Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.2853 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.2853 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 1 | 1 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0034 | 1 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.2853 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.2853 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.2853 | 0.2853 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0034 | 1 | 1 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 1 | 0.5 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0034 | 1 | 1 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.2853 | 0.5 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.2853 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.2853 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.2853 | 0.2853 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 1 | 0.5 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.2853 | 0.2853 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.2853 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.2853 | 0.5 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.2853 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.2853 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.2853 | 0.2853 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.