Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | dna polymerase eta | 0.0051 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.2319 | 0.2319 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.2319 | 0.2319 |
Leishmania major | DNA polymerase eta, putative | 0.0036 | 0.4775 | 0.4775 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0051 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0036 | 0.4775 | 0.4775 |
Brugia malayi | hypothetical protein | 0.0029 | 0.2319 | 0.2319 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.2319 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.2319 | 0.2319 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.2319 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0051 | 1 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0036 | 0.4775 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0051 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0051 | 1 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.2319 | 0.2319 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.2319 | 0.2319 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0022 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0051 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 0 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.2319 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.