Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Leishmania major | phosphoglycan beta 1,3 galactosyltransferase 5 | 0.0025 | 0.0273 | 0.3295 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0013 | 0.0071 | 0.0021 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0684 | 0.0684 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0031 | 0.0017 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | oxidoreductase | 0.0015 | 0.0098 | 0.0096 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0031 | 0.0017 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0756 | 0.2433 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0031 | 0.0017 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0667 | 0.098 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0031 | 0.0017 |
Echinococcus granulosus | GPCR family 2 | 0.0049 | 0.0664 | 0.0662 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0038 | 0.0474 | 0.0886 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0015 | 0.0098 | 0.0114 |
Brugia malayi | hypothetical protein | 0.0483 | 0.7778 | 0.7778 |
Echinococcus granulosus | muscleblind protein | 0.0619 | 1 | 1 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.0092 |
Loa Loa (eye worm) | insulin-degrading enzyme | 0.0025 | 0.0273 | 0.0271 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0015 | 0.0098 | 0.0114 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0031 | 0.0029 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0098 | 0.0098 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.136 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0015 | 0.0098 | 0.006 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0098 | 0.136 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0031 | 0.0029 |
Brugia malayi | RNA binding protein | 0.0198 | 0.3108 | 0.3108 |
Echinococcus granulosus | 3'partial|nardilysin | 0.0025 | 0.0273 | 0.0271 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0031 | 0.0017 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0357 | 0.0356 |
Echinococcus multilocularis | GPCR, family 2 | 0.0049 | 0.0664 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0758 | 0.0756 |
Onchocerca volvulus | 0.0013 | 0.0071 | 0.0051 | |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0566 | 0.0826 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0031 | 0.0029 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0045 | 0.0592 | 0.059 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0098 | 0.0114 |
Toxoplasma gondii | propionate-CoA ligase | 0.0015 | 0.0098 | 0.0259 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0013 | 0.0071 | 0.0021 |
Onchocerca volvulus | 0.0029 | 0.033 | 0.0386 | |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0045 | 0.0592 | 0.059 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0566 | 0.0826 |
Echinococcus multilocularis | nardilysin | 0.0025 | 0.0273 | 0.0271 |
Echinococcus multilocularis | expressed conserved protein | 0.0098 | 0.1469 | 0.1467 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0194 | 0.3045 | 0.6529 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0031 | 0.0017 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0031 | 0.0029 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0194 | 0.3045 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0031 | 0.0029 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0031 | 0.0029 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0105 | 0.1573 | 0.1571 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0031 | 0.0031 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0106 | 0.16 | 0.2391 |
Trypanosoma cruzi | peptidase, putative | 0.0025 | 0.0273 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0474 | 0.0473 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0667 | 0.0666 |
Chlamydia trachomatis | insulinase family protease III | 0.0025 | 0.0273 | 0.068 |
Toxoplasma gondii | rhoptry metalloprotease toxolysin TLN1 | 0.0025 | 0.0273 | 0.0836 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0015 | 0.0098 | 0.0092 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0013 | 0.0071 | 0.0069 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0015 | 0.0098 | 0.0092 |
Toxoplasma gondii | insulysin, putative | 0.0024 | 0.0252 | 0.0769 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0015 | 0.0098 | 0.0114 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.015 | 0.231 | 0.2309 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0105 | 0.1573 | 0.1571 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.3108 | 0.4672 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0684 | 0.0682 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0098 | 0.136 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0051 | 0.0684 | 0.4083 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0098 | 0.0098 |
Trypanosoma brucei | peptidase, putative | 0.0025 | 0.0273 | 1 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0015 | 0.0098 | 0.0096 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.3108 | 0.4672 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0592 | 0.059 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0667 | 0.0666 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0194 | 0.3045 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0031 | 0.0031 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0015 | 0.0098 | 0.0114 |
Onchocerca volvulus | 0.0015 | 0.0098 | 0.0087 | |
Onchocerca volvulus | 0.0013 | 0.0071 | 0.0051 | |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0031 | 0.0031 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0667 | 0.0666 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0031 | 0.0031 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0105 | 0.1573 | 0.1573 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.0448 |
Schistosoma mansoni | nardilysin (M16 family) | 0.0025 | 0.0273 | 0.0383 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0045 | 0.0592 | 0.059 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0015 | 0.0098 | 0.0092 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0357 | 0.0356 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0015 | 0.0098 | 0.0259 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0664 | 0.0662 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0098 | 0.0448 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0013 | 0.0071 | 0.0069 |
Echinococcus multilocularis | protein patched | 0.0045 | 0.0592 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.136 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0667 | 0.098 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0051 | 0.0684 | 0.2062 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0051 | 0.0684 | 0.2079 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0098 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0474 | 0.0473 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0015 | 0.0098 | 0.0114 |
