Detailed information for compound 662562

Basic information

Technical information
  • TDR Targets ID: 662562
  • Name: 2-(4-bromophenyl)-N-(5-methyl-1,3-thiazol-2-y l)acetamide
  • MW: 311.198 | Formula: C12H11BrN2OS
  • H donors: 1 H acceptors: 2 LogP: 3.15 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ncc(s1)C)Cc1ccc(cc1)Br
  • InChi: 1S/C12H11BrN2OS/c1-8-7-14-12(17-8)15-11(16)6-9-2-4-10(13)5-3-9/h2-5,7H,6H2,1H3,(H,14,15,16)
  • InChiKey: XEMYTRCGCBAPHF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(4-bromophenyl)-N-(5-methylthiazol-2-yl)acetamide
  • 2-(4-bromophenyl)-N-(5-methyl-2-thiazolyl)acetamide
  • 2-(4-bromophenyl)-N-(5-methyl-1,3-thiazol-2-yl)ethanamide
  • Oprea1_158991
  • ZINC00475260
  • IVK/9311617
  • MLS001000909
  • SMR000497500

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear receptor subfamily 2, group E, member 3 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_135311 All targets in OG5_135311
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi photoreceptor-specific nuclear receptor Get druggable targets OG5_135311 All targets in OG5_135311
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Brugia malayi Nuclear hormone receptor family member nhr-49 nuclear receptor subfamily 2, group E, member 3 410 aa 384 aa 28.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0067 0.0183
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0067 0.0067
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0015 0.0099 0.0214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0663 0.0663
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0761 0.0761
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0099 0.0099
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0067 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0583 0.2351
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0433 0.4725
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0137 0.0137
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0067 0.0107
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0433 0.0433
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0179 0.0386
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0137 0.028
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0067 0.0116
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0067 0.0067
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0015 0.0099 0.0214
Loa Loa (eye worm) hypothetical protein 0.0037 0.041 0.0965
Mycobacterium ulcerans hypothetical protein 0.0049 0.0583 0.2351
Brugia malayi Doublecortin family protein 0.002 0.0179 0.0395
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0137 0.1499
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0099 0.0187
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0033 0.0351 0.1224
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0107 0.1377 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0351 0.0818
Loa Loa (eye worm) hypothetical protein 0.0015 0.0099 0.0187
Loa Loa (eye worm) ctsf protein 0.0017 0.0137 0.028
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0099 0.0196
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0433 0.5252
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0107 0.1377 0.6218
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0067 0.0067
Schistosoma mansoni coup transcription factor 0.0012 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0583 0.3914
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Entamoeba histolytica hypothetical protein 0.0073 0.0906 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0583 0.2351
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0067 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0067 0.0116
Loa Loa (eye worm) hypothetical protein 0.0015 0.0099 0.0187
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0099 0.0196
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0382 0.2376
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0067 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0805 1
Schistosoma mansoni hypothetical protein 0.002 0.0179 0.0179
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0672 0.2785
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0137 0.1499
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0067 0.0116
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0067 0.0067
Schistosoma mansoni loxhd1 0.002 0.0179 0.0179
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.1619 0.3997
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0067 0.0067
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0099 0.1901
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0583 0.1407
Brugia malayi Cathepsin L-like precursor 0.0017 0.0137 0.0289
Echinococcus multilocularis cpg binding protein 0.0031 0.033 0.033
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0307 0.0707
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0067 0.0067
Schistosoma mansoni jumonji domain containing protein 0.0123 0.1595 0.1595
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0067 0.0067
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0137 0.0137
Leishmania major cathepsin L-like protease 0.0017 0.0137 0.0526
Leishmania major cathepsin L-like protease 0.0017 0.0137 0.0526
Schistosoma mansoni jumonji domain containing protein 0.0033 0.0351 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Leishmania major cathepsin L-like protease 0.0017 0.0137 0.0526
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0433 0.0433
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.041 0.2589
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0179 0.0179
Brugia malayi jmjC domain containing protein 0.0033 0.0351 0.0827
Schistosoma mansoni lipoxygenase 0.0085 0.107 0.107
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0179 0.0739
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 1
Echinococcus multilocularis dnaJ subfamily B 0.042 0.5711 0.5711
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0163 0.2155 1
Onchocerca volvulus 0.002 0.0179 0.2304
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0067 0.0067
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0099 0.0099
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0067 0.0067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0025 0.0025
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0583 0.6846
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0137 0.0541
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0099 0.0214
Echinococcus granulosus JmjC domain containing protein 4 0.0033 0.0351 0.0351
