Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.2063 | 0.2008 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.026 | 0.0354 |
Brugia malayi | nuclear receptor RXR | 0.006 | 0.0203 | 0.0277 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | nuclear receptor NHR-88 | 0.0114 | 0.0546 | 0.0745 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0114 | 0.0546 | 0.0546 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.057 | 0.3436 | 0.881 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0054 | 0.0162 | 0.0162 |
Schistosoma mansoni | P2X receptor subunit | 0.0385 | 0.2264 | 0.221 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Leishmania major | DNA polymerase eta, putative | 0.0049 | 0.013 | 0.0178 |
Loa Loa (eye worm) | cytochrome b5 reductase 4 | 0.0073 | 0.0283 | 0.0386 |
Schistosoma mansoni | P2X receptor subunit | 0.0385 | 0.2264 | 0.221 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0054 | 0.0162 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.026 | 0.027 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Echinococcus granulosus | NADH cytochrome b5 reductase 3 | 0.0073 | 0.0283 | 0.0283 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0385 | 0.2264 | 0.2264 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0114 | 0.0546 | 0.0745 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0114 | 0.0546 | 0.0568 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0114 | 0.0546 | 0.0745 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.026 | 0.0192 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.026 | 0.0192 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0643 | 0.39 | 0.3858 |
Leishmania major | p450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Schistosoma mansoni | P2X receptor subunit | 0.0385 | 0.2264 | 0.221 |
Leishmania major | oxidoreductase-like protein | 0.0073 | 0.0283 | 0.0386 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0246 | 0.138 | 0.3538 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0246 | 0.138 | 0.3538 |
Leishmania major | nitrate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0246 | 0.138 | 0.1883 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.006 | 0.0203 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0054 | 0.0162 | 0.0221 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0054 | 0.0162 | 0.0168 |
Mycobacterium tuberculosis | Possible oxygenase | 0.0073 | 0.0283 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0049 | 0.013 | 0.0062 |
Echinococcus granulosus | geminin | 0.0353 | 0.2063 | 0.2063 |
Leishmania major | NADH-dependent fumarate reductase-like protein | 0.0073 | 0.0283 | 0.0386 |
Echinococcus multilocularis | cytochrome b5 reductase 4 | 0.0073 | 0.0283 | 0.0294 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.1183 | 0.7328 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.1183 | 0.7328 | 0.7621 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.026 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0114 | 0.0546 | 0.0568 |
Schistosoma mansoni | nuclear hormone receptor | 0.0054 | 0.0162 | 0.0093 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0114 | 0.0546 | 0.048 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0114 | 0.0546 | 0.0745 |
Trypanosoma cruzi | oxidoreductase-protein, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Leishmania major | DNA polymerase eta, putative | 0.0034 | 0.0038 | 0.0051 |
Onchocerca volvulus | 0.0073 | 0.0283 | 0.3153 | |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0034 | 0.0038 | 0.0205 |
Schistosoma mansoni | cytochrome B5 | 0.0073 | 0.0283 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Trypanosoma brucei | oxidoreductase-protein, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0054 | 0.0162 | 0.0162 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0114 | 0.0546 | 0.048 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | nuclear hormone receptor | 0.0054 | 0.0162 | 0.0221 |
Brugia malayi | flavodoxin family protein | 0.0643 | 0.39 | 0.5322 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0114 | 0.0546 | 0.0745 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0114 | 0.0546 | 0.048 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0324 | 0.1875 | 0.1819 |
Schistosoma mansoni | nuclear receptor | 0.0054 | 0.0162 | 0.0093 |
Brugia malayi | FAD binding domain containing protein | 0.0397 | 0.2339 | 0.3192 |
Schistosoma mansoni | nuclear hormone receptor | 0.0114 | 0.0546 | 0.048 |
Plasmodium vivax | oxidoreductase NAD-binding domain containing protein | 0.0073 | 0.0283 | 0.0725 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0054 | 0.0162 | 0.0093 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0054 | 0.0162 | 0.0221 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0049 | 0.013 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0643 | 0.39 | 1 |
Leishmania major | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.026 | 0.0354 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0114 | 0.0546 | 0.0568 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0114 | 0.0546 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0353 | 0.2063 | 0.2008 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0034 | 0.0038 | 0.0051 |
Echinococcus granulosus | dna polymerase eta | 0.0049 | 0.013 | 0.013 |
Trypanosoma brucei | nitrate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0054 | 0.0162 | 0.0162 |
Toxoplasma gondii | ferredoxin NADP+ oxidoreductase FNR | 0.0073 | 0.0283 | 0.1534 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0137 | 0.0068 |
Brugia malayi | steroid hormone receptor | 0.0114 | 0.0546 | 0.0745 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0137 | 0.0143 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0643 | 0.39 | 0.4056 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0073 | 0.0283 | 0.5 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0385 | 0.2264 | 0.2354 |
Loa Loa (eye worm) | DR-78 | 0.0054 | 0.0162 | 0.0221 |
Brugia malayi | RNA binding protein | 0.0069 | 0.026 | 0.0354 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.026 | 0.0192 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0114 | 0.0546 | 0.0546 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.0203 | 0.0277 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0054 | 0.0162 | 0.0221 |
Brugia malayi | nuclear hormone receptor | 0.0114 | 0.0546 | 0.0745 |
Echinococcus granulosus | FTZ F1 alpha | 0.0114 | 0.0546 | 0.0546 |
Trypanosoma cruzi | p450 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0114 | 0.0546 | 0.0745 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0114 | 0.0546 | 0.0546 |
