Detailed information for compound 658044

Basic information

Technical information
  • TDR Targets ID: 658044
  • Name: 1-(4-tert-butylphenyl)-N-[4-(phenylmethyl)pip erazin-1-yl]methanimine
  • MW: 335.486 | Formula: C22H29N3
  • H donors: 0 H acceptors: 0 LogP: 5.1 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(c1ccc(cc1)C=NN1CCN(CC1)Cc1ccccc1)(C)C
  • InChi: 1S/C22H29N3/c1-22(2,3)21-11-9-19(10-12-21)17-23-25-15-13-24(14-16-25)18-20-7-5-4-6-8-20/h4-12,17H,13-16,18H2,1-3H3/b23-17+
  • InChiKey: RMYIUGFSRSMNJR-HAVVHWLPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(4-tert-butylphenyl)-N-[4-(phenylmethyl)-1-piperazinyl]methanimine
  • [4-(benzyl)piperazin-1-yl]-(4-tert-butylbenzylidene)amine
  • (E)-[4-(benzyl)piperazin-1-yl]-(4-tert-butylbenzylidene)amine
  • 5784-91-8
  • Oprea1_802544
  • STOCK3S-57191
  • CBMicro_033027
  • STK001461
  • BIM-0033152.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0058 0.0055
Leishmania major hypothetical protein, conserved 0.0053 0.0218 0.2794
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0059 0.0248 0.0564
Loa Loa (eye worm) hypothetical protein 0.0066 0.0288 0.0564
Echinococcus multilocularis serotonin receptor 0.0023 0.0058 0.0055
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0047 0.0185 0.2204
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.0998 0.2962
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Loa Loa (eye worm) hypothetical protein 0.0123 0.0592 0.1162
Echinococcus granulosus smad 0.0024 0.0062 0.0059
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0459
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0058 0.0055
Schistosoma mansoni hypothetical protein 0.0016 0.0017 0.0014
Brugia malayi ecdysone receptor 0.0015 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0252
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0097
Schistosoma mansoni tyrosine kinase 0.0512 0.2671 0.267
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0278 0.0276
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0017 0.0214
Loa Loa (eye worm) hypothetical protein 0.0393 0.2032 0.4002
Loa Loa (eye worm) hypothetical protein 0.0037 0.0129 0.0251
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0066 0.0288 0.3693
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.004 0.0092
Schistosoma mansoni glutaminase 0.0836 0.4401 0.44
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0095 0.122
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0095 0.0191
Brugia malayi Doublecortin family protein 0.004 0.0146 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0104 0.023
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0059 0.0248 0.3186
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0095 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.003
Echinococcus multilocularis dna polymerase eta 0.002 0.004 0.0038
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0099 0.0097
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0099 0.127
Brugia malayi Inositol-1 0.0038 0.0135 0.0302
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0113 0.0111
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Onchocerca volvulus 0.0037 0.013 0.0369
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0059 0.0248 0.0485
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0104 0.0101
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0097 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0104 0.0101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0126 0.0124
Brugia malayi Glycosyl hydrolases family 31 protein 0.0713 0.3743 0.8505
Echinococcus granulosus translational activator gcn1 0.0017 0.0024 0.0022
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0017 0.0014
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0014 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0023 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0269 0.0587
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0393 0.2032 0.4002
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0066 0.0288 0.0563
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0058 0.0055
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0058 0.0055
Echinococcus granulosus dna polymerase eta 0.002 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0047 0.0186 0.2385
Brugia malayi ecdysteroid receptor 0.0032 0.0104 0.023
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.0058 0.0055
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0095 0.0236
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0033 0.0065
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.006 0.0058
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0113 0.0111
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0193 0.0545
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0017 0.0014
Onchocerca volvulus 0.0023 0.0058 0.0139
Loa Loa (eye worm) TAR-binding protein 0.0193 0.0967 0.1903
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0126 0.1615
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0023 0.0021
Brugia malayi RNA binding protein 0.0193 0.0967 0.2194
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0117 0.1503
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0091
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Brugia malayi Melatonin receptor type 1A 0.0023 0.0058 0.0126
Brugia malayi jmjC domain containing protein 0.0018 0.0032 0.0067
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0348
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0014 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0031 0.007
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0252
Echinococcus granulosus survival motor neuron protein 1 0.0471 0.2453 0.2451
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0014 0.0011
Schistosoma mansoni amine GPCR 0.0023 0.0058 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0126 0.1615
Loa Loa (eye worm) hypothetical protein 0.0073 0.0323 0.0633
Schistosoma mansoni histamine h1 receptor 0.0023 0.0058 0.0055
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0222 0.1117 0.3319
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0117 0.0302
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0058 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0104 0.023
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.006 0.0776
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.0403 0.0401
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0043 0.0164 0.0348
Brugia malayi hypothetical protein 0.004 0.0146 0.0327
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0286 0.0826
Schistosoma mansoni neuropeptide receptor 0.0023 0.0058 0.0055
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0032 0.0407
Echinococcus multilocularis chromobox protein 1 0.0068 0.0296 0.0294
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.015 0.0148
Echinococcus granulosus neuropeptide s receptor 0.0931 0.4911 0.491
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.013 0.0295
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0058 0.0055
Brugia malayi glutaminase DH11.1 0.0836 0.4401 1
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Schistosoma mansoni smad1 5 8 and 0.0024 0.0062 0.0059
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0017 0.0024 0.0312
Schistosoma mansoni loxhd1 0.004 0.0146 0.0144
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Onchocerca volvulus Huntingtin homolog 0.0393 0.2032 0.6402
Plasmodium falciparum importin beta, putative 0.009 0.0415 0.1197
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.013 0.0356
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0062 0.0059
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0062 0.0117
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0135 0.0307
Schistosoma mansoni amine GPCR 0.0023 0.0058 0.0055
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0014 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.0998 0.2962
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0017 0.0214
Schistosoma mansoni opsin-like receptor 0.0023 0.0058 0.0055
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0014 0.0026
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0288 0.3693
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0186 0.0397
Brugia malayi hypothetical protein 0.0034 0.0117 0.0261
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Brugia malayi TAR-binding protein 0.0193 0.0967 0.2194
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0058 0.0109
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0159 0.0783 0.2316
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0681 0.0679
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0032 0.003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0348
Brugia malayi latrophilin 2 splice variant baaae 0.0424 0.2197 0.499
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0017 0.0014
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0058 0.0055
Schistosoma mansoni smad1 5 8 and 0.0024 0.0062 0.0059
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0104 0.0101
Entamoeba histolytica hypothetical protein 0.0047 0.0185 0.2382
Onchocerca volvulus 0.0096 0.0447 0.1375
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0269 0.0774
Onchocerca volvulus 0.0023 0.0058 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0088 0.0201
Schistosoma mansoni jumonji domain containing protein 0.0149 0.0727 0.0725
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.006 0.0132
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0135 0.1735
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0043 0.0164 0.0162
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0137 0.039
Onchocerca volvulus 0.0076 0.0338 0.1028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0058 0.0055
Leishmania major hypothetical protein, conserved 0.0018 0.0032 0.0407
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Brugia malayi nuclear hormone receptor 0.0015 0.0014 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0269 0.0587
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0017 0.0214
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0117 0.1503
Brugia malayi Calcitonin receptor-like protein seb-1 0.062 0.3245 0.7373
Schistosoma mansoni DNA polymerase eta 0.002 0.004 0.0038
Entamoeba histolytica Ran family GTPase 0.0066 0.0288 0.3693
Onchocerca volvulus 0.0068 0.0298 0.0902
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0347 0.4306
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0043 0.0079
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0058 0.0055
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0218 0.0604
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0017 0.0038
Echinococcus multilocularis microtubule associated protein 2 0.1351 0.7154 0.7153
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0102 0.0196
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0058 0.0055
