Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.037 | 0.0366 | 0.1002 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0455 | 0.049 | 0.049 |
Onchocerca volvulus | 0.0153 | 0.0049 | 0.0041 | |
Echinococcus granulosus | histone deacetylase 6 | 0.0455 | 0.049 | 0.049 |
Giardia lamblia | Kinase, CMGC CDK | 0.0225 | 0.0154 | 0.2692 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0225 | 0.0154 | 0.0152 |
Trypanosoma brucei | histone deacetylase, putative | 0.0455 | 0.049 | 0.1345 |
Loa Loa (eye worm) | hypothetical protein | 0.05 | 0.0557 | 0.0555 |
Echinococcus multilocularis | neuroglian | 0.0475 | 0.0519 | 0.0519 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0225 | 0.0154 | 0.0413 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.2589 | 0.3608 | 0.3608 |
Brugia malayi | ephrin receptor 1 precursor | 0.0194 | 0.0109 | 0.0107 |
Echinococcus multilocularis | hemicentin 1 | 0.0225 | 0.0154 | 0.0154 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0226 | 0.0156 | 0.0156 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.2589 | 0.3608 | 1 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0363 | 0.0356 | 0.0354 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0225 | 0.0154 | 0.0152 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.0121 | 0.0002 | 0.0002 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0225 | 0.0154 | 0.0154 |
Echinococcus multilocularis | leucine rich repeat containing protein 4 | 0.0121 | 0.0002 | 0.0002 |
Schistosoma mansoni | tyrosine kinase | 0.0179 | 0.0087 | 0.0085 |
Schistosoma mansoni | vesicular amine transporter | 0.038 | 0.038 | 0.0378 |
Plasmodium falciparum | protein kinase 5 | 0.0225 | 0.0154 | 0.2692 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.038 | 0.038 | 0.0378 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0142 | 0.0033 | 0.0031 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0455 | 0.049 | 0.0488 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0302 | 0.0267 | 0.0267 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus granulosus | neuroglian | 0.0226 | 0.0156 | 0.0156 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Echinococcus granulosus | pro neuregulin 2 membrane bound | 0.0121 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0226 | 0.0156 | 0.0153 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.038 | 0.038 | 0.0378 |
Schistosoma mansoni | titin | 0.0225 | 0.0154 | 0.0152 |
Echinococcus granulosus | roundabout 2 | 0.0605 | 0.071 | 0.071 |
Brugia malayi | histone deacetylase 11 | 0.0235 | 0.017 | 0.0168 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0225 | 0.0154 | 0.0413 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0123 | 0.0005 | 0.0005 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0225 | 0.0154 | 0.0413 |
Brugia malayi | Protein kinase domain containing protein | 0.0252 | 0.0194 | 0.0192 |
Schistosoma mansoni | serine/threonine protein kinase | 0.037 | 0.0366 | 0.0364 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0269 | 0.0218 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.1046 | 0.1353 | 0.1353 |
Echinococcus multilocularis | cell adhesion molecule:down regulated by | 0.0121 | 0.0002 | 0.0002 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0412 | 0.0428 | 0.0428 |
Onchocerca volvulus | 0.4341 | 0.6167 | 0.9504 | |
Echinococcus granulosus | hemicentin 1 | 0.0225 | 0.0154 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0501 | 0.0557 | 0.0555 |
Echinococcus multilocularis | ephrin type A receptor 4 A | 0.0321 | 0.0294 | 0.0294 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0225 | 0.0154 | 0.2692 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Brugia malayi | protein-tyrosine kinase | 0.0269 | 0.0218 | 0.0216 |
Schistosoma mansoni | septate junction protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0121 | 0.0002 | 0.0002 |
Echinococcus granulosus | defective proboscis extension response | 0.038 | 0.038 | 0.038 |
Echinococcus granulosus | insulin receptor | 0.2393 | 0.3321 | 0.3321 |
Brugia malayi | Peroxidasin | 0.0216 | 0.0141 | 0.0139 |
Echinococcus granulosus | activin receptor type | 0.0123 | 0.0005 | 0.0005 |
Plasmodium vivax | protein kinase, putative | 0.0129 | 0.0014 | 0.016 |
Entamoeba histolytica | protein kinase, putative | 0.037 | 0.0366 | 0.6534 |
Schistosoma mansoni | tyrosine kinase | 0.0412 | 0.0428 | 0.0426 |
Echinococcus granulosus | peroxidasin | 0.0216 | 0.0141 | 0.0141 |
Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.2202 | 0.3043 | 0.3043 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0216 | 0.0141 | 0.0139 |
Brugia malayi | SH2 domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Brugia malayi | Histone deacetylase family protein | 0.0455 | 0.049 | 0.0488 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0153 | 0.0049 | 0.0049 |
Echinococcus multilocularis | dual specificity testis specific protein kinase | 0.0123 | 0.0005 | 0.0005 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0226 | 0.0156 | 0.0153 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0123 | 0.0005 | 0.0003 |
Schistosoma mansoni | roundabout | 0.0216 | 0.0141 | 0.0139 |
Echinococcus granulosus | Immunoglobulin | 0.038 | 0.038 | 0.038 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.037 | 0.0366 | 0.1002 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0049 | 0.0047 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0501 | 0.0558 | 0.0558 |
Echinococcus multilocularis | peroxidasin | 0.0216 | 0.0141 | 0.0141 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0131 | 0.0017 | 0.0017 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0295 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0217 | 0.0143 | 0.0141 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0501 | 0.0558 | 0.1533 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0153 | 0.0049 | 0.0794 |
Echinococcus granulosus | histone deacetylase 6 | 0.0455 | 0.049 | 0.049 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0963 | 0.1232 | 0.3406 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0225 | 0.0154 | 0.0154 |
Brugia malayi | Protein kinase domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Echinococcus granulosus | dual specificity testis-specific protein kinase | 0.0123 | 0.0005 | 0.0005 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0225 | 0.0154 | 0.0152 |
Schistosoma mansoni | histone deacetylase | 0.0501 | 0.0558 | 0.0555 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0501 | 0.0558 | 0.0555 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0455 | 0.049 | 0.0488 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Onchocerca volvulus | 0.0153 | 0.0049 | 0.0041 | |
Echinococcus granulosus | Immunoglobulin | 0.0121 | 0.0002 | 0.0002 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0295 | 0.0256 | 0.0256 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0295 | 0.0256 | 0.0256 |
Echinococcus multilocularis | lachesin | 0.0216 | 0.0141 | 0.0141 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0252 | 0.0194 | 0.0525 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0963 | 0.1232 | 0.3406 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0412 | 0.0428 | 0.0428 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.6965 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0295 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0131 | 0.0017 | 0.0015 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0501 | 0.0558 | 1 |
Echinococcus granulosus | histone deacetylase 8 | 0.0235 | 0.017 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.038 | 0.0378 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.0356 | 0.0354 |
Toxoplasma gondii | fructose-bisphospatase II | 0.2589 | 0.3608 | 1 |
Brugia malayi | hypothetical protein | 0.0153 | 0.0049 | 0.0047 |
Schistosoma mansoni | tyrosine kinase | 0.2393 | 0.3321 | 0.332 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0501 | 0.0558 | 0.1533 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0252 | 0.0194 | 0.0525 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0123 | 0.0005 | 0.0003 |
Echinococcus multilocularis | pro neuregulin 2, membrane bound | 0.0121 | 0.0002 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0134 | 0.0022 | 0.002 |
Entamoeba histolytica | hypothetical protein | 0.037 | 0.0366 | 0.6534 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0455 | 0.049 | 0.049 |
Echinococcus multilocularis | neuroglian | 0.0226 | 0.0156 | 0.0156 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.0004 | 0.0002 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0235 | 0.017 | 0.0457 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0131 | 0.0017 | 0.0015 |
Echinococcus multilocularis | roundabout 2 | 0.0226 | 0.0156 | 0.0156 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0179 | 0.0087 | 0.0085 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0216 | 0.0141 | 0.0141 |
