Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | TAR-binding protein | 0.0124 | 0.4521 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.3049 | 0.6686 |
Loa Loa (eye worm) | RNA binding protein | 0.0124 | 0.4521 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0124 | 0.4521 | 0.4928 |
Schistosoma mansoni | P2X receptor subunit | 0.0069 | 0.1555 | 0.171 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0265 | 0.0205 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0124 | 0.4521 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0265 | 0.0415 |
Schistosoma mansoni | P2X receptor subunit | 0.0069 | 0.1555 | 0.171 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0138 | 0.5281 | 0.5772 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0097 | 0.3049 | 0.6686 |
Schistosoma mansoni | P2X receptor subunit | 0.0209 | 0.9091 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0124 | 0.4521 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0265 | 0.0205 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0265 | 0.0291 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0209 | 0.9091 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0209 | 0.9091 | 1 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.008 | 0.0089 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0209 | 0.9091 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0209 | 0.9091 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0209 | 0.9091 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0209 | 0.9091 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0265 | 0.0205 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0138 | 0.5281 | 0.5772 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.2734 | 0.2945 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.2734 | 0.2945 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4521 | 0.4973 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.313 | 0.3443 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0583 | 0.1131 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0265 | 0.0205 |
Brugia malayi | TAR-binding protein | 0.0124 | 0.4521 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4521 | 0.4973 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0097 | 0.3049 | 0.3295 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0097 | 0.3049 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0124 | 0.4521 | 0.4928 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4521 | 0.4973 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4521 | 0.4973 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0396 | 0.035 |
Schistosoma mansoni | tar DNA-binding protein | 0.0124 | 0.4521 | 0.4973 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0265 | 0.0291 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.008 | 0.5 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0097 | 0.3049 | 0.3295 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0265 | 0.0415 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0265 | 0.0291 |
Brugia malayi | RNA binding protein | 0.0124 | 0.4521 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0209 | 0.9091 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.