Detailed information for compound 668999

Basic information

Technical information
  • TDR Targets ID: 668999
  • Name: N-(2-chlorophenyl)-2-phenyl-2-phenylsulfanyla cetamide
  • MW: 353.865 | Formula: C20H16ClNOS
  • H donors: 1 H acceptors: 1 LogP: 5.66 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(c1ccccc1)Sc1ccccc1)Nc1ccccc1Cl
  • InChi: 1S/C20H16ClNOS/c21-17-13-7-8-14-18(17)22-20(23)19(15-9-3-1-4-10-15)24-16-11-5-2-6-12-16/h1-14,19H,(H,22,23)
  • InChiKey: UUSINBDCVHACIR-UHFFFAOYSA-N  

Network

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Synonyms

  • N-(2-chlorophenyl)-2-phenyl-2-phenylsulfanyl-acetamide
  • N-(2-chlorophenyl)-2-phenyl-2-(phenylthio)acetamide
  • N-(2-chlorophenyl)-2-phenyl-2-phenylsulfanyl-ethanamide
  • 4204-30-2
  • ST031874
  • Oprea1_133861

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0338 0.0338
Schistosoma mansoni amidase 0.0101 0.0508 0.0701
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.014 0.0748 0.0747
Mycobacterium leprae Probable methionyl-tRNA synthase MetS 0.0031 0.0084 0.1086
Loa Loa (eye worm) hypothetical protein 0.0237 0.134 0.3732
Trypanosoma cruzi replication Factor A 28 kDa subunit, putative 0.003 0.0078 0.0432
Trichomonas vaginalis helicase, putative 0.0019 0.0013 0.0018
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0011 0.0028
Schistosoma mansoni lysyl-tRNA synthetase 0.003 0.0078 0.0107
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0057 0.0281
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0011 0.0027
Echinococcus granulosus fatty acid amide hydrolase 1 0.0101 0.0508 0.0701
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0048 0.0249
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0201 0.0559
Onchocerca volvulus Peroxidasin homolog 0.0053 0.022 0.0685
Brugia malayi Peroxidasin 0.0053 0.022 0.0612
Onchocerca volvulus 0.0053 0.022 0.0685
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0017 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0137 0.0785
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0607 0.3589 1
Plasmodium falciparum lysine--tRNA ligase 0.003 0.0078 0.0407
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Leishmania major leucyl-tRNA synthetase, putative 0.0031 0.0084 0.0471
Onchocerca volvulus 0.002 0.0017 0.0053
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0026 0.0121
Brugia malayi mbt repeat family protein 0.005 0.0201 0.056
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0194 0.108 0.7263
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0031 0.0084 0.0518
Toxoplasma gondii hypothetical protein 0.0064 0.0284 0.1701
Entamoeba histolytica asparaginyl-tRNA synthetase, putative 0.003 0.0078 0.0486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Giardia lamblia Aspartyl-tRNA synthetase 0.003 0.0078 0.178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0201 0.0277
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0011 0.0012
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0137 1
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.003 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0201 0.0277
Brugia malayi Animal haem peroxidase family protein 0.0053 0.022 0.0612
Brugia malayi hypothetical protein 0.002 0.0017 0.0048
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0056 0.0055
Brugia malayi Serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0029 0.0074 0.0205
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0048 0.0065
Schistosoma mansoni hypothetical protein 0.014 0.0748 0.1031
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Giardia lamblia GTOR 0.0018 0.0006 0.0133
Chlamydia trachomatis methionine--tRNA ligase 0.0194 0.108 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0057 0.0281
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0785 0.4674 0.4673
Schistosoma mansoni hypothetical protein 0.1207 0.7248 1
Brugia malayi mbt repeat family protein 0.005 0.0201 0.056
Treponema pallidum leucyl-tRNA synthetase 0.0031 0.0084 0.0689
Toxoplasma gondii histone lysine methyltransferase SET1 0.0161 0.0874 0.5243
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0243 0.0678
Brugia malayi Animal haem peroxidase family protein 0.0053 0.022 0.0612
Schistosoma mansoni hypothetical protein 0.0035 0.011 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0137 0.0885
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Schistosoma mansoni rab6-interacting 0.002 0.0017 0.0023
Plasmodium vivax asparagine--tRNA ligase, putative 0.003 0.0078 0.0407
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0018 0.0006 0.0017
