Detailed information for compound 66065

Basic information

Technical information
  • TDR Targets ID: 66065
  • Name: 8-chloro-3-(chloromethyl)-5-methyl-4H-imidazo [1,5-a][1,4]benzodiazepin-6-one
  • MW: 296.152 | Formula: C13H11Cl2N3O
  • H donors: 0 H acceptors: 2 LogP: 1.79 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClCc1ncn2c1CN(C)C(=O)c1c2ccc(c1)Cl
  • InChi: 1S/C13H11Cl2N3O/c1-17-6-12-10(5-14)16-7-18(12)11-3-2-8(15)4-9(11)13(17)19/h2-4,7H,5-6H2,1H3
  • InChiKey: YRUBZMJUTFFYRW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 2 Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2 Starlite/ChEMBL References
Rattus norvegicus GABA-A receptor; anion channel Starlite/ChEMBL References
Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129441 All targets in OG5_129441
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129441 All targets in OG5_129441
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131775 All targets in OG5_131775
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor Get druggable targets OG5_129441 All targets in OG5_129441
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 461 aa 27.8 %
Brugia malayi excitatory GABA receptor EXP-1A gamma-aminobutyric acid (GABA) A receptor, beta 3 473 aa 441 aa 29.9 %
Echinococcus granulosus glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 439 aa 29.6 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, alpha 2 451 aa 393 aa 25.9 %
Onchocerca volvulus Large subunit GTPase 1 homolog GABA-A receptor; anion channel   467 aa 496 aa 26.0 %
Echinococcus multilocularis glycine receptor subunit beta GABA-A receptor; anion channel   467 aa 478 aa 28.7 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 494 aa 25.5 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 435 aa 29.7 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 468 aa 28.6 %
Brugia malayi Cation transporter family protein GABA-A receptor; anion channel   467 aa 453 aa 28.5 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein gamma-aminobutyric acid (GABA) A receptor, gamma 2 467 aa 449 aa 27.6 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 454 aa 29.5 %
Onchocerca volvulus Gamma-aminobutyric acid receptor subunit beta homolog GABA-A receptor; anion channel   467 aa 433 aa 34.6 %
Schistosoma mansoni Cys-loop ligand gated ion channel subunit GABA-A receptor; anion channel   467 aa 479 aa 29.2 %
Echinococcus granulosus glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative GABA-A receptor; anion channel   467 aa 384 aa 19.5 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 446 aa 29.1 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 446 aa 28.0 %
Loa Loa (eye worm) hypothetical protein GABA-A receptor; anion channel   467 aa 441 aa 33.8 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 434 aa 26.7 %
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein GABA-A receptor; anion channel   467 aa 375 aa 21.9 %
Onchocerca volvulus Eukaryotic initiation factor 4A-III homolog GABA-A receptor; anion channel   467 aa 453 aa 26.9 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 454 aa 30.4 %
Onchocerca volvulus Acetylcholine receptor subunit alpha-type homolog GABA-A receptor; anion channel   467 aa 418 aa 19.6 %
Echinococcus multilocularis glycine receptor subunit alpha 1 GABA-A receptor; anion channel   467 aa 430 aa 32.3 %
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit GABA-A receptor; anion channel   467 aa 379 aa 19.3 %
Onchocerca volvulus GABA-A receptor; anion channel   467 aa 447 aa 25.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 0.9839
Plasmodium vivax metacaspase 1, putative 0.0029 0.0009 0.0009
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0155 0.0174
Brugia malayi ecdysteroid receptor 0.0688 0.2723 0.4258
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0133 0.0436 0.0757
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0165 0.0247
Echinococcus granulosus heat shock protein 90 0.0042 0.0062 0.0069
Mycobacterium tuberculosis Possible oxidoreductase 0.0036 0.0035 0.006
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Giardia lamblia Histone acetyltransferase GCN5 0.0123 0.0395 0.1104
Loa Loa (eye worm) hypothetical protein 0.1325 0.5347 0.5344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0252 0.0926 0.1441
Schistosoma mansoni fatty acid binding protein 0.0205 0.0732 0.0817
Brugia malayi Cation transporter family protein 0.0536 0.2095 0.3273
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0461 0.1789 0.2007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Echinococcus multilocularis nervana 2 0.0062 0.0142 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Loa Loa (eye worm) hypothetical protein 0.0051 0.0096 0.009
Echinococcus multilocularis caspase 2 0.0029 0.0009 0.001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0067 0.0166 0.0448
Brugia malayi Pre-SET motif family protein 0.1049 0.4211 0.6592
Onchocerca volvulus Neuropeptide F receptor homolog 0.0047 0.0083 0.0154
Schistosoma mansoni hypothetical protein 0.0042 0.0063 0.0063
Echinococcus multilocularis fatty acid binding protein FABP2 0.0067 0.0165 0.0185
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0051 0.0099 0.0171
Trichomonas vaginalis DNA polymerase eta, putative 0.0085 0.0238 0.0496
Brugia malayi jmjC domain containing protein 0.0059 0.0132 0.0196
Schistosoma mansoni organic anion transporter 0.0029 0.0009 0.0002
Brugia malayi jmjC domain containing protein 0.0044 0.0071 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0064 0.0132
Onchocerca volvulus Cathepsin L homolog 0.0087 0.0247 0.0496
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0121 0.0388 0.0806
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0117 0.037 0.4995
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.05 0.1039
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0252 0.0926 0.1441
Trypanosoma cruzi heat shock protein 85, putative 0.0042 0.0062 0.0175
Echinococcus granulosus importin subunit beta 1 0.0058 0.0129 0.0144
Toxoplasma gondii aldehyde dehydrogenase 0.0183 0.0643 0.1813
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0017
Brugia malayi cytoplasmic intermediate filament protein 0.0076 0.0202 0.0305
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0135 0.0445 0.05
Brugia malayi RNA, U transporter 1 0.0166 0.0572 0.0885
Plasmodium falciparum cysteine proteinase falcipain 1 0.0045 0.0073 0.0192
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0148 0.05 0.0772
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Loa Loa (eye worm) hypothetical protein 0.0084 0.0236 0.0229
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0148 0.05 0.0868
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0229 0.025
Onchocerca volvulus 0.0284 0.1057 0.2184
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0583
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0047 0.0083 0.0093
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0688 0.2723 0.2718
Loa Loa (eye worm) abnormal epIthelia family member 0.0051 0.0096 0.009
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0284 0.1057 0.1646
Entamoeba histolytica glycogenphosphorylase, putative 0.0049 0.0092 0.0194
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0095 0.0278 0.0312
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma brucei aldo-keto reductase, putative 0.0067 0.0165 0.0443
Echinococcus multilocularis musashi 0.0142 0.0473 0.0532
Echinococcus granulosus aldo keto reductase 0.0067 0.0165 0.0185
Schistosoma mansoni DNA topoisomerase type I 0.0206 0.0738 0.0823
Plasmodium falciparum importin beta, putative 0.0058 0.0129 0.035
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0181 0.0635 0.0715
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma cruzi metacaspase, putative 0.0029 0.0009 0.0024
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0095 0.0278 0.0479
Entamoeba histolytica cysteine protease, putative 0.0087 0.0247 0.0631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0069 0.0172 0.0357
Echinococcus multilocularis heat shock protein 90 0.0042 0.0062 0.0069
Plasmodium falciparum DNA topoisomerase 2 0.0161 0.0552 0.1553
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0039 0.0066
Echinococcus granulosus glycine receptor subunit beta 0.0536 0.2095 0.2357
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0051 0.0099 0.0171
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0044 0.0071 0.0186
Schistosoma mansoni cpg binding protein 0.0197 0.0701 0.0781
Entamoeba histolytica hypothetical protein 0.0297 0.1113 0.3064
Brugia malayi Cell death protein 3 precursor 0.0029 0.0009 0.0003
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0036 0.0035 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0035 0.0039
Echinococcus multilocularis steroid dehydrogenase 0.0036 0.0035 0.0039
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0148 0.0496 0.0558
Echinococcus granulosus serotonin receptor 0.0047 0.0083 0.0093
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0103 0.0313 0.0352
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0067 0.0165 0.0158
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0046 0.0079 0.0158
Echinococcus granulosus orexin receptor type 2 0.0047 0.0083 0.0093
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.0318 0.0358
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.0318 0.088
Loa Loa (eye worm) hypothetical protein 0.0652 0.2576 0.2571
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0044 0.0071 0.0177
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0033 0.0024 0.0052
Brugia malayi nuclear hormone receptor family member odr-7 0.0181 0.0635 0.0985
Echinococcus granulosus 7TM GPCR rhodopsin 0.0047 0.0083 0.0093
Loa Loa (eye worm) tyrosinase 1 0.0091 0.0261 0.0255
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0163
Echinococcus multilocularis fatty acid binding protein FABP2 0.0205 0.0732 0.0823
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.1577 0.6385 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0019
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0033 0.0024 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Echinococcus granulosus glycine receptor subunit alpha 1 0.0536 0.2095 0.2357
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0236 0.0668
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trichomonas vaginalis heat shock protein, putative 0.0027 0 0.0001
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0035 0.0035
Plasmodium vivax topoisomerase I, putative 0.0206 0.0738 0.2081
Trichomonas vaginalis aldo/keto reductase, putative 0.0067 0.0165 0.0343
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0109 0.0339 0.0381
Brugia malayi Dopamine receptor protein 1 0.0047 0.0083 0.0119
Loa Loa (eye worm) hypothetical protein 0.0043 0.0067 0.006
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0061 0.0138 0.0206
Brugia malayi Fli-1 protein 0.0706 0.2795 0.4371
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0192 0.0216
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Echinococcus granulosus GA binding protein alpha chain 0.0232 0.0846 0.0951
Brugia malayi intermediate filament protein 0.0142 0.0473 0.0731
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0083 0.0093
Echinococcus granulosus GPCR family 2 0.0065 0.0155 0.0174
Leishmania major cathepsin L-like protease 0.0087 0.0247 0.07
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Loa Loa (eye worm) hypothetical protein 0.006 0.0134 0.0127
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0091 0.0261 0.0399
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0153 0.052 0.1462
Loa Loa (eye worm) hypothetical protein 0.006 0.0134 0.0127
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.015 0.0506 0.0569
Onchocerca volvulus 0.0036 0.0035 0.0054
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0155 0.0232
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0051 0.0096 0.0101
Schistosoma mansoni hypothetical protein 0.0287 0.1069 0.1196
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0882 0.3522 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Leishmania major short chain dehydrogenase/reductase, putative 0.0036 0.0035 0.0098
Echinococcus multilocularis serotonin receptor 0.0047 0.0083 0.0093
Echinococcus multilocularis glycogen phosphorylase 0.0114 0.0358 0.0403
Echinococcus granulosus histone lysine methyltransferase setb 0.0188 0.0664 0.0747
Entamoeba histolytica glycogen phosphorylase, putative 0.0114 0.0358 0.0944
Echinococcus multilocularis sodium bile acid cotransporter 0.053 0.2072 0.2331
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0047 0.0083 0.0154
Brugia malayi orphan nuclear receptor NR2E1 0.0181 0.0635 0.0985
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Trypanosoma cruzi UDP-glucoronosyl and UDP-glucosyl transferase, putative 0.0054 0.011 0.031
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0065 0.0073
Brugia malayi PHD-finger family protein 0.0076 0.0202 0.0306
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0048 0.0086 0.0175
Loa Loa (eye worm) phosphofructokinase 0.0223 0.0805 0.0799
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0061 0.0138 0.0131
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0155 0.0174
Onchocerca volvulus 0.0036 0.0035 0.0054
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0036 0.0035 0.006
Onchocerca volvulus 0.0047 0.0083 0.0154
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0136 0.0283
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0036 0.0035 0.0073
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0033 0.0025 0.0069
Schistosoma mansoni hypothetical protein 0.0043 0.0067 0.0068
Leishmania major farnesyltransferase beta subunit 0.0121 0.0388 0.1099
Plasmodium falciparum DNA gyrase subunit B 0.0097 0.0287 0.0801
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0444 0.1719 0.2987
Toxoplasma gondii phosphofructokinase domain-containing protein 0.006 0.0136 0.0371
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0086 0.0447
Toxoplasma gondii 6-phosphofructokinase 0.006 0.0136 0.0371
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Entamoeba histolytica heat shock protein 90, putative 0.0042 0.0062 0.0111
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0536 0.2095 0.2357
Loa Loa (eye worm) hypothetical protein 0.0079 0.0213 0.0206
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0103 0.029
Trypanosoma cruzi cysteine peptidase, putative 0.0331 0.1254 0.3559
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0077 0.0193
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0056 0.0063
Echinococcus granulosus fmrfamide receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.0623 0.2455 0.2449
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0062 0.0146 0.0303
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0136 0.0371
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0896 0.358 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0056 0.0117
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0248 0.0241
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0051 0.0099 0.0171
Schistosoma mansoni caspase-3 (C14 family) 0.0109 0.0339 0.0374
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.018 0.063 0.1787
Entamoeba histolytica cysteine proteinase, putative 0.0045 0.0073 0.0142
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 0.9839
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0029 0.0009 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0083 0.0093
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0047 0.0083 0.0093
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0051 0.0099 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0252 0.0926 0.1441
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0063 0.013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Brugia malayi nuclear hormone receptor 0.0181 0.0635 0.0985
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0135 0.0445 0.1241
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0029 0.0008 0.0009
Toxoplasma gondii ATP-citrate lyase, putative 0.0053 0.0108 0.0291
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0536 0.2095 0.3273
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0035 0.0083
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0051 0.0099 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0134 0.0279
Loa Loa (eye worm) TOPoisomerase family member 0.0161 0.0552 0.0545
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0036 0.0035 0.0098
Loa Loa (eye worm) hypothetical protein 0.0104 0.0318 0.0311
Brugia malayi putative neuropeptide receptor 0.0047 0.0083 0.0119
Schistosoma mansoni amine GPCR 0.0047 0.0083 0.0085
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0384 0.1472 0.1656
Echinococcus granulosus delta aminolevulinic acid dehydratase 0.0207 0.074 0.0832
Loa Loa (eye worm) hypothetical protein 0.0148 0.05 0.0493
Schistosoma mansoni acetylcholine receptor-related 0.0252 0.0926 0.1035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0392 0.1505 0.4263
Echinococcus granulosus hypothetical protein 0.0036 0.0035 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0019
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0051 0.0099 0.0172
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0047 0.0083 0.0085
Chlamydia trachomatis glycogen phosphorylase 0.0114 0.0358 0.0953
Toxoplasma gondii carbonyl reductase 1, putative 0.0036 0.0035 0.0083
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Onchocerca volvulus 0.0087 0.0247 0.0496
Trichomonas vaginalis helicase, putative 0.0034 0.0027 0.0057
Loa Loa (eye worm) fli-1 protein 0.0706 0.2795 0.279
Giardia lamblia Glycogen phosphorylase 0.0114 0.0358 0.1
Echinococcus granulosus muscleblind protein 0.0149 0.0502 0.0565
Loa Loa (eye worm) nuclear hormone receptor 0.0181 0.0635 0.0629
Brugia malayi Cathepsin L-like precursor 0.0087 0.0247 0.0376
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Schistosoma mansoni lamin 0.0142 0.0473 0.0525
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0148 0.05 0.0555
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0875 0.0985
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.018
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0161 0.0552 0.0621
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0056 0.0063
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1049 0.4211 0.4207
Leishmania major hypothetical protein, conserved 0.0214 0.077 0.2186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Onchocerca volvulus 0.0148 0.05 0.1022
Chlamydia trachomatis DNA gyrase subunit B 0.0078 0.021 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0047
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0046 0.0079 0.0112
Schistosoma mansoni fatty acid binding protein 0.0205 0.0732 0.0817
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0095 0.0278 0.0312
Brugia malayi hypothetical protein 0.0252 0.0926 0.1441
Echinococcus multilocularis caspase 8 0.0029 0.0009 0.001
Echinococcus granulosus lamin dm0 0.0142 0.0473 0.0532
Loa Loa (eye worm) 6-phosphofructokinase 0.0223 0.0805 0.0799
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0033 0.0025 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0181 0.0635 0.0985
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0252 0.0926 0.1441
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0536 0.2095 0.3273
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0051 0.0099 0.0172
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0088 0.0128
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0083 0.0093
Trypanosoma cruzi lanosterol synthase, putative 0.0133 0.0436 0.1237
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0313 0.0345
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0536 0.2095 0.3273
Brugia malayi isocitrate dehydrogenase 0.0033 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0057 0.0123 0.0116
Schistosoma mansoni patched 1 0.0043 0.0064 0.0064
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0062 0.0142 0.0159
Entamoeba histolytica hypothetical protein 0.006 0.0134 0.0314
Loa Loa (eye worm) hypothetical protein 0.0083 0.0229 0.0222
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0023 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0384 0.1472 0.2297
Leishmania major 3-keto-dihydrosphingosine reductase 0.0036 0.0035 0.0098
