Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.1296 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1296 | 0.42 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0292 | 0.1004 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1296 | 0.4153 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0018 | 0.0795 | 0.2337 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0292 | 0.1004 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0129 | 0.7884 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0753 | 0.2587 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0292 | 0.0292 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.1752 | 0.1752 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1878 | 0.1878 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0497 | 0.161 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0795 | 0.5627 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0292 | 0.0292 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0753 | 0.2587 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0281 | 0.0966 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0292 | 0.1004 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.082 | 0.0944 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.0276 | 0.0949 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0149 | 0.0085 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0292 | 0.0958 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0276 | 0.0459 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0276 | 0.2332 |
Onchocerca volvulus | 0.001 | 0.0276 | 0.085 | |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Leishmania major | trypanothione reductase | 0.0051 | 0.2911 | 1 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0008 | 0.0149 | 0.0085 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0018 | 0.0795 | 0.2337 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0149 | 0.0484 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0008 | 0.0149 | 0.0484 |
Schistosoma mansoni | DNA ligase IV | 0.001 | 0.0276 | 0.0276 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0281 | 0.0966 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0008 | 0.0149 | 0.0085 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0795 | 0.2337 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0149 | 0.0484 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.1296 | 0.1483 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.1296 | 0.6636 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.164 | 0.5312 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.001 | 0.0276 | 0.039 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.082 | 0.0944 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.2911 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0292 | 0.0958 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.3087 | 1 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0292 | 0.0292 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0292 | 0.0292 |
Echinococcus granulosus | expressed protein | 0.0009 | 0.0253 | 0.087 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0753 | 0.2439 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0795 | 0.2337 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0795 | 0.2731 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0795 | 0.2575 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.001 | 0.0276 | 0.0459 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.1296 | 0.6636 |
Brugia malayi | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.164 | 0.164 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.001 | 0.0276 | 0.0733 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0292 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.2007 | 0.2007 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.001 | 0.0276 | 0.0459 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0753 | 0.2439 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0292 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0753 | 0.0753 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0008 | 0.0149 | 0.0085 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0008 | 0.0149 | 0.0484 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.2911 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0149 | 0.0484 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0292 | 0.1004 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0253 | 0.0253 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0292 | 0.0958 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.0276 | 0.039 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0292 | 0.1004 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0018 | 0.0795 | 0.2337 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.1296 | 0.1483 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0795 | 0.5627 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.0276 | 0.0276 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0274 | 0.0886 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0292 | 0.0947 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.2911 | 0.8498 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0753 | 0.2587 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0149 | 0.0085 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0.0149 | 0.0484 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0795 | 0.2731 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.1878 | 0.645 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.2911 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0292 | 0.1004 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0753 | 0.0753 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0276 | 0.2332 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.001 | 0.0276 | 0.0421 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.1296 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0292 | 0.1004 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0795 | 0.2337 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0009 | 0.0253 | 0.0218 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0292 | 0.0947 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0292 | 0.0292 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0008 | 0.0149 | 0.0085 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.001 | 0.0276 | 0.1104 |
Onchocerca volvulus | 0.001 | 0.0292 | 0.0958 | |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0292 | 0.0292 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0018 | 0.0795 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0292 | 0.1004 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0253 | 0.0253 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.082 | 0.0944 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0292 | 0.0947 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0129 | 0.7884 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0116 | 0.706 | 0.8943 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.001 | 0.0276 | 0.0164 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0276 | 0.2332 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0292 | 0.1004 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0292 | 0.0947 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0149 | 0.0085 |
Brugia malayi | DKFZp564C0469 protein | 0.001 | 0.0276 | 0.0895 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1296 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0292 | 0.0292 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0292 | 0.0947 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1296 | 0.42 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0149 | 0.0484 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.2911 | 1 |
Echinococcus multilocularis | nibrin | 0.001 | 0.0276 | 0.0949 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0886 | 0.2667 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.1296 | 0.6636 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1296 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0292 | 0.1004 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0292 | 0.0947 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0276 | 0.2332 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.2911 | 0.9431 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.0276 | 0.2332 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0795 | 0.1986 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.001 | 0.0276 | 0.0895 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0292 | 0.0947 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.0276 | 0.0949 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.164 | 0.5312 |
Echinococcus multilocularis | expressed protein | 0.0009 | 0.0253 | 0.087 |
Trichomonas vaginalis | ferritin, putative | 0.0009 | 0.0253 | 0.1995 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1878 | 1 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0253 | 0.0253 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.0276 | 0.2332 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.1296 | 0.42 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0161 | 0.0554 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.1296 | 0.42 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0497 | 0.161 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0292 | 0.1004 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0795 | 0.0912 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0795 | 0.2337 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0276 | 0.2332 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.2007 | 0.6501 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.1296 | 0.42 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0292 | 0.0947 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.2911 | 1 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0009 | 0.0253 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0292 | 0.0947 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.3087 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0886 | 0.6421 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0276 | 0.2332 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0292 | 0.0947 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0018 | 0.0795 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0149 | 0.046 |
