Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 1 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0014 | 0.2525 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 1 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 1 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 1 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 1 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 1 | 0.5 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 1 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 1 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 1 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 1 | 0.5 |
Onchocerca volvulus | 0.0014 | 0.2525 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 1 | 1 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 1 | 0.5 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0014 | 0.2525 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 1 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 1 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 1 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 1 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0014 | 0.2525 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 1 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 1 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.