Brugia malayi Aspartyl-tRNA synthetase 0.003 0.0078 0.0217
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0338 0.0941
Brugia malayi hypothetical protein 0.002 0.0017 0.0048
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0412 0.1147
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Brugia malayi CXXC zinc finger family protein 0.0085 0.0412 0.1148
Schistosoma mansoni fatty-acid amide hydrolase 0.0101 0.0508 0.0701
Onchocerca volvulus 0.0048 0.019 0.0593
Brugia malayi beta-lactamase family protein 0.004 0.0137 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.003 0.0078 0.0107
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Echinococcus granulosus methionine tRNA synthetase 0.0031 0.0084 0.0116
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Schistosoma mansoni methionine-tRNA synthetase 0.0031 0.0084 0.0116
Brugia malayi Ets-domain containing protein 0.0073 0.0338 0.0942
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0048 0.0282
Schistosoma mansoni peroxidasin 0.0053 0.022 0.0302
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0006 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Brugia malayi lysyl-tRNA synthetase 0.003 0.0078 0.0217
Echinococcus multilocularis lysyl tRNA synthetase 0.003 0.0078 0.0078
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.022 0.0611
Onchocerca volvulus Peroxidase homolog 0.0053 0.022 0.0685
Schistosoma mansoni hypothetical protein 0.002 0.0017 0.0023
Brugia malayi hypothetical protein 0.0053 0.022 0.0612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.1121 0.1547
Wolbachia endosymbiont of Brugia malayi aspartyl-tRNA synthetase 0.003 0.0078 0.9137
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0011 0.0027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0011 0.0027
Entamoeba histolytica replication factor A, putative 0.0059 0.0254 0.1676
Plasmodium falciparum nucleic acid binding protein, putative 0.003 0.0078 0.0407
Plasmodium falciparum methionine--tRNA ligase 0.0031 0.0084 0.0445
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.022 0.0611
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0379
Schistosoma mansoni loxhd1 0.002 0.0017 0.0023
Plasmodium vivax replication protein A1, large subunit, putative 0.0291 0.1666 1
Schistosoma mansoni hypothetical protein 0.014 0.0748 0.1031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Echinococcus granulosus RUN 0.002 0.0017 0.0023
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0151 0.0815 0.227
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0137 0.0885
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0017 0.0017
Trichomonas vaginalis serine/threonine protein phosphatase, putative 0.0029 0.0074 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi notch-like transmembrane receptor 0.0017 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi methionyl-tRNA synthetase 0.0194 0.108 0.3008
Schistosoma mansoni rab6-interacting 0.002 0.0017 0.0023
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.022 0.0611
Schistosoma mansoni leucyl-tRNA synthetase 0.0031 0.0084 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Schistosoma mansoni mixed-lineage leukemia protein mll 0.018 0.0991 0.1366
Schistosoma mansoni protein phosphatase-1 0.0029 0.0074 0.0101
Brugia malayi BRCA2 repeat family protein 0.0122 0.0642 0.1788
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.014 0.0748 0.2083
Plasmodium falciparum asparagine--tRNA ligase 0.003 0.0078 0.0407
Schistosoma mansoni methionine-tRNA synthetase 0.0194 0.108 0.1489
Schistosoma mansoni hypothetical protein 0.003 0.0078 0.0107
Leishmania major aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Toxoplasma gondii tRNA ligases class I (M) protein 0.0031 0.0084 0.0504
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0011 0.003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0277 0.1582 0.2182
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0007 0.0001
Onchocerca volvulus Dual oxidase homolog 0.0053 0.022 0.0685
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0379
Loa Loa (eye worm) hypothetical protein 0.003 0.0078 0.0216
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Plasmodium falciparum methionine--tRNA ligase, putative 0.0031 0.0084 0.0445
Mycobacterium tuberculosis Conserved protein 0.004 0.0137 0.0885
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Brugia malayi Cadherin domain containing protein 0.0017 0.0001 0.0001
Brugia malayi Ets-domain containing protein 0.0073 0.0338 0.0942
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.0024 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0137 0.0364
