Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0264 | 0.0264 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.1337 | 0.5774 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.098 | 0.098 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0031 | 0.0169 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0352 | 0.1518 |
Schistosoma mansoni | hypothetical protein | 0.0869 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.0672 | 0.0672 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0029 | 0.0247 | 0.0247 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0352 | 0.5695 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0029 | 0.0247 | 0.2803 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0672 | 0.0672 |
Echinococcus multilocularis | GPCR, family 2 | 0.0066 | 0.0672 | 0.0672 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0153 | 0.1735 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0363 | 0.1567 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0352 | 0.3989 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0008 | 0.0034 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0029 | 0.0247 | 0.2803 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0153 | 0.435 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0352 | 0.1518 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0352 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0352 | 0.5695 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0153 | 0.1735 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0153 | 0.0153 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0029 | 0.0247 | 0.2803 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0031 | 0.0136 |
Toxoplasma gondii | thioredoxin reductase | 0.0084 | 0.0881 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0352 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0014 | 0.0014 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0199 | 0.2258 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0031 | 0.0169 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0153 | 0.066 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0008 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0352 | 0.3989 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0363 | 1 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0031 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1696 | 0.7321 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0084 | 0.0887 | 0.0887 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0859 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0363 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0352 | 0.1518 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0352 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0352 | 0.1289 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0031 | 0.0136 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.0153 | 0.1735 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0031 | 0.0136 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0207 | 0.2316 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0029 | 0.0247 | 0.2803 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0199 | 0.2258 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.1857 | 0.8018 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0363 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0084 | 0.0881 | 0.3232 |
Plasmodium vivax | glutathione reductase, putative | 0.0084 | 0.0881 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0008 | 0.0034 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0191 | 0.2125 | 0.8958 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0014 | 0.0014 |
Onchocerca volvulus | 0.0038 | 0.0352 | 0.1893 | |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0153 | 0.066 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0031 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0352 | 0.1518 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0142 | 0.1555 | 0.6714 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0153 | 0.0153 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0031 | 0.0031 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0084 | 0.0881 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0029 | 0.0247 | 0.2803 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0352 | 0.3989 |
Leishmania major | trypanothione reductase | 0.0084 | 0.0881 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0363 | 0.0363 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.004 | 0.004 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0153 | 0.0153 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0029 | 0.0247 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0008 | 0.0008 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.098 | 0.098 |
Onchocerca volvulus | 0.0038 | 0.0352 | 0.1893 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0031 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0352 | 0.1518 |
Echinococcus multilocularis | smad | 0.0008 | 0.0008 | 0.0008 |
Brugia malayi | hypothetical protein | 0.0168 | 0.1857 | 0.8018 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0031 | 0.0136 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0031 | 0.0031 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0153 | 0.619 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0199 | 0.2258 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0352 | 0.1289 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0352 | 0.1289 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0031 | 0.0136 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0352 | 0.3989 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0672 | 0.0672 |
Onchocerca volvulus | 0.0029 | 0.0245 | 0.1319 | |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0352 | 0.1518 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0031 | 0.0136 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0191 | 0.2125 | 0.7791 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.0153 | 0.0561 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.0153 | 0.1735 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0031 | 0.0136 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0021 | 0.0158 | 0.0681 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0199 | 0.2258 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0008 | 0.0034 |
Brugia malayi | Smad1 | 0.0008 | 0.0008 | 0.0034 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0029 | 0.0247 | 0.2803 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.0153 | 0.1735 |
Echinococcus multilocularis | dnaJ subfamily B | 0.041 | 0.4671 | 0.4671 |
Schistosoma mansoni | hypothetical protein | 0.041 | 0.4671 | 0.4671 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0199 | 0.2258 |
Onchocerca volvulus | 0.0038 | 0.0352 | 0.1893 | |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0352 | 0.1289 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0031 | 0.0136 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0363 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0008 | 0.0034 |
Brugia malayi | Thioredoxin reductase | 0.0084 | 0.0881 | 0.3806 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0153 | 0.2477 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0031 | 0.0136 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.0672 | 0.0672 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0031 | 0.0136 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0031 | 0.0136 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0029 | 0.0247 | 0.2803 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0029 | 0.0247 | 0.0247 |
Echinococcus multilocularis | muscleblind protein | 0.0154 | 0.1696 | 0.1696 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0029 | 0.0247 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0029 | 0.0247 | 0.2803 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0066 | 0.0672 | 0.2901 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0191 | 0.2125 | 0.7791 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0617 | 0.2264 |
Trypanosoma brucei | trypanothione reductase | 0.0084 | 0.0881 | 1 |
Brugia malayi | glutathione reductase | 0.0084 | 0.0881 | 0.3806 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0029 | 0.0247 | 0.1067 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0029 | 0.0247 | 0.0906 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.004 | 0.004 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.004 | 0.004 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0029 | 0.0247 | 0.4002 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0363 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0264 | 0.0264 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0352 | 0.1518 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0084 | 0.0881 | 0.3806 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0029 | 0.0247 | 1 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0008 | 0.0008 |
Plasmodium falciparum | thioredoxin reductase | 0.0084 | 0.0881 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.1337 | 0.5774 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0084 | 0.0887 | 0.0887 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.1555 | 0.1555 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0029 | 0.0247 | 0.7028 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0352 | 0.5695 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0352 | 0.1289 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0264 | 0.0264 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0153 | 0.435 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0031 | 0.0136 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.062 | 0.062 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0191 | 0.2125 | 0.7791 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0031 | 0.0136 |