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0107 0.1377 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0067 0.0067
Entamoeba histolytica cysteine protease, putative 0.0017 0.0137 0.1304
Echinococcus multilocularis phd:f box containing protein 0.0033 0.0351 0.0351
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Echinococcus multilocularis cysteine protease 0.0017 0.0137 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0067 0.0116
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0906 0.0906
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0058 0.0892
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0067 0.0067
Leishmania major cathepsin L-like protease 0.0066 0.0805 1
Schistosoma mansoni hypothetical protein 0.0073 0.0906 0.0906
Brugia malayi Cathepsin L-like precursor 0.0017 0.0137 0.0289
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0761 0.3221
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0583 0.6846
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Onchocerca volvulus 0.0017 0.0137 0.1499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Echinococcus granulosus cathepsin L cysteine protease 0.0009 0.0021 0.0021
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0033 0.0351 0.1224
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0099 0.0998
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Schistosoma mansoni cpg binding protein 0.0031 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0037 0.041 0.0965
Plasmodium vivax acetyl-CoA synthetase, putative 0.0015 0.0099 0.0367
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0382 0.2376
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0374 0.0374
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0067 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0663 0.0663
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0015 0.0099 0.0884
Brugia malayi hypothetical protein 0.002 0.0179 0.0395
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.0021 0.0021
Onchocerca volvulus 0.0017 0.0137 0.1499
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0583 0.2351
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0067 0.0183
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0663 0.0663
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0137 0.0137
Echinococcus multilocularis cathepsin L 0.0009 0.0021 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0583 0.6343
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0067 0.0107
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0179 0.0179
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0433 0.0433
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0583 0.6343
Onchocerca volvulus 0.0018 0.0154 0.1838
Loa Loa (eye worm) oxidoreductase 0.0015 0.0099 0.0187
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0433 0.5252
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.0021 0.0021
Plasmodium falciparum JmjC domain-containing protein, putative 0.0033 0.0351 0.1546
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Trypanosoma cruzi cruzipain precursor, putative 0.0066 0.0805 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0137 0.2802
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0761 0.5283
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0433 0.0433
Echinococcus granulosus cathepsin L 0.0009 0.0021 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Schistosoma mansoni microtubule-associated protein tau 0.073 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0137 0.028
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0663 0.1608
Loa Loa (eye worm) hypothetical protein 0.002 0.0179 0.0386
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0067 0.0107
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0067 0.0067
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0058 0.0092
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0009 0.0021 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0067 0.0107
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0163 0.2155 0.2155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0761 0.3221
Onchocerca volvulus 0.0012 0.0067 0.0183
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0099 0.0187
Loa Loa (eye worm) hypothetical protein 0.0037 0.041 0.0965
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0179 0.0179
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0033 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0067 0.0116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0906 0.0906
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0067 0.0067
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0015 0.0099 0.0367
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Brugia malayi Cathepsin L-like precursor 0.0017 0.0137 0.0289
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0382 0.2376
Echinococcus granulosus cathepsin l1 0.0017 0.0137 0.0137
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0067 0.0067
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0099 0.0998
Schistosoma mansoni rab6-interacting 0.002 0.0179 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0058 0.0892
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0067 0.0067
Brugia malayi jmjC domain containing protein 0.0124 0.1619 0.4003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0067 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0137 0.2802
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0067 0.0067
Onchocerca volvulus 0.0015 0.0099 0.0792
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0764 0.0764
Echinococcus multilocularis peptidase Clp (S14 family) 0.0107 0.1377 0.1377
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0015 0.0099 0.0998
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0099 0.0196
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0083
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0583 0.1407
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0583 0.1407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0163 0.2155 1
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0023 0.0005
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0433 0.0433
Loa Loa (eye worm) hypothetical protein 0.0163 0.2155 0.5341
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0179 0.0179
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0583 0.2351
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0351 0.0818
Schistosoma mansoni lipoxygenase 0.0121 0.1575 0.1575
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0137 0.0526