Onchocerca volvulus | 0.0153 | 0.0049 | 0.0041 | |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0225 | 0.0154 | 0.0154 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.2589 | 0.3608 | 1 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.1046 | 0.1353 | 0.1351 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0483 | 0.0532 | 0.5 |
Schistosoma mansoni | cell adhesion molecule | 0.0226 | 0.0156 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0501 | 0.0558 | 0.0555 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Schistosoma mansoni | tyrosine kinase | 0.0153 | 0.0049 | 0.0047 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0226 | 0.0156 | 0.0156 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0501 | 0.0558 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Echinococcus granulosus | histone deacetylase | 0.0455 | 0.049 | 0.049 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0295 | 0.0256 | 0.0256 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0123 | 0.0005 | 0.0002 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0225 | 0.0154 | 0.2692 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0226 | 0.0156 | 0.0153 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.037 | 0.0366 | 0.1002 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.3806 | 0.5385 | 0.5385 |
Echinococcus granulosus | Immunoglobulin subtype | 0.0121 | 0.0002 | 0.0002 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0455 | 0.049 | 0.1345 |
Echinococcus granulosus | histone deacetylase 1 | 0.0501 | 0.0558 | 0.0558 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0235 | 0.017 | 0.017 |
Brugia malayi | hypothetical protein | 0.0129 | 0.0015 | 0.0013 |
Brugia malayi | serine/threonine kinase 12 | 0.0123 | 0.0005 | 0.0003 |
Brugia malayi | hypothetical protein | 0.039 | 0.0395 | 0.0393 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0216 | 0.0141 | 0.0139 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0123 | 0.0005 | 0.0003 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0295 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.2589 | 0.3608 | 0.3607 |
Schistosoma mansoni | tyrosine kinase | 0.3806 | 0.5385 | 0.5384 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.0156 | 0.0153 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.4561 | 0.6488 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0179 | 0.0087 | 0.0085 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0269 | 0.0218 | 0.0218 |
Echinococcus granulosus | tyrosine kinase | 0.0269 | 0.0218 | 0.0218 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0963 | 0.1232 | 0.3406 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.037 | 0.0366 | 0.0364 |
Loa Loa (eye worm) | hypothetical protein | 0.0363 | 0.0356 | 0.0354 |
Echinococcus granulosus | histone deacetylase 3 | 0.0501 | 0.0558 | 0.0558 |
Echinococcus granulosus | epidermal growth factor receptor | 0.3806 | 0.5385 | 0.5385 |
Schistosoma mansoni | cell adhesion molecule | 0.0226 | 0.0156 | 0.0153 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0252 | 0.0194 | 0.0194 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0252 | 0.0194 | 0.0525 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0179 | 0.0087 | 0.0087 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0216 | 0.0141 | 0.0141 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0121 | 0.0002 | 0.0002 |
Echinococcus granulosus | tyrosine kinase | 0.0153 | 0.0049 | 0.0049 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0252 | 0.0194 | 0.3425 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0216 | 0.0141 | 0.0141 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0225 | 0.0154 | 0.0413 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0455 | 0.049 | 0.1345 |
Brugia malayi | Protein kinase domain containing protein | 0.2393 | 0.3321 | 0.332 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0501 | 0.0558 | 0.0555 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0501 | 0.0558 | 0.0558 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0232 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 0.0708 | 0.0706 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.0144 | 0.0142 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0269 | 0.0218 | 0.0218 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0225 | 0.0154 | 0.0413 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0501 | 0.0558 | 1 |