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0017 0.0038
Echinococcus multilocularis serotonin receptor 0.0023 0.0058 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0158 0.0779 1
Brugia malayi tailless protein 0.0015 0.0014 0.0026
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0159 0.0783 0.2316
Loa Loa (eye worm) beta-lactamase 0.0037 0.013 0.0252
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0032 0.003
Schistosoma mansoni hypothetical protein 0.0196 0.0981 0.0979
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0091
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0214
Leishmania major hypothetical protein, conserved 0.0016 0.0017 0.0214
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0016 0.0017 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0043 0.0164 0.2108
Brugia malayi nuclear receptor NHR-67 0.0015 0.0014 0.0026
Mycobacterium tuberculosis Probable reductase 0.0199 0.0998 0.2962
Loa Loa (eye worm) T-complex protein 1 0.0024 0.006 0.0115
Brugia malayi PHD-finger family protein 0.0057 0.0238 0.0537
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0193 0.0439
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0508 0.6521
Brugia malayi Serotonin receptor 0.0023 0.0058 0.0126
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0099 0.127
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0058 0.0132
Mycobacterium ulcerans beta-lactamase 0.0037 0.013 0.027
Schistosoma mansoni Smad4 0.0024 0.0062 0.0059
Echinococcus multilocularis lysosomal alpha glucosidase 0.0713 0.3743 0.3742
Brugia malayi AKH receptor 0.0023 0.0058 0.0126
Loa Loa (eye worm) jmjC domain-containing protein 0.0118 0.0563 0.1106
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.04 0.5138
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0104 0.0101
Loa Loa (eye worm) TK/FAK protein kinase 0.0518 0.2704 0.5327
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0062 0.0059
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0508 0.0506
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0146 0.0144
Loa Loa (eye worm) hypothetical protein 0.0159 0.0783 0.1539
Schistosoma mansoni opsin-like receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis lysine specific demethylase 5A 0.0069 0.0303 0.03
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0058 0.0055
Mycobacterium tuberculosis Probable oxidoreductase 0.0222 0.1117 0.3319
Echinococcus granulosus X box binding protein 1 0.0283 0.1448 0.1446
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0017 0.0038
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.004 0.0518
Loa Loa (eye worm) hypothetical protein 0.0065 0.0278 0.0545
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0032 0.003
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0058 0.0056
Schistosoma mansoni hypothetical protein 0.0196 0.0981 0.0979
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0088 0.0937
Schistosoma mansoni cytochrome P450 0.0015 0.0011 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0126 0.0286
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0004
Leishmania major cytochrome p450-like protein 0.0015 0.0011 0.0145
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0058 0.0055
Brugia malayi G-protein coupled receptor 0.0023 0.0058 0.0126
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Onchocerca volvulus Alhambra homolog 0.0057 0.0238 0.0713
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0248 0.0564
Loa Loa (eye worm) RNA binding protein 0.0193 0.0967 0.1903
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0135 0.0282
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.004 0.0518
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0104 0.0285
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0058 0.0055
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0193 0.053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Onchocerca volvulus 0.0023 0.0058 0.0139
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0058 0.0055
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.006 0.0776
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.015 0.0148
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0077 0.0175
Echinococcus granulosus g protein coupled receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0424 0.2197 0.4329
Brugia malayi putative neuropeptide receptor 0.0023 0.0058 0.0126
Loa Loa (eye worm) oxidoreductase 0.0043 0.0164 0.0319
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0508 0.6521
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0104 0.023
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0238 0.0681
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0347 0.4451
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0043 0.0164 0.0443
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0196 0.0981 0.2226
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0681 0.0679
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0222 0.1117 0.3319
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.004 0.0038
Trypanosoma brucei unspecified product 0.002 0.004 0.0518
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0126 0.0124
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0043 0.0164 0.0459
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0032 0.0061
Echinococcus granulosus lysosomal alpha glucosidase 0.0713 0.3743 0.3742
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0014 0.0011
Echinococcus granulosus dna polymerase kappa 0.002 0.004 0.0038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0058 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0104 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0104 0.02
Brugia malayi MH1 domain containing protein 0.0013 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0117 0.0266
Echinococcus granulosus tyrosine kinase 0.0037 0.013 0.0128
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0058 0.0055
Onchocerca volvulus 0.0023 0.0058 0.0139
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0104 0.02
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0104 0.0101
Brugia malayi nuclear hormone receptor 0.0032 0.0104 0.023
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0058 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.013 0.0295
Trypanosoma brucei hypothetical protein, conserved 0.0047 0.0185 0.2382
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0088 0.0232
Trichomonas vaginalis hypothetical protein 0.0017 0.0024 0.0055
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0152 0.0345
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0032 0.0407
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0099 0.0097
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0011 0.0018
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.04 0.0785
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0238 0.1206 0.1204
Echinococcus multilocularis smad 0.0024 0.0062 0.0059
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.1191 0.354
Treponema pallidum NADH oxidase 0.003 0.0095 0.1023
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Schistosoma mansoni hypothetical protein 0.0023 0.0058 0.0055
Brugia malayi Glycosyl hydrolases family 31 protein 0.0059 0.0248 0.0559
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Echinococcus granulosus g protein coupled receptor 0.0023 0.0058 0.0055
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0312 0.031
Echinococcus multilocularis geminin 0.1884 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0043 0.0164 0.2108
Brugia malayi GnHR receptor homolog 0.0023 0.0058 0.0126
Brugia malayi Latrophilin receptor protein 2 0.0196 0.0981 0.2226
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0038 0.0137 0.0135
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0248 0.0564
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0269 0.0267
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.04 0.1167
Schistosoma mansoni hypothetical protein 0.0024 0.0061 0.0059
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0508 0.6521
Mycobacterium ulcerans DNA polymerase IV 0.002 0.004 0.0066
Plasmodium vivax glutathione reductase, putative 0.0087 0.04 0.1153
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0058 0.0055
Trichomonas vaginalis maltase-glucoamylase, putative 0.0158 0.0779 0.1769
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0104 0.023
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.0967 0.2194
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0014 0.0011
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Schistosoma mansoni synaptojanin 0.0016 0.0017 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0135 0.1735
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0011 0.0145
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0196 0.0981 0.0979
Plasmodium vivax SET domain protein, putative 0.0065 0.0278 0.0787
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.004 0.0087
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0638 0.3343 1
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0043 0.0164 0.0443
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0218 0.0604
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0099 0.0263
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0058
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0447 0.1011
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0099 0.127
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0014 0.0022
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.013 0.0128
Toxoplasma gondii HEAT repeat-containing protein 0.009 0.0415 0.1211
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0009
Echinococcus multilocularis lamin 0.0079 0.0356 0.0353
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Entamoeba histolytica hypothetical protein 0.0143 0.0696 0.8942
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0104 0.023
Brugia malayi jmjC domain containing protein 0.0071 0.0312 0.0705
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0965
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0031 0.007
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0058 0.0109
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0023 0.0058 0.0126
Brugia malayi Pre-SET motif family protein 0.0065 0.0278 0.0628
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0047 0.0186 0.0397
Loa Loa (eye worm) doublecortin family protein 0.004 0.0146 0.0283
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0099 0.022
Brugia malayi MH1 domain containing protein 0.0024 0.0062 0.0135
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0095 0.122
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0023 0.0021
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0058 0.0055
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.0508 0.6521
Onchocerca volvulus 0.0023 0.0058 0.0139
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.2331 0.233
