Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.3521 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.3521 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0074 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2308 | 0.6071 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2308 | 0.6071 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.3521 | 0.7697 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.2477 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.8867 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0604 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.3521 | 1 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0604 | 0.0546 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0604 | 0.0546 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.3521 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.3521 | 1 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0604 | 0.0546 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.0604 | 0.5 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0604 | 0.0546 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.3521 | 0.7697 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.2477 | 0.6617 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0531 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.0074 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.3521 | 1 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.0604 | 0.0546 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4393 | 0.4331 |
Onchocerca volvulus | 0.0028 | 0.4393 | 1 | |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4393 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4393 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.3521 | 0.7697 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2477 | 0.4943 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0604 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0822 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.3521 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.3521 | 0.7697 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.3521 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.3521 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.092 | 0.0832 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2477 | 0.4943 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0074 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0604 | 0.5 |
Onchocerca volvulus | 0.0023 | 0.3521 | 0.7697 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2477 | 0.4943 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.3521 | 0.7697 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0604 | 0.0546 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.0074 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.3521 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.2477 | 1 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.0604 | 0.0546 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.0822 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.2477 | 0.5 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0007 | 0.0604 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.3521 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.3521 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0604 | 0.5 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.2477 | 0.6421 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.0604 | 0.0546 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.3521 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2308 | 0.6071 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.3521 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0525 | 0.8691 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4678 | 0.4619 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.3521 | 1 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0007 | 0.0604 | 0.05 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.3521 | 0.7697 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.3521 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.3521 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.3521 | 1 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.0604 | 0.0546 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0525 | 0.8691 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0007 | 0.0604 | 0.5 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.0604 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2477 | 0.4943 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4678 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0007 | 0.0604 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.2477 | 0.4943 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2308 | 0.6071 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0939 | 0.0884 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0525 | 0.8691 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4678 | 0.4619 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.0604 | 0.0546 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.