Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin dm0 | 0.0033 | 0.4012 | 0.4012 |
Schistosoma mansoni | lamin | 0.0033 | 0.4012 | 0.4012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.4012 | 0.4012 |
Schistosoma mansoni | intermediate filament proteins | 0.0033 | 0.4012 | 0.4012 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.5325 | 0.5325 |
Echinococcus granulosus | intermediate filament protein | 0.0033 | 0.4012 | 0.4012 |
Onchocerca volvulus | 0.0033 | 0.4012 | 0.5 | |
Echinococcus multilocularis | lamin | 0.0033 | 0.4012 | 0.4012 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0056 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0033 | 0.4012 | 0.4012 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.9914 | 0.9914 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.5325 | 0.5325 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.4012 | 0.4012 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.4012 | 0.4012 |
Echinococcus granulosus | lamin | 0.0033 | 0.4012 | 0.4012 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.4012 | 0.4012 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0018 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.9914 | 0.9914 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.5325 | 0.5325 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0018 | 0.0019 | 0.0019 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.9914 | 0.9914 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.9914 | 0.9914 |
Echinococcus multilocularis | musashi | 0.0033 | 0.4012 | 0.4012 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.4012 | 0.4012 |
Echinococcus multilocularis | lamin dm0 | 0.0033 | 0.4012 | 0.4012 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0056 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0056 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0056 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0056 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.3855 | 0.3855 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0056 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 0.4012 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.