Echinococcus multilocularis | protein dispatched 1 | 0.0051 | 0.0696 | 0.0695 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0619 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0156 | 0.2411 | 0.2411 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0013 | 0.0071 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0474 | 0.0473 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.033 | 0.0329 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0194 | 0.3045 | 1 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0015 | 0.0098 | 0.0183 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0031 | 0.0029 |
Toxoplasma gondii | toxolysin TLN4 | 0.0011 | 0.004 | 0.0068 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0038 | 0.0474 | 0.1357 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0031 | 0.0031 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0198 | 0.3108 | 0.3108 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 0.2411 | 0.241 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0664 | 0.0974 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Echinococcus granulosus | 5'partial|nardilysin | 0.0011 | 0.004 | 0.0039 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0031 | 0.0029 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0015 | 0.0098 | 0.006 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0031 | 0.0029 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.136 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0015 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0667 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0664 | 0.0662 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0864 | 0.1277 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0015 | 0.0098 | 0.006 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0013 | 0.0071 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1602 | 0.1601 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0098 | 0.0096 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0015 | 0.0098 | 0.0119 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.033 | 0.033 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0194 | 0.3045 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0098 | 0.0098 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0031 | 0.0031 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.033 | 0.047 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0031 | 0.0029 |
Echinococcus granulosus | tar DNA binding protein | 0.0198 | 0.3108 | 0.3106 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.1573 | 0.1571 |
Schistosoma mansoni | hypothetical protein | 0.0107 | 0.1602 | 0.2395 |
Toxoplasma gondii | peptidase M16 inactive domain-containing protein | 0.0015 | 0.0108 | 0.0291 |
Onchocerca volvulus | 0.0015 | 0.0098 | 0.0087 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0667 | 0.098 |
Loa Loa (eye worm) | RNA binding protein | 0.0198 | 0.3108 | 0.3106 |
Loa Loa (eye worm) | glutaminase | 0.0291 | 0.4626 | 0.4625 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0098 | 0.0114 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0015 | 0.0098 | 0.006 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0031 | 0.0029 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0013 | 0.0071 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0684 | 0.0682 |
Echinococcus multilocularis | nardilysin | 0.0015 | 0.0108 | 0.0106 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0038 | 0.0474 | 0.1357 |
Brugia malayi | CHE-14 protein | 0.0045 | 0.0592 | 0.0592 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0038 | 0.0474 | 0.1357 |
Echinococcus granulosus | expressed conserved protein | 0.0098 | 0.1469 | 0.1467 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0013 | 0.0071 | 0.0021 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0667 | 0.0667 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0051 | 0.0684 | 0.1347 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0664 | 0.0974 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0051 | 0.0684 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0071 | 0.0069 |
Echinococcus granulosus | dnaJ subfamily B | 0.0413 | 0.6628 | 0.6628 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0031 | 0.0017 |
Echinococcus granulosus | nardilysin | 0.0025 | 0.0273 | 0.0271 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0015 | 0.0098 | 0.0096 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0013 | 0.0071 | 0.0021 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0051 | 0.0684 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0664 | 0.0662 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.3108 | 0.4672 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0038 | 0.0474 | 0.1376 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0015 | 0.0098 | 0.136 |
Onchocerca volvulus | 0.0483 | 0.7778 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0071 | 0.0069 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0413 | 0.6628 | 0.6628 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0098 | 0.0114 |
Onchocerca volvulus | 0.0015 | 0.0098 | 0.0087 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0015 | 0.0098 | 0.0098 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0684 | 0.0684 |
Echinococcus multilocularis | tar DNA binding protein | 0.0198 | 0.3108 | 0.3106 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0441 | 0.1262 |
Schistosoma mansoni | nardilysin (M16 family) | 0.0025 | 0.0273 | 0.0383 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0198 | 0.3108 | 0.3106 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0684 | 0.0682 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0013 | 0.0071 | 0.0077 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0049 | 0.0664 | 0.0664 |
Trypanosoma cruzi | peptidase, putative | 0.0025 | 0.0273 | 1 |
Schistosoma mansoni | insulysin (M16 family) | 0.0014 | 0.0087 | 0.0102 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0013 | 0.0071 | 0.0021 |
Trichomonas vaginalis | hypothetical protein | 0.0194 | 0.3045 | 0.6508 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.3108 | 0.4672 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0031 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0566 | 0.0826 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0051 | 0.0684 | 0.2079 |
Schistosoma mansoni | glutaminase | 0.0291 | 0.4626 | 0.697 |
Mycobacterium ulcerans | glutaminase | 0.0291 | 0.4626 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0031 | 0.0031 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0031 | 0.0029 |
Brugia malayi | glutaminase DH11.1 | 0.0291 | 0.4626 | 0.4626 |
Schistosoma mansoni | hypothetical protein | 0.0413 | 0.6628 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0051 | 0.0684 | 0.1347 |
Brugia malayi | TAR-binding protein | 0.0198 | 0.3108 | 0.3108 |