Schistosoma mansoni caspase-7 (C14 family) 0.0109 0.0339 0.0374
Schistosoma mansoni aldo-keto reductase 0.0067 0.0165 0.0178
Echinococcus multilocularis serotonin receptor 0.0047 0.0083 0.0093
Brugia malayi Probable ClpP-like protease 0.0083 0.0229 0.0348
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0043 0.0067 0.0075
Echinococcus granulosus glycine receptor subunit alpha 1 0.0536 0.2095 0.2357
Trypanosoma cruzi Heat shock protein 83, putative 0.0042 0.0062 0.0175
Loa Loa (eye worm) hypothetical protein 0.0148 0.05 0.0493
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0131 0.0125
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0067 0.0165 0.0466
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0536 0.2095 0.2357
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Schistosoma mansoni 6-phosphofructokinase 0.0223 0.0805 0.0899
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0135 0.0445 0.1262
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0064 0.0057
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0091 0.0261 0.0399
Trypanosoma brucei DNA polymerase IV, putative 0.0085 0.0238 0.0653
Schistosoma mansoni acetylcholine receptor subunit beta 0.0252 0.0926 0.1035
Leishmania major lanosterol synthase, putative 0.01 0.0301 0.0853
Brugia malayi RNA binding protein 0.0516 0.2013 0.3146
Schistosoma mansoni cpg binding protein 0.0215 0.0774 0.0863
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0487 0.1896 0.2133
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Echinococcus multilocularis transcription factor Dp 1 0.0119 0.0377 0.0424
Mycobacterium ulcerans beta-lactamase 0.0148 0.05 0.0861
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.01 0.0301 0.0338
Brugia malayi Melatonin receptor type 1A 0.0047 0.0083 0.0119
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.0238 0.0676
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Brugia malayi phosphofructokinase 0.0223 0.0805 0.1252
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0034 0.0027 0.003
Echinococcus granulosus ETS domain containing protein Elk 1 0.0034 0.0027 0.003
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0135 0.0445 0.1187
Plasmodium vivax glutathione reductase, putative 0.0195 0.0691 0.1948
Plasmodium falciparum JmjC domain-containing protein, putative 0.0066 0.0159 0.0437
Schistosoma mansoni opsin-like receptor 0.0047 0.0083 0.0085
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0392 0.1505 0.2349
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0065 0.0169
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0121 0.0388 0.0597
Plasmodium falciparum cysteine proteinase falcipain 3 0.0087 0.0247 0.0686
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0036 0.0035 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Loa Loa (eye worm) acetylcholine receptor protein 0.0252 0.0926 0.092
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Loa Loa (eye worm) cysteine protease 0.0087 0.0247 0.024
Onchocerca volvulus Sepiapterin reductase homolog 0.0036 0.0035 0.0054
Brugia malayi nuclear receptor RXR 0.0181 0.0635 0.0985
Plasmodium falciparum thioredoxin reductase 0.0195 0.0691 0.1948
Schistosoma mansoni hypothetical protein 0.0065 0.0155 0.0167
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0536 0.2095 0.2351
Brugia malayi Serotonin receptor 0.0047 0.0083 0.0119
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0051 0.0099 0.0171
Loa Loa (eye worm) hypothetical protein 0.0188 0.0664 0.0658
Mycobacterium ulcerans esterase/lipase LipP 0.0148 0.05 0.0861
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Leishmania major ATP-dependent phosphofructokinase 0.0223 0.0805 0.2285
Mycobacterium tuberculosis Probable oxidoreductase 0.0067 0.0165 0.0286
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0051 0.0099 0.0172
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0392 0.1505 0.1693
Echinococcus granulosus dna polymerase eta 0.0057 0.0123 0.0137
Onchocerca volvulus 0.0067 0.0165 0.0324
Echinococcus granulosus ETS transcription factor Elf 2 0.0034 0.0027 0.003
Leishmania major short chain dehydrogenase-like protein 0.0036 0.0035 0.0098
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0036 0.0035 0.0098
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0046 0.0079 0.0163
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0353 0.1342 0.1509
Schistosoma mansoni terminal deoxycytidyl transferase 0.0057 0.0123 0.013
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0036 0.0035 0.0035
Brugia malayi 6-phosphofructokinase 0.0223 0.0805 0.1252
Echinococcus multilocularis aldo keto reductase 0.0067 0.0165 0.0185
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0205 0.0733 0.1998
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0536 0.2095 0.2357
Loa Loa (eye worm) oxidoreductase 0.0067 0.0165 0.0158
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.01 0.0301 0.0338
Echinococcus multilocularis sex peptide receptor 0.0047 0.0083 0.0093
Echinococcus granulosus tumor protein p63 0.0373 0.1423 0.1601
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0111 0.0346 0.0702
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0117 0.037 0.0637
Brugia malayi Melibiase family protein 0.0069 0.0172 0.0258
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0576 0.2262 0.6415
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0083 0.0093
Trypanosoma cruzi short chain dehydrogenase, putative 0.0036 0.0035 0.0098
Trypanosoma cruzi protein farnesyltransferase, putative 0.0121 0.0388 0.1099
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0087 0.0247 0.0686
Brugia malayi dehydrogenases, short chain protein 2 0.0036 0.0035 0.0044
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0087 0.0247 0.0686
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0036 0.0035 0.0083
Plasmodium vivax DNA gyrase subunit A, putative 0.0033 0.0025 0.0055
Brugia malayi Cathepsin L-like precursor 0.0087 0.0247 0.0376
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Loa Loa (eye worm) ctsf protein 0.0087 0.0247 0.024
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0048 0.0086 0.024
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Brugia malayi DNA topoisomerase I 0.0206 0.0738 0.1145
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Leishmania major DNA polymerase kappa, putative 0.0064 0.0151 0.0428
Schistosoma mansoni myosin xvIII 0.0047 0.0083 0.0085
Loa Loa (eye worm) ets-domain-containing protein 0.0034 0.0027 0.002
Trypanosoma cruzi heat shock protein 90, putative 0.0042 0.0062 0.0175
Echinococcus granulosus cathepsin l1 0.0087 0.0247 0.0277
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0117 0.037 0.0976
Mycobacterium leprae Probable oxidoreductase 0.0036 0.0035 0.018
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0046 0.0079 0.0163
Loa Loa (eye worm) hypothetical protein 0.01 0.0301 0.0294
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0083 0.0093
Giardia lamblia Aldose reductase 0.0067 0.0165 0.0459
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0062 0.0129
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Echinococcus multilocularis fetal alzheimer antigen, falz 0.006 0.0136 0.0152
Mycobacterium ulcerans short-chain type oxidoreductase 0.0036 0.0035 0.006
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0067 0.0166 0.0289
Loa Loa (eye worm) hypothetical protein 0.0066 0.016 0.0153
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0063 0.0063
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0135 0.0445 0.0926
Schistosoma mansoni regulator of G protein signaling 0.006 0.0134 0.0143
Onchocerca volvulus 0.0142 0.0473 0.0967
Entamoeba histolytica cysteine proteinase, putative 0.0045 0.0073 0.0142
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0297 0.1113 0.1252
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0203 0.0725 0.0809
Mycobacterium leprae Conserved hypothetical protein 0.0051 0.0099 0.0515
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0181 0.0635 0.0715
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0051 0.0099 0.0172
Loa Loa (eye worm) hypothetical protein 0.0205 0.0731 0.0725
Leishmania major cathepsin L-like protease 0.0087 0.0247 0.07
Brugia malayi nuclear hormone receptor family member nhr-6 0.0181 0.0635 0.0985
Trypanosoma brucei trypanothione reductase 0.0195 0.0691 0.1941
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Brugia malayi neuropeptide F receptor 0.0047 0.0083 0.0119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.003
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0036 0.0035 0.018
Onchocerca volvulus 0.0047 0.0083 0.0154
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0292 0.1093 0.3101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0384 0.1472 0.3048
Brugia malayi hypothetical protein 0.0277 0.1029 0.1603
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0438 0.1692 0.294
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.006 0.0136 0.0145
Schistosoma mansoni zinc finger protein 0.0181 0.0635 0.0708
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0183 0.0643 0.1118
Echinococcus granulosus cpg binding protein 0.0215 0.0774 0.087
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0083 0.0093
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0064 0.0151 0.0262
Onchocerca volvulus 0.0087 0.0247 0.0496
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0135 0.0445 0.1249
Giardia lamblia Synaptic glycoprotein SC2 0.0046 0.0079 0.0218
Schistosoma mansoni RAR-like nuclear receptor 0.0384 0.1472 0.165
Loa Loa (eye worm) hypothetical protein 0.0149 0.0502 0.0496
Loa Loa (eye worm) TYRA-2 protein 0.0047 0.0083 0.0076
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0047 0.0083 0.0085
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0222
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0051 0.0099 0.0281
Brugia malayi ShTK domain containing protein 0.0091 0.0261 0.0399
Trypanosoma brucei DNA polymerase IV, putative 0.0085 0.0238 0.0653
Loa Loa (eye worm) thioredoxin reductase 0.0195 0.0691 0.0684
Echinococcus granulosus ETS transcription factor Elf 2 0.0034 0.0027 0.003
Echinococcus granulosus ubiquitin specific protease 41 0.0084 0.0236 0.0265
Schistosoma mansoni cathepsin F (C01 family) 0.0087 0.0247 0.027
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0057 0.0123 0.0116
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0318 0.0662
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0536 0.2095 0.2089
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0252 0.0926 0.1042
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0065 0.0091
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0117 0.037 0.0642
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Plasmodium falciparum glutathione reductase 0.0067 0.0166 0.0457
Schistosoma mansoni ap endonuclease 0.0117 0.037 0.0409
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Brugia malayi PXA domain containing protein 0.006 0.0134 0.02
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0051 0.0099 0.0172
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0252 0.0926 0.1042
Brugia malayi jmjC domain containing protein 0.0062 0.0145 0.0216
Loa Loa (eye worm) hypothetical protein 0.0392 0.1505 0.1499
Onchocerca volvulus 0.0067 0.0165 0.0324
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0392 0.1505 0.1499
Loa Loa (eye worm) CHromoDomain protein family member 0.0029 0.0008 0.0002
Treponema pallidum NADH oxidase 0.0067 0.0166 0.0464
Schistosoma mansoni intermediate filament proteins 0.0142 0.0473 0.0525
Brugia malayi hypothetical protein 0.0029 0.0009 0.0003
Trypanosoma brucei unspecified product 0.0039 0.005 0.0116
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0067 0.0165 0.0343
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0148 0.05 0.0493
Echinococcus multilocularis neuropeptide s receptor 0.053 0.2073 0.2332
Echinococcus multilocularis Glycosyl transferase, family 35 0.0114 0.0358 0.0403
Schistosoma mansoni laminin gamma-3 chain 0.0051 0.0096 0.0101
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.0731 0.0725
Trypanosoma brucei oxidoreductase-like protein 0.0036 0.0035 0.0074
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0036 0.0035 0.0028
Toxoplasma gondii melibiase subfamily protein 0.0103 0.0313 0.0874
Trypanosoma cruzi major cysteine proteinase, putative 0.0261 0.0962 0.273
Brugia malayi hypothetical protein 0.0036 0.0035 0.0044
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0036 0.0035 0.006
Brugia malayi N-terminal motif family protein 0.0199 0.0708 0.11
Mycobacterium ulcerans delta-aminolevulinic acid dehydratase 0.0207 0.074 0.1275
Echinococcus multilocularis protein C ets 2 0.0034 0.0027 0.003
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0033 0.0024 0.0027
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0067 0.0166 0.0448
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0153 0.052 0.0585
Brugia malayi Rhodanese-like domain containing protein 0.0062 0.0146 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0138 0.0148
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0047 0.0083 0.0085
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0051 0.0099 0.0172
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0083 0.0085
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0065 0.0181
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0034 0.0027 0.0023
Onchocerca volvulus Putative nachr subunit 0.0536 0.2095 0.4346
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0321 0.121 0.1355
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Schistosoma mansoni DNA polymerase eta 0.0057 0.0123 0.013
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0643 0.0717
Leishmania major cathepsin L-like protease 0.0087 0.0247 0.07
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0051 0.0099 0.0171
Trichomonas vaginalis penicillin-binding protein, putative 0.0148 0.05 0.1039
Echinococcus multilocularis slit 2 protein 0.0051 0.0097 0.0109
Onchocerca volvulus 0.0036 0.0035 0.0054
Echinococcus granulosus 7tm_1 domain containing protein 0.0047 0.0083 0.0093
Echinococcus granulosus L aminoadipate semialdehyde 0.0171 0.0592 0.0666
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0095 0.0278 0.0305
Brugia malayi Cytochrome P450 family protein 0.0087 0.0248 0.0378
Loa Loa (eye worm) hypothetical protein 0.0095 0.0279 0.0273
Trypanosoma brucei prostaglandin f synthase 0.0067 0.0165 0.0443
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0033 0.0025 0.0043
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0056 0.0158
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0205 0.0733 0.1139
Loa Loa (eye worm) GABA receptor subunit 0.0284 0.1057 0.1051
Echinococcus granulosus dna polymerase kappa 0.0085 0.0238 0.0268
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0882 0.3522 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0384 0.1472 0.2297
Brugia malayi putative neuropeptide receptor NPR1 0.0047 0.0083 0.0119
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Echinococcus granulosus regulator of G protein signaling 7 0.0069 0.0175 0.0196
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0084 0.0236 0.0657
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Giardia lamblia Rab geranylgeranyltransferase 0.0033 0.0024 0.0065
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0171 0.0592 0.0659
Echinococcus granulosus pikachurin 0.0051 0.0096 0.0108
Mycobacterium leprae PROBABLE DELTA-AMINOLEVULINIC ACID DEHYDRATASE HEMB (PORPHOBILINOGEN SYNTHASE) (ALAD) (ALADH) 0.0207 0.074 0.3847
Echinococcus granulosus sodium bile acid cotransporter 0.053 0.2072 0.2331
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0029 0.0009 0.0003
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0061 0.0138 0.0131
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Echinococcus granulosus fetal alzheimer antigen falz 0.006 0.0136 0.0152
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0869 0.0977
Echinococcus multilocularis L aminoadipate semialdehyde 0.0171 0.0592 0.0666
Brugia malayi GnHR receptor homolog 0.0047 0.0083 0.0119
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0087 0.0247 0.0277
Echinococcus granulosus caspase 3 0.008 0.0219 0.0246
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0384 0.1472 0.1466
Toxoplasma gondii aldose reductase, putative 0.0067 0.0165 0.0452
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Loa Loa (eye worm) hypothetical protein 0.0058 0.0129 0.0122
Loa Loa (eye worm) hypothetical protein 0.0051 0.0096 0.009
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0036 0.0035 0.0083
Mycobacterium ulcerans hypothetical protein 0.0046 0.0079 0.0135
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0083 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Echinococcus multilocularis transient receptor potential cation channel 0.0036 0.0035 0.0039
Trypanosoma cruzi aldo-keto reductase 0.0067 0.0165 0.0466
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0033 0.0024 0.0026
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0063 0.0056
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0136 0.0283
Schistosoma mansoni importin beta-1 0.0058 0.0129 0.0137
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0074 0.0155
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Mycobacterium ulcerans dehydrogenase 0.0036 0.0035 0.006
Echinococcus multilocularis jun protein 0.0353 0.1342 0.1509
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0229 0.1188
Leishmania major dehydrogenase-like protein 0.0036 0.0035 0.0098
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0046 0.0079 0.0081
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0047 0.0083 0.0119
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0023 0.0064
Brugia malayi RNA recognition motif domain containing protein 0.0516 0.2013 0.3146
Entamoeba histolytica hypothetical protein 0.0036 0.0035 0.0035
Echinococcus granulosus g protein coupled receptor 0.0047 0.0083 0.0093
Echinococcus multilocularis dna polymerase kappa 0.0085 0.0238 0.0268
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0248 0.0241
Loa Loa (eye worm) hypothetical protein 0.0069 0.0171 0.0164
Leishmania major DNA topoisomerase ii 0.0153 0.0518 0.1469
Echinococcus multilocularis nervana 2 0.01 0.0301 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0047
Brugia malayi hypothetical protein 0.0305 0.1143 0.1782
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Mycobacterium ulcerans DNA gyrase subunit A 0.0033 0.0025 0.0042
Schistosoma mansoni growth hormone secretagogue receptor 0.0047 0.0083 0.0085
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0019
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0875 0.0978
Mycobacterium ulcerans DNA polymerase IV 0.0085 0.0238 0.041
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0139 0.0462 0.1296
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0067 0.0166 0.0457
Echinococcus granulosus slit 2 protein 0.0051 0.0097 0.0109
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0097 0.0287 0.0801
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0384 0.1472 0.1656
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0051 0.0099 0.0172
Echinococcus multilocularis ETS transcription factor Elf 5 0.0034 0.0027 0.003
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0091 0.0261 0.0399
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0056 0.0754
Trichomonas vaginalis 6-phosphofructokinase, putative 0.006 0.0136 0.0283
Schistosoma mansoni chromobox protein 0.007 0.0177 0.0192
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0051 0.0099 0.0281
Brugia malayi F/Y-rich N-terminus family protein 0.006 0.0136 0.0203
Schistosoma mansoni caspase-7 (C14 family) 0.0029 0.0009 0.0002
Onchocerca volvulus 0.053 0.2072 0.4298
Leishmania major cytochrome p450-like protein 0.0087 0.0248 0.0703
Trypanosoma brucei cytochrome P450, putative 0.0087 0.0248 0.068
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0033 0.0024 0.005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0067 0.0166 0.0187
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0155 0.0148
Schistosoma mansoni neuropeptide f receptor 76f 0.0047 0.0083 0.0085
Echinococcus granulosus axis inhibition protein axin 0.006 0.0134 0.0151
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0056 0.0144