Schistosoma mansoni ap endonuclease 0.0019 0.0011 0.0014
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Plasmodium vivax methionine--tRNA ligase, putative 0.0031 0.0084 0.0445
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0011 0.0012
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0277 0.1582 0.1581
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.003 0.0078 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Mycobacterium ulcerans lysyl-tRNA synthetase 0.003 0.0078 0.5348
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0029 0.0074 0.0073
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Mycobacterium ulcerans leucyl-tRNA synthetase 0.0031 0.0084 0.5853
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0013 0.0018
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0201 0.0277
Leishmania major replication Factor A 28 kDa subunit, putative 0.003 0.0078 0.0432
Echinococcus granulosus fatty acid amide hydrolase 1 0.0101 0.0508 0.0701
Echinococcus multilocularis glycyl tRNA synthetase 0.0151 0.0815 0.0815
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0277 0.1582 0.2182
Giardia lamblia Methionyl-tRNA synthetase 0.0031 0.0084 0.1926
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0006 0.0016
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0137 0.0885
Chlamydia trachomatis leucine--tRNA ligase 0.0031 0.0084 0.0063
Schistosoma mansoni protein phosphatase type 1 0.0029 0.0074 0.0101
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Mycobacterium leprae Probable lipase LipE 0.004 0.0137 1
Brugia malayi hypothetical protein 0.0026 0.0057 0.0159
Giardia lamblia Lysyl-tRNA synthetase 0.003 0.0078 0.178
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0243 0.0243
Brugia malayi Animal haem peroxidase family protein 0.0053 0.022 0.0612
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Echinococcus granulosus dnaJ subfamily B 0.1207 0.7248 1
Echinococcus granulosus cpg binding protein 0.009 0.0442 0.0609
Onchocerca volvulus 0.0085 0.0412 0.1286
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0622 0.0622
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.014 0.0748 0.1031
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0017 0.004
Giardia lamblia Hypothetical protein 0.0089 0.0436 1
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0243 0.0335
Plasmodium vivax asparagine--tRNA ligase, putative 0.003 0.0078 0.0407
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0234
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0048 0.0249
Mycobacterium ulcerans aspartyl-tRNA synthetase 0.003 0.0078 0.5348
Giardia lamblia Ser/Thr protein phosphatase PP1-alpha 2 catalytic subunit 0.0029 0.0074 0.1677
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0013 0.0018
Schistosoma mansoni ap endonuclease 0.0019 0.0011 0.0014
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Onchocerca volvulus 0.004 0.0137 0.0425
Leishmania major replication factor A, 51kDa subunit, putative 0.0291 0.1666 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.003 0.0078 0.5348
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Schistosoma mansoni gabp alpha 0.0073 0.0338 0.0466
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0024 0.0033
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0017 0.0023
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0243 0.0335
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0243 0.0243
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Loa Loa (eye worm) hypothetical protein 0.0057 0.0243 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Onchocerca volvulus 0.0053 0.022 0.0685
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0379
Loa Loa (eye worm) hypothetical protein 0.005 0.0201 0.0559
Entamoeba histolytica hypothetical protein 0.0025 0.0048 0.0279
Mycobacterium tuberculosis Conserved protein 0.004 0.0137 0.0885
Trichomonas vaginalis esterase, putative 0.004 0.0137 0.0364
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Mycobacterium tuberculosis Conserved protein 0.004 0.0137 0.0885
Onchocerca volvulus Chorion peroxidase homolog 0.0053 0.022 0.0685
Echinococcus multilocularis serine:threonine protein phosphatase PP1 gamma 0.0029 0.0074 0.0073
Onchocerca volvulus Peroxidasin homolog 0.0053 0.022 0.0685
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0072
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.003 0.0078 0.02
Loa Loa (eye worm) blistered cuticle protein 3 0.0053 0.022 0.0611
Echinococcus multilocularis cpg binding protein 0.009 0.0442 0.0441
Brugia malayi methionyl-tRNA synthetase 0.0031 0.0084 0.0235