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0058 0.0055
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0095 0.122
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0058 0.0109
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0014 0.0026
Entamoeba histolytica hypothetical protein 0.0143 0.0696 0.8942
Echinococcus multilocularis short transient receptor potential channel 6 0.013 0.0627 0.0624
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0164 0.0368
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0059 0.0248 0.0744
Schistosoma mansoni ap endonuclease 0.0077 0.0347 0.0344
Plasmodium falciparum glutathione reductase 0.003 0.0095 0.0236
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0104 0.0101
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0098 0.0456 0.0895
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Schistosoma mansoni chromobox protein 0.0068 0.0296 0.0294
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0014 0.0011
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0095 0.0251
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0104 0.0101
Onchocerca volvulus 0.0023 0.0058 0.0139
Schistosoma mansoni jun-related protein 0.0071 0.0311 0.0309
Schistosoma mansoni neuropeptide receptor 0.0023 0.0058 0.0055
Schistosoma mansoni neuropeptide receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis L aminoadipate semialdehyde 0.0168 0.083 0.0828
Loa Loa (eye worm) hypothetical protein 0.0057 0.0238 0.0466
Echinococcus granulosus bloom syndrome protein 0.0023 0.0058 0.0056
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0017 0.0214
Loa Loa (eye worm) latrophilin receptor protein 2 0.0196 0.0981 0.1931
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0459
Schistosoma mansoni polycystin 1-related 0.004 0.0146 0.0144
Loa Loa (eye worm) inositol-1 0.0038 0.0135 0.0262
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0135 0.1735
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0104 0.0101
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0347 0.0775
Brugia malayi hypothetical protein 0.0015 0.0014 0.0026
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0126 0.0124
Leishmania major DNA polymerase kappa, putative 0.002 0.004 0.0518
Brugia malayi jmjC domain containing protein 0.0018 0.0032 0.0067
Mycobacterium ulcerans short chain dehydrogenase 0.0047 0.0186 0.0397
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0014 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.004 0.0518
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0088 0.1136
Onchocerca volvulus 0.0023 0.0058 0.0139
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.006 0.0148
Onchocerca volvulus 0.0605 0.3166 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0099 0.0247
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0508 0.1154
Brugia malayi follicle stimulating hormone receptor 0.0261 0.133 0.3018
Schistosoma mansoni opsin-like receptor 0.0023 0.0058 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Brugia malayi Protein kinase domain containing protein 0.0518 0.2704 0.6141
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0095 0.0093
Loa Loa (eye worm) hypothetical protein 0.0085 0.0385 0.0755
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0347 0.0344
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0171 0.0465
Leishmania major hypothetical protein, conserved 0.0016 0.0017 0.0214
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 0.2133
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0252
Echinococcus granulosus transportin 1 0.0017 0.0024 0.0022
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0042 0.0159 0.031
Schistosoma mansoni hypothetical protein 0.0962 0.5073 0.5072
Brugia malayi Tachykinin-like peptides receptor 99D 0.0023 0.0058 0.0126
Plasmodium falciparum transportin 0.0017 0.0024 0.0023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0347 0.4451
Schistosoma mansoni transcription factor LCR-F1 0.0143 0.0696 0.0694
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis PHD finger protein rhinoceros 0.0057 0.0238 0.0236
Schistosoma mansoni hypothetical protein 0.0196 0.0981 0.0979
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0058 0.0055
Brugia malayi acetyltransferase, GNAT family protein 0.0165 0.0817 0.1851
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0023 0.0058 0.0126
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0029
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0088 0.0232
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0058 0.0055
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0088 0.2176
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0032 0.003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0058 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0218 0.0604
Brugia malayi Dopamine receptor protein 2 0.0023 0.0058 0.0126
Schistosoma mansoni hypothetical protein 0.0023 0.0058 0.0055
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Loa Loa (eye worm) Smad1 0.0024 0.0062 0.0117
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Echinococcus granulosus neuropeptide receptor 0.0023 0.0058 0.0055
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0066 0.0288 0.0649
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0152 0.0345
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.014 0.0681 0.1339
Echinococcus multilocularis lysosomal alpha glucosidase 0.0713 0.3743 0.3742
Brugia malayi hypothetical protein 0.0053 0.0218 0.049
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0095 0.002
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.0508 0.149
Schistosoma mansoni tyrosine kinase 0.0041 0.015 0.0148
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.006 0.0132
Onchocerca volvulus 0.0023 0.0058 0.0139
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0126 0.0124
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0252
Schistosoma mansoni peptidase Clp (S14 family) 0.0159 0.0783 0.0781
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.004 0.0518
Schistosoma mansoni importin-beta 2 0.0017 0.0024 0.0022
Brugia malayi Cytochrome P450 family protein 0.0015 0.0011 0.0021
Echinococcus granulosus chromobox protein 1 0.0068 0.0296 0.0294
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0099 0.0263
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0017 0.0214
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0104 0.02
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0269 0.0587
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0095 0.0251
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.0508 0.0506
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0347 0.0992
Echinococcus granulosus neuropeptide receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.015 0.0148
Schistosoma mansoni microtubule-associated protein tau 0.1351 0.7154 0.7153
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0017 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.013 0.167
Brugia malayi hypothetical protein 0.0605 0.3166 0.7193
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0104 0.0101
Brugia malayi AF-10 protein 0.0019 0.0033 0.007
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0135 0.1735
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0043 0.0164 0.0459
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0017 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0117 0.0266
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0024 0.0039
Toxoplasma gondii thioredoxin reductase 0.0087 0.04 0.1167
Schistosoma mansoni lamin 0.0079 0.0356 0.0353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0137 0.0265
Schistosoma mansoni tyrosine kinase 0.0041 0.015 0.0148
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0126 0.3307
Schistosoma mansoni rab6-interacting 0.004 0.0146 0.0144
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.013 0.0295
Echinococcus granulosus GTP binding nuclear protein Ran 0.0066 0.0288 0.0285
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Schistosoma mansoni hypothetical protein 0.0449 0.2331 0.233
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.004 0.0518
Echinococcus multilocularis musashi 0.0079 0.0356 0.0353
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.013 0.0295
Echinococcus multilocularis peptidase Clp (S14 family) 0.0104 0.049 0.0488
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0095 0.0216
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0032 0.003
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0088 0.0216
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0017 0.0038
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0041 0.0039
Schistosoma mansoni myosin xvIII 0.0023 0.0058 0.0055
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0095 0.122
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0146 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0104 0.02
Echinococcus multilocularis Smad4 0.0024 0.0062 0.0059
Schistosoma mansoni adenoreceptor 0.0023 0.0058 0.0055
Echinococcus granulosus fmrfamide receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0014 0.0011
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0193 0.0545
Echinococcus granulosus L aminoadipate semialdehyde 0.0168 0.083 0.0828
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0104 0.023
Echinococcus multilocularis transportin 1 0.0017 0.0024 0.0022
Echinococcus granulosus orexin receptor type 2 0.0023 0.0058 0.0055
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.004 0.0087
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0033 0.0065
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.0398 0.0396
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0031 0.007
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.004 0.0087
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0057 0.0238 0.0236
Echinococcus multilocularis translational activator gcn1 0.0017 0.0024 0.0022
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0135 0.0307
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0508 0.0997
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0104 0.02
Brugia malayi jmjC domain containing protein 0.0018 0.0032 0.0067
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0104 0.0101
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.0508 0.1131
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0032 0.0058
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.004 0.0518
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0095 0.0191
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.015 0.0148
Echinococcus multilocularis survival motor neuron protein 1 0.0471 0.2453 0.2451
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0348
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Echinococcus granulosus serotonin receptor 0.0023 0.0058 0.0055
Plasmodium vivax transportin, putative 0.0017 0.0024 0.0023
