TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 584.791 | Formula: C36H48N4O3
H donors: 4 H acceptors: 1 LogP: 4.45 Rotable bonds: 18
Rule of 5 violations (Lipinski): 2
SMILES: NCCCCCCNC[C@@H]1N(CCc2c[nH]c3c2cccc3)[C@H](C([C@@H]1OCc1ccccc1)OCc1ccccc1)CO
InChi: 1S/C36H48N4O3/c37-20-11-1-2-12-21-38-24-33-35(42-26-28-13-5-3-6-14-28)36(43-27-29-15-7-4-8-16-29)34(25-41)40(33)22-19-30-23-39-32-18-10-9-17-31(30)32/h3-10,13-18,23,33-36,38-39,41H,1-2,11-12,19-22,24-27,37H2/t33-,34-,35+,36?/m0/s1
InChiKey: APLXSTNXAUTIFC-BZBLFYBUSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Rattus norvegicus	Somatostatin receptor	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Onchocerca volvulus		Somatostatin receptor	363 aa	325 aa	23.4 %
Onchocerca volvulus		Somatostatin receptor	363 aa	316 aa	21.5 %
Onchocerca volvulus		Somatostatin receptor	363 aa	318 aa	25.2 %
Schistosoma mansoni	neuropeptide F-like receptor	Somatostatin receptor	363 aa	295 aa	24.1 %
Schistosoma mansoni	peptide (allatostatin)-like receptor	Somatostatin receptor	363 aa	297 aa	27.9 %
Brugia malayi	GnHR receptor homolog	Somatostatin receptor	363 aa	352 aa	21.3 %
Onchocerca volvulus	Phospholipase d-related homolog	Somatostatin receptor	363 aa	295 aa	21.0 %
Onchocerca volvulus		Somatostatin receptor	363 aa	313 aa	24.0 %
Echinococcus multilocularis	allatostatin A receptor	Somatostatin receptor	363 aa	306 aa	31.7 %
Loa Loa (eye worm)	hypothetical protein	Somatostatin receptor	363 aa	291 aa	25.4 %
Onchocerca volvulus	E3 ubiquitin-protein ligase rpm-1 homolog	Somatostatin receptor	363 aa	347 aa	22.5 %
Echinococcus multilocularis	neuropeptide receptor	Somatostatin receptor	363 aa	344 aa	28.8 %
Echinococcus granulosus	thyrotropin releasing hormone receptor	Somatostatin receptor	363 aa	330 aa	27.0 %
Onchocerca volvulus		Somatostatin receptor	363 aa	331 aa	25.1 %
Schistosoma mansoni	adenoreceptor	Somatostatin receptor	363 aa	306 aa	26.5 %
Echinococcus multilocularis	g protein coupled receptor	Somatostatin receptor	363 aa	387 aa	21.2 %
Echinococcus granulosus	allatostatin A receptor	Somatostatin receptor	363 aa	301 aa	31.6 %
Schistosoma japonicum	ko:K04134 cholinergic receptor, invertebrate, putative	Somatostatin receptor	363 aa	314 aa	23.9 %
Schistosoma japonicum	ko:K04209 neuropeptide Y receptor, invertebrate, putative	Somatostatin receptor	363 aa	292 aa	27.4 %
Echinococcus multilocularis	thyrotropin releasing hormone receptor	Somatostatin receptor	363 aa	330 aa	27.3 %
Loa Loa (eye worm)	neuropeptide F receptor	Somatostatin receptor	363 aa	300 aa	26.7 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	nuclear receptor RXR	0.0101	0.1127	0.4173
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0192	0.2537	0.2537
Trypanosoma brucei	lipase domain protein, putative	0.0173	0.2242	0.5
Brugia malayi	steroid hormone receptor	0.0192	0.2537	0.9395
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0101	0.1127	0.1127
Schistosoma mansoni	RAR-like nuclear receptor	0.0192	0.2537	0.2537
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0192	0.2537	0.9395
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0202	0.27	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0192	0.2537	0.2537
Mycobacterium tuberculosis	4,9-DHSA hydrolase	0.0499	0.733	0.5
Trypanosoma cruzi	hypothetical protein, conserved	0.0173	0.2242	0.5
Echinococcus multilocularis	geminin	0.0165	0.2114	0.2114
Onchocerca volvulus		0.023	0.3136	1
Echinococcus granulosus	nuclear receptor nhr 48	0.009	0.0958	0.0958
Onchocerca volvulus		0.009	0.0958	0.3055
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.009	0.0958	0.0958
Schistosoma mansoni	coup transcription factor	0.0192	0.2537	0.2537
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0192	0.2537	0.2537
Echinococcus multilocularis	L aminoadipate semialdehyde	0.0082	0.0826	0.0826
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.009	0.0958	0.0958
Schistosoma mansoni	hypothetical protein	0.0035	0.0101	0.0101
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0921	0.3412
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1127	0.4173
Loa Loa (eye worm)	nuclear receptor NHR-67	0.009	0.0958	0.3547
Brugia malayi	nuclear hormone receptor	0.009	0.0958	0.3547
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0192	0.2537	0.9395
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1127	0.4173
Brugia malayi	hypothetical protein	0.009	0.0958	0.3547
Brugia malayi	orphan nuclear receptor NR2E1	0.009	0.0958	0.3547
Onchocerca volvulus	Protein ultraspiracle homolog	0.0192	0.2537	0.809
Echinococcus multilocularis	sn1 specific diacylglycerol lipase beta	0.0173	0.2242	0.2242
Onchocerca volvulus		0.0088	0.0921	0.2938
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0192	0.2537	0.9395
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.009	0.0958	0.3547
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0192	0.2537	0.9395
Schistosoma mansoni	hypothetical protein	0.0165	0.2114	0.2114
Echinococcus granulosus	ecdysone induced protein 78C	0.0192	0.2537	0.2537
