Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0048 | 0.0083 | 0.0253 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0056 | 0.01 | 0.01 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0126 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0189 | 0.0188 |
Echinococcus multilocularis | aminopeptidase N | 0.0224 | 0.044 | 0.1327 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0026 | 0.004 | 0.0122 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0025 | 0.0036 | 0.0111 |
Echinococcus granulosus | sodium:hydrogen exchanger | 0.0016 | 0.0019 | 0.0041 |
Echinococcus multilocularis | nervana 2 | 0.001 | 0.0007 | 0.0004 |
Giardia lamblia | Kinase, AGC PKA | 0.001 | 0.0007 | 0.0385 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.001 | 0.0006 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0014 | 0.0014 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.004 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0131 | 0.013 |
Brugia malayi | hypothetical protein | 0.0126 | 0.0242 | 0.0242 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.01 | 0.0189 | 0.0559 |
Brugia malayi | hypothetical protein | 0.01 | 0.0189 | 0.0189 |
Onchocerca volvulus | 0.0126 | 0.0242 | 0.5445 | |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.002 | 0.0027 | 0.1113 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0011 | 0.0008 | 0.0007 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.001 | 0.0007 | 0.0304 |
Toxoplasma gondii | aminopeptidase n, putative | 0.01 | 0.0189 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0018 | 0.0018 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0054 | 0.0147 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.001 | 0.0007 | 0.0085 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0126 | 0.0242 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0023 | 0.0033 | 0.0101 |
Onchocerca volvulus | 0.0224 | 0.044 | 1 | |
Echinococcus granulosus | GA binding protein alpha chain | 0.007 | 0.0128 | 0.0374 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0189 | 0.0188 |
Echinococcus granulosus | aminopeptidase N | 0.0224 | 0.044 | 0.1327 |
Entamoeba histolytica | protein kinase, putative | 0.0016 | 0.0018 | 0.0739 |
Brugia malayi | Serotonin receptor | 0.0433 | 0.0862 | 0.0862 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0013 | 0.0013 | 0.0022 |
Onchocerca volvulus | 0.01 | 0.0189 | 0.4213 | |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0126 | 0.0242 | 0.0739 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.1626 | 0.3278 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0522 | 0.1043 | 0.3183 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.01 | 0.0189 | 0.7409 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.002 | 0.0027 | 0.1113 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.001 | 0.0007 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.1626 | 0.3278 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0238 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0131 | 0.013 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0036 | 0.1475 |
Echinococcus multilocularis | nervana 2 | 0.001 | 0.0007 | 0.0004 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.01 | 0.0189 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0036 | 0.1636 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0048 | 0.0083 | 0.0253 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0114 | 0.033 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0126 | 0.0242 | 0.0723 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.01 | 0.0189 | 1 |
Giardia lamblia | Kinesin-5 | 0.0027 | 0.0041 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0056 | 0.01 | 0.5 |
Toxoplasma gondii | AGC kinase | 0.0016 | 0.0018 | 0.0662 |
Schistosoma mansoni | transient receptor potential channel | 0.0073 | 0.0135 | 0.0412 |
Schistosoma mansoni | endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) | 0.0023 | 0.0033 | 0.0101 |
Schistosoma mansoni | ets-related | 0.001 | 0.0007 | 0.0021 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.001 | 0.0007 | 0.0004 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0016 | 0.0019 | 0.0018 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.001 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.001 | 0.0006 | 0.0005 |
Loa Loa (eye worm) | aminopeptidase N | 0.0126 | 0.0242 | 0.0242 |
Echinococcus granulosus | kinesin family 1 | 0.0208 | 0.0408 | 0.123 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.001 | 0.0006 | 0.0018 |
Entamoeba histolytica | protein kinase, putative | 0.0016 | 0.0019 | 0.0776 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0016 | 0.0019 | 0.0041 |
Trypanosoma cruzi | aminopeptidase, putative | 0.01 | 0.0189 | 0.7791 |
Brugia malayi | TATA binding protein associated factor | 0.01 | 0.0189 | 0.0189 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0016 | 0.0019 | 0.0041 |
Toxoplasma gondii | aminopeptidase N, putative | 0.01 | 0.0189 | 1 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0009 | 0.0004 | 0.0182 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.001 | 0.0006 | 0.0018 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0094 | 0.0178 | 0.0178 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0011 | 0.0008 | 0.0025 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0056 | 0.01 | 0.0307 |
Onchocerca volvulus | Sodium\/hydrogen exchanger homolog | 0.0016 | 0.0019 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0061 | 0.006 |
Echinococcus multilocularis | geminin | 0.0522 | 0.1043 | 0.3171 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.01 | 0.0189 | 0.0188 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0023 | 0.0033 | 0.0101 |
Schistosoma mansoni | transient receptor potential channel | 0.0073 | 0.0135 | 0.0413 |
Echinococcus multilocularis | kinesin family 1 | 0.0208 | 0.0408 | 0.123 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.001 | 0.0006 | 0.5 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0038 | 0.0063 | 0.0174 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0114 | 0.0347 |
Echinococcus granulosus | nervana 2 | 0.001 | 0.0007 | 0.0004 |
Echinococcus granulosus | geminin | 0.0522 | 0.1043 | 0.3171 |
Brugia malayi | hypothetical protein | 0.0741 | 0.1486 | 0.1486 |
Echinococcus granulosus | sodium:hydrogen exchanger | 0.0016 | 0.0019 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0054 | 0.0165 |