Schistosoma mansoni | septate junction protein | 0.0216 | 0.0141 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.1046 | 0.1353 | 0.1351 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0216 | 0.0141 | 0.0139 |
Trypanosoma brucei | histone deacetylase 2 | 0.0235 | 0.017 | 0.0457 |
Schistosoma mansoni | tyrosine kinase | 0.369 | 0.5216 | 0.5215 |
Echinococcus multilocularis | Immunoglobulin | 0.0121 | 0.0002 | 0.0002 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0501 | 0.0558 | 0.0555 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0455 | 0.049 | 0.8774 |
Schistosoma mansoni | tyrosine kinase | 0.369 | 0.5216 | 0.5215 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0225 | 0.0154 | 0.0154 |
Giardia lamblia | Kinase, CMGC CDK | 0.0225 | 0.0154 | 0.2692 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0153 | 0.0049 | 0.0049 |
Schistosoma mansoni | tyrosine kinase | 0.3806 | 0.5385 | 0.5384 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.6965 | 1 | 1 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0131 | 0.0017 | 0.0017 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.2403 | 0.3336 | 0.3336 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0501 | 0.0558 | 0.0555 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.3806 | 0.5385 | 0.5385 |
Plasmodium falciparum | histone deacetylase 1 | 0.0501 | 0.0558 | 1 |
Loa Loa (eye worm) | TK protein kinase | 0.0232 | 0.0164 | 0.0162 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.4957 | 0.7068 | 0.7067 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0153 | 0.0049 | 0.0049 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0179 | 0.0087 | 0.0085 |
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0963 | 0.1232 | 0.3406 |
Trypanosoma brucei | histone deacetylase 3 | 0.0455 | 0.049 | 0.1345 |
Loa Loa (eye worm) | TK protein kinase | 0.0507 | 0.0567 | 0.0565 |
Brugia malayi | Protein kinase domain containing protein | 0.019 | 0.0103 | 0.01 |
Plasmodium vivax | histone deacetylase, putative | 0.0235 | 0.017 | 0.2981 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.0004 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Brugia malayi | Protein kinase domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Loa Loa (eye worm) | histone deacetylase | 0.0455 | 0.049 | 0.0488 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.038 | 0.038 | 0.038 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0252 | 0.0194 | 0.3425 |
Schistosoma mansoni | ephrin receptor | 0.0126 | 0.0009 | 0.0007 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0295 | 0.0256 | 0.0256 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0467 | 0.0507 | 0.0505 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.0184 | 0.0182 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0005 | 0.0003 |
Schistosoma mansoni | cell adhesion molecule | 0.0216 | 0.0141 | 0.0139 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0455 | 0.049 | 0.1345 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.0163 | 0.0161 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Leishmania major | histone deacetylase, putative | 0.0501 | 0.0558 | 0.1533 |
Echinococcus granulosus | aurora kinase A | 0.0123 | 0.0005 | 0.0005 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0295 | 0.0256 | 0.0256 |
Leishmania major | histone deacetylase, putative | 0.0501 | 0.0558 | 0.1533 |
Echinococcus multilocularis | Immunoglobulin | 0.0121 | 0.0002 | 0.0002 |
Schistosoma mansoni | tyrosine kinase | 0.6965 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0295 | 0.0256 | 0.0256 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0412 | 0.0428 | 0.0428 |
Echinococcus multilocularis | 0.2131 | 0.2939 | 0.2939 | |
Echinococcus multilocularis | Immunoglobulin | 0.038 | 0.038 | 0.038 |
Brugia malayi | Fibronectin type III domain containing protein | 0.039 | 0.0395 | 0.0393 |
Entamoeba histolytica | protein kinase, putative | 0.0232 | 0.0164 | 0.2884 |
Echinococcus multilocularis | roundabout 2 | 0.0605 | 0.071 | 0.071 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0225 | 0.0154 | 0.2692 |
Echinococcus multilocularis | insulin receptor | 0.2393 | 0.3321 | 0.3321 |
Leishmania major | histone deacetylase, putative | 0.0455 | 0.049 | 0.1345 |
Schistosoma mansoni | nephrin | 0.0485 | 0.0534 | 0.0532 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0121 | 0.0002 | 0.0002 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0252 | 0.0194 | 0.0192 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0216 | 0.0141 | 0.0139 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0225 | 0.0154 | 0.2692 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0455 | 0.049 | 0.049 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0252 | 0.0194 | 0.0192 |
