Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.8971 | 0.8971 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0062 | 0.8971 | 0.8971 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0062 | 0.8971 | 0.8971 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0067 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0067 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.8971 | 0.8971 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0067 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0062 | 0.8971 | 0.8971 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0062 | 0.8971 | 0.8971 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.8971 | 0.8971 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0062 | 0.8971 | 0.8971 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | unspecified product | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0067 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0062 | 0.8971 | 0.8971 |
Loa Loa (eye worm) | RNA binding protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0062 | 0.8971 | 0.8971 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0067 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0067 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0067 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.