Echinococcus multilocularis | muscleblind protein | 0.0619 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0051 | 0.0684 | 1 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0013 | 0.0071 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0619 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0107 | 0.1602 | 0.1602 |
Schistosoma mansoni | patched 1 | 0.0045 | 0.0592 | 0.0866 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.2825 | 0.4245 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0015 | 0.0098 | 0.0259 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0051 | 0.0684 | 0.1347 |
Echinococcus multilocularis | nardilysin | 0.0025 | 0.0273 | 0.0271 |
Brugia malayi | insulin-degrading enzyme | 0.0025 | 0.0273 | 0.0273 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.2825 | 0.4245 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0015 | 0.0098 | 0.006 |
Onchocerca volvulus | 0.0015 | 0.0098 | 0.0087 | |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0013 | 0.0071 | 0.0021 |
Loa Loa (eye worm) | glutaminase 2 | 0.0291 | 0.4626 | 0.4625 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0031 | 0.0031 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0015 | 0.0098 | 0.0114 |
Schistosoma mansoni | tar DNA-binding protein | 0.0198 | 0.3108 | 0.4672 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0045 | 0.0592 | 0.059 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.015 | 0.231 | 0.2309 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0013 | 0.0071 | 0.0168 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0051 | 0.0684 | 0.4083 |
Brugia malayi | AMP-binding enzyme family protein | 0.0051 | 0.0684 | 0.0684 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0015 | 0.0098 | 0.0114 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0051 | 0.0684 | 0.4083 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0031 | 0.0029 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0031 | 0.0031 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0013 | 0.0071 | 0.0069 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0031 | 0.0029 |
Echinococcus granulosus | geminin | 0.0181 | 0.2825 | 0.2824 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0049 | 0.0664 | 0.0664 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.0448 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0441 | 0.1262 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0031 | 0.0029 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0441 | 0.1262 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0071 | 0.0071 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0051 | 0.0684 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0015 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0156 | 0.2411 | 0.241 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0357 | 0.0511 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0013 | 0.0071 | 0.0168 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0031 | 0.0029 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0194 | 0.3045 | 1 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0015 | 0.0098 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Echinococcus granulosus | insulin degrading enzyme | 0.0025 | 0.0273 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0483 | 0.7778 | 0.7778 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0474 | 0.0473 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0015 | 0.0098 | 0.0096 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0105 | 0.1573 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0031 | 0.0017 |
Toxoplasma gondii | sporozoite developmental protein | 0.0025 | 0.0273 | 0.0836 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0049 | 0.0664 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0664 | 0.0974 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0667 | 0.0666 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0051 | 0.0684 | 0.1347 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0049 | 0.0664 | 0.0662 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | dihydropteridine reductase | 0.0013 | 0.0071 | 0.0077 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0031 | 0.0029 |
Loa Loa (eye worm) | TAR-binding protein | 0.0198 | 0.3108 | 0.3106 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0031 | 0.0017 |
Schistosoma mansoni | insulysin unit 3 (M16 family) | 0.0025 | 0.0273 | 0.0383 |
Trichomonas vaginalis | glutaminase, putative | 0.0291 | 0.4626 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0051 | 0.0684 | 0.1347 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0031 | 0.0017 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0051 | 0.0684 | 0.1347 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0031 | 0.0029 |
Mycobacterium ulcerans | hypothetical protein | 0.0051 | 0.0684 | 0.1347 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0664 | 0.0974 |
Echinococcus multilocularis | geminin | 0.0181 | 0.2825 | 0.2824 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0031 | 0.0017 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0051 | 0.0684 | 0.2062 |
Onchocerca volvulus | 0.0051 | 0.0684 | 0.0843 | |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0031 | 0.0017 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0049 | 0.0664 | 0.0662 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0031 | 0.0029 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0015 | 0.0098 | 0.006 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0015 | 0.0098 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0619 | 1 | 1 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0015 | 0.0098 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0474 | 0.0473 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0015 | 0.0098 | 0.0096 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0156 | 0.2411 | 0.2411 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0031 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0031 | 0.0029 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0194 | 0.3045 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0031 | 0.0029 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0357 | 0.0511 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0015 | 0.0098 | 0.0114 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0566 | 0.0826 |
Schistosoma mansoni | insulysin unit 3 (M16 family) | 0.0025 | 0.0273 | 0.0383 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0031 | 0.0029 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0194 | 0.3045 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0592 | 0.1091 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0013 | 0.0071 | 0.0069 |
Echinococcus multilocularis | insulin degrading enzyme | 0.0025 | 0.0273 | 0.0271 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0036 | 0.0441 | 0.1262 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.