Schistosoma mansoni synaptojanin 0.0016 0.0017 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0104 0.0101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0137 0.0266
Brugia malayi hypothetical protein 0.0143 0.0696 0.1578
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0278 0.0276
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0099 0.0097
Schistosoma mansoni hypothetical protein 0.0096 0.0447 0.0445
Brugia malayi Smad1 0.0024 0.0062 0.0135
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Brugia malayi SRC-1 0.0041 0.015 0.0337
Schistosoma mansoni smad 0.0024 0.0062 0.0059
Trypanosoma brucei glycosyl hydrolase-like protein 0.0059 0.0248 0.3186
Brugia malayi kap beta 3 protein 0.0017 0.0024 0.005
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0011 0.0009
Brugia malayi G-protein coupled receptor 0.0023 0.0058 0.0126
Brugia malayi neuropeptide F receptor 0.0023 0.0058 0.0126
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.0398 0.0396
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Schistosoma mansoni alpha glucosidase 0.0158 0.0779 0.0777
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0296 0.0673
Brugia malayi chromobox protein homolog 3 0.0038 0.0137 0.0305
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0058 0.0055
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0017 0.0038
Loa Loa (eye worm) DR-78 0.0015 0.0014 0.0022
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0043 0.0164 0.0459
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0248 0.0564
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0117 0.0317
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0017 0.0214
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.006 0.0776
Entamoeba histolytica HEAT repeat domain containing protein 0.0017 0.0024 0.0312
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0017 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0058 0.0055
Brugia malayi hypothetical protein 0.0015 0.0014 0.0026
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0278 0.0276
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0017 0.0029
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1619 0.8583 0.8583
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Entamoeba histolytica hypothetical protein 0.0034 0.0117 0.1503
Trichomonas vaginalis set domain proteins, putative 0.0508 0.2646 0.6013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0104 0.023
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.006 0.0132
Leishmania major DNA polymerase eta, putative 0.002 0.004 0.0518
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0043 0.0164 0.0348
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0058 0.0055
Mycobacterium tuberculosis Conserved protein 0.0037 0.013 0.0356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0043 0.0164 0.2108
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 0.2117
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0158 0.0779 0.1769
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0185 0.0523
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0017 0.0214
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0017 0.0014
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.013 0.0356
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0269 0.0267
Onchocerca volvulus 0.0037 0.013 0.0369
Brugia malayi nuclear receptor RXR 0.0017 0.0023 0.0048
Schistosoma mansoni importin beta-1 0.009 0.0415 0.0413
Schistosoma mansoni alpha-glucosidase 0.0614 0.3213 0.3211
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0165 0.0817 0.0815
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0218 0.2794
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Onchocerca volvulus 0.0023 0.0058 0.0139
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0058 0.0055
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.013 0.0356
Chlamydia trachomatis oxoacy-ACP reductase 0.0043 0.0164 0.0233
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0058 0.0055
Giardia lamblia PHD finger protein 15 0.0057 0.0238 0.6719
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.006 0.1327
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0638 0.3343 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0011 0.0145
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.013 0.167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.004 0.0518
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0011 0.0145
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0013 0.003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0061 0.0059
Schistosoma mansoni transient receptor potential channel 0.013 0.0627 0.0624
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0099 0.0191
Loa Loa (eye worm) acetyltransferase 0.0165 0.0817 0.1606
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0017 0.0214
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0347 0.0764
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0058 0.0055
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0088 0.0232
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.008
Loa Loa (eye worm) intermediate filament protein 0.0079 0.0356 0.0697
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0104 0.0101
Entamoeba histolytica hypothetical protein 0.0073 0.0324 0.4156
Schistosoma mansoni hypothetical protein 0.0019 0.0033 0.0031
Echinococcus multilocularis GPCR, family 2 0.0196 0.0981 0.0979
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.0998 0.2962
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Schistosoma mansoni smad1 5 8 and 0.0024 0.0062 0.0059
Brugia malayi MH2 domain containing protein 0.0024 0.0062 0.0135
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0058 0.0055
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0159 0.0783 0.2303
Echinococcus multilocularis chromobox protein 1 0.0068 0.0296 0.0294
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0303 0.0301
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0238 0.1206 0.1204
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.062 0.3245 0.7373
Echinococcus granulosus tar DNA binding protein 0.0193 0.0967 0.0965
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0031 0.007
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0347 0.0783
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0058 0.0055
Trichomonas vaginalis alpha-glucosidase, putative 0.0158 0.0779 0.1769
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0158 0.0779 0.2303
Entamoeba histolytica hypothetical protein 0.0143 0.0696 0.8942
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0058 0.0109
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.011 0.0108
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0029
Brugia malayi ORL1-like opioid receptor 0.0023 0.0058 0.0126
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0117 0.1503
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0052 0.0113
Brugia malayi G protein-coupled receptor 0.0023 0.0058 0.0126
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0058 0.0055
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0143 0.0696 0.0694
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0058 0.0055
Toxoplasma gondii HEAT repeat-containing protein 0.0017 0.0024 0.0039
Leishmania major pantothenate kinase subunit, putative 0.0016 0.0017 0.0214
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0017 0.0024 0.0312
Echinococcus multilocularis synaptojanin 1 0.0016 0.0017 0.0014
Schistosoma mansoni coup transcription factor 0.0032 0.0104 0.0101
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0014 0.0022
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0158 0.0779 0.1769
Trypanosoma brucei oxidoreductase-like protein 0.0047 0.0186 0.2385
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0104 0.0101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Loa Loa (eye worm) hypothetical protein 0.002 0.004 0.0075
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0058 0.0109
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.0403 0.0401
Mycobacterium tuberculosis Probable exported protein 0.0016 0.0017 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.004 0.0038
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Echinococcus granulosus synaptojanin 1 0.0016 0.0017 0.0014
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0104 0.0101
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0058 0.0055
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0126 0.1615
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0011 0.0145
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0017 0.0014
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0347 0.0992
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0014 0.0011
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0348
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0214
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0043 0.0164 0.0162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0681 0.0679
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0171 0.4689
Schistosoma mansoni inositol monophosphatase 0.0038 0.0135 0.0133
Leishmania major pteridine reductase 1 0.0047 0.0186 0.2385
Toxoplasma gondii PHD-finger domain-containing protein 0.0057 0.0238 0.0681
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0023 0.0048
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0017 0.0014
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.015 0.0148
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0043 0.0164 0.0459
Schistosoma mansoni hypothetical protein 0.0023 0.0058 0.0055
Echinococcus granulosus hypothetical protein 0.0023 0.0058 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0031 0.007
Brugia malayi 6-phosphofructokinase 0.0108 0.0508 0.1149
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0104 0.023
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0088 0.0201
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0058 0.0055
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0168 0.083 0.0828
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0047 0.0185 0.0508
Loa Loa (eye worm) hypothetical protein 0.0196 0.0981 0.1931
Brugia malayi beta-lactamase 0.0037 0.013 0.0291
Schistosoma mansoni biogenic amine receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0126 0.0124
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0278 0.0276
Loa Loa (eye worm) hypothetical protein 0.009 0.0415 0.0813
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0152 0.0439
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0104 0.0101
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.0226 0.0629
Schistosoma mansoni nuclear receptor 0.0015 0.0014 0.0011
Schistosoma mansoni cpg binding protein 0.0033 0.0111 0.0109
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0014 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0137 0.031
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Schistosoma mansoni hypothetical protein 0.1884 1 1
