0.0856 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0034 | 0.0017 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0177 | 0.0175 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0039 | 0.0459 | 0.0403 |
Brugia malayi | hypothetical protein | 0.0026 | 0.026 | 0.0551 |
Onchocerca volvulus | 0.002 | 0.0177 | 0.1228 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0222 | 0.0105 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0287 | 0.0608 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0073 | 0.0071 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0097 | 0.1321 | 0.2798 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0121 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.1878 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0047 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0222 | 0.0466 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0404 | 0.0059 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0017 | 0.0035 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0177 | 0.0375 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0404 | 0.0403 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0177 | 0.0375 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0177 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0404 | 0.0856 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0099 | 0.1348 | 0.2853 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0032 | 0.0356 | 0.0903 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0177 | 0.0175 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0404 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0039 | 0.0459 | 0.0973 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0177 | 0.0371 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0039 | 0.0459 | 0.097 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0047 | 0.003 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0177 | 0.0175 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0011 | 0.0034 | 0.0017 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0039 | 0.0459 | 0.0973 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0034 | 0.0068 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0404 | 0.022 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0177 | 0.0371 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0032 | 0.0356 | 0.2599 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0681 | 1 | 1 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0032 | 0.0356 | 0.0903 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0097 | 0.1321 | 0.1306 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0287 | 0.0605 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0039 | 0.0459 | 0.0404 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0039 | 0.0459 | 0.0388 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0177 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0404 | 0.0388 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0047 | 0.0045 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0177 | 0.016 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.001 | 0.0017 | 0.0015 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0177 | 0.0375 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0023 | 0.021 | 0.0441 |
Echinococcus granulosus | muscleblind protein | 0.0326 | 0.472 | 0.4719 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0134 | 0.0017 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0177 | 0.0175 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0404 | 0.0856 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0177 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.472 | 1 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0177 | 0.016 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0073 | 0.0071 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0404 | 0.0323 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0034 | 0.0072 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0177 | 0.1228 |
Schistosoma mansoni | dihydropteridine reductase | 0.0039 | 0.0459 | 0.0443 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0177 | 0.0375 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0177 | 0.0375 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0039 | 0.0459 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0177 | 0.016 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0311 | 0.0295 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0177 | 0.0375 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0097 | 0.1321 | 0.2796 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0404 | 0.166 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0032 | 0.0356 | 0.2599 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0177 | 0.016 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0039 | 0.0459 | 0.0404 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0582 | 0.8518 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0404 | 0.0339 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0177 | 0.0375 |
Schistosoma mansoni | kinase | 0.0049 | 0.0609 | 0.0593 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0404 | 0.0339 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0177 | 0.0175 |
Brugia malayi | tailless protein | 0.001 | 0.0017 | 0.0035 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0039 | 0.0459 | 0.0404 |
Onchocerca volvulus | 0.0036 | 0.0404 | 0.297 | |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0404 | 0.0323 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0134 | 0.0015 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0222 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Loa Loa (eye worm) | oxidoreductase | 0.0039 | 0.0459 | 0.097 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0177 | 0.0375 |
Onchocerca volvulus | 0.0028 | 0.0287 | 0.2071 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0222 | 0.0105 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0404 | 0.0856 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0099 | 0.1348 | 0.1346 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0039 | 0.0459 | 0.0403 |
Echinococcus multilocularis | pyruvate kinase | 0.0026 | 0.0254 | 0.0253 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0097 | 0.1321 | 1 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0039 | 0.0459 | 0.097 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0039 | 0.0459 | 0.0286 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Leishmania major | pyruvate kinase | 0.0032 | 0.0356 | 0.1219 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0177 | 0.0175 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0177 | 0.016 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0177 | 0.0175 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.026 | 0.0165 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0039 | 0.0459 | 0.0458 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0404 | 0.0059 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0404 | 0.0339 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0222 | 0.0105 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0311 | 0.0295 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0287 | 0.0285 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0396 | 0.5763 | 0.5762 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0011 | 0.0034 | 0.0032 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0121 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0177 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0287 | 0.0605 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0177 | 0.0375 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0177 | 0.016 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0582 | 0.8518 | 1 |
Brugia malayi | hypothetical protein | 0.001 | 0.0017 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.028 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.028 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0097 | 0.1321 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0177 | 0.0371 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0287 | 0.0285 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0039 | 0.0459 | 0.0404 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0326 | 0.472 | 0.4719 |
Brugia malayi | ecdysone receptor | 0.001 | 0.0017 | 0.0035 |
Schistosoma mansoni | hypothetical protein | 0.0396 | 0.5763 | 0.5756 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0177 | 0.0375 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0177 | 0.0175 |
Echinococcus granulosus | dnaJ subfamily B | 0.0396 | 0.5763 | 0.5762 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0582 | 0.8518 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0582 | 0.8518 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0099 | 0.1348 | 0.1333 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.026 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0459 | 0.097 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0095 | 0.0198 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.026 | 0.0165 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0034 | 0.0072 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.001 | 0.0017 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0222 | 0.0466 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.001 | 0.0017 | 0.0015 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0177 | 0.016 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0097 | 0.1321 | 0.1183 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.3262 | 0.3742 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.028 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0177 | 0.0375 |
Schistosoma mansoni | lamin | 0.0028 | 0.0287 | 0.0271 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0015 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0039 | 0.0459 | 0.0443 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0015 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0099 | 0.1348 | 0.1346 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0404 | 0.0339 |
Onchocerca volvulus | 0.0036 | 0.0404 | 0.297 | |
Echinococcus multilocularis | geminin | 0.0175 | 0.247 | 0.2469 |
Brugia malayi | Nuclear hormone receptor E75 | 0.001 | 0.0017 | 0.0035 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0032 | 0.0356 | 0.0903 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.001 | 0.0017 | 0.0015 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0039 | 0.0459 | 0.2161 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0222 | 0.0106 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0404 | 0.1359 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.1878 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.026 | 0.0165 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0039 | 0.0459 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.001 | 0.0017 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0356 | 0.075 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0404 | 0.0323 |
Echinococcus multilocularis | muscleblind protein | 0.0326 | 0.472 | 0.4719 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.001 | 0.0017 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0222 | 0.0466 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0582 | 0.8518 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0582 | 0.8518 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0177 | 0.0371 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0032 | 0.0356 | 0.0903 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0121 | 0.0119 |
Schistosoma mansoni | pyruvate kinase | 0.0032 | 0.0356 | 0.034 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0222 | 0.0106 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0039 | 0.0459 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0032 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Brugia malayi | nuclear receptor NHR-67 | 0.001 | 0.0017 | 0.0035 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.001 | 0.0017 | 0.0035 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0039 | 0.0459 | 0.0388 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0222 | 0.0122 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0582 | 0.8518 | 1 |
Schistosoma mansoni | pyruvate kinase | 0.0032 | 0.0356 | 0.034 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.001 | 0.0017 | 0.0032 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0404 | 0.0059 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0222 | 0.047 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0177 | 0.0175 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.