Echinococcus multilocularis | geminin | 0.0353 | 0.2063 | 0.2145 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0385 | 0.2264 | 0.2354 |
Schistosoma mansoni | P2X receptor subunit | 0.0385 | 0.2264 | 0.221 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.026 | 0.0192 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0643 | 0.39 | 1 |
Brugia malayi | diaphorase | 0.0073 | 0.0283 | 0.0386 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0114 | 0.0546 | 0.0568 |
Toxoplasma gondii | NADH-cytochrome b5 reductase 1, putative | 0.0073 | 0.0283 | 0.1534 |
Brugia malayi | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0137 | 0.0137 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | conserved hypotetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0385 | 0.2264 | 0.2264 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0114 | 0.0546 | 0.0568 |
Onchocerca volvulus | 0.0114 | 0.0546 | 1 | |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0643 | 0.39 | 0.5322 |
Brugia malayi | nuclear receptor RXR | 0.0054 | 0.0162 | 0.0221 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0054 | 0.0162 | 0.0221 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0069 | 0.0094 |
Plasmodium falciparum | ferredoxin--NADP reductase | 0.0073 | 0.0283 | 0.0725 |
Echinococcus multilocularis | NADH cytochrome b5 reductase 3 | 0.0073 | 0.0283 | 0.0294 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0114 | 0.0546 | 0.048 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Trypanosoma cruzi | nitrate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Schistosoma mansoni | NADH-cytochrome B5 reductase | 0.0073 | 0.0283 | 0.0215 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Leishmania major | reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0114 | 0.0546 | 0.048 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0069 | 0.0072 |
Plasmodium vivax | ferredoxin--NADP reductase, putative | 0.0073 | 0.0283 | 0.0725 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0114 | 0.0546 | 0.0546 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0114 | 0.0546 | 0.0745 |
Trypanosoma brucei | NADH-cytochrome b5 reductase-like protein | 0.0073 | 0.0283 | 0.0386 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0114 | 0.0546 | 1 |
Trypanosoma cruzi | reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Plasmodium vivax | hypothetical protein, conserved | 0.0246 | 0.138 | 0.3538 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1603 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.006 | 0.0203 | 0.0277 |
Echinococcus granulosus | methionine synthase reductase | 0.0397 | 0.2339 | 0.2339 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0114 | 0.0546 | 0.0745 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0319 | 0.1844 | 0.1787 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0246 | 0.138 | 0.3538 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.1183 | 0.7328 | 1 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0246 | 0.138 | 0.3538 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0643 | 0.39 | 0.5322 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.1183 | 0.7328 | 1 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0246 | 0.138 | 0.1883 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.006 | 0.0203 | 0.0211 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | flavodoxin family protein | 0.0246 | 0.138 | 0.1883 |
Loa Loa (eye worm) | hypothetical protein | 0.0643 | 0.39 | 0.5322 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.1183 | 0.7328 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0054 | 0.0162 | 0.0221 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0685 | 0.4166 | 0.4332 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.026 | 0.0354 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.1183 | 0.7328 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0385 | 0.2264 | 0.2264 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0114 | 0.0546 | 0.0745 |
Leishmania major | cytochrome P450 reductase, putative | 0.057 | 0.3436 | 0.4689 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0137 | 0.0187 |
Brugia malayi | ecdysone receptor | 0.0054 | 0.0162 | 0.0221 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0049 | 0.013 | 0.0178 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0073 | 0.0283 | 0.0386 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0246 | 0.138 | 0.1883 |
Mycobacterium tuberculosis | Probable monooxygenase | 0.0073 | 0.0283 | 0.5 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0073 | 0.0283 | 0.0283 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.057 | 0.3436 | 1 |
Plasmodium falciparum | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0725 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.006 | 0.0203 | 0.0277 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0685 | 0.4166 | 0.4166 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0137 | 0.0187 |
Brugia malayi | Cytochrome b5-like Heme/Steroid binding domain containing protein | 0.0073 | 0.0283 | 0.0386 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0319 | 0.1844 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0137 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0069 | 0.0069 |
Giardia lamblia | Hypothetical protein | 0.057 | 0.3436 | 1 |
Trypanosoma cruzi | p450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Schistosoma mansoni | coup transcription factor | 0.0114 | 0.0546 | 0.048 |
Echinococcus multilocularis | methionine synthase reductase | 0.0397 | 0.2339 | 0.2432 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0246 | 0.138 | 0.3538 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0246 | 0.138 | 0.1883 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0114 | 0.0546 | 0.0546 |
Treponema pallidum | flavodoxin | 0.0246 | 0.138 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.1183 | 0.7328 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | zinc finger protein | 0.0054 | 0.0162 | 0.0093 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0054 | 0.0162 | 0.0168 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0114 | 0.0546 | 0.0568 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0054 | 0.0162 | 0.0168 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0246 | 0.138 | 0.1883 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.1183 | 0.7328 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.1183 | 0.7328 | 0.7328 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0246 | 0.138 | 0.1883 |