Schistosoma mansoni cript-related 0.0016 0.0017 0.0014
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0146 0.0144
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0023 0.0058 0.0139
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0095 0.0251
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0031 0.007
Schistosoma mansoni lipoxygenase 0.0238 0.1206 0.1204
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0066 0.0288 0.0285
Brugia malayi neuropeptide F receptor 0.0023 0.0058 0.0126
Schistosoma mansoni biogenic amine receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0348
Leishmania major GTP-binding protein, putative 0.0066 0.0288 0.3693
Echinococcus granulosus cpg binding protein 0.0033 0.0111 0.0109
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0023 0.0021
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0017 0.0214
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0104 0.0101
Loa Loa (eye worm) SRC-1 0.0041 0.015 0.0292
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0347 0.0344
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0248 0.0564
Leishmania major hypothetical protein, conserved 0.0017 0.0024 0.0312
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.0508 0.0997
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0058 0.0109
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0058 0.0055
Schistosoma mansoni transient receptor potential channel 0.013 0.0627 0.0624
Onchocerca volvulus 0.0032 0.0102 0.0279
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0043 0.0164 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0126 0.0286
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0965
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0032 0.003
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0238 0.0666
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0347 0.4451
Brugia malayi MH2 domain containing protein 0.0352 0.1816 0.4123
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.006 0.0058
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0011 0.0018
Brugia malayi SET domain containing protein 0.0014 0.0009 0.0015
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0104 0.0101
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0104 0.0101
Brugia malayi hypothetical protein 0.004 0.0146 0.0327
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0095 0.0236
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0962 0.5073 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.015 0.0148
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0104 0.0101
Plasmodium falciparum phd finger protein, putative 0.0057 0.0238 0.0666
Echinococcus granulosus short transient receptor potential channel 6 0.013 0.0627 0.0624
Leishmania major hypothetical protein, conserved 0.0016 0.0017 0.0214
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0058
Trichomonas vaginalis esterase, putative 0.0037 0.013 0.0295
Echinococcus granulosus lamin dm0 0.0079 0.0356 0.0353
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0143 0.0696 0.0694
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Onchocerca volvulus 0.0079 0.0356 0.1085
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.013 0.0128
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.006 0.0137
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.0508 0.0506
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.006 0.0776
Onchocerca volvulus 0.004 0.0146 0.042
Loa Loa (eye worm) nuclear factor I 0.0013 0.0004 0.0004
Brugia malayi phosphofructokinase 0.0108 0.0508 0.1149
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Echinococcus granulosus transient receptor potential gamma protein 0.0196 0.0981 0.0979
Schistosoma mansoni rab6-interacting 0.004 0.0146 0.0144
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.013 0.0356
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.0998 0.2962
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0104 0.023
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0218 0.2794
Schistosoma mansoni lamin 0.0079 0.0356 0.0353
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0014 0.0026
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.006 0.0132
Loa Loa (eye worm) kap beta 3 protein 0.0017 0.0024 0.0044
Brugia malayi RNA, U transporter 1 0.0256 0.1302 0.2956
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0348
Echinococcus multilocularis jumonji domain containing protein 0.0079 0.0358 0.0356
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0193 0.0191
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Echinococcus granulosus transient receptor potential ion channel A 0.019 0.0947 0.0945
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trichomonas vaginalis alpha-glucosidase, putative 0.0158 0.0779 0.1769
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0032 0.003
Brugia malayi hypothetical protein 0.0017 0.0023 0.0048
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0099 0.0263
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0104 0.049 0.1437
Loa Loa (eye worm) hypothetical protein 0.003 0.0093 0.0178
Brugia malayi conserved hypotetical protein 0.0015 0.0014 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0029
Echinococcus granulosus importin subunit beta 1 0.009 0.0415 0.0413
Trichomonas vaginalis alpha-glucosidase, putative 0.0059 0.0248 0.0564
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0252
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0032 0.0407
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0095 0.122
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.013 0.0128
Schistosoma mansoni ap endonuclease 0.0077 0.0347 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0104 0.023
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0066 0.0288 0.0814
Brugia malayi Thioredoxin reductase 0.0087 0.04 0.0905
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.015 0.0148
Brugia malayi Cytochrome P450 family protein 0.0034 0.0117 0.0261
Brugia malayi Cytochrome P450 family protein 0.0015 0.0011 0.0021
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trypanosoma brucei unspecified product 0.0014 0.0007 0.0091
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0017 0.0014
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0095 0.0216
Loa Loa (eye worm) hypothetical protein 0.0053 0.0218 0.0425
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.004 0.0092
Echinococcus multilocularis short transient receptor potential channel 6 0.013 0.0627 0.0624
Trichomonas vaginalis glutaminase, putative 0.0836 0.4401 1
Brugia malayi Probable ClpP-like protease 0.0159 0.0783 0.1774
Plasmodium vivax JmjC domain containing protein 0.0018 0.0032 0.0045
Mycobacterium tuberculosis Probable oxidoreductase 0.0047 0.0186 0.0523
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0062 0.0059
Echinococcus multilocularis cpg binding protein 0.0033 0.0111 0.0109
Schistosoma mansoni hypothetical protein 0.0023 0.0058 0.0055
Brugia malayi CXXC zinc finger family protein 0.0032 0.0102 0.0226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0158 0.0779 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.013 0.0295
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0032 0.003
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0017 0.0214
Schistosoma mansoni alpha-glucosidase 0.0614 0.3213 0.3211
Trichomonas vaginalis maltase-glucoamylase, putative 0.0059 0.0248 0.0564
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 0.1757
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0017 0.0214
Brugia malayi MH2 domain containing protein 0.0024 0.0062 0.0135
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0058 0.0055
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0196 0.0981 0.0979
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0226 0.0629
Loa Loa (eye worm) hypothetical protein 0.0043 0.0164 0.0319
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0097
Mycobacterium ulcerans hypothetical protein 0.0037 0.013 0.027
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Loa Loa (eye worm) MH2 domain-containing protein 0.0352 0.1816 0.3577
Brugia malayi Heterochromatin protein 1 0.0068 0.0296 0.0668
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0347 0.4451
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0104 0.023
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.015 0.0148
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0023 0.0058 0.0126
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.0508 0.149
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0146 0.0144
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.013 0.0128
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0095 0.122
Loa Loa (eye worm) hypothetical protein 0.062 0.3245 0.6396
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0508 0.1154
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0043 0.0164 0.0459
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Onchocerca volvulus Neuropeptide F receptor homolog 0.0023 0.0058 0.0139
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0058 0.0132
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0104 0.0101
Brugia malayi putative neuropeptide receptor NPR1 0.0023 0.0058 0.0126
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0312 0.031
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0965
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0088 0.0216
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.015 0.0148
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0032 0.0061
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Schistosoma mansoni dihydropteridine reductase 0.0043 0.0164 0.0162
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Onchocerca volvulus 0.0023 0.0058 0.0139
Mycobacterium ulcerans DNA polymerase IV 0.002 0.004 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0058 0.0055
Brugia malayi beta-lactamase family protein 0.0037 0.013 0.0291
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.013 0.0291
Loa Loa (eye worm) glutathione reductase 0.0087 0.04 0.0785
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0014 0.0011
Loa Loa (eye worm) hypothetical protein 0.0079 0.0356 0.0697
Echinococcus multilocularis protein tyrosine kinase 0.0512 0.2671 0.267
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Loa Loa (eye worm) importin-beta domain-containing protein 0.0017 0.0024 0.0044
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0214
Loa Loa (eye worm) hypothetical protein 0.0118 0.0562 0.1105
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0017 0.0014
Brugia malayi nuclear receptor RXR 0.0015 0.0014 0.0026
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.013 0.0128
Brugia malayi beta-lactamase family protein 0.0037 0.013 0.0291
Schistosoma mansoni lipoxygenase 0.0166 0.0823 0.0821
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0058 0.0055
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0047 0.0185 0.0298