Entamoeba histolytica | protein kinase 2, putative | 0.001 | 0.0007 | 0.0304 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0054 | 0.0053 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 (nhe2) | 0.0013 | 0.0013 | 0.0022 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.001 | 0.0006 | 0.0018 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.001 | 0.0007 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0054 | 0.0165 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0126 | 0.0242 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0114 | 0.0113 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.001 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0128 | 0.0127 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0048 | 0.0083 | 0.0253 |
Echinococcus multilocularis | protein C ets 2 | 0.001 | 0.0007 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.001 | 0.0007 | 0.0004 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0126 | 0.0242 | 1 |
Loa Loa (eye worm) | D-ets-2 protein | 0.001 | 0.0007 | 0.0006 |
Schistosoma mansoni | ets | 0.001 | 0.0007 | 0.0021 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.007 | 0.0128 | 0.0127 |
Echinococcus multilocularis | sodium:hydrogen exchanger | 0.0016 | 0.0019 | 0.0041 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0114 | 0.0114 |
Brugia malayi | hypothetical protein | 0.001 | 0.0006 | 0.0006 |
Echinococcus granulosus | serotonin transporter | 0.0056 | 0.01 | 0.0289 |
Schistosoma mansoni | elf1 | 0.001 | 0.0007 | 0.0021 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0078 | 0.0239 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.001 | 0.0007 | 0.0004 |
Brugia malayi | Peptidase family M1 containing protein | 0.01 | 0.0189 | 0.0189 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.01 | 0.0189 | 0.0559 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0011 | 0.0008 | 0.034 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0094 | 0.0178 | 0.5 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0126 | 0.0242 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0016 | 0.0019 | 0.0776 |
Onchocerca volvulus | Sodium\/hydrogen exchanger homolog | 0.0016 | 0.0019 | 0.0308 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.001 | 0.0007 | 0.0021 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.01 | 0.0189 | 0.7791 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.01 | 0.0189 | 1 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.001 | 0.0006 | 0.0018 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0073 | 0.0135 | 0.0396 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.001 | 0.0006 | 0.0018 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0038 | 0.0063 | 0.0191 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.001 | 0.0006 | 0.0006 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0078 | 0.0222 |
Brugia malayi | Ets-domain containing protein | 0.007 | 0.0128 | 0.0128 |
Schistosoma mansoni | neprilysin | 0.0025 | 0.0036 | 0.0111 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0126 | 0.0242 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0054 | 0.0147 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.1626 | 0.3278 | 1 |
Onchocerca volvulus | 0.0056 | 0.01 | 0.218 | |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0094 | 0.0178 | 0.0542 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0178 | 0.0177 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0013 | 0.0013 | 0.0021 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.001 | 0.0007 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0184 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0132 | 0.0404 |
Toxoplasma gondii | aminopeptidase N protein | 0.01 | 0.0189 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0013 | 0.0013 | 0.0013 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Schistosoma mansoni | ets-related | 0.0212 | 0.0416 | 0.1271 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.001 | 0.0007 | 0.0006 |
Loa Loa (eye worm) | sodium/hydrogen exchanger 3 family protein | 0.0016 | 0.0019 | 0.0018 |
Brugia malayi | Fli-1 protein | 0.0212 | 0.0416 | 0.0416 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0016 | 0.0018 | 0.0017 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0048 | 0.0083 | 0.0253 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.01 | 0.0189 | 0.7791 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0016 | 0.0018 | 0.0018 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.001 | 0.0007 | 0.0004 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0114 | 0.0114 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.001 | 0.0007 | 0.0004 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0073 | 0.0135 | 0.0396 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0078 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.0018 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0114 | 0.0347 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.001 | 0.0007 | 0.0004 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0018 | 0.0022 | 0.0022 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.01 | 0.0189 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0114 | 0.033 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0019 | 0.0026 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | NHE-3 | 0.0016 | 0.0019 | 0.0018 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0126 | 0.0242 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0016 | 0.0019 | 0.0776 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 nhe2 | 0.0016 | 0.0019 | 0.0041 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0026 | 0.004 | 0.0104 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0054 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.01 | 0.01 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0011 | 0.0008 | 0.0007 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Schistosoma mansoni | hypothetical protein | 0.0522 | 0.1043 | 0.3183 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0128 | 0.0127 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.011 | 0.021 | 0.0624 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0078 | 0.0222 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.01 | 0.0189 | 0.7791 |
Echinococcus multilocularis | serotonin transporter | 0.0056 | 0.01 | 0.0289 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.007 | 0.0128 | 0.0127 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0036 | 0.1475 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0056 | 0.01 | 0.01 |