Onchocerca volvulus 0.0017 0.0137 0.1499
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0099 0.0998
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0067 0.0107
Echinococcus granulosus lysine specific demethylase 5A 0.0124 0.1619 0.1619
Echinococcus multilocularis jumonji domain containing 1A 0.0033 0.0351 0.0351
Brugia malayi Cathepsin L-like precursor 0.0017 0.0137 0.0289
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0351 0.4208
Loa Loa (eye worm) hypothetical protein 0.0039 0.0433 0.1023
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0761 0.3221
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0067 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0067 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Onchocerca volvulus 0.0017 0.0137 0.1499
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0583 0.2351
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0015 0.0099 0.0214
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0033 0.0351 0.4208
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0179 0.0179
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0137 0.028
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0433 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0123 0.1595 0.1595
Onchocerca volvulus 0.0049 0.0583 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0583 0.1399
Schistosoma mansoni cpg binding protein 0.0029 0.0307 0.0307
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0067 0.0116
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0067 0.0067
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0058 0.0058
Loa Loa (eye worm) doublecortin family protein 0.002 0.0179 0.0386
Echinococcus multilocularis microtubule associated protein 2 0.073 1 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0583 0.1399
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0137 0.1499
Brugia malayi Cathepsin L-like precursor 0.0017 0.0137 0.0289
Onchocerca volvulus 0.0015 0.0099 0.0792
Onchocerca volvulus 0.0017 0.0137 0.1499
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0099 0.0196
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0163 0.2155 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0137 0.0137
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0433 0.0433
Brugia malayi jmjC domain containing protein 0.0033 0.0351 0.0827
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0583 0.3914
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0015 0.0099 0.0214
Onchocerca volvulus 0.0017 0.0137 0.1499
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0433 0.1032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0015 0.0099 0.0214
Echinococcus granulosus cpg binding protein 0.0031 0.033 0.033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0099 0.0214
Brugia malayi Probable ClpP-like protease 0.0163 0.2155 0.5346
Schistosoma mansoni polycystin 1-related 0.002 0.0179 0.0179
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0906 0.0906
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0433 1
Onchocerca volvulus 0.0029 0.0307 0.4742
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0761 0.9381
Loa Loa (eye worm) hypothetical protein 0.0297 0.4012 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0067 0.0067
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0025 0.0025
Loa Loa (eye worm) fibroinase 0.0017 0.0137 0.028
Schistosoma mansoni peptidase Clp (S14 family) 0.0163 0.2155 0.2155
Loa Loa (eye worm) jmjC domain-containing protein 0.0033 0.0351 0.0818
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0163 0.2155 0.2155
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.1619 0.1619
Brugia malayi CXXC zinc finger family protein 0.0029 0.0307 0.0715
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0761 0.0761
Echinococcus granulosus phd:f box containing protein 0.0033 0.0351 0.0351
Echinococcus multilocularis cysteine protease 0.0017 0.0137 0.0137
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.041 0.151
Brugia malayi jmjC domain containing protein 0.0033 0.0351 0.0827
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0015 0.0099 0.0998
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0663 0.0663
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0583 0.2351
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0583 0.6343
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0137 0.0137
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0056 0.0676 0.3069
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.006 0.0726 0.8997
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0137 0.1304
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0433 0.4652
Toxoplasma gondii cathepsin CPL 0.0017 0.0137 0.0181
Loa Loa (eye worm) hypothetical protein 0.0049 0.0583 0.1399
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0433 0.0433
Brugia malayi jmjC domain containing protein 0.0123 0.1595 0.3944
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0099 0.0214
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0067 0.0067
Loa Loa (eye worm) cysteine protease 0.0017 0.0137 0.028
Brugia malayi nuclear receptor NHR-88 0.0012 0.0067 0.0116
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0583 0.2351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0433 0.5252
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0123 0.1595 0.1595
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0121 0.1575 0.1575
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0067 0.0067
Plasmodium vivax vivapain-2 0.0017 0.0137 0.0541
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0015 0.0099 0.0214
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0761 0.0761
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0663 0.0663
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0058 0.0415
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0433 0.0433
Echinococcus granulosus dnaJ subfamily B 0.042 0.5711 0.5711
Loa Loa (eye worm) hypothetical protein 0.0033 0.0351 0.0818
Trichomonas vaginalis antibiotic synthetase, putative 0.0015 0.0099 0.1901
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0067 0.0107
Brugia malayi jmjC domain containing protein 0.0033 0.0351 0.0827
Echinococcus multilocularis lysine specific demethylase 6a 0.0033 0.0351 0.0351
Leishmania major cathepsin L-like protease 0.0066 0.0805 1
Schistosoma mansoni cpg binding protein 0.0031 0.033 0.033
Brugia malayi cathepsin L-like precursor 0.0012 0.0058 0.0092
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0033 0.0351 0.4208