Schistosoma mansoni | nephrin | 0.0226 | 0.0156 | 0.0153 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0501 | 0.0558 | 0.1533 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0225 | 0.0154 | 0.2692 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0295 | 0.0256 | 0.0256 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0225 | 0.0154 | 0.0413 |
Loa Loa (eye worm) | SRC-1 | 0.0295 | 0.0256 | 0.0254 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0295 | 0.0256 | 0.0256 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0252 | 0.0194 | 0.0525 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0252 | 0.0194 | 0.0525 |
Echinococcus multilocularis | activin receptor type | 0.0123 | 0.0005 | 0.0005 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0455 | 0.049 | 0.1345 |
Brugia malayi | Protein kinase domain containing protein | 0.0363 | 0.0356 | 0.0354 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0005 | 0.0003 |
Echinococcus granulosus | c src tyrosine kinase | 0.0179 | 0.0087 | 0.0087 |
Onchocerca volvulus | 0.0153 | 0.0049 | 0.0041 | |
Schistosoma mansoni | neuroglian | 0.0226 | 0.0156 | 0.0153 |
Schistosoma mansoni | cell adhesion molecule | 0.051 | 0.0571 | 0.0569 |
Echinococcus granulosus | ephrin type A receptor 4 A | 0.0321 | 0.0294 | 0.0294 |
Schistosoma mansoni | tyrosine kinase | 0.2393 | 0.3321 | 0.332 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.017 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.038 | 0.0378 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0235 | 0.017 | 0.0168 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0179 | 0.0087 | 0.0087 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Echinococcus granulosus | hypothetical protein | 0.0245 | 0.0184 | 0.0184 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.2589 | 0.3608 | 0.3608 |
Echinococcus multilocularis | Immunoglobulin | 0.038 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0219 | 0.0146 | 0.0144 |
Onchocerca volvulus | 0.0153 | 0.0049 | 0.0041 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0507 | 0.0567 | 0.0565 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0211 | 0.0134 | 0.0134 |
Brugia malayi | hypothetical protein | 0.0501 | 0.0557 | 0.0555 |
Onchocerca volvulus | 0.0153 | 0.0049 | 0.0041 | |
Echinococcus granulosus | histone deacetylase 6 | 0.0467 | 0.0507 | 0.0507 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0005 | 0.0003 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0269 | 0.0218 | 0.0218 |
Leishmania major | 0.2589 | 0.3608 | 1 | |
Trypanosoma cruzi | histone deacetylase, putative | 0.0235 | 0.017 | 0.0457 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0232 | 0.0164 | 0.0164 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0225 | 0.0154 | 0.0154 |
Giardia lamblia | Kinase, CMGC CLK | 0.0252 | 0.0194 | 0.3425 |
Brugia malayi | SH2 domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Schistosoma mansoni | ephrin receptor | 0.0281 | 0.0237 | 0.0235 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0153 | 0.0049 | 0.0049 |
Schistosoma mansoni | tyrosine kinase | 0.369 | 0.5216 | 0.5215 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0153 | 0.0049 | 0.0049 |
Brugia malayi | Histone deacetylase 1 | 0.0501 | 0.0558 | 0.0555 |
Loa Loa (eye worm) | hypothetical protein | 0.039 | 0.0395 | 0.0393 |
Echinococcus multilocularis | histone deacetylase | 0.0455 | 0.049 | 0.049 |
Loa Loa (eye worm) | TK protein kinase | 0.0269 | 0.0218 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.039 | 0.0395 | 0.0393 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.05 | 0.0557 | 0.0557 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0211 | 0.0134 | 0.0132 |
Echinococcus multilocularis | 0.0245 | 0.0184 | 0.0184 | |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.2589 | 0.3608 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.039 | 0.0395 | 0.0393 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0225 | 0.0154 | 0.0154 |
Echinococcus granulosus | roundabout 2 | 0.0226 | 0.0156 | 0.0156 |
Echinococcus multilocularis | aurora kinase A | 0.0123 | 0.0005 | 0.0005 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0121 | 0.0002 | 0.0002 |
