Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0384 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.506 | 0.4863 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.2281 | 0.1973 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.5917 | 0.6385 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0384 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0384 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0384 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.2281 | 0.1973 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.506 | 0.4863 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.2281 | 0.1973 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.3278 | 0.334 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3278 | 0.301 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.2281 | 0.1973 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0384 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.5917 | 0.5754 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0152 | 0.905 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.506 | 0.4863 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0384 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0384 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.506 | 0.5396 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.3278 | 0.334 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.2281 | 0.1973 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0384 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.2281 | 0.1973 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0384 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0384 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0384 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.506 | 0.4863 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.3278 | 0.334 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3278 | 0.301 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.2281 | 0.2189 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0384 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0152 | 0.905 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3278 | 0.301 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.2281 | 0.1973 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2281 | 0.2189 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0384 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.5917 | 0.6385 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.506 | 0.4863 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.2281 | 0.2189 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.2281 | 0.1973 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0384 | 0.5 |
Echinococcus multilocularis | geminin | 0.0167 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.905 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.3278 | 0.301 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.3278 | 0.301 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.2281 | 0.1973 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0152 | 0.905 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3278 | 0.301 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0384 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.3278 | 0.301 |
Brugia malayi | RNA binding protein | 0.0063 | 0.3278 | 0.334 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.506 | 0.4863 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.3278 | 0.334 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.3278 | 0.334 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.2281 | 0.1973 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.506 | 0.5396 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.2281 | 0.2189 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0384 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0384 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.506 | 0.4863 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.