Plasmodium falciparum | glutathione reductase | 0.0029 | 0.0247 | 0.2803 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Probable reductase | 0.0191 | 0.2125 | 0.7791 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0031 | 0.0169 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0363 | 0.0363 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0544 | 0.6171 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0352 | 0.0352 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0031 | 0.0136 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0352 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0031 | 0.0136 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0352 | 0.0352 |
Treponema pallidum | NADH oxidase | 0.0029 | 0.0247 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0084 | 0.0881 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0031 | 0.0031 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0243 | 0.2728 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0352 | 0.3989 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0199 | 0.2258 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0029 | 0.0247 | 0.4002 |
Schistosoma mansoni | smad | 0.0008 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.1337 | 0.5774 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.0153 | 0.619 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0352 | 0.1518 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0031 | 0.0031 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0153 | 0.619 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.098 | 0.098 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0617 | 0.0617 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0031 | 0.0031 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0352 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0029 | 0.0247 | 0.2803 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0352 | 0.1482 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0352 | 0.1518 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0008 | 0.0008 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0352 | 0.1518 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0245 | 0.1058 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0031 | 0.0136 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0352 | 0.1289 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.1555 | 0.6714 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0352 | 0.1289 |
Plasmodium falciparum | thioredoxin reductase | 0.0029 | 0.0247 | 0.2803 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0008 | 0.0034 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0029 | 0.0247 | 0.2803 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0352 | 0.1518 |
Brugia malayi | Muscleblind-like protein | 0.0154 | 0.1696 | 0.7321 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0031 | 0.0136 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0352 | 0.1289 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.098 | 0.098 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0153 | 0.1735 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Echinococcus multilocularis | geminin | 0.0869 | 1 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0245 | 0.1058 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0008 | 0.0008 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0245 | 0.0245 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0352 | 0.0352 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0031 | 0.0136 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0617 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0066 | 0.0672 | 0.2901 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0031 | 0.0031 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.098 | 0.098 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0352 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0672 | 0.2901 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0013 | 0.0055 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0029 | 0.0247 | 0.2803 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0008 | 0.0008 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0617 | 0.0617 |
Echinococcus granulosus | smad | 0.0008 | 0.0008 | 0.0008 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0092 | 0.098 | 0.4233 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0191 | 0.2125 | 0.7791 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0031 | 0.0031 |
Onchocerca volvulus | 0.001 | 0.0031 | 0.0169 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0031 | 0.0031 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0029 | 0.0247 | 0.7028 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0031 | 0.0031 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0352 | 0.1482 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0199 | 0.2258 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0617 | 0.0617 |
Onchocerca volvulus | 0.0168 | 0.1857 | 1 | |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0029 | 0.0247 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0352 | 0.5695 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1696 | 0.7321 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.0672 | 0.0672 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0021 | 0.0153 | 0.4215 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0199 | 0.2258 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0029 | 0.0247 | 0.2803 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0212 | 0.2372 | 0.8697 |
Echinococcus granulosus | FTZ F1 alpha | 0.0406 | 0.4627 | 0.4627 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0191 | 0.2125 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0352 | 0.1518 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0029 | 0.0247 | 0.2803 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0031 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0672 | 0.0672 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0352 | 0.3989 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0031 | 0.0031 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0264 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0029 | 0.0247 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0212 | 0.2372 | 0.8697 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0617 | 0.7004 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0352 | 0.0352 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0617 | 0.7004 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0363 | 0.0363 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0031 | 0.0031 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0092 | 0.098 | 0.4233 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0031 | 0.0136 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0014 | 0.0061 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0008 | 0.0034 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0031 | 0.0136 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.0672 | 0.0672 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0199 | 0.0859 |
Echinococcus granulosus | GPCR family 2 | 0.0066 | 0.0672 | 0.0672 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0617 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0031 | 0.0136 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0084 | 0.0881 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0352 | 0.5695 |
Echinococcus granulosus | muscleblind protein | 0.0154 | 0.1696 | 0.1696 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0031 | 0.0136 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0008 | 0.0008 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0153 | 0.0153 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0207 | 0.2316 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.0153 | 0.1735 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0021 | 0.0158 | 0.0681 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0031 | 0.0031 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0029 | 0.0247 | 0.2803 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.098 | 0.098 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0029 | 0.0247 | 0.4002 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0066 | 0.0672 | 0.2901 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0097 | 0.0418 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.098 | 0.098 |
Loa Loa (eye worm) | glutathione reductase | 0.0084 | 0.0881 | 0.3806 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0352 | 0.1289 |
Echinococcus granulosus | dnaJ subfamily B | 0.041 | 0.4671 | 0.4671 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0031 | 0.0136 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0617 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0617 | 0.0617 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0154 | 0.1696 | 0.1696 |
Schistosoma mansoni | hypothetical protein | 0.0869 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0212 | 0.2372 | 0.8697 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.2316 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0031 | 0.0136 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0031 | 0.0136 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0212 | 0.2372 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0207 | 0.2316 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0352 | 0.1289 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0672 | 0.0672 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.