Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | g-protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | myosin xvIII | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | biogenic amine receptor | 0.0042 | 0.0216 | 0.0284 |
Giardia lamblia | Hypothetical protein | 0.033 | 0.2484 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0559 | 0.4287 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | G protein-coupled receptor | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Brugia malayi | ORL1-like opioid receptor | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0559 | 0.4287 | 0.4287 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | opsin-like receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0097 | 0.0097 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | serotonin receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | g protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | hypothetical protein | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1206 | 0.2646 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0559 | 0.4287 | 1 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | fmrfamide receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0559 | 0.4287 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.055 | 0.4213 | 0.9706 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0097 | 0.0097 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | glutaminase | 0.027 | 0.2015 | 0.2015 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.055 | 0.4213 | 0.9706 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | opsin-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.241 | 0.241 |
Echinococcus multilocularis | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Loa Loa (eye worm) | hypothetical protein | 0.1285 | 1 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | g protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Melatonin receptor type 1A | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | G-protein coupled receptor | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Serotonin receptor | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | 6 phosphofructo 2 kinase:fructose 2 | 0.0559 | 0.4287 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | somatostatin receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0141 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0094 | 0.0094 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | serotonin receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0042 | 0.0216 | 0.0216 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0559 | 0.4287 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | neuropeptide F receptor | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | serotonin receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | glutaminase 2 | 0.027 | 0.2015 | 0.2015 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | putative neuropeptide receptor | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0141 | 0.0105 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | neuropeptide F receptor | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Dopamine receptor protein 1 | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | Dopamine receptor | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Giardia lamblia | Hypothetical protein | 0.033 | 0.2484 | 0.5 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Serotonin receptor | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | glutaminase DH11.1 | 0.027 | 0.2015 | 0.2015 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0042 | 0.0216 | 0.0284 |
Trichomonas vaginalis | glutaminase, putative | 0.027 | 0.2015 | 1 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0042 | 0.0216 | 0.0284 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0141 | 0.5 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.033 | 0.2484 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1206 | 0.2646 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0141 | 0.0105 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0132 | 0.0083 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.055 | 0.4213 | 0.9706 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0141 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | fmrfamide receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0141 | 0.0105 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0141 | 0.0105 |
Schistosoma mansoni | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | sulfakinin receptor protein | 0.1285 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Echinococcus granulosus | somatostatin receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0032 | 0.0141 | 0.0105 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | orexin receptor type 2 | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | g protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.033 | 0.2484 | 0.5 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0141 | 0.0141 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | G-protein coupled receptor | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | RE15519p | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | GnHR receptor homolog | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | opsin-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0141 | 0.0105 |
Brugia malayi | Pre-SET motif family protein | 0.0225 | 0.1658 | 0.1658 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | g protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | follicle stimulating hormone receptor | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | g protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | biogenic amine receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0042 | 0.0216 | 0.0284 |
Mycobacterium ulcerans | hypothetical protein | 0.033 | 0.2484 | 1 |
Onchocerca volvulus | 0.0559 | 0.4287 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | geminin | 0.0168 | 0.1206 | 0.2646 |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | glutaminase | 0.027 | 0.2015 | 0.4576 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0097 | 0.0097 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | neuropeptide s receptor | 0.0042 | 0.0216 | 0.0284 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0042 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0256 | 0.1902 | 0.4307 | |
Brugia malayi | larval opioid receptor | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | allatostatin A receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | sex peptide receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | histamine h1 receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | biogenic amine receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Schistosoma mansoni | amine GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.055 | 0.4213 | 0.4213 |
Echinococcus granulosus | allatostatin A receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0042 | 0.0216 | 0.0284 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | neuropeptide receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.0559 | 0.4287 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0141 | 0.0105 |
Schistosoma mansoni | adenoreceptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | g protein coupled receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0042 | 0.0216 | 0.0216 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0042 | 0.0216 | 0.0284 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0141 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0042 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | sex peptide receptor | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0097 | 0.0097 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0216 | 0.0284 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Echinococcus granulosus | fmrfamide receptor | 0.0042 | 0.0216 | 0.0284 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.055 | 0.4213 | 0.9706 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1206 | 0.2646 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0559 | 0.4287 | 1 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0042 | 0.0216 | 0.0284 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0042 | 0.0216 | 0.0284 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0225 | 0.1658 | 0.1658 |
Brugia malayi | AKH receptor | 0.0042 | 0.0216 | 0.0216 |
Onchocerca volvulus | 0.0042 | 0.0216 | 0.0284 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0216 | 0.0216 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 0.0000022 M | Cytotoxicity against P388 leukemia | ChEMBL. | 8389875 |
IC50 (binding) | 0 uM | Inhibition of DNA topoisomerase II from Rat Liver measured as 50% reduction in the amount of minicircle DNA relative to the control; Not tested | ChEMBL. | 8389875 |
IC50 (binding) | > 100 uM | Drug concentration needed to produce a 50% reduction of bovine brain tubulin polymerization relative to the control | ChEMBL. | 8389875 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.