Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.152 | 0.3642 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2557 | 0.2529 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2806 | 0.756 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1619 | 0.1587 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0325 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2806 | 0.756 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0744 | 0.0536 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0709 |
Onchocerca volvulus | 0.0029 | 0.152 | 0.5 | |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.1619 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1852 | 0.4652 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0744 | 0.1277 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.3607 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.3607 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0744 | 0.0536 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2557 | 0.2529 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0744 | 0.0536 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.2557 | 0.2529 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3607 | 0.3582 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0744 | 0.0536 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.022 | 0.0182 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0709 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2557 | 0.239 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0709 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1852 | 0.4663 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.152 | 0.1488 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.3607 | 0.3463 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.3068 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.1619 | 0.1431 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3607 | 0.3582 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2557 | 0.239 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.2557 | 0.239 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0744 | 0.0536 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.1619 | 0.1587 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3607 | 0.3582 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.152 | 0.3655 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2806 | 0.7566 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3607 | 0.3582 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.3607 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0325 | 0.0108 |
Echinococcus multilocularis | geminin | 0.0169 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.3607 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0744 | 0.1295 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0744 | 0.0536 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0744 | 0.1277 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3607 | 0.3582 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.2557 | 0.6809 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0744 | 0.1295 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.2557 | 0.6803 |
Brugia malayi | RNA binding protein | 0.0063 | 0.3607 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.2557 | 0.239 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0182 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.3607 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2806 | 0.7566 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.346 | 0.3435 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1852 | 0.1821 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0182 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0744 | 0.0709 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.3607 | 0.3463 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.