Treponema pallidum | NADH oxidase | 0.0018 | 0.0795 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0161 | 0.0554 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0009 | 0.0253 | 0.0906 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0795 | 0.1986 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.082 | 0.0944 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0018 | 0.0795 | 1 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.001 | 0.0276 | 0.0895 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0008 | 0.0149 | 0.0085 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0253 | 0.0253 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1878 | 0.6083 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0292 | 0.0947 |
Loa Loa (eye worm) | oxidoreductase | 0.0008 | 0.0149 | 0.0484 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0276 | 0.0459 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0116 | 0.706 | 0.8943 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0276 | 0.2332 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0009 | 0.0253 | 0.0134 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.1296 | 0.1555 |
Echinococcus granulosus | ferritin | 0.0009 | 0.0253 | 0.087 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0753 | 0.2439 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Plasmodium falciparum | glutathione reductase | 0.0018 | 0.0795 | 0.2337 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0753 | 0.0753 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0292 | 0.0947 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0886 | 0.287 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0253 | 0.0253 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.1752 | 0.6018 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0292 | 0.1004 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0292 | 0.1004 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0753 | 0.2587 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.2007 | 0.6501 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Treponema pallidum | DNA ligase (lig) | 0.001 | 0.0276 | 0.0421 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0281 | 0.0911 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0161 | 0.0161 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0753 | 0.2587 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0008 | 0.0149 | 0.0484 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0008 | 0.0149 | 0.0514 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.2911 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0753 | 0.0753 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.001 | 0.0276 | 0.0459 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0161 | 0.0554 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0292 | 0.0947 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0795 | 0.2337 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1296 | 0.4153 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0886 | 0.287 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0009 | 0.0253 | 0.0906 |
Plasmodium falciparum | thioredoxin reductase | 0.0018 | 0.0795 | 0.2337 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0292 | 0.0947 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0292 | 0.1004 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0129 | 0.7884 | 1 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.001 | 0.0276 | 0.0459 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.1752 | 0.6018 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0276 | 0.0276 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0018 | 0.0795 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0008 | 0.0149 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0008 | 0.0149 | 0.0149 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1296 | 0.4153 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0018 | 0.0795 | 1 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0253 | 0.0253 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.1878 | 0.1878 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | topoisomerase | 0.001 | 0.0276 | 0.0895 |
Echinococcus multilocularis | ferritin | 0.0009 | 0.0253 | 0.087 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.2911 | 0.3625 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.1878 | 0.645 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0292 | 0.1004 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.1296 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.2911 | 1 |
Brugia malayi | glutathione reductase | 0.0051 | 0.2911 | 0.9431 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0753 | 0.2587 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0886 | 0.2667 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0795 | 0.5627 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0292 | 0.0947 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0292 | 0.0947 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0018 | 0.0795 | 0.2337 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0292 | 0.0947 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.1296 | 0.1555 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0753 | 0.2439 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0292 | 0.1004 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.2911 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0292 | 0.0947 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0116 | 0.706 | 0.8943 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0116 | 0.706 | 0.8943 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.001 | 0.0276 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0276 | 0.0895 |
Echinococcus granulosus | nibrin | 0.001 | 0.0276 | 0.0949 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0018 | 0.0795 | 0.8507 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0886 | 0.1029 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0795 | 0.0795 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0292 | 0.0947 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.1296 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0116 | 0.706 | 0.8934 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0292 | 0.1004 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0292 | 0.0947 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0008 | 0.0149 | 0.0514 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0292 | 0.1004 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.2911 | 0.9431 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0795 | 0.2337 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.1752 | 0.1752 |
Schistosoma mansoni | topbp1 | 0.001 | 0.0276 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0886 | 0.287 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1296 | 0.42 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0253 | 0.0253 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.1296 | 1 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0008 | 0.0149 | 0.0085 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0008 | 0.0149 | 0.046 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0292 | 0.0947 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1878 | 1 |
Onchocerca volvulus | 0.0026 | 0.1296 | 0.7697 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1878 | 1 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0276 | 0.2332 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0292 | 0.0947 |
Entamoeba histolytica | hypothetical protein | 0.001 | 0.0276 | 0.0733 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0292 | 0.0292 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0292 | 0.0292 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.3399 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0008 | 0.0149 | 0.0085 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0292 | 0.0947 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.0149 | 0.0484 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0008 | 0.0149 | 0.0085 |
Mycobacterium tuberculosis | Probable reductase | 0.0116 | 0.706 | 0.8943 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0795 | 0.2337 |
Onchocerca volvulus | 0.0031 | 0.164 | 1 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1878 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0292 | 0.0947 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0795 | 0.2337 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1296 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.3087 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0161 | 0.0554 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.3845 | 0.3845 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.3087 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0253 | 0.0253 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0116 | 0.706 | 0.8943 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0129 | 0.7884 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0886 | 0.287 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.2911 | 0.9431 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0886 | 0.287 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.