Loa Loa (eye worm) replication factor A 73 kDa subunit 0.0607 0.3589 1
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0137 0.0885
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0057 0.0306
Schistosoma mansoni hypothetical protein 0.0308 0.1774 0.2447
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0201 0.0201
Leishmania major hypothetical protein, conserved 0.004 0.0137 0.0785
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.134 0.1848
Schistosoma mansoni hypothetical protein 0.014 0.0748 0.1031
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0029 0.0074 0.0101
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0031 0.0084 0.5853
Loa Loa (eye worm) hypothetical protein 0.0035 0.011 0.0305
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0137 0.0364
Plasmodium vivax serine/threonine protein phosphatase PP1, putative 0.0029 0.0074 0.038
Onchocerca volvulus 0.005 0.0201 0.0626
Echinococcus granulosus serine:threonine protein phosphatase PP1 beta 0.0029 0.0074 0.0101
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0277 0.1582 0.2182
Brugia malayi Serine/threonine protein phosphatase F56C9.1 in chromosomeIII 0.0029 0.0074 0.0205
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0031 0.0084 0.0234
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0017 0.0017
Brugia malayi Doublecortin family protein 0.002 0.0017 0.0048
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Loa Loa (eye worm) hypothetical protein 0.0194 0.108 0.3007
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0137 0.0885
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0031 0.0084 0.0218
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0209 0.0583
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.003 0.0078 0.0107
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0017 0.0023
Brugia malayi Serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0018 0.0006 0.0017
Giardia lamblia Asparaginyl-tRNA synthetase 0.003 0.0078 0.178
Echinococcus multilocularis dnaJ subfamily B 0.1207 0.7248 0.7248
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0013 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0137 0.0364
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0013 0.0018
Trichomonas vaginalis aspartyl/lysyl-tRNA synthetase, putative 0.003 0.0078 0.02
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Trypanosoma brucei protein phosphatase 1, putative 0.0029 0.0074 0.0405
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0006 0.0008
Schistosoma mansoni peroxidasin 0.0053 0.022 0.0302
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0078 0.0432
Loa Loa (eye worm) MBCTL1 0.0057 0.0243 0.0676
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0137 0.0885
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.003 0.0078 0.0078
Echinococcus multilocularis leucyl tRNA synthetase 0.0031 0.0084 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi Serine/threonine protein phosphatase PP1 isozyme 1, putative 0.0018 0.0006 0.0017
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0018 0.0006 0.0016
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0006 0.0016
Brugia malayi hypothetical protein 0.0237 0.134 0.3733
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0029 0.0074 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.019 0.053
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0011 0.001
Mycobacterium leprae conserved hypothetical protein 0.004 0.0137 1
Schistosoma mansoni protein phosphatase-1 0.0029 0.0074 0.0101
Toxoplasma gondii lysine-tRNA ligase 0.003 0.0078 0.0465
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0013 0.0018
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0201 0.0626
Schistosoma mansoni lysyl-tRNA synthetase 0.003 0.0078 0.0107
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi beta-lactamase 0.004 0.0137 0.0381
Loa Loa (eye worm) hypothetical protein 0.0062 0.0274 0.0762
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0137 0.0136
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0137 0.0785
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0013 0.0018
Brugia malayi Fli-1 protein 0.022 0.1238 0.345
Echinococcus multilocularis serine:threonine protein phosphatase PP1 isozyme 0.0029 0.0074 0.0073
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0006 0.0018
Brugia malayi Asparaginyl-tRNA synthetase, cytoplasmic 0.003 0.0078 0.0217
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0029 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.0158
Brugia malayi Cadherin domain containing protein 0.0017 0.0001 0.0001