Plasmodium vivax | histone deacetylase, putative | 0.0455 | 0.049 | 0.8774 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0963 | 0.1232 | 0.3406 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0225 | 0.0154 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Brugia malayi | Prion-like- | 0.0216 | 0.0141 | 0.0139 |
Schistosoma mansoni | tyrosine kinase | 0.0295 | 0.0256 | 0.0254 |
Brugia malayi | Protein kinase domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0252 | 0.0194 | 0.0194 |
Echinococcus granulosus | cyclin dependent kinase | 0.0225 | 0.0154 | 0.0154 |
Echinococcus granulosus | contactin | 0.0235 | 0.0168 | 0.0168 |
Schistosoma mansoni | tyrosine kinase | 0.0295 | 0.0256 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0501 | 0.0557 | 0.0555 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0455 | 0.049 | 0.0488 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0129 | 0.0015 | 0.0013 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0467 | 0.0507 | 0.0507 |
Brugia malayi | Protein kinase domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0252 | 0.0194 | 0.0525 |
Echinococcus multilocularis | hemicentin 1 | 0.0216 | 0.0141 | 0.0141 |
Echinococcus granulosus | lachesin | 0.0216 | 0.0141 | 0.0141 |
Schistosoma mansoni | tyrosine kinase | 0.0332 | 0.031 | 0.0308 |
Leishmania major | protein kinase, putative | 0.0252 | 0.0194 | 0.0525 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0252 | 0.0194 | 0.3425 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0225 | 0.0154 | 0.0413 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0295 | 0.0256 | 0.0256 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0123 | 0.0005 | 0.0005 |
Echinococcus multilocularis | tyrosine kinase | 0.0153 | 0.0049 | 0.0049 |
Echinococcus granulosus | Immunoglobulin | 0.0121 | 0.0002 | 0.0002 |
Leishmania major | protein kinase, putative | 0.0252 | 0.0194 | 0.0525 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0153 | 0.0049 | 0.0049 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.2589 | 0.3608 | 0.3607 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0225 | 0.0154 | 0.0154 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0211 | 0.0134 | 0.0134 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0455 | 0.049 | 0.049 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0226 | 0.0156 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.038 | 0.0378 |
Echinococcus granulosus | dual specificity | 0.037 | 0.0366 | 0.0366 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0226 | 0.0156 | 0.0156 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0252 | 0.0194 | 0.0525 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.0022 | 0.002 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0153 | 0.0049 | 0.0049 |
Leishmania major | histone deacetylase, putative | 0.0455 | 0.049 | 0.1345 |
Plasmodium falciparum | histone deacetylase 2 | 0.0455 | 0.049 | 0.8774 |
Brugia malayi | cell division control protein 2 homolog | 0.0225 | 0.0154 | 0.0152 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0179 | 0.0087 | 0.0087 |
Onchocerca volvulus | 0.0166 | 0.0068 | 0.007 | |
Entamoeba histolytica | protein kinase, putative | 0.037 | 0.0366 | 0.6534 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0295 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0225 | 0.0154 | 0.0152 |
Brugia malayi | Protein kinase domain containing protein | 0.0153 | 0.0049 | 0.0047 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0233 | 0.0166 | 0.0164 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0225 | 0.0154 | 0.0413 |
Giardia lamblia | Histone deacetylase | 0.0501 | 0.0558 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0216 | 0.0141 | 0.0139 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0226 | 0.0156 | 0.0153 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0252 | 0.0194 | 0.0192 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0225 | 0.0154 | 0.0152 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0179 | 0.0087 | 0.0087 |
Echinococcus granulosus | neuroglian | 0.0475 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | AUR protein kinase | 0.0123 | 0.0005 | 0.0003 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0226 | 0.0156 | 0.0156 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0269 | 0.0218 | 0.0218 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0412 | 0.0428 | 0.0428 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0153 | 0.0049 | 0.0049 |