Schistosoma mansoni hypothetical protein 0.0041 0.0057 0.0057
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0103 0.0276
Trypanosoma cruzi protein farnesyltransferase, putative 0.0121 0.0388 0.1099
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0536 0.2095 0.2351
Echinococcus granulosus lysine specific demethylase 6a 0.0077 0.0205 0.0231
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0091 0.0261 0.0399
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0047 0.0083 0.0085
Onchocerca volvulus 0.0148 0.05 0.1022
Echinococcus granulosus nAChR subunit 0.0284 0.1057 0.1189
Schistosoma mansoni 6-phosphofructokinase 0.0223 0.0805 0.0899
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0042 0.0063 0.0071
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0046 0.0079 0.0207
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0207
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0035 0.006
Echinococcus granulosus Regulator of G protein signaling 20 0.006 0.0134 0.0151
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0083 0.0093
Echinococcus multilocularis fatty acid binding protein FABP2 0.0205 0.0732 0.0823
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0047 0.0083 0.0093
Onchocerca volvulus 0.0036 0.0035 0.0054
Trypanosoma brucei hypothetical protein, conserved 0.0214 0.077 0.2167
Trypanosoma cruzi cysteine peptidase, putative 0.0087 0.0247 0.07
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0035 0.006
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0067 0.0165 0.0343
Schistosoma mansoni ran 0.0043 0.0065 0.0066
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Echinococcus multilocularis somatostatin receptor 0.0047 0.0083 0.0093
Echinococcus multilocularis G protein coupled receptor 139 0.0047 0.0083 0.0093
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0207
Schistosoma mansoni jumonji domain containing protein 0.0044 0.0071 0.0072
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0029 0.0009 0.001
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0444 0.1719 0.8938
Toxoplasma gondii ABC1 family protein 0.0148 0.05 0.1405
Onchocerca volvulus 0.0047 0.0083 0.0154
Brugia malayi regulator of G-protein signaling egl-10 0.0069 0.0175 0.0263
Brugia malayi glutathione reductase 0.0195 0.0691 0.1072
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Echinococcus granulosus lysine specific demethylase 5A 0.013 0.0423 0.0476
Echinococcus multilocularis cathepsin L cysteine protease 0.0087 0.0247 0.0277
Onchocerca volvulus 0.0043 0.0064 0.0114
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Brugia malayi excitatory GABA receptor EXP-1A 0.0536 0.2095 0.3273
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0103 0.0313 0.0352
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0284 0.1057 0.1646
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Echinococcus multilocularis axis inhibition protein axin 0.006 0.0134 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0022 0.0047
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0023 0.0039
Brugia malayi EGF-like domain containing protein 0.0051 0.0097 0.0141
Trypanosoma brucei unspecified product 0.0039 0.005 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0071 0.0064
Trypanosoma cruzi hypothetical protein, conserved 0.0135 0.0445 0.1262
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0536 0.2095 0.2357
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0161 0.0552 0.0621
Onchocerca volvulus 0.0047 0.0083 0.0154
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0095 0.0278 0.0788
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0205 0.0733 0.2081
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0252 0.0926 0.1042
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.0623 0.2455 0.3837
Plasmodium vivax DNA gyrase subunit B, putative 0.0097 0.0287 0.0801
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.0128 0.0298
Brugia malayi hypothetical protein 0.0297 0.1113 0.1734
Echinococcus multilocularis aldo keto reductase 0.0067 0.0165 0.0185
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0051 0.0099 0.0171
Loa Loa (eye worm) hypothetical protein 0.0044 0.0068 0.0062
Loa Loa (eye worm) DNA topoisomerase I 0.0206 0.0738 0.0731
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0203 0.0725 0.0815
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0148 0.0496 0.0558
Loa Loa (eye worm) MH2 domain-containing protein 0.0379 0.1448 0.1442
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0036 0.0035 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0252 0.0926 0.1441
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0494 0.1923 0.3342
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0051 0.0099 0.0171
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0035 0.006
Mycobacterium tuberculosis Possible oxidoreductase 0.0036 0.0035 0.006
Schistosoma mansoni tar DNA-binding protein 0.0516 0.2013 0.2259
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Echinococcus granulosus caspase 0.0109 0.0339 0.0381
Trypanosoma cruzi DNA polymerase eta, putative 0.0057 0.0123 0.0347
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Loa Loa (eye worm) hypothetical protein 0.014 0.0465 0.0458
Loa Loa (eye worm) CXXC zinc finger family protein 0.0197 0.0701 0.0694
Brugia malayi CHD4 protein 0.0029 0.0008 0.0002
Echinococcus granulosus dnaJ subfamily B 0.1706 0.6914 0.778
Brugia malayi Nuclear hormone receptor-like 1 0.0203 0.0725 0.1126
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0086 0.0229
Onchocerca volvulus 0.0047 0.0083 0.0154
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0019
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Loa Loa (eye worm) LGC-31 protein 0.0536 0.2095 0.2089
Mycobacterium ulcerans carveol-like dehydrogenase 0.0036 0.0035 0.006
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.0568 0.2227 0.6316
Schistosoma mansoni biogenic amine receptor 0.0047 0.0083 0.0085
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Echinococcus granulosus sodium bile acid cotransporter 0.053 0.2072 0.2331
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0067 0.0165 0.0343
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0664 0.074
Schistosoma mansoni hypothetical protein 0.0031 0.0018 0.0012
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0112 0.0578
Brugia malayi MAP kinase sur-1 0.0104 0.0318 0.0488
Trichomonas vaginalis glycogen phosphorylase, putative 0.0114 0.0358 0.0746
Toxoplasma gondii heat shock protein 90, putative 0.0042 0.0062 0.016
Plasmodium falciparum heat shock protein 90 0.0042 0.0062 0.016
Brugia malayi hypothetical protein 0.0181 0.0635 0.0985
Loa Loa (eye worm) hypothetical protein 0.0058 0.0128 0.0122
Mycobacterium tuberculosis Probable reductase 0.0444 0.1719 0.2987
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Schistosoma mansoni ATP-citrate synthase 0.0045 0.0074 0.0076
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0536 0.2095 0.3273
Trichomonas vaginalis penicillin-binding protein, putative 0.0148 0.05 0.1039
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0083 0.0085
Echinococcus multilocularis lysine specific demethylase 5A 0.0112 0.035 0.0394
Giardia lamblia Reductase, putative 0.0036 0.0035 0.0096
Loa Loa (eye worm) hypothetical protein 0.006 0.0134 0.0127
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0051 0.0099 0.0172
Loa Loa (eye worm) hypothetical protein 0.0203 0.0725 0.0719
Echinococcus granulosus jumonji domain containing 1A 0.0044 0.0071 0.008
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0035 0.006
Echinococcus multilocularis ETS transcription factor Elf 2 0.0034 0.0027 0.003
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Brugia malayi larval opioid receptor 0.0047 0.0083 0.0119
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0386 0.148 0.1665
Giardia lamblia Rab geranylgeranyltransferase 0.0135 0.0445 0.1242
Trypanosoma cruzi heat shock protein 85, putative 0.0042 0.0062 0.0175
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0051 0.0099 0.0171
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0117 0.037 0.1049
Brugia malayi hypothetical protein 0.0252 0.0926 0.1441
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Loa Loa (eye worm) DR-78 0.0181 0.0635 0.0629
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Schistosoma mansoni axis inhibition protein axin 0.006 0.0134 0.0143
Leishmania major short chain dehydrogenase/reductase, putative 0.0036 0.0035 0.0098
Trichomonas vaginalis glutathione reductase, putative 0.0067 0.0166 0.0346
Giardia lamblia DINP protein human, muc B family 0.0064 0.0151 0.0422
Brugia malayi Bromodomain containing protein 0.009 0.0259 0.0395
Onchocerca volvulus 0.0536 0.2095 0.4346
Mycobacterium leprae conserved hypothetical protein 0.0148 0.05 0.2597
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Brugia malayi glucose-6-phosphate dehydrogenase 0.0882 0.3522 0.5512
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0083 0.0093
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0536 0.2095 0.2357
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0135 0.0445 0.05
Brugia malayi Bromodomain containing protein 0.0179 0.0626 0.097
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0087 0.0247 0.0514
Toxoplasma gondii hypothetical protein 0.0054 0.011 0.0296
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0117 0.037 0.1027
Brugia malayi acetyltransferase, GNAT family protein 0.0461 0.1789 0.2795
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0875 0.0978
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Brugia malayi G-protein coupled receptor 0.0047 0.0083 0.0119
Schistosoma mansoni neuropeptide receptor 0.0047 0.0083 0.0085
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0104 0.0315 0.0308
Loa Loa (eye worm) beta-lactamase 0.0148 0.05 0.0493
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0444 0.1719 0.2987
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0051 0.0099 0.0171
Brugia malayi hypothetical protein 0.0203 0.0725 0.1126
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0036 0.0035 0.0098
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.01 0.0301 0.0331
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.005 0.0086
Schistosoma mansoni organic anion transporter 0.0029 0.0009 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0313 0.0345
Loa Loa (eye worm) cytochrome P450 0.0051 0.0099 0.0092
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0384 0.1472 0.1656
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0046 0.0079 0.0088
Loa Loa (eye worm) hypothetical protein 0.0099 0.0297 0.029
Echinococcus multilocularis heat shock protein 0.0042 0.0062 0.0069
Leishmania major cathepsin L-like protease 0.0331 0.1254 0.3559
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0043 0.0067 0.006
Loa Loa (eye worm) hypothetical protein 0.0203 0.0725 0.0719
Entamoeba histolytica aldose reductase, putative 0.0067 0.0165 0.04
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0083 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0035 0.0039
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0023 0.0025
Leishmania major oxidoreductase-like protein 0.0036 0.0035 0.0098
Schistosoma mansoni hypothetical protein 0.0041 0.0057 0.0057
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0882 0.3522 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0087 0.0247 0.024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0016
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0232 0.0846 0.0839
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0163
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0023 0.0049
Schistosoma mansoni ran 0.0043 0.0065 0.0066
Entamoeba histolytica hypothetical protein 0.0284 0.1057 0.2908
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0095 0.0278 0.0425
Mycobacterium ulcerans ketoacyl reductase 0.0036 0.0035 0.006
Toxoplasma gondii phosphofructokinase PFKII 0.006 0.0136 0.0371
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0103 0.0267
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0046 0.0079 0.0163
Trypanosoma brucei DNA polymerase IV, putative 0.0078 0.021 0.0571
Echinococcus granulosus retinol dehydrogenase 11 0.0036 0.0035 0.0039
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0128 0.0267
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Schistosoma mansoni coup transcription factor 0.0384 0.1472 0.165
Loa Loa (eye worm) ATP-citrate synthase 0.0053 0.0108 0.0101
Echinococcus granulosus cathepsin L cysteine proteinase 0.0087 0.0247 0.0277
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0067 0.0166 0.0457
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0181 0.0635 0.0715
Echinococcus granulosus phd:f box containing protein 0.0044 0.0071 0.008
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0882 0.3522 0.7328
Entamoeba histolytica rodhanase-like domain containing protein 0.0062 0.0146 0.0346
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Leishmania major prostaglandin f synthase, putative 0.0067 0.0165 0.0466
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0384 0.1472 0.1466
Brugia malayi A-kinase anchor protein 10, precursor 0.006 0.0134 0.02
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0145 0.0155
Toxoplasma gondii hypothetical protein 0.0135 0.0445 0.1249
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0643 0.1109
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0036 0.0035 0.0098
Brugia malayi Retinol dehydrogenase 12 0.0036 0.0035 0.0044
Toxoplasma gondii aminopeptidase N, putative 0.0329 0.1242 0.3515
Schistosoma mansoni neuropeptide receptor 0.0047 0.0083 0.0085
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.0538 0.1505
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0303 0.0333
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0236 0.0265
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0536 0.2095 0.2357
Brugia malayi PXA domain containing protein 0.006 0.0134 0.02
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0223 0.0805 0.1399
Schistosoma mansoni biogenic amine receptor 0.0047 0.0083 0.0085
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0097 0.0287 0.0499
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0036 0.0035 0.0074
Echinococcus multilocularis ubiquitin specific protease 41 0.0084 0.0236 0.0265
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0236 0.0668
Echinococcus granulosus expressed conserved protein 0.0093 0.0272 0.0305
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Schistosoma mansoni neuropeptide receptor 0.0047 0.0083 0.0085
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0035 0.006
Mycobacterium ulcerans short-chain dehydrogenase 0.0036 0.0035 0.006
Brugia malayi Rhodanese-like domain containing protein 0.0062 0.0146 0.0217
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0181 0.0635 0.0708
Echinococcus multilocularis cathepsin L 0.0045 0.0073 0.0082
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0083 0.0076
Echinococcus multilocularis fmrfamide receptor 0.0047 0.0083 0.0093
Schistosoma mansoni DNA topoisomerase type I 0.0206 0.0738 0.0823
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0384 0.1472 0.165
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Echinococcus granulosus retinoic acid receptor rxr beta a 0.069 0.2733 0.3074
Brugia malayi Steroid receptor seven-up type 2 0.0384 0.1472 0.2297
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0536 0.2095 0.3273
Schistosoma mansoni glycogen phosphorylase 0.0049 0.0092 0.0095
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.0238 0.0676
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Trypanosoma brucei protein kinase, putative 0.0104 0.0318 0.088
Echinococcus granulosus lamin 0.0142 0.0473 0.0532
Echinococcus granulosus histone acetyltransferase KAT2B 0.0444 0.1717 0.1931
Schistosoma mansoni nuclear receptor 0.0181 0.0635 0.0708
Loa Loa (eye worm) PXA domain-containing protein 0.006 0.0134 0.0127
Brugia malayi Regulator of G protein signaling domain containing protein 0.006 0.0134 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0236 0.049
Chlamydia trachomatis DNA gyrase subunit B 0.0097 0.0287 0.075
Schistosoma mansoni glycogen phosphorylase 0.0114 0.0358 0.0396
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0069 0.0171 0.0192
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0536 0.2095 0.2357
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0171 0.0592 0.0585
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0069 0.0172 0.0473
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0576 0.2262 0.3899
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0087 0.0247 0.0514
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0062 0.0142 0.0152
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Echinococcus multilocularis neuropeptide FF receptor 2 0.0047 0.0083 0.0093
Brugia malayi Synaptic glycoprotein SC2 0.0046 0.0079 0.0112
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0536 0.2095 0.3273
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.0318 0.0889
Echinococcus multilocularis nervana 2 0.0062 0.0142 0.0159
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0163
Onchocerca volvulus 0.0047 0.0083 0.0154
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0048 0.0086 0.0148
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0536 0.2095 0.2357
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Echinococcus multilocularis nAChR subunit 0.0536 0.2095 0.2357
Brugia malayi beta-lactamase 0.0148 0.05 0.0772
Onchocerca volvulus 0.0047 0.0083 0.0154
Echinococcus multilocularis snurportin 1 0.0623 0.2453 0.276
Trypanosoma brucei lanosterol synthase 0.0133 0.0436 0.1216
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.024 0.0875 0.0869
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0135 0.0445 0.1262
Echinococcus multilocularis dnaJ subfamily B 0.1706 0.6914 0.778
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0318 0.0662
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0062 0.0146 0.0303
Trichomonas vaginalis phosphofructokinase, putative 0.0223 0.0805 0.1675
Entamoeba histolytica deoxycytidyl transferase, putative 0.0057 0.0123 0.0281
Loa Loa (eye worm) hypothetical protein 0.0139 0.0462 0.0456
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0623 0.2453 0.2448
Schistosoma mansoni tar DNA-binding protein 0.0516 0.2013 0.2259
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Mycobacterium ulcerans hypothetical protein 0.1435 0.58 1
Trypanosoma cruzi hypothetical protein, conserved 0.0148 0.05 0.1417
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0155 0.0232
Brugia malayi TAR-binding protein 0.0516 0.2013 0.3146
Echinococcus multilocularis protein patched 0.0043 0.0064 0.0071
Loa Loa (eye worm) hypothetical protein 0.053 0.2072 0.2066
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0067 0.0166 0.0187
Echinococcus granulosus nervana 2 0.01 0.0301 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0134 0.0279
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0076 0.0202 0.0195
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0222 0.0803 0.0903
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0067 0.0165 0.0855
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0047 0.0083 0.0119
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0051 0.0099 0.0171
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.0035 0.0083
Echinococcus multilocularis beta adrenergic receptor kinase 0.0061 0.0138 0.0155
Loa Loa (eye worm) hypothetical protein 0.0058 0.0128 0.0122
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0392 0.1505 0.4263
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0036 0.0035 0.0039
Trypanosoma cruzi DNA topoisomerase II, putative 0.0153 0.0518 0.1469
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0064 0.0071
Schistosoma mansoni ets-related 0.0706 0.2795 0.314
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.024 0.0875 0.1362
Onchocerca volvulus 0.0091 0.0261 0.0526
Schistosoma mansoni heat shock protein 0.0042 0.0062 0.0062
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Echinococcus granulosus snurportin 1 0.0623 0.2453 0.276
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0067 0.0166 0.018
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) 6-phosphofructokinase 0.0223 0.0805 0.0799