Loa Loa (eye worm) hypothetical protein 0.0033 0.0351 0.0818
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0137 0.2802
Leishmania major hypothetical protein, conserved 0.0033 0.0351 0.3566
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0067 0.0116
Echinococcus granulosus cysteine protease 0.0009 0.0021 0.0021
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0015 0.0099 0.0998
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0663 0.16
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0067 0.0107
Brugia malayi Cathepsin L-like precursor 0.0017 0.0137 0.0289
Schistosoma mansoni hypothetical protein 0.042 0.5711 0.5711
Echinococcus granulosus RUN 0.002 0.0179 0.0179
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0056 0.0676 0.3069
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0137 0.0137
Leishmania major cathepsin L-like protease 0.0066 0.0805 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0067 0.0116
Brugia malayi hypothetical protein 0.0073 0.0906 0.2218
Leishmania major cathepsin L-like protease 0.0017 0.0137 0.0526
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0611 0.7525
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0137 0.1472
Echinococcus multilocularis lysine specific demethylase 5A 0.0123 0.1595 0.1595
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0433 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0067 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0099 0.0196
Entamoeba histolytica hypothetical protein 0.0073 0.0906 1
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0099 0.0196
Brugia malayi ecdysteroid receptor 0.0012 0.0067 0.0116
Plasmodium vivax vivapain-2 0.0017 0.0137 0.0541
Leishmania major cathepsin L-like protease 0.0017 0.0137 0.0526
Plasmodium vivax JmjC domain containing protein 0.0033 0.0351 0.1546
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0067 0.0116
Loa Loa (eye worm) hypothetical protein 0.0033 0.0351 0.0818
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Onchocerca volvulus 0.0015 0.0099 0.0792
Schistosoma mansoni phosphatidylserine receptor 0.0033 0.0351 0.0351
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0761 0.3221
Brugia malayi Cathepsin L-like precursor 0.0012 0.0058 0.0092
Loa Loa (eye worm) hypothetical protein 0.0037 0.041 0.0965
Toxoplasma gondii hypothetical protein 0.0056 0.0676 0.2805
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0583 0.6846
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0099 0.0214
Brugia malayi nuclear hormone receptor 0.0012 0.0067 0.0116
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0382 0.2376
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0137 0.0541
Echinococcus multilocularis RUN 0.002 0.0179 0.0179
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0137 0.0541
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.041 0.1821
Echinococcus granulosus peptidase Clp S14 family 0.0107 0.1377 0.1377
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0137 0.0289
Brugia malayi Cathepsin L-like precursor 0.0012 0.0058 0.0092
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0121 0.1575 0.1575
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0015 0.0099 0.0214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0663 0.0663
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0179 0.0739
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0099 0.0099
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Echinococcus granulosus jumonji domain containing 1A 0.0033 0.0351 0.0351
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.041 0.1821
Entamoeba histolytica hypothetical protein 0.0073 0.0906 1
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0805 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0137 0.1304
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Brugia malayi photoreceptor-specific nuclear receptor 0.0297 0.4012 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0033 0.0351 0.0351
Schistosoma mansoni rab6-interacting 0.002 0.0179 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0067 0.0116
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0137 0.0137
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0067 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0663 0.0663
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Brugia malayi steroid hormone receptor 0.0012 0.0067 0.0116
Loa Loa (eye worm) hypothetical protein 0.0037 0.041 0.0965
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0433 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0163 0.2155 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0583 0.2351
Echinococcus granulosus lysine specific demethylase 6a 0.0033 0.0351 0.0351
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0067 0.0067
Trypanosoma cruzi cysteine peptidase, putative 0.0066 0.0805 1
Onchocerca volvulus 0.002 0.0179 0.2304
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0179 0.0179
Entamoeba histolytica hypothetical protein 0.0073 0.0906 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0583 0.2351
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0067 0.0067
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0137 0.0137
Schistosoma mansoni phd/f-box containing protein 0.0033 0.0351 0.0351
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0067 0.0067
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0067 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0137 0.2802
Schistosoma mansoni jumonji/arid domain-containing protein 0.0124 0.1619 0.1619
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0067 0.0116
Brugia malayi hypothetical protein 0.002 0.0179 0.0395
Loa Loa (eye worm) hypothetical protein 0.0012 0.0067 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0066 0.0805 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0163 0.2155 0.5
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0761 0.0761
Schistosoma mansoni protein phosphatase 2C 0.0033 0.0351 0.0351
Onchocerca volvulus 0.0017 0.0137 0.1499
Echinococcus granulosus cathepsin l1 0.0012 0.0058 0.0058
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0056 0.0676 0.2805
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0374 0.0374
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0067 0.0116

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 1.154 uM PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3). (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) 39.861 uM PubChem BioAssay. Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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