Echinococcus multilocularis neuropeptide receptor A26 0.0931 0.4911 0.491
Trypanosoma brucei unspecified product 0.0014 0.0007 0.0091
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0018 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0278 0.0276
Schistosoma mansoni neuropeptide receptor 0.0023 0.0058 0.0055
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0017 0.0038
Brugia malayi intermediate filament protein 0.0079 0.0356 0.0803
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0017 0.0038
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0036 0.0126 0.0244
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0126 0.0286
Echinococcus granulosus chromobox protein 1 0.0068 0.0296 0.0294
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0047 0.0185 0.0397
Brugia malayi RE15519p 0.0023 0.0058 0.0126
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0058 0.0055
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0214
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0058 0.0055
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0058 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0965
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0058 0.0055
Brugia malayi Serotonin receptor 0.0023 0.0058 0.0126
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0017 0.0214
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0146 0.0389
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0088 0.0201
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0095 0.0236
Mycobacterium leprae Probable lipase LipE 0.0037 0.013 0.0356
Mycobacterium ulcerans oxidoreductase 0.0043 0.0164 0.0348
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0017 0.0214
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.015 0.0148
Schistosoma mansoni hypothetical protein 0.0143 0.0696 0.0694
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.0508 0.6521
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.004 0.0075
Brugia malayi Bromodomain containing protein 0.0061 0.026 0.0586
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0099 0.127
Schistosoma mansoni inositol monophosphatase 0.0038 0.0135 0.0133
Onchocerca volvulus 0.0032 0.0104 0.0285
Loa Loa (eye worm) hypothetical protein 0.0605 0.3166 0.624
Brugia malayi hypothetical protein 0.0393 0.2032 0.4614
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0017 0.0214
Brugia malayi bZIP transcription factor family protein 0.0087 0.0398 0.0899
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus granulosus Smad4 0.0024 0.0062 0.0059
Leishmania major trypanothione reductase 0.0087 0.04 0.5138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0222 0.1117 0.3319
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0104 0.0101
Mycobacterium tuberculosis Conserved protein 0.0037 0.013 0.0356
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0104 0.049 0.1437
Onchocerca volvulus 0.0016 0.0017 0.001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0347 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.0998 0.2962
Brugia malayi 6-phosphofructokinase 0.0108 0.0508 0.1149
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Schistosoma mansoni hypothetical protein 0.0057 0.0238 0.0236
Brugia malayi Cytochrome P450 family protein 0.0015 0.0011 0.0021
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0058 0.0055
Echinococcus granulosus TRP transient receptor potential channel 0.0073 0.0323 0.0321
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0017 0.0214
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.013 0.167
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0058 0.0055
Trichomonas vaginalis ran, putative 0.0066 0.0288 0.0653
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0073 0.0323 0.0321
Trypanosoma brucei trypanothione reductase 0.0087 0.04 0.5138
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0146 0.0144
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0261 0.133 0.2618
Onchocerca volvulus 0.0023 0.0058 0.0139
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0269 0.0267
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.013 0.0356
Onchocerca volvulus 0.0023 0.0058 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0043 0.0164 0.0319
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0324 0.0735
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0017 0.0214
Echinococcus granulosus lamin 0.0079 0.0356 0.0353
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0017 0.0038
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0088 0.0201
Leishmania major hypothetical protein, conserved 0.0037 0.013 0.167
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0058 0.0055
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0058 0.0055
Onchocerca volvulus 0.0023 0.0058 0.0139
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0159 0.0783 0.0781
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0099 0.0097
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0061 0.0059
Leishmania major phosphopantetheinyl transferase-like protein 0.0047 0.0185 0.2382
Echinococcus multilocularis snurportin 1 0.0962 0.5073 0.5072
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0104 0.0285
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.011 0.0108
Leishmania major alpha glucosidase II subunit, putative 0.0158 0.0779 1
Echinococcus multilocularis X box binding protein 1 0.0283 0.1448 0.1446
Brugia malayi CCR4 0.0016 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0164 0.0459
Echinococcus multilocularis 0.0015 0.0011 0.0009
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0159 0.0783 0.0781
Onchocerca volvulus 0.0508 0.2646 0.8351
Echinococcus granulosus microtubule associated protein 2 0.1351 0.7154 0.7153
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0104 0.0101
Schistosoma mansoni hypothetical protein 0.0283 0.1448 0.1446
Echinococcus granulosus phd:f box containing protein 0.0018 0.0032 0.003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0681 0.0679
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0017 0.0214
Entamoeba histolytica hypothetical protein 0.0143 0.0696 0.8942
Echinococcus multilocularis neuropeptide s receptor 0.0931 0.4911 0.491
Loa Loa (eye worm) TK protein kinase 0.0033 0.011 0.0212
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0014 0.0011
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0218 0.2794
Schistosoma mansoni nocturnin 0.0016 0.0017 0.0014
Trichomonas vaginalis chaperonin, putative 0.0024 0.006 0.0137
Schistosoma mansoni transient receptor potential channel 0.0196 0.0981 0.0979
Trypanosoma cruzi hypothetical protein, conserved 0.0158 0.0779 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0135 0.1735
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0214
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.0508 0.6411
Echinococcus granulosus PHD finger protein rhinoceros 0.0057 0.0238 0.0236
Loa Loa (eye worm) cytochrome P450 0.0015 0.0011 0.0018
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0095 0.0093
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0014 0.0011
Schistosoma mansoni hypothetical protein 0.0424 0.2197 0.2196
Echinococcus multilocularis transient receptor potential ion channel A 0.019 0.0947 0.0945
Leishmania major basic transcription factor 3a, putative 0.0034 0.0117 0.1503
Echinococcus granulosus allatostatin A receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis lamin dm0 0.0079 0.0356 0.0353
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.0779 0.1531
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0011 0.0145
Brugia malayi hypothetical protein 0.0023 0.0058 0.0126
Echinococcus multilocularis sex peptide receptor 0.0023 0.0058 0.0055
Brugia malayi jmjC domain containing protein 0.0018 0.0032 0.0067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0164 0.0368
Trichomonas vaginalis alpha-glucosidase, putative 0.0158 0.0779 0.1769
Trichomonas vaginalis alpha-glucosidase, putative 0.0158 0.0779 0.1769
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0043 0.0164 0.0213
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.004 0.0518
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0043 0.0164 0.2108
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0043 0.0164 0.0459
Plasmodium falciparum enoyl-acyl carrier reductase 0.0638 0.3343 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0158 0.0779 0.0777
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0058 0.0055
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0638 0.3343 1
Onchocerca volvulus 0.0047 0.0186 0.0546
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0058 0.0109
Echinococcus granulosus g protein coupled receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.013 0.027
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.015 0.0148
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0058 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0047 0.0185 0.0508
Echinococcus granulosus peregrin 0.0061 0.026 0.0258
Loa Loa (eye worm) transcription factor SMAD2 0.0352 0.1816 0.3577
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Loa Loa (eye worm) hypothetical protein 0.0037 0.013 0.0252
Loa Loa (eye worm) hypothetical protein 0.0168 0.083 0.1633
Echinococcus multilocularis dna polymerase kappa 0.002 0.004 0.0038
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.013 0.0128
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.004 0.0038
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0347 0.1006
Schistosoma mansoni tar DNA-binding protein 0.0193 0.0967 0.0965
Loa Loa (eye worm) hypothetical protein 0.0196 0.0981 0.1931
Toxoplasma gondii ABC1 family protein 0.0037 0.013 0.0356
Schistosoma mansoni chromobox protein 0.0068 0.0296 0.0294
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Brugia malayi larval opioid receptor 0.0023 0.0058 0.0126
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0088 0.0201
Loa Loa (eye worm) hypothetical protein 0.0078 0.0348 0.0681
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0117 0.0227
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0165 0.0817 0.0815
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0114 0.0308
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0347 0.0679
Brugia malayi Transient-receptor-potential like protein 0.0073 0.0323 0.0729
Schistosoma mansoni amine GPCR 0.0023 0.0058 0.0055
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0415 0.5326
Brugia malayi Dopamine receptor 0.0023 0.0058 0.0126
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0104 0.0101
Loa Loa (eye worm) hypothetical protein 0.004 0.0146 0.0283
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0059 0.0248 0.0564
Schistosoma mansoni survival motor neuron protein 0.0096 0.0447 0.0445
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.015 0.0148
Echinococcus granulosus short transient receptor potential channel 6 0.013 0.0627 0.0624