Loa Loa (eye worm) | zinc metallopeptidase 4 | 0.0023 | 0.0033 | 0.0032 |
Brugia malayi | sodium/hydrogen exchanger 3 family protein | 0.0016 | 0.0019 | 0.0019 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0126 | 0.0242 | 1 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.001 | 0.0007 | 0.0005 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0054 | 0.0054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0078 | 0.0239 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.01 | 0.0189 | 0.7791 |
Brugia malayi | Transient-receptor-potential like protein | 0.0042 | 0.0071 | 0.0071 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.011 | 0.021 | 0.064 |
Loa Loa (eye worm) | fli-1 protein | 0.0212 | 0.0416 | 0.0416 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0038 | 0.0063 | 0.0174 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.01 | 0.0189 | 0.1739 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0006 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0078 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.01 | 0.01 |
Brugia malayi | peptidase family M13 containing protein | 0.0023 | 0.0033 | 0.0033 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.002 | 0.0027 | 0.1113 |
Loa Loa (eye worm) | serotonin transporter b | 0.0056 | 0.01 | 0.01 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0036 | 0.1636 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0128 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0131 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.01 | 0.01 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0105 | 0.02 | 0.02 |
Brugia malayi | Peptidase family M1 containing protein | 0.0126 | 0.0242 | 0.0242 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Schistosoma mansoni | sodium/hydrogen exchanger | 0.0016 | 0.0019 | 0.0059 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.011 | 0.021 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0007 | 0.0006 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0126 | 0.0242 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0016 | 0.0019 | 0.0772 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.021 | 0.0209 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0048 | 0.0083 | 0.0253 |
Brugia malayi | Ets-domain containing protein | 0.001 | 0.0007 | 0.0007 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0027 | 0.0041 | 0.1938 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0081 | 0.008 |
Brugia malayi | transcription factor E74 isoform | 0.001 | 0.0007 | 0.0007 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0007 | 0.0021 |
Plasmodium vivax | kinesin-5 | 0.0027 | 0.0041 | 0.1938 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0011 | 0.0008 | 0.034 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0036 | 0.0111 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0054 | 0.0147 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0026 | 0.004 | 0.1649 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.001 | 0.0006 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0007 | 0.0021 |
Giardia lamblia | Sodium/hydrogen exchanger 3 | 0.0016 | 0.0019 | 0.374 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0198 | 0.0387 | 0.0386 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.001 | 0.0007 | 0.0004 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0072 | 0.0132 | 0.0132 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0105 | 0.02 | 0.0593 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0056 | 0.01 | 0.01 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0114 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.0018 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 nhe2 | 0.0016 | 0.0019 | 0.0041 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.001 | 0.0006 | 0.0018 |
Plasmodium falciparum | kinesin-5 | 0.0027 | 0.0041 | 0.1938 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.007 | 0.0128 | 0.0374 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Schistosoma mansoni | gabp alpha | 0.007 | 0.0128 | 0.0391 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.001 | 0.0007 | 0.0004 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.001 | 0.0007 | 0.0005 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0078 | 0.0222 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0056 | 0.01 | 0.0307 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.01 | 0.0189 | 0.0576 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.002 | 0.0027 | 0.1113 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0013 | 0.0012 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.001 | 0.0007 | 0.0004 |
Schistosoma mansoni | sodium/hydrogen exchanger 2 (nhe2) | 0.0016 | 0.0019 | 0.0059 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.001 | 0.0007 | 0.0085 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0105 | 0.02 | 0.0593 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0036 | 0.0111 |
Loa Loa (eye worm) | sodium/hydrogen exchanger | 0.0016 | 0.0019 | 0.0018 |
Echinococcus multilocularis | sodium:hydrogen exchanger | 0.0016 | 0.0019 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0016 | 0.0019 | 0.0041 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0094 | 0.0178 | 0.0525 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0054 | 0.0147 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.001 | 0.0007 | 0.0004 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0073 | 0.0135 | 0.0395 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.007 | 0.0128 | 0.0127 |
Echinococcus granulosus | Solute carrier family 22 5 | 0.1023 | 0.2057 | 0.6269 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.1626 | 0.3278 | 0.3277 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.001 | 0.0007 | 0.0004 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0036 | 0.1636 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.001 | 0.0006 | 0.0018 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 nhe2 | 0.0016 | 0.0019 | 0.0041 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0126 | 0.0242 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0078 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0114 | 0.0347 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0023 | 0.0033 | 0.0101 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0036 | 0.0036 |