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.014 0.0748 0.1031
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0011 0.003
Loa Loa (eye worm) doublecortin family protein 0.002 0.0017 0.0047
Plasmodium vivax methionine--tRNA ligase, putative 0.0031 0.0084 0.0445
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.1121 0.1121
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0101 0.0508 0.0508
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Plasmodium falciparum replication protein A1, large subunit 0.0291 0.1666 1
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0031 0.0084 0.0471
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.134 0.1339
Entamoeba histolytica hypothetical protein 0.003 0.0078 0.0486
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0006 0.0008
Entamoeba histolytica hypothetical protein 0.003 0.0078 0.0486
Brugia malayi Delta serrate ligand family protein 0.0017 0.0001 0.0001
Echinococcus multilocularis serine:threonine protein phosphatase PP1 beta 0.0029 0.0074 0.0073
Toxoplasma gondii OB-fold nucleic acid binding domain-containing protein 0.0152 0.0824 0.4943
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Treponema pallidum methionyl-tRNA synthetase 0.0194 0.108 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Treponema pallidum aspartyl-tRNA synthetase 0.003 0.0078 0.063
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Echinococcus granulosus lysyl tRNA synthetase 0.003 0.0078 0.0107
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0011 0.0014
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.0031 0.0084 1
Onchocerca volvulus 0.002 0.0017 0.0053
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.1434 1
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0018 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0581
Brugia malayi amidase 0.0101 0.0508 0.1417
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0031 0.0084 0.0471
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0151 0.0815 0.227
Toxoplasma gondii exonuclease III APE 0.0019 0.0011 0.0061
Mycobacterium ulcerans lipase LipD 0.004 0.0137 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0137 0.0379
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0338 0.0466
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0194 0.108 0.1079
Schistosoma mansoni polycystin 1-related 0.002 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0379
Loa Loa (eye worm) hypothetical protein 0.0031 0.0084 0.0234
Mycobacterium ulcerans hypothetical protein 0.004 0.0137 1
Schistosoma mansoni lipoxygenase 0.0119 0.0622 0.0858
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0054 0.0149
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0137 0.0188
Brugia malayi beta-lactamase family protein 0.004 0.0137 0.0381
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0137 0.0885
Loa Loa (eye worm) 63kd antigen 0.003 0.0078 0.0216
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0057 0.0281
Brugia malayi Animal haem peroxidase family protein 0.0053 0.022 0.0612
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0277 0.1582 0.2182
Echinococcus granulosus serine:threonine protein phosphatase PP1 gamma 0.0029 0.0074 0.0101
Echinococcus granulosus protein phosphatase 1, catalytic subunit, beta isozyme 0.0029 0.0074 0.0101
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Echinococcus multilocularis peroxidasin 0.0053 0.022 0.0219
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Leishmania major hypothetical protein, conserved 0.0026 0.0057 0.0306
Schistosoma mansoni glycyl-tRNA synthetase 0.0151 0.0815 0.1124
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0056 0.0153
Brugia malayi Animal haem peroxidase family protein 0.0053 0.022 0.0612
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0031 0.0084 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.0024 0.0033
Onchocerca volvulus 0.004 0.0137 0.0425
Trichomonas vaginalis protein phosphatase, caeel, putative 0.0029 0.0074 0.0188
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Echinococcus multilocularis asparaginyl tRNA synthetase 0.003 0.0078 0.0078
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0201 0.0277
Schistosoma mansoni hypothetical protein 0.0048 0.019 0.0262
Loa Loa (eye worm) hypothetical protein 0.0029 0.0074 0.0203
Brugia malayi Serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0018 0.0006 0.0017
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0048 0.0065
Echinococcus multilocularis replication protein A 70 kDa DNA binding 0.0607 0.3589 0.3589
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0013 0.0018