Schistosoma mansoni hypothetical protein 0.1884 1 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0032 0.003
Onchocerca volvulus 0.0023 0.0058 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0095 0.0191
Onchocerca volvulus 0.0023 0.0058 0.0139
Schistosoma mansoni zinc finger protein 0.0015 0.0014 0.0011
Onchocerca volvulus 0.0023 0.0058 0.0139
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0126 0.1615
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.015 0.0148
Echinococcus granulosus histone acetyltransferase KAT2B 0.0161 0.0792 0.079
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0041 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0017 0.0016
Echinococcus granulosus sex peptide receptor 0.0023 0.0058 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0104 0.0101
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0713 0.3743 0.7378
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0043 0.0164 0.0162
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0269 0.0267
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.0508 0.6521
Echinococcus multilocularis jun protein 0.0087 0.0398 0.0396
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 0.2133
Plasmodium falciparum thioredoxin reductase 0.0087 0.04 0.1153
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.013 0.0128
Echinococcus granulosus neuropeptide receptor A26 0.0931 0.4911 0.491
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Leishmania major oxidoreductase-like protein 0.0047 0.0186 0.2385
Onchocerca volvulus 0.0079 0.0356 0.1085
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0031 0.007
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0095 0.0093
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.013 0.0128
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0073 0.0324 0.0735
Loa Loa (eye worm) pigment dispersing factor receptor c 0.062 0.3245 0.6396
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Loa Loa (eye worm) phosphofructokinase 0.0108 0.0508 0.0997
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.0058 0.0055
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0058 0.0055
Brugia malayi Importin beta-1 subunit 0.009 0.0415 0.0938
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0066 0.0288 0.8212
Schistosoma mansoni hypothetical protein 0.0196 0.0981 0.0979
Schistosoma mansoni biogenic amine receptor 0.0023 0.0058 0.0055
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0058 0.0055
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.013 0.027
Brugia malayi sulfakinin receptor protein 0.0023 0.0058 0.0126
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus granulosus jun protein 0.0087 0.0398 0.0396
Echinococcus granulosus importin 5 0.0017 0.0024 0.0022
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0104 0.02
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0043 0.0164 0.0348
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 1
Schistosoma mansoni hypothetical protein 0.0071 0.0311 0.0309
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.0998 0.2962
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0296 0.0579
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 0.2303
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0104 0.0101
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0104 0.0101
Trichomonas vaginalis importin beta-1, putative 0.0073 0.0324 0.0735
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0033 0.0423
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.013 0.0128
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0099 0.0247
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0146 0.0389
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0104 0.02
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0269 0.3456
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0011 0.0145
Schistosoma mansoni ran 0.0066 0.0288 0.0285
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0038 0.0137 0.0135
Trypanosoma brucei importin beta-1 subunit, putative 0.009 0.0415 0.5326
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0011 0.0145
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0087 0.0085
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0126 0.0124
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0062 0.0059
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0032 0.0058
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0226 0.2731
Echinococcus granulosus dnaJ subfamily B 0.0449 0.2331 0.233
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0055 0.0226 0.0644
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0058 0.0127
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0032 0.0058
Brugia malayi isocitrate dehydrogenase 0.0031 0.0099 0.022
Mycobacterium tuberculosis Possible oxidoreductase 0.0043 0.0164 0.0459
Onchocerca volvulus 0.0043 0.0164 0.0478
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0014 0.0011
Echinococcus granulosus GPCR family 2 0.0196 0.0981 0.0979
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Schistosoma mansoni amine GPCR 0.0023 0.0058 0.0055
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.015 0.0148
Loa Loa (eye worm) hypothetical protein 0.0471 0.2453 0.4832
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0066 0.0288 0.0829
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0016 0.0017 0.0014
Loa Loa (eye worm) RecQ helicase 0.0023 0.0058 0.011
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.04 0.1153
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0158 0.0779 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0047 0.0185 0.0397
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0016 0.0017 0.0214
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0638 0.3343 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0137 0.031
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0095 0.122
Giardia lamblia DINP protein human, muc B family 0.002 0.004 0.0718
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.006 0.0058
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.014 0.0681 0.1544
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.014 0.0681 0.0679
Plasmodium vivax hypothetical protein, conserved 0.0037 0.013 0.0341
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0043 0.0164 0.0348
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0032 0.003
Trypanosoma brucei glucosidase, putative 0.0158 0.0779 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.014 0.0681 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0077 0.0175
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Brugia malayi jmjC domain containing protein 0.0187 0.0932 0.2115
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0017 0.0214
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0058 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0088 0.0201
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0058 0.0055
Schistosoma mansoni amine GPCR 0.0023 0.0058 0.0055
Brugia malayi Pre-SET motif family protein 0.0446 0.2318 0.5264
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.015 0.0148
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.004 0.0146 0.0283
Echinococcus granulosus jumonji domain containing protein 0.0079 0.0358 0.0356
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0032 0.003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0017 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0104 0.023
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0347 0.4451
Brugia malayi beta-NAC-like protein 0.0034 0.0117 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0114 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0117 0.0266
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0058 0.0055
Schistosoma mansoni transient receptor potential channel 4 0.0196 0.0981 0.0979
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0347 0.0787
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0058 0.0055
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0095 0.2375
Onchocerca volvulus 0.0016 0.0017 0.001
Brugia malayi hypothetical protein 0.0068 0.0298 0.0672
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0017 0.0029
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.013 0.0252
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0088 0.0216
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0066 0.0288 0.0814
Echinococcus granulosus peptidase Clp S14 family 0.0104 0.049 0.0488
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0269 0.0774
Leishmania major importin beta-1 subunit, putative 0.0073 0.0324 0.4156
Leishmania major cytochrome p450-like protein 0.0015 0.0011 0.0145
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0017 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0011 0.0018
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.013 0.0356
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0023 0.0041
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0052 0.0113
Onchocerca volvulus 0.0168 0.083 0.259
Echinococcus multilocularis RUN 0.004 0.0146 0.0144
Onchocerca volvulus 0.004 0.0146 0.042
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0135 0.0307
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0159 0.0783 0.1757
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0117 0.0226
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0117 0.0302
Trypanosoma cruzi importin beta-1 subunit, putative 0.0073 0.0324 0.4156
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.015 0.0148
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0095 0.122
Echinococcus multilocularis transient receptor potential gamma protein 0.0196 0.0981 0.0979
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.006 0.0058
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0032 0.0045
Echinococcus granulosus protein tyrosine kinase 0.0512 0.2671 0.267
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0099 0.127
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.0967 0.1903
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0062 0.0262 0.026
Brugia malayi cytoplasmic intermediate filament protein 0.0042 0.0159 0.0357
Mycobacterium ulcerans glutaminase 0.0836 0.4401 1
Trypanosoma brucei pteridine reductase 1 0.0043 0.0164 0.2108
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0043 0.0164 0.2108
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0043 0.0164 0.0459
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Brugia malayi nuclear receptor NHR-88 0.0015 0.0014 0.0026
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0312 0.0611
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0126 0.1615
Loa Loa (eye worm) hypothetical protein 0.0037 0.0129 0.0251
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0104 0.0285
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.013 0.0356
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0032 0.003
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0088 0.0216