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Echinococcus multilocularis cysteine protease 0.0087 0.0247 0.0277
Brugia malayi Papain family cysteine protease containing protein 0.0087 0.0247 0.0376
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0063 0.013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0036 0.0035 0.0083
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.005 0.0105
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0502 0.0565
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0353 0.1342 0.1509
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0148 0.05 0.0868
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0047 0.0083 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0384 0.1472 0.2297
Entamoeba histolytica Ran family GTPase 0.0043 0.0065 0.012
Entamoeba histolytica hypothetical protein 0.0046 0.0079 0.0158
Loa Loa (eye worm) hypothetical protein 0.0203 0.0725 0.0719
Echinococcus multilocularis ecdysone induced protein 78C 0.0384 0.1472 0.1656
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0067 0.0166 0.2246
Echinococcus granulosus glycine receptor subunit alpha 1 0.0536 0.2095 0.2357
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0121 0.0388 0.1086
Toxoplasma gondii aminopeptidase N protein 0.0329 0.1242 0.3515
Schistosoma mansoni hypothetical protein 0.0051 0.0099 0.0104
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0035 0.0039
Echinococcus granulosus nervana 2 0.01 0.0301 0.0338
Echinococcus granulosus glycogen phosphorylase 0.0114 0.0358 0.0403
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0129 0.0341
Brugia malayi G-protein coupled receptor 0.0047 0.0083 0.0119
Entamoeba histolytica DNA topoisomerase II, putative 0.0161 0.0552 0.1488
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0165 0.0247
Brugia malayi cytochrome P450 0.0051 0.0099 0.0145
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Mycobacterium ulcerans hypothetical protein 0.0148 0.05 0.0861
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0236 0.0668
Trypanosoma brucei ISWI complex protein 0.0031 0.0018 0.0025
Brugia malayi Cytochrome P450 family protein 0.0087 0.0248 0.0378
Brugia malayi heat shock protein 90 0.0042 0.0062 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0006 0.0015
Brugia malayi Inositol-1 0.0041 0.0056 0.0077
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Echinococcus granulosus tachykinin peptides receptor 99D 0.0047 0.0083 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Leishmania major hypothetical protein, conserved 0.0036 0.0035 0.0098
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0056 0.0117
Echinococcus multilocularis retinol dehydrogenase 13 0.0036 0.0035 0.0039
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0036 0.0035 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Trichomonas vaginalis heat shock protein, putative 0.0027 0 0.0001
Echinococcus granulosus hypothetical protein 0.0047 0.0083 0.0093
Mycobacterium tuberculosis Conserved hypothetical protein 0.0175 0.0611 0.1061
Schistosoma mansoni phd/f-box containing protein 0.0044 0.0071 0.0072
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0052 0.0101 0.0113
Toxoplasma gondii exonuclease III APE 0.0117 0.037 0.1035
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0051 0.0099 0.0172
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 1
Mycobacterium ulcerans hypothetical protein 0.0175 0.0611 0.1053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0948 0.3793 0.6592
Wolbachia endosymbiont of Brugia malayi delta-aminolevulinic acid dehydratase 0.0207 0.074 1
Echinococcus granulosus protein C ets 2 0.0034 0.0027 0.003
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Trypanosoma cruzi ISWI complex protein 0.0031 0.0018 0.005
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0444 0.1719 0.2987
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0384 0.1472 0.2297
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0142 0.0473 0.0467
Echinococcus multilocularis orexin receptor type 2 0.0047 0.0083 0.0093
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0065 0.0169
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0536 0.2095 0.2357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0536 0.2095 0.2089
Schistosoma mansoni zinc finger protein 0.0031 0.0018 0.0012
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0229 0.0634
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0536 0.2095 0.2351
Onchocerca volvulus 0.0091 0.0261 0.0526
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Schistosoma mansoni transmemberane protein 0.01 0.0301 0.0331
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0033 0.0024 0.0026
Trypanosoma brucei DNA topoisomerase ii 0.018 0.063 0.1767
Brugia malayi Uncoordinated protein 44 0.0043 0.0067 0.0094
Loa Loa (eye worm) hypothetical protein 0.0087 0.0247 0.024
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0047 0.0083 0.0076
Mycobacterium tuberculosis Probable delta-aminolevulinic acid dehydratase HemB (porphobilinogen synthase) (ALAD) (ALADH) 0.0105 0.0322 0.0559
Trichomonas vaginalis ap endonuclease, putative 0.0117 0.037 0.0769
Echinococcus granulosus ETS transcription factor Elf 1 0.0034 0.0027 0.003
Schistosoma mansoni DNA topoisomerase II 0.0161 0.0552 0.0614
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0051 0.0099 0.0172
Brugia malayi Dopamine receptor 0.0047 0.0083 0.0119
Echinococcus multilocularis dro:myosuppressin receptor 0.0047 0.0083 0.0093
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Schistosoma mansoni thyroid hormone receptor 0.0771 0.3063 0.3442
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0135 0.0445 0.05
Leishmania major cytochrome p450-like protein 0.0051 0.0099 0.0281
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Brugia malayi Protein kinase domain containing protein 0.0044 0.0071 0.01
Brugia malayi polk-prov protein 0.0046 0.0077 0.011
Schistosoma mansoni cytochrome P450 0.0051 0.0099 0.0104
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0046 0.0079 0.0158
Schistosoma mansoni protein phosphatase 2C 0.0044 0.0071 0.0072
Onchocerca volvulus 0.0197 0.0701 0.1442
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0134 0.0279
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0643 0.1109
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0297 0.1113 0.1252
Entamoeba histolytica hypothetical protein 0.006 0.0134 0.0314
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0384 0.1472 0.2297
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0223 0.0805 0.2267
Echinococcus granulosus heat shock protein 0.0042 0.0062 0.0069
Brugia malayi Receptor family ligand binding region containing protein 0.0122 0.039 0.0601
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Leishmania major metacaspase, putative 0.0029 0.0009 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Brugia malayi Serotonin receptor 0.0047 0.0083 0.0119
Loa Loa (eye worm) nuclear receptor NHR-67 0.0181 0.0635 0.0629
Schistosoma mansoni tar DNA-binding protein 0.0516 0.2013 0.2259
Schistosoma mansoni tar DNA-binding protein 0.0516 0.2013 0.2259
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0536 0.2095 0.2351
Brugia malayi Cathepsin L-like precursor 0.0058 0.0128 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0073 0.0152
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0203 0.0725 0.0815
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0882 0.3522 0.3963
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0074 0.0155
Echinococcus granulosus thioredoxin glutathione reductase 0.0195 0.0691 0.0777
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0203 0.0725 0.0719
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Echinococcus multilocularis regulator of G protein signaling 7 0.0069 0.0175 0.0196
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0384 0.1472 0.1656
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0033 0.0025 0.0332
Entamoeba histolytica aldose reductase, putative 0.0067 0.0165 0.04
Loa Loa (eye worm) hypothetical protein 0.0148 0.05 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0051 0.0099 0.0172
Plasmodium vivax SET domain protein, putative 0.0153 0.052 0.1462
Mycobacterium tuberculosis Conserved protein 0.0148 0.05 0.0868
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0056 0.0134
Leishmania major geranylgeranyltransferase, putative 0.0033 0.0024 0.0067
Schistosoma mansoni hypothetical protein 0.0065 0.0155 0.0167
Brugia malayi hypothetical protein 0.006 0.0134 0.02
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0084 0.0236 0.0599
Entamoeba histolytica glycogen phosphorylase, putative 0.0114 0.0358 0.0944
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Loa Loa (eye worm) ACC-1 protein 0.0536 0.2095 0.2089
Onchocerca volvulus 0.0087 0.0247 0.0496
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0097 0.0287 0.3879
Brugia malayi follicle stimulating hormone receptor 0.075 0.2977 0.4656
Echinococcus granulosus death domain containing protein 0.0043 0.0067 0.0075
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0394
Onchocerca volvulus 0.0181 0.0635 0.1305
Schistosoma mansoni carbonyl reductase 0.0036 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0062 0.0146 0.0163
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0069 0.0175 0.0168
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0222
Brugia malayi tailless protein 0.0181 0.0635 0.0985
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0129 0.0144
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Entamoeba histolytica cysteine proteinase, putative 0.0045 0.0073 0.0142
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.006 0.0136 0.0379
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0095 0.0278 0.0479
Schistosoma mansoni regulator of G protein signaling 0.006 0.0134 0.0143
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0536 0.2095 0.2357
Onchocerca volvulus 0.0107 0.0329 0.0668
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0882 0.3522 0.7328
Schistosoma mansoni carbonyl reductase 0.0036 0.0035 0.0032
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0033 0.0029
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0121 0.0388 0.1078
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0046 0.0079 0.0158
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0042 0.0063 0.0071
Schistosoma mansoni cell polarity protein 0.0051 0.0096 0.0101
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0036 0.0035 0.018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0188 0.0664 0.074
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0035 0.0098
Brugia malayi nuclear receptor NHR-67 0.0181 0.0635 0.0985
Toxoplasma gondii cathepsin CPL 0.0087 0.0247 0.0686
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0536 0.2095 0.2357
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0153 0.0518 0.1448
Echinococcus multilocularis muscleblind protein 0.0149 0.0502 0.0565
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0033 0.0024 0.0052
Trypanosoma cruzi metacaspase, putative 0.0029 0.0009 0.0024
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0036 0.0035 0.0035
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0122 0.039 0.0384
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0205 0.0733 0.0825
Brugia malayi Dehydrogenases, short chain protein 2 0.0036 0.0035 0.0044
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0062 0.0146 0.0303
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0135 0.0445 0.1241
Brugia malayi hypothetical protein 0.0181 0.0635 0.0985
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0536 0.2095 0.2089
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0123 0.0181
Onchocerca volvulus 0.0036 0.0035 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0051 0.0099 0.0172
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Echinococcus multilocularis expressed protein 0.1162 0.4675 0.526
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Loa Loa (eye worm) melatonin receptor type 1A 0.0047 0.0083 0.0076
Echinococcus granulosus fatty acid binding protein FABP2 0.0205 0.0732 0.0823
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0267 0.0988 0.1105
Onchocerca volvulus 0.0047 0.0083 0.0154
Echinococcus multilocularis 6 phosphofructokinase 0.0223 0.0805 0.0906
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0088 0.0252 0.0701
Echinococcus granulosus G protein coupled receptor 139 0.0047 0.0083 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Echinococcus multilocularis Ankyrin 0.0044 0.0068 0.0077
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.05 0.1039
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0036 0.0035 0.0035
Brugia malayi nuclear receptor NHR-88 0.0384 0.1472 0.2297
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0079 0.0198
Schistosoma mansoni bromodomain containing protein 0.0155 0.0527 0.0585
Echinococcus granulosus caspase 8 0.0029 0.0009 0.001
Schistosoma mansoni hypothetical protein 0.1706 0.6914 0.7778
Echinococcus multilocularis conserved hypothetical protein 0.0036 0.0035 0.0039
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Schistosoma mansoni transcription factor LCR-F1 0.0297 0.1113 0.1245
Loa Loa (eye worm) dehydrogenase 0.0036 0.0035 0.0028
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0113 0.012
Schistosoma mansoni adenoreceptor 0.0047 0.0083 0.0085
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0117 0.037 0.1035
Echinococcus granulosus Glycosyl transferase family 35 0.0114 0.0358 0.0403
Brugia malayi Cytochrome P450 family protein 0.015 0.0506 0.0783
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0882 0.3522 0.3518
Mycobacterium leprae Probable lipase LipE 0.0148 0.05 0.2597
Loa Loa (eye worm) steroid hormone receptor 0.0384 0.1472 0.1466
Mycobacterium tuberculosis Probable lipase LipE 0.0148 0.05 0.0868
Echinococcus multilocularis GA binding protein alpha chain 0.0232 0.0846 0.0951
Schistosoma mansoni hypothetical protein 0.0156 0.0533 0.0592
Onchocerca volvulus 0.0047 0.0083 0.0154
Schistosoma mansoni sodium-bile acid cotransporter 0.0263 0.0971 0.1086
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0083 0.0173
Brugia malayi Cathepsin L-like precursor 0.0087 0.0247 0.0376
Brugia malayi Endoplasmin precursor 0.0042 0.0062 0.0087
Echinococcus granulosus Nuclear hormone receptor HR96 0.0181 0.0635 0.0715
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0229 0.0634
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Leishmania major hypothetical protein, conserved 0.0044 0.0071 0.0201
Loa Loa (eye worm) hypothetical protein 0.0065 0.0155 0.0148
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0643 0.1109
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0136 0.0283
Schistosoma mansoni nuclear hormone receptor 0.0181 0.0635 0.0708
Schistosoma mansoni endoplasmin 0.0042 0.0062 0.0062
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0103 0.0276
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0036 0.0035 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Echinococcus granulosus neuropeptide FF receptor 2 0.0047 0.0083 0.0093
Entamoeba histolytica rodhanase-like domain containing protein 0.0062 0.0146 0.0346
Schistosoma mansoni neurotransmitter gated ion channel 0.0284 0.1057 0.1182
Echinococcus multilocularis beta LACTamase domain containing family member 0.0148 0.05 0.0562
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0083 0.0093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0384 0.1472 0.2297
Mycobacterium ulcerans 6-phosphofructokinase 0.0223 0.0805 0.1388
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0009 0.0003
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi G protein-coupled receptor 0.0047 0.0083 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.006 0.0134 0.0143
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0083 0.0173
Onchocerca volvulus 0.0067 0.0165 0.0324
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0067 0.0166 0.0472
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0148 0.05 0.0868
Brugia malayi Sodium Bile acid symporter family protein 0.053 0.2072 0.3237
Plasmodium falciparum histone acetyltransferase GCN5 0.0123 0.0395 0.1108
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0045 0.0073 0.0074
Schistosoma mansoni hypothetical protein 0.0047 0.0083 0.0085
Echinococcus multilocularis ewsr:fli fusion protein type 0.0034 0.0027 0.003
Echinococcus multilocularis neurogenic locus notch protein 0.0051 0.0096 0.0108
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Leishmania major short chain dehydrogenase, putative 0.0036 0.0035 0.0098
Echinococcus granulosus cathepsin L cysteine protease 0.0045 0.0073 0.0082
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0074 0.0155
Toxoplasma gondii oxidoreductase, putative 0.0036 0.0035 0.0083
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0036 0.0035 0.0032
Schistosoma mansoni survival motor neuron protein 0.0049 0.0088 0.0092
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0083 0.0085
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0035 0.0039
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0036 0.0035 0.0039
Brugia malayi Cathepsin L-like cysteine proteinase 0.0058 0.0128 0.019
Plasmodium vivax vivapain-2 0.0087 0.0247 0.0686
Echinococcus granulosus dro:myosuppressin receptor 0.0047 0.0083 0.0093
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0136 0.0283
Echinococcus granulosus tar DNA binding protein 0.0516 0.2013 0.2265
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0643 0.0717
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.0318 0.0902
Schistosoma mansoni ets 0.0034 0.0027 0.0023
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0252 0.0926 0.1441
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0085 0.0238 0.0496
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0392 0.1505 0.1693
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.01 0.0301 0.0338
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0087 0.0247 0.024
Schistosoma mansoni amine GPCR 0.0047 0.0083 0.0085
Echinococcus granulosus cathepsin l cysteine peptidase 0.0087 0.0247 0.0277
Entamoeba histolytica cysteine proteinase, putative 0.0045 0.0073 0.0142
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Brugia malayi ATP-citrate synthase 0.0053 0.0108 0.0158
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.0318 0.0902
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0071 0.0201
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0284 0.1057 0.1182
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Schistosoma mansoni hypothetical protein 0.0041 0.0057 0.0057
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.006 0.0134 0.0143
Echinococcus granulosus ecdysone induced protein 78C 0.0384 0.1472 0.1656
Giardia lamblia Hypothetical protein 0.0036 0.0035 0.0096
Loa Loa (eye worm) hypothetical protein 0.006 0.0134 0.0127
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0386 0.148 0.1665
Loa Loa (eye worm) ShTK domain-containing protein 0.0091 0.0261 0.0255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Mycobacterium ulcerans lipase LipD 0.0148 0.05 0.0861
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0318 0.0351
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0536 0.2095 0.2089
Leishmania major mitochondrial DNA topoisomerase II 0.018 0.063 0.1787
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0384 0.1472 0.1656
Trypanosoma cruzi trypanothione reductase, putative 0.0067 0.0166 0.0472
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Onchocerca volvulus 0.0384 0.1472 0.3048
Echinococcus granulosus nervana 2 0.0062 0.0142 0.0159
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.004 0.0053 0.0276
Schistosoma mansoni jumonji/arid domain-containing protein 0.013 0.0423 0.0469
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0033 0.0024 0.0004
Schistosoma mansoni retinoic acid receptor RXR 0.069 0.2733 0.3069
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0036 0.0035 0.0054
Mycobacterium ulcerans oxidoreductase 0.0036 0.0035 0.006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0117 0.037 0.1035
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0023 0.0039
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0056 0.0095
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0229 0.0634
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0009 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0136 0.0283