Toxoplasma gondii aspartate-tRNA ligase 0.003 0.0078 0.0465
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0137 0.0188
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0137 1
Onchocerca volvulus Peroxidase homolog 0.0053 0.022 0.0685
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0137 0.0785
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0209 0.0581
Toxoplasma gondii ABC1 family protein 0.004 0.0137 0.0817
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Plasmodium falciparum serine/threonine protein phosphatase PP1 0.0029 0.0074 0.038
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0277 0.1582 0.4407
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0194 0.108 0.1489
Schistosoma mansoni cpg binding protein 0.009 0.0442 0.0609
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0057 0.0306
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0006 0.0018
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0056 0.0076
Echinococcus multilocularis methionine tRNA synthetase 0.0031 0.0084 0.0084
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0209 0.0583
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0101 0.0508 0.0508
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0277 0.1582 0.4406
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.003 0.0078 0.0216
Brugia malayi putative serine/threonine phosphatase 0.0018 0.0006 0.0017
Leishmania major lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Brugia malayi glycyl-tRNA synthetase 0.0151 0.0815 0.2271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0163 0.0891 0.2482
Leishmania major serine/threonine protein phosphatase catalytic subunit, putative 0.0029 0.0074 0.0405
Schistosoma mansoni protein phosphatase type 1 0.0029 0.0074 0.0101
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0048 0.0047
Trypanosoma cruzi Replication factor A protein 1 0.0291 0.1666 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Loa Loa (eye worm) hypothetical protein 0.0059 0.0254 0.0706
Schistosoma mansoni survival motor neuron protein 0.0048 0.019 0.0262
Echinococcus granulosus replication protein A 70 kDa DNA binding 0.0607 0.3589 0.4952
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Brugia malayi GCC2 and GCC3 family protein 0.0017 0.0001 0.0001
Brugia malayi EGF-like domain containing protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) serine/threonine protein phosphatase PP1 isozyme 1 0.0018 0.0006 0.0016
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Schistosoma mansoni ets-related 0.022 0.1238 0.1708
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0011 0.0027
Schistosoma mansoni protein phosphatase-1 0.0018 0.0006 0.0008
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0006 0.0035
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-beta catalytic subunit 0.0029 0.0074 0.0203
Treponema pallidum asparaginyl-tRNA synthetase 0.003 0.0078 0.063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Schistosoma mansoni cpg binding protein 0.009 0.0442 0.0609
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0577 0.3407 0.9492
Trypanosoma brucei Replication factor A protein 1 0.0291 0.1666 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.003 0.0078 0.0407
Schistosoma mansoni protein phosphatase-1 0.0018 0.0006 0.0008
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0785 0.4674 0.6448
Trichomonas vaginalis protein phosphatase-1, putative 0.0029 0.0074 0.0188
Entamoeba histolytica replication factor A protein 1, putative 0.0261 0.1484 1
Brugia malayi Blistered cuticle protein 3 0.0053 0.022 0.0612
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0016
Schistosoma mansoni aspartyl-tRNA synthetase 0.003 0.0078 0.0107
Plasmodium vivax lysine--tRNA ligase, putative 0.003 0.0078 0.0407
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0201 0.0277
Echinococcus multilocularis protein phosphatase 1 catalytic subunit 0.0029 0.0074 0.0073
Trypanosoma cruzi serine/threonine protein phosphatase catalytic subunit, putative 0.0029 0.0074 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0048 0.0115
Loa Loa (eye worm) BRCA2 repeat family protein 0.0122 0.0642 0.1787
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-gamma catalytic subunit 0.0018 0.0006 0.0016
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0006 0.0006
Toxoplasma gondii methionyl-tRNA synthetase 0.0031 0.0084 0.0504
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0013 0.0018
Schistosoma mansoni replication factor A 1 rfa1 0.0607 0.3589 0.4952
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0001 0.0001
Toxoplasma gondii serine/threonine phosophatase PP1 0.0029 0.0074 0.0438