Echinococcus granulosus | nervana 2 | 0.001 | 0.0007 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0036 | 0.0111 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.001 | 0.0006 | 0.0018 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0009 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.0354 | 0.1079 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.001 | 0.0006 | 0.0018 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0011 | 0.0008 | 0.034 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0114 | 0.0114 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.001 | 0.0006 | 0.0005 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.001 | 0.0007 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.02 | 0.0199 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0027 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0178 | 0.0177 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0023 | 0.0033 | 0.0101 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.001 | 0.0007 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.004 | 0.0039 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.002 | 0.0027 | 0.1113 |
Onchocerca volvulus | Sodium\/hydrogen exchanger homolog | 0.0016 | 0.0019 | 0.0308 |
Brugia malayi | Peptidase family M1 containing protein | 0.0224 | 0.044 | 0.044 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0054 | 0.0147 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0105 | 0.02 | 0.0199 |
Trypanosoma brucei | aminopeptidase, putative | 0.01 | 0.0189 | 0.7791 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0054 | 0.0165 |
Brugia malayi | Ets-domain containing protein | 0.007 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0114 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0131 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0036 | 0.1475 |
Echinococcus multilocularis | ets variant gene 4 | 0.001 | 0.0007 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0114 | 0.0347 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0126 | 0.0242 | 0.0739 |
Brugia malayi | Protein kinase domain containing protein | 0.0016 | 0.0019 | 0.0019 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0016 | 0.0019 | 0.0772 |
Entamoeba histolytica | aminopeptidase, putative | 0.0126 | 0.0242 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0094 | 0.0178 | 0.5 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0013 | 0.0013 | 0.0021 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.001 | 0.0007 | 0.0006 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0034 | 0.0054 | 0.0054 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.001 | 0.0007 | 0.0005 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.001 | 0.0007 | 0.0004 |
Trichomonas vaginalis | AGC family protein kinase | 0.0016 | 0.0019 | 0.0776 |
Schistosoma mansoni | kinesin eg-5 | 0.0027 | 0.0041 | 0.0126 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0042 | 0.0071 | 0.02 |
Schistosoma mansoni | endothelin-converting enzyme-related | 0.0023 | 0.0033 | 0.0101 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0073 | 0.0135 | 0.0395 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0105 | 0.02 | 0.02 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0094 | 0.0178 | 0.0525 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0114 | 0.0347 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0036 | 0.0111 |
Toxoplasma gondii | peptidase family M13 protein | 0.0094 | 0.0178 | 0.9384 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0042 | 0.0071 | 0.02 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0036 | 0.1636 |
Brugia malayi | Peptidase family M13 containing protein | 0.0094 | 0.0178 | 0.0178 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0131 | 0.013 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.002 | 0.0027 | 0.0027 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.001 | 0.0006 | 0.0006 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.01 | 0.0189 | 0.7791 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0189 | 0.0188 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.4946 | 1 | 1 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.01 | 0.0189 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0128 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0054 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0108 | 0.0107 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.002 | 0.0027 | 0.1113 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0126 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0125 | 0.0124 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.01 | 0.0189 | 0.7409 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0132 | 0.0132 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0009 | 0.0008 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0126 | 0.0242 | 0.0723 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0036 | 0.0111 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0011 | 0.0008 | 0.0025 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.001 | 0.0006 | 0.0006 |
Trypanosoma cruzi | Protein kinase B | 0.0011 | 0.0008 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0178 | 0.0177 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0019 | 0.0018 |
Entamoeba histolytica | kinesin, putative | 0.0027 | 0.0041 | 0.1703 |
Echinococcus granulosus | protein C ets 2 | 0.001 | 0.0007 | 0.0004 |
Schistosoma mansoni | transient receptor potential channel | 0.011 | 0.021 | 0.064 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0009 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0054 | 0.0165 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0014 | 0.0014 | 0.0589 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0054 | 0.0147 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0078 | 0.0078 |
Brugia malayi | Kinesin motor domain containing protein | 0.0027 | 0.0041 | 0.0041 |
Onchocerca volvulus | 0.0047 | 0.0081 | 0.1734 | |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0131 | 0.013 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0036 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0006 | 0.0005 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 36 uM | Inhibitory activity against histamine release from antigen-challenged, sensitized human basophils | ChEMBL. | 2415706 |
IC50 (functional) | = 36 uM | Inhibitory activity against histamine release from antigen-challenged, sensitized human basophils | ChEMBL. | 2415706 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.