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0047 0.0083 0.0093
Giardia lamblia Prenyltransferase 0.0121 0.0388 0.1082
Echinococcus granulosus nuclear factor of activated T cells 5 0.0222 0.0803 0.0903
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0047 0.0083 0.0093
Brugia malayi hypothetical protein 0.0238 0.0869 0.1351
Plasmodium falciparum polyprenol reductase, putative 0.0046 0.0079 0.0207
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0112 0.0125
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Onchocerca volvulus 0.1194 0.4808 1
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0033 0.0024 0.0017
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0048 0.0086 0.1162
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Toxoplasma gondii hypothetical protein 0.0257 0.0948 0.2681
Onchocerca volvulus 0.0171 0.0592 0.1215
Schistosoma mansoni hypothetical protein 0.0047 0.0083 0.0085
Echinococcus granulosus Nuclear hormone receptor HR96 0.0181 0.0635 0.0715
Plasmodium vivax hypothetical protein, conserved 0.0148 0.05 0.1405
Loa Loa (eye worm) hypothetical protein 0.0199 0.0707 0.0701
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0051 0.0099 0.0257
Schistosoma mansoni hypothetical protein 0.014 0.0465 0.0515
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0036 0.0035 0.006
Echinococcus granulosus oxidoreductase 0.0036 0.0035 0.0039
Giardia lamblia NADH oxidase lateral transfer candidate 0.0067 0.0166 0.0464
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0145 0.0162
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0136 0.0318
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0181 0.0635 0.1305
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0083 0.0093
Brugia malayi ImpB/MucB/SamB family protein 0.0057 0.0123 0.0181
Toxoplasma gondii histone lysine methyltransferase SET1 0.0303 0.1137 0.3218
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0181 0.0635 0.0715
Brugia malayi Tachykinin-like peptides receptor 99D 0.0047 0.0083 0.0119
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0036 0.0035 0.0098
Plasmodium falciparum DNA gyrase subunit A 0.0033 0.0025 0.0055
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0252 0.0926 0.092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0083 0.0085
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0084 0.0236 0.0265
Schistosoma mansoni gabp alpha 0.0232 0.0846 0.0945
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0284 0.1057 0.1646
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0051 0.0099 0.0171
Leishmania major aldo-keto reductase-like protein 0.0067 0.0165 0.0466
Trichomonas vaginalis phosphofructokinase, putative 0.0223 0.0805 0.1675
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0318 0.0902
Toxoplasma gondii heat shock protein HSP90 0.0042 0.0062 0.016
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0139 0.0462 0.1296
Brugia malayi Probable DNA topoisomerase II 0.0161 0.0552 0.0854
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.006 0.0134 0.0151
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0067 0.0166 0.0286
Brugia malayi CXXC zinc finger family protein 0.0197 0.0701 0.1088
Leishmania major hypothetical protein, conserved 0.0036 0.0035 0.0098
Echinococcus multilocularis retinol dehydrogenase 11 0.0036 0.0035 0.0039
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0006 0.0028
Schistosoma mansoni aldo-keto reductase 0.0067 0.0165 0.0178
Trypanosoma cruzi lanosterol synthase, putative 0.0133 0.0436 0.1237
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0135 0.0445 0.0687
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0139 0.0462 0.096
Schistosoma mansoni neurotransmitter gated ion channel 0.0252 0.0926 0.1035
Loa Loa (eye worm) cytochrome P450 family protein 0.015 0.0506 0.05
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.0731 0.1136
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0056 0.0158
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0875 0.0985
Onchocerca volvulus 0.0047 0.0083 0.0154
Onchocerca volvulus 0.0036 0.0035 0.0054
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0121 0.0388 0.0806
Trypanosoma cruzi cysteine peptidase, putative 0.0045 0.0073 0.0206
Onchocerca volvulus 0.0252 0.0926 0.1911
Echinococcus multilocularis caspase 0.0109 0.0339 0.0381
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0045 0.0073 0.0074
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0051 0.0099 0.0172
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0023 0.0025
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0297 0.077
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0023 0.0049
Echinococcus multilocularis zinc finger protein 0.0065 0.0157 0.0176
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0064 0.0071
Echinococcus multilocularis cysteine protease 0.0087 0.0247 0.0277
Loa Loa (eye worm) hypothetical protein 0.0055 0.0113 0.0106
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0297 0.0333
Echinococcus multilocularis ets variant gene 4 0.0034 0.0027 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0074 0.0155
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 0.6072
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Echinococcus multilocularis regulator of G protein signaling 0.006 0.0134 0.0151
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0083
Echinococcus granulosus Ankyrin 0.0044 0.0068 0.0077
Schistosoma mansoni amine GPCR 0.0047 0.0083 0.0085
Echinococcus granulosus regulator of G protein signaling 3 0.006 0.0134 0.0151
Echinococcus granulosus glycine receptor subunit beta 0.0536 0.2095 0.2357
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0036 0.0035 0.006
Brugia malayi Pre-SET motif family protein 0.0153 0.052 0.0804
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Onchocerca volvulus 0.0047 0.0083 0.0154
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0318 0.0902
Echinococcus granulosus neuropeptide receptor 0.0047 0.0083 0.0093
Brugia malayi steroid hormone receptor 0.0384 0.1472 0.2297
Trypanosoma cruzi heat shock protein 85, putative 0.0042 0.0062 0.0175
Loa Loa (eye worm) inositol-1 0.0041 0.0056 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0205 0.0733 0.2061
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.0083 0.0076
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0034 0.0027 0.002
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0051 0.0099 0.0171
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0165 0.0567 0.0631
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0036 0.0035 0.0039
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0029 0.0009 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0248 0.0703
Brugia malayi hypothetical protein 0.0034 0.0027 0.0031
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0035 0.0039
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0009 0.0009
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0536 0.2095 0.3273
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0036 0.0035 0.006
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0153 0.0518 0.1448
Brugia malayi Cathepsin L-like precursor 0.0087 0.0247 0.0376
Brugia malayi ORL1-like opioid receptor 0.0047 0.0083 0.0119
Onchocerca volvulus 0.0049 0.0088 0.0165
Mycobacterium ulcerans short chain dehydrogenase 0.1424 0.5754 0.992
Brugia malayi RE15519p 0.0047 0.0083 0.0119
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0107 0.0329 0.0506
Schistosoma mansoni inositol monophosphatase 0.0041 0.0056 0.0055
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0195 0.0691 0.12
Schistosoma mansoni nuclear receptor nhr-48 0.0181 0.0635 0.0708
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0384 0.1472 0.2297
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Schistosoma mansoni amine GPCR 0.0047 0.0083 0.0085
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0051 0.0099 0.0171
Onchocerca volvulus 0.0091 0.0261 0.0526
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0305 0.1143 0.1137
Echinococcus granulosus aldo keto reductase 0.0067 0.0165 0.0185
Schistosoma mansoni retinal dehydrogenase 0.0036 0.0035 0.0032
Mycobacterium ulcerans DNA gyrase subunit B 0.0097 0.0287 0.0495
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0064 0.0071
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Loa Loa (eye worm) TAR-binding protein 0.0516 0.2013 0.2008
Brugia malayi sulfakinin receptor protein 0.0047 0.0083 0.0119
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Onchocerca volvulus 0.0047 0.0083 0.0154
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0384 0.1472 0.2297
Plasmodium falciparum topoisomerase I 0.0206 0.0738 0.2081
Echinococcus multilocularis dna polymerase eta 0.0057 0.0123 0.0137
Loa Loa (eye worm) histone methyltransferase 0.0052 0.0101 0.0094
Brugia malayi Cation transporter family protein 0.0536 0.2095 0.3273
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0036 0.0035 0.0074
Echinococcus granulosus WW domain containing oxidoreductase 0.0036 0.0035 0.0039
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0223 0.0805 0.2285
Schistosoma mansoni hypothetical protein 0.0297 0.1113 0.1245
Onchocerca volvulus 0.0284 0.1057 0.2184
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0036 0.0035 0.006
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0071 0.0064
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma cruzi short chain dehydrogenase, putative 0.0036 0.0035 0.0098
Onchocerca volvulus 0.0305 0.1143 0.2364
Loa Loa (eye worm) transcription factor SMAD2 0.0379 0.1448 0.1442
Loa Loa (eye worm) hypothetical protein 0.0069 0.0175 0.0168
Leishmania major hypothetical protein, conserved 0.0036 0.0035 0.0098
Echinococcus multilocularis chromobox protein 1 0.007 0.0177 0.0199
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0074 0.0155
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.0083 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.077 0.2186
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0083 0.0235
Echinococcus multilocularis lamin 0.0142 0.0473 0.0532
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0333 0.126 0.3561
Echinococcus granulosus chromobox protein 1 0.007 0.0177 0.0199
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Echinococcus granulosus regulator of G protein signaling 3 0.006 0.0134 0.0151
Trichomonas vaginalis cdc25b, putative 0.0062 0.0146 0.0303
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.0318 0.0888
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0536 0.2095 0.3273
Schistosoma mansoni nAChR subunit 0.0252 0.0926 0.1035
Brugia malayi hypothetical protein 0.025 0.092 0.1431
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0045 0.0073 0.0206
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0023
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.3089
Echinococcus granulosus geminin 0.1951 0.7928 0.892
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0036 0.0035 0.0073
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0252 0.0926 0.1042
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0035 0.0098
Brugia malayi Cathepsin L-like precursor 0.0087 0.0247 0.0376
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Echinococcus multilocularis neuropeptide receptor 0.0047 0.0083 0.0093
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.0465 0.0718
Schistosoma mansoni chromobox protein 0.007 0.0177 0.0192
Trichomonas vaginalis heat shock protein, putative 0.0027 0 0.0001
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0023 0.0064
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Echinococcus multilocularis axis inhibition protein axin 0.006 0.0134 0.0151
Echinococcus multilocularis glycine receptor subunit beta 0.0536 0.2095 0.2357
Brugia malayi jmjC domain containing protein 0.0077 0.0205 0.0311
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0067 0.0166 0.0405
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0051 0.0099 0.0171
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0097 0.0287 0.0801
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0536 0.2095 0.3273
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0065 0.0184
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0067 0.0166 0.0472
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0135 0.0445 0.1262
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0297 0.0454
Schistosoma mansoni nuclear hormone receptor 0.0384 0.1472 0.165
Echinococcus granulosus histone acetyltransferase KAT2B 0.0139 0.0462 0.0519
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0461 0.1789 0.2013
Trypanosoma cruzi cysteine proteinase, putative 0.0045 0.0073 0.0206
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0104 0.0318 0.0311
Toxoplasma gondii thioredoxin reductase 0.0195 0.0691 0.1948
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0438 0.1692 0.8798
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0079 0.0163
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0536 0.2095 0.2357
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0036 0.0035 0.006
Echinococcus multilocularis caspase 3 0.008 0.0219 0.0246
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Trichomonas vaginalis chromobox protein, putative 0.007 0.0177 0.0369
Onchocerca volvulus 0.0252 0.0926 0.1911
Onchocerca volvulus 0.0087 0.0247 0.0496
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0117 0.037 0.0363
Echinococcus multilocularis jumonji domain containing 1A 0.0044 0.0071 0.008
Giardia lamblia Aldose reductase 0.0067 0.0165 0.0459
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0236 0.0265
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0103 0.029
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0112 0.0193
Brugia malayi Importin beta-1 subunit 0.0058 0.0129 0.0191
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0063 0.0112
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.0238 0.0676
Loa Loa (eye worm) hypothetical protein 0.0077 0.0205 0.0199
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0536 0.2095 0.3273
Trypanosoma cruzi hypothetical protein, conserved 0.0214 0.077 0.2186
Echinococcus granulosus hypothetical protein 0.0036 0.0035 0.0039
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0035 0.0074
Schistosoma mansoni histamine h1 receptor 0.0047 0.0083 0.0085
Echinococcus multilocularis tar DNA binding protein 0.0516 0.2013 0.2265
Trypanosoma brucei heat shock protein 90, putative 0.0042 0.0062 0.0151
Mycobacterium tuberculosis Probable dehydrogenase 0.0036 0.0035 0.006
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0067 0.0166 0.0457
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0536 0.2095 0.3273
Brugia malayi hypothetical protein 0.0203 0.0725 0.1126
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0086 0.022
Echinococcus granulosus g-protein coupled receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) ShTK domain-containing protein 0.0091 0.0261 0.0255
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0081 0.0206
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0023 0.0049
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0103 0.0313 0.0352
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0051 0.0099 0.0172
Echinococcus granulosus aldehyde reductase 0.0048 0.0085 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Loa Loa (eye worm) hypothetical protein 0.0054 0.011 0.0103
Giardia lamblia DNA topoisomerase II 0.0146 0.049 0.1368
Loa Loa (eye worm) hypothetical protein 0.007 0.0175 0.0168
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Echinococcus multilocularis protein dispatched 1 0.0049 0.0088 0.0099
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0086 0.0229
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Mycobacterium ulcerans ketoacyl reductase 0.0036 0.0035 0.006
Onchocerca volvulus 0.0047 0.0083 0.0154
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0034 0.0027 0.002
Entamoeba histolytica aldose reductase, putative 0.0067 0.0165 0.04
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0142 0.0473 0.0467
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi cathepsin L-like precursor 0.0058 0.0128 0.019
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0129 0.0341
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0047 0.0083 0.0085
Trypanosoma brucei heat shock protein 90, putative 0.0042 0.0062 0.0151
Schistosoma mansoni cathepsin F (C01 family) 0.0087 0.0247 0.027
Echinococcus multilocularis nervana 2 0.01 0.0301 0.0338
Echinococcus multilocularis microtubule associated protein 2 0.2184 0.8887 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Treponema pallidum exodeoxyribonuclease (exoA) 0.0117 0.037 0.1032
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0077 0.0193
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0203 0.0725 0.0809
Onchocerca volvulus 0.0047 0.0083 0.0154
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Echinococcus multilocularis steroid dehydrogenase 0.0036 0.0035 0.0039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0121 0.0388 0.0436
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0384 0.1472 0.1656
Brugia malayi Cation transporter family protein 0.0536 0.2095 0.3273
Loa Loa (eye worm) hypothetical protein 0.0058 0.0128 0.0122
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0318 0.0662
Schistosoma mansoni opsin-like receptor 0.0047 0.0083 0.0085
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0081 0.023
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0124 0.035
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0536 0.2095 0.2351
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0051 0.0099 0.0172
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0188 0.0664 0.0747
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0284 0.1057 0.1182
Trypanosoma cruzi metacaspase, putative 0.0029 0.0009 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0024 0.0067
Onchocerca volvulus 0.0277 0.1029 0.2126
Echinococcus granulosus allatostatin A receptor 0.0047 0.0083 0.0093
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0392 0.1505 0.1687
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0384 0.1472 0.165
Echinococcus granulosus neuropeptide s receptor 0.053 0.2073 0.2332
Trypanosoma cruzi cruzipain precursor, putative 0.0029 0.0007 0.0019
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0065 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.0083 0.0093
Trypanosoma cruzi metacaspase, putative 0.0029 0.0009 0.0024
Brugia malayi nuclear hormone receptor 0.0384 0.1472 0.2297
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0526 0.2053 0.2304
Loa Loa (eye worm) hypothetical protein 0.0148 0.05 0.0493
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0047 0.0083 0.0093
Leishmania major hypothetical protein, conserved 0.0036 0.0035 0.0098
Schistosoma mansoni lamin 0.0142 0.0473 0.0525
Trichomonas vaginalis aldo/keto reductase, putative 0.0067 0.0165 0.0343
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0036 0.0035 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0135 0.0445 0.1262
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0252 0.0926 0.1041
Echinococcus multilocularis pikachurin 0.0051 0.0096 0.0108
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0386 0.148 0.1665
Entamoeba histolytica acetyltransferase, GNAT family 0.0123 0.0395 0.1048
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.006 0.0134 0.0279
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.01 0.0301 0.0338
Onchocerca volvulus Protein ultraspiracle homolog 0.0384 0.1472 0.3048
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0036 0.0035 0.0032
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Echinococcus multilocularis ETS transcription factor Elf 2 0.0034 0.0027 0.003
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0386 0.148 0.1474
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0036 0.0035 0.0044
Echinococcus granulosus nervana 2 0.0062 0.0142 0.0159
Brugia malayi dehydrogenases, short chain protein 9 0.0036 0.0035 0.0044
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0083 0.0093
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0284 0.1057 0.1646
Echinococcus multilocularis glycogen phosphorylase 0.0114 0.0358 0.0403
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0036 0.0035 0.006