Loa Loa (eye worm) hypothetical protein 0.0053 0.022 0.0611
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0013 0.0018
Leishmania major aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Loa Loa (eye worm) beta-lactamase 0.004 0.0137 0.0379
Echinococcus granulosus peroxidasin 0.0053 0.022 0.0302
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0543 0.3201 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0047
Onchocerca volvulus Putative replication factor A 73 kDa subunit 0.0059 0.0254 0.0792
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0201 0.0201
Onchocerca volvulus 0.004 0.0137 0.0425
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Loa Loa (eye worm) apoptosis regulator protein 0.014 0.0748 0.2082
Giardia lamblia Leucyl-tRNA synthetase 0.0031 0.0084 0.1926
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.022 0.0611
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.003 0.0078 0.0473
Brugia malayi protein ZK524.3 0.0031 0.0084 0.0235
Plasmodium falciparum asparagine--tRNA ligase 0.003 0.0078 0.0407
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0277 0.1582 0.1581
Entamoeba histolytica aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0486
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0277 0.1582 0.2182
Loa Loa (eye worm) hypothetical protein 0.014 0.0748 0.2082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Schistosoma mansoni protein phosphatase type 1 0.0018 0.0006 0.0008
Loa Loa (eye worm) serine/threonine protein phosphatase PP1-alpha catalytic subunit 0.0018 0.0006 0.0016
Plasmodium vivax hypothetical protein, conserved 0.004 0.0137 0.076
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0017 0.004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0137 0.0381
Toxoplasma gondii replication factor-a protein 1 (rpa1) subfamily protein 0.0291 0.1666 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0011 0.0234
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.003 0.0078 0.0078
Schistosoma mansoni cpg binding protein 0.0085 0.0412 0.0568
Loa Loa (eye worm) hypothetical protein 0.004 0.0137 0.0379
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0607 0.3589 1
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0057 0.034
Echinococcus granulosus protein phosphatase 1 catalytic subunit 0.0029 0.0074 0.0101
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0137 0.0188
Leishmania major asparaginyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Echinococcus multilocularis RUN 0.002 0.0017 0.0017
Trichomonas vaginalis bsu-protein phosphatase, putative 0.0029 0.0074 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.003 0.0078 0.0473
Schistosoma mansoni lipoxygenase 0.0083 0.0404 0.0556
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0006 0.0006
Brugia malayi Muscle positioning protein 4 0.0017 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0243 0.0335
Onchocerca volvulus 0.0053 0.022 0.0685
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0137 0.0364
Trichomonas vaginalis replication factor A 1, rfa1, putative 0.0291 0.1666 0.4633
Trypanosoma cruzi aspartyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Loa Loa (eye worm) fli-1 protein 0.022 0.1238 0.3449
Schistosoma mansoni apoptosis regulator bax 0.014 0.0748 0.1031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0048 0.0132
Brugia malayi replication factor A 73 kDa subunit 0.0607 0.3589 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0622 0.0858
Echinococcus granulosus glycyl tRNA synthetase 0.0151 0.0815 0.1124
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0151 0.0815 0.2271
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0137 0.0364
Leishmania major lysyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0084 0.0445
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0006 0.0008
Plasmodium falciparum aspartate--tRNA ligase 0.003 0.0078 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Mycobacterium ulcerans beta-lactamase 0.004 0.0137 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0508 0.1415
Trypanosoma cruzi asparaginyl-tRNA synthetase, putative 0.003 0.0078 0.0432
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.011 0.0306
Plasmodium vivax aspartate--tRNA ligase, putative 0.003 0.0078 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0006 0.0000082148
Leishmania major methionyl-tRNA synthetase, putative 0.0031 0.0084 0.0471
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0057 0.0306

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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