Schistosoma mansoni | thyroid hormone receptor | 0.0114 | 0.0546 | 0.048 |
Brugia malayi | FAD binding domain containing protein | 0.0643 | 0.39 | 0.5322 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0114 | 0.0546 | 0.0745 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Leishmania major | hypothetical protein, conserved | 0.0246 | 0.138 | 0.1883 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0054 | 0.0162 | 0.0168 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0114 | 0.0546 | 0.048 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.026 | 0.0354 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0246 | 0.138 | 0.1883 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0643 | 0.39 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0114 | 0.0546 | 0.0745 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0073 | 0.0283 | 0.5 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0643 | 0.39 | 0.5322 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.006 | 0.0203 | 0.0203 |
Plasmodium vivax | flavodoxin domain containing protein | 0.057 | 0.3436 | 0.881 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0643 | 0.39 | 0.39 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0054 | 0.0162 | 0.0221 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0069 | 0.0094 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.026 | 0.026 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0114 | 0.0546 | 0.0546 |
Chlamydia trachomatis | sulfite reductase | 0.0397 | 0.2339 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0054 | 0.0162 | 0.0093 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0246 | 0.138 | 0.3538 |
Echinococcus multilocularis | dna polymerase eta | 0.0049 | 0.013 | 0.0136 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0246 | 0.138 | 0.1883 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0137 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0069 | 0.0094 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1543 | 0.9616 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0397 | 0.2339 | 0.2286 |
Mycobacterium tuberculosis | Hypothetical oxidoreductase | 0.0073 | 0.0283 | 0.5 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0319 | 0.1844 | 1 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0246 | 0.138 | 0.1883 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0054 | 0.0162 | 0.0221 |
Schistosoma mansoni | thyroid hormone receptor | 0.0114 | 0.0546 | 0.048 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0114 | 0.0546 | 0.0745 |
Giardia lamblia | Flavohemoprotein lateral transfer candidate | 0.0073 | 0.0283 | 0.0823 |
Schistosoma mansoni | nuclear receptor | 0.0054 | 0.0162 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.013 | 0.0178 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0069 | 0.0094 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0114 | 0.0546 | 0.0745 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0643 | 0.39 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0137 | 0.0143 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0073 | 0.0283 | 0.0283 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0049 | 0.013 | 0.0178 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0069 | 0.0094 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0643 | 0.39 | 0.39 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0114 | 0.0546 | 0.048 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0114 | 0.0546 | 0.0546 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.026 | 0.0354 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0054 | 0.0162 | 0.0162 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0397 | 0.2339 | 0.3192 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0114 | 0.0546 | 0.048 |
Brugia malayi | ecdysteroid receptor | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | tailless protein | 0.0054 | 0.0162 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0203 | 0.0277 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.1183 | 0.7328 | 0.731 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0114 | 0.0546 | 0.0745 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0073 | 0.0283 | 0.0386 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0385 | 0.2264 | 0.2354 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0054 | 0.0162 | 0.0162 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0054 | 0.0162 | 0.0221 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0162 | 0.0221 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0643 | 0.39 | 0.4056 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0137 | 0.0137 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0073 | 0.0283 | 0.0386 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0114 | 0.0546 | 0.0745 |
Brugia malayi | nuclear receptor NHR-67 | 0.0054 | 0.0162 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0546 | 0.0745 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0114 | 0.0546 | 0.0568 |
Brugia malayi | nuclear receptor NHR-88 | 0.0054 | 0.0162 | 0.0221 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0114 | 0.0546 | 0.0568 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0114 | 0.0546 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0114 | 0.0546 | 0.0568 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0054 | 0.0162 | 0.0162 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0114 | 0.0546 | 0.0745 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0246 | 0.138 | 0.1883 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0054 | 0.0162 | 0.0168 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.006 | 0.0203 | 0.0135 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0054 | 0.0162 | 0.0221 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0643 | 0.39 | 0.5322 |
Schistosoma mansoni | nuclear hormone receptor | 0.0054 | 0.0162 | 0.0093 |
Loa Loa (eye worm) | diaphorase | 0.0073 | 0.0283 | 0.0386 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0643 | 0.39 | 0.5322 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
logP (ADMET) | = 2.19 | Partition coefficient (logP) | ChEMBL. | 3625711 |
MIC (functional) | = 2 uM ml-1 | Antimicrobial activity against Streptococcus pyogenes A(IVM P 134) was determined | ChEMBL. | 3625711 |
MIC (functional) | = 3.2 uM ml-1 | Antimicrobial activity against Microsporum canis(ATCC 11621) was determined | ChEMBL. | 3625711 |
MIC (functional) | = 15 uM ml-1 | Antimicrobial activity against Staphylococcus aureus(ATCC 6538) was determined | ChEMBL. | 3625711 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.