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0257
Echinococcus multilocularis thyroid hormone receptor alpha 0.0771 0.3063 0.3447
Schistosoma mansoni endoplasmin 0.0042 0.0062 0.0062
Schistosoma mansoni regulator of G protein signaling 0.0069 0.0175 0.0189
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0033 0.0024 0.0019
Trypanosoma cruzi ISWI complex protein 0.0031 0.0018 0.005
Loa Loa (eye worm) ACC-1 protein 0.0536 0.2095 0.2089
Loa Loa (eye worm) hypothetical protein 0.0091 0.0261 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0223 0.0805 0.1675
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Echinococcus multilocularis regulator of G protein signaling 3 0.006 0.0134 0.0151
Echinococcus multilocularis FTZ F1 alpha 0.0384 0.1472 0.1656
Toxoplasma gondii DNA topoisomerase 2, putative 0.0161 0.0552 0.1553
Echinococcus granulosus aldo keto reductase 0.0067 0.0165 0.0185
Schistosoma mansoni phosphatidylserine receptor 0.0044 0.0071 0.0072
Trypanosoma cruzi MFS transporter, putative 0.0029 0.0009 0.0025
Brugia malayi Cytochrome P450 family protein 0.0051 0.0099 0.0145
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0329 0.1242 0.3515
Trichomonas vaginalis bromodomain-containing protein, putative 0.0139 0.0462 0.096
Brugia malayi G protein-coupled receptor F59B2.13 0.0047 0.0083 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0019
Echinococcus multilocularis G-protein coupled receptor, putative 0.0047 0.0083 0.0093
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0121 0.0388 0.0806
Leishmania major cathepsin L-like protease 0.0331 0.1254 0.3559
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0172 0.0185
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0023 0.0025
Echinococcus granulosus zinc finger protein 0.0065 0.0157 0.0176
Schistosoma mansoni inositol monophosphatase 0.0041 0.0056 0.0055
Echinococcus multilocularis nuclear receptor nhr 48 0.0181 0.0635 0.0715
Brugia malayi laminin-like protein K08C7.3 precursor 0.0051 0.0096 0.014
Echinococcus multilocularis geminin 0.1951 0.7928 0.892
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0051 0.0096 0.009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0192 0.0216
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0009 0.0009
Loa Loa (eye worm) endoplasmin 0.0042 0.0062 0.0055
Brugia malayi prostaglandin transporter 0.0029 0.0009 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0087 0.0248 0.0427
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0029 0.0009 0.0002
Echinococcus multilocularis sodium bile acid cotransporter 0.053 0.2072 0.2331
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Onchocerca volvulus 0.0036 0.0035 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0134 0.0279
Trypanosoma cruzi aldo/keto reductase, putative 0.0067 0.0165 0.0466
Plasmodium falciparum steroid dehydrogenase, putative 0.0036 0.0035 0.0083
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0135 0.0445 0.1241
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0392 0.1505 0.4167
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 1
Schistosoma mansoni zinc finger protein 0.0065 0.0157 0.0169
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0882 0.3522 0.3963
Onchocerca volvulus 0.0091 0.0261 0.0526
Echinococcus granulosus FTZ F1 alpha 0.0384 0.1472 0.1656
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0121 0.0388 0.0806
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Onchocerca volvulus 0.01 0.0301 0.0608
Brugia malayi laminin alpha chain 0.0051 0.0096 0.014
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.0318 0.0358
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Plasmodium falciparum metacaspase-like protein 0.0029 0.0009 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0047 0.0083 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0536 0.2095 0.2351
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0313 0.0345
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0117 0.037 0.0416
Echinococcus granulosus g protein coupled receptor 0.0047 0.0083 0.0093
Schistosoma mansoni regulator of G protein signaling 0.006 0.0134 0.0143
Onchocerca volvulus 0.0036 0.0035 0.0054
Leishmania major cathepsin L-like protease 0.0087 0.0247 0.07
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Plasmodium vivax vivapain-2 0.0087 0.0247 0.0686
Toxoplasma gondii aminopeptidase n, putative 0.0329 0.1242 0.3515
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0062 0.0146 0.0303
Onchocerca volvulus 0.0058 0.0128 0.0249
Onchocerca volvulus 0.0135 0.0445 0.0908
Loa Loa (eye worm) hypothetical protein 0.0058 0.0125 0.0119
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0117 0.037 0.1049
Schistosoma mansoni elf1 0.0034 0.0027 0.0023
Brugia malayi hypothetical protein 0.0052 0.0103 0.015
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0516 0.2013 0.2008
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Treponema pallidum fructose-bisphosphate aldolase 0.0896 0.358 1
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Mycobacterium tuberculosis Probable dehydrogenase 0.0444 0.1719 0.2987
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0205 0.0733 0.0727
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0111 0.0346 0.0702
Echinococcus granulosus regulator of G protein signaling 7 0.0069 0.0175 0.0196
Plasmodium vivax DNA topoisomerase II, putative 0.0161 0.0552 0.1553
Schistosoma mansoni ankyrin 23/unc44 0.0043 0.0067 0.0068
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0384 0.1472 0.1656
Trichomonas vaginalis DNA topoisomerase II, putative 0.0161 0.0552 0.1148
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0046 0.0079 0.0198
Brugia malayi jmjC domain containing protein 0.0044 0.0071 0.0101
Schistosoma mansoni thyroid hormone receptor 0.0771 0.3063 0.3442
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0084 0.0236 0.0265
Loa Loa (eye worm) hypothetical protein 0.0203 0.0725 0.0719
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0121 0.0388 0.0806
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0062 0.0142 0.0159
Schistosoma mansoni hypothetical protein 0.1951 0.7928 0.8919
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0882 0.3522 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Trypanosoma brucei Heat shock protein 83, putative 0.0042 0.0062 0.0151
Giardia lamblia Heat shock protein HSP 90-alpha 0.0042 0.0062 0.0172
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0074 0.0155
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Leishmania major pteridine reductase 1 0.0036 0.0035 0.0098
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Echinococcus granulosus fatty acid binding protein, adipocyte 0.0067 0.0165 0.0185
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0121 0.0388 0.0429
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0472 0.053
Echinococcus multilocularis allatostatin A receptor 0.0047 0.0083 0.0093
Brugia malayi AKH receptor 0.0047 0.0083 0.0119
Leishmania major cysteine peptidase A (CPA) 0.0087 0.0247 0.07
Schistosoma mansoni hypothetical protein 0.0386 0.148 0.1659
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0049 0.0092 0.0157
Schistosoma mansoni bromodomain containing protein 0.0034 0.0027 0.0023
Echinococcus multilocularis phd:f box containing protein 0.0044 0.0071 0.008
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0069 0.0171 0.0192
Brugia malayi nuclear receptor NHR-88 0.0181 0.0635 0.0985
Trichomonas vaginalis aldo/keto reductase, putative 0.0067 0.0165 0.0343
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0472 0.053
Entamoeba histolytica cysteine proteinase 1, putative 0.0045 0.0073 0.0142
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0148 0.05 0.0555
Onchocerca volvulus 0.0067 0.0165 0.0324
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0067 0.0166 0.0472
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0384 0.1472 0.165
Brugia malayi conserved hypotetical protein 0.0181 0.0635 0.0985
Entamoeba histolytica cysteine proteinase, putative 0.0087 0.0247 0.0631
Onchocerca volvulus 0.0062 0.0146 0.0285
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0386 0.148 0.1665
Echinococcus granulosus mixed lineage leukemia protein mll 0.0042 0.0063 0.0071
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0135 0.0445 0.0438
Mycobacterium leprae putative cytochrome p450 0.0051 0.0099 0.0515
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0236 0.049
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0036 0.0035 0.0098
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0067 0.0166 0.0286
Loa Loa (eye worm) hypothetical protein 0.0107 0.0329 0.0323
Echinococcus granulosus synaptic glycoprotein sc2 0.0046 0.0079 0.0088
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0129 0.035
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0048 0.0086 0.0149
Brugia malayi exodeoxyribonuclease III family protein 0.0117 0.037 0.0569
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0067 0.0166 0.0457
Loa Loa (eye worm) hypothetical protein 0.01 0.0301 0.0294
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0852 0.3396 0.3821
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.0318 0.0312
Trichomonas vaginalis cdc25b, putative 0.0062 0.0146 0.0303
Brugia malayi hypothetical protein 0.0252 0.0926 0.1441
Echinococcus multilocularis cpg binding protein 0.0215 0.0774 0.087
Loa Loa (eye worm) glycogen phosphorylase 0.0114 0.0358 0.0352
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0036 0.0035 0.0098
Loa Loa (eye worm) hypothetical protein 0.0034 0.0027 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0384 0.1472 0.1656
Entamoeba histolytica cysteine proteinase 2 0.0045 0.0073 0.0142
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.01 0.0301 0.0338
Echinococcus multilocularis DNA topoisomerase 1 0.0206 0.0738 0.0829
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0036 0.0035 0.0098
Brugia malayi Regulator of G protein signaling domain containing protein 0.006 0.0134 0.02
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0071 0.0064
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0882 0.3522 0.7328
Brugia malayi oxidoreductase 0.0036 0.0035 0.0044
Entamoeba histolytica short chain dehydrogenase family protein 0.0036 0.0035 0.0035
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0067 0.0165 0.0466
Trichomonas vaginalis glycogen phosphorylase, putative 0.0114 0.0358 0.0746
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0205 0.0733 0.2081
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0046 0.0079 0.0088
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.006 0.0134 0.0151
Brugia malayi Cathepsin L-like precursor 0.0087 0.0247 0.0376
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0583
Onchocerca volvulus 0.0067 0.0165 0.0324
Schistosoma mansoni regulator of G protein signaling 0.006 0.0134 0.0143
Echinococcus granulosus Solute carrier family 22 5 0.2065 0.8396 0.9447
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0064 0.0151 0.0428
Brugia malayi Muscleblind-like protein 0.0149 0.0502 0.0777
Leishmania major hypothetical protein, conserved 0.0031 0.0018 0.005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0065 0.0184
Echinococcus multilocularis carbonyl reductase 1 0.0036 0.0035 0.0039
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0047 0.0083 0.0093
Onchocerca volvulus 0.0047 0.0083 0.0154
Trypanosoma cruzi cysteine proteinase, putative 0.0045 0.0073 0.0206
Loa Loa (eye worm) hypothetical protein 0.0043 0.0064 0.0057
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Mycobacterium ulcerans oxidoreductase 0.0067 0.0165 0.0283
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0035 0.0098
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0121 0.0388 0.1086
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0033 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.0318 0.0902
Loa Loa (eye worm) hypothetical protein 0.0034 0.0027 0.002
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0634
Toxoplasma gondii parasite porphobilinogen synthase PBGS 0.0207 0.074 0.2088
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0033 0.0024 0.0067
Brugia malayi Death domain containing protein 0.0043 0.0067 0.0094
Echinococcus multilocularis nAChR subunit 0.0284 0.1057 0.1189
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0171 0.0592 0.0917
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0536 0.2095 0.2357
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0536 0.2095 0.3273
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Mycobacterium tuberculosis Conserved protein 0.0148 0.05 0.0868
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Onchocerca volvulus 0.0142 0.0473 0.0967
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0109 0.0339 0.0381
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0033 0.0024 0.005
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0111 0.0346 0.0702
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0198
Giardia lamblia Fructose-bisphosphate aldolase 0.0896 0.358 1
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0134 0.0279
Onchocerca volvulus 0.0087 0.0247 0.0496
Schistosoma mansoni nuclear receptor 0.0181 0.0635 0.0708
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.0318 0.0902
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0135 0.0445 0.05
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0036 0.0035 0.0098
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0494 0.1923 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0061 0.0138 0.0155
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0117 0.037 0.0416
Brugia malayi transcription factor E74 isoform 0.0034 0.0027 0.0032
Onchocerca volvulus 0.0536 0.2095 0.4346
Echinococcus granulosus sodium bile acid cotransporter 0.053 0.2072 0.2331
Echinococcus granulosus ETS transcription factor Elf 5 0.0034 0.0027 0.003
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.0083 0.0093
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.005 0.0093 0.0134
Trypanosoma brucei hypothetical protein, conserved 0.0148 0.05 0.1396
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.0318 0.0358
Leishmania major hypothetical protein, conserved 0.0036 0.0035 0.0098
Schistosoma mansoni axis inhibition protein axin 0.006 0.0134 0.0143
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0033 0.0024 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0536 0.2095 0.3273
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0036 0.0035 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0331 0.1254 0.3559
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0023 0.0016
Echinococcus granulosus Solute carrier organic anion transporter family 0.0029 0.0009 0.001
Trichomonas vaginalis mercuric reductase, putative 0.0067 0.0166 0.0346
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0384 0.1472 0.1656
Plasmodium falciparum geranylgeranyltransferase, putative 0.0033 0.0024 0.0052
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0536 0.2095 0.2357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0073 0.0182
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Onchocerca volvulus Cathepsin F homolog 0.0087 0.0247 0.0496
Onchocerca volvulus 0.0536 0.2095 0.4346
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0062 0.0146 0.0303
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0384 0.1472 0.2297
Plasmodium vivax JmjC domain containing protein 0.0066 0.0159 0.0437
Schistosoma mansoni pol-related 0.0067 0.0165 0.0178
Brugia malayi Cathepsin L-like precursor 0.0058 0.0128 0.019
Onchocerca volvulus 0.0062 0.0146 0.0285
Mycobacterium leprae Conserved hypothetical protein 0.0048 0.0085 0.0438
Onchocerca volvulus 0.0062 0.0146 0.0285
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0148 0.05 0.0861
Onchocerca volvulus 0.0165 0.0567 0.1163
Chlamydia trachomatis delta-aminolevulinic acid dehydratase 0.0207 0.074 0.2044
Echinococcus granulosus fatty acid binding protein FABP2 0.0205 0.0732 0.0823
Loa Loa (eye worm) oxidoreductase 0.0067 0.0165 0.0158
Onchocerca volvulus Netrin receptor homolog 0.0043 0.0067 0.0121
Mycobacterium tuberculosis Probable esterase LipL 0.0148 0.05 0.0868
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.0128 0.0267
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0009 0.0003
Leishmania major importin beta-1 subunit, putative 0.0047 0.0083 0.0235
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0045 0.0073 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Schistosoma mansoni opsin-like receptor 0.0047 0.0083 0.0085
Brugia malayi Ets-domain containing protein 0.0232 0.0846 0.1315
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0536 0.2095 0.2089
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0538 0.1525
Echinococcus granulosus nuclear receptor nhr 48 0.0181 0.0635 0.0715
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0051 0.0099 0.0281
Loa Loa (eye worm) hypothetical protein 0.0199 0.0708 0.0702
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0384 0.1472 0.2297
Onchocerca volvulus Cathepsin L homolog 0.0087 0.0247 0.0496
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.024 0.0875 0.0985
Schistosoma mansoni neurotransmitter gated ion channel 0.0252 0.0926 0.1035
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0183 0.0643 0.0724
Echinococcus multilocularis aldo keto reductase 0.0067 0.0165 0.0185
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Schistosoma mansoni tar DNA-binding protein 0.0516 0.2013 0.2259
Echinococcus multilocularis oxidoreductase 0.0036 0.0035 0.0039
Schistosoma mansoni glycogen phosphorylase 0.0114 0.0358 0.0396
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0035 0.0098
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0145 0.0162
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0036 0.0035 0.006
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) dehydrogenase 0.0036 0.0035 0.0028
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0033 0.0024 0.0052
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0057 0.0123 0.0137
Echinococcus multilocularis synaptic glycoprotein sc2 0.0046 0.0079 0.0088
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0035 0.0074
Mycobacterium tuberculosis Conserved protein 0.0148 0.05 0.0868
Entamoeba histolytica heat shock protein 90, putative 0.0042 0.0062 0.0111
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0257
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.0731 0.1136
Brugia malayi Nuclear hormone receptor E75 0.0181 0.0635 0.0985
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Echinococcus granulosus microtubule associated protein 2 0.2184 0.8887 1
Plasmodium falciparum endoplasmin, putative 0.0029 0.0008 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.0494 0.1923 0.3342
Entamoeba histolytica hypothetical protein 0.0047 0.0083 0.0171
Brugia malayi Heterochromatin protein 1 0.007 0.0177 0.0267
Echinococcus granulosus netrin receptor unc 5 0.0043 0.0067 0.0075
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0035 0.0039
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0051 0.0099 0.0171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0384 0.1472 0.1656
Plasmodium falciparum thioredoxin reductase 0.0067 0.0166 0.0457
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0083
Echinococcus granulosus caspase 2 0.0029 0.0009 0.001
Leishmania major hypothetical protein, conserved 0.0148 0.05 0.1417
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Brugia malayi Common central domain of tyrosinase family protein 0.0091 0.0261 0.0399
Schistosoma mansoni hypothetical protein 0.0065 0.0155 0.0167
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0035 0.0074
Onchocerca volvulus 0.0031 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Plasmodium vivax polyprenol reductase, putative 0.0046 0.0079 0.0207
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0392 0.1505 0.3131
Loa Loa (eye worm) oxidoreductase 0.0067 0.0165 0.0158
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0047 0.0083 0.0085
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0047 0.0083 0.0093
Brugia malayi Immunoglobulin I-set domain containing protein 0.0043 0.0067 0.0094
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0181 0.0635 0.0629
Giardia lamblia Short-chain dehydrogenase, putative 0.0036 0.0035 0.0096