Schistosoma mansoni	zinc finger protein	0.009	0.0958	0.0958
Schistosoma mansoni	hypothetical protein	0.0101	0.1126	0.1126
Echinococcus granulosus	sn1 specific diacylglycerol lipase beta	0.0173	0.2242	0.2242
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0192	0.2537	0.9395
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0192	0.2537	0.9395
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0088	0.0921	0.3412
Echinococcus multilocularis	FTZ F1 alpha	0.0192	0.2537	0.2537
Brugia malayi	Steroid receptor seven-up type 2	0.0192	0.2537	0.9395
Trichomonas vaginalis	set domain proteins, putative	0.023	0.3136	1
Schistosoma mansoni	microtubule-associated protein tau	0.067	1	1
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0192	0.2537	0.9395
Brugia malayi	nuclear hormone receptor	0.0192	0.2537	0.9395
Trypanosoma cruzi	hypothetical protein, conserved	0.0173	0.2242	0.5
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0192	0.2537	0.9395
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0192	0.2537	0.2537
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Brugia malayi	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	0.0082	0.0826	0.3059
Onchocerca volvulus		0.009	0.0958	0.3055
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0192	0.2537	0.2537
Echinococcus granulosus	L aminoadipate semialdehyde	0.0082	0.0826	0.0826
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1127	0.4173
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.009	0.0958	0.0958
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Brugia malayi	Lipase family protein	0.0173	0.2242	0.8302
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0192	0.2537	0.2537
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0192	0.2537	0.9395
Echinococcus granulosus	Nuclear hormone receptor HR96	0.009	0.0958	0.0958
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0192	0.2537	0.2537
Onchocerca volvulus	Bile acid receptor homolog	0.0192	0.2537	0.809
Brugia malayi	ecdysone receptor	0.009	0.0958	0.3547
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0192	0.2537	0.9395
Loa Loa (eye worm)	lipase	0.0173	0.2242	0.8302
Brugia malayi	Nuclear hormone receptor E75	0.009	0.0958	0.3547
Brugia malayi	Nuclear hormone receptor-like 1	0.0101	0.1127	0.4173
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0192	0.2537	0.2537
Brugia malayi	nuclear hormone receptor family member nhr-6	0.009	0.0958	0.3547
Schistosoma mansoni	nuclear hormone receptor	0.009	0.0958	0.0958
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0192	0.2537	0.2537
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0192	0.2537	0.9395
Brugia malayi	Nuclear hormone receptor-like 1	0.0192	0.2537	0.9395
Schistosoma mansoni	aminoadipate-semialdehyde dehydrogenase	0.0082	0.0826	0.0826
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0192	0.2537	0.9395
Brugia malayi	Pre-SET motif family protein	0.0202	0.27	1
Echinococcus multilocularis	ecdysone induced protein 78C	0.0192	0.2537	0.2537
Leishmania major	hypothetical protein, conserved	0.0173	0.2242	0.5
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0101	0.1127	0.1127
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0921	0.3412
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0192	0.2537	0.9395
Onchocerca volvulus		0.0082	0.0826	0.2634
Brugia malayi	nuclear hormone receptor family member odr-7	0.009	0.0958	0.3547
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0192	0.2537	0.2537
Schistosoma mansoni	sodium/chloride dependent transporter	0.0088	0.0921	0.0921
Brugia malayi	Nuclear hormone receptor-like 1	0.0101	0.1127	0.4173
Schistosoma mansoni	transcription factor LCR-F1	0.0035	0.0101	0.0101
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.009	0.0958	0.3547
Treponema pallidum	sodium- and chloride- dependent transporter	0.0088	0.0921	0.5
Schistosoma mansoni	nuclear receptor	0.009	0.0958	0.0958
Echinococcus multilocularis	nuclear receptor nhr 48	0.009	0.0958	0.0958
Brugia malayi	nuclear receptor NHR-88	0.009	0.0958	0.3547
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.009	0.0958	0.0958
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0192	0.2537	0.9395
Brugia malayi	ecdysteroid receptor	0.0192	0.2537	0.9395
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0192	0.2537	0.2537
Brugia malayi	tailless protein	0.009	0.0958	0.3547
Brugia malayi	hypothetical protein	0.0101	0.1127	0.4173
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0192	0.2537	0.2537
Echinococcus granulosus	thyroid hormone receptor alpha	0.009	0.0958	0.0958
Brugia malayi	conserved hypotetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	serotonin transporter b	0.0088	0.0921	0.3412
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0192	0.2537	0.2537
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Entamoeba histolytica	hypothetical protein	0.0035	0.0101	0.5
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1127	0.4173
Brugia malayi	nuclear receptor NHR-88	0.0192	0.2537	0.9395
Loa Loa (eye worm)	hypothetical protein	0.0082	0.0826	0.3059
