Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 1 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.237 | 0.237 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.237 | 0.1646 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.237 | 0.237 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.237 | 0.1646 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.237 | 0.237 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.237 | 0.237 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.237 | 0.237 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.237 | 0.237 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.237 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.237 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.237 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.237 | 0.1646 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.6333 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.237 | 0.237 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.237 | 0.237 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 1 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.237 | 0.237 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.6333 | 0.6333 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 1 | 1 |
Onchocerca volvulus | 0.0011 | 0 | 0.5 | |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.237 | 0.237 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.6333 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.237 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.237 | 0.1646 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.6333 | 0.6333 |
Brugia malayi | hypothetical protein | 0.0037 | 0.6333 | 0.6333 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 1 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.237 | 0.237 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.237 | 0.237 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 1 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.237 | 0.237 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.237 | 0.1646 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.237 | 0.1646 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.6333 | 0.6333 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.6333 | 0.6333 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.6333 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.6333 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.