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0155 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.003 0.001 0.0021
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Loa Loa (eye worm) jmjC domain-containing protein 0.0172 0.0597 0.059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0384 0.1472 0.1466
Onchocerca volvulus 0.0087 0.0247 0.0496
Mycobacterium ulcerans ketoacyl reductase 0.0036 0.0035 0.006
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0083 0.0085
Onchocerca volvulus 0.0148 0.05 0.1022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0057 0.0123 0.0212
Schistosoma mansoni jumonji/arid domain-containing protein 0.013 0.0423 0.0469
Leishmania major DNA polymerase eta, putative 0.0057 0.0123 0.0347
Schistosoma mansoni hypothetical protein 0.0041 0.0057 0.0057
Schistosoma mansoni nAChR subunit 0.0252 0.0926 0.1035
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi Intermediate filament tail domain containing protein 0.0142 0.0473 0.0731
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0086 0.0229
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0036 0.0035 0.0035
Echinococcus granulosus neuropeptide receptor 0.0047 0.0083 0.0093
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0081 0.023
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0084 0.0236 0.0358
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0047 0.0083 0.0093
Leishmania major DNA topoisomerase IB, large subunit 0.0206 0.0738 0.2093
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0036 0.0035 0.006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0384 0.1472 0.1466
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0065 0.016
Onchocerca volvulus 0.0252 0.0926 0.1911
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0062 0.0142 0.0152
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0039 0.0199
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0067 0.0166 0.0286
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0438 0.1692 0.2916
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Loa Loa (eye worm) RGS-3 protein 0.006 0.0134 0.0127
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Plasmodium falciparum glutathione reductase 0.0195 0.0691 0.1948
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0384 0.1472 0.1466
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0103 0.0276
Plasmodium vivax vivapain-1 0.0045 0.0073 0.0192
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0384 0.1472 0.165
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0153 0.052 0.0578
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0134 0.0279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0087 0.0247 0.0514
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0236 0.0645
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.0083 0.0085
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0023 0.0025
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.006 0.0136 0.0318
Entamoeba histolytica hypothetical protein 0.0048 0.0086 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0384 0.1472 0.2297
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0051 0.0099 0.0172
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0121 0.0388 0.0436
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0303 0.1136 0.3223
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Brugia malayi MH2 domain containing protein 0.0379 0.1448 0.226
Trichomonas vaginalis D-aminoacylase, putative 0.0148 0.05 0.1039
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Brugia malayi hypothetical protein 0.0252 0.0926 0.1441
Toxoplasma gondii oxidoreductase, putative 0.0036 0.0035 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Brugia malayi hypothetical protein 0.006 0.0134 0.02
Schistosoma mansoni porphobilinogen synthase 0.0207 0.074 0.0825
Onchocerca volvulus Glycogen phosphorylase homolog 0.0114 0.0358 0.0728
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0067 0.0166 0.025
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0029 0.0008 0.0009
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0252 0.0926 0.1042
Echinococcus granulosus cathepsin L 0.0045 0.0073 0.0082
Onchocerca volvulus 0.0062 0.0142 0.0277
Trichomonas vaginalis set domain proteins, putative 0.1194 0.4807 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Schistosoma mansoni tyrosinase precursor 0.0091 0.0261 0.0287
Brugia malayi beta-lactamase family protein 0.0148 0.05 0.0772
Trypanosoma cruzi trypanothione reductase, putative 0.0195 0.0691 0.196
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0121 0.0388 0.1086
Brugia malayi jmjC domain containing protein 0.0172 0.0597 0.0925
Trypanosoma cruzi heat shock protein 90, putative 0.0028 0.0004 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0036 0.0035 0.0467
Trypanosoma cruzi cysteine peptidase, putative 0.0331 0.1254 0.3559
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0036 0.0035 0.0054
Schistosoma mansoni hypothetical protein 0.0623 0.2453 0.2755
Echinococcus granulosus sex peptide receptor 0.0047 0.0083 0.0093
Echinococcus granulosus DNA topoisomerase 1 0.0206 0.0738 0.0829
Plasmodium vivax steroid dehydrogenase, putative 0.0036 0.0035 0.0083
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0029 0.0008 0.0002
Loa Loa (eye worm) hypothetical protein 0.0145 0.0487 0.048
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0033 0.0036
Echinococcus granulosus nAChR subunit 0.0536 0.2095 0.2357
Schistosoma mansoni ap endonuclease 0.0117 0.037 0.0409
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0035 0.0098
Plasmodium falciparum porphobilinogen synthase 0.0207 0.074 0.2088
Echinococcus granulosus cathepsin l1 0.0058 0.0128 0.0144
Trypanosoma brucei unspecified product 0.0078 0.021 0.0571
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0033 0.0024 0.0019
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0392 0.1505 0.3131
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0036 0.0035 0.0073
Echinococcus multilocularis JmjC domain containing protein 4 0.0044 0.0071 0.008
Loa Loa (eye worm) hypothetical protein 0.0069 0.0172 0.0165
Entamoeba histolytica phosphofructokinase, putative 0.0223 0.0805 0.22
Echinococcus granulosus intermediate filament protein 0.0142 0.0473 0.0532
Echinococcus multilocularis cathepsin L cysteine protease 0.0087 0.0247 0.0277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Mycobacterium tuberculosis Probable oxidoreductase 0.1424 0.5754 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Echinococcus granulosus thyroid hormone receptor alpha 0.0181 0.0635 0.0715
Loa Loa (eye worm) hypothetical protein 0.0062 0.0146 0.0139
Onchocerca volvulus 0.0055 0.0113 0.0217
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0384 0.1472 0.1656
Echinococcus granulosus cysteine protease 0.0045 0.0073 0.0082
Schistosoma mansoni ets-related 0.0034 0.0027 0.0023
Brugia malayi regulator of G-protein signaling rgs-7 0.006 0.0134 0.02
Echinococcus granulosus carbonyl reductase 1 0.0036 0.0035 0.0039
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.0083 0.0093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0045 0.0073 0.0182
Loa Loa (eye worm) hypothetical protein 0.007 0.0175 0.0168
Echinococcus granulosus g protein coupled receptor 0.0047 0.0083 0.0093
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0181 0.0635 0.0715
Brugia malayi CHE-14 protein 0.0043 0.0064 0.0089
Onchocerca volvulus 0.0036 0.0035 0.0054
Brugia malayi jmjC domain containing protein 0.0059 0.0132 0.0196
Loa Loa (eye worm) hypothetical protein 0.006 0.0134 0.0127
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Loa Loa (eye worm) acetyltransferase 0.0461 0.1789 0.1784
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0138 0.0148
Loa Loa (eye worm) hypothetical protein 0.0066 0.016 0.0153
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0199 0.0708 0.1457
Brugia malayi carbohydrate phosphorylase 0.0114 0.0358 0.0551
Brugia malayi Dehydrogenases, short chain protein 30 0.0036 0.0035 0.0044
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0121 0.0388 0.0806
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0112 0.0193
Echinococcus multilocularis neuropeptide receptor A26 0.053 0.2073 0.2332
Brugia malayi nuclear receptor RXR 0.0203 0.0725 0.1126
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0205 0.0733 0.0818
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Brugia malayi neuropeptide F receptor 0.0047 0.0083 0.0119
Schistosoma mansoni hypothetical protein 0.0267 0.0988 0.1105
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0079 0.0198
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0081 0.023
Toxoplasma gondii NADPH-glutathione reductase 0.0067 0.0166 0.0457
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0444 0.1719 0.2987
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0538 0.1525
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0035 0.0098
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0047 0.0083 0.0119
Schistosoma mansoni steroid dehydrogenase 0.0036 0.0035 0.0032
Echinococcus granulosus chromobox protein 1 0.007 0.0177 0.0199
Echinococcus granulosus ewsr:fli fusion protein type 0.0034 0.0027 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0236 0.049
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0284 0.1058 0.3002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0087 0.0247 0.0514
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0036 0.0035 0.006
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0071 0.0201
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0056 0.0096
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0048 0.0086 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0384 0.1472 0.2297
Echinococcus multilocularis thioredoxin glutathione reductase 0.0195 0.0691 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0009 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0151 0.0405
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Trypanosoma brucei hypothetical protein, conserved 0.0135 0.0445 0.1241
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 0.3959
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0121 0.0388 0.1026
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0148 0.05 0.0493
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0386 0.148 0.1659
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.006 0.0136 0.0319
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0536 0.2095 0.3273
Echinococcus multilocularis tumor protein p63 0.0373 0.1423 0.1601
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0065 0.0169
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0035 0.006
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0252 0.0926 0.1041
Loa Loa (eye worm) leucine Rich Repeat family protein 0.004 0.0054 0.0047
Echinococcus granulosus JmjC domain containing protein 4 0.0044 0.0071 0.008
Schistosoma mansoni nuclear hormone receptor 0.0181 0.0635 0.0708
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0051 0.0099 0.0171
Schistosoma mansoni hypothetical protein 0.0047 0.0083 0.0085
Echinococcus multilocularis aldehyde reductase 0.0048 0.0085 0.0095
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Schistosoma mansoni z-protein (S1r protein) 0.0069 0.0175 0.0189
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0083
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0051 0.0099 0.0171
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0072
Plasmodium vivax delta-aminolevulinic acid dehydratase, putative 0.0207 0.074 0.2088
Trichomonas vaginalis endoplasmin, putative 0.0029 0.0008 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0384 0.1472 0.1466
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.007
Echinococcus multilocularis regulator of G protein signaling 3 0.006 0.0134 0.0151
Plasmodium vivax unspecified product 0.0045 0.0073 0.0192
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Schistosoma mansoni amine GPCR 0.0047 0.0083 0.0085
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0047 0.0083 0.0119
Loa Loa (eye worm) bromodomain containing protein 0.0047 0.0084 0.0077
Schistosoma mansoni biogenic amine receptor 0.0047 0.0083 0.0085
Brugia malayi hypothetical protein 0.0047 0.0083 0.0119
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0536 0.2095 0.2357
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0084 0.0236 0.0257
Schistosoma mansoni hypothetical protein 0.1951 0.7928 0.8919
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0882 0.3522 1
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0036 0.0035 0.0098
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0046 0.0079 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0384 0.1472 0.1466
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0036 0.0035 0.006
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0036 0.0035 0.0098
Plasmodium vivax endoplasmin, putative 0.0042 0.0062 0.016
Onchocerca volvulus 0.0536 0.2095 0.4346
Schistosoma mansoni cpg binding protein 0.0215 0.0774 0.0863
Schistosoma mansoni sodium-bile acid cotransporter related 0.053 0.2072 0.2325
Onchocerca volvulus 0.0047 0.0083 0.0154
Loa Loa (eye worm) hypothetical protein 0.0033 0.0022 0.0016
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0183 0.0643 0.0724
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0051 0.0099 0.0171
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Plasmodium vivax importin-beta 2, putative 0.0058 0.0129 0.035
Schistosoma mansoni netrin receptor unc5 0.0043 0.0067 0.0068
Leishmania major cytochrome p450-like protein 0.0051 0.0099 0.0281
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0121 0.0388 0.0381
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Schistosoma mansoni alpha-1 adrenergic receptor 0.0047 0.0083 0.0085
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0072
Echinococcus multilocularis expressed conserved protein 0.0093 0.0272 0.0305
Onchocerca volvulus 0.0067 0.0165 0.0324
Schistosoma mansoni sodium-bile acid cotransporter related 0.0267 0.0989 0.1105
Trypanosoma brucei heat shock protein, putative 0.0042 0.0062 0.0151
Entamoeba histolytica hypothetical protein, conserved 0.0036 0.0035 0.0035
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0181 0.0635 0.1305
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0536 0.2095 0.2089
Echinococcus multilocularis sodium bile acid cotransporter 0.053 0.2072 0.2331
Entamoeba histolytica phosphofructokinase, putative 0.0223 0.0805 0.22
Schistosoma mansoni neuropeptide receptor 0.0047 0.0083 0.0085
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0896 0.358 1
Mycobacterium ulcerans dehydrogenase/reductase 0.0036 0.0035 0.006
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0229 0.0638
Echinococcus granulosus retinol dehydrogenase 11 0.0036 0.0035 0.0039
Brugia malayi 6-phosphofructokinase 0.0223 0.0805 0.1252
Schistosoma mansoni heat shock protein 0.0042 0.0062 0.0062
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.018 0.063 0.1787
Brugia malayi Nuclear hormone receptor-like 1 0.0203 0.0725 0.1126
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0083 0.0173
Echinococcus multilocularis g protein coupled receptor 0.0047 0.0083 0.0093
Plasmodium vivax thioredoxin reductase, putative 0.0195 0.0691 0.1948
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0074 0.0155
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.01 0.0301 0.0338
Mycobacterium tuberculosis Probable lipase LipD 0.0148 0.05 0.0868
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0333 0.126 0.3577
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0248 0.0703
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0384 0.1472 0.2297
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0036 0.0035 0.0044
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0494 0.1923 0.3342
Schistosoma mansoni microtubule-associated protein tau 0.2184 0.8887 1
Brugia malayi hypothetical protein 0.0252 0.0926 0.1441
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0096
Loa Loa (eye worm) heat shock protein 90 0.0042 0.0062 0.0055
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0056 0.0117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0181 0.0635 0.0629
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0035 0.0074
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.0083 0.0085
Trypanosoma brucei short-chain dehydrogenase, putative 0.0036 0.0035 0.0074
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0036 0.0035 0.0073
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0052 0.0101 0.0113
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0117 0.037 0.1049
Echinococcus multilocularis chromobox protein 1 0.007 0.0177 0.0199
Trichomonas vaginalis O-linked N-acetylglucosamine transferase, ogt, putative 0.0033 0.0022 0.0047
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0067 0.0166 0.2246
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0036 0.0035 0.018
Trichomonas vaginalis chromobox protein, putative 0.007 0.0177 0.0369
Trypanosoma cruzi cysteine protease, putative 0.0045 0.0073 0.0206
Loa Loa (eye worm) hypothetical protein 0.0203 0.0725 0.0719
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Loa Loa (eye worm) hypothetical protein 0.0044 0.0071 0.0064
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0036 0.0035 0.0074
Trichomonas vaginalis cdc25c, putative 0.0062 0.0146 0.0303
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0023 0.0025
Schistosoma mansoni hypothetical protein 0.0047 0.0083 0.0085
Echinococcus granulosus alpha 1A adrenergic receptor 0.0047 0.0083 0.0093
Mycobacterium ulcerans DNA polymerase IV 0.0085 0.0238 0.041
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0069 0.0172 0.0185
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0036 0.0035 0.0096
Schistosoma mansoni tyrosinase precursor 0.0091 0.0261 0.0287
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Onchocerca volvulus 0.0046 0.0079 0.0145
Loa Loa (eye worm) hypothetical protein 0.1577 0.6385 0.6383
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0067 0.0166 0.0457
Mycobacterium ulcerans oxidoreductase 0.0036 0.0035 0.006
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0087 0.0247 0.0277
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.024 0.0875 0.0985
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Plasmodium vivax vivapain-3 0.0045 0.0073 0.0192
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.005 0.0093 0.0134
Brugia malayi Papain family cysteine protease containing protein 0.0045 0.0073 0.0104
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0074 0.0155
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0047 0.0083 0.0119
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0051 0.0099 0.0172
Schistosoma mansoni hypothetical protein 0.0049 0.0088 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.0083 0.0085
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0057
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0044 0.0068 0.0069
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0384 0.1472 0.1656
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0536 0.2095 0.2357
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0043 0.0067 0.0075
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0009 0.0009
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.0206 0.0738 0.2093
Loa Loa (eye worm) D-ets-2 protein 0.0034 0.0027 0.002
Plasmodium vivax unspecified product 0.0029 0.0007 0.0003
Echinococcus multilocularis aldo keto reductase 0.0067 0.0165 0.0185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.0083 0.0085
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0536 0.2095 0.3273
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.0083 0.0093
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0306 0.1149 0.1996
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0139 0.0462 0.1296
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0092 0.0194
Leishmania major hypothetical protein, conserved 0.0052 0.0103 0.029
Mycobacterium tuberculosis Probable hydrolase 0.0148 0.05 0.0868
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0155 0.0174
Brugia malayi photoreceptor-specific nuclear receptor 0.0384 0.1472 0.2297
Mycobacterium tuberculosis Probable oxidoreductase 0.0036 0.0035 0.006
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0392 0.1505 0.3131
Loa Loa (eye worm) hypothetical protein 0.0091 0.0261 0.0255
