Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | carboxylesterase 5A | 0.1302 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1428 | 0.1428 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Echinococcus multilocularis | geminin | 0.0196 | 0.1237 | 0.1237 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.022 | 0.1428 | 0.1428 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1237 | 0.1237 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.022 | 0.1428 | 0.5 |
Onchocerca volvulus | 0.022 | 0.1428 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Brugia malayi | hypothetical protein | 0.022 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | carboxylesterase | 0.1302 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.022 | 0.1428 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.022 | 0.1428 | 0.1428 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.022 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1428 | 0.1428 |
Echinococcus granulosus | geminin | 0.0196 | 0.1237 | 0.1237 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.022 | 0.1428 | 0.1428 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1302 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.022 | 0.1428 | 0.1428 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.022 | 0.1428 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.022 | 0.1428 | 0.1428 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1302 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.022 | 0.1428 | 0.1428 |
Onchocerca volvulus | 0.022 | 0.1428 | 0.5 | |
Echinococcus granulosus | neuroligin | 0.022 | 0.1428 | 0.1428 |
Onchocerca volvulus | 0.022 | 0.1428 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Echinococcus multilocularis | neuroligin | 0.022 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Echinococcus multilocularis | acetylcholinesterase | 0.1302 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.022 | 0.1428 | 0.0754 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1302 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1302 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1302 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.022 | 0.1428 | 0.1428 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1237 | 0.1237 |
Loa Loa (eye worm) | hypothetical protein | 0.1302 | 1 | 1 |
Onchocerca volvulus | 0.022 | 0.1428 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.022 | 0.1428 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.022 | 0.1428 | 0.1428 |
Echinococcus granulosus | acetylcholinesterase | 0.1302 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.022 | 0.1428 | 0.1428 |
Schistosoma mansoni | acetylcholinesterase | 0.022 | 0.1428 | 0.1428 |
Echinococcus multilocularis | acetylcholinesterase | 0.1302 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.022 | 0.1428 | 0.5 |
Brugia malayi | MH2 domain containing protein | 0.0132 | 0.0729 | 0.0729 |
Brugia malayi | Carboxylesterase family protein | 0.022 | 0.1428 | 0.1428 |
Onchocerca volvulus | 0.022 | 0.1428 | 0.5 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.022 | 0.1428 | 0.1428 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.022 | 0.1428 | 0.1428 |
Loa Loa (eye worm) | hypothetical protein | 0.1302 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.022 | 0.1428 | 0.0754 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.022 | 0.1428 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1428 | 0.0754 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.