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0159 0.0783 0.2316
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0014 0.0022
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0043 0.0164 0.0348
Echinococcus granulosus neutral alpha glucosidase AB 0.0158 0.0779 0.0777
Schistosoma mansoni hypothetical protein 0.004 0.0146 0.0144
Brugia malayi MH1 domain containing protein 0.0013 0.0004 0.0004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0126 0.0281
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0017 0.0014
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0288 0.3693
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0043 0.0164 0.0348
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.001 0.0023
Schistosoma mansoni transcription factor btf3 0.0034 0.0117 0.0115
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0146 0.0144
Onchocerca volvulus 0.003 0.0093 0.0251
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0088 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0104 0.023
Schistosoma mansoni ran 0.0066 0.0288 0.0285
Brugia malayi hypothetical protein 0.0471 0.2453 0.5571
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0104 0.023
Plasmodium vivax importin-beta 2, putative 0.009 0.0415 0.1197
Schistosoma mansoni nuclear receptor 0.0015 0.0014 0.0011
Echinococcus granulosus snurportin 1 0.0962 0.5073 0.5072
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0126 0.0124
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Loa Loa (eye worm) PHD-finger family protein 0.0057 0.0238 0.0466
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0446 0.2318 0.4566
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0135 0.0133
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0011 0.0145
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0017 0.0214
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0043 0.0164 0.0348
Mycobacterium tuberculosis Conserved protein 0.0037 0.013 0.0356
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0126 0.0124
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0047 0.0186 0.0397
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0023 0.0058 0.0126
Echinococcus multilocularis transcription factor btf3 0.0034 0.0117 0.0115
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0079 0.0356 0.0697
Echinococcus multilocularis peregrin 0.0061 0.026 0.0258
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0638 0.3343 1
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0058 0.0055
Mycobacterium leprae conserved hypothetical protein 0.0037 0.013 0.0356
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0058 0.0055
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0058 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0031 0.007
Echinococcus multilocularis importin 5 0.0017 0.0024 0.0022
Brugia malayi MH1 domain containing protein 0.0024 0.0062 0.0135
Loa Loa (eye worm) TK protein kinase 0.0037 0.013 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0104 0.023
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0017 0.0029
Brugia malayi hypothetical protein 0.0017 0.0023 0.0048
Schistosoma mansoni cpg binding protein 0.0033 0.0111 0.0109
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0171 0.2201
Trichomonas vaginalis sucrase-isomaltase, putative 0.0158 0.0779 0.1769
Brugia malayi PHD-finger family protein 0.002 0.0043 0.0092
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0095 0.122
Plasmodium falciparum glutathione reductase 0.0087 0.04 0.1153
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.0779 0.1765
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0043 0.0164 0.0459
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0638 0.3343 0.7589
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.004 0.0518
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0278 0.0276
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Onchocerca volvulus 0.0023 0.0058 0.0139
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0043 0.0164 0.2108
Echinococcus multilocularis importin subunit beta 1 0.009 0.0415 0.0413
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0104 0.0101
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0014 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0312 0.031
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0196 0.0981 0.0979
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0135 0.0372
Leishmania major cytochrome p450-like protein 0.0015 0.0011 0.0145
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.014 0.0681 0.0679
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Entamoeba histolytica protein kinase, putative 0.0033 0.011 0.141
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0059 0.0248 0.3186
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0508 0.1154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0058 0.0055
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.006 0.0058
Toxoplasma gondii hypothetical protein 0.0055 0.0226 0.0644
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0104 0.0101
Brugia malayi Dopamine receptor protein 1 0.0023 0.0058 0.0126
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0104 0.0101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.0508 0.1154
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0058 0.0055
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0059 0.0248 0.3186
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0076 0.0338 0.0336
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0135 0.0124
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0023 0.0021
Echinococcus granulosus somatostatin receptor 0.0023 0.0058 0.0055
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0218 0.0619
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0047 0.0185 0.0523
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0023 0.0058 0.0126
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0135 0.0133
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0214
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0017 0.0214
Brugia malayi steroid hormone receptor 0.0032 0.0104 0.023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0014 0.0011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0058 0.0055
Brugia malayi glutathione reductase 0.0087 0.04 0.0905
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0033 0.0423
Brugia malayi Intermediate filament tail domain containing protein 0.0079 0.0356 0.0803
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0017 0.0016
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0196 0.0981 0.0979
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.004 0.0518
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0104 0.049 0.1437
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0014 0.0026
Echinococcus multilocularis tar DNA binding protein 0.0193 0.0967 0.0965
Trichomonas vaginalis hypothetical protein 0.0638 0.3343 0.7596
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0187 0.0932 0.093
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.004 0.0518
Echinococcus granulosus RUN 0.004 0.0146 0.0144
Mycobacterium ulcerans lipase LipD 0.0037 0.013 0.027
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0058 0.0055
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0296 0.0673
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0062 0.0117
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0638 0.3343 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.004 0.0518
Schistosoma mansoni cpg binding protein 0.0032 0.0102 0.0099
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.004 0.0038
Schistosoma mansoni intermediate filament proteins 0.0079 0.0356 0.0353
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0062 0.0059
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0187 0.0932 0.093
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.004 0.0087
Trichomonas vaginalis alpha-glucosidase, putative 0.0158 0.0779 0.1769
Onchocerca volvulus Huntingtin homolog 0.0393 0.2032 0.6402
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0278 0.0802
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0017 0.0029
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0193 0.0439
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0047 0.0186 0.0523
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0022
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0047 0.0185 0.0523
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0347 0.0787
Loa Loa (eye worm) retinol dehydrogenase 12 0.0043 0.0164 0.0319
Brugia malayi G protein-coupled receptor F59B2.13 0.0023 0.0058 0.0126
Echinococcus multilocularis somatostatin receptor 0.0023 0.0058 0.0055
Brugia malayi cytochrome P450 0.0015 0.0011 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0043 0.0164 0.0348
Toxoplasma gondii exonuclease III APE 0.0077 0.0347 0.1006
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0017 0.001
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0095 0.0236
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0047 0.0185 0.0523
Brugia malayi nuclear receptor NHR-88 0.0032 0.0104 0.023
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0017 0.0033
Onchocerca volvulus 0.0412 0.2137 0.6735
Plasmodium falciparum thioredoxin reductase 0.003 0.0095 0.0236
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0117 0.1503
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0058 0.0055
Onchocerca volvulus 0.0037 0.013 0.0369
Brugia malayi protein-tyrosine kinase 0.0037 0.013 0.0291
Loa Loa (eye worm) glutaminase 0.0836 0.4401 0.8674
Leishmania major glycosyl hydrolase-like protein 0.0059 0.0248 0.3186
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0017 0.0214
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.015 0.0148
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0168 0.083 0.1882
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0104 0.023
Echinococcus granulosus transcription factor btf3 0.0034 0.0117 0.0115
Echinococcus granulosus intermediate filament protein 0.0079 0.0356 0.0353
Loa Loa (eye worm) hypothetical protein 0.0032 0.0104 0.02
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0014 0.0011
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0032 0.003
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0017 0.0014
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0047 0.0185 0.0279
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0043 0.0164 0.2108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0095 0.122
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0058 0.0109
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0091
Loa Loa (eye worm) glutaminase 2 0.0836 0.4401 0.8674
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0017 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0104 0.02

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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