Brugia malayi jmjC domain containing protein 0.0044 0.0071 0.0101
Schistosoma mansoni jun-related protein 0.0287 0.1069 0.1196
Echinococcus multilocularis ETS transcription factor Elf 1 0.0034 0.0027 0.003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0384 0.1472 0.165
Loa Loa (eye worm) hypothetical protein 0.0039 0.005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0029 0.0009 0.0009
Trichomonas vaginalis heat shock protein, putative 0.0029 0.0008 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0297 0.0333
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0003 0.0006
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0252 0.0926 0.092
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0205 0.0733 0.0825
Entamoeba histolytica phosphofructokinase, putative 0.0223 0.0805 0.22
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0083 0.0093
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.0002
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0135 0.0445 0.1262
Echinococcus granulosus hypothetical protein 0.0067 0.0165 0.0185
Loa Loa (eye worm) intermediate filament protein 0.0142 0.0473 0.0467
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0051 0.0099 0.0171
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.0083 0.0093
Brugia malayi chromobox protein homolog 3 0.0039 0.005 0.0068
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0086 0.0229
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0047 0.0083 0.0085
Onchocerca volvulus 0.0536 0.2095 0.4346
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0062 0.0146 0.0156
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0384 0.1472 0.165
Toxoplasma gondii cytochrome p450 superfamily protein 0.0051 0.0099 0.0266
Schistosoma mansoni carbonyl reductase 0.0036 0.0035 0.0032
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Brugia malayi ecdysone receptor 0.0181 0.0635 0.0985
Echinococcus granulosus cytochrome P450 2K1 0.0051 0.0099 0.0111
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0165 0.0247
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0318 0.0662
Brugia malayi Ets-domain containing protein 0.0034 0.0027 0.0032
Leishmania major cathepsin L-like protease 0.0087 0.0247 0.07
Plasmodium vivax heat shock protein 86, putative 0.0042 0.0062 0.016
Loa Loa (eye worm) CYP4Cod1 0.0087 0.0248 0.0241
Entamoeba histolytica hypothetical protein 0.0297 0.1113 0.3064
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0138 0.0148
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0086 0.0244
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0036 0.0035 0.0098
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Echinococcus multilocularis GPCR, family 2 0.0065 0.0155 0.0174
Schistosoma mansoni slit 0.0051 0.0097 0.0101
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0067 0.0166 0.0448
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0042 0.0063 0.0071
Loa Loa (eye worm) RNA binding protein 0.0516 0.2013 0.2008
Echinococcus multilocularis glycine receptor subunit beta 0.0536 0.2095 0.2357
Echinococcus multilocularis delta aminolevulinic acid dehydratase 0.0207 0.074 0.0832
Loa Loa (eye worm) oxidoreductase 0.0067 0.0165 0.0158
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Leishmania major GTP-binding protein, putative 0.0043 0.0065 0.0184
Echinococcus multilocularis regulator of G protein signaling 7 0.0069 0.0175 0.0196
Entamoeba histolytica short chain dehydrogenase family protein 0.0036 0.0035 0.0035
Echinococcus granulosus glycogen phosphorylase 0.0114 0.0358 0.0403
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Trichomonas vaginalis ap endonuclease, putative 0.0117 0.037 0.0769
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0079 0.0163
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0033 0.0036
Leishmania major mitochondrial DNA polymerase beta 0.0333 0.126 0.3577
Entamoeba histolytica hypothetical protein 0.0297 0.1113 0.3064
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0029 0.0009 0.0019
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0036 0.0035 0.0074
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0386 0.148 0.231
Loa Loa (eye worm) hypothetical protein 0.0284 0.1057 0.1051
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.006 0.0136 0.0379
Echinococcus granulosus peptide allatostatin:somatostatin 0.0047 0.0083 0.0093
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Plasmodium falciparum metacaspase 1 0.0029 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0149 0.0502 0.0496
Entamoeba histolytica cysteine proteinase, putative 0.0087 0.0247 0.0631
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Brugia malayi hypothetical protein 0.0036 0.0035 0.0044
Trichomonas vaginalis steroid dehydrogenase, putative 0.0036 0.0035 0.0073
Echinococcus granulosus jun protein 0.0353 0.1342 0.1509
Echinococcus granulosus transcription factor Dp 1 0.0119 0.0377 0.0424
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Trypanosoma cruzi cruzipain precursor, putative 0.0331 0.1254 0.3559
Brugia malayi DNA-binding protein D-ETS-3 0.0034 0.0027 0.0032
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0067 0.0165 0.0185
Brugia malayi sodium-independent organic anion transporter family protein 0.0029 0.0009 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0047 0.0083 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0536 0.2095 0.2357
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0135 0.0445 0.1249
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0192 0.0679 0.0757
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0036 0.0035 0.0098
Onchocerca volvulus 0.0036 0.0035 0.0054
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0333 0.126 0.3577
Entamoeba histolytica rodhanase-like domain containing protein 0.0062 0.0146 0.0346
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0023 0.0049
Echinococcus multilocularis g-protein coupled receptor 0.0047 0.0083 0.0093
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0036 0.0035 0.0039
Onchocerca volvulus 0.0181 0.0635 0.1305
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0161 0.0552 0.0854
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0117 0.037 0.1032
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Brugia malayi Dopamine receptor protein 2 0.0047 0.0083 0.0119
Toxoplasma gondii DNA topoisomerase I, putative 0.0206 0.0738 0.2081
Brugia malayi Papain family cysteine protease containing protein 0.0045 0.0073 0.0104
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0047 0.0083 0.0076
Leishmania major short chain dehydrogenase, putative 0.0036 0.0035 0.0098
Leishmania major trypanothione reductase 0.0195 0.0691 0.196
Onchocerca volvulus 0.0536 0.2095 0.4346
Trichomonas vaginalis phosphofructokinase, putative 0.0223 0.0805 0.1675
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Echinococcus granulosus 6 phosphofructokinase 0.0223 0.0805 0.0906
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0024 0.0067
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Leishmania major cathepsin L-like protease 0.0331 0.1254 0.3559
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0103 0.0276
Trichomonas vaginalis phosphofructokinase, putative 0.006 0.0136 0.0283
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0047 0.0083 0.0085
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0051 0.0099 0.0281
Trypanosoma cruzi DNA polymerase kappa, putative 0.0085 0.0238 0.0676
Echinococcus multilocularis Regulator of G protein signaling 20 0.006 0.0134 0.0151
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0046 0.0079 0.0222
Onchocerca volvulus 0.0087 0.0247 0.0496
Echinococcus granulosus somatostatin receptor 0.0047 0.0083 0.0093
Loa Loa (eye worm) follicle stimulating hormone receptor 0.075 0.2977 0.2972
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Onchocerca volvulus 0.0047 0.0083 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0051 0.0099 0.0172
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0062 0.0146 0.0163
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0112 0.0125
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0161 0.0552 0.0854
Loa Loa (eye worm) hypothetical protein 0.0062 0.0146 0.0139
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0205 0.0733 0.2081
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Trichomonas vaginalis ran, putative 0.0043 0.0065 0.0136
Loa Loa (eye worm) glutathione reductase 0.0195 0.0691 0.0684
Loa Loa (eye worm) hypothetical protein 0.0036 0.0035 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0045 0.0073 0.0152
Entamoeba histolytica hypothetical protein 0.0297 0.1113 0.3064
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0046 0.0079 0.0207
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0103 0.0313 0.0345
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.0083 0.0093
Echinococcus multilocularis lysine specific demethylase 6a 0.0077 0.0205 0.0231
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0896 0.358 0.7449
Plasmodium vivax geranylgeranyltransferase, putative 0.0033 0.0024 0.0052
Trichomonas vaginalis aldo-keto reductase, putative 0.0067 0.0165 0.0343
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0083
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0096
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0065 0.0073
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.0206 0.0738 0.2074
Leishmania major heat shock protein 83-1 0.0042 0.0062 0.0175
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.0083 0.0085
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0049 0.0092 0.0159
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0051 0.0096 0.014
Echinococcus multilocularis 0.0051 0.0099 0.0111
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0067 0.0166 0.0472
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0046 0.0079 0.0207
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0177 0.017
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0036 0.0035 0.0039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0331 0.1254 0.3544
Schistosoma mansoni cathepsin F (C01 family) 0.0058 0.0128 0.0137
Schistosoma mansoni nAChR subunit 0.0536 0.2095 0.2351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.0083 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0079 0.0198
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0181 0.0635 0.0715
Loa Loa (eye worm) hypothetical protein 0.0113 0.0352 0.0345
Brugia malayi beta-lactamase family protein 0.0148 0.05 0.0772
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0033 0.0024 0.0052
Entamoeba histolytica cysteine protease, putative 0.0045 0.0073 0.0142
Loa Loa (eye worm) oxidoreductase 0.0067 0.0165 0.0158
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0033 0.0024 0.0019
Schistosoma mansoni short chain dehydrogenase 0.0036 0.0035 0.0032
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0223 0.0805 0.4187
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0223 0.0805 0.2249
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0536 0.2095 0.2357
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0046 0.0079 0.0222
Brugia malayi Nuclear hormone receptor-like 1 0.0384 0.1472 0.2297
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.0318 0.0358
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0869 0.0977
Brugia malayi Nuclear hormone receptor E75 0.0181 0.0635 0.0985
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0136 0.0371
Loa Loa (eye worm) oxidoreductase 0.0036 0.0035 0.0028
Onchocerca volvulus 0.0036 0.0035 0.0054
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Schistosoma mansoni hypothetical protein 0.0065 0.0155 0.0167
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0033 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.005 0.0105
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0056 0.0158
Echinococcus granulosus fatty acid binding protein FABP2 0.0067 0.0165 0.0185
Toxoplasma gondii PLU-1 family protein 0.0042 0.0062 0.016
Schistosoma mansoni steroid hormone receptor ad4bp 0.0384 0.1472 0.165
Onchocerca volvulus 0.0036 0.0035 0.0054
Trichomonas vaginalis esterase, putative 0.0148 0.05 0.1039
Leishmania major quinonoid dihydropteridine reductase 0.0036 0.0035 0.0098
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0077 0.0205 0.0223
Giardia lamblia Rab geranylgeranyltransferase 0.0392 0.1505 0.4203
Loa Loa (eye worm) hypothetical protein 0.0252 0.0926 0.092
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0145 0.0484 0.0544
Trypanosoma cruzi hypothetical protein, conserved 0.0148 0.05 0.1417
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0076
Trypanosoma cruzi metacaspase 5, putative 0.0029 0.0009 0.0024
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0033 0.0024 0.005
Loa Loa (eye worm) hypothetical protein 0.0148 0.05 0.0493
Loa Loa (eye worm) hypothetical protein 0.0343 0.1302 0.1296
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0067 0.0165 0.0185
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0183 0.0643 0.1826
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0257 0.0948 0.1973
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0034 0.0027 0.002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.006 0.0134 0.0143
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0084 0.0236 0.0257
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0036 0.0035 0.0074
Brugia malayi hypothetical protein 0.0029 0.0009 0.0003
Echinococcus granulosus neuropeptide receptor A26 0.053 0.2073 0.2332
Onchocerca volvulus Bile acid receptor homolog 0.0688 0.2723 0.5655
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0029 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Brugia malayi Ets-domain containing protein 0.0232 0.0846 0.1315
Loa Loa (eye worm) hypothetical protein 0.0244 0.0895 0.0888
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.001 0.0021
Onchocerca volvulus 0.0062 0.0146 0.0285
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0036 0.0035 0.0083
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0067 0.0166 0.0448
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0051 0.0099 0.0172
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0329 0.1242 0.3515
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0067 0.0166 0.0472
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0067 0.0165 0.0247
Brugia malayi Thioredoxin reductase 0.0195 0.0691 0.1072
Echinococcus granulosus neurogenic locus notch protein 0.0051 0.0096 0.0108
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0044
Schistosoma mansoni DNA topoisomerase type I 0.0206 0.0738 0.0823
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0036 0.0035 0.006
Echinococcus granulosus beta LACTamase domain containing family member 0.0148 0.05 0.0562
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0035 0.0083
Entamoeba histolytica hypothetical protein 0.006 0.0134 0.0314
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.024 0.0875 0.0978
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0047 0.0083 0.0093
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0033 0.0024 0.0042
Trypanosoma cruzi DNA topoisomerase II, putative 0.0153 0.0518 0.1469
Loa Loa (eye worm) hypothetical protein 0.0238 0.0869 0.0862
Echinococcus granulosus steroid dehydrogenase 0.0036 0.0035 0.0039
Trypanosoma brucei DNA polymerase eta, putative 0.0057 0.0123 0.0323
Schistosoma mansoni porphobilinogen synthase 0.0207 0.074 0.0825
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006
Brugia malayi bZIP transcription factor family protein 0.0353 0.1342 0.2092
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0023 0.0018
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0036 0.0035 0.0035
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.01 0.0301 0.0331
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0036 0.0035 0.006
Echinococcus multilocularis retinol dehydrogenase 11 0.0036 0.0035 0.0039
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0023 0.0039
Loa Loa (eye worm) fibroinase 0.0087 0.0247 0.024
Echinococcus multilocularis lamin dm0 0.0142 0.0473 0.0532
Loa Loa (eye worm) hypothetical protein 0.0046 0.0079 0.0072
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0036 0.0035 0.0054
Plasmodium vivax 6-phosphofructokinase, putative 0.006 0.0136 0.0371
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.006 0.0136 0.0371
Entamoeba histolytica glycogen phosphorylase, putative 0.0049 0.0092 0.0194
Echinococcus multilocularis netrin receptor unc 5 0.0043 0.0067 0.0075
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0095 0.0278 0.0482
Echinococcus granulosus expressed protein 0.1162 0.4675 0.526
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.0238 0.0653
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.015 0.0506 0.0569
Loa Loa (eye worm) hypothetical protein 0.0536 0.2095 0.2089
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0036 0.0035 0.006
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0057 0.0123 0.0137
Loa Loa (eye worm) hypothetical protein 0.0384 0.1472 0.1466
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0036 0.0035 0.0098
Echinococcus granulosus axis inhibition protein axin 0.006 0.0134 0.0151
Mycobacterium ulcerans short chain dehydrogenase 0.0036 0.0035 0.006

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 500 nM Binding affinity against Diazepam sensitive (DS) Gamma-aminobutyric-acid A receptor ChEMBL. 7752192
IC50 (binding) > 500 nM Binding affinity against Diazepam sensitive (DS) Gamma-aminobutyric-acid A receptor ChEMBL. 7752192
Ki (binding) = 28.5 nM Binding affinity for Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 ChEMBL. 9767648
Ki (binding) = 28.5 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha5-beta3-gamma2 ChEMBL. 10633039
Ki (binding) = 28.5 nM Binding affinity for Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 ChEMBL. 9767648
Ki (binding) = 28.5 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha5-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity against alpha1-beta3-gamma2 GABAA/BzR receptor subtype. ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity of the compound tested against alpha2-beta3-gamma2 GABAA/BzR receptor subtype. ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity against alpha3-beta3-gamma2 GABAA/BzR receptor subtype. ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity against Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2 ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha1-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha2-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha3-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha6-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity against alpha1-beta3-gamma2 GABAA/BzR receptor subtype. ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity of the compound tested against alpha2-beta3-gamma2 GABAA/BzR receptor subtype. ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity against alpha3-beta3-gamma2 GABAA/BzR receptor subtype. ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity against Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2 ChEMBL. 9767648
Ki (binding) > 300 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha1-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha2-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha3-beta3-gamma2 ChEMBL. 10633039
Ki (binding) > 300 nM Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha6-beta3-gamma2 ChEMBL. 10633039
Ki (binding) = 540 nM Binding affinity against Diazepam insensitive (DI) Gamma-aminobutyric-acid A receptor ChEMBL. 7752192
Ki (binding) = 540 nM Binding affinity against Diazepam insensitive (DI) Gamma-aminobutyric-acid A receptor ChEMBL. 7752192
Ki (binding) > 1000 nM Binding affinity against Diazepam insensitive (DI) Gamma-aminobutyric-acid A receptor ChEMBL. 7752192
Ki (binding) > 1000 nM Binding affinity against Diazepam insensitive (DI) Gamma-aminobutyric-acid A receptor ChEMBL. 7752192
Ratio (binding) > 10.5 It is the ratio of Ki value for alpha1-beta3-gamma2 to that of alpha5-beta3-gamma2 ChEMBL. 9767648
Ratio (binding) > 10.5 Selectivity ratio of alpha1 beta3 gamma2 GABA A / BzR and alpha5 beta3 gamma2 GABA A / BzR ChEMBL. 10633039

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

3 literature references were collected for this gene.

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