Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | lamin | 0.0028 | 0.1058 | 0.041 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.2644 | 0.2644 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0023 | 0.0675 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0137 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.0675 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1016 | 0.1016 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0137 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0137 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0137 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0137 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0137 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0023 | 0.0675 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.2644 | 0.2111 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1058 | 0.1058 |
Schistosoma mansoni | lamin | 0.0028 | 0.1058 | 0.041 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.2644 | 0.2111 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Echinococcus multilocularis | acetylcholinesterase | 0.0137 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.1058 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0675 | 0.0675 |
Echinococcus multilocularis | acetylcholinesterase | 0.0137 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0137 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0028 | 0.1058 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.1058 | 0.1058 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.2644 | 0.2111 |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0675 | 0.0675 |
Echinococcus multilocularis | musashi | 0.0028 | 0.1058 | 0.041 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2644 | 0.2111 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.1058 | 0.1058 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0675 | 0.0675 |
Echinococcus granulosus | lamin | 0.0028 | 0.1058 | 0.041 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.2644 | 0.2644 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0023 | 0.0675 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0023 | 0.0675 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2644 | 0.2111 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.1058 | 0.041 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.1058 | 0.041 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0023 | 0.0675 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.2644 | 0.2111 |
Brugia malayi | Carboxylesterase family protein | 0.0137 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.1058 | 0.1058 |
Onchocerca volvulus | 0.0028 | 0.1058 | 1 | |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.1058 | 0.041 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.1058 | 0.1058 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.2644 | 0.2111 |
Brugia malayi | Carboxylesterase family protein | 0.0023 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0675 | 0.0675 |
Onchocerca volvulus | 0.0028 | 0.1058 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0023 | 0.0675 | 0.0675 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.