Plasmodium falciparum | histone deacetylase, putative | 0.0455 | 0.049 | 0.8774 |
Echinococcus granulosus | epidermal growth factor receptor | 0.6965 | 1 | 1 |
Plasmodium falciparum | protein kinase, putative | 0.0123 | 0.0005 | 0.0002 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.4957 | 0.7068 | 0.7067 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0153 | 0.0049 | 0.0049 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0235 | 0.017 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0375 | 0.0373 | 0.0371 |
Echinococcus granulosus | twitchin | 0.0482 | 0.053 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.039 | 0.0395 | 0.0393 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0235 | 0.017 | 0.0457 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.037 | 0.0366 | 0.1002 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0235 | 0.017 | 0.0457 |
Echinococcus granulosus | roundabout 2 | 0.0226 | 0.0156 | 0.0156 |
Schistosoma mansoni | tyrosine kinase | 0.0153 | 0.0049 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.0696 | 0.0694 |
Loa Loa (eye worm) | TK/EPH protein kinase | 0.0327 | 0.0303 | 0.0301 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0295 | 0.0256 | 0.0256 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.2589 | 0.3608 | 0.3607 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0501 | 0.0558 | 0.0555 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0295 | 0.0256 | 0.0256 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0295 | 0.0256 | 0.0256 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0121 | 0.0002 | 0.0002 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0501 | 0.0558 | 1 |
Brugia malayi | SRC-1 | 0.0295 | 0.0256 | 0.0254 |
Echinococcus multilocularis | Immunoglobulin subtype | 0.0121 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.0068 | 0.0065 |
Schistosoma mansoni | protein kinase | 0.0123 | 0.0005 | 0.0003 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0235 | 0.017 | 0.0228 |
Brugia malayi | Protein kinase domain containing protein | 0.037 | 0.0366 | 0.0364 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.2403 | 0.3336 | 0.3336 |
Loa Loa (eye worm) | AUR protein kinase | 0.0123 | 0.0005 | 0.0003 |
Brugia malayi | SH2 domain containing protein | 0.0375 | 0.0373 | 0.0371 |
Echinococcus multilocularis | roundabout 2 | 0.0226 | 0.0156 | 0.0156 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.0004 | 0.0002 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0235 | 0.017 | 0.0168 |
Brugia malayi | Histone deacetylase family protein | 0.0455 | 0.049 | 0.0488 |
Trypanosoma brucei | histone deacetylase 4 | 0.0455 | 0.049 | 0.1345 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0153 | 0.0049 | 0.0047 |
Echinococcus multilocularis | dual specificity | 0.037 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.2393 | 0.3321 | 0.332 |
Entamoeba histolytica | histone deacetylase, putative | 0.0501 | 0.0558 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0123 | 0.0005 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.0022 | 0.002 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0225 | 0.0154 | 0.0203 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0153 | 0.0049 | 0.0047 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0501 | 0.0558 | 0.1533 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0226 | 0.0156 | 0.0153 |
Plasmodium vivax | protein kinase Crk2 | 0.0225 | 0.0154 | 0.2692 |
Brugia malayi | Protein kinase domain containing protein | 0.0225 | 0.0154 | 0.0152 |
Echinococcus granulosus | cyclin dependent kinase 5 activator 1 | 0.1046 | 0.1353 | 0.1353 |
Entamoeba histolytica | protein kinase domain containing protein | 0.037 | 0.0366 | 0.6534 |
Trypanosoma brucei | histone deacetylase 1 | 0.0501 | 0.0558 | 0.1533 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.0141 | 0.0139 |
Echinococcus granulosus | 3'partial|cell adhesion molecule:down regulated by | 0.0121 | 0.0002 | 0.0002 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 54 nM | Inhibition of binding of [3H]-N6-cyclohexyladenosine to adenosine A1 receptor of rat whole brain membranes. | ChEMBL. | 2754691 |
Ki (binding) | = 450 nM | Inhibition of binding of [3H]-NECA to adenosine A2 receptor of rat striatal membranes. | ChEMBL. | 2754691 |
Ratio (binding) | = 8.4 | Selectivity ratio for A1 receptor to that of A2 receptor in vitro in rat tissues | ChEMBL. | 2754691 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.