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.009	0.0958	0.0958
Brugia malayi	Nuclear hormone receptor E75	0.009	0.0958	0.3547
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.009	0.0958	0.3055
Echinococcus multilocularis	microtubule associated protein 2	0.067	1	1
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.009	0.0958	0.3055
Brugia malayi	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	steroid hormone receptor	0.0192	0.2537	0.9395
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0192	0.2537	0.2537
Echinococcus granulosus	FTZ F1 alpha	0.0192	0.2537	0.2537
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0192	0.2537	0.9395
Plasmodium vivax	SET domain protein, putative	0.0029	0	0.5
Schistosoma mansoni	nuclear hormone receptor	0.009	0.0958	0.0958
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0101	0.1127	0.4173
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0192	0.2537	0.9395
Entamoeba histolytica	hypothetical protein	0.0035	0.0101	0.5
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0192	0.2537	0.2537
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0192	0.2537	0.2537
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.009	0.0958	0.0958
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0035	0.0101	0.0101
Trypanosoma brucei	lipase domain protein, putative	0.0173	0.2242	0.5
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0192	0.2537	0.9395
Echinococcus granulosus	expressed protein	0.0363	0.5201	0.5201
Loa Loa (eye worm)	DR-78	0.009	0.0958	0.3547
Entamoeba histolytica	hypothetical protein	0.0035	0.0101	0.5
Brugia malayi	photoreceptor-specific nuclear receptor	0.0192	0.2537	0.9395
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0192	0.2537	0.9395
Brugia malayi	hypothetical protein	0.0101	0.1127	0.4173
Schistosoma mansoni	hypothetical protein	0.0165	0.2114	0.2114
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0101	0.1127	0.1127
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.009	0.0958	0.0958
Schistosoma mansoni	nuclear receptor	0.009	0.0958	0.0958
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Entamoeba histolytica	hypothetical protein	0.0035	0.0101	0.5
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0035	0.0101	0.0101
Schistosoma mansoni	thyroid hormone receptor	0.0192	0.2537	0.2537
Schistosoma mansoni	nuclear hormone receptor	0.0192	0.2537	0.2537
Echinococcus multilocularis	expressed protein	0.0363	0.5201	0.5201
Schistosoma mansoni	retinoic acid receptor RXR	0.0192	0.2537	0.2537
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0192	0.2537	0.2537
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0192	0.2537	0.2537
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0029	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1127	0.4173
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0192	0.2537	0.2537
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.009	0.0958	0.0958
Onchocerca volvulus		0.0192	0.2537	0.809
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0192	0.2537	0.809
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Onchocerca volvulus		0.0173	0.2242	0.7149
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0192	0.2537	0.2537
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.009	0.0958	0.0958
Brugia malayi	nuclear receptor RXR	0.009	0.0958	0.3547
Brugia malayi	nuclear receptor NHR-67	0.009	0.0958	0.3547
Schistosoma mansoni	nuclear receptor nhr-48	0.009	0.0958	0.0958
Brugia malayi	hypothetical protein	0.0035	0.0101	0.0374
Schistosoma mansoni	thyroid hormone receptor	0.0192	0.2537	0.2537
Loa Loa (eye worm)	nuclear hormone receptor	0.009	0.0958	0.3547
Echinococcus granulosus	serotonin transporter	0.0088	0.0921	0.0921
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0192	0.2537	0.9395
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0921	0.3412
Loa Loa (eye worm)	solute carrier family 6 member 4	0.0088	0.0921	0.3412
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0101	0.1127	0.1127
Echinococcus granulosus	geminin	0.0165	0.2114	0.2114
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0192	0.2537	0.2537
Echinococcus granulosus	Nuclear hormone receptor HR96	0.009	0.0958	0.0958
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0088	0.0921	0.0921
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0192	0.2537	0.9395
Loa Loa (eye worm)	norepinephrine transporter	0.0088	0.0921	0.3412
Loa Loa (eye worm)	hypothetical protein	0.0192	0.2537	0.9395
Echinococcus multilocularis	serotonin transporter	0.0088	0.0921	0.0921
Mycobacterium ulcerans	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD	0.0507	0.7457	0.5
Loa Loa (eye worm)	hypothetical protein	0.009	0.0958	0.3547

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 14 uM	Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortex	ChEMBL.	No reference
IC50 (binding)	= 14 uM	Compound was tested for its potency to displace 3-[125I]- - Tyr11-SRIF-14 from somatostatin receptor on membranes of rat cerebral cortex	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 66570